CN103893566A - Giant salamander Chinese herbal medicine compound preparation for treating hepatitis B - Google Patents
Giant salamander Chinese herbal medicine compound preparation for treating hepatitis B Download PDFInfo
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Abstract
The invention relates to a giant salamander Chinese herbal medicine compound preparation for treating hepatitis B. The preparation is prepared from giant salamander tissue and the following Chinese herbal medicines in parts by weight: 35-45 parts of medlar, 25-35 parts of lucid ganoderma, 10-14 parts of coptis chinensis, 13-16 parts of radix sophorae flavescentis, 10-14 parts of selfheal, 13-16 parts of radix scutellariae, 16-20 parts of isatis roots, 16-20 parts of honeysuckles, 8-12 parts of dendrobium officinale and 6-10 parts of ginseng, wherein the giant salamander tissue comprises 500-3000 parts of giant salamander liver and 5-9 giant salamander gallbladders. The preparation method of the preparation comprises the following steps: grinding and mixing the giant salamander tissue, steaming for 8-12 minutes at 85-95 DEG C and freezing to obtain a giant salamander tissue mixture; smashing medlar, lucid ganoderma, coptis chinensis, radix sophorae flavescentis, selfheal, radix scutellariae, isatis roots, honeysuckles, dendrobium officinale, ginseng and spiral seaweed to obtain a Chinese herbal medicine mixture; and mixing the giant salamander tissue mixture with the Chinese herbal medicine mixture. The preparation provided by the invention not only has a good antiviral performance, but also can effectively enhance the antigen binding affinity and the immunity to protect liver activity and promote recovery of damaged liver cells and the like. The preparation for treating hepatitis B is remarkable in curative effect.
Description
Technical field
The present invention relates to the preparation of Chinese herbal compound preparation, specifically, be to provide a kind of Chinese medicine preparation of the treatment hepatitis B that contains Andrias davidianus Blanchard active substance.
Background technology
Hepatitis B (abbreviation hepatitis B) is the liver inflammatory infringement being caused by hepatitis B virus (HBV), is a kind of infectious disease that China's current popular is the most extensive, harm is the most serious.Clinical manifestation is weak, loss of appetite, feels sick, vomits, detests oil, diarrhoea and abdominal distention, and part patient has heating, jaundice, approximately has the concealment of half patient onset, in the middle discovery of having a medical check-up.Abnormal liver function, serum hepatitis B performance antigen (HBSAg), hepatitis B virus DNA (deoxyribonucleic acid) are gathered (HBVDNA), hepatitis B virus immune globulin M (HBVIgM), deoxyribonucleic acid polymerase is all positive.Hepatitis B virus can not get controlling and removing at liver for a long time, and hepatic tissue cell infiltrates, necrosis, and the probability that finally forms liver cirrhosis and hepatocarcinoma is very large, therefore answer active treatment, stops virus replication, makes virus transfer resting state to.In treatment, doctor trained in Western medicine is mainly antiviral therapy, and antiviral drugs curative effect is still undesirable at present.The traditional Chinese medical science is thought, epidemic disease caused by damp-heat pathogen poison, and in pathogenic factor, soaking is the main reason of hepatitis B.Hepatitis B virus enters liver, makes depression of liver-QI, incoordination between the liver and spleen, and in the course of time, yang blood and qi is its wound extremely, and healthy energy can not resist its exopathogen, protracted course of disease; The strongly fragrant fire-transformation of a specified duration of dampness-heat of the liver, liver-yang consume; The spleen being the foundation of acquired constitution, is limited to liver, and liver disease affecting spleen; The kidney being the origin of congenital constitution, and The liver and the kidney have a common source, and prolonged illness must be empty, and nine diseases must be become silted up, and with the passing of time hepatopathy, certainly will involve liver spleen kidney and histoorgan.The desirable therapeutic scheme for the treatment of viral hepatitis being proposed by Wang Baixiang should be considered: (1) antiviral property.(2) antigen-binding activity.(3) immunoloregulation function.(4) liver protecting activities.It is to Chinese herbal medicine (Rhizoma Polygoni Cuspidati, Rhizoma Smilacis Glabrae, Herba Sedi, Herba Scutellariae Barbatae, Herba Hedyotidis Diffusae, Radix Paeoniae Rubra, Bombyx Batryticatus) compositing formula, research show to have anti-DHBV effect preferably (the experimentation outline of Counteracting Hepatitis B Virus by Chinese Herbal Drugs. the newly traditional Chinese medical science, 2001,33 (2): 3-5).But the medicine of existing treatment hepatitis B is take antiviral as main, the medicine for the treatment of hepatitis B that simultaneously possesses immunoloregulation function and liver protecting activities function is very rarely seen.And existing medicine (comprising Chinese medicine preparation) more or less exists side effect, therapeutic effect is not satisfactory.
Andrias davidianus Blanchard is commonly called as Megalobatrachus japonicus daoidianuas (Blanchard), is the distinctive rare medicinal amphibia animal of China, apart from the history of modern existing more than 300,000,000 year, has high nutritive value and important medical value.Andrias davidianus Blanchard just has in many ways as a kind of an aquatic animal medical material of recording since ancient times in Compendium of Material Medica, contain 50 various bioactivators and abundant polyunsaturated fatty acid, mainly contain eicosapentaenoic acid (EPA) and docosahexenoic acid (DHA), this series has the effect of fine raising immunity.In addition health-care effect very peculiar (containing one in Andrias davidianus Blanchard composition can kill hepatitis B virus, repair hepatocellular active substance) of the tissue such as Giant salamander skin secretion, Giant salamander bone, Andrias davidianus Blanchard liver, gallbladder internal organs.Existingly utilize the health product that Andrias davidianus Blanchard is made to have been reported, as Chinese patent discloses " a kind of Andrias davidianus Blanchard the kidney invigorating soft capsule and preparation method thereof " (201310110738.9), be mixed by Giant salamander oil, Megalobatrachus japonicus daoidianuas(Blanchard), Andrias davidianus Blanchard skin, Andrias davidianus Blanchard kidney, Ganoderma, Radix Notoginseng powder, Herba Herminii, Lentinus Edodes, Tricholoma matsutake (lto et lmai) Singer etc., there is strengthening the spleen and stomach, bone and muscle strengthening, wind-damp dispelling, fill blood, the effect such as cancer preventing and treating.The rarely seen report of medicine that utilizes Andrias davidianus Blanchard to make for major ingredient, the medicine containing giant salamander tissue that is used for the treatment of hepatitis B has no report.
Summary of the invention
Object of the present invention is just to provide a kind of compound Chinese medicinal preparation of the treatment hepatitis B that contains Andrias davidianus Blanchard composition, and it not only has antiviral functions, and has the function that improves immunologic function and the liver protecting activity, treatment hepatitis B successful.
For achieving the above object, embodiment of the present invention are: a kind of Andrias davidianus Blanchard compound Chinese medicinal preparation for the treatment of hepatitis B, formed by giant salamander tissue and prepared from traditional Chinese medicines, described Chinese herbal medicine comprises the raw material of following weight portion: Fructus Lycii 35-45 part, Ganoderma 25-35 part, Rhizoma Coptidis 10-14 part, Radix Sophorae Flavescentis 13-16 part, Spica Prunellae 10-14 part, Radix Scutellariae 13-16 part, Radix Isatidis 16-20 part, Flos Lonicerae 16-20 part, Herba Dendrobii 8-12 part, Radix Ginseng 6-10 part, described giant salamander tissue comprises the raw material of following weight portion: Andrias davidianus Blanchard liver 500-3000 part and Andrias davidianus Blanchard gallbladder 10-20 part.
Optimize, in described giant salamander tissue, also comprise Andrias davidianus Blanchard egg albumen powder 120-180 part, Andrias davidianus Blanchard secretions 100-500 part, Andrias davidianus Blanchard skin 1000-3000 part, in Chinese herbal medicine, also contain spirulina 18-22 part.
What further optimize is, raw material by following weight portion is made: 2000 parts of Andrias davidianus Blanchard livers, 15 parts, Andrias davidianus Blanchard gallbladder, 150 parts of Andrias davidianus Blanchard egg albumen powders, 200 parts of Andrias davidianus Blanchard secretions, 3000 parts of Andrias davidianus Blanchard skins, 40 parts of Fructus Lyciis, 30 parts of Ganodermas, 12 parts of Rhizoma Coptidis, 15 parts of Radix Sophorae Flavescentiss, 12 parts of Spica Prunellaes, 15 parts of Radix Scutellariae, 18 parts of Radix Isatidis, 18 parts of Flos Loniceraes, 10 parts of Herba Dendrobii, 8 parts of Radix Ginsengs, 20 parts of spirulinas.
Preparation method of the present invention is: giant salamander tissue defibrination mixed, steams 8-12 minute at 85-95 ℃,, freezing, obtain giant salamander tissue mixture; By Fructus Lycii, Ganoderma, Rhizoma Coptidis, Radix Sophorae Flavescentis, Spica Prunellae, Radix Scutellariae, Radix Isatidis, Flos Lonicerae, Herba Dendrobii, Radix Ginseng, spirulina part is pulverized, and obtains mixture of Chinese herbal medicines; Giant salamander tissue mixture is mixed with mixture of Chinese herbal medicines, make Emulsion.
By the lyophilization of above-mentioned giant salamander tissue mixture, mix with the mixture of Chinese herbal medicines of pulverizing, make powder;
By the lyophilization of above-mentioned giant salamander tissue mixture, mix with the mixture of Chinese herbal medicines of pulverizing, encapsulated, make capsule.
By the lyophilization of above-mentioned giant salamander tissue mixture, mix with the mixture of Chinese herbal medicines of pulverizing, add starch, compacting, makes tablet.
In the present invention, by analysis, Andrias davidianus Blanchard liver contains abundant bioactive substance and aminoglycan and Dan Baiduotang proteoglycan PG, and aminoglycan (HA) has another name called Hyaluronic Acid, and aminoglycan can promote cell proliferation, migration.Participate in embryo's generation, growth course.HA has important function repairing in the various physiological processes such as hepatitis B virus wound healing and tumor generation, and chemotactic and migration that can inflammation-inhibiting cell, suppress the generation of oxygen-derived free radicals.Megalobatrachus japonicus daoidianuas(Blanchard) (egg albumen powder) contains abundant polyunsaturated fatty acid, mainly contains linolenic acid, eicosapentaenoic acid (EPA) and docosahexenoic acid (DHA), and this series of biologic active substance has the effect of fine raising immunity.Andrias davidianus Blanchard gallbladder has effect of sterilization, liver heat removing and eyesight improving.Andrias davidianus Blanchard secretions and Andrias davidianus Blanchard skin not only have good cytothesis function, also have anti-inflammatory analgesic action.By zoopery, Andrias davidianus Blanchard also contains similar human stem cell material.Fructus Lycii has nourishing the liver, nourishing kidney,, effect of clearing away heat to improve acuity of vision, lycium barbarum polysaccharide has good adjusting immunization.Ganoderma has good protecting liver and detoxication effect.Rhizoma Coptidis, Radix Sophorae Flavescentis, Radix Scutellariae have heat clearing and damp drying, effect of eliminating fire and detoxication.There is effects such as letting out clearly liver-fire, mass dissipating and swelling eliminating, heat-clearing and toxic substances removing.Radix Isatidis, Flos Lonicerae have the function of good heat-clearing and toxic substances removing.Herba Dendrobii has removing toxic substances, improves effect of immunity.Radix Ginseng has the effect filling blood.Above-mentioned raw materials combination, not only has good antiviral property, and effectively enhancement antigen is in conjunction with activity and immunologic function, and the liver protecting activity, promotes the effects such as impaired hepatocyte recovery.Be used for the treatment of hepatitis B and there is obvious curative effects.
The specific embodiment
Embodiment 1:
A kind of important preparation for the treatment of hepatitis B, made by following raw material: 2000 grams of Andrias davidianus Blanchard livers, 15 grams, Andrias davidianus Blanchard gallbladder, 150 grams of Andrias davidianus Blanchard egg albumen powders, 200 grams of Andrias davidianus Blanchard secretions, 3000 grams of Andrias davidianus Blanchard skins, 40 grams of Fructus Lyciis, 30 grams of Ganodermas, 12 grams of Rhizoma Coptidis, 15 grams of Radix Sophorae Flavescentiss, 12 grams of Spica Prunellaes, 15 grams of Radix Scutellariae, 18 grams of Radix Isatidis, 18 grams of Flos Loniceraes, 10 grams of Herba Dendrobii, 8 grams of Radix Ginsengs, 20 grams of spirulinas.Described Andrias davidianus Blanchard egg albumen powder is Megalobatrachus japonicus daoidianuas(Blanchard) dry powder.Its preparation method is: Andrias davidianus Blanchard liver, Andrias davidianus Blanchard gallbladder, Andrias davidianus Blanchard secretions, Andrias davidianus Blanchard skin are knitted to defibrination and mix, steam 8-12 minute at 85-95 ℃, lyophilization, with Megalobatrachus japonicus daoidianuas(Blanchard) dry powder blend, obtains giant salamander tissue mixture; Fructus Lycii, Ganoderma, Rhizoma Coptidis, Radix Sophorae Flavescentis, Spica Prunellae, Radix Scutellariae, Radix Isatidis, Flos Lonicerae are pulverized, obtain mixture of Chinese herbal medicines; Giant salamander tissue mixture is mixed to sterilizing with mixture of Chinese herbal medicines, incapsulate, make capsule.
Embodiment 2:
A kind of important preparation for the treatment of hepatitis B, made by following raw material: 1000 grams of Andrias davidianus Blanchard livers, 10 grams, Andrias davidianus Blanchard gallbladder, 120 grams of Andrias davidianus Blanchard egg albumen powders, 300 grams of Andrias davidianus Blanchard secretions, 2000 grams of Andrias davidianus Blanchard skins, 45 grams of Fructus Lyciis, 25 grams of Radix Ginsengs, 14 grams of Rhizoma Coptidis, 13 grams of Radix Sophorae Flavescentiss, 14 grams of Spica Prunellaes, 13 grams of Radix Scutellariae, 20 grams of Radix Isatidis, 16 grams of Flos Loniceraes, 12 grams of Herba Dendrobii, 6 grams of Radix Ginsengs, described Andrias davidianus Blanchard egg albumen powder is the powder of Megalobatrachus japonicus daoidianuas(Blanchard) enzyme hydrolysis gained.Its preparation method is: Andrias davidianus Blanchard liver, Andrias davidianus Blanchard gallbladder, Andrias davidianus Blanchard secretions, Andrias davidianus Blanchard skin knitted to defibrination and mixes, steam 8-12 minute at 85-95 ℃, mix with Andrias davidianus Blanchard egg albumen powder, and freezing, obtain giant salamander tissue mix slurry; Fructus Lycii, Radix Ginseng, Rhizoma Coptidis, Radix Sophorae Flavescentis, Spica Prunellae, Radix Scutellariae, Radix Isatidis, Flos Lonicerae are pulverized, obtain mixture of Chinese herbal medicines; Giant salamander tissue mix slurry is mixed to sterilizing with mixture of Chinese herbal medicines, bottled, make Emulsion.
Embodiment 3:
A kind of Chinese medicine preparation for the treatment of hepatitis B, made by following raw material: 3000 grams of Andrias davidianus Blanchard livers, 20 grams, Andrias davidianus Blanchard gallbladder, 180 grams of Andrias davidianus Blanchard egg albumen powders, 100 grams of Andrias davidianus Blanchard secretions, 1000 grams of Andrias davidianus Blanchard skins, 35 grams of Fructus Lyciis, 35 grams of Ganodermas, 10 grams of Rhizoma Coptidis, 16 grams of Radix Sophorae Flavescentiss, 18 grams of Spica Prunellaes, 16 grams of Radix Scutellariae, 16 grams of Radix Isatidis, 20 grams of Flos Loniceraes, 8 grams of Herba Dendrobii, 10 grams of Radix Ginsengs, Andrias davidianus Blanchard egg albumen powder is made up of following methods: Megalobatrachus japonicus daoidianuas(Blanchard) is cooked, is dried, flour gained, pulverizes gained.The preparation method of this Chinese medicine preparation is: Andrias davidianus Blanchard liver, Andrias davidianus Blanchard gallbladder, Andrias davidianus Blanchard secretions, Andrias davidianus Blanchard skin are knitted to defibrination and mix, steam 8-12 minute at 85-95 ℃, mix with Andrias davidianus Blanchard egg albumen powder, lyophilization, obtains giant salamander tissue mixture; Fructus Lycii, Ganoderma, Rhizoma Coptidis, Radix Sophorae Flavescentis, Spica Prunellae, Radix Scutellariae, Radix Isatidis, Flos Lonicerae are pulverized, obtain mixture of Chinese herbal medicines; Giant salamander tissue mix slurry is mixed with mixture of Chinese herbal medicines, make routinely Chinese medicinal tablet requirement and add starch sterilizing, be pressed into tablet.
Embodiment 4:
A kind of Chinese medicine preparation for the treatment of hepatitis B, made by following raw material: 1500 grams of Andrias davidianus Blanchard livers, 12 grams, Andrias davidianus Blanchard gallbladder, 150 grams of Andrias davidianus Blanchard egg albumen powders, 40 grams of Fructus Lyciis, 15 grams of Ganodermas, 12 grams of Rhizoma Coptidis, 15 grams of Radix Sophorae Flavescentiss, 15 grams of Spica Prunellaes, 15 grams of Radix Scutellariae, 18 grams of Radix Isatidis, 18 grams of Flos Loniceraes, 11 grams of Herba Dendrobii, 9 grams of Radix Ginsengs.Described Andrias davidianus Blanchard egg albumen powder is Megalobatrachus japonicus daoidianuas(Blanchard) dry powder.Its preparation method is: organize defibrination to mix Andrias davidianus Blanchard liver, Andrias davidianus Blanchard gallbladder, Andrias davidianus Blanchard secretions, Andrias davidianus Blanchard skin, steam 8-12 minute at 85-95 ℃, lyophilization, with Megalobatrachus japonicus daoidianuas(Blanchard) dry powder blend, obtains giant salamander tissue mixture; Fructus Lycii, Ganoderma, Rhizoma Coptidis, Radix Sophorae Flavescentis, Spica Prunellae, Radix Scutellariae, Radix Isatidis, Flos Lonicerae, Herba Dendrobii, Radix Ginseng are pulverized, obtained mixture of Chinese herbal medicines; Giant salamander tissue mixture is mixed to sterilizing with mixture of Chinese herbal medicines, incapsulate, make capsule.
Embodiment 5:
Treat a Chinese medicine preparation for hepatitis B, made by following raw material: 20 grams of 2000 grams of Andrias davidianus Blanchard livers, Andrias davidianus Blanchard gallbladder 8 (15-18 gram), 300 grams of Andrias davidianus Blanchard egg albumen powders, 500 grams of Andrias davidianus Blanchard secretions, 40 grams of Fructus Lyciis, 12 grams of Rhizoma Coptidis, 15 grams of Radix Sophorae Flavescentiss, 12 grams of Spica Prunellaes, 15 grams of Radix Scutellariae, 18 grams of Radix Isatidis, 18 grams of Flos Loniceraes, 11 grams of Herba Dendrobii, Radix Ginseng 15, spirulina.Described Andrias davidianus Blanchard egg albumen powder is Megalobatrachus japonicus daoidianuas(Blanchard) dry powder.Its preparation method is: organize defibrination to mix Andrias davidianus Blanchard liver, Andrias davidianus Blanchard gallbladder, Andrias davidianus Blanchard secretions, Andrias davidianus Blanchard skin, steam 8-12 minute at 85-95 ℃, lyophilization, with Megalobatrachus japonicus daoidianuas(Blanchard) dry powder blend, obtains giant salamander tissue mixture; Fructus Lycii, Ganoderma, Rhizoma Coptidis, Radix Sophorae Flavescentis, Spica Prunellae, Radix Scutellariae, Radix Isatidis, Flos Lonicerae, spirulina are pulverized, obtained mixture of Chinese herbal medicines; Giant salamander tissue mixture is mixed with mixture of Chinese herbal medicines, incapsulate, make capsule.
The finished product of above 1-5 embodiment will be preserved more than-5 ℃, and the shelf-life is 6 months.
Embodiment 1 is preferred version.
Now treat hepatitis B patient 126 examples with the present invention, be reported as follows:
1, case selection: totally 126 examples, wherein male 72 examples, female's 54 examples, age 15-66 year.
2, diagnostic criteria: serum hepatitis B performance antigen (HBSAg), hepatitis B virus DNA (deoxyribonucleic acid) are gathered (HBVDNA), hepatitis B virus immune globulin M (HBVIgM), deoxyribonucleic acid polymerase is all positive, abnormal liver function, have weak, loss of appetite, feel sick, detest the symptoms such as greasy, diarrhoea and abdominal distention, some cases has jaundice heating.
3, ingredients: see foregoing embodiments.
4, Therapeutic Method: oral, sooner or later respectively once, each 10-15 gram, two months is a course for the treatment of.Can fully recover general 3 courses for the treatment of, and can fully recover severe one 5-6 the course for the treatment of.During treatment, fasting maror and Smoking And Drinking.
5, curative effect judging standard: (1) cures: liver function is normal, and big and small three Yang is normal, transference cure; (2) take a turn for the better: liver function is normal, and great three positive transfers small three positive to, symptom part disappears: (3) are invalid: symptom is without improvement, and liver function is without improvement, and big and small three Yang is without change.
6, curative effect statistics
The present invention adopts Andrias davidianus Blanchard corium, secretions, liver, gallbladder and Andrias davidianus Blanchard bioactive substance; make with Chinese herbal medicine such as Ganoderma, Rhizoma Coptidis, Spica Prunellae, Radix Isatidis, Flos Loniceraes; there is the effects such as clearing away heat-damp and promoting diuresis, strong liver kidney tonifying, strengthening the body resistance, mass dissipating and swelling eliminating; there is the function of antiviral property, antigen-binding activity, immunoloregulation function and liver protecting activities simultaneously; be used for the treatment of hepatitis B; effective percentage reaches 92.8%, and obvious effective rate reaches 65.1%.
Claims (7)
1. treat the Andrias davidianus Blanchard compound Chinese medicinal preparation of hepatitis B for one kind, it is characterized in that, formed by giant salamander tissue and prepared from traditional Chinese medicines, described Chinese herbal medicine comprises the raw material of following weight portion: Fructus Lycii 35-45 part, Ganoderma 25-35 part, Rhizoma Coptidis 10-14 part, Radix Sophorae Flavescentis 13-16 part, Spica Prunellae 10-14 part, Radix Scutellariae 13-16 part, Radix Isatidis 16-20 part, Flos Lonicerae 16-20 part, Herba Dendrobii 8-12 part, Radix Ginseng 6-10 part, described giant salamander tissue comprises the raw material of following weight portion: Andrias davidianus Blanchard liver 500-3000 part and Andrias davidianus Blanchard gallbladder 10-20 part.
2. the Andrias davidianus Blanchard compound Chinese medicinal preparation for the treatment of hepatitis B according to claim 1, it is characterized in that, in described giant salamander tissue, also comprise Andrias davidianus Blanchard egg albumen powder 120-180 part, Andrias davidianus Blanchard secretions 100-500 part, Andrias davidianus Blanchard skin 1000-3000 part, in Chinese herbal medicine, also contain spirulina 18-22 part.
3. the Andrias davidianus Blanchard compound Chinese medicinal preparation for the treatment of hepatitis B according to claim 2, it is characterized in that, made by the raw material of following weight portion: 2000 parts of Andrias davidianus Blanchard livers, 15 grams, Andrias davidianus Blanchard gallbladder, 150 parts of Andrias davidianus Blanchard egg albumen powders, 200 parts of Andrias davidianus Blanchard secretions, 3000 parts of Andrias davidianus Blanchard skins, 40 parts of Fructus Lyciis, 30 parts of Ganodermas, 12 parts of Rhizoma Coptidis, 15 parts of Radix Sophorae Flavescentiss, 12 parts of Spica Prunellaes, 15 parts of Radix Scutellariae, 18 parts of Radix Isatidis, 18 parts of Flos Loniceraes, 10 parts of Herba Dendrobii, 8 parts of Radix Ginsengs, 20 parts of spirulinas.
4. a preparation method for the Andrias davidianus Blanchard compound Chinese medicinal preparation for the treatment of hepatitis B as claimed in claim 1, is characterized in that, giant salamander tissue defibrination is mixed, and steams 8-12 minute at 85-95 ℃, freezing, obtains giant salamander tissue mixture; Chinese herbal medicine is pulverized, obtained mixture of Chinese herbal medicines; Giant salamander tissue mixture is mixed with mixture of Chinese herbal medicines, make Emulsion.
5. the preparation method of the Andrias davidianus Blanchard compound Chinese medicinal preparation for the treatment of hepatitis B according to claim 4, is characterized in that, by the lyophilization of above-mentioned giant salamander tissue mixture, mixes with the mixture of Chinese herbal medicines of pulverizing, and makes powder.
6. the preparation method of the Andrias davidianus Blanchard compound Chinese medicinal preparation for the treatment of hepatitis B according to claim 4, is characterized in that, by the lyophilization of above-mentioned giant salamander tissue mixture, mixes with the mixture of Chinese herbal medicines of pulverizing, encapsulated, makes capsule.
7. the preparation method of the Andrias davidianus Blanchard compound Chinese medicinal preparation for the treatment of hepatitis B according to claim 4, is characterized in that, by the lyophilization of above-mentioned giant salamander tissue mixture, mixes with the mixture of Chinese herbal medicines of pulverizing, and adds starch, and compacting, makes tablet.
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| CN104688937A (en) * | 2015-03-17 | 2015-06-10 | 贵阳学院 | Chinese herbal compound preparation of giant salamander for oncologic nursing and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104688937A (en) * | 2015-03-17 | 2015-06-10 | 贵阳学院 | Chinese herbal compound preparation of giant salamander for oncologic nursing and preparation method thereof |
| CN104688937B (en) * | 2015-03-17 | 2019-02-15 | 贵阳学院 | A kind of giant salamander traditional Chinese medicine compound preparation for tumor nursing and preparation method thereof |
| CN104645082A (en) * | 2015-03-23 | 2015-05-27 | 傅宇晓 | Capsule for treating hepatitis and preparation method thereof |
| CN104645082B (en) * | 2015-03-23 | 2017-12-15 | 应瑶琪 | A kind of capsule for treating hepatitis and preparation method thereof |
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