A kind of thrombus elastic force measuring device
Technical field
The present invention relates to clinical examination technical field, more particularly, relate to a kind of thrombus elastic force measuring device.
Background technology
Thrombus elastic force analyser is a kind of extracorporeal diagnostic instrument, by blood sample coagulation or monitoring and the analysis of solidifying rear course of dissolution, assists clinician to make accurate evaluation to clinical patient Coagulability.Blood coagulation assessment is for clinical patient situation is made to effective prediction, such as the occurrence risk of thrombosis in the art of postoperative hemorrhage, cardiopulmonary surgery, organ transplant, trauma operation or in post-operative course.
At present, thrombus elastic force analyser mainly comprises test cup and the elastic force measuring mechanism that is arranged on test cup top; Wherein, test cup is used for holding blood sample and detects reagent, and it is provided with the hollow circular cylinder of rim of a cup for top; Elastic force measuring mechanism has elastic yarn and the vertical pin that is arranged on elastic yarn below and is connected with elastic yarn, and the bottom of the pin that hangs down is connected with coupling column, and this coupling column is arranged in the cup chamber of test cup, has the gap that holds blood sample between coupling column and test cup.
When test, first in the gap between coupling column and test cup, add blood sample and detect reagent, then making test cup rotate, when blood is liquid state, test cup does not produce acting force to coupling column, after blood generation is solidified, test cup and coupling column produce coupling, and test cup is coupled to rotating force on coupling column, coupling column and then drive elastic yarn reverse, the size of this rotating force is definite by the angle of elastic yarn, and describes record, thereby has realized the monitoring of blood sample coagulation and analysis.
But, in above-mentioned thrombus elastic force analyser, because the coupling column of elastic force measuring mechanism is arranged in the cup chamber of test cup, the cup chamber of test cup is coupled post and occupies, cause most of rim of a cup to be blocked, so can only be from the gap application of sample between coupling column and test cup, adding mouth is narrow, is not easy to application of sample; When the sample arm that is provided with sample needle due to utilization carries out application of sample, sample arm conventionally moves with swing arm mode and moves above test cup in XYZ mode with sample needle, and the elastic force measuring mechanism of this thrombus elastic force analyser is positioned at the top of test cup, block the round operation required space of the required sample arm of robotization application of sample, and then cannot realize robotization application of sample; Therefore can only adopt manual mode that blood sample and reagent are added along the gap between coupling column and test cup with sample injector, waste of manpower, causes thrombus elastic force analyser to realize semi-automation, and work efficiency is extremely low.The tertiary hospitals of take is example, and approximately there are 15-25 semi-automatic instruments in each hospital, needs artificial reagent adding and blood sample when operator uses these instruments, operates very loaded down with trivial detailsly, and workload is very large.
In sum, how to expand adding mouth, so that realize robotization application of sample, and then reduce operator's workload, be current those skilled in the art technical matterss urgently to be resolved hurrily.
Summary of the invention
In view of this, the object of the present invention is to provide a kind of thrombus elastic force measuring device, to expand adding mouth, and then be convenient to realize robotization application of sample, reduce operator's workload.
In order to achieve the above object, the invention provides following technical scheme:
A thrombus elastic force measuring device, comprising:
For holding the test cup of blood sample and detection reagent;
Glass stand, described test cup can swing and be suspended on described glass stand;
The drive unit that drives described test cup to swing around described glass stand;
After blood clotting, can be of coupled connections with described test cup, and produce the coupling piece of the bonding force that stops described test cup swing, described coupling piece is arranged on described glass stand, and is arranged in the cup chamber of described test cup;
The elastic force measuring mechanism that obtains the elastic force feature of the blood clotting in described test cup by detecting bonding force that described test cup is subject to, described elastic force measuring mechanism is arranged on described test cup below.
Preferably, above-mentioned thrombus elastic force measuring device also comprises that described automatic sample pin is positioned at the rim of a cup top of described test cup for add the automatic sample pin of blood sample and detection reagent in described test cup.
Preferably, in above-mentioned thrombus elastic force measuring device, the motor that described drive unit is reciprocating rotation, the pivot center of described motor is parallel with the axis of oscillation of described test cup.
Preferably, in above-mentioned thrombus elastic force measuring device, described motor passes to described test cup by shift fork by oscillatory forces, and the bottom of described test cup has the orienting lug that is arranged in described shift fork.
Preferably, in above-mentioned thrombus elastic force measuring device, described orienting lug is the bar blocks of extending along the direction of described axis of oscillation.
Preferably, in above-mentioned thrombus elastic force measuring device, described elastic force measuring mechanism comprises:
The coupling block being fixedly connected with the rotation axis of described motor;
Be fixed on the torsion torque sensor on described coupling block;
The elastic torsion silk that passes to described torsion torque sensor for the bonding force that described test cup is subject to, described elastic torsion silk is connected between described torsion torque sensor and described shift fork.
Preferably, in above-mentioned thrombus elastic force measuring device, described test cup is a plurality of, and on described glass stand, be provided with a plurality of for the installation portion of described test cup is installed, described installation portion along the axis of oscillation of described test cup arrange and with the corresponding setting one by one of described test cup.
Preferably, in above-mentioned thrombus elastic force measuring device, the end face of described installation portion has along described axis of oscillation extension and coaxial the first suspension groove and the second suspension groove, the outside of the tip edge of described test cup is respectively arranged with the first suspension strut and the second suspension strut, described the first suspension strut is positioned at described the first suspension groove swingably, and described the second suspension strut is positioned at described the second suspension groove swingably.
Preferably, in above-mentioned thrombus elastic force measuring device, described coupling piece and described glass stand are integral type structure by injection mo(u)lding, and described coupling piece stretches into the bottom in described test cup centre position.
Preferably, above-mentioned thrombus elastic force measuring device also comprises fixed head, and described glass stand is fixed on described fixed head.
From above-mentioned technical scheme, can find out, thrombus elastic force measuring device provided by the invention comprises test cup, glass stand, drive unit, coupling piece and elastic force measuring mechanism; Wherein, test cup is used for holding blood sample and detects reagent, and can swing and be suspended on glass stand; Drive unit is used for driving test cup to swing around glass stand; Coupling piece can be of coupled connections with test cup after blood clotting, and produces the bonding force that stops test cup to swing, and this coupling piece is arranged on glass stand and is arranged in the cup chamber of test cup; Elastic force measuring mechanism obtains the elastic force feature of the blood clotting in test cup by the bonding force that detects above-mentioned test cup and be subject to, and is arranged on the below of test cup.
The present invention, when test, first adds blood sample and detects reagent in test cup, then by drive unit, drives test cup to swing; When blood is liquid state, coupling piece can not exert an influence to the swing of test cup; When blood solidifies (being thrombosis), coupling piece can produce coupling to test cup, because coupling piece maintains static, so blood clotting can stop test cup to swing, then the resistance that the present invention is subject to by elastic force measuring mechanism detection test cup is bonding force namely, thereby the elastic force feature of the blood clotting in acquisition test cup (thrombus), and the process of setting of blood clotting and set strength, elastic stage are measured in the mode of electric signal, thereby realized the monitoring of blood sample coagulation and analysis.
The elastic force measuring mechanism that is arranged on test cup below due to utilization of the present invention is measured the resistance that test cup is subject to when swinging, and then realizes thrombus bullet force measurement.Owing to there is not restraining mass in the rim of a cup of test cup, expanded adding mouth, and the top of test cup has the required space of the round operation of the required sample needle of robotization application of sample, and then be convenient to realize robotization application of sample, can utilize in use sample needle automatic sample to substitute artificial, and then reduce operator's workload.
Accompanying drawing explanation
In order to be illustrated more clearly in the embodiment of the present invention or technical scheme of the prior art, to the accompanying drawing of required use in embodiment or description of the Prior Art be briefly described below, apparently, accompanying drawing in the following describes is some embodiments of the present invention, for those of ordinary skills, do not paying under the prerequisite of creative work, can also obtain according to these accompanying drawings other accompanying drawing.
Fig. 1 is the structural representation of the thrombus elastic force measuring device that provides of the embodiment of the present invention;
Fig. 2 is that the test cup that the embodiment of the present invention provides is suspended on the vertical view on glass stand;
Fig. 3 is the test cup of the embodiment of the present invention cut-open view along A-A line in Fig. 2 during to left swing;
Fig. 4 is the test cup of embodiment of the present invention cut-open view along A-A line in Fig. 2 while putting to the right;
Fig. 5 is the cut-open view along B-B line in Fig. 2;
Fig. 6 is the cut-open view along C-C line in Fig. 5;
Fig. 7 is the structural representation of the test cup that provides of the embodiment of the present invention;
Fig. 8 is the structural representation of the glass stand that provides of the embodiment of the present invention.
Embodiment
The embodiment of the present invention provides a kind of thrombus elastic force measuring device, has expanded adding mouth, and then is convenient to realize robotization application of sample, reduces operator's workload.
For making object, technical scheme and the advantage of the embodiment of the present invention clearer, below in conjunction with the accompanying drawing in the embodiment of the present invention, technical scheme in the embodiment of the present invention is clearly and completely described, obviously, described embodiment is the present invention's part embodiment, rather than whole embodiment.Embodiment based in the present invention, those of ordinary skills, not making the every other embodiment obtaining under creative work prerequisite, belong to the scope of protection of the invention.
Please refer to accompanying drawing 1-8, the thrombus elastic force measuring device that the embodiment of the present invention provides comprises test cup 2, glass stand 1, drive unit, coupling piece 3 and elastic force measuring mechanism; Wherein, test cup 2 is for holding blood sample and detecting reagent, and can swing and be suspended on glass stand 1; Drive unit is used for driving test cup 2 to swing around glass stand 1; Coupling piece 3 can be of coupled connections with test cup 2 after blood clotting, and produces the bonding force that stops test cup 2 to swing, and this coupling piece 3 is arranged on glass stand 1 and is arranged in the cup chamber of test cup 2; Elastic force measuring mechanism obtains the elastic force feature of the blood clotting in test cup 2 by the bonding force that detects above-mentioned test cup 2 and be subject to, and is arranged on the below of test cup 2.It should be explained that, coupling of the present invention refer to due to solidifying of blood make fixing coupling piece 3 and the test cup 2 that swings around glass stand 1 between the adhesion that produces.
The present invention, when test, first adds blood sample and detects reagent in test cup 2, then by drive unit, drives test cup 2 to swing; When blood is liquid state, coupling piece 3 can not exert an influence to the swing of test cup 2; When blood solidifies (being thrombosis), coupling piece 3 can produce coupling to test cup 2, because coupling piece 3 maintains static, so blood clotting can stop test cup 2 to swing, then the resistance that the present invention is subject to by elastic force measuring mechanism detection test cup 2 is bonding force namely, thereby obtain the elastic force feature of the blood clotting (thrombus) in test cup 2, and the process of setting of blood clotting and set strength, elastic stage are measured in the mode of electric signal, thereby realized the monitoring of blood sample coagulation and analysis.
The elastic force measuring mechanism that is arranged on test cup 2 belows due to utilization of the present invention is measured the resistance that test cup 2 is subject to when swinging, and then realizes thrombus bullet force measurement.Owing to there is not restraining mass in the rim of a cup of test cup 2, expanded adding mouth, and the top of test cup 2 has the required space of the round operation of the required sample needle of robotization application of sample, and then be convenient to realize robotization application of sample, can utilize in use sample needle automatic sample to substitute artificial, and then reduce operator's workload.
In the present invention's one specific embodiment, thrombus elastic force measuring device also comprises that this automatic sample pin 4 is positioned at the rim of a cup top of test cup 2 for add the automatic sample pin 4 of blood sample and detection reagent in test cup 2.The present invention is distinguished sample and reagent draw blood sample and detects reagent from sample area and the reagent area of instrument by automatic sample pin 4, then be automatically added to test cup 2, realized robotization application of sample, and then realized the robotization sample test of thrombus elastic force measuring device, improve to greatest extent clinical detection efficiency, saved manpower simultaneously.And hospital can only be used a thrombus elastic force measuring device, has reduced input cost.
In the present invention's one specific embodiment, drive unit is preferably the motor 8 of reciprocating rotation, and the pivot center of motor 8 is parallel with the axis of oscillation of test cup 2.The present invention drives test cup 2 to swing by making motor 8 carry out reciprocating rotation, and control accuracy is higher, thereby can control preferably the swing of test cup 2.Interchangeable, above-mentioned drive unit can also be rotary cylinder or electromagnet apparatus etc., and the effect swinging to reach same driving test cup 2, introduces no longer one by one at this.
Further, in technical scheme, motor 8 passes to test cup 2 by shift fork 6 by oscillatory forces, and the bottom of test cup 2 has the orienting lug 21 that is arranged in shift fork 6.The present embodiment drives shift fork 6 to swing by motor 8, by shift fork 6, oscillatory forces is delivered on the orienting lug 21 of test cup 2, then drives test cup 2 to swing.
Adopt shift fork 6 to carry out transmission of power and there is good stability, and this shift fork 6 can avoid motor 8 to be directly connected with test cup 2, the impact while having reduced motor 8 rotating force conversion, test cup 2 having been caused, and then reduced the vibration that thrombus elastic force measuring device produces when work, thereby reduced the damage to test cup 2.Certainly, motor 8 also can directly be connected with test cup 2, as the driving shaft of motor 8 is fixedly connected with the orienting lug 21 of test cup 2, and then drives orienting lug 21 to swing.
In order further to optimize technique scheme, orienting lug 21 is the bar blocks of extending along the direction of axis of oscillation.Now bar blocks can coordinate better with shift fork 6, the power of motor 8 passes through shift fork 6 Transmit evenlies on bar blocks, make bar blocks along stress equalization in the direction of axis of oscillation, thereby avoid test cup 2 to rotate, and then guaranteed swinging of test cup 2.
In the present invention's one specific embodiment, elastic force measuring mechanism comprises: the coupling block 9 being fixedly connected with the rotation axis of motor 8; Be fixed on the torsion torque sensor 7 on coupling block 9; The elastic torsion silk 10 that passes to torsion torque sensor 7 for the bonding force that test cup 2 is subject to, this elastic torsion silk 10 is connected between torsion torque sensor 7 and shift fork 6.
As shown in Figure 1, the top of elastic torsion silk 10 is connected with shift fork 6, and bottom is arranged on coupling block 9.When test, first utilize automatic sample pin 4 to add blood sample and detect reagent in test cup 2, then make motor 8 drive coupling blocks 9 with and on elastic torsion silk 10 swing, and by shift fork 6, oscillatory forces is delivered in test cup 2, and then drives test cup 2 to swing.When blood solidifies, the grumeleuse of blood can stop test cup 2 to swing, shift fork 6 passes to this resistance on torsion torque sensor 7 by elastic torsion silk 10, the coupling resistance being subject to by measuring test cup 2 by torsion torque sensor 7, and then measure process of setting, set strength and the elastic stage of blood clot.
Above-mentioned test cup 2 is preferably a plurality of, and on glass stand 1, is provided with a plurality of installation portions 13 for installation testing cup 2, this installation portion 13 along the axis of oscillation of test cup 2 arrange and with test cup 2 corresponding setting one by one.As shown in Fig. 2, Fig. 5 and Fig. 8, the present invention has a plurality of test cups 2, each test cup 2 can be used different detection reagent, and then can carry out different test events, so the thrombus elastic force measuring device of the present embodiment can detect multiple test event simultaneously, and while needing to clean after one of them test cup 2 is used, can utilize other test cup 2 to proceed test, the continuity that has guaranteed test, has improved testing efficiency.Certainly, above-mentioned test cup also can be 1 or 2, should select according to actual testing requirement the number of test cup.
In the present invention's one specific embodiment, the end face of the installation portion 13 of glass stand 1 has along axis of oscillation extension and coaxial the first suspension groove 11 and the second suspension groove 12, as shown in Figure 8; The outside of the tip edge of test cup 2 is respectively arranged with the first suspension strut 22 and the second suspension strut 23, as shown in Figure 7; The first suspension strut 22 is positioned at swingably the first suspension groove 11, the second suspension struts 23 and is positioned at swingably the second suspension groove 12, as shown in Fig. 2-6.In said structure, the first suspension strut 22 and the second suspension strut 23 are coaxial, and the central axis conllinear of both central axis and two suspension grooves, and the axis of oscillation of all test cups 2 is suspension groove and the total central axis of suspension strut.
The present invention is by being suspended on the suspension strut in test cup 2 respectively on two suspension grooves of glass stand 1, test cup 2 central axis around the first suspension strut 22 and the second suspension strut 23 when test is swung, having realized test cup 2 swings and is arranged on glass stand 1, simple in structure, be convenient to manufacture, be convenient to test cup 2 simultaneously and be assemblied in installation portion 13.
It will be understood by those skilled in the art that, above-mentioned glass stand 1 can also be connected by other structures with test cup 2, as suspended axle being set on glass stand 1, and the suppending hole penetrating for suspended axle is set in the corresponding position of test cup 2, to reach same, test cup 2 can be swung be arranged on the effect on glass stand 1, at this, introduce no longer one by one.
Preferably, in the thrombus elastic force measuring device that above-described embodiment provides, coupling piece 3 is integral type structure with glass stand 1 by injection mo(u)lding.The present invention is integrated coupling piece 3 and glass stand 1, coupling piece 3 stretches in glass chamber, has improved the strength of joint of coupling piece 3 with glass stand 1, and then has improved the steadiness of coupling piece 3, avoid touching because of test cup 2 situation of coupling piece 3 swings that cause, guaranteed the accuracy of test result.
Simultaneously, when test cup 2 swings, touch coupling piece 3, the present invention makes coupling piece 3 stretch into the bottom in test cup 2 centre positions, is convenient to like this blood sample and detects reagent be full of the gap between coupling piece 3 and test cup 2, reduce the addition of blood sample, be convenient to test.
In order further to optimize technique scheme, above-mentioned thrombus elastic force measuring device also comprises fixed head 5, and glass stand 1 is fixed on fixed head 5, as shown in Figure 1.Above-mentioned fixed head 5, for glass stand 1 is fixed, has improved the stability of glass stand 1, and then fixed coupling sheet 3 better, avoids the swing that in test process, coupling piece 3 occurs.
In this instructions, each embodiment adopts the mode of going forward one by one to describe, and each embodiment stresses is the difference with other embodiment, between each embodiment identical similar part mutually referring to.
Above-mentioned explanation to the disclosed embodiments, makes professional and technical personnel in the field can realize or use the present invention.To the multiple modification of these embodiment, will be apparent for those skilled in the art, General Principle as defined herein can, in the situation that not departing from the spirit or scope of the present invention, realize in other embodiments.Therefore, the present invention will can not be restricted to these embodiment shown in this article, but will meet the widest scope consistent with principle disclosed herein and features of novelty.