CN103918899A - Application of astragalus polysaccharide - Google Patents

Abstract

The invention relates to the field of regulation and control on rumen of ruminants, and discloses application of a natural product preparation, namely, astragalus polysaccharide, to promotion of rumen fermentation. Astragalus polysaccharide is used for regulating and controlling microbial fermentation of rumen of ruminants. As discovered by a great deal of experimental research, astragalus polysaccharide can be used for well regulating and controlling microbial fermentation of rumen of ruminants in order to increase the feed utilization ratio and increase the yield of volatile acid as well as microbial activity. By means of scientific mixture of astragalus polysaccharide, the rumen function can be improved, and the health of ruminants can be promoted.

Description

A kind of application of astragalus polysaccharide

technical field

The invention relates to the field of rumen regulation, in particular to the use of a natural product preparation, astragalus polysaccharide, for promoting rumen fermentation.

Background technique

With the development of science and technology, animal husbandry is gradually developing in the direction of intensification, mechanization, science and standardization, but in this process, the breeding industry is always restricted by the spread of diseases. Although people try to reduce this impact by implementing various measures such as animal immunization and improving the living environment of animals, the effect is not ideal all the time. Many factors, such as immune failure, abuse of antibiotics, etc., can cause low immune function in animals. Adding immune enhancers is a very effective solution. It can not only improve the immunity of animals, promote the healthy growth of animals, but also avoid the side effects caused by the use of antibiotics.

A large number of microorganisms live in the rumen of dairy cows, and these microorganisms can not only degrade feed but also synthesize various nutrients. The rumen can be regarded as a fermenter for the reproduction of anaerobic microorganisms and plays an important role in the entire digestion process. Nutrients are degraded by microorganisms in the rumen into components such as volatile fatty acids, peptides and amino acids, and are used by microorganisms to synthesize bacterial proteins and B vitamins. The function of rumen microorganisms is closely related to the rumen environment. How to maintain a good and stable rumen environment, maintain the activity of microorganisms and the relative balance of bacterial strains is an important part of dairy cow feeding.

There is a close relationship between the digestion and metabolism of nutrients in dairy cows and their lactation performance. The use of rumen regulators to regulate the rumen environment of ruminants has been widely used in production to improve the utilization of dietary nutrients and production performance. At present, the rumen regulators commonly used in dairy production are mainly baking soda, magnesium oxide, yeast culture and Chinese herbal medicine. Among them, Chinese herbal medicine has the characteristics of the same origin, same body and same use as food, with less toxic and side effects, no drug resistance, and multiple functions, which are incomparable to modern chemical drugs, antibiotics and hormone drugs. However, there is no report on the regulation of the rumen environment by astragalus polysaccharides.

Contents of the invention

The object of the present invention is to provide a use of astragalus polysaccharide.

The specific plan is:

The invention relates to an application of astragalus polysaccharide, which is to use astragalus polysaccharide to regulate rumen microbial fermentation of ruminants.

Polysaccharides widely exist in animals, plants, and microorganisms (bacteria, fungi, etc.), and come from natural plant polysaccharides. They have the advantages of non-toxicity, no side effects, and no residues, so they have attracted widespread attention. Studies have shown that plant polysaccharides have various physiological activities such as anti-tumor, anti-virus, anti-infection, anti-aging, and improving immunity of the body, and are widely used in medical research and human health care. At present, plant polysaccharides have also begun to be applied to livestock and poultry production. Studies have shown that adding plant polysaccharides to feed can significantly improve the immune function of livestock and poultry, promote animal growth, and reduce animal mortality.

Astragalus is the dried root of the leguminous plant Astragalus mongolica or Astragalus membranaceus. Astragalus polysaccharide is one of the active ingredients extracted from the traditional Chinese medicine Astragalus. It is a macromolecular polysaccharide composed of glucose, galactose, and arabinose. Studies have confirmed that astragalus polysaccharides can improve animal production performance, enhance the body's immune function and disease resistance in animal production. For example, astragalus polysaccharides can interfere with, phagocytize, and combine with a variety of viruses to kill viruses, and are suitable for viral diseases such as infectious bursal disease, Marek's disease, infectious bronchitis, and avian myeloblastic leukemia prevention and treatment. However, the current research on APS is only in the field of monogastric animals, and there is no research on the effect of APS on rumen regulation in ruminants at home and abroad.

In the present invention, through a large number of experimental studies, it is found that the astragalus polysaccharide can well regulate the rumen microbial fermentation of ruminants, promote feed utilization, increase volatile acid production and microbial activity, and the like.

The specific plan is:

The astragalus polysaccharide is used as a raw material for the production of rumen regulators for ruminants.

The dosage of astragalus polysaccharide is 0.3-0.5g/L.

The dosage of astragalus polysaccharide is 0.5g/L or 0.3g/L.

Detailed ways

In order to make the objects and advantages of the present invention clearer, the present invention will be further described in detail below in conjunction with the examples. It should be understood that the specific embodiments described here are only used to explain the present invention, not to limit the present invention.

Example 1

The effects of different concentrations of astragalus polysaccharide (0, 0.1, 0.3 and 0.5 g/L) on rumen fermentation were studied by ruminant in vitro fermentation technology. Before morning feeding, rumen juice was collected from three different sites in the upper, middle and lower rumen of 3 cows with fistula, filtered through 4 layers of gauze, and then inoculated into fermentation bottles containing substrate and buffer at a ratio of 1:2. _CO2 was continuously injected into the fermentation bottle to adjust the pH to 6.8. After adding different concentrations of astragalus polysaccharides into the fermentation bottle, the bottle was sealed with a stopper. The fermentation bottle was connected with an automatic recording device for in vitro fermentation gas production through a gas conduit, and the device automatically recorded the amount of fermentation gas production in real time. The fermentation bottle was continuously cultured at 39°C for 72 hours. Each combination was repeated 3 times with 3 blank corrections. After fermentation, samples were taken to measure various enzyme activities, dry matter disappearance rate, volatile fatty acids, gas components and pH and other indicators. The specific experimental results are shown in the data in Tables 1, 2 and 3.

Table 1 Effect of adding astragalus polysaccharides on kinetic parameters of in vitro fermentation

Note: A is the gas production rate, B is the maximum gas production rate, C is the gas production rate, and D is the time taken to reach half of the maximum gas production rate. Different lowercase letters in the same row indicate significant differences (P<0.05).

Table 2 Effects of adding astragalus polysaccharides on the enzyme activities of in vitro fermentation

Note: Different lowercase letters in the same row indicate significant difference (P<0.05).

Table 3 Effect of adding astragalus polysaccharides on various parameters of in vitro fermentation

Note: Different lowercase letters in the same row indicate significant difference (P<0.05).

The above experimental data show that astragalus polysaccharides can effectively regulate rumen microbial fermentation of ruminants, promote feed utilization, and increase volatile acid production and microbial activity. And the effect of astragalus polysaccharide is the best when the amount of astragalus polysaccharide is 0.5g/L.

The above is only a preferred embodiment of the present invention, it should be pointed out that for those of ordinary skill in the art, without departing from the principle of the present invention, some improvements and modifications can also be made, and these improvements and modifications should also be It is regarded as the protection scope of the present invention.

Claims (5)

1. A use of astragalus polysaccharide, which is to use astragalus polysaccharide to regulate rumen microbial fermentation of ruminants. 2. The use of the astragalus polysaccharide as claimed in claim 1, characterized in that: the astragalus polysaccharide is used as a raw material for producing a rumen regulator for ruminants. 3. The use of astragalus polysaccharide according to claim 1 or 2, characterized in that: the dosage of astragalus polysaccharide is 0.3-0.5 g/L. 4. The use of astragalus polysaccharide as claimed in claim 3, characterized in that: the dosage of astragalus polysaccharide is 0.5g/L. 5. The use of astragalus polysaccharide as claimed in claim 3, characterized in that: the dosage of astragalus polysaccharide is 0.3g/L.