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CN103736297A - Sample adding device - Google Patents

Sample adding device Download PDF

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Publication number
CN103736297A
CN103736297A CN201210392241.6A CN201210392241A CN103736297A CN 103736297 A CN103736297 A CN 103736297A CN 201210392241 A CN201210392241 A CN 201210392241A CN 103736297 A CN103736297 A CN 103736297A
Authority
CN
China
Prior art keywords
base plate
adding device
sample
sample adding
circumferential wall
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201210392241.6A
Other languages
Chinese (zh)
Inventor
沈金辉
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
QIFUKANG DRUG RESEARCH AND DEVELOPMENT (SUZHOU) Co Ltd
Original Assignee
QIFUKANG DRUG RESEARCH AND DEVELOPMENT (SUZHOU) Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by QIFUKANG DRUG RESEARCH AND DEVELOPMENT (SUZHOU) Co Ltd filed Critical QIFUKANG DRUG RESEARCH AND DEVELOPMENT (SUZHOU) Co Ltd
Priority to CN201210392241.6A priority Critical patent/CN103736297A/en
Publication of CN103736297A publication Critical patent/CN103736297A/en
Pending legal-status Critical Current

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Abstract

The invention discloses a sample adding device in a cup shape. The sample adding device comprises circumferential wall and a base plate. The circumferential wall is provided with a contacting surface corresponding to a standard ground mouth of a chromatographic column. The external surface of the circumferential wall is provided with at least one pressure-reducing groove penetrating through the surface and is evenly provided with at least two guiding grooves. The base plate is at the middle and lower part of the contacting surface. The periphery of the base plate is evenly provided with at least two guiding holes communicated with the guiding grooves. By utilization of principles of fluid dynamics, a sample can be added more uniformly, washing for the filling materials on the column bed is reduced, influences on the uniformity are reduced, and the separation effects are enhanced.

Description

A kind of sample adding device
Technical field
The present invention relates to Chemical Decomposition field, relate in particular to a kind of normal pressure, low pressure chromatographic column sample adding device.
Background technology
At biochemical field, liquid chromatogram isolation technics is the most common technique of compound separation purifying, the low pressure that wherein basic separation method is conventional, normal pressure column chromatography method, usually inhomogeneous because the problem of application of sample causes post bed fillers to be washed, chromatographic isolation weak effect.Even if veteran experimenter, use dropper to drip to be also difficult to guarantee post bed fillers is not washed and all the time smooth evenly.
Summary of the invention
Defect in view of above-mentioned prior art exists, the object of the invention is to propose a kind of sample adding device, utilizes principle of hydrodynamics, reduces the inhomogeneity impact of application of sample link coupled columns bed fillers.
Object of the present invention will be achieved by the following technical programs:
A kind of sample adding device, cup-shaped, comprise perisporium and base plate, described perisporium is provided with a contact-making surface corresponding with chromatographic column standard frosted mouth, described contact-making surface outer surface is provided with at least one and runs through surperficial decompression groove, is evenly provided with at least two guiding gutters, and described base plate is positioned at contact-making surface middle and lower part, described base plate is evenly provided with at least two pod apertures around, and described pod apertures is communicated with described guiding gutter.When sample solution adds fashionablely, sample can slowly flow to post bed along chromatographic column interface and post jamb, and decompression groove communicates with the external world, balance chromatographic column inner and outer air pressure.
Outstanding effect of the present invention is:
Utilize fluid dynamic principle, make application of sample more even, reduced washing away of coupled columns bed fillers, reduced inhomogeneity impact, improved separating effect.
Below just accompanying drawing in conjunction with the embodiments, is described in further detail the specific embodiment of the present invention, so that technical solution of the present invention is easier to understand, grasp.
Accompanying drawing explanation
Fig. 1 is the structural representation of sample adding device.
The specific embodiment
Embodiment:
A kind of sample adding device of the present embodiment, as shown in Figure 1, cup-shaped, comprise perisporium 1 and base plate 2, described perisporium 1 is provided with a contact-making surface 3 corresponding with chromatographic column standard frosted mouth, and contact-making surface 3 outer surfaces are provided with at least one and run through surperficial decompression groove 4, evenly be provided with at least two guiding gutters 5, base plate 2 is positioned at contact-making surface 3 middle and lower parts, and base plate is evenly provided with at least two pod apertures 6 around, and pod apertures 6 is communicated with guiding gutter 5.When sample solution adds fashionablely, sample can slowly flow to post bed along chromatographic column interface and post jamb, and decompression groove 4 communicates with the external world, balance chromatographic column inner and outer air pressure.
The present embodiment utilizes fluid dynamic principle, makes application of sample more even, has reduced washing away of coupled columns bed fillers, has reduced inhomogeneity impact, has improved separating effect.
The present invention still has numerous embodiments, and all employing equivalents or equivalent transformation and all technical schemes of forming, within all dropping on protection scope of the present invention.

Claims (1)

1. a sample adding device, it is characterized in that: cup-shaped, comprise perisporium and base plate, described perisporium is provided with a contact-making surface corresponding with chromatographic column standard frosted mouth, described contact-making surface outer surface is provided with at least one and runs through surperficial decompression groove, is evenly provided with at least two guiding gutters, and described base plate is positioned at contact-making surface middle and lower part, described base plate is evenly provided with at least two pod apertures around, and described pod apertures is communicated with described guiding gutter.
CN201210392241.6A 2012-10-17 2012-10-17 Sample adding device Pending CN103736297A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201210392241.6A CN103736297A (en) 2012-10-17 2012-10-17 Sample adding device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201210392241.6A CN103736297A (en) 2012-10-17 2012-10-17 Sample adding device

Publications (1)

Publication Number Publication Date
CN103736297A true CN103736297A (en) 2014-04-23

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN201210392241.6A Pending CN103736297A (en) 2012-10-17 2012-10-17 Sample adding device

Country Status (1)

Country Link
CN (1) CN103736297A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114669082A (en) * 2022-03-28 2022-06-28 利穗科技(苏州)有限公司 A kind of chromatographic system for radial, tangential flow bottom of chromatographic column and its combined use

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4341635A (en) * 1980-12-16 1982-07-27 Helena Laboratories Corporation Microchromatographic column and method
CN201988225U (en) * 2011-03-28 2011-09-28 赤峰市云淞科技发展有限责任公司 Chromatographic column
US20120103886A1 (en) * 2010-10-28 2012-05-03 BIA Separations d.o.o Sample distribution device for distribution of samples in liquid chromatographs
CN202315412U (en) * 2011-11-11 2012-07-11 济南大学 Constant-pressure automatic liquid-adding chromatography device

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4341635A (en) * 1980-12-16 1982-07-27 Helena Laboratories Corporation Microchromatographic column and method
US20120103886A1 (en) * 2010-10-28 2012-05-03 BIA Separations d.o.o Sample distribution device for distribution of samples in liquid chromatographs
CN201988225U (en) * 2011-03-28 2011-09-28 赤峰市云淞科技发展有限责任公司 Chromatographic column
CN202315412U (en) * 2011-11-11 2012-07-11 济南大学 Constant-pressure automatic liquid-adding chromatography device

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114669082A (en) * 2022-03-28 2022-06-28 利穗科技(苏州)有限公司 A kind of chromatographic system for radial, tangential flow bottom of chromatographic column and its combined use

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Addressee: Qifukang Drug Research and Development (Suzhou) Co., Ltd.

Document name: Notification of Publication and of Entering the Substantive Examination Stage of the Application for Invention

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Application publication date: 20140423