CN103933294B - A kind of plant extract compositions for sexual dysfunction - Google Patents
A kind of plant extract compositions for sexual dysfunction Download PDFInfo
- Publication number
- CN103933294B CN103933294B CN201410117322.4A CN201410117322A CN103933294B CN 103933294 B CN103933294 B CN 103933294B CN 201410117322 A CN201410117322 A CN 201410117322A CN 103933294 B CN103933294 B CN 103933294B
- Authority
- CN
- China
- Prior art keywords
- parts
- radix
- fructus
- semen
- herba
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to treat a kind of plant extract compositions for sexual dysfunction, following proportioning raw materials obtain: Flos abelmoschi manihot, Fructus Lycii, Rhizoma Cibotii, Semen Ziziphi Spinosae, Radix Rehmanniae Preparata, Poria, Herba Taraxaci, Herba Epimedii, Radix Polygalae, Semen Cuscutae, Herba Cistanches, Fructus Schisandrae Chinensis, Rhizoma Chuanxiong, Herba Houttuyniae, Fructus Mori, Flos Campsis, Semen Euryales, Fructus Rubi, Rhizoma Dioscoreae, Semen Persicae, Flos Osmanthi Fragrantis, the Radix Paeoniae Alba, Radix Et Caulis Acanthopanacis Senticosi, Radix Morindae Officinalis, Radix Glycyrrhizae, Fructus Corni, Cortex Phellodendri.All medicines share, and bring out the best in each other, obvious to impotence treatment effect, stable, strengthen male's sexual, have a extensive future.
Description
Technical field
The invention belongs to health product technology field, concrete, relate to a kind of plant extract compositions for sexual dysfunction
Background technology
Sexual dysfunction refer to male in five stages of the sexual activitys such as libido, erection, sexual intercourse, orgasm, ejaculation, wherein certain stage or several stage or all stage occur abnormal and affect sexual activity and be normally carried out.The most common male sexual disorder is erection and ejaculates abnormal.Male's sexual is a complicated physiological process, relates to each side, such as nervous and mental factors, endocrine function, sexual organ etc., and the most corticocerebral property trained reflex plays particularly important mastery reaction.As can be seen here, the reason causing male sexual disorder is also many, can be divided into functionality dysfunction and the big class of organic sexual dysfunction two generally, and the former accounts for the overwhelming majority of sexual dysfunction, and the latter is the most rare.Erection disturbance (ED) is also known as sexual impotence.The most modal male sexual disorder, its not only sickness rate high, have a strong impact on men's health, and the trend of oriented rejuvenation development.Particularly in the modern life, the rhythm of life of people is fast, and stress is big, eating and drinking too much at one meal, and monophagia excessive drinking etc. the most easily causes male sexual disorder, sexual impotence symptom occurs.According to statistics 40～man had in 70 years old 52% to suffer from ED in various degree.
Existing therapeutic modality can be divided into Noninvasive and invasive to treat two classes, and noninvasive laser therapy means that psychotherapy, Drug therapy and negative pressure of vacuum are erected and treats.Invasive treatment includes that the injection of urethral administration, spongy body active medicine, penile prosthesis are implanted and the operative treatment of vascular sexual impotence.Invasive treatment is with certain traumatic, and complication is many, and patient is not easily accepted by；Drug therapy is presently mainly based on Western medicine, it mostly is phosphodiesterase-5 (PDE-5) inhibitor: such as sldenafil (viagra, Pfizer), Vardenafil (Ai Lida, Beyer Co., Ltd) although etc. curative effect certainly, but it is expensive, general patient is difficult to bear, and can cause and make us unacceptable side effect such as headache, hypotension, cardiovascular adverse effects etc..
The traditional Chinese medical science thinks that the erection of penis is by the result of the mutually coordinated effect of a series of zang-fu differentiation and qi-blood-body fluid, therefore the morbidity of sun expectorant, often with emotional stimulation, impairment caused by overstrain excessively, six climate exopathogens invasion and attack, improper diet, tumbling down damage, prolonged illness are tired out, to examine factors such as composing deficiency, year high asthenia relevant, these causes of disease can individually be caused a disease, but it is that the double folder of two or more cause of disease causes a disease in the case of more, complex syndrome is caused to change, because inside and outside various pathological factors cause the functional activity imbalance or impaired of internal organs and meridians, erection disturbance all can be produced.Chinese medical discrimination sexual impotence is divided into: 1. vital essence virtual loss, decline of the fire from the gate of life；2. QI and blood deficiency, penis loses supports；3. fear is impairment of the kidney, and sun road is depressed；4. stagnation of liver-QI is not relaxed, depression of liver-QI sexual impotence；5. damp invasion of lower energizer etc. pattern of syndrome, treats the most flexible.The traditional Chinese medical science thinks that stagnation of liver-QI is not relaxed, liver governing tendons, and external genitals is the remittance of penis.If feelings will is unsuccessful, anxiety and rage, the liver failing to maintain the normal flow of QI bar reaches, it is impossible to dredging vim and vigour and fluent external genitalia, then penis is gathered incapability, and this sexual impotence includes the category of modern medicine psychic impotence.Easily there is this pattern of syndrome sexual impotence due to social environmental factor in male, and to determined curative effect, treatment easy to use, health medicine has exact demand.Prior art prescriptions of Chinese medicine lacks dialectical, and treatment cycle is long, and property is not strong to the ill, and curative effect is inconspicuous, the most also can bring side effect to patient, increase patient suffering, finds effective, safe drugs, it has also become the problem generally needing to solve from natural drug.
Summary of the invention
The present invention is with reference to motherland's medical science understanding pathogenetic to sexual impotence and the invaluable experience for the treatment of, refering to existing reasonable formula, determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, according to Chinese Pharmacopoeia and pharmacology compatibility, pushing away Chen Zhixin gain, determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs is always the core theory of Chinese medicine disease, how to take into account secondary pathogenesis for main pathogenesis medication simultaneously, take into account the treatment of general character and individual character, thus at utmost embody intension and the extension of Chinese traditional treatment disease, be a realistic problem of Chinese patent medicine compatibility.Theoretical by Chinese medical discrimination, causing the Etiological pathogenesis of sexual impotence is that deficiency of kidney-YIN, damage of essence harmony be stagnant, depressed emotion, caused by energy stagnation and blood stasis.Treatment should reach the purpose for the treatment of both the principal and the secondary aspects of a disease at the same time with supplementing the kidney to control the nocturnal, nourishing YIN and invigorating YANG, QI regulating by alleviation of mental depression, activating blood circulation to dissipate blood stasis.Inventor is by the research to Chinese medicine, and combine dialectical demonstration, in many ways the length of many families is collected, seek therapeutic regimen, from motherland's medical treasure-house, filter out nourishing YIN and invigorating YANG, QI regulating by alleviation of mental depression, the natural component of activating blood circulation to dissipate blood stasis, by theory of Chinese medical science prescription, skim the cream off milk, the plant extract compositions for sexual dysfunction of the present invention meticulously it is configured in conjunction with Traditional Chinese Medicine technology, relative to Western medicine, obvious to impotence treatment effect, stable, strengthen male's sexual, and commonly used energy health invigorating, resisting fatigue, cardio-cerebral diseases will not be induced, useful men's health.
For realizing the object of the invention, the technical solution used in the present invention is as follows:
A kind of Chinese medicine composition for male sexual disorder, it is characterised in that be prepared by the raw material of following weight proportioning:
Flos abelmoschi manihot 30 parts, Fructus Lycii 25 parts, Rhizoma Cibotii 25 parts, Semen Ziziphi Spinosae 20 parts, Radix Rehmanniae Preparata 20 parts,
20 parts of Poria, Herba Taraxaci 20 parts, Herba Epimedii 18 parts, Radix Polygalae 18 parts, Semen Cuscutae 18 parts,
Herba Cistanches 15 parts, Fructus Schisandrae Chinensis 15 parts, Rhizoma Chuanxiong 15 parts, Herba Houttuyniae 15 parts, 15 parts of Fructus Mori,
Flos Campsis 13 parts, Semen Euryales 12 parts, Fructus Rubi 12 parts, Rhizoma Dioscoreae 10 parts, 10 parts of Semen Persicae,
Flos Osmanthi Fragrantis 10 parts, the Radix Paeoniae Alba 10 parts, Radix Et Caulis Acanthopanacis Senticosi 10 parts, Radix Morindae Officinalis 8 parts, 8 parts of Radix Glycyrrhizae,
Fructus Corni 8 parts, Cortex Phellodendri 5 parts.
The pharmaceutical composition its preparation method of the present invention is: the crude drug (such as proportioning unit: gram) taking above-mentioned parts by weight prepares capsule, and concrete operations are:
1) each crude drug is weighed, standby；
2) take Flos abelmoschi manihot 30 parts, Fructus Lycii 25 parts, Rhizoma Cibotii 25 parts, Radix Polygalae 18 parts, Semen Cuscutae 18 parts, Herba Cistanches 15 parts, Fructus Schisandrae Chinensis 15 parts, Rhizoma Chuanxiong 15 parts, Radix Et Caulis Acanthopanacis Senticosi 10 parts, Radix Morindae Officinalis 8 parts, 8 parts of Radix Glycyrrhizae, Fructus Corni 8 parts add the water intense fire of 5 times of weight and boil, then slow fire boiling 1 hour, is collected by filtration filtrate and filtering residue；Adding water in filtering residue, not have filtering residue to be as the criterion, intense fire boils, and then slow fire boiling 30 minutes, are collected by filtration filtrate；Merge above-mentioned twice filtrate, after cooling, be condensed into the extractum that density is 1.2g/ml；After 80 DEG C dry, it is ground into powder, is complex A；
3) take Semen Ziziphi Spinosae 20 parts, Radix Rehmanniae Preparata 20 parts, 20 parts of Poria, Herba Taraxaci 20 parts, Herba Epimedii, Herba Houttuyniae 15 parts, 15 parts of Fructus Mori, Flos Campsis 13 parts, Semen Euryales 12 parts, Fructus Rubi 12 parts, Rhizoma Dioscoreae 10 parts, 10 parts of Semen Persicae, Flos Osmanthi Fragrantis 10 parts, the Radix Paeoniae Alba 10 parts, Cortex Phellodendri 5 parts add 70% soak with ethanol 0.5-1.5 hour, not have crude drug to be as the criterion, extract twice, 1-2 hour every time, united extraction liquid, filters, is condensed into the extractum that relative density is 1.2, crushed after being dried, obtains complex B
5) by complex A, complex B mixing and stirring, sterilization prepares capsule product, oral each 1g, twice on the one.
The component of medicine of the present invention all uses natural raw material of Chinese medicine, and it prepares simplicity, and medicine source is extensive, with low cost, it follows the prescriptions principle of the traditional Chinese medical science, and all medicines share, and bring out the best in each other, and monarch respectively executes its effect, expansion blood vessel, increases blood flow, blood circulation promoting, improves reproductive system blood supply insufficiency.By regulation central nervous system to gonad axis effect, excited hypophysis, increasing adrenocortical hormone sample effect, the kidney warming controlling nocturnal emission with astringent drugs, improve penile erectile function, prolonged erection time, therapeutic effect is obvious, stable；The inventive method does not bias toward kidney-replenishing, kidney yin, or it is supporing yang to mend fire, the most commonly used will not induce cardio-cerebral diseases, infringement health yet, verifies by clinic application, and it is evident in efficacy reliably, and mild in medicine property has a extensive future.
Detailed description of the invention
Embodiment 1
A kind of Chinese medicine composition for male sexual disorder, it is characterised in that be prepared by the raw material of following weight proportioning:
Flos abelmoschi manihot 30 parts, Fructus Lycii 25 parts, Rhizoma Cibotii 25 parts, Semen Ziziphi Spinosae 20 parts, Radix Rehmanniae Preparata 20 parts,
20 parts of Poria, Herba Taraxaci 20 parts, Herba Epimedii 18 parts, Radix Polygalae 18 parts, Semen Cuscutae 18 parts,
Herba Cistanches 15 parts, Fructus Schisandrae Chinensis 15 parts, Rhizoma Chuanxiong 15 parts, Herba Houttuyniae 15 parts, 15 parts of Fructus Mori,
Flos Campsis 13 parts, Semen Euryales 12 parts, Fructus Rubi 12 parts, Rhizoma Dioscoreae 10 parts, 10 parts of Semen Persicae,
Flos Osmanthi Fragrantis 10 parts, the Radix Paeoniae Alba 10 parts, Radix Et Caulis Acanthopanacis Senticosi 10 parts, Radix Morindae Officinalis 8 parts, 8 parts of Radix Glycyrrhizae,
Fructus Corni 8 parts, Cortex Phellodendri 5 parts.
The pharmaceutical composition its preparation method of the present invention is: the crude drug (such as proportioning unit: gram) taking above-mentioned parts by weight prepares capsule, and concrete operations are:
1) each crude drug is weighed, standby；
2) take Flos abelmoschi manihot 30 parts, Fructus Lycii 25 parts, Rhizoma Cibotii 25 parts, Radix Polygalae 18 parts, Semen Cuscutae 18 parts, Herba Cistanches 15 parts, Fructus Schisandrae Chinensis 15 parts, Rhizoma Chuanxiong 15 parts, Radix Et Caulis Acanthopanacis Senticosi 10 parts, Radix Morindae Officinalis 8 parts, 8 parts of Radix Glycyrrhizae, Fructus Corni 8 parts add the water intense fire of 5 times of weight and boil, then slow fire boiling 1 hour, is collected by filtration filtrate and filtering residue；Adding water in filtering residue, not have filtering residue to be as the criterion, intense fire boils, and then slow fire boiling 30 minutes, are collected by filtration filtrate；Merge above-mentioned twice filtrate, after cooling, be condensed into the extractum that density is 1.2g/ml；After 80 DEG C dry, it is ground into powder, is complex A；
3) take Semen Ziziphi Spinosae 20 parts, Radix Rehmanniae Preparata 20 parts, 20 parts of Poria, Herba Taraxaci 20 parts, Herba Epimedii, Herba Houttuyniae 15 parts, 15 parts of Fructus Mori, Flos Campsis 13 parts, Semen Euryales 12 parts, Fructus Rubi 12 parts, Rhizoma Dioscoreae 10 parts, 10 parts of Semen Persicae, Flos Osmanthi Fragrantis 10 parts, the Radix Paeoniae Alba 10 parts, Cortex Phellodendri 5 parts add 70% soak with ethanol 0.5-1.5 hour, extract twice, 1-2 hour every time, united extraction liquid, filter, it is condensed into the extractum that density is 1.2g/ml, crushed after being dried, obtains complex B
5) by complex A, complex B mixing and stirring, sterilization prepares capsule product, oral each 1g, twice on the one.
Embodiment 2
One, toxicity test
This experiment uses healthy SD rat, the drug dose gradient of oral administration embodiment 1 preparation is 10mg/kg and 20mg/kg, successive administration 30 days, during it be observed that rat administration and after drug withdrawal, within 1 week, growth of animal state, movable diet, hematology, blood biochemical analysis, organs and tissues structure and routine urinalysis etc. all have no significant effect, and show that clinical drug safety is reliable.
Two, mice mating test
Mice mating is tested.Take kunming mice 60, blank group 30, experimental group 30, often organize male 5, female Mus 25.Every 5 mouse cages of component are raised.Every male Mus is raised with cage with 5 female Mus.Experimental technique: blank group (distilled water), medicine group of the present invention (10mg/kg).Often group gastric infusion hero Mus, is administered once respectively in morning every day, afternoon, continuous 10 days.Every morning checks that female Mus has depletion of YIN bolt to occur.As shown in the table:
Mice mating test table
| Group | Female Mus number of cases | Find cloudy bolt number of cases (10d) | Cloudy bolt occurrence rate |
| Blank group | 25 | 9 | 36% |
| Medicine group of the present invention | 25 | 22 | 88% |
As can be seen from the above table, medicine group of the present invention can be obviously promoted male mice mating.
Three, mice plasma testosterone experiment:
Take ICR system cleaning grade Kunming male mice 40, it is randomly divided into blank group (distilled water), medicine group of the present invention, often group 20, often organize gastric infusion, the morning respectively every day, afternoon are administered once, and after continuous 10 days, mice is plucked eyeball and takes blood, detection blood plasma testosterone content, as shown in the table:
Mice plasma testosterone is tested:
| Group | Male Mus number of cases | Testosterone |
| Blank group | 20 | 6.37±1.41 |
| Medicine group of the present invention | 20 | 31.23±1.35 |
As can be seen from the above table, the embodiment of the present invention 1 medicine can substantially increase the content of male mice plasma testosterone, promotes male mice mating, improves male mice sexual function.
Embodiment 3
Clinical data
106 example sexual impotence patients of diagnosis will be met, be randomly divided into treatment group and each 53 examples of matched group.The aspects such as two groups of patient ages, the course of disease, erection function integration and state of an illness weight, the most all without significant difference, have comparability.
Diagnostic criteria diagnoses principle with reference to international dysfunction, i.e. man is under sexual stimulus, lasting or repeatedly can not reach or maintain enough hardness erection to complete to be satisfied with sexual intercourse, and the course of disease is more than 3 months, international index of erectile function questionnaire (IIEF-5)≤21 point.
Exclusion standard (1) complication with diabetes person；(2) the disease patients such as the serious heart, liver, kidney, hemopoietic system it are associated with；(3) prostate substantially increases survivor or prostatitis specific antigen (PSA) ＞ 4ug/ml person；(4) psychotic；(5) other related drugs person was taken in the recent period；(6) the most incomplete by regulation medication or data, it is impossible to adhere to normal subjects.
Therapeutic Method:
Treatment group takes the plant extract compositions of embodiment 1 preparation, oral each 1g, twice on the one.
Matched group takes LIUWEI DIHUANG WAN, 8 tablets/time, 3 times on the 1st；
All treat 8 weeks for two groups.Before treatment, treatment 4 weeks, treat 8 weeks and observe erection function world questionnaire (IIEF-5) integration respectively and change, including erection confidence, be successively inserted into number of times, erection hardness, maintenance erectile ability and 5 problems of coitus satisfaction degree.
Criterion of therapeutical effect clinic control: after treatment, sexual intercourse chance reaches more than 75% success, or erection function integration >=21 point；Effective: after treatment, sexual intercourse chance reaches more than 50% success, or erection function integration increases 7-14 earlier above and divides；Effective: after treatment, sexual intercourse chance reaches more than 25% success, or erection function integration increases≤7 points earlier above；Invalid: after treatment, sexual intercourse chance success rate is unchanged, or erection function integration is without increasing.
Therapeutic outcome
Two groups all treat 8 weeks after add up curative effect.Two groups of comparitive study are shown in Table 1.
Table 1: efficacy result
| Group | Number of cases | Effective | Effectively | Invalid | Total effective rate |
| Treatment group | 53 | 30 | 20 | 3 | 94.3% |
| Matched group | 53 | 15 | 23 | 15 | 71.7% |
Treatment group relatively matched group significant difference.
Embodiment 4
Model case
1 Wang, 32 years old, described in patient, sun device was not lifted, have within 2 years, have a surplus, and with urine not to the utmost, lumbago is felt, once takes multiple kidney-reinforcing drug, the most to no effect, give embodiment 1 preparation after the plant extract compositions 4 weeks of sexual dysfunction, sexual function has significantly improvement, but recurs again after drug withdrawal；After serveing on 2 months, all diseases are removed entirely, follow up a case by regular visits to, and do not recur after 2 years；
2 military certain, 41 years old, disease 3 years, sun device lift and the hardest, face room premature ejaculation, waist knee joint epidemic disease is soft, deficient pulse is unable, body of the tongue is yellowish, give embodiment 1 preparation after the plant extract compositions one week of sexual dysfunction, symptom substantially alleviates, take medicine continuously five weeks, sun device lift and hard, within after drug withdrawal 1 year, follow up a case by regular visits to, do not recur.
3 Lee, 27 years old, because sun device is not lifted after marriage, occur that libido is cold, and erection is the hardest.Causing conjugal relation not conform to, patient seeks medical advice many places, has no positive effect, by the plant extract compositions three weeks for sexual dysfunction taking embodiment 1 preparation, sun device is lifted, and the bimester of serveing on, its disease is removed, sexual function recovers normal, and erection is strong, during the same branch of a family sustainable 10～15 minutes.
Listed above is only the optimal specific embodiment of the present invention.It is clear that the invention is not restricted to above example, it is also possible to there are many deformation.All deformation that those of ordinary skill in the art can directly derive from present disclosure or associate, are all considered as protection scope of the present invention.
Claims (1)
1. the plant extract compositions being used for treating male sexual disorder, it is characterised in that by the raw material preparation of following weight parts
:
Flos abelmoschi manihot 30 parts, Fructus Lycii 25 parts, Rhizoma Cibotii 25 parts, Semen Ziziphi Spinosae 20 parts, Radix Rehmanniae Preparata 20 parts,
20 parts of Poria, Herba Taraxaci 20 parts, Herba Epimedii 18 parts, Radix Polygalae 18 parts, Semen Cuscutae 18 parts,
Herba Cistanches 15 parts, Fructus Schisandrae Chinensis 15 parts, Rhizoma Chuanxiong 15 parts, Herba Houttuyniae 15 parts, 15 parts of Fructus Mori,
Flos Campsis 13 parts, Semen Euryales 12 parts, Fructus Rubi 12 parts, Rhizoma Dioscoreae 10 parts, 10 parts of Semen Persicae,
Flos Osmanthi Fragrantis 10 parts, the Radix Paeoniae Alba 10 parts, Radix Et Caulis Acanthopanacis Senticosi 10 parts, Radix Morindae Officinalis 8 parts, 8 parts of Radix Glycyrrhizae,
Fructus Corni 8 parts, Cortex Phellodendri 5 parts；
The preparation method of described plant extract compositions comprises the steps:
1) each crude drug is weighed according to weight portion, standby；
2) Flos abelmoschi manihot, Fructus Lycii, Rhizoma Cibotii, Radix Polygalae, Semen Cuscutae, Herba Cistanches, Fructus Schisandrae Chinensis, Rhizoma Chuanxiong, Radix Et Caulis Acanthopanacis Senticosi, Radix Morindae Officinalis, Radix Glycyrrhizae are taken
And Fructus Corni, adding the water of 5 times of weight, intense fire boils, then slow fire boiling 1 hour, and filtrate and filtering residue are collected by filtration；Past
Adding water in filtering residue, not have filtering residue to be as the criterion, intense fire boils, and then slow fire boiling 30 minutes, are collected by filtration filtrate；In merging
State twice filtrate, after cooling, be condensed into the extractum that density is 1.2g/ml；After 80 DEG C dry, it is ground into powder, is complex
A；
3) Semen Ziziphi Spinosae, Radix Rehmanniae Preparata, Poria, Herba Taraxaci, Herba Epimedii, Herba Houttuyniae, Fructus Mori, Flos Campsis, Semen Euryales, Fructus Rubi, mountain are taken
Medicine, Semen Persicae, Flos Osmanthi Fragrantis, the Radix Paeoniae Alba and Cortex Phellodendri, add 70% soak with ethanol 0.5-1.5 hour, extracts twice, each 1-2 hour,
United extraction liquid, filters, is condensed into the extractum that density is 1.2g/ml, crushed after being dried, obtains complex B；
4) by complex A and complex B mixing and stirring, sterilization and get final product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410117322.4A CN103933294B (en) | 2014-03-25 | 2014-03-25 | A kind of plant extract compositions for sexual dysfunction |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410117322.4A CN103933294B (en) | 2014-03-25 | 2014-03-25 | A kind of plant extract compositions for sexual dysfunction |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103933294A CN103933294A (en) | 2014-07-23 |
| CN103933294B true CN103933294B (en) | 2017-01-04 |
Family
ID=51181351
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410117322.4A Active CN103933294B (en) | 2014-03-25 | 2014-03-25 | A kind of plant extract compositions for sexual dysfunction |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103933294B (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104147235A (en) * | 2014-08-20 | 2014-11-19 | 熊菊莲 | Traditional Chinese medicine capsule for treating impotence and premature ejaculation |
| CN104352994A (en) * | 2014-11-28 | 2015-02-18 | 张海燕 | Pharmaceutical preparation for sexual dysfunction |
| CN104491677A (en) * | 2014-11-28 | 2015-04-08 | 张海燕 | Preparation method of medicament for treating sexual dysfunction |
| CN117653701B (en) * | 2023-12-25 | 2024-10-18 | 江西天元药业有限公司 | Composition for treating male sexual dysfunction |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103520618A (en) * | 2013-10-21 | 2014-01-22 | 赵吉利 | Preparation method of okra plant viagra |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7629384B2 (en) * | 1997-09-17 | 2009-12-08 | Strategic Science & Technologies, Llc | Topical delivery of L-arginine to cause beneficial effects |
-
2014
- 2014-03-25 CN CN201410117322.4A patent/CN103933294B/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103520618A (en) * | 2013-10-21 | 2014-01-22 | 赵吉利 | Preparation method of okra plant viagra |
Non-Patent Citations (2)
| Title |
|---|
| 中医治疗阳痿选方;刘国应;《开卷有益 求医问药》;19961231(第1期);第21-22页，尤其是第21页左栏第三段 * |
| 心因性阳痿从肝论治心得;李南安;《湖北省卫生职工医学院学报》;19951231(第2期);第56页左栏最后一段 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103933294A (en) | 2014-07-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103520618B (en) | A kind of pharmaceutical composition for the treatment of erection disturbance and preparation method thereof and pharmaceutical applications | |
| CN101810685B (en) | Chinese medicinal composition for treating gonitis and preparation method thereof | |
| CN103933294B (en) | A kind of plant extract compositions for sexual dysfunction | |
| CN101698020B (en) | Traditional Chinese medicine preparation for treating femoral head necrosis and preparation method thereof | |
| CN102895460B (en) | Traditional Chinese medicine composition for fracture and soft tissue injury | |
| CN104248722A (en) | Medicament for treating female hypersexuality | |
| CN104288624A (en) | Pharmaceutical composition and application thereof | |
| CN106236980A (en) | A kind of Chinese medicine extract treating impotence and preparation method thereof | |
| CN102114195A (en) | Anti-drug capsule prepared from pure traditional Chinese medicines | |
| CN102188586A (en) | Yang-tonifying and body-building capsule for improving kidney function and preparation method thereof | |
| CN104491677A (en) | Preparation method of medicament for treating sexual dysfunction | |
| CN104352994A (en) | Pharmaceutical preparation for sexual dysfunction | |
| CN103142897B (en) | Medicine used after esophageal achalasia operation | |
| CN101757396B (en) | Traditional Chinese medicine composition for treating deficiency of kidney qi and impotence and spermatorrhea and preparation method thereof | |
| CN103520684A (en) | Traditional Chinese medicine compound for reducing blood sugar | |
| CN100400086C (en) | Medicine for treating low function of ovary | |
| CN103495079B (en) | Chinese herbal compound composition with male infertility therapy effect and preparation method and application of Chinese herbal compound composition | |
| CN101301379B (en) | Chinese medicinal composition and preparation and use thereof | |
| CN102727730B (en) | Traditional Chinese medicinal compound preparation for treating male infertility and its preparation method | |
| CN103142898B (en) | Preparation method of medicine used after esophageal achalasia operation | |
| CN106267084A (en) | A kind of Chinese medicine composition treating impotence | |
| CN104758539A (en) | Traditional Chinese medicine composition for treating debilitation | |
| CN105362999A (en) | Traditional Chinese medicine preparation for preventing and treating infantile repeated cold and preparation method thereof | |
| CN104958504A (en) | Traditional Chinese medicine composition for preventing and treating sub-health and preparation method of traditional Chinese medicine composition | |
| CN102697833B (en) | Yang-tonifying and pregnancy-promoting health-care Chinese medicinal composition |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C41 | Transfer of patent application or patent right or utility model | ||
| CB03 | Change of inventor or designer information |
Inventor after: Zhang Li Inventor before: Shi Hong Inventor before: Cao Hongxing |
|
| COR | Change of bibliographic data | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20160920 Address after: 69 Feixian County people's Hospital, Feixian County health Road, Shandong, 273400, Linyi, China Applicant after: Zhang Li Address before: 20, Shuang Xing street, Xigang District, Liaoning, Dalian, 3-5 Applicant before: Jiang Li |
|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20170822 Address after: Haimen City Jiangsu city of Nantong province is more than 226100 Zhenan Bridge Village nine Group No. 101 Patentee after: Haimen Chuanghao Industrial Design Co.,Ltd. Address before: 69 Feixian County people's Hospital, Feixian County health Road, Shandong, 273400, Linyi, China Patentee before: Zhang Li |
|
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20231015 Address after: Room 1103, Unit 2, Building 7, Xiangyi Huafu, Huajian Road, Zhanggong District, Ganzhou, Jiangxi Province 341000 Patentee after: Zhao Xianliang Address before: 226100 No. 101, Nine Groups, Banqiao Village, Zhengyu Town, Haimen City, Nantong City, Jiangsu Province Patentee before: Haimen Chuanghao Industrial Design Co.,Ltd. |
|
| TR01 | Transfer of patent right |