CN103948840A - Traditional Chinese medicine additive for treating swine allotriophagia and preparation method thereof - Google Patents
Traditional Chinese medicine additive for treating swine allotriophagia and preparation method thereof Download PDFInfo
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P60/00—Technologies relating to agriculture, livestock or agroalimentary industries
- Y02P60/80—Food processing, e.g. use of renewable energies or variable speed drives in handling, conveying or stacking
- Y02P60/87—Re-use of by-products of food processing for fodder production
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a traditional Chinese medicine additive for treating swine allotriophagia and a preparation method thereof. The traditional Chinese medicine additive is prepared from the following raw medicines: neopallasia pectinata, mallow, ajuga nipponensis, rhizoma atractylodis, rhizoma pleionis leaf, concha ostreae, philippine violet herb, fossil fragments, betel nut, herba epimedii, cortex acanthopanacis, poria cocos, radix paeoniae alba, rheum officinale, pericarpium citri reticulatae, gymnema sylvestre schult, garlic, goose saliva, angelica sinensis, codonopsis pilosula, rhizoma atractylodis macrocephalae, fructus aurantii, mangnolia officinalis, fructus forsythia, cape jasmine, sesarma dehaani, medicated leaven, colysis bonii, malt, phlomis tuberosa, cirsium esculentum, gardneria multiflora, vitis flexuosa, cayratia japonica and drymotaenium miyoshianum. The traditional Chinese medicine additive has the advantages of being high in effect on treating swine allotriophagia and small in toxic ad side effects, improving the immunity of swine, and promoting healthy growth of swine; in addition, the traditional Chinese medicine additive also has the effects of tonifying spleen and regulating stomach, promoting Qi circulation and strengthening middle warmer, and expelling parasite and helping digestion.
Description
Technical field
The present invention relates to Chinese medicine preparation technical field, relate in particular to a kind of Chinese medicine additive that is used for the treatment of pig pica and preparation method thereof.
Background technology
Pig pica, be a kind of because feeding and management is improper, environment is uncomfortable, a kind of irritability syndrome of causing such as feed nutrition supply imbalance, disease and metabolism disorder.Autumn and winter sickness rate higher, cause unnecessary economic loss to pig farmer.
Common pig pica shows as: tail biting, sting ear, sting rib, suck umbilicus, the phenomenon such as coprophagy, drink urinate, dig earth with the snout, noisy circle, hurdle race, sow infanticide pig.Mutually stinging bucket is one comparatively severe in pica, shows as pig to outside stimulus sensitivity, manner uneasiness, and appetite weakens, sight fierceness.Originally only having several mutually to sting bucket, have gradually bull to participate in, is mainly tail biting, and minority is also stung ear, common hemorrhage by tail biting depilation, stings pig and then has a liking for blood generation is different, causes Tail-Biting, and harm also expands gradually.Be snapped pig and often occur tail skin and come off by hair, affect body weight gains, can secondary infection when serious, cause osteomyelitis and abscess, if processing not in time can concurrent septicemia etc. causes death.
The common morbidity of pig pica because:
1, feeding and management is improper: comprise that stocking density is excessive, feed trough narrow space, limit raise that the strong and the weak differ greatly, pig new and group causes and fights, fights for the reasons such as precedence and all can bring out pica with subimbition, same colony house pig size.
2, environmental factors: the higher reason of pig sickness rate in autumn in winter may be dry and dirty environment has caused the more agitation of pig and aggressive behavior.Pig house environment condition is poor, as give up interior too high or too low for temperature, the accumulating of improper ventilation and harmful gas, pig house illumination is excessively strong, pig is in excitatory state and dysphoria, pig living environment dullness, disorderly string group of scaring, pig; The ANOMALOUS VARIATIONS of weather, factor that pigsty humidity causes that skin is itched etc., makes pig produce sense of discomfort or has a rest the bad equal generation that can cause picas such as biting.
3, kind and individual variation: if raise different cultivars or the different excessive pig of the same kind mesosome method of double differences in same pigsty, because of kind and life characteristic difference, conflicting, mutually contend for supremacy and male servant occurs sting.Interindividual variation is large, occupying sleep area and robbing in food, often occurs the strong bullies the weak phenomenon.
4, disease: when pig suffers from the vermin such as louse, scabies, can cause pig body skin irritation and dysphoria, cause after ear at house internal friction, flank etc. locates to occur exudate, and other pigs are produced sucking action and bring out tail biting; Pig endobiosis parasitosis, particularly ascaris suum, stimulate affected pig to attack other pigs.In pig body, hormonal stimulation causes emotional instability that tail biting phenomenon also can occur.
5, nutrition supply imbalance: when feed nutrition level is lower than feeding standard, can cause the generation of tail biting disease while can not meet the nutritional need of pig growth and development.In addition, the various micro-nutrient composition imbalances in daily ration, as shortage or the imbalance of potassium, sodium, magnesium, ferrum, calcium, phosphorus, vitamin etc. in daily ration also can cause this disease.
6, the nature of pig itself: pig is liked to play active, in amenity, the piglets of living and working in peace and contentment, sting the tail of other pigs and play, and the imitativeness of pig is a pig generation pica and cause one of reason of jumpbogroup generation pica.Simultaneously, because stinging mutually the broken skin that causes and the wound such as bleeding, bring out again the interest that pig stings mutually with each other.
The existing Therapeutic Principle of doctor trained in Western medicine and method are mainly: strengthen feeding and management, build good living environment; Piglet is docked in time: to pigling, docking is a kind of effective measures of controlling tail biting disease; Disperse pig attention: in pigsty, throw in toy as chain, ball, old tire and green forage etc., the focus of disperseing pig to pay close attention to, thus reduce the generation of tail biting disease; The mixed feed of balance nutrition, meets the nutritional need of pig.Select high-quality feed raw material, in material, can add full nutrition element " to swash raw peptide "; Medication to the ill, controls pica.To suffering from the pig of chronic gastrointestinal disease, treatment mainly taking inhibiting bacteria and diminishing inflammation, remove intestinal toxic material as principle, and in conjunction with fluid infusion, heart tonifying measure.For the pig that suffers from parasitic disease, should be in time with anthelmintics such as clean happy prestige.For the outside sterilization of the pig of being bitten, and be aided with antibiotic therapy.
But not only cost is higher for western medical treatment pig pica, and the course for the treatment of is longer, therapeutic effect is undesirable, easily recurrence, and drug residue is also larger.Bread is the staff of life, and Carnis Sus domestica is directly connected to the healthy of broad masses of the people as its quality safety of important animal-derived food.Therefore, accumulate over a long period, the Western medicine residual quantity increasing gradually has a strong impact on the healthy safety of consumer.
Chinese veterinarian thinks, pig pica is one of clinical common disease, for Nutrition and Metabolism is not normal, the syndrome of parageusia and the feeding and management a kind of complexity causing such as improper.Clinically taking the foreign body of licking everywhere, bite as feature.Pica can cause pig anorexia, hypoevolutism, affects the fertility performance of pig.Pig pica is because of pig generation forestomach atony mostly, dyspepsia, and pig is poor to the digestive and absorptive functions of food, cause pig malnutrition, add that pig appetite is depressed, parageusia, make like this pig just occur pica, as can be seen here, its root of pig pica is due to pig dyspepsia.
Summary of the invention
Technical problem to be solved by this invention is to be: a kind of Chinese medicine additive that is used for the treatment of pig pica is provided, Chinese medicine additive of the present invention is aspect treatment pig pica, there is curative effect high, toxic and side effects is low, can improve pig immunity, promote the advantage of pig very fast healthy growth, also there is in addition the effect that spleen invigorating reason stomach, circulation of qi promoting invigorating middle warmer, parasite killing help digestion.
In order to realize foregoing invention object, the invention provides a kind of Chinese medicine additive that is used for the treatment of pig pica, described Chinese medicine additive comprises following raw medicinal material: comb leaf Artemisia, Radix Malvae sylvestris, Herba boeae clarkeanae, Rhizoma Atractylodis, Folium Cremastrae appendiculatae, Concha Ostreae, Herba Violae philippicae, Os Draconis, Semen Arecae, Herba Epimedii, Cortex Acanthopancis, Poria, the Radix Paeoniae Alba, Radix Et Rhizoma Rhei, Pericarpium Citri Reticulatae, Largeleaf Gymnema, Bulbus Allii, Sputum Anseris domestica, Radix Angelicae Sinensis, Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, Fructus Aurantii, Cortex Magnoliae Officinalis, Fructus Forsythiae, Fructus Gardeniae, crab Qi, Massa Medicata Fermentata, Colysis bonii Ching., Fructus Hordei Germinatus, Herba Phlomidis Tuberosae, Herba cirsii esculenti, Peng Lai Pueraria lobota, Pueraria lobota Bud, Herba Cayatiae Japonicae and Drymotaenium miyoshianum (Mak.) Mak..
Wherein, in Chinese medicine additive, the parts by weight of each raw medicinal material are preferably: comb leaf Artemisia 15-35 weight portion, Radix Malvae sylvestris 10-30 weight portion, Herba boeae clarkeanae 10-25 weight portion, Rhizoma Atractylodis 15-35 weight portion, Folium Cremastrae appendiculatae 10-35 weight portion, Concha Ostreae 10-30 weight portion, Herba Violae philippicae 15-35 weight portion, Os Draconis 10-30 weight portion, Semen Arecae 15-35 weight portion, Herba Epimedii 15-35 weight portion, Cortex Acanthopancis 10-30 weight portion, Poria 15-35 weight portion, Radix Paeoniae Alba 10-30 weight portion, Radix Et Rhizoma Rhei 15-35 weight portion, Pericarpium Citri Reticulatae 10-30 weight portion, Largeleaf Gymnema 10-30 weight portion, Bulbus Allii 15-35 weight portion, Sputum Anseris domestica 10-30 weight portion, Radix Angelicae Sinensis 15-35 weight portion, Radix Codonopsis 10-30 weight portion, Rhizoma Atractylodis Macrocephalae 15-35 weight portion, Fructus Aurantii 10-30 weight portion, Cortex Magnoliae Officinalis 10-30 weight portion, Fructus Forsythiae 15-30 weight portion, Fructus Gardeniae 10-30 weight portion, crab Qi 15-35 weight portion, Massa Medicata Fermentata 10-30 weight portion, Colysis bonii Ching. 15-35 weight portion, Fructus Hordei Germinatus 10-30 weight portion, Herba Phlomidis Tuberosae 15-35 weight portion, Herba cirsii esculenti 10-30 weight portion, Peng Lai Pueraria lobota 15-35 weight portion, Pueraria lobota Bud 10-30 weight portion, Herba Cayatiae Japonicae 15-35 weight portion and Drymotaenium miyoshianum (Mak.) Mak. 10-30 weight portion.
Wherein, in Chinese medicine additive, the parts by weight of each raw medicinal material can also be preferably: comb leaf Artemisia 15-25 weight portion, Radix Malvae sylvestris 15-30 weight portion, Herba boeae clarkeanae 15-25 weight portion, Rhizoma Atractylodis 15-30 weight portion, Folium Cremastrae appendiculatae 15-35 weight portion, Concha Ostreae 15-30 weight portion, Herba Violae philippicae 15-30 weight portion, Os Draconis 15-30 weight portion, Semen Arecae 15-30 weight portion, Herba Epimedii 15-30 weight portion, Cortex Acanthopancis 15-30 weight portion, Poria 15-30 weight portion, Radix Paeoniae Alba 15-30 weight portion, Radix Et Rhizoma Rhei 15-30 weight portion, Pericarpium Citri Reticulatae 15-30 weight portion, Largeleaf Gymnema 15-30 weight portion, Bulbus Allii 15-30 weight portion, Sputum Anseris domestica 15-30 weight portion, Radix Angelicae Sinensis 15-30 weight portion, Radix Codonopsis 15-30 weight portion, Rhizoma Atractylodis Macrocephalae 15-30 weight portion, Fructus Aurantii 15-30 weight portion, Cortex Magnoliae Officinalis 15-25 weight portion, Fructus Forsythiae 15-25 weight portion, Fructus Gardeniae 15-30 weight portion, crab Qi 15-30 weight portion, Massa Medicata Fermentata 15-30 weight portion, Colysis bonii Ching. 15-30 weight portion, Fructus Hordei Germinatus 15-30 weight portion, Herba Phlomidis Tuberosae 15-30 weight portion, Herba cirsii esculenti 10-25 weight portion, Peng Lai Pueraria lobota 15-30 weight portion, Pueraria lobota Bud 15-30 weight portion, Herba Cayatiae Japonicae 15-30 weight portion and Drymotaenium miyoshianum (Mak.) Mak. 15-30 weight portion.
Wherein, in Chinese medicine additive, the parts by weight of each raw medicinal material can be preferably again: comb leaf Artemisia 18 weight portions, Radix Malvae sylvestris 17 weight portions, Herba boeae clarkeanae 25 weight portions, Rhizoma Atractylodis 25 weight portions, Folium Cremastrae appendiculatae 30 weight portions, Concha Ostreae 18 weight portions, Herba Violae philippicae 22 weight portions, Os Draconis 25 weight portions, Semen Arecae 20 weight portions, Herba Epimedii 28 weight portions, Cortex Acanthopancis 18 weight portions, Poria 17 weight portions, the Radix Paeoniae Alba 22 weight portions, Radix Et Rhizoma Rhei 25 weight portions, Pericarpium Citri Reticulatae 22 weight portions, Largeleaf Gymnema 17 weight portions, Bulbus Allii 20 weight portions, Sputum Anseris domestica 25 weight portions, Radix Angelicae Sinensis 18 weight portions, Radix Codonopsis 25 weight portions, the Rhizoma Atractylodis Macrocephalae 19 weight portions, Fructus Aurantii 25 weight portions, Cortex Magnoliae Officinalis 17 weight portions, Fructus Forsythiae 22 weight portions, Fructus Gardeniae 28 weight portions, crab Qi 18 weight portions, Massa Medicata Fermentata 22 weight portions, Colysis bonii Ching. 25 weight portions, Fructus Hordei Germinatus 18 weight portions, Herba Phlomidis Tuberosae 17 weight portions, Herba cirsii esculenti 20 weight portions, Peng Lai Pueraria lobota 22 weight portions, Pueraria lobota Bud 25 weight portions, Herba Cayatiae Japonicae 28 weight portions and Drymotaenium miyoshianum (Mak.) Mak. 19 weight portions.
Wherein, described Chinese medicine additive Raw medical material also comprises: Herba Zanthoxyli Myriacanthi, Carnis cauda Anseris domestica, Rui Liancao, Herba Scorzonerae Divaricatae and Rhizoma Smilacis.
Wherein, in Chinese medicine additive, the parts by weight of each raw medicinal material can be preferably: comb leaf Artemisia 15-35 weight portion, Radix Malvae sylvestris 10-30 weight portion, Herba boeae clarkeanae 10-25 weight portion, Rhizoma Atractylodis 15-35 weight portion, Folium Cremastrae appendiculatae 10-35 weight portion, Concha Ostreae 10-30 weight portion, Herba Violae philippicae 15-35 weight portion, Os Draconis 10-30 weight portion, Semen Arecae 15-35 weight portion, Herba Epimedii 15-35 weight portion, Cortex Acanthopancis 10-30 weight portion, Poria 15-35 weight portion, Radix Paeoniae Alba 10-30 weight portion, Radix Et Rhizoma Rhei 15-35 weight portion, Pericarpium Citri Reticulatae 10-30 weight portion, Largeleaf Gymnema 10-30 weight portion, Bulbus Allii 15-35 weight portion, Sputum Anseris domestica 10-30 weight portion, Radix Angelicae Sinensis 15-35 weight portion, Radix Codonopsis 10-30 weight portion, Rhizoma Atractylodis Macrocephalae 15-35 weight portion, Fructus Aurantii 10-30 weight portion, Cortex Magnoliae Officinalis 10-30 weight portion, Fructus Forsythiae 15-30 weight portion, Fructus Gardeniae 10-30 weight portion, crab Qi 15-35 weight portion, Massa Medicata Fermentata 10-30 weight portion, Colysis bonii Ching. 15-35 weight portion, Fructus Hordei Germinatus 10-30 weight portion, Herba Phlomidis Tuberosae 15-35 weight portion, Herba cirsii esculenti 10-30 weight portion, Peng Lai Pueraria lobota 15-35 weight portion, Pueraria lobota Bud 10-30 weight portion, Herba Cayatiae Japonicae 15-35 weight portion, Drymotaenium miyoshianum (Mak.) Mak. 10-30 weight portion, Herba Zanthoxyli Myriacanthi 15-35 weight portion, Carnis cauda Anseris domestica 10-25 weight portion, the careless 10-20 weight portion of auspicious company, Herba Scorzonerae Divaricatae 15-35 weight portion and Rhizoma Smilacis 10-30 weight portion.
Wherein, in Chinese medicine additive, the parts by weight of each raw medicinal material can also be preferably: comb leaf Artemisia 25 weight portions, Radix Malvae sylvestris 22 weight portions, Herba boeae clarkeanae 18 weight portions, Rhizoma Atractylodis 25 weight portions, Folium Cremastrae appendiculatae 17 weight portions, Concha Ostreae 28 weight portions, Herba Violae philippicae 17 weight portions, Os Draconis 22 weight portions, Semen Arecae 20 weight portions, Herba Epimedii 25 weight portions, Cortex Acanthopancis 28 weight portions, Poria 22 weight portions, the Radix Paeoniae Alba 19 weight portions, Radix Et Rhizoma Rhei 18 weight portions, Pericarpium Citri Reticulatae 20 weight portions, Largeleaf Gymnema 27 weight portions, Bulbus Allii 19 weight portions, Sputum Anseris domestica 28 weight portions, Radix Angelicae Sinensis 18 weight portions, Radix Codonopsis 25 weight portions, the Rhizoma Atractylodis Macrocephalae 28 weight portions, Fructus Aurantii 25 weight portions, Cortex Magnoliae Officinalis 18 weight portions, Fructus Forsythiae 20 weight portions, Fructus Gardeniae 22 weight portions, crab Qi 25 weight portions, Massa Medicata Fermentata 28 weight portions, Colysis bonii Ching. 18 weight portions, Fructus Hordei Germinatus 28 weight portions, Herba Phlomidis Tuberosae 17 weight portions, Herba cirsii esculenti 25 weight portions, Peng Lai Pueraria lobota 27 weight portions, Pueraria lobota Bud 25 weight portions, Herba Cayatiae Japonicae 18 weight portions, Drymotaenium miyoshianum (Mak.) Mak. 27 weight portions, Herba Zanthoxyli Myriacanthi 20 weight portions, Carnis cauda Anseris domestica 22 weight portions, careless 20 weight portions of auspicious company, Herba Scorzonerae Divaricatae 30 weight portions and Rhizoma Smilacis 28 weight portions.
Wherein, in Chinese medicine additive, the parts by weight of each raw medicinal material can be preferably again: comb leaf Artemisia 15 weight portions, Radix Malvae sylvestris 30 weight portions, Herba boeae clarkeanae 25 weight portions, Rhizoma Atractylodis 30 weight portions, Folium Cremastrae appendiculatae 35 weight portions, Concha Ostreae 30 weight portions, Herba Violae philippicae 28 weight portions, Os Draconis 25 weight portions, Semen Arecae 28 weight portions, Herba Epimedii 30 weight portions, Cortex Acanthopancis 20 weight portions, Poria 30 weight portions, the Radix Paeoniae Alba 28 weight portions, Radix Et Rhizoma Rhei 28 weight portions, Pericarpium Citri Reticulatae 22 weight portions, Largeleaf Gymnema 18 weight portions, Bulbus Allii 22 weight portions, Sputum Anseris domestica 25 weight portions, Radix Angelicae Sinensis 18 weight portions, Radix Codonopsis 25 weight portions, the Rhizoma Atractylodis Macrocephalae 28 weight portions, Fructus Aurantii 27 weight portions, Cortex Magnoliae Officinalis 25 weight portions, Fructus Forsythiae 22 weight portions, Fructus Gardeniae 30 weight portions, crab Qi 22 weight portions, Massa Medicata Fermentata 19 weight portions, Colysis bonii Ching. 25 weight portions, Fructus Hordei Germinatus 18 weight portions, Herba Phlomidis Tuberosae 28 weight portions, Herba cirsii esculenti 25 weight portions, Peng Lai Pueraria lobota 19 weight portions, Pueraria lobota Bud 27 weight portions, Herba Cayatiae Japonicae 17 weight portions, Drymotaenium miyoshianum (Mak.) Mak. 22 weight portions, Herba Zanthoxyli Myriacanthi 25 weight portions, Carnis cauda Anseris domestica 20 weight portions, careless 17 weight portions of auspicious company, Herba Scorzonerae Divaricatae 28 weight portions and Rhizoma Smilacis 22 weight portions.
In order better to realize foregoing invention object, the present invention also provides the preparation method of the Chinese medicine additive for the treatment of pig pica, and described preparation method comprises the following steps:
Step 1, take all raw medicinal materials according to parts by weight, and be ground into 40 order-60 object powder;
Step 2, above-mentioned gained powder is carried out to charcoal fry 1.0-2.5 hour, adding subsequently with respect to mixture quality 2-4 determining alcohol is doubly 75%-85% alcoholic solution, and heating and refluxing extraction 4.5-7 hour obtains the first extracting solution, filters, and obtains the first filtrate; It is 65%-90% alcoholic solution that filtering residue adds with respect to its quality 2-5 determining alcohol doubly again, heating and refluxing extraction 1.5-3 hour, obtains the second extracting solution, filters, obtain the second filtrate, the first filtrate and the second filtrate are merged, be uniformly mixed, concentrating under reduced pressure, remove ethanol, obtain dry mastic, adopt subsequently pulverizer that dry gained mastic is pulverized, grinding particle size 270 order-400 orders, obtain pulverous described Chinese medicine additive.
The beneficial effect that the technical scheme that the embodiment of the present invention provides is brought is: Chinese medicine additive of the present invention is aspect treatment pig pica, there is curative effect high, toxic and side effects is low, can improve pig immunity, promote the advantage of pig very fast healthy growth, also there is in addition the effect that spleen invigorating reason stomach, circulation of qi promoting invigorating middle warmer, parasite killing help digestion.
Detailed description of the invention
The invention provides a kind of Chinese medicine additive that is used for the treatment of pig pica, Chinese medicine additive comprises following raw medicinal material: comb leaf Artemisia, Radix Malvae sylvestris, Herba boeae clarkeanae, Rhizoma Atractylodis, Folium Cremastrae appendiculatae, Concha Ostreae, Herba Violae philippicae, Os Draconis, Semen Arecae, Herba Epimedii, Cortex Acanthopancis, Poria, the Radix Paeoniae Alba, Radix Et Rhizoma Rhei, Pericarpium Citri Reticulatae, Largeleaf Gymnema, Bulbus Allii, Sputum Anseris domestica, Radix Angelicae Sinensis, Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, Fructus Aurantii, Cortex Magnoliae Officinalis, Fructus Forsythiae, Fructus Gardeniae, crab Qi, Massa Medicata Fermentata, Colysis bonii Ching., Fructus Hordei Germinatus, Herba Phlomidis Tuberosae, Herba cirsii esculenti, Peng Lai Pueraria lobota, Pueraria lobota Bud, Herba Cayatiae Japonicae, Drymotaenium miyoshianum (Mak.) Mak., preferably can also comprise Herba Zanthoxyli Myriacanthi, Carnis cauda Anseris domestica, the auspicious grass that connects, Herba Scorzonerae Divaricatae and Rhizoma Smilacis.
The pharmacological properties of each raw medicinal material is as follows:
Rhizoma Atractylodis: nature and flavor are pungent, bitter, temperature.Return spleen, stomach, Liver Channel.Cure mainly: the transporting imbalance that the spleen being blocked by dampness causes, inappetence, vomiting is unhappy, and abdominal distention is had loose bowels, arthralgia.For dampness taste, distension and fullness in the abdomen, cold-damp leucorrhea, damp-warm diseases and damp invasion of lower energizer, foot swelling and pain in knee, flaccidity are soft unable.Control dampness taste, and see the thick disease such as turbid of distension and fullness in the abdomen, inappetence, fatigue and weakness, white and greasy fur.Rhizoma Atractylodis have drying damp and strengthening spleen, effect of wind-damp dispelling.Cure mainly retention of dampness in middle-JIAO, anemofrigid-damp arthralgia, foot swelling and pain in knee, flaccidity is soft unable, nyctalopia nyctalopia." pearl sac " day: " can stomach invigorating pacify spleen, non-this of all damp-edema can not remove." Compendium of Material Medica says: " control damp-phlegm prolonged fluid-retention ... and spleen is wet dirty, turbid drop leukorrhagia, the sliding hemorrhoidal hamorrhage that rushes down." " Newly Revised Canon of Materia Medica " claim that it can " diuresis ".
Concha Ostreae: nature and flavor are salty, is slightly cold; Return liver, gallbladder, kidney channel.Belong to yin-nourishing drug.Modern study shows that in Concha Ostreae, contained abundant taurine has obvious hepatic cholagogic effect, and this is also the good medicine of control pregnancy period functional condition in intrahepatic cholestasis; Contained trace element and the glycogen of enriching, to promote fetus growth promoter, rescue pregnant woman anemia and all beneficial to anemia of pregnant woman's antisecosis; Concha Ostreae is again the best food of replenishing the calcium, and it is phosphorous very abundant, needs the help of phosphorus when absorbing in calcium body, so be conducive to the absorption of calcium; Concha Ostreae also contains vitamin B12, and this is that general food lacks, and the brill element in vitamin B12 is the indispensable material of prevention pernicious anemia, thereby Concha Ostreae has again the effect of the hemopoietic function enlivened; In Concha Ostreae, in contained protein, have multiple good aminoacid, these aminoacid have Detoxication, can remove the noxious substance in body.Also have the effect of tonifying YIN YANG hyperactivity suppressing, can be used for the agitation that hyperactivity of YANG due to deficiency of YIN causes, insomnia, dizziness headache, one's ears rang and spots danced before one's eyes, hectic fever night sweat; Stomachache pantothenic acid etc.Compendium of Material Medica is recorded: Carnis ostreae " polyphagia it, can fine work skin, kidney invigorating and YANG supporting, and can control void, separates erysipelas ".The traditional Chinese medical science thinks that the meat of Concha Ostreae has good food therapy value, be simply extraordinary YIN nourishing, enrich blood, and can also excite the food of libido, be specially adapted to the people of asthenia, deficient sufferer and those deficiency of YIN, anemia, insufficiency of vital energy and blood.
Os Draconis: sweet puckery, flat.Enter the heart, liver, kidney, large intestine channel.Can tranquillization with heavy prescription tranquillizing the mind by relieving convulsion, arresting sweating controlling nocturnal emission with astringent drugs, hemostasis astringing intestine to stop diarrhea, promoting tissue regeneration and ulcer healing.Control infantile convulsion demented, palpitation with a distress feeling is forgetful, insomnia and dreamful sleep, and spontaneous sweating, seminal emission stranguria with turbid discharge, tells nosebleed and has blood in stool, bleeding not during menses, dysentery proctoptosis, ulcer does not close up for a long time." herbal classic ": " main cough with dyspnea, lets out dysentery pus and blood, and woman is leaked down, the hard knot of lump in the abdomen, children's's steam infantile convulsion." main component: be mainly calcium carbonate, calcium phosphate, also iron content, potassium, sodium, chlorine etc. calmness, hypnosis, anticonvulsant action.
Semen Arecae: bitter in the mouth; Pungent; Warm in nature.Return stomach; Large intestine channel.There is parasite killing, removing mass, sending down the abnormal ascending QI is capable stagnant, and row aquation is wet.Effect.Cure mainly rapid digestion of food and relieve oedema or abdominal distension through diuresis or purgation, kill intestinal volt corpse, proglottid of tapeworm; Except dampness, get round by bribery, sharp nine orifices, relieving restlessness, caking in broken abdomen; Also can control that beriberi, edema, chest pain, dysentery, abdominal distention stomachache, defecation are unfavorable, mental disorder dyspnea with rapid respiration, treat pernicious malaria, resist communicable subtropical diseases." detailed outline ": semen arecae goes out ridge table, the southern regions of the Yunnan Province, i.e. flat the and puckery person of a kind of enlarged abdomen shape in Semen Arecae, not like the good ear of the Semen Arecae long taste of point, so-called pig Semen Arecae person is.Cover the different of also local products, moderns very do not distinguish.Press Liu Xun " ridge table record " cloud, hand over, wide survivor, Semen Arecae on non-oceangoing ship, all semen arecae also, know in that and exhale as Semen Arecae, delicate and old, adopt and real eat it, stay rattan, watt room ash with food to hold up, with the communicable subtropical diseases of dispelling, receive its skin and be used as medicine, the outer black of skin, Intradermal all muscle silk as Cortex cocois radicis (Cocos nucifera L.)." Yunnan note " cloud again, large every of abdomen Semen Arecae has three, 200, when blue or green, cuts open it, with a slice betel leaf and Pulvis concha Mactrae volume with eat it, subtracts astringent taste.See this and one say, semen arecae and Semen Arecae can be general, but the slightly bad ear of force rate Semen Arecae.
Herba Epimedii: kidney invigorating and YANG supporting; Expelling wind and removing dampness; Strong muscle key bone.Impotence and seminal emission; Cold caused by deficiency is sterile; Frequent micturition incontinence; Dyspnea and cough due to deficiency of the kidney; Soreness of the waist and knees; Rheumatic arthralgia; Hemiplegia; The meciless kidney-replenishing of extremity, bone and muscle strengthening, wind-damp dispelling.For impotence and seminal emission, muscles and bones flaccidity is soft, rheumatic arthralgia, numbness contracture; Climacteric hypertension.
Cortex Acanthopancis: acrid in the mouth, hardship, micro-sweet, warm in nature, enter spleen, kidney, heart channel, there is replenishing QI to invigorate the spleen, tonifying the kidney for tranquilization, effect of expelling wind and removing dampness, soft for anemofrigid-damp arthralgia, lumbocrural pain, muscles and bones flaccidity, be slow in action, a little less than body weakness with emaciation, traumatic injury, fracture, edema, beriberi, the uncontrolled urination card such as itch.
Poria: sweet, light, flat.GUIXIN warp, lung meridian, spleen channel, kidney channel.Function: diuretic medicine; Diuretics with the action of eliminating dampness.. " medication heart method ": " sweet with supporing yang, the panacea of dehumidifying is also for Poria, the sharp key of light energy.The flat YANG invigorating of sweet in the mouth, strengthening the spleen is relieved oedema or abdominal distension through diuresis or purgation, the inducing QI of promoting the production of body fluid." modern study shows that the interaction energy many-side that Poria has an enhancing immunity regulates immunologic function.Concoct: be soaked in water, clean, after profit, slightly steam, cut in time skin and piece or cut sheet, dry.Medication taboo: the deficiency of YIN and without damp and hot, deficiency and coldness spermatorrhea, the careful clothes of collapse of QI person.. Collective Notes to the Canon of Materia medica: " Chinese small iris makes for it.Dislike and hold back in vain.Fear Rhizoma Paridis tetraphyllae, Radix Sanguisorbae, Realgar, Radix Gentianae Macrophyllae, Carapax Et Plastrum Testudinis ", " must join book on Chinese herbal medicine ": " collapse of QI, water dry up xerostomia all forbid ".
The Radix Paeoniae Alba: the Radix Paeoniae Alba, the Radix Paeoniae Alba is cool in nature, and bitter in the mouth acid, is slightly cold, and has the easing the affected liver of enriching blood, suppressing the hyperactive liver pain relieving.Yin fluid astringing is received the effects such as antiperspirant, be applicable to fever due to yin deficiency, menoxenia, the breast abdomen pain over the hypochondriac region, extremity contraction anxious, dysentery stomachache, spontaneous sweating, metrorrhagia, have antibacterial, antipyretic, antiinflammatory, increase coronary flow, improve the effect of myocardial nutritional flow, blood vessel dilating, antagonism acute myocardial ischemia, anticoagulant, calmness, analgesia, spasmolytic, antiulcer, adjusting blood glucose with inferior disease paeoniflorin.Radix Paeoniae Alba decoct can suppress dysentery bacterium, streptococcus pneumoniae, escherichia coli, Bacillus typhi, Hemolytic streptococcus, bacillus pyocyaneus etc.
Radix Et Rhizoma Rhei: can attack stagnant; Clearing away damp-heat; Pathogenic fire purging; Removing heat from blood; Blood stasis dispelling; Removing toxic substances cures mainly: excess-heat constipation; The accumulation of heat feeling of stuffiness in chest; Damp-heat dysentery; Jaundice; Gonorrhea; Edema abdominal distention; Dysuria conjunctival congestion; Laryngopharynx swelling and pain; Aphtha of the mouth and tongue; Gastropyretic vomiting; Spit blood; Spitting of blood; Epistaxis; Have blood in stool; Hematuria; Blood-retention; Amenorrhea; The stagnant stomachache of the stasis of blood in puerperal; Lump in the abdomen; Traumatic injury; Pyretic toxicity carbuncle and ulcer; Erysipelas; Scald.
Pericarpium Citri Reticulatae: nature and flavor hardship, pungent, temperature.Return lung, spleen channel.There is regulating qi-flowing for strengthening spleen, the function of drying dampness to eliminate phlegm.Can be used for fullness in the epigastrium and chest, lack of appetite and vomiting, cough with copious phlegm.Therefore Pericarpium Citri Reticulatae has three major types effect, the one, lead cold-evil in the heart, two broken stagnant gas, three strengthening the spleen stomaches.This three greatly on, Main Function is row QI of the spleen and stomach.The main transmitting and distributing the fluids of taste, therefore QI of the spleen and stomach capablely can dry, spleen invigorating, reduce phlegm, therefore can say again, Pericarpium Citri Reticulatae temperature can be supported spleen, pungent can being amusing, bitter can spleen invigorating.Due to the main row QI of the spleen and stomach of Pericarpium Citri Reticulatae, taste are located in middle Jiao, and middle Jiao's gas is current, and the gas of three warmers is also sprung up thereupon.Three warmers are the organ in charge of water circulation, and current water liquid, accompanies with wetting phase; Again for hiding mansion outside mansion, the upper and heart, lung, lower and liver, kidney.So the effect of Pericarpium Citri Reticulatae can wide and all Zang Fu, spread all over whole body wet.Say from lung, pungent loose lung qi, hardship is let out lung qi, and temperatureization cold can be controlled abundant expectoration cough with asthma, and gas is stopped up food and is stopped; Say from the heart, pungent happy gas, hardship is let out heart-fire, and warm removing dampness is turbid, can control irritable feverish sensation in the chest, and the implication sound of vomiting is smelly; Say from liver, pungent loose stagnation of liver-QI, liver-fire falls in hardship, warming for eliminaring cold-damp, so its can treating the liver strongly fragrantly has heat, drink is stopped eating stagnant; Say from kidney, pungent profit kidney is dry, and it is wet that hardship is let out kidney, and gentle kidney qi, so it can control life fire deficiency, indigestion.Certainly, all explanations, all with wet relevant with spleen, so its property of medicine effect performance leeway is larger, all can be used in general activating QI to eliminate phlegm side.As Li Shizhen (1518-1593 A.D.) is said: " Pericarpium Citri tangerinae hardship can be let out can be dry, pungent energy loose can and, it controls all kinds of diseases and ailments, always gets the merit of its dampness of regulating the flow of vital energy.
Bulbus Allii: warm in nature, acrid in the mouth, flat, enters spleen, stomach, lung meridian, has removing toxic substances parasite killing, reducing swelling and alleviating pain, effect of antidiarrheal dysentery relieving, cures mainly swollen ulcer drug, white bald tinea skin ulcer, dysentery is had loose bowels, pulmonary tuberculosis pertussis, ascarid pinworm, eating accumulation, coldness and pain in the epigastrium, the cards such as edema distension.
Radix Angelicae Sinensis: be applicable to all cards of blood deficiency; Menoxenia; Amenorrhea; Dysmenorrhea; Lump in the abdomen knot is poly-; Metrorrhagia; Asthenia cold abdominalgia; Flaccidity syndrome and arthralgia syndrome; Numbness of the skin; Dryness of the intestine dyschezia; Heavy after bloody dysentery; Ulcer sores; Injury from falling down.1. effect: with controlling apoplexy syncope, spit out white foams, puerperal paralysis.1. oxygen lack resistant function; 2. regulate body's immunity, there is antitumaous effect; 3. cosmetology effect; 4. the effect of invigorating blood circulation of enriching blood; 5. antibacterial, arteriosclerosis effect.
Radix Codonopsis: Chinese medicine Radix Codonopsis is campanulaceae herbaceos perennial Radix Codonopsis, element flower Radix Codonopsis, radix codonpsis tangshen and the root that belongs to various plants together thereof.Radix Codonopsis is the conventional traditional tonic of China, and the Radix Codonopsis that produce ancient times taking area, Shangdang, Shanxi, as top grade, has invigorating the spleen and replenishing QI, effect of spleen invigorating lung benefiting.Modern study, Radix Codonopsis, containing various saccharides, phenols, sterol, volatile oil, scutellarein glucosid, Saponin and Alkaloid, has enhancing immunity, blood vessel dilating, blood pressure lowering, improves microcirculation, strengthens the effects such as hemopoietic function.In addition leukopenia chemotherapy radiotherapy being caused has castering action.Radix Codonopsis has invigorating the spleen and replenishing QI, effect of spleen invigorating lung benefiting.For deficiency of the spleen and lung, the cardiopalmus of breathing hard, anorexia and loose stool, dyspnea due to deficiency cough, interior-heat is quenched one's thirst etc." Bencao Congxin " recorded: " invigorating the spleen and replenishing QI and taste, relieving thirst and restlessness.A little less than middle feeble QI, mend in order to adjust, very smooth and proper." impact on digestive system: adjust the key medicine that gastrointestinal motility function Radix Codonopsis is invigorating the spleen and replenishing QI, can correct the gastrointestinal motility dysfunction of pathological state.By the method for chronic heeling-in stomach electrode, observing Radix Codonopsis water decoction-alcohol sedimentation liquid has regulating action to rat stomach basic electrical rhythm disorder under stress state, and the stomach motion that can partly cause anti-stress increases and rapid gastric emptying.Asiabell preparation intravenous injection is wriggled to normal rat stomach or is all had inhibitory action with the gastric peristalsis that neostigmine has strengthened, and shows as that peristalsis amplitude reduces, frequency deceleration.Radix Codonopsis decocting liquid can improve mice III degree and scald hindgut power function obstacle, significantly improves intestinal propulsion rate.Radix Codonopsis liquid has and suppresses and excited two kinds of effects isolated guinea pig ileum, can make tensile force of ileum raise or first fall rear liter, Frequency downshift, and can maintain the long period, and acetylcholine and 5-HT are caused to ileum contraction has obvious antagonism.Antiulcer action Radix Codonopsis water decoction-alcohol sedimentation liquid to stress type, Experimental Gastric Ucler all has preventive and therapeutic action due to pyloric ligation ulcers, indometacin or aspirin.
The Rhizoma Atractylodis Macrocephalae: sweet in the mouth, hardship, warm in nature, enter spleen, stomach warp, there is spleen reinforcing promoting the circulation of QI, dampness diuretic, strengthening superficial resistance to stop perspiration, effect that activating the spleen is moisturized, cures mainly the feeling of fullness diarrhoea due to dysfunction of the spleen in transportation, QI failing to transform into body fluid, phlegm retention edema; The vexed lazy speech of deficiency of QI in middle-JIAO, metrorrhagia and metrostaxis, proctoptosis with chronic dysentery; The cards such as solid in the playing of deficiency of the spleen causing weakness of QI, sweating due to debility spontaneous perspiration, the Rhizoma Atractylodis Macrocephalae can promote gastric secretion, strengthens the Absorption of small intestinal, and gastrointestinal function is had to regulating action.
Fructus Aurantii: dispelling the stagnated QI, row expectorant, removing food stagnancy.Control chest and diaphragm expectorant stagnant, the feeling of stuffiness in chest, coerce swollen, food stagnation, eructation, vomiting, heavy after dysentery, proctoptosis, uterine prolapse.1. " property of medicine opinion ": control rubella all over, in flesh, dislike and itch as numb bean, main hemorrhoidal hamorrhage haemorrhoids, stagnation of QI in chest and abdomen, the swollen void of two sides of body, pass diaphragm is congested.2. " Japan hanako materia medica ": spleen benefiting and stimulating the appetite, adjust the five internal organs, the therapeutic method to keep the adverse QI flowing downwards, preventing or arresting vomiting is contrary, expectorant.Control regurgitation, cholera dysentery, helps digestion, broken crux mass beside the umbilicus, and five types of dysphagia, except wind improving eyesight and lung qi edema, sharp intestine and small intestine, skin is itched.Swollen can the processing of hemorrhoid pressed.3. " Kaibao Bencao ": the main air paralysis of itching, easing joint movement, consumptive disease cough, back of the body arm is bored and listless, and the loose knot, chest and diaphragm expectorant of staying is stagnant, relieve oedema or abdominal distension through diuresis or purgation, full, the large hemorrhoidal hamorrhage of relieving distension, peace stomach, only wind is bitterly.4. " pearl sac ": dispelling the stagnated QI, let out gas unfavorable in lung.5. " medicine origin ": " curing mainly secret formula " cloud, broken hardness in the epigastrium painful abdominal mass, profit is gas in the heart, reduces phlegm, and 6. help digestion " detailed outline ": control tenesmus.
Cortex Magnoliae Officinalis: be dry dried bark, root bark and the branch skin of Magnoliacea plant Cortex Magnoliae Officinalis or magnolia officinalis rehd.et wils.var.biloba rehd.et wils..Main product is in the ground such as Sichuan, Hubei.Strip 4 ~ June, root bark and branch skin Directly Dried in Shadow, and dried bark is put the dark and damp place of banking up after micro-boiling in boiling water, and " diaphoresis " during to inner surface skin puce or sepia, steams soft taking-up, is rolled into tubular, dry.Shredding, processed with Rhizoma Zingiberis Recens is used.Bitter; Pungent; Warm in nature.Removing dampness by means of aromatics Chinese medicine, cures mainly: stagnation of QI due to dyspepsia; Abdominal distention constipation; Retention of dampness in middle-JIAO, gastral cavity painful abdominal mass is vomited and diarrhoea; Expectorant is stopped up QI rising in reverse order; Fullness in the chest is breathed with cough.
Fructus Forsythiae: Fructus Forsythiae, green grass or young crops stick up, fall to sticking up, Huang Qidan etc., fruit medicine.Fructus Forsythiae is the Chinese medicine of heat-clearing and toxic substances removing, cures mainly calentura from the beginning of, anemopyretic cold, and heating is vexed, laryngopharynx swelling and pain, acute nephritis etc.Fructus Forsythiae first leaf in early spring is bloomed, and the flowers are in blossom, and fragrance is light gorgeous, and full branch is golden yellow, gorgeous lovely, is good sight flowering shrub in early spring.Hardship, is slightly cold.Return lung, the heart, gallbladder meridian.Fructus Forsythiae has broad-spectrum antibacterial action, and staphylococcus aureus, Hayes dysentery bacterium are had to very strong inhibitory action, and other pathogenic bacterium, influenza virus, fungus are had to certain inhibitory action.There is antiinflammatory action.The contained oleanolic acid of this product has heart tonifying, diuresis and hypotensive activity, and Citrin can reduce vascular permeability and fragility, prevents haemolysis.Decoct has the town effect of telling, anti-liver injury effect.Heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, dispelling wind and heat pathogens.Cure mainly carbuncle sore tumefacting virus, sucutaneous nodule scrofula, affection due to external wind and heat, epidemic febrile disease is from the beginning of, puckery pain of pyretic stranguria etc.
Fructus Gardeniae: pathogenic fire purging relieving restlessness; Clearing away heat-damp and promoting diuresis; Removing pathogenic heat from blood and toxic substance from the body; Fructus Gardeniae Preparatus: cooling blood for hemostasis.Cure mainly: calentura is vexed; Liver-fire conjunctival congestion; Headache; Jaundice due to damp-heat; Stranguria; Dysentery hematuria; Aphtha of the mouth and tongue; Sore swollen toxin; Sprain and swell and ache.1. calentura is vexed.This product bitter cold is fallen clearly, can rush down clearly three warmers pathogenic fire, eliminating heart-fire and relieving restlessness, for controlling the key medicine that calentura is vexed, restlessness is not peaceful, can with the same use of Semen Sojae Preparatum, as Decoction of Capejasmine and Fermented Soybean treatise on Febrile Diseases; If join Radix Scutellariae, Rhizoma Coptidis, Cortex Phellodendri etc., the available calentura fire-toxin of controlling is flourishing, and all heat of three warmers and see that high heat is irritated, unconsciousness and delirium person, as Rhizoma Coptidis toxic materials clearing away decoction " outer Fructus Gardeniae platform is secret to be wanted ".2. jaundice due to damp-heat.These product have effect of sharp clearly part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels dampness-heat in the liver and gallbladder, the jaundice of available treating the liver gallbladder retention and fumigation of damp-heat inside the body, oliguria with reddish urine person.3. blood strangury and dry pain.The kind clearing away damp-heat from lower-JIAO of these product is and treating stranguria, and clearing away heat and cooling blood is with hemostasis, therefore can control blood strangury and dry pain or pyretic stranguria card.
Massa Medicata Fermentata: nature and flavor hardship, temperature.1. " property of medicine is examined ": " micro-bitter fragrant sweet." 2. " detailed outline is picked up any lost article from the road ": " and sweet light, delicate fragrance." enter spleen, stomach, large intestine channel.After flour, wheat bran and multi-medicament are mixed, the herbal leaven forming through fermentation.Can strengthening the spleen to promote digestion, regulating QI to expel dampness, induces sweat.The food feeling of stuffiness in chest that cures the wound, stomachache is vomited and diarrhoea, dysentery, headache due to common cold, children's hinder hungry lose full.In Massa Medicata Fermentata, there is yeast.Its composition has volatile oil, glycoside, fatty oil and vitamin B etc." Bencao Jingshu " said: " ancients use bent, the song brewing alcoholic beverages, and the sweet temperature of its abnormal smells from the patient, the special food stagnation removing of property, the stagnant gas of row taste, loose internal organs are air-cooled.Massa Medicata Fermentata is that descendant specially makes, and with hyoscine, doubles in distillers yeast ".
Fructus Hordei Germinatus: nature and flavor are sweet is flat.Return spleen, stomach warp, Liver Channel.Have promote qi circulation digestion promoting, spleen benefiting and stimulating the appetite, moves back effect of newborn relieving distension.Cure mainly food stagnation and do not disappear, abdominal distention, insufficiency of the spleen lack of appetite, newborn antiperspirant smoulders, distending pain of the breast, women's ablactation.Fructus Hordei Germinatus can be used for stagnation of QI due to depression of the liver, breast side of body feeling of distension and oppression, and liver spleen is not each, and belch is eaten less and is waited card, often and the compatibility such as Fructus Citri Sarcodactylis, to increase the effect of its soothing liver-QI stomach function regulating.Weakness of the spleen and stomach, transporting is unable, and causes the food stagnation person that do not disappear, and can be equal to use with Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, Pericarpium Citri Reticulatae, to increase the power of strengthening the spleen to promote digestion.
Comb leaf Artemisia: cure mainly: micro-hardship, puckery, cold.Clearing liver-gallbladder, anti-inflammatory analgetic.Cure mainly acute icterohepatitis, headache, dizziness.
Radix Malvae sylvestris: nature and flavor: salty, cold.Cure mainly: clearing away heat-damp and promoting diuresis, regulating the flow of QI to relieve constipation.Cure mainly defecation not smooth, tuberculous lymphadenitis, leukorrhagia, periumbilical pain.
Herba boeae clarkeanae: nature and flavor: hardship, cold.Cure mainly: antiinflammatory, removing heat from blood, synthetism.For bronchitis, tonsillitis, lung-heat hemoptysis, skin ulcer, furuncle, mastitis, proctoptosis, hemorrhoid, tumor, traumatic hemorrhage, burn and scald, fracture.
Folium Cremastrae appendiculatae: nature and flavor: hardship, cool.Gui Jing: liver, heart channel.Cure mainly: heat-clearing and toxic substances removing, main swollen ulcer drug.
Herba Violae philippicae: nature and flavor: sweet, cold.Cure mainly: heat clearing away, removing toxic substances, eliminating stagnation.Control furuncle, scrofula.
Largeleaf Gymnema: nature and flavor: hardship, flat.Cure mainly: heat-clearing and toxic substances removing, wind-expelling pain-stopping.For rheumatic arthritis, carbuncle furuncle and phyma poison, venom.
Sputum Anseris domestica: nature and flavor: salty; Flat.Gui Jing: lung meridian.Cure mainly: softening hardness and disperse swelling.The main awn of wheat or fish spicule bone stuck in the throat; Thrush.
Sesarmae dehaani: nature and flavor: salty in the mouth; Cold in nature.Gui Jing: spleen channel.Cure mainly: heat-clearing and toxic substances removing; Removing damp to relieve itching.Main carbuncle sore tumefacting virus; Exudative dermatitis pruritus.
Colysis bonii Ching.: nature and flavor: micro-hardship; Puckery; Cool.Gui Jing: enter liver, kidney, bladder three warps.Cure mainly: blood circulation promoting and blood stasis dispelling; Clearing away heat and promoting diuresis.Main traumatic injury; Little example is drenched the puckery pain of drop.
Herba Phlomidis Tuberosae: nature and flavor: " plateau Chinese herbal treatment handbook ": " warm in nature, mildly bitter flavor, slightly poisonous." return through: " plateau Chinese herbal treatment handbook ": " enters liver, spleen two warps." curing mainly: 1. " plateau Chinese herbal treatment handbook ": " removing toxic substances, drives prunus mume (sieb.) sieb.et zucc.." the 2. Inner Mongol " a collection of selected materials of Chinese herbal medicine new therapy that combines both Chinese and Western medical practices data ": " controls menoxenia."
Herba cirsii esculenti: nature and flavor: sweet, cool.Cure mainly: dissipating blood stasis for subsidence of swelling, evacuating pus and expelling toxin by reinforcing QI and blood, hemostasis.Control pulmonary abscess, sore and toxic, dermatosis, liver-heat is various hemorrhage.
Peng Lai Pueraria lobota: cure mainly: expelling wind and activating blood circulation.Cure mainly arthritis; Wound hemorrhage is controlled in external.
Pueraria lobota Bud: nature and flavor: sweet, flat.Cure mainly: tonifying five ZANG-organs, reuniting the fractured tendons and bones, longue meat, edible fruit, joint is ached, traumatic injury: root bark is mashed deposited affected part with sweet wine.
Herba Cayatiae Japonicae: nature and flavor: picric acid, cold.1. Tang Materia Medica: " sour in the mouth hardship, cold, nontoxic." 2. 《 Lv Cliff rock book on Chinese herbal medicine ": " sweet, cold, nontoxic." 3. " Kweiyang medicinal herbs among the people ": " toil, flat, nontoxic." returning through " east, Fujian book on Chinese herbal medicine ": " enters the heart, liver, stomach three warps." cure mainly: clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling.Control carbuncle, furuncle, mumps, erysipelas, rheumatalgia, jaundice, dysentery, hematuria, nebulousurine.For laryngopharynx swelling and pain, furuncle and phyma, carbuncle, furuncle, dysentery, hematuria, nebulousurine, traumatic injury, venom.1. TAO Hong-Jing: " smash deposited skin ulcer swollen, snakeworm stings place." 2. Tang Materia Medica: " main air is scorchingly hot swollen, You Dan, and snakebite, smashes and applies and drink juice." 3. 《 Lv Cliff rock book on Chinese herbal medicine ": " control carbuncle carbuncle on the back, mash net for catching birds or fish affected part." 4. " detailed outline ": " removing pathogenic heat from blood and toxic substance from the body, diuresis; Root is beaten wine clothes, and furuncle and phyma disappears." 5. " vegetation is side just ": " heat-clearing and toxic substances removing, is coated with sore, the tuberculosis that disappears, nine fictitious gas infectionss.Tonification is deficient." 6. " classification medical herbs ": " removes the wind expectorant that falls apart.Control five kinds of jaundice, sow wind; Be coated with sore." 7. " medicine will is planted in Jiangsu ": " hot water bubble, smoked lower limb can pain relieving.The paralysis of " 8. " Kweiyang medicinal herbs among the people ": " dispelling the wind and dampness pathogens." 9. " Hunan medicine will ": " controls migraine, hemorrhoid." 10. " east, Fujian book on Chinese herbal medicine ": " controls diarrhea of heat type, dysentery."
Drymotaenium miyoshianum (Mak.) Mak.: nature and flavor: sweet; Cool.Gui Jing: liver; Kidney channel.Cure mainly: clearing away heat and relieving the wind syndrome; Invigorate blood circulation.Main infantile convulsion; Impairment caused by overstrain.
Herba Zanthoxyli Myriacanthi: nature and flavor: pungent, micro-hardship, temperature.Cure mainly: expelling wind and removing dampness, promoting blood circulation to remove blood stasis, reducing swelling and alleviating pain.
Carnis cauda Anseris domestica: nature and flavor: pungent; Temperature.Gui Jing: spleen; Stomach; Kidney channel.Cure mainly: tonifying liver.Main " solar corona ": " control Ting ear and deaf, receive it; Also treat brothers chapped.”
The auspicious grass that connects: nature and flavor: bitter, sour, cool.Cure mainly: heat-clearing and toxic substances removing.
Herba Scorzonerae Divaricatae: nature and flavor: " Inner Mongol Chinese herbal medicine ": " toil, cold." cure mainly: control furuncle swollen, verruca vulgaris.1. " Inner Mongol Chinese herbal medicine ": " heat-clearing and toxic substances removing.Control furuncle and malignant sore, closely have examination to be used for the treatment of gastric cancer, thyroid carcinoma." 2. " Deserts in China area medicinal plants ": " dispersing swelling and dissipating binds."
Rhizoma Smilacis: nature and flavor: 1. " Traditional Chinese Medicine in Sichuan will ": " hardship, flat, nontoxic." 2. " choosing of Yunnan Chinese herbal medicine ": " is sweet light, flat." return through: " Traditional Chinese Medicine in Sichuan will ": " enters liver, stomach, kidney three warps." curing mainly: 1. " Traditional Chinese Medicine in Sichuan will ": " wind-damp dispelling, point pure and impure, sharp joint, separates sore.Dispelling the wind and dampness pathogens pain, waist knee joint arthralgia pain.Stranguria with turbid discharge and syphilis malignant boil." 2. " choosing of Yunnan Chinese herbal medicine ": " expelling wind and removing dampness, treating stranguria, diuretic, antiinflammatory, removing toxic substances.Treating rheumatic arthritis, urinary system infection, chronic gastritis, menoxenia, furuncle."
Wherein, in Chinese medicine additive, the parts by weight of each raw medicinal material are preferably: comb leaf Artemisia 15-35 weight portion, Radix Malvae sylvestris 10-30 weight portion, Herba boeae clarkeanae 10-25 weight portion, Rhizoma Atractylodis 15-35 weight portion, Folium Cremastrae appendiculatae 10-35 weight portion, Concha Ostreae 10-30 weight portion, Herba Violae philippicae 15-35 weight portion, Os Draconis 10-30 weight portion, Semen Arecae 15-35 weight portion, Herba Epimedii 15-35 weight portion, Cortex Acanthopancis 10-30 weight portion, Poria 15-35 weight portion, Radix Paeoniae Alba 10-30 weight portion, Radix Et Rhizoma Rhei 15-35 weight portion, Pericarpium Citri Reticulatae 10-30 weight portion, Largeleaf Gymnema 10-30 weight portion, Bulbus Allii 15-35 weight portion, Sputum Anseris domestica 10-30 weight portion, Radix Angelicae Sinensis 15-35 weight portion, Radix Codonopsis 10-30 weight portion, Rhizoma Atractylodis Macrocephalae 15-35 weight portion, Fructus Aurantii 10-30 weight portion, Cortex Magnoliae Officinalis 10-30 weight portion, Fructus Forsythiae 15-30 weight portion, Fructus Gardeniae 10-30 weight portion, crab Qi 15-35 weight portion, Massa Medicata Fermentata 10-30 weight portion, Colysis bonii Ching. 15-35 weight portion, Fructus Hordei Germinatus 10-30 weight portion, Herba Phlomidis Tuberosae 15-35 weight portion, Herba cirsii esculenti 10-30 weight portion, Peng Lai Pueraria lobota 15-35 weight portion, Pueraria lobota Bud 10-30 weight portion, Herba Cayatiae Japonicae 15-35 weight portion and Drymotaenium miyoshianum (Mak.) Mak. 10-30 weight portion.
Wherein, in Chinese medicine additive, the parts by weight of each raw medicinal material can also be preferably: comb leaf Artemisia 15-25 weight portion, Radix Malvae sylvestris 15-30 weight portion, Herba boeae clarkeanae 15-25 weight portion, Rhizoma Atractylodis 15-30 weight portion, Folium Cremastrae appendiculatae 15-35 weight portion, Concha Ostreae 15-30 weight portion, Herba Violae philippicae 15-30 weight portion, Os Draconis 15-30 weight portion, Semen Arecae 15-30 weight portion, Herba Epimedii 15-30 weight portion, Cortex Acanthopancis 15-30 weight portion, Poria 15-30 weight portion, Radix Paeoniae Alba 15-30 weight portion, Radix Et Rhizoma Rhei 15-30 weight portion, Pericarpium Citri Reticulatae 15-30 weight portion, Largeleaf Gymnema 15-30 weight portion, Bulbus Allii 15-30 weight portion, Sputum Anseris domestica 15-30 weight portion, Radix Angelicae Sinensis 15-30 weight portion, Radix Codonopsis 15-30 weight portion, Rhizoma Atractylodis Macrocephalae 15-30 weight portion, Fructus Aurantii 15-30 weight portion, Cortex Magnoliae Officinalis 15-25 weight portion, Fructus Forsythiae 15-25 weight portion, Fructus Gardeniae 15-30 weight portion, crab Qi 15-30 weight portion, Massa Medicata Fermentata 15-30 weight portion, Colysis bonii Ching. 15-30 weight portion, Fructus Hordei Germinatus 15-30 weight portion, Herba Phlomidis Tuberosae 15-30 weight portion, Herba cirsii esculenti 10-25 weight portion, Peng Lai Pueraria lobota 15-30 weight portion, Pueraria lobota Bud 15-30 weight portion, Herba Cayatiae Japonicae 15-30 weight portion and Drymotaenium miyoshianum (Mak.) Mak. 15-30 weight portion.
Wherein, in Chinese medicine additive, the parts by weight of each raw medicinal material can be preferably again: comb leaf Artemisia 18 weight portions, Radix Malvae sylvestris 17 weight portions, Herba boeae clarkeanae 25 weight portions, Rhizoma Atractylodis 25 weight portions, Folium Cremastrae appendiculatae 30 weight portions, Concha Ostreae 18 weight portions, Herba Violae philippicae 22 weight portions, Os Draconis 25 weight portions, Semen Arecae 20 weight portions, Herba Epimedii 28 weight portions, Cortex Acanthopancis 18 weight portions, Poria 17 weight portions, the Radix Paeoniae Alba 22 weight portions, Radix Et Rhizoma Rhei 25 weight portions, Pericarpium Citri Reticulatae 22 weight portions, Largeleaf Gymnema 17 weight portions, Bulbus Allii 20 weight portions, Sputum Anseris domestica 25 weight portions, Radix Angelicae Sinensis 18 weight portions, Radix Codonopsis 25 weight portions, the Rhizoma Atractylodis Macrocephalae 19 weight portions, Fructus Aurantii 25 weight portions, Cortex Magnoliae Officinalis 17 weight portions, Fructus Forsythiae 22 weight portions, Fructus Gardeniae 28 weight portions, crab Qi 18 weight portions, Massa Medicata Fermentata 22 weight portions, Colysis bonii Ching. 25 weight portions, Fructus Hordei Germinatus 18 weight portions, Herba Phlomidis Tuberosae 17 weight portions, Herba cirsii esculenti 20 weight portions, Peng Lai Pueraria lobota 22 weight portions, Pueraria lobota Bud 25 weight portions, Herba Cayatiae Japonicae 28 weight portions and Drymotaenium miyoshianum (Mak.) Mak. 19 weight portions.
Wherein, in Chinese medicine additive, the parts by weight of each raw medicinal material can be preferably: comb leaf Artemisia 15-35 weight portion, Radix Malvae sylvestris 10-30 weight portion, Herba boeae clarkeanae 10-25 weight portion, Rhizoma Atractylodis 15-35 weight portion, Folium Cremastrae appendiculatae 10-35 weight portion, Concha Ostreae 10-30 weight portion, Herba Violae philippicae 15-35 weight portion, Os Draconis 10-30 weight portion, Semen Arecae 15-35 weight portion, Herba Epimedii 15-35 weight portion, Cortex Acanthopancis 10-30 weight portion, Poria 15-35 weight portion, Radix Paeoniae Alba 10-30 weight portion, Radix Et Rhizoma Rhei 15-35 weight portion, Pericarpium Citri Reticulatae 10-30 weight portion, Largeleaf Gymnema 10-30 weight portion, Bulbus Allii 15-35 weight portion, Sputum Anseris domestica 10-30 weight portion, Radix Angelicae Sinensis 15-35 weight portion, Radix Codonopsis 10-30 weight portion, Rhizoma Atractylodis Macrocephalae 15-35 weight portion, Fructus Aurantii 10-30 weight portion, Cortex Magnoliae Officinalis 10-30 weight portion, Fructus Forsythiae 15-30 weight portion, Fructus Gardeniae 10-30 weight portion, crab Qi 15-35 weight portion, Massa Medicata Fermentata 10-30 weight portion, Colysis bonii Ching. 15-35 weight portion, Fructus Hordei Germinatus 10-30 weight portion, Herba Phlomidis Tuberosae 15-35 weight portion, Herba cirsii esculenti 10-30 weight portion, Peng Lai Pueraria lobota 15-35 weight portion, Pueraria lobota Bud 10-30 weight portion, Herba Cayatiae Japonicae 15-35 weight portion, Drymotaenium miyoshianum (Mak.) Mak. 10-30 weight portion, Herba Zanthoxyli Myriacanthi 15-35 weight portion, Carnis cauda Anseris domestica 10-25 weight portion, the careless 10-20 weight portion of auspicious company, Herba Scorzonerae Divaricatae 15-35 weight portion and Rhizoma Smilacis 10-30 weight portion.
Wherein, in Chinese medicine additive, the parts by weight of each raw medicinal material can also be preferably: comb leaf Artemisia 25 weight portions, Radix Malvae sylvestris 22 weight portions, Herba boeae clarkeanae 18 weight portions, Rhizoma Atractylodis 25 weight portions, Folium Cremastrae appendiculatae 17 weight portions, Concha Ostreae 28 weight portions, Herba Violae philippicae 17 weight portions, Os Draconis 22 weight portions, Semen Arecae 20 weight portions, Herba Epimedii 25 weight portions, Cortex Acanthopancis 28 weight portions, Poria 22 weight portions, the Radix Paeoniae Alba 19 weight portions, Radix Et Rhizoma Rhei 18 weight portions, Pericarpium Citri Reticulatae 20 weight portions, Largeleaf Gymnema 27 weight portions, Bulbus Allii 19 weight portions, Sputum Anseris domestica 28 weight portions, Radix Angelicae Sinensis 18 weight portions, Radix Codonopsis 25 weight portions, the Rhizoma Atractylodis Macrocephalae 28 weight portions, Fructus Aurantii 25 weight portions, Cortex Magnoliae Officinalis 18 weight portions, Fructus Forsythiae 20 weight portions, Fructus Gardeniae 22 weight portions, crab Qi 25 weight portions, Massa Medicata Fermentata 28 weight portions, Colysis bonii Ching. 18 weight portions, Fructus Hordei Germinatus 28 weight portions, Herba Phlomidis Tuberosae 17 weight portions, Herba cirsii esculenti 25 weight portions, Peng Lai Pueraria lobota 27 weight portions, Pueraria lobota Bud 25 weight portions, Herba Cayatiae Japonicae 18 weight portions, Drymotaenium miyoshianum (Mak.) Mak. 27 weight portions, Herba Zanthoxyli Myriacanthi 20 weight portions, Carnis cauda Anseris domestica 22 weight portions, careless 20 weight portions of auspicious company, Herba Scorzonerae Divaricatae 30 weight portions and Rhizoma Smilacis 28 weight portions.
Wherein, in Chinese medicine additive, the parts by weight of each raw medicinal material can be preferably again: comb leaf Artemisia 15 weight portions, Radix Malvae sylvestris 30 weight portions, Herba boeae clarkeanae 25 weight portions, Rhizoma Atractylodis 30 weight portions, Folium Cremastrae appendiculatae 35 weight portions, Concha Ostreae 30 weight portions, Herba Violae philippicae 28 weight portions, Os Draconis 25 weight portions, Semen Arecae 28 weight portions, Herba Epimedii 30 weight portions, Cortex Acanthopancis 20 weight portions, Poria 30 weight portions, the Radix Paeoniae Alba 28 weight portions, Radix Et Rhizoma Rhei 28 weight portions, Pericarpium Citri Reticulatae 22 weight portions, Largeleaf Gymnema 18 weight portions, Bulbus Allii 22 weight portions, Sputum Anseris domestica 25 weight portions, Radix Angelicae Sinensis 18 weight portions, Radix Codonopsis 25 weight portions, the Rhizoma Atractylodis Macrocephalae 28 weight portions, Fructus Aurantii 27 weight portions, Cortex Magnoliae Officinalis 25 weight portions, Fructus Forsythiae 22 weight portions, Fructus Gardeniae 30 weight portions, crab Qi 22 weight portions, Massa Medicata Fermentata 19 weight portions, Colysis bonii Ching. 25 weight portions, Fructus Hordei Germinatus 18 weight portions, Herba Phlomidis Tuberosae 28 weight portions, Herba cirsii esculenti 25 weight portions, Peng Lai Pueraria lobota 19 weight portions, Pueraria lobota Bud 27 weight portions, Herba Cayatiae Japonicae 17 weight portions, Drymotaenium miyoshianum (Mak.) Mak. 22 weight portions, Herba Zanthoxyli Myriacanthi 25 weight portions, Carnis cauda Anseris domestica 20 weight portions, careless 17 weight portions of auspicious company, Herba Scorzonerae Divaricatae 28 weight portions and Rhizoma Smilacis 22 weight portions.
In order better to realize foregoing invention object, the present invention also provides the preparation method of the Chinese medicine additive for the treatment of pig pica, and described preparation method comprises the following steps:
Step 1, take all raw medicinal materials according to parts by weight, and be ground into 40 order-60 object powder;
Step 2, above-mentioned gained powder is carried out to charcoal fry 1.0-2.5 hour, adding subsequently with respect to mixture quality 2-4 determining alcohol is doubly 75%-85% alcoholic solution, and heating and refluxing extraction 4.5-7 hour obtains the first extracting solution, filters, and obtains the first filtrate; It is 65%-90% alcoholic solution that filtering residue adds with respect to its quality 2-5 determining alcohol doubly again, heating and refluxing extraction 1.5-3 hour, obtains the second extracting solution, filters, obtain the second filtrate, the first filtrate and the second filtrate are merged, be uniformly mixed, concentrating under reduced pressure, remove ethanol, obtain dry mastic, adopt subsequently pulverizer that dry gained mastic is pulverized, grinding particle size 270 order-400 orders, obtain pulverous described Chinese medicine additive.
Embodiment 1 Chinese medicine additive 1
The embodiment of the present invention provides a kind of Chinese medicine additive for the treatment of pig pica, is made up of the raw medicinal material of following parts by weight: comb leaf Artemisia 18 weight portions, Radix Malvae sylvestris 17 weight portions, Herba boeae clarkeanae 25 weight portions, Rhizoma Atractylodis 25 weight portions, Folium Cremastrae appendiculatae 30 weight portions, Concha Ostreae 18 weight portions, Herba Violae philippicae 22 weight portions, Os Draconis 25 weight portions, Semen Arecae 20 weight portions, Herba Epimedii 28 weight portions, Cortex Acanthopancis 18 weight portions, Poria 17 weight portions, the Radix Paeoniae Alba 22 weight portions, Radix Et Rhizoma Rhei 25 weight portions, Pericarpium Citri Reticulatae 22 weight portions, Largeleaf Gymnema 17 weight portions, Bulbus Allii 20 weight portions, Sputum Anseris domestica 25 weight portions, Radix Angelicae Sinensis 18 weight portions, Radix Codonopsis 25 weight portions, the Rhizoma Atractylodis Macrocephalae 19 weight portions, Fructus Aurantii 25 weight portions, Cortex Magnoliae Officinalis 17 weight portions, Fructus Forsythiae 22 weight portions, Fructus Gardeniae 28 weight portions, crab Qi 18 weight portions, Massa Medicata Fermentata 22 weight portions, Colysis bonii Ching. 25 weight portions, Fructus Hordei Germinatus 18 weight portions, Herba Phlomidis Tuberosae 17 weight portions, Herba cirsii esculenti 20 weight portions, Peng Lai Pueraria lobota 22 weight portions, Pueraria lobota Bud 25 weight portions, Herba Cayatiae Japonicae 28 weight portions and Drymotaenium miyoshianum (Mak.) Mak. 19 weight portions.
Chinese medicine additive makes by following preparation method:
Step 1, take all raw medicinal materials according to parts by weight, and be ground into 55 object powder;
Step 2, by above-mentioned gained powder carry out charcoal fry 2.5 hours, adding subsequently with respect to the determining alcohol of 3 times of mixture qualities is 85% alcoholic solution, heating and refluxing extraction 5 hours, obtain the first extracting solution, filter, obtain the first filtrate; It is 85% alcoholic solution that filtering residue adds with respect to the determining alcohol of 4 times of its quality again, heating and refluxing extraction 2 hours, obtains the second extracting solution, filters, obtain the second filtrate, the first filtrate and the second filtrate are merged, be uniformly mixed, concentrating under reduced pressure, remove ethanol, obtain dry mastic, adopt subsequently pulverizer that dry gained mastic is pulverized, grinding particle size 350 orders, obtain pulverous described Chinese medicine additive.
Embodiment 2 Chinese medicine additive 2
The embodiment of the present invention provides a kind of Chinese medicine additive for the treatment of pig pica, is made up of the raw medicinal material of following parts by weight: comb leaf Artemisia 25 weight portions, Radix Malvae sylvestris 22 weight portions, Herba boeae clarkeanae 18 weight portions, Rhizoma Atractylodis 25 weight portions, Folium Cremastrae appendiculatae 17 weight portions, Concha Ostreae 28 weight portions, Herba Violae philippicae 17 weight portions, Os Draconis 22 weight portions, Semen Arecae 20 weight portions, Herba Epimedii 25 weight portions, Cortex Acanthopancis 28 weight portions, Poria 22 weight portions, the Radix Paeoniae Alba 19 weight portions, Radix Et Rhizoma Rhei 18 weight portions, Pericarpium Citri Reticulatae 20 weight portions, Largeleaf Gymnema 27 weight portions, Bulbus Allii 19 weight portions, Sputum Anseris domestica 28 weight portions, Radix Angelicae Sinensis 18 weight portions, Radix Codonopsis 25 weight portions, the Rhizoma Atractylodis Macrocephalae 28 weight portions, Fructus Aurantii 25 weight portions, Cortex Magnoliae Officinalis 18 weight portions, Fructus Forsythiae 20 weight portions, Fructus Gardeniae 22 weight portions, crab Qi 25 weight portions, Massa Medicata Fermentata 28 weight portions, Colysis bonii Ching. 18 weight portions, Fructus Hordei Germinatus 28 weight portions, Herba Phlomidis Tuberosae 17 weight portions, Herba cirsii esculenti 25 weight portions, Peng Lai Pueraria lobota 27 weight portions, Pueraria lobota Bud 25 weight portions, Herba Cayatiae Japonicae 18 weight portions, Drymotaenium miyoshianum (Mak.) Mak. 27 weight portions, Herba Zanthoxyli Myriacanthi 20 weight portions, Carnis cauda Anseris domestica 22 weight portions, careless 20 weight portions of auspicious company, Herba Scorzonerae Divaricatae 30 weight portions and Rhizoma Smilacis 28 weight portions.
Chinese medicine additive makes by following preparation method:
Step 1, take all raw medicinal materials according to parts by weight, and be ground into 60 object powder;
Step 2, by above-mentioned gained powder carry out charcoal fry 2.5 hours, adding subsequently with respect to the determining alcohol of 4 times of mixture qualities is 75% alcoholic solution, heating and refluxing extraction 4.5 hours, obtain the first extracting solution, filter, obtain the first filtrate; It is 90% alcoholic solution that filtering residue adds with respect to the determining alcohol of 5 times of its quality again, heating and refluxing extraction 3 hours, obtains the second extracting solution, filters, obtain the second filtrate, the first filtrate and the second filtrate are merged, be uniformly mixed, concentrating under reduced pressure, remove ethanol, obtain dry mastic, adopt subsequently pulverizer that dry gained mastic is pulverized, grinding particle size 400 orders, obtain pulverous described Chinese medicine additive.
Embodiment 3 Chinese medicine additive 3
The embodiment of the present invention provides a kind of Chinese medicine additive for the treatment of pig pica, is made up of the raw medicinal material of following parts by weight: comb leaf Artemisia 15 weight portions, Radix Malvae sylvestris 30 weight portions, Herba boeae clarkeanae 25 weight portions, Rhizoma Atractylodis 30 weight portions, Folium Cremastrae appendiculatae 35 weight portions, Concha Ostreae 30 weight portions, Herba Violae philippicae 28 weight portions, Os Draconis 25 weight portions, Semen Arecae 28 weight portions, Herba Epimedii 30 weight portions, Cortex Acanthopancis 20 weight portions, Poria 30 weight portions, the Radix Paeoniae Alba 28 weight portions, Radix Et Rhizoma Rhei 28 weight portions, Pericarpium Citri Reticulatae 22 weight portions, Largeleaf Gymnema 18 weight portions, Bulbus Allii 22 weight portions, Sputum Anseris domestica 25 weight portions, Radix Angelicae Sinensis 18 weight portions, Radix Codonopsis 25 weight portions, the Rhizoma Atractylodis Macrocephalae 28 weight portions, Fructus Aurantii 27 weight portions, Cortex Magnoliae Officinalis 25 weight portions, Fructus Forsythiae 22 weight portions, Fructus Gardeniae 30 weight portions, crab Qi 22 weight portions, Massa Medicata Fermentata 19 weight portions, Colysis bonii Ching. 25 weight portions, Fructus Hordei Germinatus 18 weight portions, Herba Phlomidis Tuberosae 28 weight portions, Herba cirsii esculenti 25 weight portions, Peng Lai Pueraria lobota 19 weight portions, Pueraria lobota Bud 27 weight portions, Herba Cayatiae Japonicae 17 weight portions, Drymotaenium miyoshianum (Mak.) Mak. 22 weight portions, Herba Zanthoxyli Myriacanthi 25 weight portions, Carnis cauda Anseris domestica 20 weight portions, careless 17 weight portions of auspicious company, Herba Scorzonerae Divaricatae 28 weight portions and Rhizoma Smilacis 22 weight portions.
Chinese medicine additive makes by following preparation method:
Step 1, take all raw medicinal materials according to parts by weight, and be ground into 40 order object powder;
Step 2, by above-mentioned gained powder carry out charcoal fry 1.0 hours, adding subsequently with respect to the determining alcohol of 4 times of mixture qualities is 80% alcoholic solution, heating and refluxing extraction 7 hours, obtain the first extracting solution, filter, obtain the first filtrate; It is 90% alcoholic solution that filtering residue adds with respect to its quality 2-5 determining alcohol doubly again, heating and refluxing extraction 2.5 hours, obtains the second extracting solution, filters, obtain the second filtrate, the first filtrate and the second filtrate are merged, be uniformly mixed, concentrating under reduced pressure, remove ethanol, obtain dry mastic, adopt subsequently pulverizer that dry gained mastic is pulverized, grinding particle size 380 orders, obtain pulverous described Chinese medicine additive.
Toxicity test
1, cumulative toxicity test report
Select 20 healthy mices, female, male each 10, taking the Chinese medicine additive of the embodiment of the present invention 1 as object, it is first phase that dosage designs every 7 days, each issue dosage is respectively 0.10LD50,0.20LD50,0.25LD50,0.30LD 50,0.40LD50, and the LD 50 female, male mice of this sample is 4000m part/k part BW (five dosage be 500,750,1100,1800,2400m part/k part BW).Within every 7 days, weigh once, adjust dosage, by 0.05ml/10 part BW per os gavage.After 28 days, animal occurs without death condition, off-test, and by ascending-dose, to tested material after 28 days, female, buck all occurs without death condition.Taking the Chinese medicine additive of embodiment 2 and embodiment 3 as object, carry out according to the method described above toxicity test, result is as identical in embodiment 1.
2, acute toxicity test
40 of application NIH mices, SPF level, male and female half and half, body weight 15～20g, carries out acute toxicity test.Mice is divided into two groups at random, and 20 every group, i.e. matched group and administration group, fasting 12 hours before experiment; Chinese medicine additive prepared by embodiments of the invention 1 is dissolved in water, (concentration is 6.75g crude drug/ml, maximum concentration) gavage, gavage volume is that 7ml/kg(is that single-dose dosage is 28.7 crude drugs/kg), matched group gives equivalent normal saline, administration in a day 3 times, delivery time 8 hours, Continuous Observation 14 days after administration, and record toxic reaction and the death toll of mice.Experimental result shows: with matched group comparison, after administration, mice has no notable difference, experiment Continuous Observation 21 days, and mice overall health of patients, diet, drinking-water, body weight gain are all normal.Therefore the acute toxicity of the Chinese medicine additive of the embodiment of the present invention 1 is low, clinical drug safety.Taking the Chinese medicine additive of embodiment 2 and embodiment 3 as object, carry out according to the method described above toxicity test, result is as identical in embodiment 1.
Treatment contrast test:
In May, 2010-2012 year May, there are 400 pigs that suffer from pica, 400 pigs that suffer from pica are divided into 4 groups at random, be respectively embodiment group 1, embodiment group 2, embodiment group 3 and western medicine group, use respectively the Chinese medicine additive 3 of Chinese medicine additive 2, the embodiment 3 of Chinese medicine additive 1, the embodiment 2 of embodiment 1 to treat and conventional medicament is treated, wherein, the dose of embodiment group 1-3 is every every day, in the basal ration of every kilogram, sneaking into 30g Chinese medicine additive, is 10-20 days during treatment; The conventional medicament of western medicine group is selected different food spirit, every every day, adds the different food spirit of 15-30g in the basal ration of every kilogram, every day 1 time, treatment 15-28 days; Blank group is not carried out any treatment.Treatment finishes rear observation three months, records cure rate and the mortality rate of each group of pig, and result is as shown in table 1.
The standard of curative effect evaluation:
(1) cure: tail biting, sting ear, sting rib, suck umbilicus, the phenomenon such as coprophagy, drink urinates, dig earth with the snout, noisy circle, hurdle race, sow infanticide pig, mutually sting bucket, manner uneasiness, appetite weakens, transference cure such as sight fierceness grade;
(2) effective: tail biting, sting ear, sting rib, suck umbilicus, the phenomenon such as coprophagy, drink urinate, dig earth with the snout, noisy circle, hurdle race, sow infanticide pig, mutually sting bucket, manner uneasiness, appetite weakens, sight fierceness etc., and symptom alleviates more than 50%;
(3) invalid: tail biting, sting ear, sting rib, suck umbilicus, the phenomenon such as coprophagy, drink urinate, dig earth with the snout, noisy circle, hurdle race, sow infanticide pig, mutually sting bucket, manner uneasiness, the symptom such as appetite weakens, sight fierceness is without any improvement.
The each experimental group therapeutic effect of table 1 synopsis
Data from table 1: medicine of the present invention is obviously better than western medicine group to the therapeutic effect of the pig that suffers from pica, improve cure rate, reduce mortality rate.
Four groups, table 2 is treated respectively after 10-28 days and is cured and effective number and time comparative example (%)
Known according to the clinical statistics in above table, Chinese medicine provided by the invention has that healing time is short, short treating period, good effect, the feature such as safe, with strong points.
Clinical trial
Animal experiment adopts the design of single factor contrast test, gets 100 3-45 ages in week, body weight is 15-95 ㎏ left and right, suffers from the family pig of pica, male and female half and half, and test is managed and is prevented routinely on pig farm, compiles overbit, anthelmintic and protective inoculation in preliminary trial period.
The phase of just trying is divided into test group (test group is respectively embodiment group 1, embodiment group 2 and embodiment group 3) and matched group, 25 every group at random.Test period is 60 days, and free choice feeding during this time, freely drinks water, and carries out routinely immunity and anthelmintic.
Feed as follows:
Matched group: basal diet;
Test group:
Embodiment group 1: basal diet+1.5% medicine; Said medicine is the Chinese medicine additive 1 that the embodiment of the present invention 1 makes;
Embodiment group 2: basal diet+1.0% medicine; Said medicine is the Chinese medicine additive 2 that the embodiment of the present invention 2 makes;
Embodiment group 3: basal diet+1.8% medicine; Said medicine is the Chinese medicine additive 3 that the embodiment of the present invention 3 makes.
Test period is 60 days, to the pig of embodiment group 1, embodiment group 2, embodiment group 3 and matched group, gathers the empty venous blood of 10mL, gets the mensuration of 2mL heparin anti-coagulating for t lymphocyte subset group (CD3, CD4, CD8) quantity, lymphocyte positive rate.The serum separating is used for measuring interleukin (IL-2), gamma interferon content.Lymphocyte positive rate adopts acid α-naphthyl acetate esterase Determination Staining.IL-2, gamma interferon content are detected by ELISA method, and IL-2, gamma interferon test kit provide by content MARKET company of the U.S..Adopt the U.S. EPICS-XL of Coulter company flow cytometer to detect the quantity of T lymphocyte subsets.
Table 1 medicine suffers from the impact of the pig immunologic function of pica
As can be seen from Table 1, the pig of drug treating group is compared with matched group, and the IL-2 in serum, gamma interferon, lymphocyte positive rate, CD4, CD4/CD8 value all increase.As can be seen here, medicine of the present invention has improved CD4(T accessory cell in pig immunocyte) and CD4(T accessory cell) with CD8(T suppress cell) ratio, increase the composition such as complement, IL-2, gamma interferon of serum, improve to a certain extent innate immune activity in pig body, strengthen the immunity of pig body.
The foregoing is only preferred embodiment of the present invention, in order to limit the present invention, within the spirit and principles in the present invention not all, any amendment of doing, be equal to replacement, improvement etc., within all should being included in protection scope of the present invention.
Claims (9)
1. one kind is used for the treatment of the Chinese medicine additive of pig pica, it is characterized in that, described Chinese medicine additive comprises following raw medicinal material: comb leaf Artemisia, Radix Malvae sylvestris, Herba boeae clarkeanae, Rhizoma Atractylodis, Folium Cremastrae appendiculatae, Concha Ostreae, Herba Violae philippicae, Os Draconis, Semen Arecae, Herba Epimedii, Cortex Acanthopancis, Poria, the Radix Paeoniae Alba, Radix Et Rhizoma Rhei, Pericarpium Citri Reticulatae, Largeleaf Gymnema, Bulbus Allii, Sputum Anseris domestica, Radix Angelicae Sinensis, Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, Fructus Aurantii, Cortex Magnoliae Officinalis, Fructus Forsythiae, Fructus Gardeniae, crab Qi, Massa Medicata Fermentata, Colysis bonii Ching., Fructus Hordei Germinatus, Herba Phlomidis Tuberosae, Herba cirsii esculenti, Peng Lai Pueraria lobota, Pueraria lobota Bud, Herba Cayatiae Japonicae and Drymotaenium miyoshianum (Mak.) Mak..
2. the Chinese medicine additive for the treatment of pig pica according to claim 1, is characterized in that, in described Chinese medicine additive, the parts by weight of each raw medicinal material are: comb leaf Artemisia 15-35 weight portion, Radix Malvae sylvestris 10-30 weight portion, Herba boeae clarkeanae 10-25 weight portion, Rhizoma Atractylodis 15-35 weight portion, Folium Cremastrae appendiculatae 10-35 weight portion, Concha Ostreae 10-30 weight portion, Herba Violae philippicae 15-35 weight portion, Os Draconis 10-30 weight portion, Semen Arecae 15-35 weight portion, Herba Epimedii 15-35 weight portion, Cortex Acanthopancis 10-30 weight portion, Poria 15-35 weight portion, Radix Paeoniae Alba 10-30 weight portion, Radix Et Rhizoma Rhei 15-35 weight portion, Pericarpium Citri Reticulatae 10-30 weight portion, Largeleaf Gymnema 10-30 weight portion, Bulbus Allii 15-35 weight portion, Sputum Anseris domestica 10-30 weight portion, Radix Angelicae Sinensis 15-35 weight portion, Radix Codonopsis 10-30 weight portion, Rhizoma Atractylodis Macrocephalae 15-35 weight portion, Fructus Aurantii 10-30 weight portion, Cortex Magnoliae Officinalis 10-30 weight portion, Fructus Forsythiae 15-30 weight portion, Fructus Gardeniae 10-30 weight portion, crab Qi 15-35 weight portion, Massa Medicata Fermentata 10-30 weight portion, Colysis bonii Ching. 15-35 weight portion, Fructus Hordei Germinatus 10-30 weight portion, Herba Phlomidis Tuberosae 15-35 weight portion, Herba cirsii esculenti 10-30 weight portion, Peng Lai Pueraria lobota 15-35 weight portion, Pueraria lobota Bud 10-30 weight portion, Herba Cayatiae Japonicae 15-35 weight portion and Drymotaenium miyoshianum (Mak.) Mak. 10-30 weight portion.
3. the Chinese medicine additive for the treatment of pig pica according to claim 1 and 2, is characterized in that, in described Chinese medicine additive, the parts by weight of each raw medicinal material are: comb leaf Artemisia 15-25 weight portion, Radix Malvae sylvestris 15-30 weight portion, Herba boeae clarkeanae 15-25 weight portion, Rhizoma Atractylodis 15-30 weight portion, Folium Cremastrae appendiculatae 15-35 weight portion, Concha Ostreae 15-30 weight portion, Herba Violae philippicae 15-30 weight portion, Os Draconis 15-30 weight portion, Semen Arecae 15-30 weight portion, Herba Epimedii 15-30 weight portion, Cortex Acanthopancis 15-30 weight portion, Poria 15-30 weight portion, Radix Paeoniae Alba 15-30 weight portion, Radix Et Rhizoma Rhei 15-30 weight portion, Pericarpium Citri Reticulatae 15-30 weight portion, Largeleaf Gymnema 15-30 weight portion, Bulbus Allii 15-30 weight portion, Sputum Anseris domestica 15-30 weight portion, Radix Angelicae Sinensis 15-30 weight portion, Radix Codonopsis 15-30 weight portion, Rhizoma Atractylodis Macrocephalae 15-30 weight portion, Fructus Aurantii 15-30 weight portion, Cortex Magnoliae Officinalis 15-25 weight portion, Fructus Forsythiae 15-25 weight portion, Fructus Gardeniae 15-30 weight portion, crab Qi 15-30 weight portion, Massa Medicata Fermentata 15-30 weight portion, Colysis bonii Ching. 15-30 weight portion, Fructus Hordei Germinatus 15-30 weight portion, Herba Phlomidis Tuberosae 15-30 weight portion, Herba cirsii esculenti 10-25 weight portion, Peng Lai Pueraria lobota 15-30 weight portion, Pueraria lobota Bud 15-30 weight portion, Herba Cayatiae Japonicae 15-30 weight portion and Drymotaenium miyoshianum (Mak.) Mak. 15-30 weight portion.
4. according to the Chinese medicine additive of the treatment pig pica described in claim 1-3 any one, it is characterized in that, in described Chinese medicine additive, the parts by weight of each raw medicinal material are: comb leaf Artemisia 18 weight portions, Radix Malvae sylvestris 17 weight portions, Herba boeae clarkeanae 25 weight portions, Rhizoma Atractylodis 25 weight portions, Folium Cremastrae appendiculatae 30 weight portions, Concha Ostreae 18 weight portions, Herba Violae philippicae 22 weight portions, Os Draconis 25 weight portions, Semen Arecae 20 weight portions, Herba Epimedii 28 weight portions, Cortex Acanthopancis 18 weight portions, Poria 17 weight portions, the Radix Paeoniae Alba 22 weight portions, Radix Et Rhizoma Rhei 25 weight portions, Pericarpium Citri Reticulatae 22 weight portions, Largeleaf Gymnema 17 weight portions, Bulbus Allii 20 weight portions, Sputum Anseris domestica 25 weight portions, Radix Angelicae Sinensis 18 weight portions, Radix Codonopsis 25 weight portions, the Rhizoma Atractylodis Macrocephalae 19 weight portions, Fructus Aurantii 25 weight portions, Cortex Magnoliae Officinalis 17 weight portions, Fructus Forsythiae 22 weight portions, Fructus Gardeniae 28 weight portions, crab Qi 18 weight portions, Massa Medicata Fermentata 22 weight portions, Colysis bonii Ching. 25 weight portions, Fructus Hordei Germinatus 18 weight portions, Herba Phlomidis Tuberosae 17 weight portions, Herba cirsii esculenti 20 weight portions, Peng Lai Pueraria lobota 22 weight portions, Pueraria lobota Bud 25 weight portions, Herba Cayatiae Japonicae 28 weight portions and Drymotaenium miyoshianum (Mak.) Mak. 19 weight portions.
5. according to the Chinese medicine additive of the treatment pig pica described in claim 1-4 any one, it is characterized in that, described Chinese medicine additive Raw medical material also comprises: Herba Zanthoxyli Myriacanthi, Carnis cauda Anseris domestica, Rui Liancao, Herba Scorzonerae Divaricatae and Rhizoma Smilacis.
6. according to the Chinese medicine additive of the treatment pig pica described in claim 1-5 any one, it is characterized in that, in described Chinese medicine additive, the parts by weight of each raw medicinal material are: comb leaf Artemisia 15-35 weight portion, Radix Malvae sylvestris 10-30 weight portion, Herba boeae clarkeanae 10-25 weight portion, Rhizoma Atractylodis 15-35 weight portion, Folium Cremastrae appendiculatae 10-35 weight portion, Concha Ostreae 10-30 weight portion, Herba Violae philippicae 15-35 weight portion, Os Draconis 10-30 weight portion, Semen Arecae 15-35 weight portion, Herba Epimedii 15-35 weight portion, Cortex Acanthopancis 10-30 weight portion, Poria 15-35 weight portion, Radix Paeoniae Alba 10-30 weight portion, Radix Et Rhizoma Rhei 15-35 weight portion, Pericarpium Citri Reticulatae 10-30 weight portion, Largeleaf Gymnema 10-30 weight portion, Bulbus Allii 15-35 weight portion, Sputum Anseris domestica 10-30 weight portion, Radix Angelicae Sinensis 15-35 weight portion, Radix Codonopsis 10-30 weight portion, Rhizoma Atractylodis Macrocephalae 15-35 weight portion, Fructus Aurantii 10-30 weight portion, Cortex Magnoliae Officinalis 10-30 weight portion, Fructus Forsythiae 15-30 weight portion, Fructus Gardeniae 10-30 weight portion, crab Qi 15-35 weight portion, Massa Medicata Fermentata 10-30 weight portion, Colysis bonii Ching. 15-35 weight portion, Fructus Hordei Germinatus 10-30 weight portion, Herba Phlomidis Tuberosae 15-35 weight portion, Herba cirsii esculenti 10-30 weight portion, Peng Lai Pueraria lobota 15-35 weight portion, Pueraria lobota Bud 10-30 weight portion, Herba Cayatiae Japonicae 15-35 weight portion, Drymotaenium miyoshianum (Mak.) Mak. 10-30 weight portion, Herba Zanthoxyli Myriacanthi 15-35 weight portion, Carnis cauda Anseris domestica 10-25 weight portion, the careless 10-20 weight portion of auspicious company, Herba Scorzonerae Divaricatae 15-35 weight portion and Rhizoma Smilacis 10-30 weight portion.
7. according to the Chinese medicine additive of the treatment pig pica described in claim 1-6 any one, it is characterized in that, in described Chinese medicine additive, the parts by weight of each raw medicinal material are: comb leaf Artemisia 25 weight portions, Radix Malvae sylvestris 22 weight portions, Herba boeae clarkeanae 18 weight portions, Rhizoma Atractylodis 25 weight portions, Folium Cremastrae appendiculatae 17 weight portions, Concha Ostreae 28 weight portions, Herba Violae philippicae 17 weight portions, Os Draconis 22 weight portions, Semen Arecae 20 weight portions, Herba Epimedii 25 weight portions, Cortex Acanthopancis 28 weight portions, Poria 22 weight portions, the Radix Paeoniae Alba 19 weight portions, Radix Et Rhizoma Rhei 18 weight portions, Pericarpium Citri Reticulatae 20 weight portions, Largeleaf Gymnema 27 weight portions, Bulbus Allii 19 weight portions, Sputum Anseris domestica 28 weight portions, Radix Angelicae Sinensis 18 weight portions, Radix Codonopsis 25 weight portions, the Rhizoma Atractylodis Macrocephalae 28 weight portions, Fructus Aurantii 25 weight portions, Cortex Magnoliae Officinalis 18 weight portions, Fructus Forsythiae 20 weight portions, Fructus Gardeniae 22 weight portions, crab Qi 25 weight portions, Massa Medicata Fermentata 28 weight portions, Colysis bonii Ching. 18 weight portions, Fructus Hordei Germinatus 28 weight portions, Herba Phlomidis Tuberosae 17 weight portions, Herba cirsii esculenti 25 weight portions, Peng Lai Pueraria lobota 27 weight portions, Pueraria lobota Bud 25 weight portions, Herba Cayatiae Japonicae 18 weight portions, Drymotaenium miyoshianum (Mak.) Mak. 27 weight portions, Herba Zanthoxyli Myriacanthi 20 weight portions, Carnis cauda Anseris domestica 22 weight portions, careless 20 weight portions of auspicious company, Herba Scorzonerae Divaricatae 30 weight portions and Rhizoma Smilacis 28 weight portions.
8. according to the Chinese medicine additive of the treatment pig pica described in claim 1-7 any one, it is characterized in that, in described Chinese medicine additive, the parts by weight of each raw medicinal material are: comb leaf Artemisia 15 weight portions, Radix Malvae sylvestris 30 weight portions, Herba boeae clarkeanae 25 weight portions, Rhizoma Atractylodis 30 weight portions, Folium Cremastrae appendiculatae 35 weight portions, Concha Ostreae 30 weight portions, Herba Violae philippicae 28 weight portions, Os Draconis 25 weight portions, Semen Arecae 28 weight portions, Herba Epimedii 30 weight portions, Cortex Acanthopancis 20 weight portions, Poria 30 weight portions, the Radix Paeoniae Alba 28 weight portions, Radix Et Rhizoma Rhei 28 weight portions, Pericarpium Citri Reticulatae 22 weight portions, Largeleaf Gymnema 18 weight portions, Bulbus Allii 22 weight portions, Sputum Anseris domestica 25 weight portions, Radix Angelicae Sinensis 18 weight portions, Radix Codonopsis 25 weight portions, the Rhizoma Atractylodis Macrocephalae 28 weight portions, Fructus Aurantii 27 weight portions, Cortex Magnoliae Officinalis 25 weight portions, Fructus Forsythiae 22 weight portions, Fructus Gardeniae 30 weight portions, crab Qi 22 weight portions, Massa Medicata Fermentata 19 weight portions, Colysis bonii Ching. 25 weight portions, Fructus Hordei Germinatus 18 weight portions, Herba Phlomidis Tuberosae 28 weight portions, Herba cirsii esculenti 25 weight portions, Peng Lai Pueraria lobota 19 weight portions, Pueraria lobota Bud 27 weight portions, Herba Cayatiae Japonicae 17 weight portions, Drymotaenium miyoshianum (Mak.) Mak. 22 weight portions, Herba Zanthoxyli Myriacanthi 25 weight portions, Carnis cauda Anseris domestica 20 weight portions, careless 17 weight portions of auspicious company, Herba Scorzonerae Divaricatae 28 weight portions and Rhizoma Smilacis 22 weight portions.
9. according to the preparation method of the Chinese medicine additive of the treatment pig pica described in claim 1-8 any one, it is characterized in that, it is characterized in that, described preparation method comprises the following steps:
Step 1, take all raw medicinal materials according to parts by weight, and be ground into 40 order-60 object powder;
Step 2, above-mentioned gained powder is carried out to charcoal fry 1.0-2.5 hour, adding subsequently with respect to mixture quality 2-4 determining alcohol is doubly 75%-85% alcoholic solution, and heating and refluxing extraction 4.5-7 hour obtains the first extracting solution, filters, and obtains the first filtrate; It is 65%-90% alcoholic solution that filtering residue adds with respect to its quality 2-5 determining alcohol doubly again, heating and refluxing extraction 1.5-3 hour, obtains the second extracting solution, filters, obtain the second filtrate, the first filtrate and the second filtrate are merged, be uniformly mixed, concentrating under reduced pressure, remove ethanol, obtain dry mastic, adopt subsequently pulverizer that dry gained mastic is pulverized, grinding particle size 270 order-400 orders, obtain pulverous described Chinese medicine additive.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN113040284A (en) * | 2021-04-22 | 2021-06-29 | 唐满红 | Feed additive for preventing sow feeding nodules and preparation method thereof |
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Application publication date: 20140730 |