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CN103751560B - A kind of Chinese medicine composition for the treatment of insufficiency of the spleen fire type recurrent oral ulceration - Google Patents

A kind of Chinese medicine composition for the treatment of insufficiency of the spleen fire type recurrent oral ulceration Download PDF

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CN103751560B
CN103751560B CN201410053751.XA CN201410053751A CN103751560B CN 103751560 B CN103751560 B CN 103751560B CN 201410053751 A CN201410053751 A CN 201410053751A CN 103751560 B CN103751560 B CN 103751560B
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chinese medicine
insufficiency
medicine composition
radix
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CN103751560A (en
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赵秀华
刘海英
卢桂萍
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Liu Haiying
Lu Guiping
Zhao Xiuhua
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Abstract

Treat a Chinese medicine composition for insufficiency of the spleen fire type recurrent oral ulceration, this Chinese medicine composition is by native Iuba Equi, Dendrobium jenkinsii Wall ex Lindl., Chelonia mydas (Linnaeus), Radix Polygoni Multiflori, Ilex purpurea Hassk.[I.chinensis Sims, Herba Duchesneae Indicae, Bulbus Lilii, Radix Salviae Miltiorrhizae, and Radix Ophiopogonis, salty Depositum urinae preparatum is made.Clinical can be used for, treats insufficiency of the spleen fire type recurrent oral ulceration.

Description

A kind of Chinese medicine composition for the treatment of insufficiency of the spleen fire type recurrent oral ulceration
Technical field
The invention belongs to technical field of Chinese medicines, especially relate to a kind of Chinese medicine composition for the treatment of insufficiency of the spleen fire type recurrent oral ulceration.
Background technology
Recurrent oral ulceration is common frdquently encountered disease, and be the oral mucosa infective inflammation disease caused by various diseases, its cause of disease is comparatively complicated, with antibacterial, viral infection, immunologic hypofunction, inherited genetic factors, systemic disease and vitamin deficiency etc.
Kind or several factor relevant, individual variation is obvious, once form oral ulcer, scorching hot pain, feed water is limited, abnormal painful.The traditional Chinese medical science thinks that its pathogenesis is caused by damp-heat in the spleen and stomach, pathogenic fire derived from stagnation of liver-QI, YIN-fluid being insufficient, hyperactivity of deficient fire etc. mostly.Insufficiency of the spleen fire type recurrent oral ulceration is clinical normal with dizziness and tinnitus, soreness of the waist and knees, dysphoria with feverish sensation in the chest palms and soles, dry mouth and throat, or the recurrence of gynecologic menstrual aphtha, in oral cavity ulcer many in buccal, lingual surface, gums be upper and lower, the few or flower stripping of red tongue tongue, the symptoms such as thready and rapid pulse.Clinical Practice finds, Drug therapy of the present invention is insufficiency of the spleen, and fire type recurrent oral ulceration reaches good effect.
Summary of the invention
The object of the present invention is to provide that a kind of therapeutic effect is good, effective percentage is high, Chinese medicine composition to the insufficiency of the spleen fire type recurrent oral ulceration of the treatment of human non-toxic's side effect.
The object of the present invention is achieved like this, according to Chinese medical theory, utilizes the property of medicine of Chinese medicine uniqueness, adopt native Iuba Equi, Dendrobium jenkinsii Wall ex Lindl., Chelonia mydas (Linnaeus), Radix Polygoni Multiflori, Ilex purpurea Hassk.[I.chinensis Sims, Herba Duchesneae Indicae, Bulbus Lilii, Radix Salviae Miltiorrhizae, Radix Ophiopogonis, salty Depositum urinae preparatum is made, according to certain compatibility requirement, through being processed into.
Prepare Chinese medicine composition of the present invention to be made up of following raw material medicaments: native Iuba Equi 40-50 part, Dendrobium jenkinsii Wall ex Lindl. 30-40 part, Chelonia mydas (Linnaeus) 10-20 part, Radix Polygoni Multiflori 20-30 part, Ilex purpurea Hassk.[I.chinensis Sims 20-30 part, Herba Duchesneae Indicae 20-30 part, Bulbus Lilii 10-20 part, Radix Salviae Miltiorrhizae 10-20 part, Radix Ophiopogonis 10-20 part, salty Depositum urinae preparatum 10-20 part.
Optimum weight part of traditional Chinese medicinal composition raw materials of the present invention is: 45 parts, native Iuba Equi, Dendrobium jenkinsii Wall ex Lindl. 35 parts, Chelonia mydas (Linnaeus) 15 parts, Radix Polygoni Multiflori 25 parts, Ilex purpurea Hassk.[I.chinensis Sims 25 parts, Herba Duchesneae Indicae 25 parts, Bulbus Lilii 15 parts, Radix Salviae Miltiorrhizae 15 parts, Radix Ophiopogonis 15 parts, salty Depositum urinae preparatum 15 parts.
The pharmacological action of Chinese medicine of the present invention is as follows:
Soil Iuba Equi: sweet, sour, cold.Return lung, liver, large intestine channel.Nourishing YIN and clearing away heat, cooling blood for hemostasis.Clinical in deficiency of YIN hectic fever due to YIN-deficiency, hectic fever night sweat, pulmonary tuberculosis cough, heat in blood is spitted blood, and spitting of blood, has blood in stool, metrorrhagia, the diseases such as constipation and anuresis.
Dendrobium jenkinsii Wall ex Lindl.: sweet, light, cool.Attach to the lung and stomach meridians.Nourishing the lung to arrest cough, tonifying-Yin and nourishing-stomach.Clinical in cough due to lung-heat, pulmonary tuberculosis, asthma, dysentery, stomatitis, stomachache, the diseases such as infantile malnutrition.
Chelonia mydas (Linnaeus): sweet, salty, cold.Return liver, spleen, the heart, stomach warp.Nourishing YIN for suppressing the hyperactive YANG, nourishing blood and hemoslasis.Clinical in weakness due to chronic disease, row is thin weak, night sweat spontaneous perspiration, spits blood, metrorrhagia, the diseases such as leukopenia.
Radix Polygoni Multiflori: bitter, sweet, puckery, warm.Return liver, kidney channel.Nourishing the blood and yin, loosening bowel to relieve constipation, preventing the attack (or recurrence) of malaria, dispels the wind, removing toxic substances.Clinical in blood deficiency Light-headedness, cardiopalmus, insomnia, the soreness of the waist and knees of the hepatic and renal YIN deficiency, early whitening of beard and hair, tinnitus, seminal emission, dryness of the intestine constipation, chronic malaria body is empty, rubella pruritus, carbuncle sore, scrofula, the diseases such as hemorrhoid.
Ilex purpurea Hassk.[I.chinensis Sims: bitter, puckery, cool.Heat-clearing and toxic substances removing, promoting tissue regeneration and ulcer healing, promoting blood circulation and hemostasis.For cough due to lung-heat, laryngopharynx swelling and pain, dysentery, diarrhoea, biliary tract infection, urinary tract infection, angina pectoris, burn and scald, pyretic toxicity carbuncle, ulcer of the lower limb, leprelcosis, eczema, chilblain, chaps, thromboangiitis obliterans, the diseases such as traumatic hemorrhage.
Herba Duchesneae Indicae: sweet, bitter, cold.Return lung, liver, large intestine channel.Heat-clearing and toxic substances removing, dissipating blood stasis for subsidence of swelling, cooling blood for hemostasis.Calentura, infantile convulsion, cough, spits blood, laryngopharynx swelling and pain, dysentery, carbuncle, furuncle, snake bite and insect sting, burn and scald, flu, jaundice, conjunctival congestion, aphtha, mumps, furuncle and phyma, metrorrhagia, menoxenia, treating swelling and pain by traumatic injury.
Bulbus Lilii: sweet, micro-hardship, to be slightly cold.GUIXIN, lung meridian.Nourishing YIN and moistening the lung, clearing away heart-fire for tranquillization.Clinical in deficiency of YIN chronic cough, sputum mixed with blood, in the calentura later stage, fidgets due to deficiency is palpitated with fear, insomnia and dreamful sleep, carbuncle, the diseases such as eczema.
Radix Salviae Miltiorrhizae: bitter, be slightly cold.GUIXIN, Liver Channel.Promoting blood flow to regulate menstruation, removing heat from blood eliminating carbuncle, calms the nerves.For the ambition of blood stasis, epigastric pain Ji lumps in the chest and abdomen, rheumatic arthralgia, skin infection carbuncle etc.
Salty Depositum urinae preparatum: salty, cold, nontoxic.GUIXIN, kidney, lung meridian.YIN nourishing arresting seminal emission, clearing heart fire.Clinical in osteopyrexia and fever, cough due to consumptive disease, seminal emission, leucorrhea with red and white discharge, summer-heat is vexed, aphtha, the diseases such as laryngopharynx swelling and pain.
Motherland's medical science is thought, primary disease is many caused by insufficiency of the spleen hyperactivity of fire, is referred to as " aphtha ", " aphtha ", and how because of the heresy of affection due to external wind and heat, oral cavity is unclean, and damaged in mouth, evil poison enters interior relevant, and the unsuccessful heart spleen that undermines of temperament and interest all causes insufficiency of the spleen fire type recurrent oral ulceration.After being mainly in fatigue, taste are deficient, and spleen is the lucid yang sending up not, and functional activity of QI being not smooth then sends out ulcer, the light depression of skin ulcer complexion, periphery turns white, time light time heavy, spiritlessness and weakness, deficiency of QI with disinclination to talk, lip white is light, time have low grade fever, extremity are not warm, and dysfunction of the spleen in transportation is anorexia then, few Tianjin of xerostomia and do not like drink.The present invention's soil Iuba Equi nourishing YIN and clearing away heat, for monarch drug, Dendrobium jenkinsii Wall ex Lindl. tonifying-Yin and nourishing-stomach, Chelonia mydas (Linnaeus) YIN nourishing, nourishes blood, for ministerial drug, Radix Polygoni Multiflori nourishes blood, YIN nourishing, removing toxic substances, Ilex purpurea Hassk.[I.chinensis Sims heat-clearing and toxic substances removing, promoting tissue regeneration and ulcer healing, Herba Duchesneae Indicae heat-clearing and toxic substances removing, dissipating blood stasis for subsidence of swelling, Bulbus Lilii yin nourishing, clear away heart-fire, calm the nerves, Radix Salviae Miltiorrhizae is invigorated blood circulation, removing heat from blood, to calm the nerves, salty Depositum urinae preparatum YIN nourishing, clear away heart-fire, pathogenic fire reducing.Compatibility reaches nourishing YIN to lower pathogenic fire, nourishing blood to tranquillize the mind jointly, effect of removing toxic substances sore, promotes that topical ulcers heals very soon, reaches the object for the treatment of insufficiency of the spleen fire type recurrent oral ulceration.
Chinese medicine composition of the present invention is used in 2006 to 2013 the routine patients of clinical observation insufficiency of the spleen fire type recurrent oral ulceration disease 69, and clinical report is as follows:
1, physical data
In 69 routine patients, women 39 example, male 30 example, at minimum 20 years old of age, maximum 64 years old, the course of disease was many at 3 months to 2 years, 34.3 years old mean age.
2, diagnostic criteria
With reference to " Chinese medical disease Standardization of diagnosis and curative effect ":
1. occur ulcer that is single or several diameter 3 ~ 5mm with oral mucosa, scorching hot pain is cardinal symptom;
2. onset is very fast, healing in general about 7 days, if down here, then the course of disease extends, normal easily recurrence more;
3. examination of mouth: stomatocace is comparatively shown shallow, circular or oval, quantity 1 ~ 2 at least, more than 10 at most, surface has faint yellow secretions to adhere to, and ulcer surrounding mucosa is mostly congested.
Insufficiency of the spleen fire type recurrent oral ulceration clinical symptoms: dizziness and tinnitus, soreness of the waist and knees, dysphoria with feverish sensation in the chest palms and soles, dry mouth and throat, or the recurrence of gynecologic menstrual aphtha, in oral cavity ulcer many in buccal, lingual surface, gums be upper and lower, the few or flower stripping of red tongue tongue, thready and rapid pulse.
3, Therapeutic Method
3.1 prescriptions: native Iuba Equi 45g, Dendrobium jenkinsii Wall ex Lindl. 35g, Chelonia mydas (Linnaeus) 15g, Radix Polygoni Multiflori 25g, Ilex purpurea Hassk.[I.chinensis Sims 25g, Herba Duchesneae Indicae 25g, Bulbus Lilii 15g, Radix Salviae Miltiorrhizae 15g, Radix Ophiopogonis 15g, salty Depositum urinae preparatum 15g.
3.2 preparation methoies: said medicine routinely technique makes decoction.
3.3 instructions of taking: each 1 dose, every day 2 times 5 days was 1 course for the treatment of.
4, therapeutic outcome:
4.1 with reference to " Chinese medical disease Standardization of diagnosis and curative effect ":
Cure: oral ulcer heals, local is without sense of discomfort;
Take a turn for the better: although have recurrence during oral ulcer, quantity reduces, and degree alleviates;
Do not heal: oral ulcer symptom and ulcer are without significant change.
4.2 results: in 69 routine patients, cure 45 examples (65.2%), 19 examples that take a turn for the better (27.5%), and do not heal 5 examples (7.3%), and total effective rate is 92.7%.
5, model case
5.1 grandsons, man, 36 years old, oral erosion more than 3 years, recurrent exerbation, rose one after another, once takes Chinese and western drugs and intramuscular injection interferon etc., and the state of an illness is without being clearly better.See time medical that there is the ulcer of two Semen Viciae fabae sample sizes on tongue body both sides, intermediate recess, surface is covered by white pod membrane, and in oral cavity, both sides also sporadically appear multiple aphtha, and surface is greyish white, and ambient color is light red.Dizziness and tinnitus, soreness of the waist and knees, red tongue, thready and rapid pulse.Take the Chinese medicine composition that the present invention treats insufficiency of the spleen fire type recurrent oral ulceration to treat, after treating 1 course for the treatment of, patient mental is good, and ulcer improves gradually, takes medicine continuously 1 course for the treatment of afterwards, and recovery from illness, follows up a case by regular visits to and do not recur for 1 year again.
5.2 weeks certain, female, 42 years old.Oral cavity is rotten to the corn, causalgia often, and rise one after another, recurrent exerbation more than 2 years, be recurrent oral ulceration through hospital diagnosis, Chinese and western medicine multi-treatment is not imitated.Dizziness and tinnitus, soreness of the waist and knees, dysphoria with feverish sensation in the chest palms and soles, dry mouth and throat, oliguria with yellow urine, red tongue, yellow and thin fur, thready and rapid pulse.The tip of the tongue, limit have several pieces of beans size ulcer surfaces, and there is a larger ulcer at buccal mucosa place, and color is red, the pain touched.Taken the Chinese medicine composition that the present invention treats insufficiency of the spleen fire type recurrent oral ulceration, 4 courses for the treatment of, disease obtains recovery from illness, follows up a case by regular visits to and does not recur for 1 year again.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is further illustrated, and this embodiment following does not only limit the present invention for illustration of the present invention.
Embodiment 1, a kind of Chinese medicine composition for the treatment of insufficiency of the spleen fire type recurrent oral ulceration, it is made up of following raw material medicaments: native Iuba Equi 40g, Dendrobium jenkinsii Wall ex Lindl. 30g, Chelonia mydas (Linnaeus) 10g, Radix Polygoni Multiflori 20g, Ilex purpurea Hassk.[I.chinensis Sims 20g, Herba Duchesneae Indicae 20g, Bulbus Lilii 10g, Radix Salviae Miltiorrhizae 10g, Radix Ophiopogonis 10g, salty Depositum urinae preparatum 10g.
Embodiment 2, a kind of Chinese medicine composition for the treatment of insufficiency of the spleen fire type recurrent oral ulceration, it is made up of following raw material medicaments: native Iuba Equi 45g, Dendrobium jenkinsii Wall ex Lindl. 35g, Chelonia mydas (Linnaeus) 15g, Radix Polygoni Multiflori 25g, Ilex purpurea Hassk.[I.chinensis Sims 25g, Herba Duchesneae Indicae 25g, Bulbus Lilii 15g, Radix Salviae Miltiorrhizae 15g, Radix Ophiopogonis 15g, salty Depositum urinae preparatum 15g.
Embodiment 3, a kind of Chinese medicine composition for the treatment of insufficiency of the spleen fire type recurrent oral ulceration, it is made up of following raw material medicaments: native Iuba Equi 50g, Dendrobium jenkinsii Wall ex Lindl. 40g, Chelonia mydas (Linnaeus) 20g, Radix Polygoni Multiflori 30g, Ilex purpurea Hassk.[I.chinensis Sims 30g, Herba Duchesneae Indicae 30g, Bulbus Lilii 20g, Radix Salviae Miltiorrhizae 20g, Radix Ophiopogonis 20g, salty Depositum urinae preparatum 20g.

Claims (2)

1. treat a Chinese medicine composition for insufficiency of the spleen fire type recurrent oral ulceration, it is characterized in that being made up of following crude drug:
Soil Iuba Equi 40-50 part, Dendrobium jenkinsii Wall ex Lindl. 30-40 part, Chelonia mydas (Linnaeus) 10-20 part, Radix Polygoni Multiflori 20-30 part, Ilex purpurea Hassk.[I.chinensis Sims 20-30 part, Herba Duchesneae Indicae 20-30 part, Bulbus Lilii 10-20 part, Radix Salviae Miltiorrhizae 10-20 part, Radix Ophiopogonis 10-20 part, salty Depositum urinae preparatum 10-20 part.
2. Chinese medicine composition according to claim 1, is characterized in that being made up of following crude drug:
Soil 45 parts, Iuba Equi, Dendrobium jenkinsii Wall ex Lindl. 35 parts, Chelonia mydas (Linnaeus) 15 parts, Radix Polygoni Multiflori 25 parts, Ilex purpurea Hassk.[I.chinensis Sims 25 parts, Herba Duchesneae Indicae 25 parts, Bulbus Lilii 15 parts, Radix Salviae Miltiorrhizae 15 parts, Radix Ophiopogonis 15 parts, salty Depositum urinae preparatum 15 parts.
CN201410053751.XA 2014-02-18 2014-02-18 A kind of Chinese medicine composition for the treatment of insufficiency of the spleen fire type recurrent oral ulceration Expired - Fee Related CN103751560B (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1682909A (en) * 2005-03-14 2005-10-19 张晓帅 Chinese medicine composition for treating recurrent ulcer of mouth
CN1814208A (en) * 2005-12-02 2006-08-09 钟祖光 Oral Chinese medicine for treating and preventing recurrence of uecerative stomatitis

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1682909A (en) * 2005-03-14 2005-10-19 张晓帅 Chinese medicine composition for treating recurrent ulcer of mouth
CN1814208A (en) * 2005-12-02 2006-08-09 钟祖光 Oral Chinese medicine for treating and preventing recurrence of uecerative stomatitis

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