CN103948875A - Medicine for treating hepatitis B and preparation method thereof - Google Patents
Medicine for treating hepatitis B and preparation method thereof Download PDFInfo
- Publication number
- CN103948875A CN103948875A CN201410200135.2A CN201410200135A CN103948875A CN 103948875 A CN103948875 A CN 103948875A CN 201410200135 A CN201410200135 A CN 201410200135A CN 103948875 A CN103948875 A CN 103948875A
- Authority
- CN
- China
- Prior art keywords
- radix
- parts
- medicine
- semen
- hepatitis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 title claims abstract description 84
- 229940079593 drug Drugs 0.000 title claims abstract description 44
- 208000002672 hepatitis B Diseases 0.000 title claims abstract description 30
- 238000002360 preparation method Methods 0.000 title claims abstract description 23
- 239000010135 fructus aurantii immaturus Substances 0.000 claims abstract description 11
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 claims abstract description 9
- 244000080767 Areca catechu Species 0.000 claims abstract 2
- 244000179560 Prunella vulgaris Species 0.000 claims abstract 2
- 210000000582 semen Anatomy 0.000 claims description 76
- 241000628997 Flos Species 0.000 claims description 19
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 17
- 239000009636 Huang Qi Substances 0.000 claims description 11
- 235000014375 Curcuma Nutrition 0.000 claims description 10
- 241001529553 Scoparia <angiosperm> Species 0.000 claims description 10
- 241001530126 Scrophularia Species 0.000 claims description 10
- 241000545442 Radix Species 0.000 claims description 8
- 239000000284 extract Substances 0.000 claims description 5
- 239000007788 liquid Substances 0.000 claims description 5
- 239000011550 stock solution Substances 0.000 claims description 2
- 244000164439 Curcuma angustifolia Species 0.000 claims 1
- 239000012153 distilled water Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 10
- 210000004185 liver Anatomy 0.000 abstract description 4
- 230000003750 conditioning effect Effects 0.000 abstract description 3
- 210000001835 viscera Anatomy 0.000 abstract description 2
- 240000006995 Abutilon theophrasti Species 0.000 abstract 1
- 241001633574 Adenophora stricta Species 0.000 abstract 1
- 235000009051 Ambrosia paniculata var. peruviana Nutrition 0.000 abstract 1
- 244000144725 Amygdalus communis Species 0.000 abstract 1
- 235000011437 Amygdalus communis Nutrition 0.000 abstract 1
- 235000006226 Areca catechu Nutrition 0.000 abstract 1
- 235000003097 Artemisia absinthium Nutrition 0.000 abstract 1
- 240000001851 Artemisia dracunculus Species 0.000 abstract 1
- 235000017731 Artemisia dracunculus ssp. dracunculus Nutrition 0.000 abstract 1
- 235000003261 Artemisia vulgaris Nutrition 0.000 abstract 1
- 241000045403 Astragalus propinquus Species 0.000 abstract 1
- 244000164480 Curcuma aromatica Species 0.000 abstract 1
- 235000003398 Curcuma aromatica Nutrition 0.000 abstract 1
- 244000303040 Glycyrrhiza glabra Species 0.000 abstract 1
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 abstract 1
- 241000209035 Ilex Species 0.000 abstract 1
- 235000003332 Ilex aquifolium Nutrition 0.000 abstract 1
- 235000002296 Ilex sandwicensis Nutrition 0.000 abstract 1
- 235000002294 Ilex volkensiana Nutrition 0.000 abstract 1
- 240000000249 Morus alba Species 0.000 abstract 1
- 235000008708 Morus alba Nutrition 0.000 abstract 1
- 241001079007 Phellodendron chinense Species 0.000 abstract 1
- 241000304195 Salvia miltiorrhiza Species 0.000 abstract 1
- 235000011135 Salvia miltiorrhiza Nutrition 0.000 abstract 1
- 241000219784 Sophora Species 0.000 abstract 1
- 235000020224 almond Nutrition 0.000 abstract 1
- 239000001138 artemisia absinthium Substances 0.000 abstract 1
- 235000006533 astragalus Nutrition 0.000 abstract 1
- 235000013399 edible fruits Nutrition 0.000 abstract 1
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 abstract 1
- 235000011477 liquorice Nutrition 0.000 abstract 1
- 235000008113 selfheal Nutrition 0.000 abstract 1
- KDYFGRWQOYBRFD-UHFFFAOYSA-N succinic acid Chemical compound OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
- 230000002421 anti-septic effect Effects 0.000 description 10
- 239000012567 medical material Substances 0.000 description 10
- 241000407170 Curcuma Species 0.000 description 9
- 238000009835 boiling Methods 0.000 description 9
- 238000001914 filtration Methods 0.000 description 9
- 239000000843 powder Substances 0.000 description 9
- 230000001737 promoting effect Effects 0.000 description 9
- 241000202755 Areca Species 0.000 description 8
- 241001529739 Prunella <angiosperm> Species 0.000 description 8
- 239000000203 mixture Substances 0.000 description 8
- 238000001556 precipitation Methods 0.000 description 8
- 241000700721 Hepatitis B virus Species 0.000 description 4
- 241000700605 Viruses Species 0.000 description 4
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 description 4
- 239000008280 blood Substances 0.000 description 4
- 210000004369 blood Anatomy 0.000 description 4
- 238000002560 therapeutic procedure Methods 0.000 description 4
- 208000017667 Chronic Disease Diseases 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 3
- 206010062717 Increased upper airway secretion Diseases 0.000 description 3
- 230000004087 circulation Effects 0.000 description 3
- 230000002443 hepatoprotective effect Effects 0.000 description 3
- 210000000936 intestine Anatomy 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 244000052769 pathogen Species 0.000 description 3
- 230000001717 pathogenic effect Effects 0.000 description 3
- 208000026435 phlegm Diseases 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- 239000005711 Benzoic acid Substances 0.000 description 2
- 206010011224 Cough Diseases 0.000 description 2
- 241000721047 Danaus plexippus Species 0.000 description 2
- 208000000857 Hepatic Insufficiency Diseases 0.000 description 2
- 206010019663 Hepatic failure Diseases 0.000 description 2
- 208000002193 Pain Diseases 0.000 description 2
- 208000004880 Polyuria Diseases 0.000 description 2
- 230000002159 abnormal effect Effects 0.000 description 2
- 235000010233 benzoic acid Nutrition 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 210000001124 body fluid Anatomy 0.000 description 2
- 239000010839 body fluid Substances 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 230000035619 diuresis Effects 0.000 description 2
- 239000002934 diuretic Substances 0.000 description 2
- 230000001882 diuretic effect Effects 0.000 description 2
- 230000000857 drug effect Effects 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 241000411851 herbal medicine Species 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 230000003908 liver function Effects 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 230000001662 opsonic effect Effects 0.000 description 2
- 210000000056 organ Anatomy 0.000 description 2
- 230000036407 pain Effects 0.000 description 2
- 231100000614 poison Toxicity 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 238000010926 purge Methods 0.000 description 2
- 210000000952 spleen Anatomy 0.000 description 2
- 239000003440 toxic substance Substances 0.000 description 2
- 206010010774 Constipation Diseases 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 206010019842 Hepatomegaly Diseases 0.000 description 1
- 206010023126 Jaundice Diseases 0.000 description 1
- 206010067482 No adverse event Diseases 0.000 description 1
- 244000131316 Panax pseudoginseng Species 0.000 description 1
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 description 1
- 235000003140 Panax quinquefolius Nutrition 0.000 description 1
- 206010037660 Pyrexia Diseases 0.000 description 1
- 206010040943 Skin Ulcer Diseases 0.000 description 1
- 102000003929 Transaminases Human genes 0.000 description 1
- 108090000340 Transaminases Proteins 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 239000012670 alkaline solution Substances 0.000 description 1
- 230000000840 anti-viral effect Effects 0.000 description 1
- 230000036528 appetite Effects 0.000 description 1
- 235000019789 appetite Nutrition 0.000 description 1
- 230000004596 appetite loss Effects 0.000 description 1
- 230000001174 ascending effect Effects 0.000 description 1
- 208000019425 cirrhosis of liver Diseases 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000002651 drug therapy Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 230000004438 eyesight Effects 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 235000008434 ginseng Nutrition 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- 230000023597 hemostasis Effects 0.000 description 1
- 230000002440 hepatic effect Effects 0.000 description 1
- 208000006454 hepatitis Diseases 0.000 description 1
- 231100000283 hepatitis Toxicity 0.000 description 1
- 210000003494 hepatocyte Anatomy 0.000 description 1
- 230000007365 immunoregulation Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 235000021266 loss of appetite Nutrition 0.000 description 1
- 208000019017 loss of appetite Diseases 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 230000002175 menstrual effect Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000000306 recurrent effect Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 231100000019 skin ulcer Toxicity 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 230000002936 tranquilizing effect Effects 0.000 description 1
- UJMBCXLDXJUMFB-UHFFFAOYSA-K trisodium;5-oxo-1-(4-sulfonatophenyl)-4-[(4-sulfonatophenyl)diazenyl]-4h-pyrazole-3-carboxylate Chemical group [Na+].[Na+].[Na+].[O-]C(=O)C1=NN(C=2C=CC(=CC=2)S([O-])(=O)=O)C(=O)C1N=NC1=CC=C(S([O-])(=O)=O)C=C1 UJMBCXLDXJUMFB-UHFFFAOYSA-K 0.000 description 1
- 210000004916 vomit Anatomy 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to the field of medicines, and in particular relates to a medicine for treating hepatitis B and a preparation method thereof. The medicine for treating hepatitis B is prepared from the following raw medicines in parts by weight: radix bupleuri, radix paeoniae alba, salvia miltiorrhiza, betel nut, fructus aurantii immaturus, rhizoma alismatis, chingma abutilon seed, adenophora stricta, platycladi seed, almond, radix scrophulariae, astragalus membranaceus, oriental wormwood, mulberry fruit, radix peucedani, curcuma aromatica, phellodendron chinense schneid, selfheal, holly root, radix rehmanniae, subprostrate sophora and liquorice. The pure traditional Chinese medicine for treating hepatitis B does not cause any toxic and side effects, is stable in treatment effect, combines the treatment and conditioning, and can protect liver; the medicine prepared by the preparation method for treating hepatitis B has the advantages that the formula is suitable for all people, and the treatment effect is stable; in addition, the medicine has the conditioning function during treating, enables interfunctional coordination of the viscera, and is capable of protecting the liver.
Description
Technical field
The present invention relates to field of medicaments, particularly a kind of medicine for the treatment of hepatitis B and preparation method thereof.
Background technology
Hepatitis B (title hepatitis B) is the most extensive at present, a kind of chronic disease that hazardness is the most serious, caused by hepatitis B virus (HBV), show as clinically: weak, loss of appetite, feel sick, vomit, detest oil, hepatomegaly and abnormal liver function etc.Severe patient can cause the disease such as liver cirrhosis, hepatocarcinoma.At present, just copy in hepatocyte with antiviral class medicine prevention hepatitis B virus, thereby play immunoregulation effect, or treat with herbal decoction.
Hepatitis B belongs to a kind of chronic disease.Doctor trained in Western medicine does not have reliable Drug therapy at present, and western medical treatment chronic disease is generally all wanted lifelong medication, bring a lot of inconvenience to patient like this, and can there is side effect in therapeutic process, and also can cause virus variation, other internal organs are also had to certain damage, on the other hand, Chinese medicine decoction treatment does not reach anticipation effect yet, and Traditional Chinese medicine decocting is also pretty troublesome, neither potion two doses can cure.
Summary of the invention
The medicine that the object of the present invention is to provide a kind for the treatment of hepatitis B of pure Chinese herbal and crude drugs preparations, has no side effect, efficacy stability, and treatment and conditioning combine, and play the effect of hepatoprotective.
Another object of the present invention is to provide a kind of preparation method of medicine for the treatment of hepatitis B, and this preparation method is simple, can maximal efficiency extract the effective ingredient in crude drug.
The object of the present invention is achieved like this, and a kind of medicine for the treatment of hepatitis B, in parts by weight, is made up of following crude drug:
Radix Bupleuri, the Radix Paeoniae Alba, Radix Salviae Miltiorrhizae, Semen Arecae, Fructus Aurantii Immaturus, Rhizoma Alismatis, Semen Abutili, Radix Adenophorae (Radix Glehniae), Semen Platycladi, Semen Armeniacae Amarum, Radix Scrophulariae, the Radix Astragali, Herba Artemisiae Scopariae, Fructus Mori, Radix Peucedani, Radix Curcumae, river Huang, Spica Prunellae, Flos Ilicis Asprellae, the Radix Rehmanniae, Radix Sophorae Tonkinensis, Radix Glycyrrhizae.
Preferably contain Radix Bupleuri 1-4 part, Radix Paeoniae Alba 1-4 part, Radix Salviae Miltiorrhizae 2-5 part, Semen Arecae 1-4 part, Fructus Aurantii Immaturus 1-4 part, Rhizoma Alismatis 2-6 part, Semen Abutili 2-6 part, Radix Adenophorae (Radix Glehniae) 2-7 part, Semen Platycladi 1-4 part, Semen Armeniacae Amarum 1-4 part, Radix Scrophulariae 2-5 part, Radix Astragali 0.5-2.5 part, Herba Artemisiae Scopariae 1-4 part, Fructus Mori 1-7 part, Radix Peucedani 1-5 part, Radix Curcumae 1-5 part, the yellow 1-5 part in river, Spica Prunellae 1-4 part, Flos Ilicis Asprellae 1-8 part, Radix Rehmanniae 1-8 part, Radix Sophorae Tonkinensis 1-6 part, Radix Glycyrrhizae 0.5-3 part.Further preferably contain Radix Bupleuri 1.5-3.3 part, Radix Paeoniae Alba 1.5-3.4 part, Radix Salviae Miltiorrhizae 2.5-4.6 part, Semen Arecae 2-3 part, Fructus Aurantii Immaturus 2-3 part, Rhizoma Alismatis 2.6-4 part, Semen Abutili 2.6-5 part, Radix Adenophorae (Radix Glehniae) 3-5 part, Semen Platycladi 2-3 part, Semen Armeniacae Amarum 2-3.2 part, Radix Scrophulariae 2.2-3.8 part, Radix Astragali 0.5-2.4 part, Herba Artemisiae Scopariae 2-3.2 part, Fructus Mori 2.8-4.2 part, Radix Peucedani 2.2-4.3 part, Radix Curcumae 1.8-3.2 part, the yellow 1.6-3 part in river, Spica Prunellae 1.5-2.9 part, Flos Ilicis Asprellae 2-6 part, Radix Rehmanniae 3-5 part, Radix Sophorae Tonkinensis 1.7-4.6 part, Radix Glycyrrhizae 0.8-1.5 part.There is most choosing, contain 2.5 parts of Radix Bupleuri, 2.5 parts of the Radix Paeoniae Albas, 3.5 parts of Radix Salviae Miltiorrhizaes, 2.5 parts of Semen Arecaes, 2.5 parts of Fructus Aurantii Immaturuss, 3 parts of Rhizoma Alismatis, 3 parts of Semen Abutilis, 3.5 parts of Radix Adenophorae (Radix Glehniae), 2.5 parts of Semen Platycladi, 2.5 parts, Semen Armeniacae Amarum, 3 parts of Radix Scrophulariaes, 1.5 parts of the Radixs Astragali, 2.5 parts of Herba Artemisiae Scopariaes, 3.5 parts of Fructus Mori, 2.5 parts of Radix Peucedanis, 2.5 parts of Radix Curcumaes, yellow 2.5 parts of river, 2 parts of Spica Prunellaes, 4 parts of Flos Ilicis Asprellae, 4 parts, the Radix Rehmanniae, 2.5 parts of Radix Sophorae Tonkinensiss, 1 part, Radix Glycyrrhizae.
In above-mentioned each taste crude drug, Radix Bupleuri dispersing the stagnated live-QI to relieve the stagnation of QI, reducing fever by reconciliation; Radix Paeoniae Alba yin fluid astringing suppressing the hyperactive liver, regulating blood flow to alleviate pains; Radix Salviae Miltiorrhizae promoting blood circulation to restore menstrual flow; Herba Artemisiae Scopariae eliminating damp-heat, diuretic jaundice eliminating; The yellow purging heat to relax the bowels in river, removing mass clots absorbing; The promoting the circulation of blood of Radix Curcumae removing heat from blood, promoting the circulation of QI pain relieving; Spica Prunellae clearing away liver-fire, Disperse hepatic depression; Semen Arecae circulation of qi promoting relieving constipation, promoting diuresis to clear away damp pathogen; Fructus Aurantii Immaturus dispelling the stagnated QI removing food stagnancy, reduces phlegm; Semen Armeniacae Amarum reduces phlegm, cough-relieving, sending down the abnormal ascending QI intestine moistening; Rhizoma Alismatis promoting diuresis to eliminate damp pathogen; Semen Abutili diuretic, intestine moistening; Radix Peucedani wind and heat dispersing, the therapeutic method to keep the adverse QI flowing downwards are reduced phlegm; Radix Adenophorae (Radix Glehniae) clearing lung and nourishing yin, heat extraction cough-relieving; Semen Platycladi tranquilizing by nourishing the heart, strengthening the spleen intestine moistening; Radix Astragali invigorating QI to consolidate the body surface resistance, holder skin ulcer granulation promoting; Fructus Mori tonifying kidney for improving eyesight, tonifying YIN nourishes blood; The Radix Sophorae Tonkinensis removing toxic substances of purging heat; Flos Ilicis Asprellae clearing away heat and promoting production of body fluid, scattered silt removing toxic substances; Radix Scrophulariae YIN nourishing and the production of body fluid promoting, Qinghuo Jiedu; Radix Rehmanniae nourishing YIN and clearing away heat, cooling blood for hemostasis; Radix Glycyrrhizae invigorating the spleen and replenishing QI.
Radix Bupleuri Radix Paeoniae Alba Radix Salviae Miltiorrhizae, Herba Artemisiae Scopariae, Radix Curcumae, Radix Et Rhizoma Rhei, Spica Prunellae are monarch drug, Semen Armeniacae Amarum, Fructus Aurantii Immaturus, Semen Arecae, Rhizoma Alismatis, Semen Abutili, Radix Peucedani are ministerial drug, Radix Adenophorae (Radix Glehniae), Semen Platycladi, the Radix Astragali, Fructus Mori are adjuvant drug, Radix Sophorae Tonkinensis, Flos Ilicis Asprellae, the Radix Rehmanniae, Radix Scrophulariae, Radix Glycyrrhizae be for making medicine, and reasonably combined according to monarch, minister, the medication theory helping, make suits the theoretical and pharmacology of Chinese medical formulae theory of pathogen and pathology of tcm, select YAOJING good, prescription is ingenious, and medical knowledge is profound, can be rated as effective good recipe for the treatment of hepatitis B.
The medicine of the treatment hepatitis B of preparing according to this programme, its good drug efficacy, evident in efficacy, to B-type hepatitis treatment targetedly; And the property of medicine is stable, has no adverse reaction.
Treat a preparation method for the medicine of hepatitis B, comprise following preparation process:
1) above-mentioned 22 kinds of crude drug are ground into respectively to mix homogeneously after the smalls of 0.3-0.4 sieve;
2) soak, the 3-4 of the total amount that amount of water is described crude drug doubly;
3) soak after 1-1.5 hour, decoct;
4) extract decoction liquor, and be concentrated into 1-2 times of concentration.
This preparation method is simple, can maximal efficiency extract the effective ingredient in crude drug, the active component content in the medicinal liquid of making is high, kind is many, the impurity of introducing is few, kind is low, drug effect is remarkable.
Whole Chinese herbal medicine powders are broken to 0.3-0.4 sieve, can make like this active ingredient of Chinese herbal medicine fully ooze out, too broken shadow decocts effect.
In decoction process, to produce medicinal residues too much in order reducing, to be difficult for filtering, preferably, in step 3, described soak time is 1.2-1.3 hour.
Described decoction, specifically comprises, described decoction, specifically comprises, first described Radix Salviae Miltiorrhizae, Radix Adenophorae (Radix Glehniae) and Radix Scrophulariae is decocted to 20-25 minute with big fire, then adds remaining crude drug big fire to decoct 10-15 minute, then the 40-60 minute that simmers in water.
When decoction, because the compact structure of ginseng class plant is larger, after needing first its big fire to be decocted to a period of time, then add other crude drug to decoct.First decoct with big fire, impel the medicine elite in it can being separated out rapidly of every taste medical material, simultaneously, for the elite that prevents from separating out is received destruction because of high temperature, and every taste medical material is in the process of separating out, all slow, so need slow fire to decoct for a long time, preferably, the time of slow fire boiling is 1.5-2 hour.
Described decoction comprises 3 times, decocts 1.5-2 hour at every turn, and the medicinal liquid at every turn decocting is mixed.It is 1:(1.5-2 that this medicament is concentrated into concentration), the content of such concentration in 40-50 milliliter medicinal liquid also enough plays therapeutic effect.
In step 4, concentrated concentration is stock solution 1.5 times, drug effect is best.
The medicine of the treatment hepatitis B of preparing by preparation method provided by the invention, also has as follows a little:
Any crowd is suitable for this prescription, efficacy stability.And can play opsonic action in therapeutic process, and the function of the vital organs of the human body is coordinated mutually, play the effect of hepatoprotective simultaneously.
Brief description of the drawings
Fig. 1 is a kind of pharmaceutical production method flow diagram for the treatment of hepatitis B provided by the invention.
Detailed description of the invention
Also by reference to the accompanying drawings the present invention is described in further detail below by specific embodiment.
Treat a medicine for hepatitis B, in parts by weight, made by following crude drug:
Radix Bupleuri, the Radix Paeoniae Alba, Radix Salviae Miltiorrhizae, Semen Arecae, Fructus Aurantii Immaturus, Rhizoma Alismatis, Semen Abutili, Radix Adenophorae (Radix Glehniae), Semen Platycladi, Semen Armeniacae Amarum, Radix Scrophulariae, the Radix Astragali, Herba Artemisiae Scopariae, Fructus Mori, Radix Peucedani, Radix Curcumae, river Huang, Spica Prunellae, Flos Ilicis Asprellae, the Radix Rehmanniae, Radix Sophorae Tonkinensis, Radix Glycyrrhizae.
Treat a preparation method for the medicine of hepatitis B, as shown in Figure 1, comprise following preparation process:
1) above-mentioned 22 kinds of crude drug are ground into respectively to mix homogeneously after the smalls of 0.3-0.4 sieve;
2) soak, the 3-4 of the total amount that amount of water is described crude drug doubly;
3) soak after 1-1.5 hour, decoct;
4) extract decoction liquor, and be concentrated into 1-2 times of concentration.
Embodiment 1:
Prescription: 3 parts of Radix Bupleuri, 2 parts of the Radix Paeoniae Albas, 2 parts of Radix Salviae Miltiorrhizaes, 3 parts of Semen Arecaes, 2 parts of Fructus Aurantii Immaturuss, 4 parts of Rhizoma Alismatis, 3 parts of Semen Abutilis, 5 parts of Radix Adenophorae (Radix Glehniae), 3 parts of Semen Platycladi, 2 parts, Semen Armeniacae Amarum, 2 parts of Radix Scrophulariaes, 1 part of the Radix Astragali, 2 parts of Herba Artemisiae Scopariaes, 1 part of Fructus Mori, 2 parts of Radix Peucedanis, 2 parts of Radix Curcumaes, yellow 1 part of river, 3 parts of Spica Prunellaes, 4 parts of Flos Ilicis Asprellae, 5 parts, the Radix Rehmanniae, 3 parts of Radix Sophorae Tonkinensiss, 2 parts, Radix Glycyrrhizae.
Above 22 taste medical materials are worn into respectively the fine powder of 0.3 sieve, mix homogeneously, is incorporated as the water of 3 times of crude drug total amounts, soaks after 1 hour, first Radix Salviae Miltiorrhizae, Radix Adenophorae (Radix Glehniae) and Radix Scrophulariae are decocted 20 minutes with big fire, add again all the other crude drug big fire to decoct after 10 minutes, transfer slow fire boiling to 40 minutes, decoct altogether 3 times, after the decoction liquor of 3 times is mixed, after being concentrated into concentration and being 1:1.5 through precipitation, after filtering, add antiseptic, then fill finished product.
Example 2:
Prescription: 1.5 parts of Radix Bupleuri, 1.5 parts of the Radix Paeoniae Albas, 3 parts of Radix Salviae Miltiorrhizaes, 2 parts of Semen Arecaes, 2 parts of Fructus Aurantii Immaturuss, 2.6 parts of Rhizoma Alismatis, 3.5 parts of Semen Abutilis, 3 parts of Radix Adenophorae (Radix Glehniae), 2 parts of Semen Platycladi, 2 parts, Semen Armeniacae Amarum, 2.2 parts of Radix Scrophulariaes, 0.5 part of the Radix Astragali, 2 parts of Herba Artemisiae Scopariaes, 2.8 parts of Fructus Mori, 2.2 parts of Radix Peucedanis, 1.8 parts of Radix Curcumaes, yellow 1.6 parts of river, 1.5 parts of Spica Prunellaes, 2 parts of Flos Ilicis Asprellae, 3 parts, the Radix Rehmanniae, 1.7 parts of Radix Sophorae Tonkinensiss, 0.8 part, Radix Glycyrrhizae.
Above 22 taste medical materials are worn into respectively the fine powder of 0.4 sieve, mix homogeneously, is incorporated as the water of 4 times of crude drug total amounts, soaks after 1.5 hours, first Radix Salviae Miltiorrhizae, Radix Adenophorae (Radix Glehniae) and Radix Scrophulariae are decocted 25 minutes with big fire, add again all the other crude drug big fire to decoct after 15 minutes, transfer slow fire boiling to 50 minutes, decoct altogether 3 times, after the decoction liquor of 3 times is mixed, after being concentrated into concentration and being 1:2 through precipitation, after filtering, add antiseptic, then fill finished product.
Example 3:
Prescription: 3.3 parts of Radix Bupleuri, 3.4 parts of the Radix Paeoniae Albas, 4.6 parts of Radix Salviae Miltiorrhizaes, 4 parts of Semen Arecaes, 3 parts of Fructus Aurantii Immaturuss, 4 parts of Rhizoma Alismatis, 5 parts of Semen Abutilis, 3 parts of Radix Adenophorae (Radix Glehniae), 3 parts of Semen Platycladi, 3.2 parts, Semen Armeniacae Amarum, 3.8 parts of Radix Scrophulariaes, 2.4 parts of the Radixs Astragali, 3 parts of Herba Artemisiae Scopariaes, 3 parts of Fructus Mori, 4.3 parts of Radix Peucedanis, 3.2 parts of Radix Curcumaes, yellow 2.5 parts of river, 2 parts of Spica Prunellaes, 4 parts of Flos Ilicis Asprellae, 5 parts, the Radix Rehmanniae, 4.6 parts of Radix Sophorae Tonkinensiss, 1.5 parts, Radix Glycyrrhizae.
Above 22 taste medical materials are worn into respectively the fine powder of 0.3 sieve, mix homogeneously, is incorporated as the water of 3.5 times of crude drug total amounts, soaks after 1 hour, first Radix Salviae Miltiorrhizae, Radix Adenophorae (Radix Glehniae) and Radix Scrophulariae are decocted 20 minutes with big fire, add again all the other crude drug big fire to decoct after 10 minutes, transfer slow fire boiling to 45 minutes, decoct altogether 3 times, after the decoction liquor of 3 times is mixed, after being concentrated into concentration and being 1:1.5 through precipitation, after filtering, add antiseptic, then fill finished product.
Example 4:
2.5 parts of Radix Bupleuri, 2.5 parts of the Radix Paeoniae Albas, 3.5 parts of Radix Salviae Miltiorrhizaes, 2.5 parts of Semen Arecaes, 2.5 parts of Fructus Aurantii Immaturuss, 3 parts of Rhizoma Alismatis, 3 parts of Semen Abutilis, 3.5 parts of Radix Adenophorae (Radix Glehniae), 2.5 parts of Semen Platycladi, 2.5 parts, Semen Armeniacae Amarum, 3 parts of Radix Scrophulariaes, 1.5 parts of the Radixs Astragali, 2.5 parts of Herba Artemisiae Scopariaes, 3.5 parts of Fructus Mori, 2.5 parts of Radix Peucedanis, 2.5 parts of Radix Curcumaes, yellow 2.5 parts of river, 2 parts of Spica Prunellaes, 4 parts of Flos Ilicis Asprellae, 4 parts, the Radix Rehmanniae, 2.5 parts of Radix Sophorae Tonkinensiss, 1 part, Radix Glycyrrhizae.
Above 22 taste medical materials are worn into respectively the fine powder of 0.3 sieve, mix homogeneously, is incorporated as the water of 4 times of crude drug total amounts, soaks after 1 hour, first Radix Salviae Miltiorrhizae, Radix Adenophorae (Radix Glehniae) and Radix Scrophulariae are decocted 20 minutes with big fire, add again all the other crude drug big fire to decoct after 10 minutes, transfer slow fire boiling to 50 minutes, decoct altogether 3 times, after the decoction liquor of 3 times is mixed, after being concentrated into concentration and being 1:1.5 through precipitation, after filtering, add antiseptic, then fill finished product.
Example 5:
Prescription: 1 part of Radix Bupleuri, 1.5 parts of the Radix Paeoniae Albas, 2.5 parts of Radix Salviae Miltiorrhizaes, 3 parts of Semen Arecaes, 2 parts of Fructus Aurantii Immaturuss, 2.6 parts of Rhizoma Alismatis, 4 parts of Semen Abutilis, 5 parts of Radix Adenophorae (Radix Glehniae), 3 parts of Semen Platycladi, 3.2 parts, Semen Armeniacae Amarum, 3.8 parts of Radix Scrophulariaes, 2.4 parts of the Radixs Astragali, 3.2 parts of Herba Artemisiae Scopariaes, 4.2 parts of Fructus Mori, 4.3 parts of Radix Peucedanis, 2 parts of Radix Curcumaes, yellow 2 parts of river, 2.4 parts of Spica Prunellaes, 3 parts of Flos Ilicis Asprellae, 4 parts, the Radix Rehmanniae, 4 parts of Radix Sophorae Tonkinensiss, 2 parts, Radix Glycyrrhizae.
Above 22 taste medical materials are worn into respectively the fine powder of 0.3 sieve, mix homogeneously, is incorporated as the water of 3 times of crude drug total amounts, soaks after 1 hour, first Radix Salviae Miltiorrhizae, Radix Adenophorae (Radix Glehniae) and Radix Scrophulariae are decocted 23 minutes with big fire, add again all the other crude drug big fire to decoct after 14 minutes, transfer slow fire boiling to 45 minutes, decoct altogether 3 times, after the decoction liquor of 3 times is mixed, after being concentrated into concentration and being 1:1.5 through precipitation, after filtering, add antiseptic, then fill finished product.
Example 6:
Prescription: 2 parts of Radix Bupleuri, 4 parts of the Radix Paeoniae Albas, 3 parts of Radix Salviae Miltiorrhizaes, 1 part of Semen Arecae, 1 part of Fructus Aurantii Immaturus, 2 parts of Rhizoma Alismatis, 2 parts of Semen Abutilis, 2 parts of Radix Adenophorae (Radix Glehniae), 1 part of Semen Platycladi, 1 part, Semen Armeniacae Amarum, 3.8 parts of Radix Scrophulariaes, 2.4 parts of the Radixs Astragali, 3.2 parts of Herba Artemisiae Scopariaes, 4.2 parts of Fructus Mori, 4.3 parts of Radix Peucedanis, 2 parts of Radix Curcumaes, yellow 2 parts of river, 1 part of Spica Prunellae, 3 parts of Flos Ilicis Asprellae, 5 parts, the Radix Rehmanniae, 4 parts of Radix Sophorae Tonkinensiss, 2 parts, Radix Glycyrrhizae.
Above 22 taste medical materials are worn into respectively the fine powder of 0.3 sieve, mix homogeneously, is incorporated as the water of 3 times of crude drug total amounts, soaks after 1 hour, first Radix Salviae Miltiorrhizae, Radix Adenophorae (Radix Glehniae) and Radix Scrophulariae are decocted 20 minutes with big fire, add again all the other crude drug big fire to decoct after 15 minutes, transfer slow fire boiling to 40 minutes, decoct altogether 3 times, after the decoction liquor of 3 times is mixed, after being concentrated into concentration and being 1:2 through precipitation, after filtering, add antiseptic, then fill finished product.
Example 7:
Prescription: 3 parts of Radix Bupleuri, 2 parts of the Radix Paeoniae Albas, 4 parts of Radix Salviae Miltiorrhizaes, 4 parts of Semen Arecaes, 3 parts of Fructus Aurantii Immaturuss, 6 parts of Rhizoma Alismatis, 5 parts of Semen Abutilis, 5 parts of Radix Adenophorae (Radix Glehniae), 3 parts of Semen Platycladi, 3 parts, Semen Armeniacae Amarum, 4 parts of Radix Scrophulariaes, 2.5 parts of the Radixs Astragali, 3 parts of Herba Artemisiae Scopariaes, 7 parts of Fructus Mori, 5 parts of Radix Peucedanis, 4 parts of Radix Curcumaes, yellow 4 parts of river, 3 parts of Spica Prunellaes, 6 parts of Flos Ilicis Asprellae, 7 parts, the Radix Rehmanniae, 5 parts of Radix Sophorae Tonkinensiss, 3 parts, Radix Glycyrrhizae.
Above 22 taste medical materials are worn into respectively the fine powder of 0.3 sieve, mix homogeneously, is incorporated as the water of 4 times of crude drug total amounts, soaks after 1 hour, first Radix Salviae Miltiorrhizae, Radix Adenophorae (Radix Glehniae) and Radix Scrophulariae are decocted 25 minutes with big fire, add again all the other crude drug big fire to decoct after 10 minutes, transfer slow fire boiling to 55 minutes, decoct altogether 3 times, after the decoction liquor of 3 times is mixed, after being concentrated into concentration and being 1:2 through precipitation, after filtering, add antiseptic, then fill finished product.
Example 8:
Prescription: 4 parts of Radix Bupleuri, 4 parts of the Radix Paeoniae Albas, 5 parts of Radix Salviae Miltiorrhizaes, 4 parts of Semen Arecaes, 4 parts of Fructus Aurantii Immaturuss, 6 parts of Rhizoma Alismatis, 6 parts of Semen Abutilis, 7 parts of Radix Adenophorae (Radix Glehniae), 4 parts of Semen Platycladi, 4 parts, Semen Armeniacae Amarum, 5 parts of Radix Scrophulariaes, 2.5 parts of the Radixs Astragali, 4 parts of Herba Artemisiae Scopariaes, 7 parts of Fructus Mori, 5 parts of Radix Peucedanis, 5 parts of Radix Curcumaes, yellow 5 parts of river, 4 parts of Spica Prunellaes, 8 parts of Flos Ilicis Asprellae, 86 parts, the Radix Rehmanniae, 6 parts of Radix Sophorae Tonkinensiss, 3 parts, Radix Glycyrrhizae.
Above 22 taste medical materials are worn into respectively the fine powder of 0.3 sieve, mix homogeneously, is incorporated as the water of 4 times of crude drug total amounts, soaks after 1 hour, first Radix Salviae Miltiorrhizae, Radix Adenophorae (Radix Glehniae) and Radix Scrophulariae are decocted 25 minutes with big fire, add again all the other crude drug big fire to decoct after 15 minutes, transfer slow fire boiling to 60 minutes, decoct altogether 3 times, after the decoction liquor of 3 times is mixed, after being concentrated into concentration and being 1:1.5 through precipitation, after filtering, add antiseptic, then fill finished product.
In the time of fill, in order to extend the holding time, can give and wherein add antiseptic, particularly, can add the clean A0.05%-0.1% of benzoic acid 0.25%-0.3% and Ni Bo to mix, directly add in concentrated solution and stir after adding appropriate 10% dissolve with ethanol, benzoic acid efficiency of preservation in acid solution is stronger, poor in alkaline solution, so concentrated solution pH value is transferred under 3.5-5 scope and is added antiseptic.
Finished product medicinal liquid is cool, and to the following fill of 40 degree, after fill, bottleneck is cleaned by alcohol gauze, and then close plug sealing, is stored at room temperature 15-25 DEG C.
With 250mL24 mouth or 26 mouthfuls of vial fills, each serving 40-50 milliliter, clothes, rush decoction being taken warmly with boiled water while clothes sooner or later, and be 24 days a course for the treatment of.
Prescription and preparation method with embodiment 2 and embodiment 8 are prepared respectively medicine for clinical trial, and its clinical test results is as follows:
The present invention used now from making water preparation since 1997, and cure rate is high, without patients with recurrent.
40 patients' of statistics treatment data show:
15 of women, 11 of small three positive, 4 of great three positives, took medicine respectively after 4 courses for the treatment of, and 9 of small three positive are turned out cloudy, and take a turn for the better 2;
Great three positive has 3 to transfer small three positive to, and 1 constant, then all continues to take medicine 4 courses for the treatment of, all turns out cloudy.
25 of male, 18 of small three positive, wherein have 3 hepatic insufficiency, and transaminase is high, and virus (HBV) is normal, and 7 of great three positives, wherein have 5 hepatic insufficiency, have again 2 viruses (HBV) height among these 5.
They took medicine respectively after 4 courses for the treatment of, and liver function is all normal, and virus is all normal, 15 of small three positive recoveries from illness, and great three positive has 4 to transfer small three positive to.
Remainder continues to take medicine 4 courses for the treatment of, only has a liver carrier not turn out cloudy, and all the other are all turned out cloudy.
In view of this, small three positive takes can turn out cloudy 4-6 the course for the treatment of, and great three positive takes can turn out cloudy 6-8 the course for the treatment of, and HBVer may not need to take several courses for the treatment of not etc. more.After patient takes medicine, certainly feel appetite improve, sleep might as well, health strength increase, health is also normal.
Can be found out by above-mentioned clinical test results:
This prescription efficacy stability, effective percentage reaches 100%, and cure rate reaches 95%.And can play opsonic action in therapeutic process, and the function of the vital organs of the human body is coordinated mutually, play the effect of hepatoprotective simultaneously.
The foregoing is only the preferred embodiments of the present invention, be not limited to the present invention, for a person skilled in the art, the present invention can have various modifications and variations.Within the spirit and principles in the present invention all, any amendment of doing, be equal to replacement, improvement etc., within all should being included in protection scope of the present invention.
Claims (10)
1. a medicine for the treatment of hepatitis B, is characterized in that, in parts by weight, is made up of following crude drug:
Radix Bupleuri, the Radix Paeoniae Alba, Radix Salviae Miltiorrhizae, Semen Arecae, Fructus Aurantii Immaturus, Rhizoma Alismatis, Semen Abutili, Radix Adenophorae (Radix Glehniae), Semen Platycladi, Semen Armeniacae Amarum, Radix Scrophulariae, the Radix Astragali, Herba Artemisiae Scopariae, Fructus Mori, Radix Peucedani, Radix Curcumae, river Huang, Spica Prunellae, Flos Ilicis Asprellae, the Radix Rehmanniae, Radix Sophorae Tonkinensis, Radix Glycyrrhizae.
2. a kind of medicine for the treatment of hepatitis B according to claim 1, is characterized in that, in parts by weight, is made up of following crude drug:
Radix Bupleuri 1-4 part, Radix Paeoniae Alba 1-4 part, Radix Salviae Miltiorrhizae 2-5 part, Semen Arecae 1-4 part, Fructus Aurantii Immaturus 1-4 part, Rhizoma Alismatis 2-6 part, Semen Abutili 2-6 part, Radix Adenophorae (Radix Glehniae) 2-7 part, Semen Platycladi 1-4 part, Semen Armeniacae Amarum 1-4 part, Radix Scrophulariae 2-5 part, Radix Astragali 0.5-2.5 part, Herba Artemisiae Scopariae 1-4 part, Fructus Mori 1-7 part, Radix Peucedani 1-5 part, Radix Curcumae 1-5 part, the yellow 1-5 part in river, Spica Prunellae 1-4 part, Flos Ilicis Asprellae 1-8 part, Radix Rehmanniae 1-8 part, Radix Sophorae Tonkinensis 1-6 part, Radix Glycyrrhizae 0.5-3 part.
3. a kind of medicine for the treatment of hepatitis B according to claim 1, is characterized in that, in parts by weight, is made up of following crude drug:
Radix Bupleuri 1.5-3.3 part, Radix Paeoniae Alba 1.5-3.4 part, Radix Salviae Miltiorrhizae 2.5-4.6 part, Semen Arecae 2-3 part, Fructus Aurantii Immaturus 2-3 part, Rhizoma Alismatis 2.6-4 part, Semen Abutili 2.6-5 part, Radix Adenophorae (Radix Glehniae) 3-5 part, Semen Platycladi 2-3 part, Semen Armeniacae Amarum 2-3.2 part, Radix Scrophulariae 2.2-3.8 part, Radix Astragali 0.5-2.4 part, Herba Artemisiae Scopariae 2-3.2 part, Fructus Mori 2.8-4.2 part, Radix Peucedani 2.2-4.3 part, Radix Curcumae 1.8-3.2 part, the yellow 1.6-3 part in river, Spica Prunellae 1.5-2.9 part, Flos Ilicis Asprellae 2-6 part, Radix Rehmanniae 3-5 part, Radix Sophorae Tonkinensis 1.7-4.6 part, Radix Glycyrrhizae 0.8-1.5 part.
4. a kind of medicine for the treatment of hepatitis B according to claim 1, is characterized in that, in parts by weight, is made up of following crude drug:
2.5 parts of Radix Bupleuri, 2.5 parts of the Radix Paeoniae Albas, 3.5 parts of Radix Salviae Miltiorrhizaes, 2.5 parts of Semen Arecaes, 2.5 parts of Fructus Aurantii Immaturuss, 3 parts of Rhizoma Alismatis, 3 parts of Semen Abutilis, 3.5 parts of Radix Adenophorae (Radix Glehniae), 2.5 parts of Semen Platycladi, 2.5 parts, Semen Armeniacae Amarum, 3 parts of Radix Scrophulariaes, 1.5 parts of the Radixs Astragali, 2.5 parts of Herba Artemisiae Scopariaes, 3.5 parts of Fructus Mori, 2.5 parts of Radix Peucedanis, 2.5 parts of Radix Curcumaes, yellow 2.5 parts of river, 2 parts of Spica Prunellaes, 4 parts of Flos Ilicis Asprellae, 4 parts, the Radix Rehmanniae, 2.5 parts of Radix Sophorae Tonkinensiss, 1 part, Radix Glycyrrhizae.
5. according to the preparation method of a kind of medicine for the treatment of hepatitis B described in claim 1-4 any one, it is characterized in that, comprise following preparation process:
1) above-mentioned 22 kinds of crude drug are ground into respectively to mix homogeneously after the smalls of 0.3-0.4 sieve;
2) soak, the 3-4 of the total amount that amount of water is described crude drug doubly;
3) soak after 1-1.5 hour, decoct;
4) extract decoction liquor, and be concentrated into 1-2 times of concentration.
6. the preparation method of a kind of medicine for the treatment of hepatitis B according to claim 5, is characterized in that:
In step 3, described soak time is 1.2-1.3 hour.
7. the preparation method of a kind of medicine for the treatment of hepatitis B according to claim 5, is characterized in that:
In step 3, described decoction, specifically comprises, first described Radix Salviae Miltiorrhizae, Radix Adenophorae (Radix Glehniae) and Radix Scrophulariae is decocted to 20-25 minute with big fire, then adds remaining crude drug big fire to decoct 10-15 minute, then the 40-60 minute that simmers in water.
8. the preparation method of a kind of medicine for the treatment of hepatitis B according to claim 5, is characterized in that:
In step 3, described decoction comprises 3 times, decocts 1.5-2 hour at every turn, and the medicinal liquid at every turn decocting is mixed.
9. the preparation method of a kind of medicine for the treatment of hepatitis B according to claim 5, is characterized in that:
In step 2, described water is distilled water.
10. the preparation method of a kind of medicine for the treatment of hepatitis B according to claim 5, is characterized in that:
In step 4, concentrated concentration is stock solution 1.5 times.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410200135.2A CN103948875A (en) | 2014-05-13 | 2014-05-13 | Medicine for treating hepatitis B and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410200135.2A CN103948875A (en) | 2014-05-13 | 2014-05-13 | Medicine for treating hepatitis B and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN103948875A true CN103948875A (en) | 2014-07-30 |
Family
ID=51326316
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410200135.2A Pending CN103948875A (en) | 2014-05-13 | 2014-05-13 | Medicine for treating hepatitis B and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103948875A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105770721A (en) * | 2014-12-22 | 2016-07-20 | 天津嘉创生物科技有限公司 | Traditional Chinese medicine preparation for preventing and treating puerperal fever of sow and preparation method thereof |
| CN106075107A (en) * | 2016-05-31 | 2016-11-09 | 安徽皖斛堂生物科技有限公司 | A kind of Herba Dendrobii tablet of liver protecting and nourishing |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1136939A (en) * | 1995-10-10 | 1996-12-04 | 卢颖 | Chinese drugs for curing hepatitis B |
| CN102949658A (en) * | 2011-08-18 | 2013-03-06 | 张志通 | Drug formula for treating hepatitis |
-
2014
- 2014-05-13 CN CN201410200135.2A patent/CN103948875A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1136939A (en) * | 1995-10-10 | 1996-12-04 | 卢颖 | Chinese drugs for curing hepatitis B |
| CN102949658A (en) * | 2011-08-18 | 2013-03-06 | 张志通 | Drug formula for treating hepatitis |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105770721A (en) * | 2014-12-22 | 2016-07-20 | 天津嘉创生物科技有限公司 | Traditional Chinese medicine preparation for preventing and treating puerperal fever of sow and preparation method thereof |
| CN106075107A (en) * | 2016-05-31 | 2016-11-09 | 安徽皖斛堂生物科技有限公司 | A kind of Herba Dendrobii tablet of liver protecting and nourishing |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103463528A (en) | Traditional Chinese medicine composition for treating chronic eczema | |
| CN102000301A (en) | Traditional Chinese medicine composite for treating mammitis and lobular hyperplasia of mammary gland and preparation method thereof | |
| CN102526691A (en) | External application plaster for treating dysmenorrhea | |
| CN103705866A (en) | Traditional Chinese medicine composition for treating hypomenorrhea | |
| CN103301440B (en) | Chinese medicine capable of warming Yang and tonifying kidneys | |
| CN101020031A (en) | Acne treating Chinese herbal medicine prepn | |
| CN103720996A (en) | Traditional Chinese medicinal composition for treating dysmenorrhea | |
| CN101391015A (en) | External traditional Chinese medicine powder for treating recurrent hemorrhoid | |
| CN101703742B (en) | Preparation method of granules for treating acne caused by qi deficiency causing blood stasis and phlegm-heat stagnation | |
| CN103316192A (en) | Traditional Chinese medicine foot-bathing liquid for treating lumbocrural pain and preparation method thereof | |
| CN104524159A (en) | Pharmaceutical composition for treating hyperplasia of mammary glands | |
| CN103948875A (en) | Medicine for treating hepatitis B and preparation method thereof | |
| CN105250427A (en) | Pharmaceutical composition for treating heart diseases | |
| CN103341013A (en) | Traditional Chinese medicine for treating pain in waist and legs | |
| CN105287949A (en) | Traditional Chinese medicinal composition for treating dysmenorrhea | |
| CN101530592B (en) | Traditional Chinese medicine for treating diabetic gastroparesis | |
| CN1320914C (en) | Menstruation regulating powder | |
| CN104225282A (en) | Traditional Chinese medicine for treating postpartum headache | |
| CN1207025C (en) | Haidan medicine for treating cardiac and cerebral vascular diseases and its prepn | |
| CN104825892B (en) | A kind of Chinese medicine preparation for treating ovulation bleeding and preparation method thereof | |
| CN105267414A (en) | Alopecia-stopping hair-growing traditional Chinese medicine combination and preparation method of oral solution preparation thereof | |
| CN104288689A (en) | Traditional Chinese medicine for treating mucocutaneous lymph node syndromes and preparation method of traditional Chinese medicine | |
| CN105362999A (en) | Traditional Chinese medicine preparation for preventing and treating infantile repeated cold and preparation method thereof | |
| CN105521384A (en) | Gynecological medicine for treating pregnancy complications, and preparation method thereof | |
| CN118634281A (en) | Composition for treating anxiety-type insomnia, preparation method, medicine and application thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20140730 |
|
| RJ01 | Rejection of invention patent application after publication |