CN103875973B - A kind of laying cycle of laying hens feed addictive and preparation method thereof - Google Patents
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Abstract
The invention discloses a kind of laying cycle of laying hens feed addictive and preparation method thereof, described feed addictive comprises Chinese medicine additive, enzymatic compositions and vitamine D3, wherein, the ratio of weight and number of Chinese medicine additive, enzymatic compositions and vitamine D3 is 1:1:0.01-0.5; Chinese medicine additive comprises following raw medicinal material: marine alga, rhizoma atractylodis, Radix Codonopsis, caryophyllaceous ginseng, chrysanthemum, comfrey, pollen, Chinese scholartree leaf, the membrane of a chicken's gizzard, trifoliate orange, fructus amomi, Chinese yam, French beans, date, thizoma curculiginis, matrimony vine, walnut kernel, the seed of Chinese dodder, glutinous rice rhizome and root and maidenhair.The invention has the beneficial effects as follows: feed addictive of the present invention contains Chinese medicine additive, there is effect of invigorating the spleen to dry, invigorating the kidney and spleen, with other raw material matcheds, the cholesterol level of laying hen egg can not only be reduced, improve laying rate and the egg size of laying hen, but also the resistance against diseases of laying hen can be improved.
Description
Technical field
The present invention relates to the animal-breeding feed additive containing deriving from plant, animal or raw mineral materials, particularly a kind of laying cycle of laying hens feed addictive and preparation method thereof.
Background technology
Egg is chosen as " breakfast of most nutrition in the world " by a certain magazine of the U.S..According to this section of magazine ran, egg is not only containing the multiple nutrients material that people know, and it is also containing two seed amino acids---tryptophan and tyrosine, and these two kinds of acid can help human body anti-oxidant.
Egg is one of best source of nutrition of the mankind, containing a large amount of vitamin and mineral matter and the protein having high biological value in egg.For people, the protein quality of egg is best, is only second to breast milk.Heat contained by an egg, be equivalent to the heat of half apple or half cup milk, but it also has the phosphorus of 8%, zinc, the iron of 4%, protein, the vitamin D of 6%, vitamin E, the vitamin A of 6%, Cobastab, the vitamin B2 of 5%, the vitamin B6 of 4% of 2% of 3% of 12. 6% of 4%.These nutrition are all that human body is requisite, and they play an important role, as repaired tissue, forming the metabolic processes etc. of new tissue, consumed energy and participation complexity.
Containing more cholesterol in egg yolk, every hectogram can up to 1510 milligrams, and therefore, Bu Shaoren, particularly the elderly keep a sharp lookout to eating egg, are afraid of that eating egg causes cholesterol increase and cause atherosclerotic.Scientists study finds, though containing more cholesterol in egg, simultaneously also containing abundant lecithin.After lecithin enters blood, the particle of cholesterol and fat can be made to diminish, and make it to keep suspended state, thus stop cholesterol and the deposition of fat at vascular wall.Cholesterol is the important component of cell membrane, and it is necessary to be that the mankind maintain normal physiological activity, but in blood of human body, the too high meeting of cholesterol concentration causes high fat of blood, and then causes a series of angiocardiopathy such as hypertension, coronary heart disease.Egg is the nutraceutical that people generally acknowledge, is the one that in animal food, cholesterol level is higher, average 213mg/ piece.American Heart research association recommends human body cholesterol intake every day should more than 300mg, to reduce the danger of high fat of blood and coronary heart disease.Along with the enhancing of people's health care consciousness, people wish the food taking in high cholesterol count less, thus, reduce Egg cholesterol amount and have important theoretical and practical significance.
A cholesterol part in laying hen body is directly entered in intestines through biliary system by liver, and becomes stercorin by enteric bacteria effect and excrete with ight soil; A part forms cyto-architectural composition in tissue; Most cholesterol proceeds in yolk, excretes with the form of laying eggs.Egg cholesterol is almost all present in yolk, and every gram of yolk is on average containing cholesterol 13mg.Yolk moisture content about 50%, all the other major parts are protein and fat, the ratio of protein and fat is about 1:2, fat mainly exists with lipoprotein form, as VLDL (VLDL) and lipovitellin, phosvitin etc., the cholesterol of more than 95% exists with VLDL form.Laying hen about synthesizes the cholesterol of 300mg every day, wherein about has 200mg to be deposited in yolk; 10mg cholesterol directly enters enteron aisle, excretes with ight soil.Yolk cholesterol is mainly derived from precursor-VLDL (VLDL) and vitellogenin (VTG) quantity of liver synthesis yolk, and cholesterol level of vitellus depends primarily on the quantity that VLDL enters egg mother cell.After in blood, VLDL arrives the egg mother cell of ovary, the egg mother cell in the encytosis of receptor-mediated (OVR) is grown absorbs, and forms the dry of yolk 95% cholesterol and 60% thus.Meanwhile, vitellogenin arrives egg mother cell with same approach in post synthesis, provides the dry of 4% cholesterol and 24% to yolk.
Raiser, in order to pursue market interest, widely applies the chemical synthetic drugs such as antibiotic, although can reduce the content of egg cholesterol, also seriously reduce the quality of egg, higher drug residue affects the healthy of consumer simultaneously.
Summary of the invention
In order to realize the cholesterol level reducing laying hen egg, improving egg production and egg size, improving the object of the immunity of laying hen simultaneously, embodiments provide a kind of laying cycle of laying hens feed addictive and preparation method thereof.
In order to realize foregoing invention object, the invention provides a kind of laying cycle of laying hens feed addictive, described feed addictive comprises Chinese medicine additive, enzymatic compositions and vitamine D3, and wherein, the ratio of weight and number of described Chinese medicine additive, enzymatic compositions and vitamine D3 is 1:1:0.01-0.5; Described Chinese medicine additive comprises following raw medicinal material: marine alga, rhizoma atractylodis, Radix Codonopsis, caryophyllaceous ginseng, chrysanthemum, comfrey, pollen, Chinese scholartree leaf, the membrane of a chicken's gizzard, trifoliate orange, fructus amomi, Chinese yam, French beans, date, thizoma curculiginis, matrimony vine, walnut kernel, the seed of Chinese dodder, glutinous rice rhizome and root and maidenhair.
Described enzymatic compositions is one or more in zytase, 1,4 beta-glucanase, 'beta '-mannase, cellulase, amylase or protease; Described enzymatic compositions is preferably zytase, 1,4 beta-glucanase, 'beta '-mannase, cellulase, amylase and protease, and its ratio of weight and number is: 1:1:2:1:2:1.
In described Chinese medicine additive, the parts by weight of each raw medicinal material are preferably: marine alga 15-25 weight portion, rhizoma atractylodis 10-20 weight portion, Radix Codonopsis 15-25 weight portion, caryophyllaceous ginseng 10-15 weight portion, chrysanthemum 13-24 weight portion, comfrey 10-20 weight portion, pollen 10-20 weight portion, Chinese scholartree leaf 15-25 weight portion, the membrane of a chicken's gizzard 15-25 weight portion, trifoliate orange 10-18 weight portion, fructus amomi 10-16 weight portion, Chinese yam 10-20 weight portion, French beans 10-20 weight portion, date 10-20 weight portion, thizoma curculiginis 10-20 weight portion, matrimony vine 15-25 weight portion, walnut kernel 10-20 weight portion, seed of Chinese dodder 10-20 weight portion, glutinous rice rhizome and root 10-20 weight portion and maidenhair 10-15 weight portion.
In described Chinese medicine additive, the parts by weight of each raw medicinal material can also be preferably: marine alga 18 weight portion, rhizoma atractylodis 17 weight portion, Radix Codonopsis 19 weight portion, caryophyllaceous ginseng 13 weight portion, chrysanthemum 20 weight portion, comfrey 16 weight portion, pollen 15 weight portion, Chinese scholartree leaf 20 weight portion, the membrane of a chicken's gizzard 19 weight portion, trifoliate orange 14 weight portion, fructus amomi 13 weight portion, Chinese yam 15 weight portion, French beans 15 weight portion, date 17 weight portion, thizoma curculiginis 17 weight portion, matrimony vine 21 weight portion, walnut kernel 15 weight portion, the seed of Chinese dodder 15 weight portion, glutinous rice rhizome and root 15 weight portion and maidenhair 13 weight portion.
Described Chinese medicine additive also comprises: glossy ganoderma, barley, lotus leaf, dried orange peel and paniculate swallowwort.
In described Chinese medicine additive, the parts by weight of each raw medicinal material are preferably: marine alga 15-25 weight portion, rhizoma atractylodis 10-20 weight portion, Radix Codonopsis 15-25 weight portion, caryophyllaceous ginseng 10-15 weight portion, chrysanthemum 13-24 weight portion, comfrey 10-20 weight portion, pollen 10-20 weight portion, Chinese scholartree leaf 15-25 weight portion, the membrane of a chicken's gizzard 15-25 weight portion, trifoliate orange 10-18 weight portion, fructus amomi 10-16 weight portion, Chinese yam 10-20 weight portion, French beans 10-20 weight portion, date 10-20 weight portion, thizoma curculiginis 10-20 weight portion, matrimony vine 15-25 weight portion, walnut kernel 10-20 weight portion, seed of Chinese dodder 10-20 weight portion, glutinous rice rhizome and root 10-20 weight portion, maidenhair 10-15 weight portion, glossy ganoderma 15-25 weight portion, barley 10-18 weight portion, lotus leaf 10-15 weight portion, dried orange peel 10-20 weight portion and paniculate swallowwort 10-15 weight portion.
In described Chinese medicine additive, the parts by weight of each raw medicinal material can also be preferably: marine alga 21 weight portion, rhizoma atractylodis 15 weight portion, Radix Codonopsis 20 weight portion, caryophyllaceous ginseng 12 weight portion, chrysanthemum 16 weight portion, comfrey 15 weight portion, pollen 15 weight portion, Chinese scholartree leaf 18 weight portion, the membrane of a chicken's gizzard 22 weight portion, trifoliate orange 14 weight portion, fructus amomi 13 weight portion, Chinese yam 15 weight portion, French beans 15 weight portion, date 15 weight portion, thizoma curculiginis 15 weight portion, matrimony vine 19 weight portion, walnut kernel 15 weight portion, the seed of Chinese dodder 15 weight portion, glutinous rice rhizome and root 15 weight portion, maidenhair 12 weight portion, glossy ganoderma 20 weight portion, barley 14 weight portion, lotus leaf 13 weight portion, dried orange peel 15 weight portion and paniculate swallowwort 13 weight portion.
In order to better realize foregoing invention object, the invention provides a kind of preparation method of laying cycle of laying hens feed addictive, described preparation method comprises the following steps:
The first step, mixes by ratio of weight and the number of copies by above-mentioned various raw medicinal material, drops into pulverizer and carries out pulverizing or directly shredding, load and decoct in container, add suitable quantity of water and make its submergence medicinal material, soak after 30-60 minute, be heated to boiling after 30-60 minute, be separated fried liquid, the dregs of a decoction again add water and carry out decoction 2-3 time, isolate fried liquid respectively at every turn, merge all fried liquid, again after filtering, get filtrate and abandon filter residue;
Second step, after liquid cooling but to be filtered, adding relative to concentrated rear liquid weight 1-2 determining alcohol is doubly 80-90% ethanol, fully mix, placement is spent the night, and makes it precipitate, obtain filtrate after getting its supernatant liquid filtering next day, sediment determining alcohol is that the ethanol of 50-60% is cleaned, and collects washing lotion and merges with filtrate, after ethanol is regained in decompression, leave standstill 0.5-1 hour, make precipitation complete, filter, filtrate low-temperature evaporation, obtains paste;
3rd step: paste is put into spray dryer dry, ensure that EAT is at 180 DEG C-200 DEG C, leaving air temp 70 DEG C-90 DEG C, is ground into 200 order-300 orders subsequently, obtains Chinese medicine additive pulvis;
4th step: by weight Chinese medicine additive, enzymatic compositions and vitamine D3 mixed and obtain feed addictive.
Present invention also offers a kind of laying cycle of laying hens Chinese medicine additive, described Chinese medicine additive is made up of the raw medicinal material of following parts by weight: marine alga 15-25 weight portion, rhizoma atractylodis 10-20 weight portion, Radix Codonopsis 15-25 weight portion, caryophyllaceous ginseng 10-15 weight portion, chrysanthemum 13-24 weight portion, comfrey 10-20 weight portion, pollen 10-20 weight portion, Chinese scholartree leaf 15-25 weight portion, the membrane of a chicken's gizzard 15-25 weight portion, trifoliate orange 10-18 weight portion, fructus amomi 10-16 weight portion, Chinese yam 10-20 weight portion, French beans 10-20 weight portion, date 10-20 weight portion, thizoma curculiginis 10-20 weight portion, matrimony vine 15-25 weight portion, walnut kernel 10-20 weight portion, seed of Chinese dodder 10-20 weight portion, glutinous rice rhizome and root 10-20 weight portion, maidenhair 10-15 weight portion, glossy ganoderma 15-25 weight portion, barley 10-18 weight portion, lotus leaf 10-15 weight portion, dried orange peel 10-20 weight portion and paniculate swallowwort 10-15 weight portion.
In order to better realize foregoing invention object, the invention provides a kind of preparation method of laying cycle of laying hens feed addictive, described preparation method comprises the following steps:
The first step, mixes by ratio of weight and the number of copies by various raw medicinal material, drops into pulverizer and carries out pulverizing or directly shredding, load and decoct in container, add suitable quantity of water and make its submergence medicinal material, soak after 30-60 minute, be heated to boiling after 30-60 minute, be separated fried liquid, the dregs of a decoction again add water and carry out decoction 2-3 time, isolate fried liquid respectively at every turn, merge all fried liquid, again after filtering, get filtrate and abandon filter residue;
Second step, after liquid cooling but to be filtered, adding relative to concentrated rear liquid weight 1-2 determining alcohol is doubly 80-90% ethanol, fully mix, placement is spent the night, and makes it precipitate, obtain filtrate after getting its supernatant liquid filtering next day, sediment determining alcohol is that the ethanol of 50-60% is cleaned, and collects washing lotion and merges with filtrate, after ethanol is regained in decompression, leave standstill 0.5-1 hour, make precipitation complete, filter, filtrate low-temperature evaporation, obtains paste;
3rd step: paste is put into spray dryer dry, ensure that EAT is at 180 DEG C-200 DEG C, leaving air temp 70 DEG C-90 DEG C, is ground into 200 order-300 orders subsequently, obtains Chinese medicine additive pulvis.
The beneficial effect that the technical scheme that the embodiment of the present invention provides is brought is: feed addictive of the present invention contains Chinese medicine additive, there is effect of invigorating the spleen to dry, invigorating the kidney and spleen, with other raw material matcheds, the cholesterol level of laying hen egg can not only be reduced, improve laying rate and the egg size of laying hen, but also the resistance against diseases of laying hen can be improved.
Detailed description of the invention
The invention provides a kind of feed addictive containing Chinese medicine additive, wherein Chinese medicine additive comprises following raw medicinal material: marine alga, rhizoma atractylodis, Radix Codonopsis, caryophyllaceous ginseng, chrysanthemum, comfrey, pollen, Chinese scholartree leaf, the membrane of a chicken's gizzard, trifoliate orange, fructus amomi, Chinese yam, French beans, date, thizoma curculiginis, matrimony vine, walnut kernel, the seed of Chinese dodder, glutinous rice rhizome and root and maidenhair; Preferably, Chinese medicine additive also comprises: glossy ganoderma, barley, lotus leaf, dried orange peel and paniculate swallowwort.
In Chinese herb feed additive, the pharmacology of each raw medicinal material is as follows:
Marine alga: bitter, salty, cold in nature, nontoxic.Gui Jing: lung; Spleen; Kidney; Liver stomach is through effect: soft heavily fortified point; Dissolving phlegm; Li Shui; Detumescence.Thyroid Gland Swell, item inferior gluteal lymph node tuberculosis.Dissipating bind gas carbuncle swells, and abdomen inner product block, distending pain, abdomen hollow are rung.Also can descend 12 kinds of oedema, treat between skin and gather sudden and violent bursting, stay depressed heat, diuresis.Cure mainly: scrofula; Goiter and tumor; Gather; Oedema; Beriberi; Testiclar gall; (Epileptic is ruined) hernia." Haiyao Bencao, Oversea Materia Medica " records it: " main place food does not disappear, and five phlegm of separating are stopped up, aqueous vapor edema, beriberi, up-rushing gas syndrome ".Marine alga contains a kind of special protein and is called close glycoprotein, and it has compatibility to certain sugars and Non-covalent binding with it.Can cause cell settlement phenomenon after parent's glycoprotein and cell membrane glycan molecule combine, be therefore a kind of agglutinin.Parent's glycoprotein is prevalent in land animals and plants and microorganism, especially enriches especially in seeds of leguminous plant.The characteristic of its identification carbohydrate of parent's glycoprotein mat, the defence of biology, growth, reproduction, nutrition storage and biocenosis are played an important role.Parent's glycoprotein also can be applicable to blood cell and is separated and detects, on the generation of pharmaceutical carrier, immune antiboidy and the medical usage of cancer therapy drug.
Rhizoma atractylodis: nature and flavor are pungent, bitter, temperature.Return spleen, stomach, Liver Channel.Cure mainly: the transporting imbalance that the spleen being blocked by dampness causes, poor appetite, vomiting is unhappy, and abdominal distension is had loose bowels, arthralgia.For dampness taste, abdominal fullness and distention, cold-dampness leukorrhea, damp-warm diseases and damp invasion of lower energizer, pin swelling and pain in knee, impotence are soft unable.Control dampness taste, and see the thick disease such as turbid of abdominal fullness and distention, poor appetite, lassitude hypodynamia, white and greasy fur, the normal and compatibility such as the bark of official magnolia, dried orange peel is applied; Controlling cold-dampness leukorrhea, the root of Dahurain angelica can being joined with using.As damp and hot leukorrhea, the wind-weed, kuh-seng, Patrinia heterophylla can be joined again; Damp invasion of lower energizer, pin swelling and pain in knee, impotence are soft unable, can join golden cypress, the root of bidentate achyranthes, the equivalent use of coix seed; Damp-warm syndrome disease can join the equivalent use of gypsum.Rhizoma atractylodis have drying damp and strengthening spleen, effect of wines used as antirheumatic.Cure mainly damp retention in middle-jiao, wind-cold-dampness arthralgia, pin swelling and pain in knee, impotence is soft unable, night blindness yctalopia." pearl sac " day: " stomach invigorating can pacify spleen, all wet swollen non-these can not remove." Compendium of Material Medica says: " control wet phlegm and stay drink ... and spleen wets dirty, under turbid drop band, slide and rush down intestines wind." " Tang materia medica " claim it can " diuresis ".
Radix Codonopsis: Codonopsis plant.The whole world about has 40 kinds, and China about has 39 kinds, and medicinal have 21 kinds, 4 mutation.Chinese medicine Radix Codonopsis is Campanulaceae herbaceos perennial Radix Codonopsis, the plain root spent Radix Codonopsis, radix codonpsis tangshen and belong to various plants together.Radix Codonopsis is traditional tonic that China commonly uses, and the Radix Codonopsis that ancient times produce with area, Shangdang, Shanxi is top grade, has tonifying middle-Jiao and Qi, effect of invigorating the spleen benefit lung.Modern study, Radix Codonopsis, containing various saccharides, phenols, sterol, volatile oil, scutellarein glucosid, saponin and Alkaloid, has develop immunitypty, hemangiectasis, step-down, improves microcirculation, strengthens the effects such as hematopoiesis function.In addition the leucocyte caused chemotherapy radiotherapy declines and has castering action.Radix Codonopsis has tonifying middle-Jiao and Qi, effect of invigorating the spleen benefit lung.Weak for the spleen deficiency syndrome of the lung, palpitaition of breathing hard, anorexia and loose stool, void is breathed with cough and is coughed, and interior heat is quenched one's thirst." new compilation of materia medica " is recorded: " tonifying middle-Jiao and Qi and taste, relieving thirst and restlessness.Middle gas is faint, mends in order to adjust, very smooth and proper." impact on digestive system: adjustment gastrointestinal motility function Radix Codonopsis is the key medicine of tonifying middle-Jiao and Qi, can correct the gastrointestinal motility dysfunction of pathological state.By the method for chronic heeling-in stomach electrode, observing Radix Codonopsis water decoction-alcohol sedimentation liquid has regulating action to rat stomach basic electric rhythm disorder under stress situation, can partly increase and rapid gastric emptying the stomach motion that resisting stress causes.Asiabell preparation intravenous injection is wriggled to normal rat stomach or is all had inhibitory action with the peristole that neostigmine enhances, and shows as the reduction of peristaltic wave amplitude, frequency deceleration.Radix Codonopsis decocting liquid can improve mouse III degree and scald hindgut power function obstacle, significantly improves Intestinal propulsive rate.Radix Codonopsis liquid has suppression and excited two kinds of effects to isolated guinea pig ileum, tensile force of ileum can be made to raise or first fall rear liter, Frequency downshift, and can maintain the long period, cause ileum contraction to have obvious antagonism to acetylcholine and 5-HT.Antiulcer action Radix Codonopsis water decoction-alcohol sedimentation liquid is to all having preventive and therapeutic action by Experimental Gastric Ucler caused by type, pyloric ligation ulcers, indocin or aspirin.Compare through experiment, with the neutral extract of the just alcohol of Radix Codonopsis to the good effect of stress ulcer, ulcer inhibition rate can reach 98 %, it is 72.9% that water extract takes second place, and ligroin extraction effect is the poorest.Radix Codonopsis water soluble part VII extract can resist and be damaged and gastric ulcer by the caused gastric mucosa such as absolute ethyl alcohol, strong acid (0.6NHCI) and highly basic (0.2NNaOH).Radix Codonopsis has inhibitory action to rat basal gastric acid secretion, pepsin activity can be reduced, and resist aspirin caused hydrochloric acid in gastric juice and increase, declining to indocin, aspirin caused gastric mucosa PGE2 (PGE2) and amidohexose content also has inhibitory action.
Caryophyllaceous ginseng: sweetness and bitterness is put down, and enters spleen, lung channel.Function: nourishing generate fluid.For impairment of both QI and YIN after being ill, spontaneous perspiration of losing heart, poor appetite, thirsty, the diseases such as deficiency of Yin cough caused by dryness.
Chrysanthemum: cold nature, bitter, pungent." book on Chinese herbal medicine converges and says ": " broken blood is soothing the liver, separates the loose poison of malignant boil.Place blood in housewife people's abdomen, the malicious red malignant boil of the capable fire of Xie Tian.Wash sore scabies, wind desinsection can be removed again." function is clearing heat and detoxicating, detumescence.To staphylococcus aureus, corynebacterium diphtheriae, streptococcus, Pseudomonas aeruginosa, puncture Shigella, influenza virus, all there is inhibitory action.To furunculosis, ulcer, erysipelas, eczema, dermatitis, anemopyretic cold, abscess of throat, high blood pressure etc. have good curative effect.
Comfrey: comfrey is the animal and fowl fodder plant of good quality and high output, once plantation can utilize more than 20 year continuously.Through and clover, silphium perfoliatum L etc. more than 20 plant herbage and plant and feed and compare, comfrey has three unique large economic traits, and one is that grass yield is high, and power of regeneration is strong.Spring, summer, Qiu Sanji can with cutting with length, and a Growing season north can cradle 3 times ~ 4 times, and south can cradle 4 times ~ 6 times.Generally every batch of mu green forage yield 0.4 ten thousand kilograms ~ 0.5 ten thousand kilograms, is the high quality forage kind of high yield in Chinese all kinds of herbage.Two is good palatabilities, and digestibility is high.The blue or green tender succulence of comfrey branches and leaves, fragrant odour, quality is soft.Green grass gives out light cucumber fragrance, pig, ox, sheep, rabbit, chicken, duck, goose, ostrich, the equal eating of phytophage fish after chopping or making beating, and can significantly promote to store growing of fowl.Comfrey is rich in protein and vitamin, is of high nutritive value, and the content of various nutritional labeling and digestibility thereof are all higher than general herbage.Through inspection, containing thick protein 24.3% in comfrey fresh careless dry in florescence, crude fat 5.9%, crude fibre 10.1%.In addition, it is also containing a large amount of allantoins and vitamin B12, can prevention and therapy domestic animal and fowl's enteritis, does not have loose bowels after livestock food.
Pollen: be rich in several amino acids, protein, vitamin and bioactivator, can dispel various pigment spot again, has adjustment nervous system, promotes sleep, builds up health; Improve functions of intestines and stomach, promote digestion, whet the appetite, effect of control habitual constipation.Effect of zasiokaurin: cholagogic detumescence, removing jaundice, sharp blood, diuresis, hypotensive, and human body renal function is strengthened the body resistance to consolidate the constitution suitable curative effect.Can prophylactic treatment nephritic dropsy, renal shutdown, cholecystitis, gall stone, jaundice type hepatitis, hypotensive, hypertrophy of the prostate, prostatitis, specially control andropathy.
Chinese scholartree leaf: control frightened epilepsy, high fever, intestines wind, haematuria, hemorrhoid, mange, eczema, malignant boil swells.There is antiinflammatory action, antivirus action.
The membrane of a chicken's gizzard: taste is sweet, cold in nature, enter spleen, stomach, small intestine, urinary bladder channel, the effect having reinforcing spleen to promote digestion, puckery essence only to drown, is mainly used in the abdominal fullness and distention of dyspepsia stagnation, and heating installation is suffered from diarrhoea, the symptoms such as infant malnutrition, the membrane of a chicken's gizzard can promote gastric secretion, strengthens peristole, accelerate the effects such as gastric emptying.
Trifoliate orange: taste is sweet, cold in nature, enter spleen, stomach, small intestine, urinary bladder channel, the effect having reinforcing spleen to promote digestion, puckery essence only to drown, is mainly used in the abdominal fullness and distention of dyspepsia stagnation, and heating installation is suffered from diarrhoea, the symptoms such as infant malnutrition, the membrane of a chicken's gizzard can promote gastric secretion, strengthens peristole, accelerate the effects such as gastric emptying.
Fructus amomi: be Perenniporia martius zingiberaceous plant fruits and seeds, be the conventional medicinal material of armaticity simply of the traditional Chinese medical science.The Ji Yuan of fructus amomi medicinal at present mainly contains three kinds: a kind of is the spring sand mainly originating in Chinese Guangdong province; A kind of is the shell sand in Chinese Hainan; Also have one to be Amomum xanthioides, main product is in country in Southeast Asia.Wherein, the comparitive study that spring sand (fruit) is used as medicine is remarkable, and quality is also relatively good, and higher reputation is enjoyed in international medicinal material market.The traditional Chinese medical science is thought, fructus amomi mainly acts on the stomach of human body, kidney and spleen, can promoting the circulation of qi seasoning, and stomach is amusing.
Chinese yam: tonifying spleen nourishing the stomach, promote the production of body fluid beneficial lung, the puckery essence of kidney tonifying.Few for insufficiency of the spleen food, endless diarrhea, the deficiency syndrome of the lung is breathed with cough, emission due to the kidney deficiency, and under band, frequent micturition, abnormal heat is quenched one's thirst.Rhizoma Dioscoreae (parched with bran) tonifying spleen stomach invigorating.Few for insufficiency of the spleen food, loose stool of having loose bowels, leukorrhea.This product yin-nourishing can help wet, in containing so wet full or have stagnant, have real evil person unsuitable.Need to remind everybody, edible Chinese yam generally without obvious contraindication, but has astriction because of it, thus catch a cold, dry feces person and the stomach person of stagnating avoid use.
French beans: sweet are flat.Enter spleen, stomach warp.Cure mainly tonic the five internal organs, anti-nausea.Take for a long time, hair can be made not white.The poison of all vegetations can be separated, chew after boiling to eat and drink with liquor, all effectively.General mood in human body is passed through, controls woman's leukorrhea, again can relieving alcoholism, the poison of globe fish.Can cure dysentery, eliminate hot summer weather, warm taste, except remuval of damp and hot, only quench one's thirst.Grind into powder and take down together with vinegar, it is more than to treat cholera vomiting and diarrhoea." detailed outline " cloud: " duricrust Semen Lablab Album, it is sub substantial, and Bai Erwei is yellow, and its gas raw meat is fragrant, and it is warm in nature flat, and obtain and neutralize, the paddy of spleen also.Enter lunar gas to divide, tonneau three is burnt, can change to fall clearly turbid, therefore specially controls the disease of Middle Palace, relieves summer heat and dehumidify and detoxify also.Its soft shell and black magpie look person, its slightly cool in nature, but can be for food, also adjust taste.”
Date: the CAMP contained by red date is the required composition of human body cell energetic supersession, can strengthening muscular strength, dispelling fatigue, hemangiectasis, increase myocardial contractive power, improve myocardial nutrition, having good effect to preventing and treating disease of cardiovascular system; Traditional Chinese medicine theory is thought, red date has the effects such as qi-restoratives benefit gas, nourishing blood and tranquilization, strengthening the spleen and stomach, and red date has good therapeutic effect to illnesss such as chronic hepatitis, cirrhosis, anaemia, anaphylactoid purpuras; Red date contains triterpene compound and CAMP, has stronger anticancer, anti-allergic effects.Date can moisten cardiopulmonary, cough-relieving, tonifying five zang organs, it is deficient to control, except stomach addiction gas, support spleen, flat stomach Qi, logical nine orifices in can also pacifying, help 12 through etc.
Thizoma curculiginis: pungent, temperature, poisonous.Enter kidney, Liver Channel.Kidney-replenishing, strengthening the bones and muscles, loose cold-dampness.Control impotence cold sperm, aconuresis, uterine bleeding, trusted subordinate's crymodynia, cold arthralgia of loins and legs, ulcer, scrofula, the deficiency of yang is cold rushes down.Impotence essence is cold, the diseases such as waist knee is air-cooled, muscles and bones impotence numbness.Modern pharmacology activity research display thizoma curculiginis have immunity moderation, anti-oxidant, protect the liver, antihyperglycemic, tonifying kidney and strengthening yang and anti-osteoporosis, the effect such as anti-inflammatory and adaptation former state.Research shows: thizoma curculiginis can improve the reactivity of removal ovary anesthetized rat hypophysis to injection luteinizing hormone-releasing hormone (LRH) (LRH); Improve ovary to the reactivity of lutropin in blood plasma (LH), thus play the effect of improvement function.Thizoma curculiginis decoction gavage, anterior pituitary of rat weight, ovary weight and uterus weight can be made obviously to increase, ovary HCG/LH receptor-specific adhesion is increased, but on lutropin in blood plasma (LH) level without impact. experiment shows: curculigol preserved material 10g/kg/d is to the rat oral gavage of castration after 7 days, continuous 21 days, castrated rats weight of seminal vesicle obviously increases, and points out it to have Andrin-like action.Thizoma curculiginis aqueous extract has the effect of excitability function.
Matrimony vine: modern study, the fruit of Chinese wolfberry has reduction blood sugar, lipotropy, and can antiatherosclerosis.The fruit of Chinese wolfberry is also for strengthening the body resistance to consolidate the constitution, and production of sperm mends marrow, enriching yin and nourishing kidney, benefiting qi for tranquillization, the good medicine that improves the health, delay senility, evident in efficacy to chronic hepatitis, central retinitis, optic atrophy etc.; Also good therapeutic effect is had to diabetes, pulmonary tuberculosis etc.; To antitumor, protect the liver, step-down, ageing disorders that is hypoglycemic and the elderly's organ failure have very strong improvement result.As tonic invigorator treatment suffer from a deficiency of the kidney each disease and liver and kidney disease curative effect excellent, plasma testosterone cellulose content in human body can be significantly improved, reach the effect of keeping fit.Modern medicine study shows, matrimony vine has obvious inhibitory action to cancer cell in vitro, can be used for preventing the diffusion of cancer cell and strengthening the immunologic function of human body.
Walnut kernel: sweet, temperature.Return kidney, lung, large intestine channel.Function cures mainly: kidney tonifying, warm lung, ease constipation.For soreness and weakness of waist and knees, impotence and seminal emission, the cold of insufficiency type is breathed heavily and is coughed, constipation.
The seed of Chinese dodder: Gan Xinping, enters liver, kidney channel.Tonifying kidney and benefiting sperm, nourishes the liver to improve visual acuity, antiabortive.For caused by liver and kidney deficiency, soreness of waist and knee joint, impotence and seminal emission, frequent urination and enuresis, two blurred visions are dark, the diseases such as fetal irritability.Function tonification liver kidney, controlling nocturnal emission with astringent drugs contracting urine, antiabortive, improving eyesight, antidiarrheal.Suffer from a deficiency of the kidney rush down for impotence and seminal emission, dripping urination, enuresis frequent micturition, soreness and weakness of waist and knees, blurred vision tinnitus, vaginal bleeding due to deficiency of the kidney during pregnancy, fetal irritability, spleen.
Glutinous rice rhizome and root: sweet is flat.Enter liver, lung, kidney three warp.Function cures mainly: reinforcing stomach reg fluid, reducing the asthenic fever, only night sweat.1. " book on Chinese herbal medicine is new again ": " tonifying Qi is reduced phlegm, and stomach is strengthened in enriching yin, except rheumatism.Control cold sensation of the genitalia, antiabortive and blood, treat pernio, metal-inflicted wound." 2. " Chinese medicine voluminous dictionary ": " nourishing the stomach, clearing lung-heat, invigorating the spleen, reducing the asthenic fever." 3. " medicinal material data compilation ": " be night sweat only." 4. " pharmacognosy ": " tonifying lung invigorating the spleen, nourishing the stomach Tianjin."
Maidenhair: bitter, flat.Function cures mainly: clearing heat and promoting diuresis, cough-relieving, pain relieving.For the infection of the upper respiratory tract, dysentery, cough, pertussis, toothache, acute conjunctivitis due to pathogenic wind-fire; Mumps is controlled in external application, mastitis.
Glossy ganoderma: property is sweet, flat.The thoughts of returning home, lung, liver, kidney channel.Cure mainly consumptive disease, cough, asthma, insomnia, indigestion, malignant tumour etc.Animal pharmacology shows experiment: glossy ganoderma has inhibitory action to nervous system, and the circulatory system has step-down and strengthens the effect of cardiac contractile force, has phlegm-dispelling functions to respiratory system, in addition, protects liver in addition, improves immunologic function, antibacterially waits effect.
Barley: Gan Xian is cool.Enter spleen, stomach two warp.Function cures mainly: and stomach, wide intestines, Li Shui.Control and eat stagnant having loose bowels, urine leaching pain, oedema, burn.
Lotus leaf: bitter is flat.Return liver, spleen, stomach warp.Function cures mainly: clearing away summerheat, sending up the lucid yang, cooling blood and hemostasis.For hot summer weather polydipsia, summer heat damp diarrhea, splenasthenic diarrhea, blood-head tells nosebleed, uterine bleeding of having blood in stool.Burnt FOLIUM NELUMBINIS inducing astrigency removing blood stasis and hemostasis.For multiple haemorrhage and postpartum anemic fainting.
Dried orange peel: regulating the flow of Qi and the middle Jiao, eliminating dampness and eliminating phlegm, sharp water defaecation.Cure mainly incoordination between the spleen and the stomach, abdominal distention, do not feel like eating, vomiting hiccup; Phlegm-damp obstructing lung, coughing with a lot of sputum, chest diaphragm is full vexed, vertigo; Oedema, difficult urination, constipation; Acute mastitis sore tinea, middle fish crab poison, wine are malicious.For diseases such as fullness and oppression of chest and abdomen.The pungent loose logical temperature of orange peel, fragrant odour, is longer than and regulates the flow of vital energy, and can enter spleen lung, therefore can go loose sluggishness of lung-QI, again can promoting the circulation of qi wide in, for lung qi gather around stagnant, chest diaphragm ruffian full and the disease such as the taste stagnation of the circulation of vital energy, abdominal fullness and distention.Temperature eliminating dampness and can invigorating the spleen promoting the circulation of qi, therefore be usually used in the diseases such as damp retention in middle-jiao, gastral cavity abdominal distension is vexed, loose stool tongue is greasy, can compatibility rhizoma atractylodis, the bark of official magnolia is with using.Being good at again eliminating dampness and eliminating phlegm, stopping up the conventional key medicine of lung, the many coughs of phlegm for controlling wet phlegm, often use together with the tuber of pinellia, Poria cocos.Reduce for insufficiency of the spleen diet, indigestion, and the disease such as n and V, eliminating dampness and can spleen benefiting and stimulating the appetite, is applicable to the diseases such as weakness of the spleen and the stomach, diet minimizings, indigestion, stool diarrhea, often and the fit applications such as ginseng, the bighead atractylodes rhizome, Poria cocos.Because it can invigorating the spleen, can regulate the flow of vital energy again, therefore the assistant being often used as Qi-tonifying drug makes, and can make tonify without causing stagnation, prevent heap soil or fertilizer over and around the roots from holding back and do swollen effect.In addition, orange peel again can with in, stomach Qi rising, n and V can be controlled.
Paniculate swallowwort: warm in nature, taste is pungent; Dispelling wind is antipyretic, and the promoting flow of qi and blood circulation cures mainly: analgesia, cough-relieving, inducing diuresis for removing edema, promoting blood circulation and detoxication.Treat for stomachache, toothache, rheumatalgia pain, bellyache in menstrual period, chronic bronchitis, ascites, oedema, dysentery, enteritis, traumatic injury, eczema, nettle rash, venomous snake bite.What is fed and raises the rabbit experiment hyperlipemia and experimental atherosclerosismodel that cholesterol diet causes, paniculate swallowwort has the effect reducing serum total cholesterol and beta lipoprotein, and atherosclerosis of aorta and parteriole lipid deposition can be alleviated, thus show that paniculate swallowwort has preventive and therapeutic effect to atherosclerotic.
Embodiment 1 feed addictive 1
Embodiments provide a kind of feed addictive, be made up of following raw material: Chinese medicine additive, enzymatic compositions and vitamine D3, wherein, the ratio of weight and number of Chinese medicine additive, enzymatic compositions and vitamine D3 is 1:1:0.03;
Wherein, in Chinese medicine additive, the parts by weight of each raw medicinal material are: marine alga 18 weight portion, rhizoma atractylodis 17 weight portion, Radix Codonopsis 19 weight portion, caryophyllaceous ginseng 13 weight portion, chrysanthemum 20 weight portion, comfrey 16 weight portion, pollen 15 weight portion, Chinese scholartree leaf 20 weight portion, the membrane of a chicken's gizzard 19 weight portion, trifoliate orange 14 weight portion, fructus amomi 13 weight portion, Chinese yam 15 weight portion, French beans 15 weight portion, date 17 weight portion, thizoma curculiginis 17 weight portion, matrimony vine 21 weight portion, walnut kernel 15 weight portion, the seed of Chinese dodder 15 weight portion, glutinous rice rhizome and root 15 weight portion and maidenhair 13 weight portion.
Enzymatic compositions is made up of zytase, 1,4 beta-glucanase, 'beta '-mannase, cellulase, amylase and protease, and its ratio of weight and number is: 1:1:2:1:2:1.
The preparation method of feed addictive comprises the following steps:
The first step, mixes by ratio of weight and the number of copies by above-mentioned various raw medicinal material, drops into pulverizer and carries out pulverizing or directly shredding, load and decoct in container, add suitable quantity of water and make its submergence medicinal material, soak after 50 minutes, be heated to boiling after 50 minutes, be separated fried liquid, the dregs of a decoction again add water and carry out decoction 2 times, isolate fried liquid respectively at every turn, merge all fried liquid, again after filtering, get filtrate and abandon filter residue;
Second step, after liquid cooling but to be filtered, adding relative to the determining alcohol of concentrated rear liquid weight 2 times is 80-90% ethanol, fully mix, placement is spent the night, and makes it precipitate, obtain filtrate after getting its supernatant liquid filtering next day, sediment determining alcohol be 55% ethanol clean, collect washing lotion and also merge with filtrate, after ethanol is regained in decompression, leave standstill 40 minutes, make precipitation complete, filter, filtrate low-temperature evaporation, obtains paste;
3rd step: paste is put into spray dryer dry, ensure that EAT is at 180 DEG C, leaving air temp 90 DEG C, is ground into 200 order orders subsequently, obtains Chinese medicine additive pulvis;
4th step: by weight Chinese medicine additive, enzymatic compositions and vitamine D3 mixed and obtain feed addictive.
Embodiment 2 feed addictive 2
Embodiments provide a kind of feed addictive, be made up of following raw material: Chinese medicine additive, enzymatic compositions and vitamine D3, wherein, the ratio of weight and number of Chinese medicine additive, enzymatic compositions and vitamine D3 is 1:1:0.05;
Wherein, in Chinese medicine additive, the parts by weight of each raw medicinal material are: marine alga 21 weight portion, rhizoma atractylodis 15 weight portion, Radix Codonopsis 20 weight portion, caryophyllaceous ginseng 12 weight portion, chrysanthemum 16 weight portion, comfrey 15 weight portion, pollen 15 weight portion, Chinese scholartree leaf 18 weight portion, the membrane of a chicken's gizzard 22 weight portion, trifoliate orange 14 weight portion, fructus amomi 13 weight portion, Chinese yam 15 weight portion, French beans 15 weight portion, date 15 weight portion, thizoma curculiginis 15 weight portion, matrimony vine 19 weight portion, walnut kernel 15 weight portion, the seed of Chinese dodder 15 weight portion, glutinous rice rhizome and root 15 weight portion, maidenhair 12 weight portion, glossy ganoderma 20 weight portion, barley 14 weight portion, lotus leaf 13 weight portion, dried orange peel 15 weight portion and paniculate swallowwort 13 weight portion.
Enzymatic compositions is made up of zytase, 1,4 beta-glucanase, 'beta '-mannase, cellulase, amylase and protease, and its ratio of weight and number is: 1:1:2:1:2:1.
The preparation method of feed addictive comprises the following steps:
The first step, mixes by ratio of weight and the number of copies by above-mentioned various raw medicinal material, drops into pulverizer and carries out pulverizing or directly shredding, load and decoct in container, add suitable quantity of water and make its submergence medicinal material, soak after 40 minutes, be heated to boiling after 40 minutes, be separated fried liquid, the dregs of a decoction again add water and carry out decoction 3 times, isolate fried liquid respectively at every turn, merge all fried liquid, again after filtering, get filtrate and abandon filter residue;
Second step, after liquid cooling but to be filtered, adding relative to the determining alcohol of concentrated rear liquid weight 2 times is 80-90% ethanol, fully mix, placement is spent the night, and makes it precipitate, obtain filtrate after getting its supernatant liquid filtering next day, sediment determining alcohol be 60% ethanol clean, collect washing lotion and also merge with filtrate, after ethanol is regained in decompression, leave standstill 40 minutes, make precipitation complete, filter, filtrate low-temperature evaporation, obtains paste;
3rd step: paste is put into spray dryer dry, ensure that EAT is at 190 DEG C, leaving air temp 80 DEG C, is ground into 250 orders subsequently, obtains Chinese medicine additive pulvis;
4th step: by weight Chinese medicine additive, enzymatic compositions and vitamine D3 mixed and obtain feed addictive.
Embodiment 3 Chinese medicine additive
The embodiment of the present invention additionally provides a kind of laying cycle of laying hens Chinese medicine additive, be made up of the raw medicinal material of following parts by weight: marine alga 25 weight portion, rhizoma atractylodis 20 weight portion, Radix Codonopsis 15 weight portion, caryophyllaceous ginseng 10 weight portion, chrysanthemum 13 weight portion, comfrey 20 weight portion, pollen 20 weight portion, Chinese scholartree leaf 25 weight portion, the membrane of a chicken's gizzard 15 weight portion, trifoliate orange 18 weight portion, fructus amomi 16 weight portion, Chinese yam 10 weight portion, French beans 10 weight portion, date 20 weight portion, thizoma curculiginis 20 weight portion, matrimony vine 15 weight portion, walnut kernel 10 weight portion, the seed of Chinese dodder 10 weight portion, glutinous rice rhizome and root 20 weight portion, maidenhair 10 weight portion, glossy ganoderma 25 weight portion, barley 18 weight portion, lotus leaf 15 weight portion, dried orange peel 20 weight portion and paniculate swallowwort 15 weight portion.
Its preparation method comprises the following steps:
The first step, mixes by ratio of weight and the number of copies by various raw medicinal material, drops into pulverizer and carries out pulverizing or directly shredding, load and decoct in container, add suitable quantity of water and make its submergence medicinal material, soak after 45 minutes, be heated to boiling after 45 minutes, be separated fried liquid, the dregs of a decoction again add water and carry out decoction 2 times, isolate fried liquid respectively at every turn, merge all fried liquid, again after filtering, get filtrate and abandon filter residue;
Second step, after liquid cooling but to be filtered, adding relative to the determining alcohol of concentrated rear liquid weight 2 times is 80-90% ethanol, fully mix, placement is spent the night, and makes it precipitate, obtain filtrate after getting its supernatant liquid filtering next day, sediment determining alcohol be 55% ethanol clean, collect washing lotion and also merge with filtrate, after ethanol is regained in decompression, leave standstill 45 minutes, make precipitation complete, filter, filtrate low-temperature evaporation, obtains paste;
3rd step: paste is put into spray dryer dry, ensure that EAT is at 190 DEG C, leaving air temp 80 DEG C, is ground into 250 orders subsequently, obtains Chinese medicine additive.
Toxicity test
Acute toxicity test: application NIH mouse 40, SPF level, male and female half and half, body weight 18 ~ 22g, carries out acute toxicity test.Mouse is divided into two groups at random, often organizes 20, i.e. control group and administration group, fasting 12 hours before experiment; Chinese medicine additive prepared by embodiments of the invention 3 is dissolved in water, (concentration is 6.58g crude drug/ml, maximum concentration) gavage, gavage volume is 5ml/kg(and unit dosage form is 32.9 crude drugs/kg), control group gives normal saline, administration in a day 2 times, delivery time 6 hours, Continuous Observation 14 days after administration, and record mouse toxic reaction and death toll.Experimental result shows: compare with control group, and after administration, mouse has no notable difference, and experiment Continuous Observation 14 days, mouse systemic situation, diet, drinking-water, body weight increase all normal.Therefore the Chinese medicine additive acute toxicity of the embodiment of the present invention 3 is low, clinical drug safety.Test the Chinese medicine additive of the embodiment of the present invention 1 and embodiment 2 respectively according to above-mentioned test method, the results show, the Chinese medicine additive acute toxicity of the embodiment of the present invention 1 and embodiment 2 is low, clinical drug safety.
Long term toxicity test: the Chinese medicine additive of the embodiment of the present invention 3 presses 10.78,20.35 and 33.48g crude drug/kg continuous use 16 weeks (1.0ml/100g body weight to mouse, every day 2 times) and drug withdrawal after 4 weeks, result shows: the index such as hair, behavior, stool and urine, body weight, organ weights, blood picture, hepatic and renal function, blood sugar, blood fat of Chinese medicine of the present invention to mouse all has no significant effect, internal organs naked eyes do not find that difference change and histological indications show, medication 16 weeks and drug withdrawal are after 4 weeks, and Organs of Mice is all without obviously changing.Illustrate that the Chinese medicine additive of the embodiment of the present invention 3 is little to toxicity after mouse long-term prescription, also there is no difference reaction after drug withdrawal, application safety.Respectively the Chinese medicine additive of the embodiment of the present invention 1 and embodiment 2 is tested according to above-mentioned test method, result shows: the index such as hair, behavior, stool and urine, body weight, organ weights, blood picture, hepatic and renal function, blood sugar, blood fat of Chinese medicine additive to mouse of the embodiment of the present invention 1 and embodiment 2 all has no significant effect, internal organs naked eyes do not find that difference change and histological indications show, medication 16 weeks and drug withdrawal are after 4 weeks, and Organs of Mice is all without obviously changing.Illustrate that Chinese medicine additive of the present invention is little to toxicity after mouse long-term prescription, also there is no difference reaction after drug withdrawal, application safety.
Contrast test
The laying hen 400 that experiment selects 30 week age, body weight even, healthy, be divided into 4 groups at random, the feed (embodiment group 1-3) containing embodiment of the present invention 1-3 additive and traditional egg feedstuff (control group) is used to feed 90 days respectively, collect each group of egg every day, often organize random selecting 20 as sample, measure egg size and cholesterol level of vitellus, assay method is high performance liquid chromatography, result is as shown in table 1, and the body weight of experiment fore-and-aft survey laying hen, calculates average daily gain.
Wherein, the feed that embodiment group 1 uses is the conventional feed being added with feed addictive prepared by embodiment 1, and the content of feed addictive is 3% of feed gross weight; The feed that embodiment group 2 uses is the conventional feed being added with feed addictive prepared by embodiment 2, and the content of feed addictive is 2% of feed gross weight; The feed that embodiment group 3 uses is the conventional feed being added with Chinese medicine additive prepared by embodiment 3, and the content of feed addictive is 4% of feed gross weight; Control group is conventional feed.
Conventional feed forms by the raw material of following parts by weight: corn 401 weight portion, wheat 200 weight portion, corn protein powder 50 weight portion, maize alcohol lees 30 weight portion, dregs of beans 150 weight portion, peanut meal 45 weight portion, soya-bean oil 13.6 weight portion, stone flour 13.3 weight portion, calcium monohydrogen phosphate 16 weight portion and salt 3.1 weight portion.
Test manages routinely at chicken house carries out prerun, carries out volume wing number, expelling parasite and immunization inocultation in preliminary trial period.Just carried out before the examination phase dividing into groups (as far as possible in reduction group and between group error), single cage is fed.Free choice feeding, freely drinks water.Carry out routine work record and chicken health status record, experimental result is as shown in table 1.
The table of comparisons of table 1 egg egg size, cholesterol level of vitellus and laying rate
Note: normal data, colleague's shoulder note same letter represents difference not significantly (P > 0.05), and the different alphabetical person of shoulder note represents significant difference (P<0.05).
Data from table 1: the laying hen using the forage feed containing embodiment of the present invention 1-3 additive, its egg size exceeds egg 7.76g, 8.60g and 6.70g of using traditional egg feedstuff to feed laying hen respectively, its cholesterol level of vitellus and conventional feed are fed compared with the cholesterol level of vitellus of laying eggs of laying hen, respectively low go out 4.53mg/g, 4.99mg/g and 4.11mg/g, its laying rate is also apparently higher than the laying rate of laying hen that conventional feed is fed.
After experiment in above-mentioned 90 days terminates, every experimental group is chosen 10 laying hens and is carried out second time test, artificial challenge is carried out to often organizing test chicken, with 5 times of dilutions of culture of Escherichia coli for subsequent use, only, observed and recorded respectively organizes the incidence of disease and the death rate of laying hen to lumbar injection 0.2mL/, duration of test, continue to feed according to the feed mode of above-mentioned test, result of the test is as shown in table 2.
The table 2 challenge test result table of comparisons
Data from table 2: compared with conventional feed, the feed using the present invention to contain additive of the present invention can improve the resistance against diseases of laying hen, reduces the death rate.
Known by contrast experiment, use the laying hen that the egg feedstuff containing embodiment of the present invention 1-3 additive is fed, its egg size, cholesterol level of vitellus and laying rate are all obviously better than the laying hen using conventional feed to feed, but also the resistance against diseases of laying hen can be improved, namely egg feedstuff of the present invention is used, well can not only meet the nutritional need of laying hen, but also the cholesterol level of yolk can be reduced, improve laying rate and egg size.
The foregoing is only preferred embodiment of the present invention, not in order to limit the present invention, within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (6)
1. a laying cycle of laying hens feed addictive, is characterized in that, described feed addictive comprises Chinese medicine additive, enzymatic compositions and vitamin D
3, wherein, described Chinese medicine additive, enzymatic compositions and vitamin D
3ratio of weight and number be 1:1:0.01-0.5, in described Chinese medicine additive, the parts by weight of each raw medicinal material are: marine alga 15-25 weight portion, rhizoma atractylodis 10-20 weight portion, Radix Codonopsis 15-25 weight portion, caryophyllaceous ginseng 10-15 weight portion, chrysanthemum 13-24 weight portion, comfrey 10-20 weight portion, pollen 10-20 weight portion, Chinese scholartree leaf 15-25 weight portion, the membrane of a chicken's gizzard 15-25 weight portion, trifoliate orange 10-18 weight portion, fructus amomi 10-16 weight portion, Chinese yam 10-20 weight portion, French beans 10-20 weight portion, date 10-20 weight portion, thizoma curculiginis 10-20 weight portion, matrimony vine 15-25 weight portion, walnut kernel 10-20 weight portion, seed of Chinese dodder 10-20 weight portion, glutinous rice rhizome and root 10-20 weight portion and maidenhair 10-15 weight portion.
2. laying cycle of laying hens feed addictive according to claim 1, is characterized in that, described enzymatic compositions is one or more in zytase, 1,4 beta-glucanase, 'beta '-mannase, cellulase, amylase, phytase or protease.
3. laying cycle of laying hens feed addictive according to claim 1, it is characterized in that, in described Chinese medicine additive, the parts by weight of each raw medicinal material are: marine alga 18 weight portion, rhizoma atractylodis 17 weight portion, Radix Codonopsis 19 weight portion, caryophyllaceous ginseng 13 weight portion, chrysanthemum 20 weight portion, comfrey 16 weight portion, pollen 15 weight portion, Chinese scholartree leaf 20 weight portion, the membrane of a chicken's gizzard 19 weight portion, trifoliate orange 14 weight portion, fructus amomi 13 weight portion, Chinese yam 15 weight portion, French beans 15 weight portion, date 17 weight portion, thizoma curculiginis 17 weight portion, matrimony vine 21 weight portion, walnut kernel 15 weight portion, the seed of Chinese dodder 15 weight portion, glutinous rice rhizome and root 15 weight portion and maidenhair 13 weight portion.
4. a laying cycle of laying hens feed addictive, is characterized in that, described feed addictive comprises Chinese medicine additive, enzymatic compositions and vitamin D
3, wherein, described Chinese medicine additive, enzymatic compositions and vitamin D
3ratio of weight and number be 1:1:0.01-0.5, in described Chinese medicine additive, the parts by weight of each raw medicinal material are: marine alga 15-25 weight portion, rhizoma atractylodis 10-20 weight portion, Radix Codonopsis 15-25 weight portion, caryophyllaceous ginseng 10-15 weight portion, chrysanthemum 13-24 weight portion, comfrey 10-20 weight portion, pollen 10-20 weight portion, Chinese scholartree leaf 15-25 weight portion, the membrane of a chicken's gizzard 15-25 weight portion, trifoliate orange 10-18 weight portion, fructus amomi 10-16 weight portion, Chinese yam 10-20 weight portion, French beans 10-20 weight portion, date 10-20 weight portion, thizoma curculiginis 10-20 weight portion, matrimony vine 15-25 weight portion, walnut kernel 10-20 weight portion, seed of Chinese dodder 10-20 weight portion, glutinous rice rhizome and root 10-20 weight portion, maidenhair 10-15 weight portion, glossy ganoderma 15-25 weight portion, barley 10-18 weight portion, lotus leaf 10-15 weight portion, dried orange peel 10-20 weight portion and paniculate swallowwort 10-15 weight portion.
5. laying cycle of laying hens feed addictive according to claim 4, it is characterized in that, in described Chinese medicine additive, the parts by weight of each raw medicinal material are: marine alga 21 weight portion, rhizoma atractylodis 15 weight portion, Radix Codonopsis 20 weight portion, caryophyllaceous ginseng 12 weight portion, chrysanthemum 16 weight portion, comfrey 15 weight portion, pollen 15 weight portion, Chinese scholartree leaf 18 weight portion, the membrane of a chicken's gizzard 22 weight portion, trifoliate orange 14 weight portion, fructus amomi 13 weight portion, Chinese yam 15 weight portion, French beans 15 weight portion, date 15 weight portion, thizoma curculiginis 15 weight portion, matrimony vine 19 weight portion, walnut kernel 15 weight portion, the seed of Chinese dodder 15 weight portion, glutinous rice rhizome and root 15 weight portion, maidenhair 12 weight portion, glossy ganoderma 20 weight portion, barley 14 weight portion, lotus leaf 13 weight portion, dried orange peel 15 weight portion and paniculate swallowwort 13 weight portion.
6. a laying cycle of laying hens Chinese medicine additive, it is characterized in that, described Chinese medicine additive is made up of the raw medicinal material of following parts by weight: marine alga 15-25 weight portion, rhizoma atractylodis 10-20 weight portion, Radix Codonopsis 15-25 weight portion, caryophyllaceous ginseng 10-15 weight portion, chrysanthemum 13-24 weight portion, comfrey 10-20 weight portion, pollen 10-20 weight portion, Chinese scholartree leaf 15-25 weight portion, the membrane of a chicken's gizzard 15-25 weight portion, trifoliate orange 10-18 weight portion, fructus amomi 10-16 weight portion, Chinese yam 10-20 weight portion, French beans 10-20 weight portion, date 10-20 weight portion, thizoma curculiginis 10-20 weight portion, matrimony vine 15-25 weight portion, walnut kernel 10-20 weight portion, seed of Chinese dodder 10-20 weight portion, glutinous rice rhizome and root 10-20 weight portion, maidenhair 10-15 weight portion, glossy ganoderma 15-25 weight portion, barley 10-18 weight portion, lotus leaf 10-15 weight portion, dried orange peel 10-20 weight portion and paniculate swallowwort 10-15 weight portion.
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| CN104206905B (en) * | 2014-09-02 | 2016-09-14 | 赵建红 | For reducing the feed additive of cholesterol content in eggs |
| CN104351139B (en) * | 2014-12-01 | 2016-09-07 | 王德 | A kind of method increasing egg yolk |
| CN105981958A (en) * | 2016-03-07 | 2016-10-05 | 倪皖生 | Layer feed capable of increasing laying rate of layers and preparation method thereof |
| CN106689779A (en) * | 2016-11-28 | 2017-05-24 | 徐州培源生物科技有限公司 | A production formula and production method of egg for treating male prostate disease |
| CN108094696A (en) * | 2017-12-27 | 2018-06-01 | 福建光阳蛋业股份有限公司 | A kind of laying hen lotus leaf feed and preparation method thereof |
| CN115814462A (en) * | 2022-12-22 | 2023-03-21 | 中国科学院西北高原生物研究所 | Preparation method of silphium perfoliatum extract, feed additive and application of feed additive |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1911078A (en) * | 2006-08-12 | 2007-02-14 | 尚秀园 | Recipe of herb medicine additive of forage for improving egg prodn, and egg quality |
| CN101181018A (en) * | 2007-12-13 | 2008-05-21 | 济南和美华饲料有限公司 | Hen feedstuff for producing healthy egg |
| CN102940153A (en) * | 2012-12-06 | 2013-02-27 | 山东新希望六和集团有限公司 | Poultry feed for improving meat quality and egg quality |
| CN103027199A (en) * | 2011-09-30 | 2013-04-10 | 宋必成 | Nuisanceless green chicken feed |
| CN103355555A (en) * | 2013-08-05 | 2013-10-23 | 山东新希望六和集团有限公司 | Feed for laying hen in egg-laying peak stage and preparation method thereof |
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Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1911078A (en) * | 2006-08-12 | 2007-02-14 | 尚秀园 | Recipe of herb medicine additive of forage for improving egg prodn, and egg quality |
| CN101181018A (en) * | 2007-12-13 | 2008-05-21 | 济南和美华饲料有限公司 | Hen feedstuff for producing healthy egg |
| CN103027199A (en) * | 2011-09-30 | 2013-04-10 | 宋必成 | Nuisanceless green chicken feed |
| CN102940153A (en) * | 2012-12-06 | 2013-02-27 | 山东新希望六和集团有限公司 | Poultry feed for improving meat quality and egg quality |
| CN103355555A (en) * | 2013-08-05 | 2013-10-23 | 山东新希望六和集团有限公司 | Feed for laying hen in egg-laying peak stage and preparation method thereof |
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Effective date of registration: 20160429 Address after: 224000 Jiangsu Province, Yancheng City Dongtai Economic Development Zone weft nine road No. 9 Patentee after: YANCHENG LIUHE FEED CO.,LTD. Address before: 266061 Shandong city of Qingdao province Chengyang Jihongtan Street Green Industrial Park Patentee before: SHANDONG NEW HOPE LIUHE GROUP Co.,Ltd. |
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