CN103971574B - Ultrasonic guidance tumor puncture training simulation system - Google Patents
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- 238000004088 simulation Methods 0.000 title claims abstract description 21
- 238000012549 training Methods 0.000 title claims abstract description 21
- 239000000523 sample Substances 0.000 claims abstract description 32
- 238000002604 ultrasonography Methods 0.000 claims abstract description 27
- 230000004927 fusion Effects 0.000 claims abstract description 10
- 238000012545 processing Methods 0.000 claims abstract description 4
- 238000003780 insertion Methods 0.000 claims description 14
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- 239000003550 marker Substances 0.000 claims description 10
- 238000002679 ablation Methods 0.000 claims description 6
- 230000005672 electromagnetic field Effects 0.000 claims description 6
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- 230000002980 postoperative effect Effects 0.000 claims description 3
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- 230000002792 vascular Effects 0.000 description 6
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- 210000000988 bone and bone Anatomy 0.000 description 2
- 210000004185 liver Anatomy 0.000 description 2
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- 210000003484 anatomy Anatomy 0.000 description 1
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Abstract
本发明公开了一种超声引导肿瘤穿刺训练仿真系统,包括弹性假体;仿真超声探针;仿真穿刺针;电磁追踪设备,其获取仿真超声探针和仿真穿刺针的位置和方向信息,将该信息传送至影像引导模块;术前CT图像模块;以及影像引导模块,包括处理模块、配准模块、实时CT切面图像模块、仿真超声图像模块、显示模块和融合模块,其中,在所述配准之后,仿真穿刺针插入假体执行仿真穿刺手术。本发明由于采用了仿真超声探针和仿真穿刺针,大大降低了仿真系统的成本,能够以低成本方式满足复杂技能训练的需要。
The invention discloses an ultrasound-guided tumor puncture training simulation system, which includes an elastic prosthesis; a simulated ultrasonic probe; a simulated puncture needle; The information is sent to the image guidance module; the preoperative CT image module; and the image guidance module, including a processing module, a registration module, a real-time CT slice image module, a simulated ultrasound image module, a display module and a fusion module, wherein, in the registration Afterwards, the simulated puncture needle is inserted into the prosthesis to perform a simulated puncture operation. Because the present invention adopts the simulated ultrasonic probe and the simulated puncture needle, the cost of the simulated system is greatly reduced, and the requirement of complex skill training can be met in a low-cost manner.
Description
技术领域technical field
本发明涉及医学技术领域,具体涉及超声引导肿瘤穿刺训练仿真系统。The invention relates to the field of medical technology, in particular to an ultrasound-guided tumor puncture training simulation system.
背景技术Background technique
超声(US)引导肿瘤穿刺技术已经广泛应用于肿瘤治疗领域。穿刺手术需要医生具有熟练的技能,尤其是对手眼协调操作要求比较高。因此,需要发展各种训练方法来强化医生的手眼协调能力。目前,有一些仿真系统用来执行术前规划和术中模拟。但是,这些系统都需要用到超声机器,且在手术室内执行模拟,一方面超声机器是非常昂贵的,另一方面,在手术室内进行模拟会受到许多非技术因素的影响,使得模拟效果不理想。而且,当前的仿真系统仅能用来训练布针技能,不能满足更复杂的技能训练的要求,诸如选择优化穿刺路径、进针角度和进针深度等。因此,迫切需要一种在手术室外的低成本的可满足复杂技能训练的仿真系统。Ultrasound (US)-guided tumor puncture technology has been widely used in the field of tumor therapy. The puncture operation requires the skilled skills of the doctor, especially the high requirement for hand-eye coordination. Therefore, it is necessary to develop various training methods to strengthen the hand-eye coordination ability of doctors. Currently, there are several simulation systems used to perform preoperative planning and intraoperative simulation. However, these systems all require the use of ultrasound machines, and the simulation is performed in the operating room. On the one hand, the ultrasound machine is very expensive. On the other hand, the simulation in the operating room will be affected by many non-technical factors, making the simulation effect unsatisfactory. . Moreover, the current simulation system can only be used to train needle placement skills, and cannot meet the requirements of more complex skill training, such as selecting the optimal puncture path, needle insertion angle, and needle insertion depth. Therefore, there is an urgent need for a low-cost simulation system that can satisfy complex skill training outside the operating room.
发明内容Contents of the invention
本发明实施例所要解决的技术问题在于,提供一种超声引导肿瘤穿刺训练仿真系统,使得以低成本方式满足复杂技能训练的需要。The technical problem to be solved by the embodiments of the present invention is to provide an ultrasound-guided tumor puncture training simulation system so as to meet the needs of complex skill training in a low-cost manner.
为解决上述技术问题,本发明提供了一种超声引导肿瘤穿刺训练仿真系统,包括:弹性假体,其模拟患者结构;仿真超声探针,其能够在假体上移动以实时仿真扫描;仿真穿刺针,其能够插入假体执行仿真穿刺手术;电磁追踪设备,其获取仿真超声探针和仿真穿刺针的位置和方向信息,将该信息传送至影像引导模块;术前CT图像模块,其读取及显示患者术前CT图像;以及影像引导模块。影像引导模块包括:处理模块,将由术前CT图像重构出3D影像模型;配准模块,其将术前CT图像和弹性假体配准;实时CT切面图像模块,其在所述配准之后,随着仿真超声探针在假体上移动,由术前CT图像根据仿真超声探针的位置和方向生成实时CT切面图像;仿真超声图像模块,其由实时CT切面图像生成对应的仿真超声图像;显示模块,其显示实时CT切面图像、仿真超声图像及3D影像模型,以及融合模块,其根据仿真穿刺针的位置和方向将仿真穿刺针的实时穿刺路径融合显示在实时CT切面图像、仿真超声图像及3D影像模型上,穿刺路径示出仿真穿刺针的插入点、插入角度、插入深度以及消融场。在所述配准之后,仿真穿刺针插入假体执行仿真穿刺手术。In order to solve the above technical problems, the present invention provides an ultrasound-guided tumor puncture training simulation system, including: an elastic prosthesis, which simulates the structure of the patient; a simulated ultrasonic probe, which can move on the prosthesis to simulate scanning in real time; simulate puncture Needle, which can be inserted into the prosthesis to perform simulated puncture surgery; electromagnetic tracking equipment, which obtains the position and direction information of the simulated ultrasonic probe and simulated puncture needle, and transmits the information to the image guidance module; preoperative CT image module, which reads and displaying preoperative CT images of patients; and an image guidance module. The image guidance module includes: a processing module, which will reconstruct a 3D image model from the preoperative CT image; a registration module, which will register the preoperative CT image and the elastic prosthesis; a real-time CT section image module, which will be used after the registration , as the simulated ultrasonic probe moves on the prosthesis, the preoperative CT image generates real-time CT slice images according to the position and direction of the simulated ultrasonic probe; the simulated ultrasonic image module generates corresponding simulated ultrasonic images from the real-time CT slice images A display module, which displays real-time CT slice images, simulated ultrasound images and 3D image models, and a fusion module, which fuses and displays the real-time puncture path of the simulated puncture needle on the real-time CT slice images, simulated ultrasound according to the position and direction of the simulated puncture needle On the image and 3D image model, the puncture path shows the insertion point, insertion angle, insertion depth and ablation field of the simulated puncture needle. After said registration, a simulated puncture needle is inserted into the prosthesis to perform a simulated puncture procedure.
作为优选,所述电磁追踪设备包括电磁场发生器、传感器、传感器接口单元和控制单元,控制单元控制电磁场发生器和传感器,传感器获取仿真超声探针和仿真穿刺针的位置和方位信息。Preferably, the electromagnetic tracking device includes an electromagnetic field generator, a sensor, a sensor interface unit and a control unit, the control unit controls the electromagnetic field generator and the sensor, and the sensor acquires position and orientation information of the simulated ultrasonic probe and the simulated puncture needle.
作为进一步的优选,所述传感器为6自由度传感器。As a further preference, the sensor is a 6-DOF sensor.
作为优选,所述仿真超声探针选择假体中的至少三个标记点,利用影像引导模块选择患者术前CT图像中对应的至少三个标记点,所述配准模块使用算法将这些标记点统一在同一坐标系统中以使得术前CT图像和弹性假体配准。Preferably, the simulated ultrasonic probe selects at least three marker points in the prosthesis, uses the image guidance module to select at least three corresponding marker points in the patient's preoperative CT image, and the registration module uses an algorithm to align these marker points Unified in the same coordinate system to enable registration of the preoperative CT image and the elastic prosthesis.
作为进一步的优选,所述算法包括迭代就近点算法。As a further preference, the algorithm includes an iterative closest point algorithm.
作为优选,所述影像引导模块还包括术前规划模块,其保存在术前CT图像和/或3D影像模型上规划出的仿真穿刺针插入弹性假体的预穿刺路径。Preferably, the image guidance module further includes a preoperative planning module, which saves the pre-puncture path of the simulated puncture needle inserted into the elastic prosthesis planned on the preoperative CT image and/or 3D image model.
作为优选,所述影像引导模块还包括术中观察模块,其在实时CT切面图像、仿真超声图像及3D影像模型上同时显示仿真穿刺针的预穿刺路径和实时穿刺路径。Preferably, the image guidance module further includes an intraoperative observation module, which simultaneously displays the pre-puncture path and the real-time puncture path of the simulated puncture needle on real-time CT slice images, simulated ultrasound images and 3D image models.
作为优选,所述影像引导模块还包括术后评估模块,其基于肿瘤数据和消融场数据分析肿瘤是否完全消融。Preferably, the image guidance module further includes a postoperative evaluation module, which analyzes whether the tumor is completely ablated based on the tumor data and the ablation field data.
作为优选,所述仿真超声探针和仿真穿刺针由体感游戏机的手控柄构成。Preferably, the simulated ultrasonic probe and simulated puncture needle are composed of a handle of a somatosensory game machine.
本发明由于采用了仿真超声探针和仿真穿刺针,大大降低了仿真系统的成本,能够以低成本方式满足复杂技能训练的需要。Because the present invention adopts the simulated ultrasonic probe and the simulated puncture needle, the cost of the simulated system is greatly reduced, and the requirement of complex skill training can be met in a low-cost manner.
附图说明Description of drawings
图1为本发明实施例的超声引导肿瘤穿刺训练仿真系统的结构示意图。FIG. 1 is a schematic structural diagram of an ultrasound-guided tumor puncture training simulation system according to an embodiment of the present invention.
图2为术前CT图像以及由术前CT图像重构的3D影像模型示意图,其中左上图为术前CT图像,其他图为各种3D影像模型,其中右上图示意地示出肿瘤、肝、重要血管结构的表面绘制,左下图示意地示出肿瘤、重要血管结构的表面绘制,右下图示意地示出骨骼、肿瘤、重要血管结构的表面绘制。Figure 2 is a schematic diagram of the preoperative CT image and the 3D image model reconstructed from the preoperative CT image. The upper left image is the preoperative CT image, and the other images are various 3D image models. The upper right image schematically shows the tumor, liver, The surface rendering of important vascular structures, the lower left figure schematically shows the surface rendering of tumors and important vascular structures, and the lower right figure schematically shows the surface rendering of bones, tumors, and important vascular structures.
图3为利用3D影像模型进行术前规划的示意图,图示了插入两个穿刺针来完全消融肿瘤。Figure 3 is a schematic diagram of preoperative planning using a 3D image model, illustrating the insertion of two puncture needles to completely ablate a tumor.
图4为仿真穿刺针的实时穿刺路径融合显示在实时CT切面图像、仿真超声图像及3D影像模型上的示意图,其中上方图为仿真穿刺针的实时穿刺路径融合显示在3D影像模型上,左下图为仿真穿刺针的实时穿刺路径融合显示在实时CT切面图像上,右下图为仿真穿刺针的实时穿刺路径融合显示在仿真超声图像上。Figure 4 is a schematic diagram of the real-time puncture path fusion of the simulated puncture needle displayed on the real-time CT slice image, simulated ultrasound image and 3D image model. The real-time puncture path fusion of the simulated puncture needle is displayed on the real-time CT slice image, and the lower right picture shows the real-time puncture path fusion of the simulated puncture needle displayed on the simulated ultrasound image.
具体实施方式detailed description
下面结合附图和具体实施例对本发明作进一步详细描述,但不作为对本发明的限定。The present invention will be described in further detail below in conjunction with the accompanying drawings and specific embodiments, but not as a limitation of the present invention.
图1为本发明实施例的超声引导肿瘤穿刺训练仿真系统的结构示意图。如图1所示,本发明的超声引导肿瘤穿刺训练仿真系统包括:弹性假体1,其模拟患者结构;仿真超声探针2,其能够在假体1上移动以实时仿真扫描;仿真穿刺针3,其能够插入假体1执行仿真穿刺手术;电磁追踪设备,其获取仿真超声探针2和仿真穿刺针3的位置和方向信息,将该信息传送至影像引导模块;术前CT图像模块,其读取及显示患者术前CT图像;以及影像引导模块。FIG. 1 is a schematic structural diagram of an ultrasound-guided tumor puncture training simulation system according to an embodiment of the present invention. As shown in Figure 1, the ultrasound-guided tumor puncture training simulation system of the present invention includes: an elastic prosthesis 1, which simulates the structure of the patient; a simulated ultrasonic probe 2, which can move on the prosthesis 1 to simulate scanning in real time; a simulated puncture needle 3. It can be inserted into the prosthesis 1 to perform a simulated puncture operation; the electromagnetic tracking device obtains the position and direction information of the simulated ultrasonic probe 2 and the simulated puncture needle 3, and transmits the information to the image guidance module; the preoperative CT image module, It reads and displays preoperative CT images of patients; and an image guidance module.
影像引导模块包括:Image guidance modules include:
处理模块,将由术前CT图像重构出3D影像模型,如图2中所示,示意性地示出了由术前CT图像重构的各种3D影像模型,其中右上图示意地示出肿瘤、肝、重要血管结构的表面绘制,左下图示意地示出肿瘤、重要血管结构的表面绘制,右下图示意地示出骨骼、肿瘤、重要血管结构的表面绘制;The processing module will reconstruct a 3D image model from the preoperative CT image, as shown in Figure 2, which schematically shows various 3D image models reconstructed from the preoperative CT image, and the upper right figure schematically shows the tumor The surface rendering of , liver, and important vascular structures, the lower left figure schematically shows the surface rendering of tumors and important vascular structures, and the lower right figure schematically shows the surface rendering of bones, tumors, and important vascular structures;
配准模块,其将术前CT图像和弹性假体1配准;实时CT切面图像模块,其在所述配准之后,随着仿真超声探针2在假体1上移动,由术前CT图像根据仿真超声探针2的位置和方向生成实时CT切面图像;A registration module, which registers the preoperative CT image and the elastic prosthesis 1; a real-time CT section image module, which moves on the prosthesis 1 with the simulated ultrasonic probe 2 after the registration, and is controlled by the preoperative CT The image generates a real-time CT section image according to the position and direction of the simulated ultrasonic probe 2;
仿真超声图像模块,其由实时CT切面图像生成对应的仿真超声图像;A simulated ultrasonic image module, which generates a corresponding simulated ultrasonic image from a real-time CT section image;
显示模块,其显示实时CT切面图像、仿真超声图像及3D影像模型;以及A display module, which displays real-time CT slice images, simulated ultrasound images and 3D image models; and
融合模块,其根据仿真穿刺针3的位置和方向将仿真穿刺针3的实时穿刺路径融合显示在实时CT切面图像、仿真超声图像及3D影像模型上,穿刺路径示出仿真穿刺3的插入点、插入角度、插入深度以及消融场。图4为仿真穿刺针的实时穿刺路径融合显示在实时CT切面图像、仿真超声图像及3D影像模型上的示意图,其中上方图为仿真穿刺针的实时穿刺路径融合显示在3D影像模型上,左下图为仿真穿刺针的实时穿刺路径融合显示在实时CT切面图像上,右下图为仿真穿刺针的实时穿刺路径融合显示在仿真超声图像上;The fusion module, which fuses and displays the real-time puncture path of the simulated puncture needle 3 on the real-time CT slice image, simulated ultrasound image and 3D image model according to the position and direction of the simulated puncture needle 3, the puncture path shows the insertion point of the simulated puncture 3, Insertion angle, insertion depth, and ablation field. Figure 4 is a schematic diagram of the real-time puncture path fusion of the simulated puncture needle displayed on the real-time CT slice image, simulated ultrasound image and 3D image model. The real-time puncture path fusion of the simulated puncture needle is displayed on the real-time CT slice image, and the lower right picture shows the real-time puncture path fusion of the simulated puncture needle displayed on the simulated ultrasound image;
在所述配准之后,仿真穿刺针3插入假体1执行仿真穿刺手术。After the registration, the simulated puncture needle 3 is inserted into the prosthesis 1 to perform a simulated puncture operation.
本发明由于采用了仿真超声探针2和仿真穿刺针3,大大降低了仿真系统的成本,能够以低成本方式满足复杂技能训练的需要。具体来说,本发明不需要像现有技术那样采用真实的超声设备,而是采用了仿真超声探针2和仿真穿刺针3。仿真超声探针2的作用仅仅是模拟超声探针的移动方式而已,无需其他功能。仿真穿刺针3的作用仅仅是模拟穿刺针的插入方式而已,无需其他功能。电磁追踪设备仅需获得仿真超声探针2和仿真穿刺针3的位置和方向信息,无需其他信息。在整个过程中,无需获得真实的超声图像,仅需由实时CT切面图像生成对应的仿真超声图像,这大大降低了系统的成本。Because the present invention adopts the simulated ultrasonic probe 2 and the simulated puncture needle 3, the cost of the simulated system is greatly reduced, and the need for complex skill training can be met in a low-cost manner. Specifically, the present invention does not need to use a real ultrasonic device like the prior art, but uses a simulated ultrasonic probe 2 and a simulated puncture needle 3 . The function of the simulated ultrasonic probe 2 is only to simulate the moving mode of the ultrasonic probe, and no other functions are required. The function of the simulated puncture needle 3 is only to simulate the insertion mode of the puncture needle, and no other functions are required. The electromagnetic tracking device only needs to obtain the position and direction information of the simulated ultrasound probe 2 and the simulated puncture needle 3 , without other information. During the whole process, there is no need to obtain real ultrasound images, but only corresponding simulated ultrasound images need to be generated from real-time CT slice images, which greatly reduces the cost of the system.
电磁追踪设备可以包括电磁场发生器、传感器、传感器接口单元和控制单元,控制单元控制电磁场发生器和传感器,传感器获取仿真超声探针2和仿真穿刺针3的位置和方位信息。传感器可以为各种传感器,例如6自由度传感器。The electromagnetic tracking device may include an electromagnetic field generator, a sensor, a sensor interface unit and a control unit, the control unit controls the electromagnetic field generator and the sensor, and the sensor acquires position and orientation information of the simulated ultrasound probe 2 and the simulated puncture needle 3 . The sensor can be various sensors, such as a 6-degree-of-freedom sensor.
影像引导模块允许医生对3D影像模型执行各种操作,诸如隐藏、可视化、选择、测量、移动等,从而更直观地观察解剖结构之间的复杂关系。例如,通过影像引导模块,可以计算和观察肿瘤的体积、最大直径、肿瘤与周边血管的最小距离等。The image guidance module allows doctors to perform various operations on the 3D image model, such as hiding, visualization, selection, measurement, movement, etc., so as to observe the complex relationship between anatomical structures more intuitively. For example, through the image guidance module, the volume of the tumor, the maximum diameter, the minimum distance between the tumor and the surrounding blood vessels, etc. can be calculated and observed.
在进行穿刺手术之前,必须进行图像配准。配置模块可以实现该功能。例如,仿真超声探针2选择假体1中的至少三个标记点,利用影像引导模块选择患者术前CT图像中对应的至少三个标记点,所述配准模块使用算法将这些标记点统一在同一坐标系统中以使得术前CT图像和弹性假体1配准。配准后,随着仿真超声探针2在假体1上移动,根据仿真超声探针2的位置和方向显示实时CT切面图像。所述算法可以包括各种适合的算法,优选迭代就近点算法。Image registration must be performed prior to puncture surgery. The configuration module can realize this function. For example, the simulated ultrasonic probe 2 selects at least three marker points in the prosthesis 1, uses the image guidance module to select at least three corresponding marker points in the patient's preoperative CT image, and the registration module uses an algorithm to unify these marker points The preoperative CT image and the elastic prosthesis 1 are registered in the same coordinate system. After registration, as the simulated ultrasonic probe 2 moves on the prosthesis 1, real-time CT slice images are displayed according to the position and direction of the simulated ultrasonic probe 2 . The algorithm may include various suitable algorithms, preferably an iterative nearest point algorithm.
影像引导模块还可以包括术前规划模块,其保存在术前CT图像和/或3D影像模型上规划出的仿真穿刺针3插入弹性假体1的预穿刺路径。如图3所示,其示出了利用3D影像模型进行术前规划的示意图,图示了插入两个穿刺针来完全消融肿瘤。The image guidance module may also include a preoperative planning module, which saves the pre-puncture path of the simulated puncture needle 3 inserted into the elastic prosthesis 1 planned on the preoperative CT image and/or 3D image model. As shown in FIG. 3 , which shows a schematic diagram of preoperative planning using a 3D image model, illustrating the insertion of two puncture needles to completely ablate a tumor.
影像引导模块还可以包括术中观察模块,其在实时CT切面图像、仿真超声图像及3D影像模型上同时显示仿真穿刺针3的预穿刺路径和实时穿刺路径。这样可以方便的进行术中观察,当实时穿刺路径与预穿刺路径不同时,医生通过操作及时改变仿真穿刺针3的实时穿刺路径。The image guidance module may also include an intraoperative observation module, which simultaneously displays the pre-puncture path and the real-time puncture path of the simulated puncture needle 3 on the real-time CT slice image, the simulated ultrasound image and the 3D image model. In this way, intraoperative observation can be performed conveniently. When the real-time puncture path is different from the pre-puncture path, the doctor can change the real-time puncture path of the simulated puncture needle 3 in time through operation.
影像引导模块还可以包括术后评估模块,其基于肿瘤数据和消融场数据分析肿瘤是否完全消融。The image guidance module may also include a postoperative evaluation module, which analyzes whether the tumor is completely ablated based on the tumor data and the ablation field data.
仿真超声探针2和仿真穿刺针3可以由能实现本发明目的的各种合适器件构成。发明人发现,由体感游戏机的手控柄构成仿真超声探针2和仿真穿刺针3能够大大降低仿真系统的成本。The simulated ultrasonic probe 2 and the simulated puncture needle 3 can be composed of various suitable devices that can realize the purpose of the present invention. The inventors have found that the simulated ultrasonic probe 2 and simulated puncture needle 3 formed by the handle of the somatosensory game machine can greatly reduce the cost of the simulated system.
当然,以上所述是本发明的优选实施方式,应当指出,对于本技术领域的普通技术人员来说,在不脱离本发明原理的前提下,还可以做出若干改进和润饰,这些改进和润饰也视为本发明的保护范围。Certainly, what is described above is a preferred embodiment of the present invention. It should be pointed out that for those of ordinary skill in the art, some improvements and modifications can also be made without departing from the principles of the present invention. These improvements and modifications It is also regarded as the protection scope of the present invention.
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