CN103893460A - Traditional Chinese medicine composition for treating diabetic nephropathy - Google Patents
Traditional Chinese medicine composition for treating diabetic nephropathy Download PDFInfo
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- CN103893460A CN103893460A CN201410138500.1A CN201410138500A CN103893460A CN 103893460 A CN103893460 A CN 103893460A CN 201410138500 A CN201410138500 A CN 201410138500A CN 103893460 A CN103893460 A CN 103893460A
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- 208000007342 Diabetic Nephropathies Diseases 0.000 title claims abstract description 16
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Abstract
The invention discloses a traditional Chinese medicine composition for treating diabetic nephropathy. The diabetic nephropathy has symptoms of subdue thirsty diseases, subsiding swelling, diabetes involving the lower warmer, edema and the like in traditional Chinese medicine, and the diabetic nephropathy can cause Qi consuming and Yin injuring with the passing of time, Yin deficiency affecting Yang, deficiency of both Qi and Yin, Yin-Yang deficiency, chronic diseases transforming to collaterals, phlegm, pathogenic heat, blood stasis, and obstruction of the circulation of vital energy and lead to micro abdominal mass, thus resulting in injury on kidney and dysfunction of kidney. The traditional Chinese medicine composition for treating diabetic nephropathy is characterized in that the traditional Chinese medicines capable of dredging channels and tonifying kidney, nourishing Yin and tonifying Yang, promoting blood circulation to remove blood stasis, and clearing heat and promoting dieresis are selected and prepared into decoction, wherein the traditional Chinese medicines selected include rhizoma drynariae, root of wallich swallowwort, oriental waterplantain fruit, tinospora sinensis, caragana microphylla, rhizome of david woodbetony, woody-rhizomed fimbristylis herb, eleutherococcus senticosus, campsis grandiflora and rubia yunnanensis. The clinic test shows that the traditional Chinese medicine composition has an obvious treatment effect, the total effective rate reaches 94.6%, the treatment cost is low, and the method is simple and convenient.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, relate in particular to a kind of Chinese medicine composition for the treatment of diabetic nephropathy.
Background technology
Diabetic nephropathy (diabet ic nephropathy, DN) be a kind of chronic complicating diseases of the serious and hazardness maximum that causes of diabetes, it is one of diabetes general microangiopathies performance, Clinical symptoms is albuminuria, gradual renal function injury, hypertension, edema, occurring severe renal nonfunction late period, is one of major causes of death of diabetics.Western medical treatment is many at present sets about from aspects such as diet control, strengthening glycemic control, blood pressure lowering, adjustment lipid metabolism, or adopts the treatment meanss such as dialysis, renal transplantation, although effectively, but bring heavy financial burden to patient, Chinese traditional treatment has rich experience, successful, do not need Long-term taking medicine, no dependence, entirety is dialectical, individuality treats, promote pancreatic cell regeneration ability, human internal organ is in harmonious proportion, equilibrium between yin and yang, recover benign cycle, obtain good therapeutic effect.Treatment by Chinese herbs also has price low in addition, has no side effect, and is difficult for the advantages such as recurrence.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine composition for the treatment of diabetic nephropathy.Diabetic nephropathy belongs to that motherland's medical science is quenched one's thirst, diabetes involving the kidney, under disappear, the category such as edema.Chinese medicine is thought: diabetic nephropathy is with the passing of time yin-damaging and Qi consumings of diabetes, deficiency of YIN affecting YANG, and deficiency of both QI and YIN, deficiency of both YIN and YANG, pathogen usually intruding into collateral in protracted disease, expectorant is turbid, pathogenic heat, blood stasis, the stagnation of QI are cementing mutually, forms " miniature lump in the abdomen ", makes kidney body impaired, and kidney is with due to mistake department.The suitable dredging collateral kidney tonifying of Chinese traditional treatment, nourishing YIN and invigorating YANG, blood circulation promoting and blood stasis dispelling, clearing away heat-damp and promoting diuresis.
Treat a Chinese medicine composition for diabetic nephropathy, this Chinese medicine composition is made up of the Chinese medicine of following weight portion: Rhizoma Drynariae 6-9 part, Radix cynanchi wallichii 30-40 part, Fructus Alismatis 6-9 part, Caulis Tinosporae 9-15 part, Herba Caraganae intermediae 9-15 part, Radix Antiotrematis dunniani 9-15 part, Radix Fimbristylis rigidulae 9-15 part, Radix Kalopanacis 15-25 part, Flos Campsis 6-9 part, Radix Rubiae Yunnanensis 9-15 part.
Preferably, 7.5 parts of Rhizoma Drynariae, 35 parts of Radix cynanchi wallichiis, 7 parts of Fructus Alismatiss, 12 parts of Caulis Tinosporaes, 12 parts of Herba Caraganae intermediaes, 12 parts of Radix Antiotrematis dunnianis, 12 parts of Radix Fimbristylis rigidulaes, 20 parts of Radix Kalopanacis, 7 parts of Flos Campsiss, 12 parts of Radix Rubiae Yunnanensis.
Above-mentioned Chinese medicine decocting is made decoction by preparation method.
In side: Rhizoma Drynariae invigorating kidney, promoting blood circulation; Radix cynanchi wallichii Bu Shen Zhuang waist, bone and muscle strengthening; Fructus Alismatis kidney tonifying gas, YIN nourishing are quenched one's thirst, wind-damp dispelling; Caulis Tinosporae relaxing muscles and tendons and activating QI and blood in the collateral, clearing away heat-damp and promoting diuresis; Herba Caraganae intermediae nourishing the blood and yin; Radix Antiotrematis dunniani yin nourishing tonify deficiency, heat-clearing and toxic substances removing; Radix Fimbristylis rigidulae is nourshing Yin and drynsessmoistening prescription, the beneficial damage of tonify deficiency; Radix Kalopanacis dissipating blood stasis removing heat from blood, expelling wind and removing dampness; Flos Campsis promoting the circulation of blood blood stasis removing, cooling blood, expelling wind; Radix Rubiae Yunnanensis blood circulation promoting and enriching, expelling wind and removing dampness.
Clinical data
1, the routine patient of physical data 37 all meets diabetic nephropathy diagnostic criteria, wherein male 20 examples, female's 17 examples, 20～62 years old age, average 48.5 years old, the course of disease 1 year～10 years.
2, the diabetics that diagnostic criteria (1) has diabetic history and fails to be effectively controlled.(2) fasting glucose rising or glucose tolerance test are abnormal.(3) there is the clinical manifestation of nephritis or nephrotic syndrome, accompanied with hypertension, glomerular filtration rate reduces.(4) at the bottom of companion's diabetic eye, change.(5) microdose urine protein, urinary albumin excretion ratio (UAE) >30mg/dl.(6) kidney biopsy contributes to early diagnosis.
3, Therapeutic Method patient takes Chinese medicine composition of the present invention, takes Rhizoma Drynariae 7.5g, Radix cynanchi wallichii 35g, Fructus Alismatis 7g, Caulis Tinosporae 12g, Herba Caraganae intermediae 12g, Radix Antiotrematis dunniani 12g, Radix Fimbristylis rigidulae 12g, Radix Kalopanacis 20g, Flos Campsis 7g, Radix Rubiae Yunnanensis 12g.Decocting becomes decoction, and potion, divided early, took for 2 times evening every day, and surrounding is a course for the treatment of, takes continuously two courses for the treatment of.
4, criterion of therapeutical effect is effective: clinical cardinal symptom disappears, and chemical examination renal function, blood glucose are normal, glucose in urine+following; Effective: clinical symptom relief or improvement, chemical examination normal renal function, blood glucose is slightly high, and glucose in urine exists ++ and following; Invalid: clinical symptoms is unchanged, laboratory indexes is with before treating.
5, observe the curative effect after 2 courses for the treatment of of therapeutic outcome treatment, 37 routine patients, effective 21 examples (56.8%), effective 14 examples (37.8%), invalid 2 examples (5.4%), total effective rate 94.6%, in therapeutic process, patient has no untoward reaction.Therapeutic outcome shows that Chinese medicine composition of the present invention has significant curative effect aspect treatment diabetic nephropathy.
The specific embodiment
Embodiment mono-: take Rhizoma Drynariae 7.5g, Radix cynanchi wallichii 35g, Fructus Alismatis 7g, Caulis Tinosporae 12g, Herba Caraganae intermediae 12g, Radix Antiotrematis dunniani 12g, Radix Fimbristylis rigidulae 12g, Radix Kalopanacis 20g, Flos Campsis 7g, Radix Rubiae Yunnanensis 12g, above-mentioned Chinese medicine decocting is become to decoction.
Embodiment bis-: take Rhizoma Drynariae 6g, Radix cynanchi wallichii 30g, Fructus Alismatis 9g, Caulis Tinosporae 9g, Herba Caraganae intermediae 15g, Radix Antiotrematis dunniani 9g, Radix Fimbristylis rigidulae 15g, Radix Kalopanacis 25g, Flos Campsis 9g, Radix Rubiae Yunnanensis 9g, above-mentioned Chinese medicine decocting is become to decoction.
Embodiment tri-: take Rhizoma Drynariae 9g, Radix cynanchi wallichii 40g, Fructus Alismatis 6g, Caulis Tinosporae 15g, Herba Caraganae intermediae 9g, Radix Antiotrematis dunniani 15g, Radix Fimbristylis rigidulae 9g, Radix Kalopanacis 15g, Flos Campsis 6g, Radix Rubiae Yunnanensis 15g, above-mentioned Chinese medicine decocting is become to decoction.
Claims (2)
1. treat a Chinese medicine composition for diabetic nephropathy, it is characterized in that this Chinese medicine composition is made up of the Chinese medicine of following weight portion: Rhizoma Drynariae 6-9 part, Radix cynanchi wallichii 30-40 part, Fructus Alismatis 6-9 part, Caulis Tinosporae 9-15 part, Herba Caraganae intermediae 9-15 part, Radix Antiotrematis dunniani 9-15 part, Radix Fimbristylis rigidulae 9-15 part, Radix Kalopanacis 15-25 part, Flos Campsis 6-9 part, Radix Rubiae Yunnanensis 9-15 part.
2. a kind of Chinese medicine composition for the treatment of diabetic nephropathy according to claim 1, is characterized in that this Chinese medicine composition is made up of the Chinese medicine of following weight portion: 7.5 parts of Rhizoma Drynariae, 35 parts of Radix cynanchi wallichiis, 7 parts of Fructus Alismatiss, 12 parts of Caulis Tinosporaes, 12 parts of Herba Caraganae intermediaes, 12 parts of Radix Antiotrematis dunnianis, 12 parts of Radix Fimbristylis rigidulaes, 20 parts of Radix Kalopanacis, 7 parts of Flos Campsiss, 12 parts of Radix Rubiae Yunnanensis.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410138500.1A CN103893460A (en) | 2014-03-30 | 2014-03-30 | Traditional Chinese medicine composition for treating diabetic nephropathy |
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| CN201410138500.1A CN103893460A (en) | 2014-03-30 | 2014-03-30 | Traditional Chinese medicine composition for treating diabetic nephropathy |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102302673A (en) * | 2011-09-02 | 2012-01-04 | 西南大学 | Traditional Chinese medicine compound preparation for preventing and treating diabetic nephropathy (DN) |
| CN103599360A (en) * | 2013-11-05 | 2014-02-26 | 王焕江 | Traditional Chinese medicament for treating diabetic nephropathy |
| CN103638389A (en) * | 2013-12-24 | 2014-03-19 | 山东省中医药研究院 | Traditional Chinese medicine composition for treating diabetes |
-
2014
- 2014-03-30 CN CN201410138500.1A patent/CN103893460A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102302673A (en) * | 2011-09-02 | 2012-01-04 | 西南大学 | Traditional Chinese medicine compound preparation for preventing and treating diabetic nephropathy (DN) |
| CN103599360A (en) * | 2013-11-05 | 2014-02-26 | 王焕江 | Traditional Chinese medicament for treating diabetic nephropathy |
| CN103638389A (en) * | 2013-12-24 | 2014-03-19 | 山东省中医药研究院 | Traditional Chinese medicine composition for treating diabetes |
Non-Patent Citations (2)
| Title |
|---|
| 张克香: ""破血益肾降浊汤治疗糖尿病肾病V期30例"", 《中国医药指南》 * |
| 王洪武 等: ""中药治疗糖尿病肾病用药规律探讨"", 《中华中医药学刊》 * |
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Application publication date: 20140702 |
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