CN103784571A - Orthopedic hot compress medicine - Google Patents
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Abstract
本发明公开了一种骨科热敷药,由伸筋草、透骨草、海桐皮、木瓜、防风、地枫、独活、赤芍、红花、骨碎补、急性子、川椒、乳香、白芷、川牛膝、桂枝及大青盐等中药按配比混合组成,经过传统中药粉末的制备方法,混合均匀,过二号筛,粉成粗粉,分装为20袋后备用。使用方法为:取两袋放入水盆内浸泡两分钟后放在蒸锅内加热蒸15分钟后,取出一袋药稍凉放在患处热敷,药凉再放回锅内加热,同时取出另一袋药同样操作,反复数次,每日一至二次,连用七天为一个疗程。本发明主治跌打损伤、瘀血肿痛、筋骨诸痛、风寒湿性腰痛、关节痛、风湿及类风湿类疾病,临床验证,总有效率达85%以上。The invention discloses a kind of orthopedic hot compress medicine, which is composed of Shenjincao, Tugucao, Pittogonia bark, papaya, Fangfeng, Difeng, Duhuo, red peony, safflower, Drynaria rhizome, acute child, Sichuan pepper, frankincense, Angelica dahurica Traditional Chinese medicines such as Achyranthes bidentata, Cassia twig and Daqing salt are mixed according to the proportion. After the preparation method of traditional Chinese medicine powder, they are evenly mixed, passed through a No. 2 sieve, powdered into coarse powder, and packed into 20 bags for later use. The method of use is: take two bags and put them in a water basin to soak for two minutes, put them in a steamer and steam them for 15 minutes, then take out one bag of medicine to cool slightly and put it on the affected area for hot compress, put it back into the pot to heat when the medicine is cool, and take out another bag at the same time The bag medicine is operated in the same way, repeated several times, once or twice a day, and seven consecutive days is a course of treatment. The present invention mainly treats bruises, blood stasis, swelling and pain, all pains of muscles and bones, lumbago due to wind-cold and dampness, arthralgia, rheumatism and rheumatoid diseases, and the total effective rate reaches more than 85% through clinical verification.
Description
所属技术领域Technical field
本发明属于医用中药技术领域,具体地说是涉及到一种骨科热敷药。The invention belongs to the technical field of medical traditional Chinese medicines, and in particular relates to a hot compress medicine for orthopedics.
背景技术Background technique
众所周知,在医学临床中,跌打损伤、瘀血肿痛、筋骨诸痛、风寒湿性腰痛、关节痛、风湿及类风湿是人类的常见病、多发病。多年以来,西医治疗这类疾病主要采用消炎镇痛类西药,或内服,或外敷,表面上缓解了病症,日后经常复发,不能彻底治愈,也就是只能治标不能治本,长期服用消炎镇痛类西药容易形成药物依赖,而且引起并发症也日趋增多,对肾脏功能损害较大,摧残着人的身心健康,缩短着人类的寿命,实践证明西医或西药方法难以使这类疾病得到根治。多年来,中医学对这类顽症的治疗和调养积累了许多经验,包括病因病机、辨证论治规律、中药有效药物筛选和综合防治等方面,形成了许多新理论与新方法,取得了一系列新的成果。中医理论认为,对于跌打损伤、瘀血肿痛、筋骨诸痛、风寒湿性腰痛、关节痛、风湿及类风湿等疾病,从整体观念出发,辨证施治,以活血散肿、散风祛湿为治疗原则,采用内外兼治的治疗方法,可达到满意的疗效。其中热熨法作为中医骨科的一种传统的常用外治方法,早在明代医籍《普济方》中就有记载,选用温经散寒、行气活血、通络止痛的药物,加热后热敷患处,可使药效借助热力作用于局部,达到治愈的目的。热熨法作为传统的治疗方法,所采用的中药药物种类很多,所配置而成的药方也很多,其性能、功效各有所长。通过在传统的药方基础上,结合中医理论及实践,配置疗效更好的用于治疗跌打损伤、瘀血肿痛、筋骨诸痛、风寒湿性腰痛、关节痛、风湿及类风湿类疾病的骨科热敷药,是中医领域不断追求的目标,也是本领域的中药课题。As we all know, in clinical medicine, bruises, blood stasis, swelling and pain, pains in muscles and bones, lumbago due to wind-cold and dampness, arthralgia, rheumatism and rheumatoid are common and frequently-occurring diseases of human beings. For many years, Western medicine has mainly used anti-inflammatory and analgesic western medicines to treat such diseases, orally or externally, which relieved the symptoms on the surface, but often relapsed in the future, and could not be completely cured, that is, they could only treat the symptoms but not the root cause. Long-term use of anti-inflammatory and analgesic drugs Western medicine is easy to form drug dependence, and causes more and more complications. It damages kidney function, destroys people's physical and mental health, and shortens human life. Practice has proved that Western medicine or Western medicine methods are difficult to cure these diseases. Over the years, Chinese medicine has accumulated a lot of experience in the treatment and recuperation of such chronic diseases, including etiology and pathogenesis, syndrome differentiation and treatment rules, effective drug screening of traditional Chinese medicine, and comprehensive prevention and treatment. Many new theories and methods have been formed, and a series of new achievements have been made. the results. The theory of traditional Chinese medicine believes that for diseases such as bruises, blood stasis, swelling and pain, pain in muscles and bones, lumbago due to wind-cold and dampness, arthralgia, rheumatism and rheumatoid and other diseases, proceed from the overall concept and treat based on syndrome differentiation. Based on the principle of treatment, a satisfactory curative effect can be achieved by using both internal and external treatment methods. Among them, hot ironing method, as a traditional common external treatment method of orthopedics in traditional Chinese medicine, has been recorded as early as in the Ming Dynasty medical book "Puji Fang". On the affected area, the drug effect can be applied to the local area with the help of heat to achieve the purpose of healing. As a traditional treatment method, the hot ironing method adopts many types of Chinese medicines, and there are also many prescriptions configured, each of which has its own advantages and disadvantages in performance and efficacy. On the basis of traditional prescriptions, combined with the theory and practice of traditional Chinese medicine, the orthopedic department with better curative effect is configured for the treatment of bruises, blood stasis, swelling and pain, muscle and bone pain, lumbago due to wind-cold and dampness, joint pain, rheumatism and rheumatoid diseases Hot compress medicine is the goal that the field of traditional Chinese medicine is constantly pursuing, and it is also a Chinese medicine topic in this field.
发明内容Contents of the invention
本发明的目的是提供一种治疗跌打损伤、瘀血肿痛、筋骨诸痛、风寒湿性腰痛、关节痛、风湿及类风湿类疾病等疾病的骨科热敷药。The purpose of the present invention is to provide a kind of orthopedic hot compress medicine for treating bruises, blood stasis, swelling and pain, pains in muscles and bones, lumbago due to wind-cold-dampness, arthralgia, rheumatism and rheumatoid diseases and the like.
为了达到上述目的,本发明总结了近百年来中医理论的审证求因、辨证施治的经验积累,结合传统经验方,按不同组分,不同剂量,并经反复筛选组分及临床实验,研制出本发明的配方,具体配方如下:一种骨科热敷药,由下列中药原料按重量份数混合后制备而成:In order to achieve the above-mentioned purpose, the present invention summarizes the accumulation of experience in examining syndromes and seeking causes and treating syndromes based on syndrome differentiation in the theory of traditional Chinese medicine in the past hundred years, combined with traditional empirical prescriptions, according to different components, different doses, and through repeated screening of components and clinical experiments, Developed the formula of the present invention, concrete formula is as follows: a kind of orthopedic hot compress medicine, is prepared by mixing the following Chinese medicine raw materials by weight:
伸筋草300g;透骨草300g;海桐皮150g;木瓜90g;防风150g,地枫150g;独活90g;赤芍150g;红花90g;骨碎补150g;急性子150g;川椒90g;乳香90g;白芷90g;川牛膝90g;桂枝150g;大青盐300g.300g Shenjincao; 300g Sperantosporum; 150g Pittodia bark; 90g papaya; 150g Fangfeng, 150g Difeng; 90g solitary life; 150g red peony root; 90g safflower; ; Baizhi 90g; Sichuan Achyranthes bidentata 90g; Guizhi 150g; Daqing salt 300g.
按上述配方经过传统中药粉末的制备方法,粉成粗粉,过二号筛,混合均匀,分8份,装无纺布袋,备用。Through the preparation method of traditional Chinese medicine powder according to the above formula, it is pulverized into coarse powder, passed through a No. 2 sieve, mixed evenly, divided into 8 parts, packed in non-woven bags, and set aside.
本发明在制备过程中,对于药材组分在投料前进行质量检查,使其质量符合《中国药典》等有关规定的质量标准;根据骨科热敷药的用法要求,需要将装入袋内的药蒸制,所以选择药材粉碎的程度要适中,实验表明,本发明采用二号药筛符合工艺要求。In the preparation process of the present invention, the quality inspection is carried out on the medicinal material components before feeding, so that their quality meets the quality standards stipulated in the "Chinese Pharmacopoeia" and other relevant regulations; system, so the degree of crushing the selected medicinal materials will be moderate, and experiments show that the present invention adopts No. 2 medicinal sieves to meet the technical requirements.
本发明根据骨科热敷药的理化性质,参照《中国药典》等有关规定,对本品进行性状、鉴别、检查、含量等测定,以保证药品安全有效,测定方法及结果如下:According to the physical and chemical properties of orthopedic hot compress medicine, the present invention refers to relevant regulations such as "Chinese Pharmacopoeia" to measure the properties, identification, inspection and content of this product, so as to ensure that the drug is safe and effective. The determination method and results are as follows:
1.性状本品为黄棕色药材粗粉;气香,味苦1. Properties This product is a yellow-brown coarse powder of medicinal materials; fragrant and bitter
2.鉴别2. Identification
2.1显微鉴别:取本品粉末,置显微镜下观察:花粉粒明显,呈圆球形或椭圆形,直径62-83um,萌发孔3个,外壁具有短刺及疣状突起(红花)。草酸钙簇晶圆簇状或类圆形;导管多为网纹,少螺纹;木栓细胞淡黄棕色,壁薄;淀粉粒较多,单粒圆球形或椭圆形(白芷)。2.1 Microscopic identification: Take the powder of this product and observe under a microscope: the pollen grains are obvious, spherical or oval, with a diameter of 62-83um, 3 germination holes, and short spines and verrucous protrusions (safflower) on the outer wall. Calcium oxalate clusters are clustered or round; the vessels are mostly reticulate and less threaded; the cork cells are light yellowish brown with thin walls; there are many starch grains, single spherical or oval (Angelica dahurica).
2.2薄层鉴别2.2 TLC identification
2.2.1赤芍药材的薄层鉴别取本品粉末5g,加乙醇20ml,超声处理30min,滤过,滤液蒸干,残渣加水20ml,用水饱和的正丁醇提取3次,每次20ml,合并正丁醇液,蒸干,残渣加乙醇2ml使溶解,作为供试品溶液。另取芍药苷对照品,加乙醇制成每1ml含2mg的溶液,作为对照品溶液。照薄层色谱法(中国药典2005年版一部附录VIB)试验,吸取上述两种溶液各5μL,分别点于同一硅胶G薄层板上,以三氯甲烷-乙酸乙酯-甲醇-甲酸(40∶5∶10∶0.2)为展开剂,展开,取出,晾干。喷以5%的香草醛硫酸溶液,加热至斑点显色清晰。供试品色谱中,在与对照品色谱相应的位置上,显相同的蓝紫色斑点。2.2.1 TLC identification of Radix Paeoniae Rubra, take 5g of this product powder, add 20ml of ethanol, ultrasonically treat for 30min, filter, evaporate the filtrate to dryness, add 20ml of water to the residue, extract 3 times with n-butanol saturated with water, 20ml each time, combine The n-butanol solution was evaporated to dryness, and the residue was dissolved by adding 2ml of ethanol as the test solution. Take another paeoniflorin reference substance, add ethanol to make a solution containing 2mg per 1ml, as the reference substance solution. According to the test of thin-layer chromatography (Appendix VIB, Chinese Pharmacopoeia 2005 Edition), draw 5 μL of each of the above two solutions, respectively spot on the same silica gel G thin-layer plate, and use chloroform-ethyl acetate-methanol-formic acid (40 : 5: 10: 0.2) as the developer, develop, take out, and dry. Spray with 5% vanillin sulfuric acid solution and heat until the spots are clear in color. In the chromatogram of the test product, at the position corresponding to the chromatogram of the reference product, the same blue-purple spots appear.
2.2.2桂枝药材的薄层鉴别取供试品粉术10g,加乙醇40ml,浸泡20min,时时振摇,滤过,滤液蒸干,残渣加乙醇1ml,作为供试品溶液。另取桂皮醛对照品,加乙醇制成每1ml含1uL的溶液,作为对照品溶液。照薄层色谱法(中国药典2005年版一部附录VIB)试验,吸取上述供试品溶液10μL,对照品溶液2μL分别点于同一硅胶G薄层板上,以石油醚(60-90℃)-乙酸乙酯(17∶3)为展开剂,展开,取出,晾干。喷以二硝基苯肼溶液。供试品色谱中,在与对照品色谱相应的位置上,显相同的橙黄色斑点。2.2.2 TLC identification of cinnamon twig medicinal materials Take 10g of the test sample powder, add 40ml of ethanol, soak for 20min, shake it from time to time, filter, evaporate the filtrate to dryness, add 1ml of ethanol to the residue, and use it as the test solution. Take another cinnamon aldehyde reference substance, add ethanol to make a solution containing 1uL per 1ml, as the reference substance solution. According to the thin-layer chromatography (Appendix VIB, Chinese Pharmacopoeia, 2005 edition), draw 10 μL of the above-mentioned test solution and 2 μL of the reference solution respectively on the same silica gel G thin-layer plate, and use petroleum ether (60-90°C)- Ethyl acetate (17:3) was used as the developer, developed, taken out, and dried in the air. Spray with dinitrophenylhydrazine solution. In the chromatogram of the test product, at the position corresponding to the chromatogram of the reference product, the same orange-yellow spots appear.
2.2.3红花药材的薄层鉴别取本品粉末5g,加80%丙酮溶液10ml,密塞,振摇15min,静置,吸取上清液,作为供试品溶液。另取红花对照药材0.5g,同法制成对照药材溶液。照薄层色谱法(中国药典2005年版一部附录VIB)试验,吸取上述供试品溶液15μL,对照品溶液5μL分别点于同一以羧甲基纤维素钠为黏合剂的硅胶H薄层板上,以乙酸乙酯-甲酸-水-甲醇(7∶2∶3∶0.4)为展开剂,展开,取出,晾干。供试品色谱中,在与对照药材色谱相应的位置上,显相同颜色的斑点。2.2.3 TLC identification of safflower medicinal materials Take 5g of this product powder, add 10ml of 80% acetone solution, seal it, shake it for 15min, let it stand still, absorb the supernatant, and use it as the test solution. Take another 0.5 g of safflower reference medicinal material, and make a reference medicinal material solution in the same way. According to the thin-layer chromatography (Appendix VIB of the Chinese Pharmacopoeia 2005 edition), draw 15 μL of the above-mentioned test solution and 5 μL of the reference solution respectively on the same silica gel H thin-layer plate with sodium carboxymethylcellulose as the binder. , using ethyl acetate-formic acid-water-methanol (7:2:3:0.4) as the developing solvent, develop, take out, and dry in the air. In the chromatogram of the test product, there are spots of the same color at the position corresponding to the chromatogram of the control medicinal material.
具体实施方式Detailed ways
本发明的具体配方由以下实施例详细说明:一种骨科热敷药,由下列中药原料按重量份数混合后制备而成:The specific formula of the present invention is described in detail by the following examples: a kind of orthopedic hot compress medicine is prepared by mixing the following traditional Chinese medicine raw materials in parts by weight:
伸筋草300g;透骨草300g;海桐皮150g;木瓜90g;防风150g,地枫150g;独活90g;赤芍150g;红花90g;骨碎补150g;急性子150g;川椒90g;乳香90g;白芷90g;川牛膝90g;桂枝150g;大青盐300g.300g Shenjincao; 300g Sperantosporum; 150g Pittodia bark; 90g papaya; 150g Fangfeng, 150g Difeng; 90g solitary life; 150g red peony root; 90g safflower; ; Baizhi 90g; Sichuan Achyranthes bidentata 90g; Guizhi 150g; Daqing salt 300g.
按上述配方经过传统中药粉末的制备方法,混合均匀,粉成粗粉,过二号筛,混合均匀,分8份,装无纺布袋,备用。According to the above formula, go through the preparation method of traditional Chinese medicine powder, mix evenly, pulverize into coarse powder, pass through No. 2 sieve, mix evenly, divide into 8 parts, pack in non-woven bags, and set aside.
使用方法:取其中两袋放入水盆内浸泡两分钟后放在蒸锅内加热蒸15分钟后,取出一袋药,稍微散发一下热气在不烫皮肤的情况下,放在患处热敷,不热后再放回锅内蒸,再取出另一袋药同样操作,反复数次(约一个小时)每日一至二次,连用七天为一个疗程。How to use: Take two of the bags and soak them in a water basin for two minutes, put them in a steamer and steam them for 15 minutes, take out one bag of medicine, let out a little heat, and put it on the affected area for hot compress without burning the skin. After heating, put it back into the pot to steam, then take out another bag of medicine and do the same, repeat several times (about an hour) once or twice a day, and use it continuously for seven days as a course of treatment.
实施例Example
病例均来自北京积水潭医院正骨科。The cases were all from the Department of Orthopedics, Beijing Jishuitan Hospital.
一.骨科热敷药治疗腰椎间盘突出症的临床病例1. Clinical cases of orthopedic hot compresses in the treatment of lumbar disc herniation
腰椎间盘突出症是骨科的一种常见病,以人体下腰部疼痛伴有一侧或双侧下肢疼痛、麻木为主要症状的疾病。Lumbar disc herniation is a common disease in orthopedics. It is a disease characterized by pain in the lower back of the human body accompanied by pain and numbness in one or both lower extremities.
以门诊就诊的腰椎间盘突出症患者57例为对象,参照《中医病症诊断疗效标准》纳入诊断标准:①有腰部外伤、慢性劳损或受寒湿史,大部分患者在发病前有慢性腰痛史。②腰痛向臀部及下肢放射,腹压增加时疼痛加重。③脊柱侧弯,腰生理弧度消失,病变部位椎旁有压痛,并向下肢放射,腰活动受限。④下肢受累神经支配区有感觉过敏或迟钝,病程长者可出现肌肉萎缩。直腿抬高或加强试验阳性,膝、跟腱反射减弱或消失,拇指背伸力减弱。⑤X线摄片检查:脊柱侧弯,腰生理前凸消失,病变椎间盘可能变窄,相邻边缘有骨赘增生。CT检查可显示椎间盘突出的部位及程度。Taking 57 outpatients with lumbar disc herniation as subjects, the diagnostic criteria were included in the "Diagnostic and Curative Criteria for Diseases of Traditional Chinese Medicine": ①Having a history of lumbar trauma, chronic strain, or exposure to cold and dampness, most of the patients had a history of chronic low back pain before the onset. ② Low back pain radiates to the buttocks and lower limbs, and the pain is aggravated when the abdominal pressure increases. ③Scoliosis, the physiological curvature of the waist disappears, there is tenderness beside the spine at the lesion site, and radiates to the lower extremities, and the waist movement is limited. ④There is hyperesthesia or dullness in the innervated areas of the affected lower limbs, and muscle atrophy may occur in the elderly with the course of the disease. The straight leg raising or strengthening test was positive, the knee and Achilles tendon reflexes were weakened or disappeared, and the dorsiflexion of the thumb was weakened. ⑤ X-ray film examination: scoliosis, lumbar lordosis disappears, diseased intervertebral disc may become narrow, and there is osteophyte hyperplasia on the adjacent edge. CT examination can show the location and degree of intervertebral disc herniation.
将骨科热敷药外敷,使用前将药袋用水浸泡两分钟,控干,放在蒸锅内加热蒸10分钟,放至温度不致烫皮肤时热敷患处,每日1次,每次1小时,15天为1疗程。Apply orthopedic hot compress medicine externally, soak the medicine bag in water for two minutes before use, control it to dry, put it in a steamer and steam it for 10 minutes, put it in a steamer until the temperature does not burn the skin, and apply heat to the affected part, once a day, 1 hour each time, 15 minutes One day is a course of treatment.
临床观察结果:在57例中,痊愈25例,显效32例,愈显率87.7%Clinical observation results: Among the 57 cases, 25 cases were cured, 32 cases were markedly effective, and the cure rate was 87.7%.
二、骨科热敷药治疗膝关节骨性关节炎的临床病例2. Clinical cases of orthopedic hot compresses in the treatment of knee osteoarthritis
膝关节骨性关节炎是骨伤科临床常见疾病,其病理特征是关节软骨发生原发或继发性改变和由此而导致的关节软骨变性、软化并逐渐消失,软骨下骨质改变,骨板层骨质硬化,随后出现软骨下及边缘骨赘形成,继发关节滑膜炎、关节囊挛缩、关节间隙狭窄,引起关节功能障碍等症状。Osteoarthritis of the knee joint is a common clinical disease in the Department of Orthopedics and Traumatology. Its pathological features are primary or secondary changes in articular cartilage and the resulting degeneration, softening and gradual disappearance of articular cartilage, changes in subchondral bone, bone Lamellar bone sclerosis, followed by subchondral and marginal osteophyte formation, secondary joint synovitis, joint capsule contracture, joint space narrowing, causing joint dysfunction and other symptoms.
选择64例膝关节骨性关节炎患者,观察腾药治疗膝关节骨性关节炎的临床疗效和放射学前后改变。参照《中药新药临床研究指导原则》诊断标准;A临床a.前月大多数日子有膝痛;b.关节活动时有骨响声;c.晨僵<30min;d.年龄大于或等于38岁;e.膝关节检查显示骨性肥大。存在a、b、c、d或a、b、c或a、d、e即可诊断。B临床及放射学a.前月大多数日子有膝痛;b.X线显示关节边缘骨赘;c.关节炎实验室检查符合骨性关节炎;d.年龄大于或等于40岁;e.晨僵<30min;f.关节活动时有骨响声。存在a、b或a、c、e、f或a、d、e、f即可诊断。A total of 64 patients with knee osteoarthritis were selected to observe the clinical efficacy and radiological changes of Teng Yao in the treatment of knee osteoarthritis. Refer to the diagnostic criteria in the "Guiding Principles of Clinical Research of New Chinese Medicines"; A. Clinical a. Knee pain on most days in the previous month; b. Bone sound when moving joints; c. Morning stiffness <30 minutes; d. Age greater than or equal to 38 years old; e. . Knee examination showed bony hypertrophy. The diagnosis can be made by the presence of a, b, c, d or a, b, c or a, d, e. B. Clinical and radiological a. Knee pain on most days in the previous month; b. X-ray showed osteophyte at the joint margin; c. Arthritis laboratory test consistent with osteoarthritis; d. Age greater than or equal to 40 years old; e. Morning stiffness < 30 minutes; f. There is a bone sound when the joint is moved. The diagnosis can be made by the presence of a, b or a, c, e, f or a, d, e, f.
将骨科热敷药外敷,使用前将药袋用水浸泡两分钟,控干,放在蒸锅内加热蒸15分钟,放至温度不致烫皮肤时热敷患处,每日1次,每次1小时,15天为1疗程。Apply orthopedic hot compress medicine externally, soak the medicine bag in water for two minutes before use, control it dry, heat and steam in a steamer for 15 minutes, put it in a steamer until the temperature does not burn the skin, and apply heat to the affected area, once a day, 1 hour each time, 15 minutes One day is a course of treatment.
临床观察结果:在64例中,显效49例,有效8例,总有效率为89.1%。Clinical observation results: Among the 64 cases, 49 cases were markedly effective, 8 cases were effective, and the total effective rate was 89.1%.
通过以上临床病例证明,本配方对治疗瘀血肿痛、筋骨诸痛、风寒湿性腰痛、节痛、风湿及类风湿等疾病具有显著疗效,本骨科热敷药的另外一个名称为骨科腾药。The above clinical cases prove that this formula has a significant curative effect on the treatment of blood stasis and swelling, muscle and bone pain, wind-cold-damp lumbago, arthralgia, rheumatism and rheumatoid and other diseases. Another name of this orthopedic hot compress is Orthopedics Teng Yao.
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Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104784318A (en) * | 2015-05-11 | 2015-07-22 | 原所茂 | Orthopedic hot compress medicine and preparation method and using method thereof |
CN105535295A (en) * | 2016-01-26 | 2016-05-04 | 王健军 | Blood circulation promoting and meridian obstruction removing hot compress salt for lumbar spondylosis and preparation method |
CN105687896A (en) * | 2016-01-26 | 2016-06-22 | 王健军 | Muscle-warming and cold-dispelling hot-applied salt and preparation method thereof |
CN106214884A (en) * | 2016-07-25 | 2016-12-14 | 麦敢连 | A kind of external medicated bag |
CN110237158A (en) * | 2019-06-28 | 2019-09-17 | 广西壮族自治区花红药业股份有限公司 | It is a kind of to rule the external application bone setting powder for treating rheumatic bone pain by law based on hot salt |
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