CN103989739A - Externally applied preparation mainly prepared from coal tar and preparation method thereof - Google Patents
Externally applied preparation mainly prepared from coal tar and preparation method thereof Download PDFInfo
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- CN103989739A CN103989739A CN201410207921.5A CN201410207921A CN103989739A CN 103989739 A CN103989739 A CN 103989739A CN 201410207921 A CN201410207921 A CN 201410207921A CN 103989739 A CN103989739 A CN 103989739A
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Abstract
The invention discloses an externally applied preparation mainly prepared from coal tar and a preparation method thereof. According to the formula, the externally applied preparation comprises the following medicines in parts by weight; 0.5 to 1.5g of coal tar, 58 to 62g of fatty alcohol polyoxyethylene lauryl ether sulfate sodium, 0.5 to 1.5g of monoethanolamine oleate, 3 to 7g of cocoamidopropyl betaine, 1 to 3g of cocamidopropyl dimethylamine oxide, 0.5 to 1.5g of cortex pseudolaricis, 0.5 to 1.5g of radix sophorae flavescentis, 0.5 to 1.5g of borneol, 0.5 to 1.5g of licorice extract and 21 to 25g of deionized water. The externally applied preparation is simple in formula, low in price, has good effects and hardly causes side effects.
Description
Technical field
The present invention relates to field of medicaments, especially a kind of external preparation taking coal tar as main component and preparation method thereof.
Background technology
Compound recipe coal tar is one of the product in the raw gas that generates of coking industry pyrolysis of coal, its product is black viscous solution shape at normal temperatures and pressures, has off-odor, claims again tar, its composition is very complicated, is to be in most cases used after being separated specially, purified by coal-tar industry.
Compound recipe coal tar and Chinese medicine science compatibility, make through special process, and the compound recipe coal tar lotion of making, can all have inhibitory action to the generation of the mitosis number of smegma, epidermal basal cell and squama.Can reduce the synthetic sebum of sebaceous gland and suppress its division.Chinese medicine in formula is Chinese medicine traditional treatment prescription, through modern science compatibility, fungus is had to stronger inhibitory action, heat clearing and damp drying is antipruritic, can relax the horny layer of normal and pathology, make the callus tissue of skin discharge more acid mucopolysaccharide acid, remove the connection between keratinocyte, make squama absent-mindedness, contribute to disappearing of skin lesion.
Because coal tar is applicable to, dandruff is too much, seborrheic dermatitis.Psoriasis, can alleviate the disease such as sufferings and burning sense, especially psoriasis is had to good curative effect.In order to become it to there is curative effect and lasting effect widely, through scientific research, add Chinese medicine formula, reasonable compatibility, the compound recipe coal tar lotion of making has fast and sterilization, antipruritic, antiinflammation significantly, also can repair injured hair, improve hair quality, make hair gloss be easy to combing.Head psoriasis, seborrhea bosom dermatitis, the dandruff are had to significant curative effect.
Summary of the invention
The invention discloses a kind of external preparation taking coal tar as main component and preparation method thereof, in the formula of the external preparation described in it, form medicine and be by weight ratio: coal tar 0.5 ~ 1.5g, polyoxyethylenated alcohol sodium sulfate 58 ~ 62g, coconut oil monoethanolamine 0.5 ~ 1.5g, cocos nucifera oil acyl CAB 3 ~ 7g, cocamidopropyl propyl amide amine oxide 1 ~ 3g, Cortex Pseudolaricis 0.5 ~ 1.5g, Radix Sophorae Flavescentis 0.5 ~ 1.5g, Borneolum Syntheticum 0.5 ~ 1.5g, Radix Glycyrrhizae extract 0.5 ~ 1.5g, deionized water 21 ~ 25g.
Described a kind of external preparation taking coal tar as main component and preparation method thereof, in its formula, best in quality proportioning is: coal tar 1g, polyoxyethylenated alcohol sodium sulfate 60g, coconut oil monoethanolamine 1g, cocos nucifera oil acyl CAB 5g, cocamidopropyl propyl amide amine oxide 2g, Cortex Pseudolaricis 1g, Radix Sophorae Flavescentis 1g, Borneolum Syntheticum 1g, Radix Glycyrrhizae extract 1g, deionized water 23g.
Described a kind of external preparation taking coal tar as main component and preparation method thereof, its preparation method is: 1. the polyoxyethylenated alcohol sodium sulfate of getting recipe quantity adds deionized water, is warming up to 75 ~ 85 degrees Celsius, is stirred to completely and dissolves.
2. get formula ratio and add successively Coconut Fatty Acid Monoethanolamide, cocamido propyl betaine, cocamidopropyl propyl amide amine oxide, be stirred to completely and dissolve.
3. be cooled to 40 ~ 50 degrees Celsius, get formula ratio and add successively coal tar, Cortex Pseudolaricis, Radix Sophorae Flavescentis, Borneolum Syntheticum, Radix Glycyrrhizae extract.
4. supplement deionized water to formula ratio.
5. after cooling, pack in Packaging Bottle and get final product.
The invention has the beneficial effects as follows: not only formula is simple, cheap, and effective, and side effect is little.
Detailed description of the invention
Specific embodiment 1: a kind of external preparation taking coal tar as main component and preparation method thereof, forms medicine and be by weight ratio in its formula: coal tar 1g, polyoxyethylenated alcohol sodium sulfate 60g, coconut oil monoethanolamine 1g, cocos nucifera oil acyl CAB 5g, cocamidopropyl propyl amide amine oxide 2g, Cortex Pseudolaricis 1g, Radix Sophorae Flavescentis 1g, Borneolum Syntheticum 1g, Radix Glycyrrhizae extract 1g, deionized water 23g.
Preparation method is: 1. the polyoxyethylenated alcohol sodium sulfate of getting recipe quantity adds deionized water, is warming up to 80 degrees Celsius, is stirred to completely and dissolves.
2. get formula ratio and add successively Coconut Fatty Acid Monoethanolamide, cocamido propyl betaine, cocamidopropyl propyl amide amine oxide, be stirred to completely and dissolve.
3. be cooled to 45 degrees Celsius, get formula ratio and add successively coal tar, Cortex Pseudolaricis, Radix Sophorae Flavescentis, Borneolum Syntheticum, Radix Glycyrrhizae extract.
Specific embodiment 2: a kind of external preparation taking coal tar as main component and preparation method thereof, forms medicine and be by weight ratio in its formula: coal tar 1.2g, polyoxyethylenated alcohol sodium sulfate 61g, coconut oil monoethanolamine 1.2g, cocos nucifera oil acyl CAB 6g, cocamidopropyl propyl amide amine oxide 3g, Cortex Pseudolaricis 1.2g, Radix Sophorae Flavescentis 1.2g, Borneolum Syntheticum 1.2g, Radix Glycyrrhizae extract 1.2g, deionized water 24g.
Preparation method is: 1. the polyoxyethylenated alcohol sodium sulfate of getting recipe quantity adds deionized water, is warming up to 82 degrees Celsius, is stirred to completely and dissolves.
2. get formula ratio and add successively Coconut Fatty Acid Monoethanolamide, cocamido propyl betaine, cocamidopropyl propyl amide amine oxide, be stirred to completely and dissolve.
3. be cooled to 47 degrees Celsius, get formula ratio and add successively coal tar, Cortex Pseudolaricis, Radix Sophorae Flavescentis, Borneolum Syntheticum, Radix Glycyrrhizae extract.
Specific embodiment 3: a kind of external preparation taking coal tar as main component and preparation method thereof, forms medicine and be by weight ratio in its formula: coal tar 0.6g, polyoxyethylenated alcohol sodium sulfate 59g, coconut oil monoethanolamine 0.6g, cocos nucifera oil acyl CAB 5g, cocamidopropyl propyl amide amine oxide 2g, Cortex Pseudolaricis 0.6g, Radix Sophorae Flavescentis 0.6g, Borneolum Syntheticum 0.6g, Radix Glycyrrhizae extract 0.6g, deionized water 22g.
Preparation method is: 1. the polyoxyethylenated alcohol sodium sulfate of getting recipe quantity adds deionized water, is warming up to 79 degrees Celsius, is stirred to completely and dissolves.
2. get formula ratio and add successively Coconut Fatty Acid Monoethanolamide, cocamido propyl betaine, cocamidopropyl propyl amide amine oxide, be stirred to completely and dissolve.
3. be cooled to 41 degrees Celsius, get formula ratio and add successively coal tar, Cortex Pseudolaricis, Radix Sophorae Flavescentis, Borneolum Syntheticum, Radix Glycyrrhizae extract.
Claims (3)
1. external preparation taking coal tar as main component and preparation method thereof, is characterized in that: in the formula of described external preparation, forming medicine is by weight ratio: coal tar 0.5 ~ 1.5g, polyoxyethylenated alcohol sodium sulfate 58 ~ 62g, coconut oil monoethanolamine 0.5 ~ 1.5g, cocos nucifera oil acyl CAB 3 ~ 7g, cocamidopropyl propyl amide amine oxide 1 ~ 3g, Cortex Pseudolaricis 0.5 ~ 1.5g, Radix Sophorae Flavescentis 0.5 ~ 1.5g, Borneolum Syntheticum 0.5 ~ 1.5g, Radix Glycyrrhizae extract 0.5 ~ 1.5g, deionized water 21 ~ 25g.
2. a kind of external preparation taking coal tar as main component according to claim 1 and preparation method thereof, is characterized in that: in formula, best in quality proportioning is: coal tar 1g, polyoxyethylenated alcohol sodium sulfate 60g, coconut oil monoethanolamine 1g, cocos nucifera oil acyl CAB 5g, cocamidopropyl propyl amide amine oxide 2g, Cortex Pseudolaricis 1g, Radix Sophorae Flavescentis 1g, Borneolum Syntheticum 1g, Radix Glycyrrhizae extract 1g, deionized water 23g.
3. a kind of external preparation taking coal tar as main component according to claim 1 and preparation method thereof, it is characterized in that: its preparation method is: the polyoxyethylenated alcohol sodium sulfate that a. gets recipe quantity adds deionized water, be warming up to 75 ~ 85 degrees Celsius, be stirred to completely and dissolve;
B. get formula ratio and add successively Coconut Fatty Acid Monoethanolamide, cocamido propyl betaine, cocamidopropyl propyl amide amine oxide, be stirred to completely and dissolve;
C. be cooled to 40 ~ 50 degrees Celsius, get formula ratio and add successively coal tar, Cortex Pseudolaricis, Radix Sophorae Flavescentis, Borneolum Syntheticum, Radix Glycyrrhizae extract;
D. supplement deionized water to formula ratio;
E. after cooling, pack in Packaging Bottle and get final product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410207921.5A CN103989739A (en) | 2014-05-18 | 2014-05-18 | Externally applied preparation mainly prepared from coal tar and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410207921.5A CN103989739A (en) | 2014-05-18 | 2014-05-18 | Externally applied preparation mainly prepared from coal tar and preparation method thereof |
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| CN103989739A true CN103989739A (en) | 2014-08-20 |
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| CN201410207921.5A Pending CN103989739A (en) | 2014-05-18 | 2014-05-18 | Externally applied preparation mainly prepared from coal tar and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112603861A (en) * | 2021-01-14 | 2021-04-06 | 澳美制药厂有限公司 | Head detergent and preparation method thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1895272A (en) * | 2006-06-28 | 2007-01-17 | 南京中医药大学 | Coal-tar externally-applied gel for treating psoriasis and its preparation |
| CN1942178A (en) * | 2004-02-19 | 2007-04-04 | 奥克塞尔公司 | Topical formulations for the treatment of skin conditions |
| CN101810641A (en) * | 2009-02-25 | 2010-08-25 | 北京利乐生制药科技有限公司 | External preparation taking coal tar as main component and preparation method thereof |
| CN103695216A (en) * | 2013-11-20 | 2014-04-02 | 青岛晨讯通商贸有限公司 | Itching-relieving bath lotion |
-
2014
- 2014-05-18 CN CN201410207921.5A patent/CN103989739A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1942178A (en) * | 2004-02-19 | 2007-04-04 | 奥克塞尔公司 | Topical formulations for the treatment of skin conditions |
| CN1895272A (en) * | 2006-06-28 | 2007-01-17 | 南京中医药大学 | Coal-tar externally-applied gel for treating psoriasis and its preparation |
| CN101810641A (en) * | 2009-02-25 | 2010-08-25 | 北京利乐生制药科技有限公司 | External preparation taking coal tar as main component and preparation method thereof |
| CN103695216A (en) * | 2013-11-20 | 2014-04-02 | 青岛晨讯通商贸有限公司 | Itching-relieving bath lotion |
Non-Patent Citations (1)
| Title |
|---|
| 李珊主编: "《皮肤性病学》", 31 August 2008 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112603861A (en) * | 2021-01-14 | 2021-04-06 | 澳美制药厂有限公司 | Head detergent and preparation method thereof |
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Application publication date: 20140820 |
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