Summary of the invention
The invention provides a kind of health food with health slimming effect, according to the traditional Chinese medical science, fat cognition is carried out to formula Design with conditioning principle.
Described a kind of health food with health slimming effect, is made up of the raw material of following weight proportion: gynostemma pentaphylla 11-65 part, hawthorn 4-25 part, fruit of Chinese wolfberry 3-18 part, cassia seed 3-15 part, RADIX POLYGONI MULTIFLORI PREPARATA 2-13 part, bighead atractylodes rhizome 2-13 part, citron 2-12 part, red sage root 2-10 part, orange peel 1-8 part.
The described health food with health slimming effect is preferably made up of the raw material of following weight proportion:
Gynostemma pentaphylla 18-54 part, hawthorn 7-21 part, fruit of Chinese wolfberry 5-15 part, cassia seed 4-13 part, RADIX POLYGONI MULTIFLORI PREPARATA 4-11 part, bighead atractylodes rhizome 4-11 part, citron 3-10 part, red sage root 3-8 part, orange peel 2-7 part.
Described a kind of health food with health slimming effect is further preferably made up of the raw material of following weight proportion:
Gynostemma pentaphylla 29-44 part, hawthorn 11-17 part, fruit of Chinese wolfberry 8-12 part, cassia seed 7-10 part, RADIX POLYGONI MULTIFLORI PREPARATA 6-9 part, bighead atractylodes rhizome 6-9 part, citron 5-8 part, red sage root 4-7 part, orange peel 4-6 part.
Be appreciated that health food of the present invention also comprises appropriate amount of auxiliary materials, described auxiliary material meets health food laws and regulations requirement.
Described part is the unit of weights such as g, kg, ton.
Described raw material can, by adopting ultrasonic wave assisted extraction, concentrate, and/or spraying is dry, adds health food regulation to allow the auxiliary material using, and is prepared into the formulations such as bag tea agent, tablet, capsule, granule.
The described health food dose with health slimming effect is recommended as, every day 2-3 time; Tea in bag formulation is 2-5g/ time, and tablet or capsule formulation are 1-3g/ time, and granule formulation is 2-6g/ time.
The described health food with health slimming effect, can adopt the method preparation of the following step:
1) take the raw material of following weight proportion:
Gynostemma pentaphylla 11-65 part, hawthorn 4-25 part, fruit of Chinese wolfberry 3-18 part, cassia seed 3-15 part, RADIX POLYGONI MULTIFLORI PREPARATA 2-13 part, bighead atractylodes rhizome 2-13 part, citron 2-12 part, red sage root 2-10 part, orange peel 1-8 part;
2) above-mentioned raw materials is adopted ultrasonic wave assisted Extraction follow the example of, extract its effective ingredient, and to adopt Vacuum Concentration method to make density be 1.05-1.3g/cm
3concentrate;
Described ultrasonic wave assisted Extraction is followed the example of to be preferably and is adopted the pure water of 40 DEG C-70 DEG C to soak 1-3 hour above-mentioned raw materials, and insulation, adopts 300-1000W ultrasonic wave, carries out 2 times and extracts, and extracts amount of water for the 1st time and be the 5-10 of medicinal material weight doubly, extraction time 20-60min; Extract amount of water for the 2nd time and be the 3-5 of medicinal material weight doubly, extraction time 10-50min; No. 2 extracts are merged, adopt 200 orders to filter; Via Vacuum Concentration, making density is 1.05-1.30g/cm again
3concentrate;
3) taking gained concentrate as primary raw material, add health food regulation to allow the auxiliary material using, be prepared into the formulations such as bag tea agent, capsule, tablet, granule;
Or the spraying of gained concentrate is dried and makes former medicine dry powder; Taking the former medicine dry powder of gained as primary raw material, add health food regulation to allow the auxiliary material using, be prepared into the formulations such as bag tea agent, capsule, tablet, granule.
The described health food with health slimming effect, also can adopt the method preparation of the following step:
1) take the raw material of following weight proportion:
Gynostemma pentaphylla 11-65 part, hawthorn 4-25 part, fruit of Chinese wolfberry 3-18 part, cassia seed 3-15 part, RADIX POLYGONI MULTIFLORI PREPARATA 2-13 part, bighead atractylodes rhizome 2-13 part, citron 2-12 part, red sage root 2-10 part, orange peel 1-8 part.
2) hawthorn, the fruit of Chinese wolfberry, cassia seed, RADIX POLYGONI MULTIFLORI PREPARATA, the bighead atractylodes rhizome, citron, the red sage root, orange peel are mixed, adopt the conventional water extraction method of modern Chinese herbal medicine, extract its effective ingredient, and to adopt Vacuum Concentration method to make density be 1.05-1.30g/cm
3concentrate;
Preferably hawthorn, the fruit of Chinese wolfberry, cassia seed, RADIX POLYGONI MULTIFLORI PREPARATA, the bighead atractylodes rhizome, citron, the red sage root, orange peel are mixed, adopt the pure water of 40 DEG C-70 DEG C to soak 1-3 hour above-mentioned raw materials, insulation, adopt 300-1000W ultrasonic wave, carrying out 2 times extracts, extract amount of water for the 1st time and be the 5-10 of medicinal material weight doubly, extraction time 20-60min; Extract amount of water for the 2nd time and be the 3-5 of medicinal material weight doubly, extraction time 10-50min; No. 2 extracts are merged, adopt 200 orders to filter; Via Vacuum Concentration, making density is 1.05-1.30g/cm again
3concentrate;
3) gained concentrate is mixed with gynostemma pentaphylla, and infiltrate 30-60 minute, allow gynostemma pentaphylla that concentrate is fully absorbed, then adopt oven drying method or fluid-bed drying, be dried to moisture≤8%, after packaging, make tea in bag.
The traditional Chinese medical science thinks that obesity mostly is the disease of asthenia in origin and asthenia in superficiality, and mark is real to be shown as: wet, phlegm, the stasis of blood are main, and this void shows as: weakness of the spleen and the stomach, liver dysfunction is main.Therefore, for fat conditioning should be with dampness elimination, eliminate the phlegm, stagnation resolvation, invigorating the spleen, treatment for relieving indigestion and constipation, Wen Yangwei master.The present invention is taking theory of traditional Chinese medical science as guidance, according to the traditional Chinese medical science to fat cognition and conditioning principle, the food and medicament dual-purpose Chinese medicines such as selected gynostemma pentaphylla, hawthorn, the fruit of Chinese wolfberry, cassia seed, RADIX POLYGONI MULTIFLORI PREPARATA, the bighead atractylodes rhizome, citron, the red sage root, orange peel, adopt modern crafts to prepare the health food with health slimming effect.
Gynostemma pentaphylla, bitter, micro-sweet, cool in nature; Return lung, spleen, kidney channel.Effect: replenish qi to invigorate the spleen, preventing phlegm from forming and stopping coughing, clearing heat and detoxicating.The main active ingredient of gynostemma pentaphylla is polysaccharide, flavonoids, saponins and microelement kind, has the body fat of promotion class metabolism, nutrition human body cell, has good detoxicating, relieving inflammation effect simultaneously.
Hawthorn, taste acid is sweet, slightly warm in nature; Enter spleen, stomach, Liver Channel.There is food digesting stomach fortifying, activate blood circulation and disperse blood clots, restrain the only function of dysentery.Because hawthorn is containing the multiple organic acid such as crataegolic acid, taste acid is sweet, and containing lipolytic enzyme, enters after stomach, can strengthen the effect of enzyme, promotes carnivorous digestion, contributes to cholesterol to transform, and hawthorn also can cholagogic juice, promotes gastric secretion.
The fruit of Chinese wolfberry, taste is sweet, and property is flat; Return liver, kidney, lung channel.Effect: nourishing liver and kidney, benefiting shrewd head.The fruit of Chinese wolfberry has the effect of the kidney tonifying of protecting the liver, and can suppress fat and deposit in liver cell, and promote hepatocellular new life.
Cassia seed, mildly bitter flavor is micro-sweet, and property is flat, micro-cool; Return liver, kidney, large intestine channel.Effect: removing heat to brighten vision, relax bowel, there is effect of fat-reducing.
RADIX POLYGONI MULTIFLORI PREPARATA, bitter, sweet, puckery, tepor; Return liver, the heart, kidney channel.Effect: filling liver kidney, benefiting essence-blood, black beard and hair, strengthening the bones and muscles, changes turbid lipopenicillinase.
The bighead atractylodes rhizome, bitter, sweet, warm in nature; Return spleen, stomach warp.Effect: air making-up and spleen enlivening, eliminating dampness Li Shui.
Citron, pungent, the micro-hardship of taste, acid, warm in nature; Return liver, lung, the spleen channel.Effect: the fragrant row of gas is loose, can rise and can fall; Have dispersing stagnated hepatoqi, wide chest reduces phlegm, dehumidifying and in.
The red sage root, bitter, gas is slightly cold, nontoxic; Enter the heart, spleen two warps.Root is used as medicine, and containing tanshinone, has the effectiveness such as promoting blood circulation and removing blood stasis, regulating qi-flowing for relieving pain.
Orange peel, taste is pungent, warm in nature, nontoxic; Enter lung, liver, spleen, stomach four warps.Effect: regulate the flow of vital energy, in tune, eliminating dampness, reduces phlegm.This product eliminating dampness and can spleen benefiting and stimulating the appetite, is applicable to the diseases such as weakness of the spleen and the stomach, diet minimizing, indigestion, stool diarrhea.
Wherein, gynostemma pentaphylla replenishes qi to invigorate the spleen, eliminating phlegm stagnation resolvation, and fat eliminating is fallen turbid; Hawthorn digesting eliminate indigestion, the promoting the circulation of qi stasis of blood of faling apart, this two taste is monarch, can play and replenish qi to invigorate the spleen, the eliminating phlegm stasis of blood of faling apart, esterified long-pending effect disappears.Fruit of Chinese wolfberry nourishing YIN for benefiting the kidney, cassia seed heat-clearing, ease constipation, defaecation, RADIX POLYGONI MULTIFLORI PREPARATA tonifies the liver and kidney, removing toxic substances ease constipation, this three taste is minister, the yin asthenia generating intrinsic heat effect that obesity is caused is remarkable, with the effect of auxiliary monarch drug in a prescription.Bighead atractylodes rhizome strengthening the spleen and replenishing qi, eliminating dampness Li Shui, citron liver-smoothing, qi-regulating, reduces phlegm in wide, and the red sage root is promoting blood circulation and removing blood stasis, lowering fat to dredge vessels, enriching yin boost qi, this three taste, for assistant, assistant helps group minister, makes its effect more remarkable.Orange peel regulating qi-flowing for strengthening spleen, eliminating dampness and eliminating phlegm, its character gentleness, returns spleen, lung channel, for making, reaches its sick institute with all medicines in the side of drawing, and its contained orange peel volatile oil can promote the discharge of gastric secretion and gastrointestinal pneumatosis, helps digestion.
The present invention's formula is on the basis of traditional chinese medicine, carries out compatibility design in conjunction with modern medicine study achievement, for the feature of obesity, and treatment of deficiency-syndrome by reinforcement, excess syndrome should be treated with purgation, taking strengthening the spleen and replenishing qi as benefit, the water of dispelling is wet, and the stasis of blood of dispelling is stagnant; With dispelling dampness and promoting diuresis, logical internal organs treatment for relieving indigestion and constipation is for rushing down, and dispels and in body, stops the turbid and unnecessary cream fat that wets that gathers.All medicines are associated with, and make the medicine performance comprehensive function of each tool characteristic, according to tcm treatment according to syndrome differentiation theory, obesity are had to good antiobesity action.The prepared product of processing method that adopts this proportion design and the present invention to list, through clinical test-meal verification experimental verification, the present invention has health slimming health-care effect.
Detailed description of the invention
Embodiment 1
1, take the raw material of following weight proportion:
Gynostemma pentaphylla 12kg, hawthorn 4kg, fruit of Chinese wolfberry 4kg, cassia seed 3kg, RADIX POLYGONI MULTIFLORI PREPARATA 2kg, bighead atractylodes rhizome 2kg, citron 2kg, red sage root 2kg, orange peel 1kg;
2, above-mentioned raw materials is adopted the pure water of 50 DEG C soak 2 hours, insulation, adopts 500W ultrasonic wave, carries out 2 times and extracts, and extract amount of water for the 1st time and be medicinal material weight 10 times, extraction time 40min; The 2nd time is extracted amount of water is 5 times of medicinal material weight, extraction time 30min; No. 2 extracts are merged, adopt 200 orders to filter; Via Vacuum Concentration, making density is 1.15g/cm again
3concentrate;
3, former medicine dry powder will be made after spray-dried the concentrate of gained; Former medicine dry powder is added to the dextrin of equivalent, make according to a conventional method capsule product.Capsule grain is heavily 0.75g/ grain.
Embodiment 2
1, take the raw material of following weight proportion:
Gynostemma pentaphylla 180g, hawthorn 70g, fruit of Chinese wolfberry 50g, cassia seed 50g, RADIX POLYGONI MULTIFLORI PREPARATA 40g, bighead atractylodes rhizome 40g, citron 40g, red sage root 30g, orange peel 20g;
2, above-mentioned raw materials is adopted the pure water of 60 DEG C soak 1.5 hours, insulation, adopts 400W ultrasonic wave, carries out 2 times and extracts, and extract amount of water for the 1st time and be medicinal material weight 8 times, extraction time 60min; The 2nd time is extracted amount of water is 4 times of medicinal material weight, extraction time 20min; No. 2 extracts are merged, adopt 200 orders to filter; Via Vacuum Concentration, making density is 1.1g/cm again
3concentrate;
3, former medicine dry powder will be made after spray-dried gained concentrate; Former medicine dry powder is added to the dextrin of equivalent, make according to a conventional method capsule product.Capsule grain is heavily 0.5g/ grain.
Embodiment 3
1, take the raw material of following weight proportion:
29 parts of gynostemma pentaphylla, 11 parts of hawthorn, 8 parts of the fruits of Chinese wolfberry, 7 parts of cassia seeds, 7 parts of RADIX POLYGONI MULTIFLORI PREPARATAs, 6 parts of the bighead atractylodes rhizomes, 6 parts of citrons, 5 parts of the reds sage root, 3 parts of orange peels;
2, above-mentioned raw materials is adopted the pure water of 70 DEG C soak 1.0 hours, insulation, adopts 300W ultrasonic wave, carries out 2 times and extracts, and extract amount of water for the 1st time and be medicinal material weight 5 times, extraction time 20min; The 2nd time is extracted amount of water is 3 times of medicinal material weight, extraction time 40min; No. 2 extracts are merged, adopt 200 orders to filter; Via Vacuum Concentration, making density is 1.2g/cm again
3concentrate;
3, former medicine dry powder will be made after spray-dried gained concentrate; Former medicine dry powder is added to the dextrin of equivalent and the sweet mellow wine of equivalent, according to a conventional method granulation agent goods.
Embodiment 4
1, take the raw material of following weight proportion:
43 parts of gynostemma pentaphylla, 17 parts of hawthorn, 12 parts of the fruits of Chinese wolfberry, 11 parts of cassia seeds, 9 parts of RADIX POLYGONI MULTIFLORI PREPARATAs, 9 parts of the bighead atractylodes rhizomes, 8 parts of citrons, 7 parts of the reds sage root, 6 parts of orange peels;
2, above-mentioned raw materials is adopted the pure water of 40 DEG C soak 3 hours, insulation, adopts 1000W ultrasonic wave, carries out 2 times and extracts, and extract amount of water for the 1st time and be medicinal material weight 6 times, extraction time 60min; The 2nd time is extracted amount of water is 4 times of medicinal material weight, extraction time 10min; No. 2 extracts are merged, adopt 200 orders to filter; Via Vacuum Concentration, making density is 1.25g/cm again
3concentrate;
3, be primary raw material by gained concentrate, taking 360 parts of dextrin as auxiliary material, make according to a conventional method tablet product.
Embodiment 5
1, take the raw material of following weight proportion:
65 parts of gynostemma pentaphylla, 25 parts of hawthorn, 17 parts of the fruits of Chinese wolfberry, 15 parts of cassia seeds, 13 parts of RADIX POLYGONI MULTIFLORI PREPARATAs, 13 parts of the bighead atractylodes rhizomes, 12 parts of citrons, 10 parts of the reds sage root, 8 parts of orange peels;
2, hawthorn, the fruit of Chinese wolfberry, cassia seed, RADIX POLYGONI MULTIFLORI PREPARATA, the bighead atractylodes rhizome, citron, the red sage root, orange peel are mixed, raw material adopts the pure water of 55 DEG C to soak 2 hours, insulation, adopt 550W ultrasonic wave, carry out 2 times and extract, the 1st time is extracted amount of water is 9 times of medicinal material weight, extraction time 40min; The 2nd time is extracted amount of water is 4 times of medicinal material weight, extraction time 30min; No. 2 extracts are merged, adopt 200 orders to filter; Via Vacuum Concentration, making density is 1.05g/cm again
3concentrate;
3, gained concentrate is mixed with gynostemma pentaphylla (65 parts), and infiltrate 30-60 minute, allow gynostemma pentaphylla that concentrate is fully absorbed, then adopt oven drying method or fluid-bed drying, be dried to moisture≤8%, after packaging, make tea in bag.
Product health care of the present invention clinical testing
1, test crowd: choose 120 simple obesity adults, in age 18-65 year, men and women half and half.
2, experimental design: be divided at random test-meal group and control group by experimenter's body weight, body fat weight, every group of 60 people.Remove and end for some reason experimenter, actual test-meal group 53 people, control group 52 people midway.Adopt between own control and group and contrast.
3, test method: test-meal group is taken the prepared capsule of the embodiment of the present invention 2, takes 3 every day, each 3 (0.5g/ grain).Control group is taken capsule placebo, takes each 3 (0.5g/ grain, every fill is 0.45g dextrin and 0.05g Tea Polyphenols) every day 3 times.Test period is 35 days, and two groups of crowd's duration of test are eaten the high confectionery thing of high fat less.
4, functional observation: measure comparison test-meal front and back body weight, body fat total amount and fatty percentage.
5, result of the test: in table 1 and table 2.
Experimenter's body weight, body fat, Rate of body lipid situation of change before and after table 1 test-meal
Experimenter's security inspection result before and after table 2 test-meal
Before note: * and test-meal, compare P < 0.01
Edible sample of the present invention is after 35 days continuously for test-meal group, and body weight, body fat total amount, Rate of body lipid significantly decline; Weight average decline 2.7kg, total amount of body fat decline 2.4kg, Rate of body lipid on average declines 1.4%.Meanwhile, the triglycerides before the test-meal of test-meal group and before and after control group test-meal is all a little more than normal value, and test-meal group is recovered in range of normal value after test-meal; The routine blood test of experimenter before and after testing, blood biochemical indices, uric acid, heart rate etc. are all in range of normal value; And the equal no exceptions of item inspection such as electrocardiogram, Chest X-rays, B ultrasonic.
6, conclusion: test shows above, and sample of the present invention has obvious antiobesity action to human body.In fat-reducing, human body indices all keeps stablizing and in range of normal value, shows that the present invention not only has antiobesity action, but also can ensure the health of human body in fat-reducing process.