Summary of the invention
The invention provides a kind of Chinese medicine ointment and preparation method for the treatment of cervical spondylosis, Chinese medicine ointment of the present invention selects high-quality Chinese crude drug scientific compatibility to make, there is effect of channels sootheing and network vessel quickening, relieving spasm to stop pain, blood circulation promoting and blood stasis dispelling, loose wind dampness removing, strain for a long time for cervical vertebra, the treatment of the symptom such as numb limbs and tense tendons, pain and limitation of activity that hyperosteogeny, cervical spondylosis cause, speed of action is fast, evident in efficacy, safe and reliable, without any side effects, with low cost, use simple, can arrive the object for the treatment of both the principal and secondary aspects of a disease to the treatment of cervical spondylosis, total effective rate reaches 94.3%.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Treat a Chinese medicine ointment for cervical spondylosis, raw material composition and the parts by weight of making described Chinese medicine ointment effective ingredient are:
Rhizoma Tupistrae Chinensis 56 ~ 82 parts of Semen Astragali Complanatis 53 ~ 79 parts of Folium et Ramulus Callicarpae nudiflorae 45 ~ 71 portions of Lignum Sappans 40 ~ 67 parts
Herba Lycopodii 40 ~ 66 parts of Herba rutaes 36 ~ 65 parts of Herba Sambuci Chiensis 36 ~ 65 parts of Herba Arundinae Chinensiss 32 ~ 59 parts
Flos Jasmini Nudiflori 31 ~ 58 parts of Herba Asari Forbesii 26 ~ 55 parts of Cortex Cinnamomi Burmanniis 24 ~ 54 portions of Caulis Trachelospermis 20 ~ 48 parts
Radix Ariliae 19 ~ 42 portions of Rhizoma et radix veratri (Radix Rhizoma Veratri)s 19 ~ 42 parts of Rhizoma Ligustici 13 ~ 34 Fen Caulis Endadae phaseoloidis 11 ~ 30 parts.
Raw material composition and the parts by weight of making described Chinese medicine ointment effective ingredient are:
Rhizoma Tupistrae Chinensis 60 ~ 78 parts of Semen Astragali Complanatis 57 ~ 75 parts of Folium et Ramulus Callicarpae nudiflorae 49 ~ 67 portions of Lignum Sappans 45 ~ 63 parts
Herba Lycopodii 44 ~ 62 parts of Herba rutaes 40 ~ 60 parts of Herba Sambuci Chiensis 40 ~ 60 parts of Herba Arundinae Chinensiss 36 ~ 54 parts
Flos Jasmini Nudiflori 35 ~ 53 parts of Herba Asari Forbesii 30 ~ 50 parts of Cortex Cinnamomi Burmanniis 29 ~ 49 portions of Caulis Trachelospermis 25 ~ 43 parts
Radix Ariliae 23 ~ 39 portions of Rhizoma et radix veratri (Radix Rhizoma Veratri)s 23 ~ 39 parts of Rhizoma Ligustici 17 ~ 30 Fen Caulis Endadae phaseoloidis 15 ~ 26 parts.
Raw material composition and the parts by weight of making described Chinese medicine ointment effective ingredient are:
Rhizoma Tupistrae Chinensis 65 ~ 73 parts of Semen Astragali Complanatis 62 ~ 70 parts of Folium et Ramulus Callicarpae nudiflorae 54 ~ 62 portions of Lignum Sappans 50 ~ 58 parts
Herba Lycopodii 49 ~ 57 parts of Herba rutaes 45 ~ 55 parts of Herba Sambuci Chiensis 45 ~ 55 parts of Herba Arundinae Chinensiss 41 ~ 49 parts
Flos Jasmini Nudiflori 40 ~ 48 parts of Herba Asari Forbesii 35 ~ 45 parts of Cortex Cinnamomi Burmanniis 34 ~ 44 portions of Caulis Trachelospermis 30 ~ 38 parts
Radix Ariliae 27 ~ 35 portions of Rhizoma et radix veratri (Radix Rhizoma Veratri)s 27 ~ 35 parts of Rhizoma Ligustici 20 ~ 27 Fen Caulis Endadae phaseoloidis 18 ~ 22 parts.
Raw material composition and the parts by weight of making described Chinese medicine ointment effective ingredient are:
Rhizoma Tupistrae Chinensis 69 parts of Semen Astragali Complanatis 66 parts of Folium et Ramulus Callicarpae nudiflorae 58 portions of Lignum Sappans 54 parts
Herba Lycopodii 53 parts of Herba rutaes 50 parts of Herba Sambuci Chiensis 50 parts of Herba Arundinae Chinensiss 45 parts
Flos Jasmini Nudiflori 44 parts of Herba Asari Forbesii 40 parts of Cortex Cinnamomi Burmanniis 39 portions of Caulis Trachelospermis 34 parts
Radix Ariliae 31 portions of Rhizoma et radix veratri (Radix Rhizoma Veratri)s 31 parts of Rhizoma Ligustici 23 Fen Caulis Endadae phaseoloidis 20 parts.
Treat a preparation method for the Chinese medicine ointment of cervical spondylosis, comprise following processing step:
(1) Rhizoma Tupistrae Chinensis, Semen Astragali Complanati, Flos Jasmini Nudiflori and Cortex Cinnamomi Burmannii are put into container, carry out pulverization process, grind into powder, cross 200 order fine powders, for subsequent use;
(2) Folium et Ramulus Callicarpae nudiflorae, Lignum Sappan, Herba Sambuci Chiensis, Herba Arundinae Chinensis, Radix Ariliae, Rhizoma et radix veratri (Radix Rhizoma Veratri) and Rhizoma Ligustici are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, being condensed into relative density at 60 DEG C is the thick paste of 1.13 ~ 1.17, for subsequent use;
(3) by Herba Lycopodii, Herba Asari Forbesii, Caulis Trachelospermi with Caulis Endadae phaseoloidis is cleaned, immerse the alcohol solution dipping 3 ~ 4 hours of 70% of 6 times amount, heating and refluxing extraction 2 ~ 3 hours, reclaim ethanol, filter, by the thick paste of relative density 1.11 ~ 1.13 under filtrate simmer down to 60 DEG C of environment, for subsequent use;
(4) cleaned by Herba rutae, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(5) by fine powder, thick paste and the juice mixing obtained by above-mentioned steps (1) ~ (4), make ointment, obtain the Chinese medicine ointment for the treatment of cervical spondylosis of the present invention.
The property of medicine of the present invention's Chinese medicine used is as follows:
Rhizoma Tupistrae Chinensis: sweet in the mouth, micro-hardship, cold in nature.Nourishing yin and purging fire, promoting blood flow to regulate menstruation.Control consumptive fever cough, rheumatic arthralgia, menoxenia, traumatic injury." Shaanxi Chinese herbal medicine " carries: " except rheumatism, clearing away heat-fire, pain easing and hemostasis, regulating menstruation and activating blood, YIN nourishing tonify deficiency.Cure mainly rheumatic arthritis, lumbago, skelalgia of rheumatism, traumatic injury, impairment caused by overstrain, menoxenia, hectic fever due to YIN-deficiency consumptive fever.”
Semen Astragali Complanati: sweet in the mouth, warm in nature; Enter liver, kidney channel.Invigorating the liver and kidney controlling nocturnal emission with astringent drugs, reducing urination improving eyesight.Cure mainly the soreness of waist and knee joint that Liver and kidney void causes, dizziness and blurred vision, seminal emission premature ejaculation, the enuresis, frequent micturition, leukorrhagia, the diseases such as poor vision.Modern medicine study confirms, Semen Astragali Complanati containing retinoid material, fatty oil, tannin, have dispel the wind antipyretic, the effect of tonifying kidney for improving eyesight.
Folium et Ramulus Callicarpae nudiflorae: micro-hardship, property is put down.Hemostasis and anti-inflammation, stasis-dispelling and pain-killing.That controls that pneumorrhagia type leptospirosis, pulmonary tuberculosis, lung abscess, lobar pneumonia etc. cause is hemorrhage, the upper gastrointestinal hemorrhage that Peptic Ulcers etc. cause, thrombocytopenic purpura, hematuria, wound hemorrhage, influenza, burn, suppurative skin ulcer, cervical erosion, traumatic injury, rheumatalgia." south of the Five Ridges gather medicinal herbs record " carries: " decoct washing traumatic injury wound, can eliminating blood stasis to promote regeneration of blood.As swelling due to wind, leaf is decocted washing, get its stalk and lean pork decoction, can wind dispelling detumescence.”
Lignum Sappan: sweet in the mouth, salty, property is pungent cool; GUIXIN, liver, stomach, spleen channel.Dispelling phlegm and alleviating pain, invigorating blood and dispelling wind, blood circulation promoting and blood stasis dispelling, subduing swelling and relieving pain.Cure mainly married woman's amenorrhea due to stagnation of blood, dysmenorrhea, postpartum stagnation cardiac and abdominal pain, puerperal blood faints, carbuncle, traumatic injury, tetanus." Japan hanako materia medica " carries: " evacuation of pus pain relieving, subduing inflammation flutters damage blood stasis, woman's aphonia, and blood is kept silent, and dysentery with red and white feces is rear point shoot also.”
Herba Lycopodii: bitter in the mouth, pungent, warm in nature; Return Liver Channel.Expelling wind and cold, dehumidifying detumescence, relaxing muscles and tendons and activating QI and blood in the collateral.For anemofrigid-damp arthralgia, muscle arteries and veins contracture pain carbuncle; External is controlled osteopatia sprain and is swollen and ache." the SHENGCAO property of medicine standby will " carries: " detumescence, except rheumatism.Infusing drugs in wine is drunk, relaxing muscles and tendons and activating QI and blood in the collateral.It effects a radical cure depressed pain, and damage, internal injury caused by metallic tool, removes phlegm and relieving cough.”
Herba rutae: acrid in the mouth, micro-hardship, cold in nature; Return lung, kidney, liver, heart channel.Expelling wind and clearing away heat, promoting blood circulation to remove blood stasis, subduing swelling and detoxicating.Cure mainly cold, fever, infantile hyperpyrexia infantile convulsion, dysmenorrhea, amenorrhea, traumatic injury, pathopyretic ulcer, infantile eczema, snake bite and insect sting." Nanning City's medicine will " carries: " bring down a fever and dispel the wind, inducing diuresis to remove edema.Control fever of children infantile convulsion, rheumatic ostalgia.”
Herba Sambuci Chiensis: bitter in the mouth, pungent, cold in nature; Return Liver Channel.Soothing liver and strengthening spleen, blood circulation promoting and blood stasis dispelling, inducing diuresis to remove edema.For acute viral hepatitis, oedema due to nephritis, rheumatalgia, dislocation, oedema due to nephritis, beriberi edema, urticaria, injury from falling down, fracture." herbal classic " carries: " all numbness between main bone, spasm of the limbs soreness, the cold pain of knee joint, impotence, deficiency of losing heart, swelling of the feet.”
Herba Arundinae Chinensis: bitter in the mouth, property is put down.Heat-clearing and toxic substances removing, expelling wind and removing dampness.Cure mainly pyretic stranguria, jaundice, edema, beriberi edema, hernia is suffered from abdominal pain, rheumatic arthralgia, venom, sore and toxic, traumatic injury." choosing of Simao, Yunnan Chinese herbal medicine " carries: " heat-clearing and toxic substances removing, wind-damp dispelling, antiinflammatory, diuresis.Treating rheumatic lumbago and skelalgia, stomachache, urinary tract infection, beriberi edema, alimentary toxicosis.”
Flos Jasmini Nudiflori: bitter in the mouth, sweet, puckery, property is put down.Removing toxic substances and promoting subsidence of swelling, diuresis is stopped blooding, pain relieving.For fever and headache, urine burning pain, ulcer of the lower limb, traumatic injury, traumatic hemorrhage, stomatitis, carbuncle furuncle and phyma poison, pruritus vulvae." Guizhou folk medicine " carries: " antipyretic diuresis.Control fever and headache, urine burning pain.
Herba Asari Forbesii: acrid in the mouth, warm in nature, mild toxicity; Return lung, liver, kidney, urinary bladder channel.Expelling wind and cold, expectorant diuretic, promoting blood circulation and stopping pain.Cure mainly anemofrigid cold, phlegm retention is breathed with cough, edema, anemofrigid-damp arthralgia, traumatic injury, headache, toothache, stomachache, and eruptive disease is suffered from abdominal pain, scrofula, toxic swelling, venom." Jiangsu medical material will " carries: " diaphoresis is eliminated the phlegm.Cure cold headache, toothache, aphtha of the mouth and tongue.”
Cortex Cinnamomi Burmannii: acrid in the mouth, micro-sweet, warm in nature; Return spleen channel.Warming middle-JIAO to relieve pain, expelling wind and cold, removing toxic substances and promoting subsidence of swelling, hemostasis.Cure mainly cold stomachache, stomachache is had loose bowels, inappetence, anemofrigid-damp arthralgia, lumbago and skelalgia, traumatic injury, wound hemorrhage, furuncle toxic swelling.Guangzhou army " conventional Chinese herbal medicine handbook " carries: " expelling wind and cold, warming middle-JIAO to relieve pain.Control cold stomachache, abdominal distention, diarrhoea.”
Caulis Trachelospermi: bitter in the mouth, cold nature; GUIXIN, liver, kidney channel.Dispelling wind and removing obstruction in the collateral, removing heat from blood is subsided a swelling.For beriberoid pyretic arthralgia, the contracture of muscle arteries and veins, soreness of waist and knee joint, sore throat, carbuncle, injury from falling down.Modern medicine study confirms, Caulis Trachelospermi 50% decoct has inhibitory action to staphylococcus aureus, shigella flexneri and Bacillus typhi.
Radix Ariliae: sweet in the mouth, slightly warm in nature is nontoxic; Enter kidney, urinary bladder channel.Tranquilizing soporific, antalgic and inflammation relieving." property of medicine opinion " carries, and " in controlling, all rheumatism is cold, and to dyspnea gas, musculus cutaneus hardship is itched, brothers' spasm and pain, strain, main air poison toothache.”
Rhizoma et radix veratri (Radix Rhizoma Veratri): acrid in the mouth, hardship, cold in nature, poisonous.Eliminate the phlegm, emetic, parasite killing.Stop up for middle wind-phlegm, epilepsy, malaria, fracture; Scabies is controlled in external, fly eradication maggot.Pharmacological evaluation shows, Rhizoma et radix veratri (Radix Rhizoma Veratri) 1%-5% infusion has strong toxic action to mosquito, fly, flea, louse.Rhizoma Ligustici: acrid in the mouth, warm in nature; Return urinary bladder channel.Expelling wind and cold, removing damp and stopping pain.For anemofrigid cold, top, mountain peak pain, rheumatic arthralgia." pearl sac " carries: " control TAI YANG headache, parietal headache, Great Cold violates brain, and pain connects tooth cheek." modern medicine study confirmation, Rhizoma Ligustici neutral oil has calmness, analgesia, antipyretic and antiinflammatory action, and can suppress intestinal and uterine smooth muscle, and can also obviously slow down keto consumpting speed.
Caulis Endadae phaseoloidis: bitter in the mouth, puckery, property is put down, poisonous; Return kidney channel.Expelling wind and removing dampness, promoting blood circulation to remove obstruction in the collateral.Cure mainly rheumatic arthralgia, traumatic injury, lumbar muscle strain, numb limbs and tense tendons." register planted by Guangxi medicine " carries: " stimulate the menstrual flow, the skin ulcer that disappears swells, dispelling the wind and dampness pathogens lumbago.”
The present invention compared with prior art, has following beneficial effect:
Chinese medicine ointment of the present invention selects high-quality Chinese crude drug scientific compatibility to make, there is effect of channels sootheing and network vessel quickening, relieving spasm to stop pain, blood circulation promoting and blood stasis dispelling, loose wind dampness removing, strain for a long time for cervical vertebra, the treatment of the symptom such as numb limbs and tense tendons, pain and limitation of activity that hyperosteogeny, cervical spondylosis cause, speed of action is fast, evident in efficacy, safe and reliable, without any side effects, with low cost, use simple, can arrive the object for the treatment of both the principal and secondary aspects of a disease to the treatment of cervical spondylosis, total effective rate reaches 94.3%.
Embodiment 5
The raw material composition of Chinese medicine ointment effective ingredient of the present invention and weight are:
Rhizoma Tupistrae Chinensis 60g Semen Astragali Complanati 57g Folium et Ramulus Callicarpae nudiflorae 49g Lignum Sappan 45g
Herba Lycopodii 44g Herba rutae 40g Herba Sambuci Chiensis 40g Herba Arundinae Chinensis 36g
Flos Jasmini Nudiflori 35g Herba Asari Forbesii 30g Cortex Cinnamomi Burmannii 29g Caulis Trachelospermi 25g
Radix Ariliae 23g Rhizoma et radix veratri (Radix Rhizoma Veratri) 23g Rhizoma Ligustici 17g Caulis Endadae phaseoloidis 15g.
The Chinese medicine ointment preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Clinical data:
1, case selection:
As the Chinese medicine ointment for the treatment of cervical spondylosis, select the routine clinical observation of Patients with Cervical Spondylopathy 140 of making a definite diagnosis, patient is divided into treatment group and matched group two groups at random, treatment group 70 example, wherein male 32 example, women 38 example, 50 ~ 73 years old age, 61.5 years old mean age, the course of disease 1 ~ 12 year; Matched group 70 example, wherein male 33 example, women 37 example, 51 ~ 72 years old age, 61.5 years old mean age, the course of disease 1 ~ 11 year;
The course of disease, the degrees of symptoms for the treatment of group and matched group two groups of cases are basically identical, without significant difference, have comparability.
2, Chinese medicine ointment is selected:
Treatment group takes Chinese medicine ointment of the present invention, external, and cleaned in affected part and dry, getting appropriate ointment uniform application in affected part, every day 2 times, 12 days is 1 course for the treatment of, takes 2 ~ 3 courses for the treatment of continuously, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Matched group is taken neck and is led to granule, and boiled water is taken after mixing it with water, one time 20 grams, 3 times on the one, the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
3, efficacy determination:
(1) cure: symptom all disappears, and physical recovery is normal.
(2) effective: symptom obviously alleviates, health is clearly better.
(3) effective: symptom alleviates to some extent, and health takes a turn for the better to some extent.
(4) invalid: by treating rear symptom without alleviating or increasing the weight of.
4, result:
Above result display, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Model case is illustrated:
1, week certain, female, 50 years old, people from Linyi, Shandong.Patient occurred before 2 years that cervical region acid is swollen, pain, obviously increased the weight of during Changes in weather, and the treatments such as row medicine, physical therapy, pin cutter, can temporary relief of symptoms.Rear symptom obviously increases the weight of and occurs left arm pain, fail to respond to any medical treatment through multi-medicament, existing conditions of patients increases the weight of, gradually in the capable cervical vertebra magnetic resonance examination of local hospital, be diagnosed as prolapse of cervical intervertebral disc, doctor advised uses Chinese medicine ointment of the present invention, and after using 1 course for the treatment of of Chinese medicine ointment of the present invention, above-mentioned symptom is obviously alleviated, after using 2 courses for the treatment of of Chinese medicine ointment of the present invention, recovery from illness, physical recovery is normal, follows up a case by regular visits to and does not recur so far.
2, Feng, man, 53 years old, people from yan-an.Patient suffers from cervical spondylosis for many years, drug administration is treated, any improvement is had no after taking a period of time, introduce to our hospital through friend, after using 1 course for the treatment of of Chinese medicine ointment of the present invention, symptom is clearly better, after using 2 courses for the treatment of of Chinese medicine ointment of the present invention, transference cure, physical recovery is normal, follows up a case by regular visits to without recurrence after 1 year.
3, Chen, man, 58 years old, people from Dandong.Patient's restriction of neck motion, goes hospital admission to find: cervical region limited range of motion, and can look into and obvious pressure pain point, test (+) of craning one, neck rotation test (+), two lower-limb muscular strength, muscular tension can.Cervical vertebra magnetic resonance is shown: C5/6 intervertebral disk hernia, and corresponding spinal cord plane still can.Through expert group's consultation of doctors after patient admits, comprehensive patient's state of an illness feature, suggestion uses Chinese medicine ointment of the present invention, after using 1 course for the treatment of, patient body recovers good, after using 2 courses for the treatment of of Chinese medicine ointment of the present invention, the former symptom of patient's readme disappears already completely, daily life, work and ill before be as good as.
4, all certain, female, 62 years old, Nanping, Fujian people.Patient suffers from cervical spondylosis more than 5 years, remove too much family hospital admission, take multiple Drug therapy, have no any improvement, to our hospital upon somebody's introduction, after using 1 course for the treatment of of Chinese medicine ointment of the present invention, above-mentioned symptom is obviously alleviated, after continuing to use 2 courses for the treatment of of Chinese medicine ointment of the present invention, former transference cure completely without, physical recovery is normal, follows up a case by regular visits to without recurrence after half a year.
5, certain is defended, man, 69 years old, Yancheng, Jiangsu Province people.Patient's wind-engaging is caught a cold neck root pain on the left of aftersensation, uses multiple method to treat, and all has no sign of improvement, sometimes hurt like hell, take some analgesic, after drug withdrawal, the pain increased, introduces through neighbours, use Chinese medicine ointment of the present invention, after using 1 course for the treatment of, pain symptom obviously alleviates, after continuing 1 course for the treatment of of use, pain symptom disappears, and follows up a case by regular visits to without recurrence after 3 months.
6, Shen, female, 71 years old, ShaoXing,ZheJiang people.Patient's shoulder, upper arm pain, increase the weight of when cough, sneeze.Removing hospital admission, be diagnosed as cervical spondylosis, all having no improvement with crossing a lot of Drug therapy, to our hospital afterwards, after using 1 course for the treatment of of Chinese medicine ointment of the present invention, above-mentioned symptom is clearly better, after continuing to use 1 course for the treatment of of Chinese medicine ointment of the present invention, above-mentioned symptom disappears, and follows up a case by regular visits to without recurrence after 1 year.