CN103961583A - Chinese herbal preparation for treating viral influenza and preparation method thereof - Google Patents
Chinese herbal preparation for treating viral influenza and preparation method thereof Download PDFInfo
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- 230000003612 virological effect Effects 0.000 title claims abstract description 18
- 238000002360 preparation method Methods 0.000 title claims description 8
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- 241000717679 Mosla Species 0.000 claims abstract description 5
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- 241000555682 Forsythia x intermedia Species 0.000 claims abstract 2
- 239000007788 liquid Substances 0.000 claims description 27
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 21
- 239000000203 mixture Substances 0.000 claims description 16
- 238000011282 treatment Methods 0.000 claims description 16
- 238000001914 filtration Methods 0.000 claims description 12
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- UAJTZZNRJCKXJN-UHFFFAOYSA-M sodium;2-dodecoxy-2-oxoethanesulfonate Chemical compound [Na+].CCCCCCCCCCCCOC(=O)CS([O-])(=O)=O UAJTZZNRJCKXJN-UHFFFAOYSA-M 0.000 claims description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 6
- 241000605447 Anemarrhena Species 0.000 claims description 4
- 241000245240 Lonicera Species 0.000 claims description 4
- 241000229722 Perilla <angiosperm> Species 0.000 claims description 4
- 241000219780 Pueraria Species 0.000 claims description 4
- 241000207929 Scutellaria Species 0.000 claims description 4
- OSGAYBCDTDRGGQ-UHFFFAOYSA-L calcium sulfate Chemical compound [Ca+2].[O-]S([O-])(=O)=O OSGAYBCDTDRGGQ-UHFFFAOYSA-L 0.000 claims description 4
- 210000000582 semen Anatomy 0.000 claims description 4
- 235000014435 Mentha Nutrition 0.000 claims description 3
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- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims description 3
- 229930006000 Sucrose Natural products 0.000 claims description 3
- 230000000840 anti-viral effect Effects 0.000 claims description 3
- 238000004821 distillation Methods 0.000 claims description 3
- 239000000706 filtrate Substances 0.000 claims description 3
- 239000012567 medical material Substances 0.000 claims description 3
- WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 claims description 3
- 235000010234 sodium benzoate Nutrition 0.000 claims description 3
- 239000004299 sodium benzoate Substances 0.000 claims description 3
- 239000005720 sucrose Substances 0.000 claims description 3
- 229940126678 chinese medicines Drugs 0.000 claims description 2
- 239000000463 material Substances 0.000 abstract description 2
- NEZONWMXZKDMKF-JTQLQIEISA-N Alkannin Chemical compound C1=CC(O)=C2C(=O)C([C@@H](O)CC=C(C)C)=CC(=O)C2=C1O NEZONWMXZKDMKF-JTQLQIEISA-N 0.000 abstract 1
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- 244000189548 Chrysanthemum x morifolium Species 0.000 abstract 1
- 244000303040 Glycyrrhiza glabra Species 0.000 abstract 1
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 abstract 1
- 240000000691 Houttuynia cordata Species 0.000 abstract 1
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- 235000006679 Mentha X verticillata Nutrition 0.000 abstract 1
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- 244000124853 Perilla frutescens Species 0.000 abstract 1
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- UNNKKUDWEASWDN-UHFFFAOYSA-N alkannin Natural products CC(=CCC(O)c1cc(O)c2C(=O)C=CC(=O)c2c1O)C UNNKKUDWEASWDN-UHFFFAOYSA-N 0.000 abstract 1
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 abstract 1
- 229910052602 gypsum Inorganic materials 0.000 abstract 1
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- 235000011477 liquorice Nutrition 0.000 abstract 1
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- 241000700605 Viruses Species 0.000 description 5
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- 206010011224 Cough Diseases 0.000 description 2
- 241000709661 Enterovirus Species 0.000 description 2
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- 229940088710 antibiotic agent Drugs 0.000 description 1
- 239000002221 antipyretic Substances 0.000 description 1
- 239000003907 antipyretic analgesic agent Substances 0.000 description 1
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- 238000001802 infusion Methods 0.000 description 1
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- 231100000614 poison Toxicity 0.000 description 1
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- 241000701161 unidentified adenovirus Species 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention discloses a traditional Chinese medicine for treating viral influenza. The traditional Chinese medicine is characterized by being prepared from the following medicinal materials in parts by weight: 60 parts of gypsum, 150 parts of houttuynia cordata, 150 parts of platycodon grandiflorum, 60 parts of apricot kernel, 120 parts of chrysanthemum, 150 parts of mulberry leaf, 60 parts of herba schizonepetae, 90 parts of mint, 150 parts of rhizoma phragmitis, 150 parts of fructus forsythia, 90 parts of perilla leaf, 120 parts of rhizoma anemarrhenae, 150 parts of honeysuckle, 90 parts of scutellaria baicalensis, 120 parts of chinese mosla herb, 150 parts of root of kudzu vine, 90 parts of liuyi powder, 150 parts of folium isatidis, 120 parts of shikonin, 150 parts of radix isatidis and 60 parts of liquorice. The clinical test proves that the viral influenza can be safely and effectively treated.
Description
Technical field
The present invention relates to a kind of Chinese medicine, particularly a kind of herb mixture for the treatment of viral influenza and preparation method thereof.
Background technology
Viral influenza is the common a kind of diseases of people, comprises common cold, influenza and viral pharyngitis etc., mainly infects via nasal cavity by air or hands contact.Influenza is the Acute respiratory infectious disease being caused by influenza virus, and virus is present in patient's respiratory tract, in the time of patient cough, sneeze through droplet infection.Because its infectiousness is strong, route of transmission is wayward, spread speed is fast, spread scope is wide, therefore more difficult control, endangers very large.Common cold is to be caused by rhinovirus, coronavirus and parainfluenza virus etc., and common cold wants much weak compared with influenza infectiousness, often occurs individually, in the time that Abwehrkraft des Koepers declines, just easily ill.
Viral influenza is mainly the upper respiratory tract infection being caused by respiratory syncytial virus, rhinovirus, adenovirus, coronavirus and parainfluenza virus.The method for the treatment of viral influenza is mainly used antipyretic analgesic, antibiolics at present, seriously uses infusion treatment.Abuse of antibiotics, can cause dysbacteriosis, and body immunity is declined.
Summary of the invention
The problem to be solved in the present invention is: a kind of herb mixture for the treatment of viral influenza and preparation method thereof is provided, by selecting suitable medical material and proportioning thereof, reaches the object that safe and effective Cure Viruses sexuality is emitted.
In order to solve the problems of the technologies described above, the present invention by the following technical solutions:
A Chinese medicine for the treatment of viral influenza, is characterized in that, it is to be prepared into by the medical material of following parts by weight proportioning:
60 parts, Gypsum Fibrosum, 150 parts of Herba Houttuyniae, 150 parts of Radix Platycodoniss, 60 parts of Semen Armeniacae Amarums, 120 parts of Flos Chrysanthemis, 150 parts, Folium Mori, 60 parts of Herba Schizonepetae, 90 parts of Herba Menthaes, 150 parts of Rhizoma Phragmitiss, 150 parts of Fructus Forsythiaes, 90 parts of Folium Perillaes, 120 parts of the Rhizoma Anemarrhenaes, 150 parts of Flos Loniceraes, 90 parts of Radix Scutellariaes, 120 parts of Herba Moslaes, 150 parts of Radix Puerariaes, 90 parts of LIUYI SAN, 150 parts of Folium Isatidiss, 120 parts of Radix Arnebiae (Radix Lithospermi)s, 150 parts of Radix Isatidis, 60 parts, Radix Glycyrrhizae.
A preparation method for the herb mixture of above-mentioned treatment viral influenza, by above-mentioned raw materials medicine proportioning, comprises the following steps:
1) get Herba Houttuyniae, Herba Schizonepetae, Herba Menthae and add appropriate water, carry out vapor distillation, collect distillate for subsequent use;
2) medicinal liquid after extractive distillation liquid in step (1) is separated with medicinal residues, obtain the medicinal liquid after medicinal residues and extractive distillation liquid;
3) medicinal residues in step (2) are added to all the other 18 taste Chinese medicines, mix, add suitable quantity of water and decoct 2 times, each 2 hours, merge decoction liquor;
4) medicinal liquid after decoction liquor in step (3) and step (2) extractive distillation liquid is merged, filter, obtain filtering liquid medicine;
5) filtering liquid medicine in step (4) is concentrated into the clear paste that relative density is 1.10 (60 DEG C), adds ethanol and make medicinal liquid contain alcohol amount to reach 60%, leave standstill 24 hours;
6) by after concentrated in step (5) containing alcohol medical filtration, reclaim the ethanol in filtrate, and be concentrated into without alcohol taste;
7) concentrated medicament in step (6) is added to appropriate sucrose and sodium benzoate, boil, leave standstill 2 hours;
8) by the medical filtration after leaving standstill in step (7), add above-mentioned distillate, mix, filter, obtain antiviral herb mixture.
Below in conjunction with clinical experiment data declaration beneficial effect of the present invention:
1, general material
Inventor collects the out-patient that 280 examples have virus flu altogether, is divided at random: treatment group 150 examples, matched group 130 examples.The data such as two groups of sexes, age, the state of an illness there are no significant difference, has comparability.
2, test method
The oral common cold of matched group antibiotic medicine, is used to specifications.7 days courses for the treatment of.
The herb mixture of the viral influenza that the oral the present invention for the treatment of group makes according to specific embodiment, every bu is 2 clothes sooner or later
With.7 days courses for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
(1) recovery from illness: clinical symptoms and sign disappear completely or substantially disappear;
(2) effective: clinical symptoms and sign are most of to take a turn for the better or is clearly better;
(3) invalid; Clinical symptoms and sign are all not improved, and symptom is as front, DeGrain.
3.2 treatment statistical results are in table 1.
Table 1 liang group curative effect comparison
| Group | Case number | Recovery from illness | Effective | Invalid | Untoward reaction | Total effective rate % |
| Treatment group | 150 | 140 | 7 | 3 | 0(0％) | 98％ |
| Matched group | 130 | 25 | 54 | 51 | 0(0％) | 60.77％ |
Visible, the medicine that the preferred embodiment for the present invention makes can be treated viral influenza safely and effectively.
Detailed description of the invention
In order to understand better and to implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Specific embodiment
Take 60 grams, Gypsum Fibrosum, 150 grams of Herba Houttuyniae, 150 grams of Radix Platycodoniss, 60 grams of Semen Armeniacae Amarums, 120 grams of Flos Chrysanthemis, 150 grams, Folium Mori, 60 grams of Herba Schizonepetae, 90 grams of Herba Menthaes, 150 grams of Rhizoma Phragmitiss, 150 grams of Fructus Forsythiaes, 90 grams of Folium Perillaes, 120 grams of the Rhizoma Anemarrhenaes, 150 grams of Flos Loniceraes, 90 grams of Radix Scutellariaes, 120 grams of Herba Moslaes, 150 grams of Radix Puerariaes, 90 grams of LIUYI SAN, 150 grams of Folium Isatidiss, 120 grams of Radix Arnebiae (Radix Lithospermi)s, 150 grams of Radix Isatidis, 60 grams, Radix Glycyrrhizae.The first step, gets 90 grams of 150 grams of Herba Houttuyniae, 60 grams of Herba Schizonepetae, Herba Menthae and adds appropriate water, carries out vapor distillation, collects distillate for subsequent use; Second step separates the medicinal liquid after extractive distillation liquid in the first step with medicinal residues, obtain the medicinal liquid after medicinal residues and extractive distillation liquid; The medicinal residues in second step are added 60 grams, Gypsum Fibrosum, 150 grams of Radix Platycodoniss, 60 grams of Semen Armeniacae Amarums, 120 grams of Flos Chrysanthemis, 150 grams, Folium Mori, 150 grams of Rhizoma Phragmitiss, 150 grams of Fructus Forsythiaes, 90 grams of Folium Perillaes, 120 grams of the Rhizoma Anemarrhenaes, 150 grams of Flos Loniceraes, 90 grams of Radix Scutellariaes, 120 grams of Herba Moslaes, 150 grams of Radix Puerariaes, 90 grams of LIUYI SAN, 150 grams of Folium Isatidiss, 120 grams of Radix Arnebiae (Radix Lithospermi)s, 150 grams of Radix Isatidis, 60 grams, Radix Glycyrrhizae by the 3rd step, mix, adding suitable quantity of water decocts 2 times, each 2 hours, merge decoction liquor; The 4th step merges the medicinal liquid after extractive distillation liquid in decoction liquor and second step in the 3rd step, filters, and obtains filtering liquid medicine; The filtering liquid medicine in the 4th step is concentrated into the clear paste that relative density is 1.10 (60 DEG C) by the 5th step, adds ethanol and make medicinal liquid contain alcohol amount to reach 60%, leaves standstill 24 hours; The 6th step by after concentrated in the 5th step containing alcohol medical filtration, reclaim the ethanol in filtrate, and be concentrated into without alcohol taste; Concentrated medicament in the 6th step is added appropriate sucrose and sodium benzoate by the 7th step, boils, and leaves standstill 2 hours; The 8th step, by the medical filtration after leaving standstill in the 7th step, adds above-mentioned distillate, mixes, and filters, and obtains antiviral herb mixture.
Function with cure mainly: heat-clearing and toxic substances removing, removing heat from blood sore-throat relieving, anti-inflammatory antipyretic.For viral infection diseases such as viral influenza, upper respiratory tract infection, influenza, parotitis, tonsillitiss.Mainly contain the diseases such as headache, heating, watery nasal discharge, laryngopharynx swelling and pain, cough.
Usage and dosage: oral, the 10-20ml that is grown up a time, 3 times on the one; Below 3 one full year of life of children's, a 5ml, 3-7 one full year of life, a 5-10ml, 3 times on the one.
Facts have proved through a large amount of clinical treatments, the present invention treats the herb mixture of viral influenza, belong to pure Chinese medicinal preparation, little to human body toxicity, side effect, to all kinds of viral infection diseases such as treatment viral influenza, upper respiratory tract infection, influenza, parotitis, tonsillitiss, there is reliable, safe, significant therapeutic effect.
Claims (2)
1. treat the herb mixture of viral influenza for one kind, it is characterized in that, it is to be prepared into by the medical material of following parts by weight proportioning: 60 parts, Gypsum Fibrosum, 150 parts of Herba Houttuyniae, 150 parts of Radix Platycodoniss, 60 parts of Semen Armeniacae Amarums, 120 parts of Flos Chrysanthemis, 150 parts, Folium Mori, 60 parts of Herba Schizonepetae, 90 parts of Herba Menthaes, 150 parts of Rhizoma Phragmitiss, 150 parts of Fructus Forsythiaes, 90 parts of Folium Perillaes, 120 parts of the Rhizoma Anemarrhenaes, 150 parts of Flos Loniceraes, 90 parts of Radix Scutellariaes, 120 parts of Herba Moslaes, 150 parts of Radix Puerariaes, 90 parts of LIUYI SAN, 150 parts of Folium Isatidiss, 120 parts of Radix Arnebiae (Radix Lithospermi)s, 150 parts of Radix Isatidis, 60 parts, Radix Glycyrrhizae.
2. the preparation method of the herb mixture for the treatment of viral influenza according to claim 1, is characterized in that: comprise the following steps:
1) get Herba Houttuyniae, Herba Schizonepetae, Herba Menthae and add appropriate water, carry out vapor distillation, collect distillate for subsequent use;
2) medicinal liquid after extractive distillation liquid in step (1) is separated with medicinal residues, obtain the medicinal liquid after medicinal residues and extractive distillation liquid;
3) medicinal residues in step (2) are added to all the other 18 taste Chinese medicines, mix, add suitable quantity of water and decoct 2 times, each 2 hours, merge decoction liquor;
4) medicinal liquid after decoction liquor in step (3) and step (2) extractive distillation liquid is merged, filter, obtain filtering liquid medicine;
5) filtering liquid medicine in step (4) is concentrated into the clear paste that relative density is 1.10 (60 DEG C), adds ethanol and make medicinal liquid contain alcohol amount to reach 60%, leave standstill 24 hours;
6) by after concentrated in step (5) containing alcohol medical filtration, reclaim the ethanol in filtrate, and be concentrated into without alcohol taste;
7) concentrated medicament in step (6) is added to appropriate sucrose and sodium benzoate, boil, leave standstill 2 hours;
8) by the medical filtration after leaving standstill in step (7), add above-mentioned distillate, mix, filter, obtain antiviral herb mixture.
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103550352A (en) * | 2013-10-30 | 2014-02-05 | 潘昌仁 | Traditional Chinese medicine for treating influenza |
| CN104940628A (en) * | 2015-06-23 | 2015-09-30 | 张光辉 | Traditional Chinese medicine composition capable of preventing flu and preparation method |
| CN107375749A (en) * | 2017-08-04 | 2017-11-24 | 陕西必康制药集团控股有限公司 | A kind of folium isatidis mixture and preparation method thereof |
| CN107441383A (en) * | 2015-10-16 | 2017-12-08 | 天圣制药集团股份有限公司 | One kind is used for clearing away heat for children inducing diaphoresis prescription medicine, preparation method and applications |
| CN107469034A (en) * | 2017-08-16 | 2017-12-15 | 河南中医药大学 | A kind of Chinese medicine for treating virus flu |
| CN107596096A (en) * | 2017-10-27 | 2018-01-19 | 杨小丽 | A kind of medicine for treating influenza and preparation method thereof |
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| CN1418688A (en) * | 2002-11-29 | 2003-05-21 | 张慧芳 | Medicine composition for treating cold and cough, and its prepn. method |
| CN1927351A (en) * | 2005-09-06 | 2007-03-14 | 武涛 | Heat clearing and detoxicating drug for abating fever |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103550352A (en) * | 2013-10-30 | 2014-02-05 | 潘昌仁 | Traditional Chinese medicine for treating influenza |
| CN103550352B (en) * | 2013-10-30 | 2015-05-06 | 潘昌仁 | Traditional Chinese medicine for treating influenza |
| CN104940628A (en) * | 2015-06-23 | 2015-09-30 | 张光辉 | Traditional Chinese medicine composition capable of preventing flu and preparation method |
| CN107441383A (en) * | 2015-10-16 | 2017-12-08 | 天圣制药集团股份有限公司 | One kind is used for clearing away heat for children inducing diaphoresis prescription medicine, preparation method and applications |
| CN107375749A (en) * | 2017-08-04 | 2017-11-24 | 陕西必康制药集团控股有限公司 | A kind of folium isatidis mixture and preparation method thereof |
| CN107469034A (en) * | 2017-08-16 | 2017-12-15 | 河南中医药大学 | A kind of Chinese medicine for treating virus flu |
| CN107596096A (en) * | 2017-10-27 | 2018-01-19 | 杨小丽 | A kind of medicine for treating influenza and preparation method thereof |
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