CN103732124A - Multi-spot laser surgical probe using faceted optical elements - Google Patents
Multi-spot laser surgical probe using faceted optical elements Download PDFInfo
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- A61B18/22—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibre; Couplings or hand-pieces therefor
- A61B2018/2255—Optical elements at the distal end of probe tips
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- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/008—Methods or devices for eye surgery using laser
- A61F2009/00861—Methods or devices for eye surgery using laser adapted for treatment at a particular location
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Abstract
在本发明的特定实施例中,一种光学外科探头包括配置为光学耦合到光源的手持件和位于手持件的远端的套管。探头还包括在手持件内的至少一个光导。光导配置为将来自光源的光束传输到手持件的远端。探头还包括位于套管中的多光斑生成器,多光斑生成器包括分面光学粘合剂,分面光学粘合剂具有与光导的远端隔开的分面端表面。分面端表面包括倾斜于光束的路径的至少一个面。在一些实施例中,探头还包括位于光导的远端的高传导率套圈。在其他实施例中,套管由透明材料形成。
In a particular embodiment of the invention, an optical surgical probe includes a handpiece configured to optically couple to a light source and a cannula at a distal end of the handpiece. The probe also includes at least one light guide within the handpiece. The light guide is configured to transmit the light beam from the light source to the distal end of the handpiece. The probe also includes a multi-spot generator located in the cannula, the multi-spot generator including a faceted optical adhesive having a faceted end surface spaced from the distal end of the light guide. The facet end surface includes at least one facet oblique to the path of the light beam. In some embodiments, the probe also includes a high conductivity ferrule at the distal end of the light guide. In other embodiments, the sleeve is formed from a transparent material.
Description
相关申请related application
本申请要求于2011年8月9日提交的美国临时申请序列号61/521,447的优先权,其内容通过引用并入本文。本申请涉及共同未决的美国专利申请序列号12/959,533,其于2010年12月3日提交并且与本申请共同转让。This application claims priority to US Provisional Application Serial No. 61/521,447, filed August 9, 2011, the contents of which are incorporated herein by reference. This application is related to co-pending US Patent Application Serial No. 12/959,533, filed December 3, 2010 and commonly assigned with this application.
技术领域technical field
本发明涉及光学外科探头,更具体地,涉及使用分面(faceted)光学元件的多光斑激光外科探头。The present invention relates to optical surgical probes and, more particularly, to multi-spot laser surgical probes using faceted optics.
背景技术Background technique
光学外科探头将光输送到用于各种应用的外科区域。在一些应用中,将光输送到手术区域中的多个斑点是有用的。例如,在视网膜组织的泛视网膜光凝中,可期望的是将激光输送到多个斑点,以便减少泛视网膜光凝程序的时间。各种技术已经被用来针对多光斑图案产生多个光束。例如,一种方案使用衍射分束器元件,以将入射光束划分为被耦合到多个光纤的多个光斑,该多个光纤将该多个光斑输送到视网膜。但是,也可期望具有多光斑生成器,其可以布置在光学外科探头的远端以更容易地从单一输入光束产生多个光斑,以使得多光斑生成器可以更容易地与现有的激光源一起使用,而不需要额外的部件将激光外科探头与源对准。Optical surgical probes deliver light to the surgical field for various applications. In some applications, it is useful to deliver light to multiple spots in the surgical field. For example, in pan-retinal photocoagulation of retinal tissue, it may be desirable to deliver laser light to multiple spots in order to reduce the time of the pan-retinal photocoagulation procedure. Various techniques have been used to generate multiple beams for multi-spot patterns. For example, one approach uses a diffractive beam splitter element to split an incident light beam into multiple spots that are coupled to multiple optical fibers that deliver the multiple spots to the retina. However, it may also be desirable to have a multi-spot generator that can be placed at the distal end of the optical surgical probe to more easily generate multiple spots from a single input beam so that the multi-spot generator can be more easily integrated with existing laser sources Used together without the need for additional parts to align the laser surgical probe with the source.
在光学外科探头的远端使用衍射分束器元件时会出现困难。作为一个示例,衍射分束器元件产生大量更高的衍射级,并且虽然这些衍射级在光强度上比主光斑图案相对较低,但是就其影响而言并不总是可以忽略它们。作为另一示例,衍射元件在不同折射率介质中可能表现不同。例如,如果衍射分束器元件被布置到不同于空气的介质中,如盐溶液或油中,则衍射分束器元件的微观表面浮雕结构的凹陷部分可被填充折射率不同于空气的材料,这会毁坏光斑图案。作为又一个示例,光斑之间的间隔可能对于不同的波长而改变,这在瞄准光束具有特定颜色而治疗光束具有不同颜色时可能会产生问题。最后,衍射元件常常很昂贵并且难以制造,并且在衍射元件必须被构造为适配小区域(诸如用于23号(23-gauge)或更小的外科器械的外科探头的远端尖端)的情况下更加如此。因此,仍然需要一种光学外科探头,其可以使用在外科探头的远端处的光学元件在目标区域产生多个光斑。Difficulties arise when using diffractive beam splitter elements at the distal end of an optical surgical probe. As an example, diffractive beam splitter elements produce a large number of higher diffraction orders, and although these are relatively lower in light intensity than the main spot pattern, they are not always negligible in terms of their impact. As another example, diffractive elements may behave differently in different refractive index media. For example, if the diffractive beam splitter element is arranged in a medium different from air, such as a saline solution or oil, the recessed parts of the microscopic surface relief structure of the diffractive beam splitter element can be filled with a material with a different refractive index than air, This will destroy the speckle pattern. As yet another example, the spacing between spots may vary for different wavelengths, which may be problematic when the aiming beam is of a certain color and the treatment beam is of a different color. Finally, diffractive elements are often expensive and difficult to manufacture, and where the diffractive element must be configured to fit a small area such as the distal tip of a surgical probe for 23-gauge or smaller surgical instruments The next is even more so. Therefore, there remains a need for an optical surgical probe that can generate multiple spots of light at a target area using optical elements at the distal end of the surgical probe.
发明内容Contents of the invention
本发明的特定实施例提供一种热鲁棒的光学外科探头,其包括具有分面光学粘合剂元件的多光斑生成器。在本发明的特定实施例中,一种光学外科探头包括配置为光学耦合到光源的手持件和位于手持件的远端的套管。探头还包括位于手持件内的至少一个光导。光导配置为将来自光源的光束传输到手持件的远端。探头还包括位于套管中的多光斑生成器,多光斑生成器包括分面光学粘合剂,分面光学粘合剂具有与光导的远端隔开的分面端表面。分面端表面包括倾斜于光束的路径的至少一个面。在一些实施例中,探头还包括位于光导的远端的高传导率套圈。在其他实施例中,套管由透明材料形成。Certain embodiments of the present invention provide a thermally robust optical surgical probe comprising a multi-spot generator with a faceted optical adhesive element. In a particular embodiment of the invention, an optical surgical probe includes a handpiece configured to optically couple to a light source and a cannula at a distal end of the handpiece. The probe also includes at least one light guide within the handpiece. The light guide is configured to transmit the light beam from the light source to the distal end of the handpiece. The probe also includes a multi-spot generator located in the cannula, the multi-spot generator including a faceted optical adhesive having a faceted end surface spaced from the distal end of the light guide. The facet end surface includes at least one facet oblique to the path of the light beam. In some embodiments, the probe also includes a high conductivity ferrule at the distal end of the light guide. In other embodiments, the sleeve is formed from a transparent material.
参照附图以及附图和权利要求的以下描述,本发明的其他目的、特征和优点将变得明显。Other objects, features and advantages of the present invention will become apparent with reference to the drawings and the following description of the drawings and claims.
附图说明Description of drawings
图1示出根据本发明特定实施例的具有高热传导性套圈的多光斑生成器;Figure 1 illustrates a multi-spot generator with a high thermal conductivity ferrule according to certain embodiments of the invention;
图2示出根据本发明特定实施例的具有透明套管的多光斑生成器;以及Figure 2 illustrates a multi-spot generator with a transparent sleeve according to certain embodiments of the invention; and
图3示出根据本发明替代实施例的具有透明套管的多光斑生成器。Figure 3 shows a multi-spot generator with a transparent sleeve according to an alternative embodiment of the invention.
具体实施方式Detailed ways
与本申请共同转让的、于2010年12月3日提交的共同未决的美国申请序列号12/959,533描述了一种使用分面光学粘合剂的多光斑光学外科探头。本发明的各种实施例提供附加的特征,以促进分面光学粘合剂在光学外科探头中的使用。特别是,本发明的某些实施例提供使用分面光学粘合剂的热鲁棒光学外科探头。如下面详细描述的,本发明的特定实施例包括附加的特征,以减少“热斑”在外科探头中发生的可能性,“热斑”会导致分面光学粘合剂或粘合套圈和套管的粘合剂劣化和/或失效。Co-pending US Application Serial No. 12/959,533, filed December 3, 2010, commonly assigned with the present application, describes a multi-spot optical surgical probe using a faceted optical adhesive. Various embodiments of the present invention provide additional features to facilitate the use of faceted optical adhesives in optical surgical probes. In particular, certain embodiments of the present invention provide thermally robust optical surgical probes using faceted optical adhesives. As described in detail below, certain embodiments of the present invention include additional features to reduce the likelihood of "hot spots" occurring in surgical probes that can result in faceted optical adhesives or bonded ferrules and Adhesive deterioration and/or failure of sleeve.
在本发明的某些实施例中,位于探头的远端内的套圈被修改以提高其从探头的远端尖端传导热的能力。第一修改是将材料从通常使用的、低热传导率的不锈钢改变为具有高得多的热传导率的材料,例如铜或银。套圈的材料不必是生物相容的,因为它在物理上与探头的外部隔离。这允许选择非生物相容性材料,诸如具有比任何可用的生物相容性材料高得多的热传导率的铜或银。较高的热传导率更有效地传导热量远离探头的远端。第二修改是添加远端侧屏蔽体到圆柱形套圈,其防止从粘合剂面反射的光照明套管并且被套管吸收。相反,反射光照明高热传导率套圈并且基本上由高热传导率套圈吸收,该高热传导率套圈高效地传导热量远离探头的远端。In certain embodiments of the invention, the ferrule located within the distal end of the probe is modified to improve its ability to conduct heat from the distal tip of the probe. The first modification is to change the material from the commonly used, low thermal conductivity stainless steel to a material with much higher thermal conductivity, such as copper or silver. The material of the ferrule does not have to be biocompatible since it is physically isolated from the exterior of the probe. This allows the selection of non-biocompatible materials such as copper or silver which have a much higher thermal conductivity than any available biocompatible material. Higher thermal conductivity conducts heat more efficiently away from the distal end of the probe. A second modification is the addition of a distal side shield to the cylindrical ferrule, which prevents light reflected from the adhesive face from illuminating the sleeve and being absorbed by the sleeve. Instead, reflected light illuminates and is substantially absorbed by the high thermal conductivity ferrule, which efficiently conducts heat away from the distal end of the probe.
在本发明的替代实施例中,以透明套管替换吸收套管,透明套管将来自粘合剂面的反射光透射到套管外部的周围区域中。这导致探头的远端的温度显著降低。因为指向外科医生的高强度透射光可能与他观看视网膜发生干扰,各种手段可用于阻止或消除这个光,包括在透明套管外侧上的反射、漫射或半透明的层和在透明套管外侧并且物理上与其间隔绝缘空气间隙的不透明圆柱形套管。这一不透明套管不必由高热传导性材料制成,而是可以由刚性和强的材料(诸如不锈钢)形成,其对于探头的远端提供附加的结构强度。In an alternative embodiment of the invention, the absorbing sleeve is replaced by a transparent sleeve which transmits the reflected light from the adhesive face into the surrounding area outside of the sleeve. This results in a significant drop in temperature at the distal end of the probe. Because the high-intensity transmitted light directed at the surgeon may interfere with his viewing retina, various means are available to block or eliminate this light, including reflective, diffuse or translucent layers on the outside of the transparent sleeve and An opaque cylindrical sleeve outside and physically separated from it by an insulating air gap. This opaque sleeve need not be made of a high thermal conductivity material, but may be formed of a rigid and strong material such as stainless steel, which provides additional structural strength to the distal end of the probe.
图1示出根据本发明特定实施例的适于布置在光学外科探头的远端的多光斑生成器100。在所描绘的实施例中,具有诸如蓝宝石球透镜的球透镜106的分面光学粘合剂104位于套管108内。保持光纤112的高传导率套圈110位于套管108内。光纤112输送来自照明源(未示出)的诸如激光的光。Figure 1 illustrates a
高热传导率套圈110(在下文中称为“高传导率套圈”)由热传导率明显高于通常在光学外科探头中使用的不锈钢材料(其通常是大约15W/m-K)的材料形成。对于本说明书的目的,“高传导率”指的是具有超过100W/m-K的热传导率的材料。合适的示例包括铜(372W/m-K的传导率)、标准银(410W/m-K)或纯银(427W/m-K)。因为高传导率套圈110由分面光学粘合剂104封装在套管108内,高传导率套圈110不必由生物相容性材料制成,这允许考虑通常不用于光学外科探头中的高传导率材料。High thermal conductivity ferrule 110 (hereinafter "high conductivity ferrule") is formed of a material having a thermal conductivity significantly higher than stainless steel materials typically used in optical surgical probes, which are typically about 15 W/m-K. For the purposes of this specification, "high conductivity" refers to materials having a thermal conductivity in excess of 100 W/m-K. Suitable examples include copper (372W/m-K conductivity), standard silver (410W/m-K) or pure silver (427W/m-K). Because the high-
高传导率套圈110包括自光纤112向远端延伸的侧屏蔽体114。侧屏蔽体114被取向为接收从分面光学粘合剂104的面反射的光。虽然来自分面光学粘合剂104的反射在能量上比入射光束相对较低(入射能量的大约5%),但是这样的反射仍然可能在套管108上产生“热斑”。假如套管108通常由不锈钢或其他相对传导不良且反射性不高的材料形成,这会导致激光能量被吸收,从而造成过量的热积累在分面光学粘合剂104附近或将套圈110接合到套管114的粘合剂(未示出)附近的可能性。这会降低光学外科探头的性能。侧屏蔽体114拦截反射光束,以防止它们到达套管,并且由于套圈110的材料为高传导性的,通过在套圈110吸收反射光束而产生的任何热量被迅速地消散,从而防止套圈110的平衡温度显著升高。The high-
图2示出根据本发明的热鲁棒多光斑生成器的替代实施例。在所描绘的实施例中,套管108由透明材料形成。该材料优选是生物相容性的,但如果不是,外表面套管108也可被涂覆或处理,以提高生物相容性。透明套管108允许反射光穿过套管108,以避免形成热斑。在特定实施例中,套管108是漫射性的,以使得逃出的光不会形成可能分散外科医生注意力的可见光光斑。例如,套管108的表面可以由半透明材料制成,可以是化学或机械磨砂(如通过刮擦或酸蚀刻),或者可以涂覆有漫射涂层。在替代实施例中,套管108是透明的,但由反射涂层(诸如银)包围。反射涂层防止光进入外科医生的视野,同时仍将光反射离开分面光学粘合剂104,从而允许热量容易传导离开尖端。银或反射涂层的外表面可进行氧化或涂覆,以提高生物相容性。Figure 2 shows an alternative embodiment of a thermally robust multi-spot generator according to the invention. In the depicted embodiment,
图3示出透明套管108的替代实施例。在所描绘的实施例中,不透明外套管120围绕透明套管108。不透明外套管120可以由传统的生物相容性材料形成,并且其优选为相对吸收性的,但是它不必是高传导性的。外套管120与透明套管108通过空气间隙隔开。空气间隙提供透明套管108之间的热绝缘,并且透明套管108也可以由如玻璃的绝缘材料形成。任何产生于外套管120中的热量都可以传导到探头的其他部分或包围外套管120的生物材料中。外套管120与分面光学粘合剂104之间的热绝缘减少了过量的热累积在分面光学粘合剂104附近的可能性。FIG. 3 shows an alternative embodiment of the
在本文中通过示例说明了本发明,并且本领域普通技术人员可以进行各种修改。虽然详细说明了本发明,但应理解,在不偏离本发明要求保护的范围的情况下,可以作出各种改变、替换和变更。The present invention has been illustrated herein by way of example, and various modifications will occur to those skilled in the art. Although the present invention has been described in detail, it should be understood that various changes, substitutions and alterations could be made hereto without departing from the scope of the present invention.
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