CN103617346B - Postpartum hemorrhage pre-warning system based on epidemiology, biochemistry and placental factors - Google Patents

Abstract

The postpartum hemorrhage early warning system based on epidemiological, biochemical and placental factors belongs to the field of obstetrical medical devices, and is characterized in that it is a postpartum hemorrhage early warning system composed of a computer, LED light-emitting diode panel and an alarm. The computer is equipped with: Information import of maternal epidemiology, biochemical and placental factors, array switch of risk factors for postpartum hemorrhage in pregnant women, calculation of logistic regression value of postpartum hemorrhage in pregnant women and risk alarm of postpartum hemorrhage in pregnant women, in the form of logistic regression The risk coefficient converts the input risk value into the risk value of postpartum hemorrhage to display the postpartum risk status of pregnant women, and whether the 19 risk factors input through the LED light-emitting diode panel are converted into the risk value of a single factor and its radius The relative important value represented by the distance is transformed into luminous flux and then an alarm is given. The present invention can estimate the risk value of postpartum hemorrhage in pregnant women in real time and give an early warning.

Description

Early warning system for postpartum hemorrhage based on epidemiological, biochemical and placental factors

technical field

The invention relates to the field of medical devices, in particular to an early warning system for postpartum hemorrhage based on epidemiological, biochemical and placental factors.

Background technique

Obstetric hemorrhage is the most common and serious complication in obstetrics, and it is a serious disease that threatens the life safety of pregnant women. However, the vast majority of postpartum hemorrhage can be avoided. Therefore, how to effectively prevent postpartum hemorrhage has become the focus of perinatal health care.

The cause of postpartum hemorrhage is mainly uterine atony: systemic factors are due to maternal physical weakness, chronic and acute medical history, delayed labor, mental stress and use of sedatives or anesthetics, etc. Local factors are caused by polyhydramnios, multiple pregnancy, macrosomia, etc. Uterine overexpansion, multiparous women, repeated pregnancy and childbirth; uterine dysplasia, such as polygonal uterus, double uterus, etc.; There are many reasons for placental retention, etc., and finally soft birth canal injury, abnormal blood coagulation, uterine inversion, etc. are all causes of postpartum hemorrhage.

Some scholars judge the risk of postpartum hemorrhage through high-risk dynamic assessment. This scoring method mainly judges whether placental factors and individual epidemiological factors exceed the standard range. As long as any of them exceeds the standard, the patient needs to be highly valued and observed. Although this method has certain accuracy and pertinence, the scope of evaluation is not comprehensive.

At present, many postpartum hemorrhages for pregnant women are more of a solution after the disease occurs, and few pregnant women are evaluated and paid attention to and observed during pregnancy. Moreover, according to statistical methods and a large number of literature readings, postpartum hemorrhage involves a number of high-risk factors, including maternal epidemiological factors, biochemical factors, and placental factors. The current evaluation methods are mostly one-sided and single, and cannot combine the accurate analysis of the risk of postpartum hemorrhage of pregnant women with the ease of analysis and implementation by medical staff. and the risk of morbidity, take certain measures to prevent and improve the adverse pregnancy outcome as much as possible.

Contents of the invention

The object of the present invention is to design a postpartum hemorrhage early warning system based on epidemiological, biochemical and placental factors. The device involves epidemiological factors, biochemical factors and placental factors. Logistic regression values, finally expressing postpartum hemorrhage risk by numerical value, topographic map and buzzer.

The present invention is characterized in that it is a dangerous value calculation and early warning system for real-time monitoring and early warning of the risk of postpartum hemorrhage in pregnant women, which is composed of a computer, an LED light-emitting diode panel and a buzzer alarm, wherein:

The computer 1 is equipped with: an information import module 11 of epidemiology, biochemical and placental factors of pregnant women, an array switch module 12 of risk factors for postpartum hemorrhage in pregnant women, a logic regression value calculation module for the risk of postpartum hemorrhage in pregnant women 13 and the onset risk alarm module 14 of maternal postpartum hemorrhage, in which:

The information import module 11 of epidemiology, biochemical and placental factors of pregnant women includes: the information import module 111 of epidemiological and biochemical factors of pregnant women and the information import module 112 of placental factors of pregnant women, wherein:

Maternal epidemiology and biochemical factor information import module 111 is provided with: a total of 13 epidemiological information input items marked with x' ₁ ~ x' ₁₃ , and the order of the 13 epidemiological information is: age , pregnancy body mass index, multiple pregnancy, family history of hypertension, history of adverse pregnancy, history of abdominal surgery, hypertensive disorder of pregnancy, first trimester bleeding, macrosomia, polyhydramnios, uterine ovarian fibroids, threatened premature labor and pelvic soft birth canal exception, where:

Age, when greater than or equal to the critical value A ₁ , input information x' ₁ =1, when the age is less than the critical value A ₁ , x' ₁ =0, A ₁ =35 years old,

When the body mass index during pregnancy is greater than or equal to the critical value A ₂ , input information x' ₂ =1; when the age is less than the critical value A ₂ , x' ₂ =0, A ₂ =25,

The remaining 11 pieces of information are represented by x' ₃ ~ x' ₁₃ in sequence, among them, when any piece of information exists, the corresponding epidemiological input signal value is 1, and when it does not exist, the corresponding epidemiological input signal value is 0; There are also two biochemical information input items marked with x' ₁₄ ~ x' ₁₅ , including: hemoglobin information x' ₁₄ and platelet count information x' ₁₅ , wherein:

When the hemoglobin information x' ₁₄ is less than or equal to the critical value A ₃ , the corresponding epidemiological input signal value is 1, and when it is greater than the critical value A ₃ , the epidemiological input signal value is 0, A ₃ =100c1, c1 is the concentration unit, expressed in grams per liter,

When the platelet count information x' ₁₅ is less than the critical value A ₄ , the corresponding epidemiological input signal value is 1, and when it is greater than or equal to the critical value A ₄ , the epidemiological input signal value is 0, A ₄ = 100×10 ⁹ pieces/L;

The information import module 112 of maternal placental factors is provided with: input items of 4 placental factor information marked with x' ₁₆ ~ x' ₁₉ , and the 4 placental factor information is expressed in sequence as: placenta previa information x' _16. Placental abruption information x' ₁₇ , placental retention information x' ₁₈ and placental adhesion information x' ₁₉ , wherein: when any one of the placental factor information exists, its input signal value is 1, and if it does not exist, the input signal value is 0,

The information import module 11 of the epidemiology, biochemical and placental factors of the pregnant and lying-in women, when any input signal in the input signal value _{x'i exists, the corresponding output signal x"i value} is 1, if not exist , the corresponding output signal x” _i value is 0, i=1,2,3…i,…,19,

The array switch module 12 of risk factors for postpartum hemorrhage in pregnant women includes: an array switch module 121 of epidemiological and biochemical factors for the risk of postpartum hemorrhage in pregnant women and an array switch module 122 of placental factors for the risk of postpartum hemorrhage in pregnant women, in:

The epidemiological and biochemical factor array switch module 121 of the risk of maternal postpartum hemorrhage is provided with: 13 epidemiological information input terminals respectively connected with 13 of the maternal epidemiological and biochemical factor information import module 111 Two maternal epidemiological information output terminals are connected, input epidemiological information x" _i , i=1, 2...13; two biochemical information input terminals are respectively connected with the maternal epidemiological and biochemical factor information The two biochemical information output terminals of the import module 111 are connected, input biochemical factor information x" _i , i=14,15,

The placental factor array switch module 122 of the risk of maternal postpartum hemorrhage is provided with: four input terminals of the placental factor information, respectively connected to the corresponding output terminals of the information import module 112 of the maternal placental factor, input Placental factor information x" _i , i=16,17,18,19,

The array switch module 121 of the epidemiological and biochemical factors of the risk of postpartum hemorrhage in pregnant women is provided with an output terminal corresponding to the input 15 pieces of information, and outputs 15 risk factor values of epidemiological and biochemical factors x ₁ ~ x ₁₅ , when there is an input signal value x” _i , x” _i = 1, then the output corresponding risk factor value x ₁ ～ x ₁₅ takes a value of 1, when there is no input signal x” _i = 0, then the output The risk factor value x _i takes the value of 0, i=1,2...15,

The placental factor array switch module 122 of the risk of postpartum hemorrhage in pregnant women is provided with an output terminal corresponding to the input information of 4 placental factors, and outputs 4 placental risk factor values x ₁₆ ~ x ₁₉ , when there is an input signal x When " _i ", x" _i = 1, then the output corresponding risk factor value x _i is 1, if there is no input signal, x" _i = 0, then the output corresponding risk factor value x _i =0, i =16,17,18,19,

The 19 output signals x _i , i=1, 2...19, are called risk factor values,

The logistic regression value calculation module 13 of the incidence risk of postpartum hemorrhage in pregnant women is provided with: an epidemiological risk value p _epidemiology generation module 131, a biochemical factor risk value p _biochemistry generation module 132, a placental factor risk value p _placenta generation module 133 and a puerpera Postpartum hemorrhage risk value p _PPH generation module 134, wherein,

The epidemiology risk value p _epidemiology generating module 131 is provided with 13 epidemiological risk factor value input terminals, and the epidemiology in the module 121 is switched with the array of epidemiological and biochemical factors of the incidence risk of maternal postpartum hemorrhage The 13 output terminals of the risk factor value are connected, input x ₁ ~ x ₁₃ , a total of 13 epidemiological risk factor values _xi , when _xi exists, _xi = 1, the output is the epidemiological risk value X _i , X _i = 1, if _xi does not exist, _xi = 0, epidemiological risk value Xi = 0, _i = 1, 2, 3...i,..., 13, also set: epidemiological risk coefficient E _j , j=1,2,3...j,...,13, corresponding to the X _i along the serial number, multiplied to obtain 13 _{epidemiological} risk values E _j X _i , the output is epidemic = ∑ _{i, j} E _j X _i , i=j=1,2...13,

The biochemical risk value p _biochemistry generation module 132 is provided with: 2 biochemical risk factor value input terminals, and the array switch module 121 of the biochemical risk factor value of the epidemiological and biochemical factors of the maternal postpartum hemorrhage risk The corresponding two output terminals in x _i are connected, input x ₁₄ ~ x ₁₅ , a total of two biochemical risk factors x _i values, when x _i exists, x _i =1, the output is biochemical risk value X _i , Xi ₌ 1. If x _i does not exist, x _i = 0, biochemical risk value Xi ₌ 0, i = 14, 15, and also set: biochemical risk coefficients B ₁ and B ₂ , following the serial numbers and the said X ₁₄ , X ₁₅ corresponds to each other, multiplying them to get 2 biochemical hazard values B ₁ X ₁₄ and B ₂ X ₁₅ , output p _biochemistry = B ₁ X ₁₄ +B ₂ X ₁₅ ,

The placenta factor risk value p _placenta generating module 133 is provided with: 4 placenta risk factor value input terminals, and 4 output terminals of the placenta risk factor value in the placenta factor array switching module 122 of the maternal postpartum hemorrhage risk Connected, input x ₁₆ ~ x ₁₉ a total of 4 placental risk factors x _i values, when x _i exists, x _i = 1, the output is placental risk value X _i , Xi = 1, if x _i does not exist, x _{i i} = 0, placental risk value X _i = 0, i = 16, 17, 18, 19, also set: placental risk coefficients P ₁ , P ₂ , P ₃ , P ₄ , following the serial numbers and the X ₁₆ , X ₁₇ , X ₁₈ , and X ₁₉ correspond to each other, and multiply them to obtain four placental risk values P ₁ X ₁₆ , P ₂ X ₁₇ , P ₃ X ₁₈ , and P ₄ X ₁₉ , and output p _placenta = P ₁ X ₁₆ +P ₂ X ₁₇ +P ₃ X ₁₈ +P ₄ X ₁₉ ,

Maternal postpartum hemorrhage risk value p _PPH generation module 134 is provided with: three input terminals, respectively input epidemiological risk value p _epidemiology , biochemical factor risk value p _biochemistry and placental factor risk value p _placenta , and one output terminal, output pregnancy Maternal postpartum hemorrhage risk value p _PPH :

E, B, and P are risk values represented by logistic regression coefficients, which are statistical values of experimental data, among which:

70>P ₁ >P ₄ >P ₃ >P ₂ >10, 16>E ₇ >E ₁₃ >B ₂ >E ₁₀ >10, 10>E ₃ >E ₁₂ >E ₉ >E ₆ >E ₁ >E ₁₁ >4, 2.6>E ₄ >E ₅ >E ₂ >B ₁ >E ₈ >1.8, "^" is the exponentiation symbol,

The onset risk alarm module 14 of maternal postpartum hemorrhage includes: the numerical alarm module 141 of the onset risk of maternal postpartum hemorrhage and the sound alarm module 142 of the onset risk of maternal postpartum hemorrhage;

Maternal postpartum hemorrhage incidence risk value alarm module 141, the input terminal is connected to the output end of the maternal postpartum hemorrhage risk value p _PPH generation module 134, when the maternal postpartum hemorrhage risk value p _PPH > _A5 , it will be displayed The pregnant woman is in a high-risk state, otherwise, it is in a non-high-risk state, A ₅ =12,

The dangerous sound alarm module 142 of postpartum hemorrhage in pregnant women, the input end is connected with the photoelectric signal output end of the light receiving tube in the center of the circle on the LED light emitting diode panel 2, when the total light intensity of the LED light emitting diode is greater than or equal to A _{At 6} o'clock, the buzzer 3 is triggered to alarm, A ₆ =23.2cd;

LED light-emitting diode panel 2, with one of the light-receiving tubes as the center of the circle, the circumference is incremented by 18° per frame, and the directions are distributed in different radius values from 0° to 360°, and 19 maternal postpartum hemorrhage risks are input respectively. Value E _j X _i , i=1,2...13, j=1,2...13, B ₁ X ₁₄ , B ₂ X ₁₅ , P ₁ X ₁₆ , P ₂ X ₁₇ , P ₃ X ₁₈ , P ₄ X ₁₉ of 19 LED light-emitting diodes, each of the LED light-emitting diodes is calculated from the distance R along the radial direction of the light receiving tube on the center of the circle: R=10×(1-E _factors /70) cm, E _factors Represents 19 maternal postpartum hemorrhage risk values E _j X _i , i=j=1, 2...13, B ₁ X ₁₄ , B ₂ X ₁₅ , P ₁ X ₁₆ , P ₂ X ₁₇ , P ₃ X _18. One of P ₄ X ₁₉ corresponding to the LED light-emitting diode,

When the light-receiving tube on the center of the circle receives the luminous flux I emitted by one or more of the 19 LED light-emitting diodes, I is expressed as I=constant2/R ² , and constant2 is the light flux emitted by each of the LED light-emitting diodes. The standard luminous flux of the luminescence.

The postpartum hemorrhage early warning system based on epidemiological, biochemical and placental factors provided by the present invention includes multiple high-risk factors of the risk of postpartum hemorrhage in pregnant women, and the multiple high-risk factors can be introduced into the LED light-emitting diode panel at the same time. The LED lights corresponding to the high-risk factors, and according to the different contribution values of different high-risk factors to the risk of postpartum hemorrhage in pregnant women, are converted into the risk values of the high-risk factors, and the numerical alarm is given to the risk of postpartum hemorrhage in pregnant women, and through LED light-emitting diodes The total luminous flux of the panel triggers a buzzer alarm to sound an alarm for the risk of maternal postpartum hemorrhage.

The present invention can comprehensively and objectively evaluate the high-risk factors of postpartum hemorrhage, can predict the risk of disease from the whole, and can specifically find the pathogenic factors for symptomatic treatment, and can predict the occurrence of postpartum hemorrhage at an early stage, and carry out effective treatment as soon as possible. Targeted intervention is a monitoring method for pregnant women throughout their pregnancy. It makes up for the previous scoring method that can only be used in the third trimester of pregnancy, or even in the estimation of labor, which is helpful to formulate prevention and intervention measures for postpartum hemorrhage, standardize obstetricians' understanding of postpartum hemorrhage, and reduce pregnancy loss caused by postpartum hemorrhage. Maternal deaths are positive.

Description of drawings

Fig. 1 is the internal structure diagram of postpartum hemorrhage early warning system based on epidemiology, biochemistry and placenta factors, 1-computer, wherein, 11-the information import module of epidemiology, biochemistry and placenta factors of pregnant women, wherein, 111-pregnancy Maternal epidemiology and biochemical factors information import module, 112-maternal placenta factors information import module, 12-maternal postpartum hemorrhage incidence risk factor array switch module, among them, 121-maternal postpartum hemorrhage prevalence risk Pathology and biochemical factors array switch module, 122-maternal postpartum hemorrhage incidence risk of placental factors array switch module, 13-maternal postpartum hemorrhage incidence risk logistic regression value calculation module, 14-maternal postpartum hemorrhage incidence Danger alarm module, wherein, 141-maternal postpartum hemorrhage incidence risk numerical alarm module, 142-maternity postpartum hemorrhage incidence risk sound alarm module, 2-LED light-emitting diode panel, 3-buzzer alarm.

Fig. 2 is the information import module structural diagram of the epidemiology, biochemical and placental factors of pregnant women, 111-the information import module of epidemiology and biochemical factors of pregnant women, 112-the information import module of placental factors of pregnant women, Indicates the import of information.

Figure 3 is a structural diagram of the array switch module of the risk factors of postpartum hemorrhage in pregnant women, the array switch module of 121-the epidemiological and biochemical factors of the risk of postpartum hemorrhage in pregnant women, and 122-the placental factors of the risk of postpartum hemorrhage in pregnant women Array switch module.

Figure 4 is a structural diagram of the logistic regression value calculation module for the risk of postpartum hemorrhage in pregnant women.

FIG. 5 is a structural diagram of an LED light-emitting diode panel.

detailed description

The present invention mainly provides an early warning system for postpartum hemorrhage based on epidemiological, biochemical and placental factors, which is characterized in that it is a computer, LED light-emitting diode panel and buzzer alarm system for real-time monitoring and early warning of pregnant and lying-in women. The risk value calculation and early warning system for the risk of postpartum hemorrhage is shown in Figure 1, where:

The computer 1 is equipped with: an information import module 11 of epidemiology, biochemical and placental factors of pregnant women, an array switch module 12 of risk factors for postpartum hemorrhage in pregnant women, a logic regression value calculation module for the risk of postpartum hemorrhage in pregnant women 13 and the onset risk alarm module 14 of maternal postpartum hemorrhage, in which:

The information import module 11 of maternal epidemiology, biochemical and placental factors, as shown in Figure 2, comprises: the information import module 111 of maternal epidemiology and biochemical factors information import module 111 and maternal placental factors, wherein :

Maternal epidemiology and biochemical factor information import module 111 is provided with: a total of 13 epidemiological information input items marked with x' ₁ ~ x' ₁₃ , and the order of the 13 epidemiological information is: age , pregnancy body mass index, multiple pregnancy, family history of hypertension, history of adverse pregnancy, history of abdominal surgery, hypertensive disorder of pregnancy, first trimester bleeding, macrosomia, polyhydramnios, uterine ovarian fibroids, threatened premature labor and pelvic soft birth canal exception, where:

Age, when greater than or equal to the critical value A ₁ , input information x' ₁ =1, when the age is less than the critical value A ₁ , x' ₁ =0, A ₁ =35 years old,

When the body mass index during pregnancy is greater than or equal to the critical value A ₂ , input information x' ₂ =1; when the age is less than the critical value A ₂ , x' ₂ =0, A ₂ =25,

The remaining 11 pieces of information are represented by x' ₃ ~ x' ₁₃ in sequence, among them, when any piece of information exists, the corresponding epidemiological input signal value is 1, and when it does not exist, the corresponding epidemiological input signal value is 0; There are also two biochemical information input items marked with x' ₁₄ ~ x' ₁₅ , including: hemoglobin information x' ₁₄ and platelet count information x' ₁₅ , wherein:

When the hemoglobin information x' ₁₄ is less than or equal to the critical value A ₃ , the epidemiological input signal value is 1, and when it is greater than the critical value A ₃ , the epidemiological input signal value is 0, A ₃ =100c1, c1 is the concentration unit, expressed in grams per liter,

When the platelet count information x' ₁₅ is less than the critical value A ₄ , the input signal value is 1, and when it is greater than or equal to the critical value A ₄ , the input signal value is 0, A ₄ =100×10 ⁹ /L;

The information import module 112 of maternal placental factors is provided with: input items of 4 placental factor information marked with x' ₁₆ ~ x' ₁₉ , and the 4 placental factor information is expressed in sequence as: placenta previa information x' _16. Placental abruption information x' ₁₇ , placental retention information x' ₁₈ and placental adhesion information x' ₁₉ , wherein: when any one of the placental factor information exists, its input signal value is 1, and if it does not exist, the input signal value is 0,

The information import module 11 of the epidemiology, biochemical and placental factors of the pregnant and lying-in women, when any input signal in the input signal value _{x'i exists, the corresponding output signal x"i value} is 1, if not exist , the corresponding output signal x” _i value is 0, i=1,2,3…i,…,19,

The array switch module 12 of risk factors for postpartum hemorrhage in pregnant women, as shown in FIG. The array switch module 122, wherein:

The epidemiological and biochemical factor array switch module 121 of the risk of maternal postpartum hemorrhage is provided with: 13 epidemiological information input terminals respectively connected with 13 of the maternal epidemiological and biochemical factor information import module 111 Two maternal epidemiological information output terminals are connected, input epidemiological information x" _i , i=1, 2...13; two biochemical information input terminals are respectively connected with the maternal epidemiological and biochemical factor information The two biochemical information output terminals of the import module 111 are connected, input biochemical factor information x" _i , i=14,15,

The placental factor array switch module 122 of the risk of maternal postpartum hemorrhage is provided with: four input terminals of the placental factor information, respectively connected to the corresponding output terminals of the information import module 112 of the maternal placental factor, input Placental factor information x" _i , i=16,17,18,19,

The array switch module 121 of the epidemiological and biochemical factors of the risk of postpartum hemorrhage in pregnant women is provided with an output terminal corresponding to the input 15 pieces of information, and outputs 15 risk factor values of epidemiological and biochemical factors x ₁ ~ x ₁₅ , when there is an input signal value x” _i , x” _i = 1, then the output corresponding risk factor value x ₁ ～ x ₁₅ takes a value of 1, when there is no input signal x” _i = 0, then the output The risk factor value x _i takes the value of 0, i=1,2...15,

The placental factor array switch module 122 of the risk of postpartum hemorrhage in pregnant women is provided with an output terminal corresponding to the input information of 4 placental factors, and outputs 4 placental risk factor values x ₁₆ ~ x ₁₉ , when there is an input signal x When " _i ", x" _i = 1, then the output corresponding risk factor value x _i is 1, if there is no input signal, x" _i = 0, then the output corresponding risk factor value x _i =0, i =16,17,18,19,

The 19 output signals x _i , i=1, 2...19, are called risk factor values,

The logistic regression value calculation module 13 of the risk of postpartum hemorrhage in pregnant women, as shown in Figure 4, is provided with: an epidemiological risk value p _epidemiology generation module 131, a biochemical factor risk value p _biochemistry generation module 132, and a placental factor risk value p _placenta generation module 133 and maternal postpartum hemorrhage risk value p _PPH generation module 134, wherein,

The epidemiology risk value p _epidemiology generating module 131 is provided with 13 epidemiological risk factor value input terminals, and the epidemiology in the module 121 is switched with the array of epidemiological and biochemical factors of the incidence risk of maternal postpartum hemorrhage The 13 output terminals of the risk factor value are connected, input x ₁ ~ x ₁₃ , a total of 13 epidemiological risk factor values _xi , when _xi exists, _xi = 1, the output is the epidemiological risk value X _i , X _i = 1, if _xi does not exist, _xi = 0, epidemiological risk value Xi = 0, _i = 1, 2, 3...i,..., 13, also set: epidemiological risk coefficient E _j , j=1,2,3...j,...,13, corresponding to the X _i along the serial number, multiplied to obtain 13 _{epidemiological} risk values E _j X _i , the output is epidemic = ∑ _{i, j} E _j X _i , i=j=1,2...13,

The biochemical risk value p _biochemistry generation module 132 is provided with: 2 biochemical risk factor value input terminals, and the array switch module 121 of the biochemical risk factor value of the epidemiological and biochemical factors of the maternal postpartum hemorrhage risk The corresponding two output terminals in x _i are connected, input x ₁₄ ~ x ₁₅ , a total of two biochemical risk factors x _i values, when x _i exists, x _i =1, the output is biochemical risk value X _i , Xi ₌ 1. If x _i does not exist, x _i = 0, biochemical risk value Xi ₌ 0, i = 14, 15, and also set: biochemical risk coefficients B ₁ and B ₂ , following the serial numbers and the said X ₁₄ , X ₁₅ corresponds to each other, multiplying them to get 2 biochemical hazard values B ₁ X ₁₄ and B ₂ X ₁₅ , output p _biochemistry = B ₁ X ₁₄ +B ₂ X ₁₅ ,

The placenta factor risk value p _placenta generating module 133 is provided with: 4 placenta risk factor value input terminals, and 4 output terminals of the placenta risk factor value in the placenta factor array switching module 122 of the maternal postpartum hemorrhage risk Connected, input x ₁₆ ~ x ₁₉ a total of 4 placental risk factors x _i values, when x _i exists, x _i = 1, the output is placental risk value X _i , Xi = 1, if x _i does not exist, x _{i i} = 0, placental risk value X _i = 0, i = 16, 17, 18, 19, also set: placental risk coefficients P ₁ , P ₂ , P ₃ , P ₄ , following the serial numbers and the X ₁₆ , X ₁₇ , X ₁₈ , and X ₁₉ correspond to each other, and multiply them to obtain four placental risk values P ₁ X ₁₆ , P ₂ X ₁₇ , P ₃ X ₁₈ , and P ₄ X ₁₉ , and output p _placenta = P ₁ X ₁₆ +P ₂ X ₁₇ +P ₃ X ₁₈ +P ₄ X ₁₉ ,

Maternal postpartum hemorrhage risk value p _PPH generation module 134 is provided with: three input terminals, respectively input epidemiological risk value p _epidemiology , biochemical factor risk value p _biochemistry and placental factor risk value p _placenta , and one output terminal, output pregnancy Maternal postpartum hemorrhage risk value p _PPH :

E, B, and P are risk values represented by logistic regression coefficients, which are statistical values of experimental data, among which:

70>P ₁ >P ₄ >P ₃ >P ₂ >10, 16>E ₇ >E ₁₃ >B ₂ >E ₁₀ >10, 10>E ₃ >E ₁₂ >E ₉ >E ₆ >E ₁ >E ₁₁ >4, 2.6>E ₄ >E ₅ >E ₂ >B ₁ >E ₈ >1.8, "^" is the exponentiation symbol, where:

P ₁ is the risk factor of placenta previa, P ₄ is the risk factor of placenta adhesion, P ₃ is the risk factor of retained placenta, P ₂ is the risk factor of placental abruption;

E ₇ is the risk factor of hypertensive disorders during pregnancy, E ₁₃ is the risk factor of abnormal pelvic soft birth canal, B ₂ is the risk factor of platelet count less than 100×10 ⁹ /L, E ₁₀ is the risk factor of polyhydramnios;

E ₃ is the risk factor of multiple pregnancy, E ₁₂ is the risk factor of threatened preterm birth, E ₉ is the risk factor of macrosomia, E ₆ is the risk factor of abdominal surgery history, E ₁ is the risk factor of age greater than or equal to 35 years old, E ₁₁ is the risk factor of uterus and ovary fibroid risk factor;

E ₄ is the risk factor of family history of hypertension, E ₅ is the risk factor of adverse pregnancy and childbirth history, E ₂ is the risk factor of BMI greater than or equal to 25 during pregnancy, B ₁ is the risk factor of hemoglobin less than or equal to 100cl, E ₈ is bleeding in the first trimester risk factor,

The onset risk alarm module 14 of maternal postpartum hemorrhage includes: the numerical alarm module 141 of the onset risk of maternal postpartum hemorrhage and the sound alarm module 142 of the onset risk of maternal postpartum hemorrhage;

Maternal postpartum hemorrhage incidence risk value alarm module 141, the input terminal is connected to the output end of the maternal postpartum hemorrhage risk value p _PPH generation module 134, when the maternal postpartum hemorrhage risk value p _PPH > _A5 , it will be displayed The pregnant woman is in a high-risk state, otherwise, it is in a non-high-risk state, A ₅ =12,

The dangerous sound alarm module 142 of postpartum hemorrhage in pregnant women, the input end is connected with the photoelectric signal output end of the light receiving tube in the center of the circle on the LED light emitting diode panel 2, when the total light intensity of the LED light emitting diode is greater than or equal to A _{At 6} o'clock, the buzzer 3 is triggered to alarm, A ₆ =23.2cd;

LED light-emitting diode panel 2, as shown in Figure 5, takes one of the light-receiving tubes as the center of the circle, increments by 18° per frame on the circumference, and distributes in order of different radius values from 0° to 360°, and input 19 respectively. Maternal postpartum hemorrhage risk value E _j X _i , i=j=1,2…13, B ₁ X ₁₄ , B ₂ X ₁₅ , P ₁ X ₁₆ , P ₂ X ₁₇ , P ₃ X ₁₈ , P ₄ X ₁₉ of 19 LED light-emitting diodes, each of the LED light-emitting diodes is calculated from the distance R along the radial direction of the light receiving tube on the center of the circle: R=10×(1-E _factors /70) cm, E _factors Represents 19 maternal postpartum hemorrhage risk values E _j X _i , i=1,2...13, j=1,2...13, B ₁ X ₁₄ , B ₂ X ₁₅ , P ₁ X ₁₆ , P ₂ One of X ₁₇ , P ₃ X ₁₈ , and P ₄ X ₁₉ corresponding to the LED light-emitting diode,

When the light-receiving tube on the center of the circle receives the luminous flux I emitted by one or more of the 19 LED light-emitting diodes, I is expressed as I=constant2/R ² , and constant2 is each of the LED light-emitting diodes The standard luminous flux emitted.

Claims (1)

1. The early warning system for postpartum hemorrhage based on epidemiology, biochemical and placental factors is characterized in that it is a system for real-time monitoring and early warning of the risk of postpartum hemorrhage in pregnant and lying-in women that is composed of a computer, LED light-emitting diode panel and buzzer alarm. Dangerous value calculation and early warning system, among which: The computer (1) is equipped with: an information import module (11) of epidemiology, biochemical and placental factors of pregnant women, an array switch module (12) of risk factors for postpartum hemorrhage in pregnant women, and a risk factor for postpartum hemorrhage in pregnant women The logistic regression value calculation module (13) and the incidence risk alarm module (14) of maternal postpartum hemorrhage, wherein: The information import module (11) of maternal epidemiology, biochemical and placental factors, including: the information import module (111) of maternal epidemiology and biochemical factors and the information import module (112) of maternal placental factors, wherein : The maternal epidemiology and biochemical factor information import module (111), is provided with: a total of 13 epidemiological information input items marked with x' ₁ ~ x' ₁₃ , and the order of the 13 epidemiological information is as follows: : Age, gestational body mass index, multiple pregnancy, family history of hypertension, history of adverse pregnancy, history of abdominal surgery, hypertensive disorders of pregnancy, first trimester bleeding, macrosomia, polyhydramnios, uterine and ovarian fibroids, threatened preterm labor and pelvic Abnormalities of the soft birth canal, in which: Age, when greater than or equal to the critical value A ₁ , input information x' ₁ =1, when the age is less than the critical value A ₁ , x' ₁ =0, A ₁ =35 years old, When the body mass index during pregnancy is greater than or equal to the critical value A ₂ , input information x' ₂ =1; when the age is less than the critical value A ₂ , x' ₂ =0, A ₂ =25, The remaining 11 pieces of information are represented by x' ₃ ~ x' ₁₃ in sequence, among them, when any piece of information exists, the corresponding epidemiological input signal value is 1, and when it does not exist, the corresponding epidemiological input signal value is 0; There are also two biochemical information input items marked with x' ₁₄ ~ x' ₁₅ , including: hemoglobin information x' ₁₄ and platelet count information x' ₁₅ , wherein: When the hemoglobin information x' ₁₄ is less than or equal to the critical value A ₃ , the corresponding epidemiological input signal value is 1, and when it is greater than the critical value A ₃ , the epidemiological input signal value is 0, A ₃ =100c1, c1 is the concentration unit, expressed in grams per liter, When the platelet count information x' ₁₅ is less than the critical value A ₄ , the corresponding epidemiological input signal value is 1, and when it is greater than or equal to the critical value A ₄ , the epidemiological input signal value is 0, A ₄ = 100×10 ⁹ pieces/L; The information import module (112) of maternal placental factors is provided with: input items of 4 placental factor information marked with x' ₁₆ ~ x' ₁₉ , and the information of the 4 placental factors is expressed in sequence as: placenta previa information x' ₁₆ , placental abruption information x' ₁₇ , placental retention information x' ₁₈ and placental adhesion information x' ₁₉ , wherein: when any of the placental factor information exists, its input signal value is 1, and if it does not exist, input Signal value is 0, The information import module (11) of the epidemiology, biochemical and placental factors of the pregnant and lying-in women, when any input signal in the input signal value _{x'i exists, the corresponding output signal x"i value} is 1, if When it does not exist, the corresponding output signal x” _i value is 0, i=1,2,3…i,…,19, The array switch module (12) of risk factors for the incidence of maternal postpartum hemorrhage, including: the array switch module of epidemiological and biochemical factors for the incidence risk of maternal postpartum hemorrhage (121) and the array of placental factors for the incidence risk of maternal postpartum hemorrhage A switch module (122), wherein: The epidemiological and biochemical factor array switch module (121) of the risk of maternal postpartum hemorrhage is provided with: 13 epidemiological information input terminals are respectively connected with the maternal epidemiological and biochemical factor information import module ( 111) are connected to 13 maternal epidemiological information output terminals, and input epidemiological information x" _i , i=1, 2...13; two biochemical information input terminals are respectively connected to the maternal epidemiological information Be connected with two biochemical information output ends of biochemical factor information import module (111), input biochemical factor information x " _i , i=14,15, The placenta factor array switch module (122) of the risk of maternal postpartum hemorrhage is provided with: four placenta factor information input terminals, corresponding to the corresponding output of the maternal placenta factor information import module (112) connected to each other, input placental factor information x" _i , i=16,17,18,19, The array switch module (121) of the epidemiological and biochemical factors of the risk of postpartum hemorrhage in pregnant women is provided with an output terminal corresponding to the input 15 pieces of information, and outputs the risk factor value x of 15 epidemiological and biochemical factors ₁ ～x ₁₅ , when there is an input signal value x” _i , x” _i = 1, then the output corresponding risk factor value x ₁ ～ x ₁₅ takes a value of 1, and when there is no input signal x” _i = 0, then The output risk factor value x _i takes the value of 0, i=1,2...15, The placental factor array switch module (122) of the risk of postpartum hemorrhage in pregnant women is provided with an output terminal corresponding to the input 4 placental factor information, and outputs 4 placental risk factor values x ₁₆ ~ x ₁₉ , when there is an input When the signal is x" _i , x" _i = 1, then the output corresponding risk factor value x _i is 1, if there is no input signal, x" _i =0, then the output corresponding risk factor value x _i =0 , i=16,17,18,19, The 19 output signals x _i , i=1, 2...19, are called risk factor values, The logistic regression value calculation module (13) for the risk of postpartum hemorrhage in pregnant women includes: an epidemiological risk value p _epidemiology generation module (131), a biochemical factor risk value p _biochemistry generation module (132), and a placental factor risk value p _placenta generation module (133) and maternal postpartum hemorrhage risk value p _PPH generation module (134), wherein, The epidemiology risk value p _epidemiology generating module (131) is provided with 13 epidemiological risk factor value input terminals, and the array switch module (121) of the epidemiological and biochemical factors of the maternal postpartum hemorrhage risk The 13 output terminals of the epidemiological risk factor value are connected, input x ₁ ~ x ₁₃ a total of 13 epidemiological risk factor values _xi , when _xi exists, _xi = 1, the output is the epidemiological risk value Xi, Xi _{= 1, if x i does} not exist, x _{i =} 0, epidemiological risk value Xi ₌ 0, i = 1,2,3...i,...,13, there is also: epidemiological Epidemiology risk coefficient E _j , j=1,2,3...j,...,13, corresponding to the X _i along the serial number, multiplied to obtain 13 _{epidemiological} risk values E _j X _i , the output is epidemic = ∑ _{i, j} E _j X _i , i=j=1,2...13, The biochemical factor risk value p _biochemistry generation module (132) is provided with: 2 biochemical risk factor value input terminals, and the array switch module (121) of the epidemiology and biochemical factors of the maternal postpartum hemorrhage risk The corresponding two output terminals in x _i of the risk factor value are connected, input x ₁₄ ~ x ₁₅ , a total of 2 biochemical risk factor x _i values, when x _i exists, x _i = 1, and the output is biochemical risk value X _i , Xi = 1, if x _i does not exist, x _{i =} 0, biochemical risk value Xi ₌ 0, i = 14, 15, also set: biochemical risk coefficients B ₁ and B ₂ , follow the serial number and all Said X ₁₄ and X ₁₅ correspond to each other, multiplying them to obtain two biochemical hazard values B ₁ X ₁₄ and B ₂ X ₁₅ , output p _biochemistry = B ₁ X ₁₄ +B ₂ X ₁₅ , The placenta factor risk value p _placenta generating module (133) is provided with: 4 placenta risk factor value input ends, and the placenta risk factor value in the array switch module (122) of the placenta factor of the maternal postpartum hemorrhage risk The 4 output terminals are connected, input x ₁₆ ~ x ₁₉ , a total of 4 placental risk factors _xi values, when _xi exists, _xi = 1, the output is the placental risk value X _i , Xi ₌ 1, if _xi is not When it exists, x _i = 0, placental risk value Xi ₌ 0, i = 16, 17, 18, 19, there are also: placental risk coefficients P ₁ , P ₂ , P ₃ , P ₄ X ₁₆ , X ₁₇ , X ₁₈ , and X ₁₉ respectively correspond to each other, and multiply to obtain four placental risk values P ₁ X ₁₆ , P ₂ X ₁₇ , P ₃ X ₁₈ , and P ₄ X ₁₉ , and output p _placenta = P ₁ X ₁₆ +P ₂ X ₁₇ +P ₃ X ₁₈ +P ₄ X ₁₉ , Maternal postpartum hemorrhage risk value p _PPH generation module (134), equipped with: three input terminals, respectively input epidemiological risk value p _epidemiology , biochemical factor risk value p _biochemistry and placental factor risk value p _placenta , an output terminal, Output the risk value p _PPH of postpartum hemorrhage in pregnant women: E, B, and P are risk values represented by logistic regression coefficients, which are statistical values of experimental data, among which: 70>P ₁ >P ₄ >P ₃ >P ₂ >10, 16>E ₇ >E ₁₃ >B ₂ >E ₁₀ >10, 10>E ₃ >E ₁₂ >E ₉ >E ₆ >E ₁ >E ₁₁ >4, 2.6>E ₄ >E ₅ >E ₂ >B ₁ >E ₈ >1.8, "^" is the exponentiation symbol, The onset risk alarm module (14) of maternal postpartum hemorrhage includes: the numerical alarm module (141) of the onset risk of maternal postpartum hemorrhage and the sound alarm module (142) of the onset risk of maternal postpartum hemorrhage; In the maternal postpartum hemorrhage risk value alarm module (141), the input terminal is connected to the output terminal of the maternal postpartum hemorrhage risk value p _PPH generation module (134), when the maternal postpartum hemorrhage risk value p _PPH > A ₅ indicates that the pregnant woman is in a high-risk state, otherwise, it is in a non-high-risk state, A ₅ =12, The risk sound alarm module (142) for postpartum hemorrhage in pregnant women, the input end is connected with the photoelectric signal output end of the light receiving tube in the upper circle center of the LED light emitting diode panel (2), when the total light of the LED light emitting diode is strong When it is equal to or equal to A6, the buzzer ( ₃ ) is triggered to alarm, A6= _23.2cd ; LED light-emitting diode panel (2), with one of the light-receiving tubes as the center of the circle, the circumference is incremented by 18° per frame, and the directions are distributed in different radius values from 0° to 360°, and 19 maternal postpartum hemorrhage are respectively input Risk value E _j X _i , i=j=1,2...13, 19 of B ₁ X ₁₄ , B ₂ X ₁₅ , P ₁ X ₁₆ , P ₂ X ₁₇ , P ₃ X ₁₈ , P ₄ X ₁₉ LED light-emitting diodes, the distance R of each of the LED light-emitting diodes along the radial direction from the light receiving tube on the center of the circle is calculated as follows: R=10×(1-E _factors /70) cm, and E _factors represent 19 of them. Describe the risk value of postpartum hemorrhage E _j X _i , i=j=1,2...13, B ₁ X ₁₄ , B ₂ X ₁₅ , P ₁ X ₁₆ , P ₂ X ₁₇ , P ₃ X ₁₈ , P ₄ One of X ₁₉ corresponding to the LED light-emitting diode, When the light-receiving tube on the center of the circle receives the luminous flux I emitted by one or more of the 19 LED light-emitting diodes, I is expressed as I=constant2/R ² , and constant2 is each of the LED light-emitting diodes The standard luminous flux emitted.