CN103877484A - Traditional Chinese medicine oral liquid for treating oral liquid - Google Patents
Traditional Chinese medicine oral liquid for treating oral liquid Download PDFInfo
- Publication number
- CN103877484A CN103877484A CN201410123823.3A CN201410123823A CN103877484A CN 103877484 A CN103877484 A CN 103877484A CN 201410123823 A CN201410123823 A CN 201410123823A CN 103877484 A CN103877484 A CN 103877484A
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- semen
- fructus
- parched
- radix
- oral liquid
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Abstract
The invention discloses a traditional Chinese medicine oral liquid for treating chronic enteritis. The preparation disclosed by the invention is a composition liquid preparation which is prepared by the following steps: smashing, decocting, ethanol-extracting and mixing agastache rugosus, medicated leaven, white hyacinth beans, fructus forsythiae, poria cocos, semen raphani, radix bupleurim, caulis bambusae in taeniam, cinnamon, fructus amomi, elecampane, scorched hawthorn fruits, colored malts, coptis chinensis, semen coicis, scutellaria baicalensis, cistanche, bletilla, millets and the like. The oral liquid disclosed by the invention is remarkable in effect of treating chronic enteritis. The composition obtained by drug matching and preparation method effectively achieves the function of regulating the intestinal tract and internal organs of the body by a dialectical method, and the preparation is free from toxic and side effects and stable in effect, and has the curative effect of yielding twice the result with half the effort compared with that of western medicines.
Description
Technical field
The present invention relates to a kind of Chinese medicine oral liquid for the treatment of chronic enteritis, be specifically related to Chinese medicine oral liquid of this treatment chronic enteritis and preparation method thereof.
Background technology
Intestinal refers to the digestive tube from stomach pylorus to anus, and intestinal is one section the longest in digestive tube, is also most important one section of function.Intestinal is the digestive organs of human body maximum, is also the toxin expelling organ of human body maximum.From physiology, anatomy, cytological angle, large intestine toxin expelling accounts for the more than 85% of human detoxification; 80% immune structure of human body is around intestinal, and endotoxic accumulation is the killer of autoimmune power.
Enteritis mainly refers to gastroenteritis, enteritis and colitis, is commonly considered as being caused by antibacterial, virus, fungus and parasite etc.That clinical main manifestations has is nauseating, vomiting, stomachache, diarrhoea, stool viscous band blood, defecate shapelessly, and part patient can have heating and tenesmus sensation.In recent years, along with the raising of people's living standard and the change of life style, the sickness rate of chronic enteritis is in rising trend, and this disease course of disease is longer, be difficult to radical cure, repeatedly outbreak, having a strong impact on people's healthy and quality of life, and canceration rate reaches 5% left and right.Although it is not very few to be used for the treatment of at present the medicine of enteritis, Western medicine is cured the symptoms, not the disease, and has used of a specified duration and has easily developed immunity to drugs, and side effect is larger, infringement liver, kidney and hemocyte, and also drug effect is unstable, easily outbreak repeatedly.
Summary of the invention
Object of the present invention is for above-mentioned deficiency, on the basis of secret prescription handed down in the family from generation to generation, in conjunction with modern Chinese and western medicine technology, a kind of Chinese medicine oral liquid for the treatment of chronic enteritis is provided, is to provide specifically this Chinese medicine oral liquid and preparation method thereof, enteritis therapeutic effect of the present invention is obvious, and nontoxic, have no side effect, effect stability, reparation technology is simple and easy to do.
Technical scheme of the present invention is as described below:
Preparation of the present invention is the composite preparation being prepared into by Herba Pogostemonis, six songs, Semen Lablab Album, Fructus Forsythiae, Poria, Semen Raphani, Radix Bupleuri, Caulis Bambusae In Taenia, Cortex Cinnamomi, Fructus Amomi, the Radix Aucklandiae, Fructus Crataegi (parched to brown), Fructus Hordei Germinatus (parched), Rhizoma Coptidis, Semen Coicis, Radix Scutellariae, Herba Cistanches, the Pseudobulbus Bletillae (Rhizoma Bletillae) and Semen setariae, and wherein the quality proportioning of each component is:
The bent 10-22g Semen Lablab Album of Herba Pogostemonis 12-20g six 8-18g
Fructus Forsythiae 10-18g Poria 8-15g Semen Raphani 10-20g
Radix Bupleuri 8-16g Caulis Bambusae In Taenia 12-20g Cortex Cinnamomi 8-16g
Fructus Amomi 10-18g Radix Aucklandiae 10-18g Fructus Crataegi (parched to brown) 10-18g
Fructus Hordei Germinatus (parched) 8-15g Rhizoma Coptidis 6-15g Semen Coicis 8-15g
Radix Scutellariae 10-18g Herba Cistanches 8-16g Pseudobulbus Bletillae (Rhizoma Bletillae) 8-15g
Semen setariae 10-20g.
In order to obtain better effect, the present invention preferably raw material mass mixture ratio is:
The bent 10-18g Semen Lablab Album of Herba Pogostemonis 12-18g six 8-12g
Fructus Forsythiae 12-18g Poria 8-12g Semen Raphani 10-15g
Radix Bupleuri 8-12g Caulis Bambusae In Taenia 12-16g Cortex Cinnamomi 8-12g
Fructus Amomi 10-15g Radix Aucklandiae 10-14g Fructus Crataegi (parched to brown) 10-15g
Fructus Hordei Germinatus (parched) 8-12g Rhizoma Coptidis 6-10g Semen Coicis 8-12g
Radix Scutellariae 10-15g Herba Cistanches 8-12g Pseudobulbus Bletillae (Rhizoma Bletillae) 8-12g
Semen setariae 12-18g.
Certainly, in order to obtain further good effect, the present invention also preferably raw material mass mixture ratio be:
The bent 12g Semen Lablab Album of Herba Pogostemonis 15g six 9g
Fructus Forsythiae 15g Poria 10g Semen Raphani 12g
Radix Bupleuri 12g Caulis Bambusae In Taenia 10g Cortex Cinnamomi 8g
Fructus Amomi 12g Radix Aucklandiae 14g Fructus Crataegi (parched to brown) 12g
Fructus Hordei Germinatus (parched) 8g Rhizoma Coptidis 8g Semen Coicis 12g
Radix Scutellariae 10g Herba Cistanches 8g Pseudobulbus Bletillae (Rhizoma Bletillae) 10g
Semen setariae 15g.
The preparation method of above-mentioned treatment chronic enteritis Chinese medicine, comprises the steps:
1), six songs put into pannikin carry out stir-fry dish cooked in a small wok, meaning the food is prepared with special care 2-3 minute, then pulverize and cross 80 mesh sieves through pulverizer, for subsequent use;
2), Herba Pogostemonis, Semen Lablab Album, Fructus Forsythiae, Poria, Radix Bupleuri, Caulis Bambusae In Taenia, Cortex Cinnamomi, Semen setariae, Radix Scutellariae, Herba Cistanches are prepared in proportion, be ground into powder and cross 90 mesh sieves through pulverizer, naturally drying, for subsequent use;
3), by step 1) and 2) in each component powders mix, add pure water to decoct twice, add for the first time 10 times of pure water to decoct 1 hour, extract filtrate for later use; Add for the second time 6 times of pure water to decoct half an hour, then collecting decoction filtration, for subsequent use;
4), remaining Semen Raphani, Fructus Amomi, the Radix Aucklandiae, Fructus Crataegi (parched to brown), Fructus Hordei Germinatus (parched), Rhizoma Coptidis, Semen Coicis, the Pseudobulbus Bletillae (Rhizoma Bletillae) are prepared in proportion, be ground into powder and cross 80 mesh sieves through pulverizer, naturally drying, for subsequent use;
5), each component powders in step 4) is mixed, add the ethanol of 4～6 times 70%～80%, reflux 3～5 hours, extracts to filter and obtains filtrate; Then in remaining medicinal residues, again add the ethanol of 2～4 times 65%～75%, reflux 2～3 hours, extracts and filters acquisition filtrate; The filtrate of twice acquisition is combined, and concentrating under reduced pressure is removed alcohol solvent, dry, obtains and gets dry extract;
6), by above-mentioned steps 5) in the dry cream that obtains carry out micronizing powdered and cross 200 mesh sieves, then powder is added to 3) collecting decoction in step, mix and shake up and can make.
The above-mentioned Chinese medicine composition pharmaceutical solutions of producing can be for oral, if can each also long-term drink, better effects if of drinking in right amount once of morning, noon and afternoon.
Theoretical foundation of the present invention is:
Herba Pogostemonis, slightly warm in nature, acrid-sweet flavor, there is removing dampness by means of aromatics, deliver expelling summer-heat, inducing diaphoresis to expel pathogens, dampness removing except wind, relieve heat and thirst, stomach function regulating preventing or arresting vomiting, fast gas and in, the effect such as stomach invigorating damp eliminating.Be generally used for the diseases such as treatment is had a headache and fever, anemofrigid cold, abdominal distention uncomfortable in chest, cold syndrome of the stomach pain, vomiting, dysentery, halitosis.
Burnt six songs, sweet in the mouth, pungent, warm in nature, can help digestion, stomach invigorating, for dyspepsia, dyspeptic abdominal distention, diarrhoea, this product is the processed goods forming through fermentation after adopting Semen Armeniacae Amarum mud, Semen Phaseoli, Herba polygoni hydropiperis, Herba Artemisiae Annuae, flour, Herba Xanthii grass medicamental pulverata to mix, play in the present invention QI and blood regulating weak, disorder of stomach-QI, can not diet, and food does not often disappear, a little less than extremity Costumes, hundred diseases are handed over the effect of attacking.
The pharmacological action of Semen Lablab Album in preparation of the present invention is mainly antibacterial, antiviral, and experiment shows: the dull and stereotyped paper disk method of 100% Semen Lablab Album decoct, to dysentery bacterium with there is an inhibitory action; Vomiting, acute gastroenteritis etc. that alimentary toxicosis is caused have Detoxication.Semen Lablab Album water extract has inhibitory action to mice Columbia SK virus.
Fructus Forsythiae, bitter in the mouth, cold nature, is Oleaceae forsythia, and Fructus Forsythiae first leaf in early spring is bloomed, and the flowers are in blossom, and fragrance is light gorgeous, and full branch is golden yellow, gorgeous lovely, is good sight flowering shrub in early spring, and fruit can be used as medicine.Fructus Forsythiae is mainly containing compounds such as phenethyl alcohol glycosides, lignan and glycoside thereof, pentacyclic triterpene Lou, volatile oils.Pharmacological research thinks that it has antibacterial, antiinflammatory, antipyretic, tell in town, diuresis heart tonifying, anti-liver damage, analgesia, suppress the effects such as phosphodiesterase, antiviral, blood pressure lowering, inhibition elastin laminin enzyme activity, antiendotoxin.Except fruit medicine, outside the effect of tool heat-clearing and toxic substances removing, the knot evacuation of pus that disappears, medicinal its leaf, better to treatment hypertension, dysentery, throat pain texts.The pharmacological action such as that Fructus Forsythiae has is antibacterial, heart tonifying, diuresis, town are told, is the Chinese medicine of heat-clearing and toxic substances removing, cures mainly calentura from the beginning of symptom, its bacteriostasis and Flos Lonicerae broadly similars such as, anemopyretic cold, heating, vexed, laryngopharynx swelling and pain, acute nephritis, carbuncle sore tumefacting virus.
Poria, the main component in Poria is pachyman, content is very high.Various bacteria is had to inhibitory action; Can fall gastric acid, digestive tract ulcer is had to preventive effect; Hepatic injury is had to significant protective effect; There is antineoplastic action; Can many-sided immunologic function be regulated; Can make leukopenia due to chemotherapy accelerate; And there is a calm effect.
Semen Raphani, property is flat, acrid in the mouth, sweet.Return lung, spleen, stomach warp, cure mainly the de-swelling that helps digestion, lowering the adverse-rising QI to resolve phlegm.Cure mainly stagnation of QI due to dyspepsia, distension and fullness in the abdomen, belch, heavy after dysentery, cough with copious phlegm, dyspnea with rapid and short breath fullness in the chest, the de-swelling that can help digestion, effect is remarkable, has the title of " rush wall fall wall ".Clinical habit is used for the treatment of, and real (food, wet, stagnant) demonstrate,proved.But these product are not only the de-swellings that helps digestion, and deficiency syndrome, with it, are obtained to effect also good, because of its property peace, its abnormal smells from the patient is not high again, and what without the fraud of victory partially, can not be limited to " rush wall fall wall " says there is the suspicion (being having a surplus of flat gas actually) of dispelling the stagnated QI, and gives it up.
Radix Bupleuri, bitter in the mouth, pungent, cold nature; Return liver, gallbladder meridian; Micro-fragrant liter fallen apart; There is clearing away heat and expelling pathogen in the exterior, treating SHAO YANG disease by mediation, dispersing the stagnated live-QI to relieve the stagnation of QI, effect of ascending up spleen-Qi and Yang, cure mainly fever caused by exogenous pathogens, alternate attack of chill and fever, malaria, jaundice, distending pain in the chest and hypochondrium, headache conjunctival congestion, deaf bitter taste, menoxenia, visceroptosis, the proctoptosis prolapse of the uterus, recklessly can dispersing the stagnated live-QI to relieve the stagnation of QI, and joining resistance and supplementing qi medicine can ascending up spleen-Qi and Yang, for uterine prolapse, proctoptosis, so without the merit of promoting the production of body fluid and quenching one's thirst; Radix Puerariae has promoting the production of body fluid to quench thirst effect, and energy hair growth promoting sun clearly, for watery diarrhea, so without dispersing the stagnated live-QI to relieve the stagnation of QI function.
Caulis Bambusae In Taenia, property is sweet, is slightly cold, and enters lung, stomach, gallbladder meridian, cures mainly removing heat-phlegm, relieves restlessness and prevents vomiting.For phlegm-heat cough, gallbladder fire is held expectorant under the arm, dysphoria with smothery sensation vomiting, and eye, middle wind-phlegm fan, aphasia with stiff tongue, gastropyretic vomiting, pregnancy reactions, frequent fetal movement are lost in palpitation with fear.This product is good at clearing away phlegm preventing or arresting vomiting, and clearing heat and relieving fidgetness is applicable to phlegm-heat cough, the gastric heat card such as the sound of vomiting, singultus agitation of vomitting, hold concurrently can removing heat from blood antiabortive, and for frequent fetal movement, be the good medicine of controlling simply gastric heat insufficiency of stomach vomiting.
Cortex Cinnamomi, can complement sun, warming the spleen and stomach, removing accumulated cold, promoting blood circulation.Control decline of the fire from the gate of life, cold extremities faint pulse, YANG-depletion collapse, stomachache is had loose bowels, colic of cold type renal mass, chills and pain of the waist and kness, amenorrhea lump in the abdomen, carbuncle of yin nature, multiple abscess, and empty sun is more floating, and heat in the upper and cold in the lower, Cortex Cinnamomi powder warm water takes, and can treat flatulence, cold syndrome of the stomach pain; Cortex Cinnamomi powder is added in dish and cooked, can contribute to control blood glucose and cholesterol.
Fructus Amomi, acrid in the mouth, warm in nature, return spleen channel, stomach warp, kidney channel.Can removing dampness whet the appetite, warming spleen and stopping diarrha, regulate the flow of vital energy antiabortive, be usually used in turbid damp obstructing in middle-JIAO, gastral cavity painful abdominal mass is not hungry, Deficiency and coldness of spleen and stomach, vomiting is had loose bowels, pregnancy reactions, frequent fetal movement.The kind energy of Fructus Amomi warming middle-JIAO warming the stomach is to reach the merit of preventing or arresting vomiting antidiarrheal, but it focuses on warming the spleen.
The Radix Aucklandiae, acrid in the mouth; Bitter; Warm in nature, return spleen; Large intestine, tri-jiao channel.Can circulation of qi promoting, pain relieving, spleen invigorating, helps digestion, and cures mainly promoting the circulation of QI to relieve pain; Intestinal stasis relieving in tune.Main born of the same parents coerce distension foot; Abdominal distention; Tell and have loose bowels; Heavy after dysentery.For heavy after breast gastral cavity distending pain, dysentery, food stagnation does not disappear, anorexia; Middle gas is not economized; Burst is deaf; Snake bite and insect sting; Toothache.In the traditional Chinese medical science as distension and fullness in the abdomen or the pain of stagnation of QI in spleen and stomach, belch, nausea and vomiting medicine.
Fructus Crataegi (parched to brown), is to get clean Fructus Crataegi, fries to surface coke brown inner yellowish-brown according to the method for frying.This product shape is as Fructus Crataegi slice, surface coke brown, inner yellowish-brown.There is burnt odor gas.Sour in the mouth, sweet, tepor, return spleen, stomach, Liver Channel.Can promoting digestion and invigorating the stomach, circulation of qi promoting dissipating blood stasis.For meat stagnation, gastral cavilty distension, dysentery stomachache, blood stasis amenorrhea, postpartum stagnation, trusted subordinate's twinge, hernia pain; Hyperlipemia.The effect of Fructus Crataegi (parched to brown) dyspepsia and intestinal stasis relieving strengthens.For meat stagnation, dysentery is not well.
Fructus Hordei Germinatus (parched), sweet in the mouth, property is flat.Return spleen, stomach warp, demonstrate,prove for rice and flour Rhizoma Dioscoreae dyspepsia.This product can promote the digestion of starchiness food.Can be equal to use with Fructus Crataegi (parched to brown), six songs.Children's's Ruo Zhi breast food is stagnated, alone this product decoction or grind clothes into powder effectively.If control insufficiency of the spleen lack of appetite, food after glutted, can with the Rhizoma Atractylodis Macrocephalae, Pericarpium Citri Reticulatae is equal to use.
Rhizoma Coptidis can heat clearing and damp drying, eliminating fire and detoxication.For damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood is told nosebleed, conjunctival congestion, toothache, quenches one's thirst, carbuncle furuncle; External treatment eczema, eczema, auditory meatus is suppurated.The kind clear part of the body cavity above the diaphragm housing the heart and lungs of Rhizoma Coptidis (processed with wine) is burning hot.For conjunctival congestion, aphtha.Prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice clearing stomach stomach function regulating preventing or arresting vomiting.Tie mutually damp and hot middle resistance, feeling of fullness vomiting for cold and heat.Cornel Rhizoma Coptidis soothing liver-QI stomach function regulating preventing or arresting vomiting.For incoordination between the liver and stomach, vomiting acid regurgitation.The double energy of this product dispersing the stagnated live-QI to relieve the stagnation of QI, for hypochondriac pain, the abdominal pain etc. of irritability stasis or incoordination between the liver and stomach, can be with other Calming liver to disperse Qi decoctions with using.
Semen Coicis, cool in nature, sweet in the mouth, light, is the kernel of grass Semen Coicis.There is spleen invigorating eliminating dampness by diuresis, eliminating impediment antidiarrheal.For effect of edema, beriberi, dysuria, arthralgia chiefly caused by damp pathogen contracture, diarrhea due to hypofunction of the spleen.Function cures mainly: spleen invigorating eliminating dampness by diuresis, eliminating impediment antidiarrheal.For edema, beriberi, dysuria, arthralgia chiefly caused by damp pathogen contracture, diarrhea due to hypofunction of the spleen.
Radix Scutellariae, another name Radix Scutellariae, tsuchikane tea root.For labiate, be used as medicine with root.Have heat clearing and damp drying, removing heat from blood is antiabortive, detoxicating functions.Cure mainly the diseases such as epidemic febrile disease, upper respiratory tract infection, cough due to lung-heat, damp and hot jaundice, pneumonia, dysentery, hemoptysis, conjunctival congestion, frequent fetal movement, hypertension, carbuncle furuncle.The clinical practice of Radix Scutellariae is antibacterial not worse than Rhizoma Coptidis, and does not develop immunity to drugs.
Herba Cistanches, sweet in the mouth, salty, warm in nature.Return kidney, large intestine channel, can kidney-replenishing, benefiting essence-blood, loosening bowel to relieve constipation.For sexual impotence, infertile, soreness of the waist and knees, muscles and bones is unable, dryness of the intestine constipation.
The Pseudobulbus Bletillae (Rhizoma Bletillae), cold in nature, bitter in the mouth, sweet, puckery, nontoxic; Return lung, stomach, Liver Channel.There is astringing to arrest bleeding, the function of detumescence and promoting granulation.Cure mainly slightly blood of pulmonary tuberculosis, spit blood, epistaxis, has blood in stool, traumatic hemorrhage, carbuncle pyogenic infections from tumour or sore, scrofula, anal fistula, burn and scald, rhagadia manus et pedis, the diseases such as anal fissure.With other drug matchings of the present invention, treatment enteritis successful.
Semen setariae, is foxtail millet (Setaria italica) grain of making that shells, because it is little, and diameter 1 millimeter, therefore named.Originate in the north of China Huanghe valley, the staple food crop of ancient Chinese, so Xia dynasty and Shang dynasty belong to " foxtail millet culture ".Foxtail millet growth is drought-enduring, various in style, is commonly called as " foxtail millet has the five colours ", Semen setariae sweet in the mouth cool in nature, can disappear by preventing or arresting vomiting, supports the intestines and stomach, relieving constipation, stopping leak, blood yiqi, spleen invigorating, hypoglycemic and thirst-relieving, yin nourishing tonify deficiency, has good conditioning and tonic effect to gastrointestinal tract: cure mainly dyspepsia: vitamin B group can be secreted by facilitating digestion liquid, maintain and promote and be conducive to defecation by intestinal peristalsis promoting.And effect of the raw skin ulcer of bicker, and nourishing the stomach: in and gastric acid, alleviate stomachache.Semen setariae has the effect that prevents general stomach, vomiting.
From China's Traditional Chinese Medicine angle, the etiology and pathogenesis of chronic enteritis, there is eating and drinking without temperance, kill damaging the spleen and stomach state, or invade in exopathogen, undermine taste, or suffering is disgruntled, the liver failing to maintain the normal flow of QI, perverse and unreasonable manner is violated stomach, and innate deficiency, the situations such as weakness of the spleen and stomach, its sick table is at " intestinal ", but with " stomach ", " spleen ", " liver ", " kidney " is in close relations, pathogenic characteristic is deficiency complicated with excess, therefore the compositions obtaining by the above-mentioned drug matching of the present invention and preparation method, adopt dialectical method effectively to reach effect of conditioning intestinal and the vital organs of the human body, have no side effect, effect stability, reach the curative effect of getting twice the result with half the effort compared with Western medicine.
clinical experiment 1:
1), observing time: in the situation that technical solution of the present invention does not disclose, select 6 months of year August in March, 2012 to 2012.
2), the object of observation: select 10 routine chronic enteritis cases in Guangzhou, Guangdong Gastroenterology dept. of institute of traditional Chinese medicine: male 6 examples, female's 4 examples; Age: 40-55 years old 5 example, 60-75 years old 5 example; Occupation: common working clan's 5 examples, retired person 5 examples.Disease: repeatedly stomachache, the abdominal distention of outbreak, suffer from diarrhoea, rush down lower mucus or bloody purulent stool, stage of attack, defecate more than 3 times/day, companion's defecation is not freely or tenesmus; Tongue fur is how yellow greasy or greasy in vain; All disease is just all made a definite diagnosis through fibercolonscopy.
3), using method: preparation oral liquid of the present invention is being taken after the meal half an hour, and every day 3 times, each 200ml, 2 months was 1 course for the treatment of, and 3 courses for the treatment of are as observation of curative effect.
4), observing effect:
Taking continuously after 3 courses for the treatment of, clinical symptoms, sign disappear, fibro-colonoscope check is normal, and intestinal mucosa pathological changes is recovered normal 6 examples, and clinical symptoms obviously alleviates, sign disappears substantially, fibro-colonoscope check takes a turn for the better, 2 examples that intestinal mucosa pathological changes is obviously improved, and before and after treatment, clinical symptoms and sign are without improvement, fibro-colonoscope check is without 2 examples that take a turn for the better, total effective rate 80%.
clinical experiment 2 :
1), observing time: in the situation that technical solution of the present invention does not disclose, select 6 months of year June in January, 2013 to 2013.
2), the object of observation: 20 routine cases are selected by Gastroenterology dept. of institute of traditional Chinese medicine in Luohu District, Shenzhen City, Guangdong Province: male 12 examples, female's 8 examples; Age: 32-55 years old 10 example, 56-75 years old 10 example; Occupation: post civil servant 10 examples that once assumed the leadership, common teachers 10 examples.Disease: repeatedly stomachache, the abdominal distention of outbreak, suffer from diarrhoea, rush down lower mucus or bloody purulent stool, stage of attack, defecate more than 3 times/day, companion's defecation is not freely or tenesmus; Tongue fur is how yellow greasy or greasy in vain; All disease is just all made a definite diagnosis through fibercolonscopy.
3), using method: preparation oral liquid of the present invention is being taken after the meal half an hour, and every day 3 times, each 200ml, 2 months was 1 course for the treatment of, and 3 courses for the treatment of are as observation of curative effect.
4), observing effect:
Taking continuously after 3 courses for the treatment of, clinical symptoms, sign disappear, fibro-colonoscope check is normal, and intestinal mucosa pathological changes is recovered normal 12 examples, and clinical symptoms obviously alleviates, sign disappears substantially, fibro-colonoscope check takes a turn for the better, 3 examples that intestinal mucosa pathological changes is obviously improved, and before and after treatment, clinical symptoms and sign are without improvement, fibro-colonoscope check is without 5 examples that take a turn for the better, total effective rate 75%.
clinical experiment 3 :
1), observing time: in the situation that technical solution of the present invention does not disclose, select 6 months of in JIUYUE, 2013 to 2014 year February.
2), the object of observation: 30 routine cases are selected by Gastroenterology dept. of hospital in South Mountain, Shenzhen City, Guangdong Province: male 12 examples, female's 18 examples; Age: 35-55 years old 16 example, 60-75 years old 14 example; Occupation: the common master of private enterprise 14 examples, common retired professor's 16 examples.Disease: repeatedly stomachache, the abdominal distention of outbreak, suffer from diarrhoea, rush down lower mucus or bloody purulent stool, stage of attack, defecate more than 3 times/day, companion's defecation is not freely or tenesmus; Tongue fur is how yellow greasy or greasy in vain; All disease is just all made a definite diagnosis through fibercolonscopy.
3), using method: preparation oral liquid of the present invention is being taken after the meal half an hour, and every day 3 times, each 200ml, 2 months was 1 course for the treatment of, and 3 courses for the treatment of are as observation of curative effect.
4), observing effect:
Taking continuously after 3 courses for the treatment of, clinical symptoms, sign disappear, fibro-colonoscope check is normal, and intestinal mucosa pathological changes is recovered normal 18 examples, and clinical symptoms obviously alleviates, sign disappears substantially, fibro-colonoscope check takes a turn for the better, 6 examples that intestinal mucosa pathological changes is obviously improved, and before and after treatment, clinical symptoms and sign are without improvement, fibro-colonoscope check is without 6 examples that take a turn for the better, total effective rate 80%.
In conjunction with above clinical data and theoretical foundation of the present invention, visible beneficial effect of the present invention is, the preparation that the present invention makes has good result for treatment chronic enteritis, and nontoxic, have no side effect, and effect stability, reparation technology is simple and easy to do.
The specific embodiment
Below in conjunction with embodiment, the present invention is explained detailedly:
embodiment 1:
Preparation of the present invention is the composite preparation being prepared into by Herba Pogostemonis, six songs, Semen Lablab Album, Fructus Forsythiae, Poria, Semen Raphani, Radix Bupleuri, Caulis Bambusae In Taenia, Cortex Cinnamomi, Fructus Amomi, the Radix Aucklandiae, Fructus Crataegi (parched to brown), Fructus Hordei Germinatus (parched), Rhizoma Coptidis, Semen Coicis, Radix Scutellariae, Herba Cistanches, the Pseudobulbus Bletillae (Rhizoma Bletillae) and Semen setariae, and wherein the quality proportioning of each component is:
The bent 10g Semen Lablab Album of Herba Pogostemonis 12g six 10g
Fructus Forsythiae 12g Poria 12g Semen Raphani 15g
Radix Bupleuri 10g Caulis Bambusae In Taenia 12g Cortex Cinnamomi 8g
Fructus Amomi 15g Radix Aucklandiae 15g Fructus Crataegi (parched to brown) 13g
Fructus Hordei Germinatus (parched) 12g Rhizoma Coptidis 8g Semen Coicis 10g
Radix Scutellariae 12g Herba Cistanches 13g Pseudobulbus Bletillae (Rhizoma Bletillae) 10g
Semen setariae 16g.
The preparation method of above-mentioned treatment chronic enteritis Chinese medicine oral liquid, comprises the steps:
1), six songs put into pannikin carry out stir-fry dish cooked in a small wok, meaning the food is prepared with special care 2-3 minute, then pulverize and cross 80 mesh sieves through pulverizer, for subsequent use;
2), Herba Pogostemonis, Semen Lablab Album, Fructus Forsythiae, Poria, Radix Bupleuri, Caulis Bambusae In Taenia, Cortex Cinnamomi, Semen setariae, Radix Scutellariae, Herba Cistanches are prepared in proportion, be ground into powder and cross 90 mesh sieves through pulverizer, naturally drying, for subsequent use;
3), by step 1) and 2) in each component powders mix, add pure water to decoct twice, add for the first time the little fire of 8 times of pure water to decoct 1 hour, add for the second time 4 times of little fire of pure water to decoct half an hour, then collecting decoction filtering, for subsequent use;
4), remaining Semen Raphani, Fructus Amomi, the Radix Aucklandiae, Fructus Crataegi (parched to brown), Fructus Hordei Germinatus (parched), Rhizoma Coptidis, Semen Coicis, the Pseudobulbus Bletillae (Rhizoma Bletillae) are prepared in proportion, be ground into powder and cross 80 mesh sieves through pulverizer, naturally drying, for subsequent use;
5), each component powders in step 4) is mixed, add the ethanol of 4～6 times 70%～80%, reflux 3～5 hours, extracts to filter and obtains filtrate; Then in remaining medicinal residues, again add the ethanol of 2～4 times 65%～75%, reflux 2～3 hours, extracts and filters acquisition filtrate; The filtrate of twice acquisition is combined, and concentrating under reduced pressure is removed alcohol solvent, dry, obtains and gets dry extract;
6), by above-mentioned steps 5) in obtain dry cream carry out micronizing powdered and cross 200 mesh sieves, then powder is added to the collecting decoction in step 3), mix shake up and can make.
The above-mentioned Chinese medicine composition pharmaceutical solutions of producing can be for oral, if can respectively drink once and long-term drink better effects if the morning, noon and afternoon.
embodiment 2:
The present invention also preferably raw materials quality be (gram):
The bent 10g Semen Lablab Album of Herba Pogostemonis 12g six 10g
Fructus Forsythiae 12g Poria 12g Semen Raphani 15g
Radix Bupleuri 10g Caulis Bambusae In Taenia 12g Cortex Cinnamomi 8g
Fructus Amomi 15g Radix Aucklandiae 10g Fructus Crataegi (parched to brown) 13g
Fructus Hordei Germinatus (parched) 12g Rhizoma Coptidis 8g Semen Coicis 10g
Radix Scutellariae 12g Herba Cistanches 13g Pseudobulbus Bletillae (Rhizoma Bletillae) 10g
Semen setariae 16g.
Preparation method is as embodiment 1.
embodiment 3:
The present invention also preferably raw materials quality be (gram):
The bent 12g Semen Lablab Album of Herba Pogostemonis 15g six 9g
Fructus Forsythiae 15g Poria 10g Semen Raphani 12g
Radix Bupleuri 12g Caulis Bambusae In Taenia 10g Cortex Cinnamomi 8g
Fructus Amomi 12g Radix Aucklandiae 14g Fructus Crataegi (parched to brown) 12g
Fructus Hordei Germinatus (parched) 8g Rhizoma Coptidis 8g Semen Coicis 12g
Radix Scutellariae 10g Herba Cistanches 8g Pseudobulbus Bletillae (Rhizoma Bletillae) 10g
Semen setariae 15g.
Preparation method is as embodiment 1.
embodiment 4:
The present invention also preferably raw materials quality be (gram):
The bent 15g Semen Lablab Album of Herba Pogostemonis 18g six 12g
Fructus Forsythiae 16g Poria 12g Semen Raphani 15g
Radix Bupleuri 13g Caulis Bambusae In Taenia 15g Cortex Cinnamomi 12g
Fructus Amomi 16g Radix Aucklandiae 14g Fructus Crataegi (parched to brown) 16g
Fructus Hordei Germinatus (parched) 10g Rhizoma Coptidis 12g Semen Coicis 15g
Radix Scutellariae 16g Herba Cistanches 13g Pseudobulbus Bletillae (Rhizoma Bletillae) 12g
Semen setariae 18g.
Preparation method is as embodiment 1.
embodiment 5 :
The present invention also preferably raw materials quality be (gram):
The bent 18g Semen Lablab Album of Herba Pogostemonis 16g six 15g
Fructus Forsythiae 14g Poria 15g Semen Raphani 18g
Radix Bupleuri 15g Caulis Bambusae In Taenia 18g Cortex Cinnamomi 14g
Fructus Amomi 18g Radix Aucklandiae 16g Fructus Crataegi (parched to brown) 14g
Fructus Hordei Germinatus (parched) 12g Rhizoma Coptidis 13g Semen Coicis 13g
Radix Scutellariae 18g Herba Cistanches 15g Pseudobulbus Bletillae (Rhizoma Bletillae) 15g
Semen setariae 18g.
Preparation method is as embodiment 1.
embodiment 6 :
The present invention also preferably raw materials quality be (gram):
The bent 18g Semen Lablab Album of Herba Pogostemonis 15g six 15g
Fructus Forsythiae 16g Poria 15g Semen Raphani 20g
Radix Bupleuri 12g Caulis Bambusae In Taenia 20g Cortex Cinnamomi 16g
Fructus Amomi 16g Radix Aucklandiae 18g Fructus Crataegi (parched to brown) 15g
Fructus Hordei Germinatus (parched) 15g Rhizoma Coptidis 15g Semen Coicis 12g
Radix Scutellariae 16g Herba Cistanches 16g Pseudobulbus Bletillae (Rhizoma Bletillae) 13g
Semen setariae 20g.
Preparation method is as embodiment 1.
Above-described embodiment is only the several of the numerous embodiments of the present invention, and as each formula strengthened in the ratio in technical scheme or reducing dose, this treatment chronic enteritis preparation curative effect making is also unaffected, within also will dropping on the scope of the present invention.
Claims (4)
1. treat the Chinese medicine oral liquid of chronic enteritis for one kind, it is characterized in that, preparation of the present invention is the composite preparation being prepared into by Herba Pogostemonis, six songs, Semen Lablab Album, Fructus Forsythiae, Poria, Semen Raphani, Radix Bupleuri, Caulis Bambusae In Taenia, Cortex Cinnamomi, Fructus Amomi, the Radix Aucklandiae, Fructus Crataegi (parched to brown), Fructus Hordei Germinatus (parched), Rhizoma Coptidis, Semen Coicis, Radix Scutellariae, Herba Cistanches, the Pseudobulbus Bletillae (Rhizoma Bletillae) and Semen setariae, and wherein the quality proportioning of each component is:
The bent 10-22g Semen Lablab Album of Herba Pogostemonis 12-20g six 8-18g
Fructus Forsythiae 10-18g Poria 8-15g Semen Raphani 10-20g
Radix Bupleuri 8-16g Caulis Bambusae In Taenia 12-20g Cortex Cinnamomi 8-16g
Fructus Amomi 10-18g Radix Aucklandiae 10-18g Fructus Crataegi (parched to brown) 10-18g
Fructus Hordei Germinatus (parched) 8-15g Rhizoma Coptidis 6-15g Semen Coicis 8-15g
Radix Scutellariae 10-18g Herba Cistanches 8-16g Pseudobulbus Bletillae (Rhizoma Bletillae) 8-15g
Semen setariae 10-20g.
2. the Chinese medicine oral liquid for the treatment of chronic enteritis according to claim 1, is further characterized in that, wherein the quality proportioning of each component is:
The bent 10-18g Semen Lablab Album of Herba Pogostemonis 12-18g six 8-12g
Fructus Forsythiae 12-18g Poria 8-12g Semen Raphani 10-15g
Radix Bupleuri 8-12g Caulis Bambusae In Taenia 12-16g Cortex Cinnamomi 8-12g
Fructus Amomi 10-15g Radix Aucklandiae 10-14g Fructus Crataegi (parched to brown) 10-15g
Fructus Hordei Germinatus (parched) 8-12g Rhizoma Coptidis 6-10g Semen Coicis 8-12g
Radix Scutellariae 10-15g Herba Cistanches 8-12g Pseudobulbus Bletillae (Rhizoma Bletillae) 8-12g
Semen setariae 12-18g.
3. the Chinese medicine oral liquid for the treatment of chronic enteritis according to claim 1 and 2, is further characterized in that, wherein the quality proportioning of each component is:
The bent 12g Semen Lablab Album of Herba Pogostemonis 15g six 9g
Fructus Forsythiae 15g Poria 10g Semen Raphani 12g
Radix Bupleuri 12g Caulis Bambusae In Taenia 10g Cortex Cinnamomi 8g
Fructus Amomi 12g Radix Aucklandiae 14g Fructus Crataegi (parched to brown) 12g
Fructus Hordei Germinatus (parched) 8g Rhizoma Coptidis 8g Semen Coicis 12g
Radix Scutellariae 10g Herba Cistanches 8g Pseudobulbus Bletillae (Rhizoma Bletillae) 10g
Semen setariae 15g.
4. a preparation method for the treatment of the Chinese medicine oral liquid of chronic enteritis, is characterized in that, it comprises the steps:
1), six songs put into pannikin carry out stir-fry dish cooked in a small wok, meaning the food is prepared with special care 2-3 minute, then pulverize and cross 80 mesh sieves through pulverizer, for subsequent use;
2), Herba Pogostemonis, Semen Lablab Album, Fructus Forsythiae, Poria, Radix Bupleuri, Caulis Bambusae In Taenia, Cortex Cinnamomi, Semen setariae, Radix Scutellariae, Herba Cistanches are prepared in proportion, be ground into powder and cross 90 mesh sieves through pulverizer, naturally drying, for subsequent use;
3), by step 1) and 2) in each component powders mix, add pure water to decoct twice, add for the first time the little fire of 10 times of pure water to decoct 1 hour, extract filtrate for later use, add for the second time 6 times of little fire of pure water to decoct half an hour, then collecting decoction filtration, for subsequent use;
4), remaining Semen Raphani, Fructus Amomi, the Radix Aucklandiae, Fructus Crataegi (parched to brown), Fructus Hordei Germinatus (parched), Rhizoma Coptidis, Semen Coicis, the Pseudobulbus Bletillae (Rhizoma Bletillae) are prepared in proportion, be ground into powder and cross 80 mesh sieves through pulverizer, naturally drying, for subsequent use;
5), each component powders in step 4) is mixed, add the ethanol of 4～6 times 70%～80%, reflux 3～5 hours, extracts to filter and obtains filtrate; Then in remaining medicinal residues, again add the ethanol of 2～4 times 65%～75%, reflux 2～3 hours, extracts and filters acquisition filtrate; The filtrate of twice acquisition is combined, and concentrating under reduced pressure is removed alcohol solvent, dry, obtains and gets dry extract;
6), by above-mentioned steps 5) in obtain dry cream carry out micronizing powdered and cross 200 mesh sieves, then powder is added to the collecting decoction in step 3), mix and shake up and can make, the above-mentioned Chinese medicine composition pharmaceutical solutions of producing can be for oral, if can each also long-term drink, better effects if of drinking in right amount once of morning, noon and afternoon.
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