CN103550380A - Traditional Chinese medicine composition for treating hyperostosis - Google Patents
Traditional Chinese medicine composition for treating hyperostosis Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for treating hyperostosis. The composition consists of musk, gecko, lycopodium clavatum, caulis spatholobi, beautiful sweetgum fruit, ground beeltle, white paeony root, frankincense, prepared rhizome of rehmannia, the root of bidentate achyranthes, astragalus membranaceus, herba epimedii, angelica sinensis, bark of himalayan coralbean, paniculate swallowwort root, zaocys dhumnade, caulis sinomenii, radix aconiti preparata, prepared kusnezoff monkshood root, aconitine, cortex periplocae, chinese starjasmine stem and mistletoe. By adding general excipients according to a conventional process, the traditional Chinese medicine composition disclosed by the invention is prepared into clinically acceptable tablets, capsules, granules, pills, oral liquid, emplastrum, spray, ointments, liniments or tinctures. The traditional Chinese medicine composition disclosed by the invention has the effects of promoting blood circulation to remove blood stasis, relaxing tendons, activating collaterals, diminishing inflammation, relieving pain and the like, has remarkable effects for treating cervical bone hyperplasia, lumbar bone hyperplasia, knee bone hyperplasia and the like, and causes no toxic and side effects as well.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, particularly relate to a kind of Chinese medicine composition for the treatment of hyperosteogeny.
Background technology
Bone matrix hyperplasia claims again hyperplastic osteoarthritis, osteoarthritis (OA), degenerated arthrosis, senile arthritis, hypertrophiarthritis, because the soft tissue degeneration such as the cartilage that forms joint, intervertebral disc, ligament, degeneration, edge, joint form bony spur, the variations such as synovial membrane is plump, and there is osteoclasia, cause Secondary cases hyperosteogeny, cause joint deformity, when being subject to abnormal load, cause arthralgia, a kind of disease of the symptoms such as limitation of activity.Divide two kinds of constitutional and Secondary cases.Multiple middle age or the old people who is born in more than 45 years old of this disease, male is more than women, and heavy worker and the athlete of conventional waist activity easily suffer from this disease, are most commonly in the joints such as knee joint, hip, lumbar vertebra, cervical vertebra, elbow.
Summary of the invention
The object of the invention is to provide a kind of Chinese medicine composition for the treatment of hyperosteogeny.
The present invention is achieved through the following technical solutions:
The crude drug of Chinese medicine composition of the present invention consists of:
The raw material composition of Chinese medicine composition of the present invention is preferably:
The raw material composition of Chinese medicine composition of the present invention is preferably:
The raw material composition of Chinese medicine composition of the present invention is preferably:
Chinese medicine composition of the present invention adds conventional adjuvant to make the tablet of clinical acceptance, capsule, granule, pill, oral liquid, emplastrum, spray, ointment, liniment or tincture according to common process.
Chinese medicine composition of the present invention has blood circulation promoting and blood stasis dispelling, relaxing muscles and tendons and activating QI and blood in the collateral, and the effects such as anti-inflammatory analgetic, to treatment hyperosteogeny of cervical vertebra, lumbar vertebra hyperosteogeny, knee joint hyperosteogeny texts is remarkable, and has no side effect.
Experimental example is used for further illustrating the present invention below, but is not limited to the present invention.
One, experimental example
1, clinical observation
Capsule of the present invention (according to embodiment 1 method preparation) treatment hyperosteogeny 100 examples, male's 50 examples wherein, women's 50 examples.
2, medicament selection
Capsule of the present invention (according to embodiment 1 method preparation), 0.8g/ grain, every day three times, each 2.
3, diagnostic criteria
1. this patient mostly is 40 years old above middle-aged and elderly people, and with the stiff pain of waist or occur the symptoms such as numbness of lower limbs, the visible part patient lumbar physiological-curvature of having a medical check-up is abnormal; Lumbar vertebra both sides muscle has tenderness.
2. the change of lumbar X line sheet (normotopia, side position, left and right loxosis), as patient can have lumbar curvature abnormal, lumbar vertebra lateral bending, lumbar vertebra gap turn narrow, lumbar vertebra and facet joint hypertrophy, lumbar spondylolisthesis, the changes such as intervertebral foramina stenosis.
3. the various symptoms that lumbar hyperosteogency produces should differentiate with multiple lumbar disc disease, and as prolapse of lumbar intervertebral disc, vertebral body sends out the region between the heart and the diaphragm deformity, vertebral tumor, the diseases such as tuberculosis of spine.
4, criterion of therapeutical effect:
The Standardization of diagnosis and curative effect > > that cures the desease in the < < implementing for 1994 with reference to State Administration of Traditional Chinese Medicine drafts as follows:
Clinical recovery: tcm clinical practice symptom, sign disappear or substantially disappear;
Effective: tcm clinical practice symptom, sign obviously change;
Effective: tcm clinical practice symptom, sign all take a favorable turn;
Invalid: tcm clinical practice symptom, sign are all not improved;
5, therapeutic outcome
The Comparison of therapeutic of table 1 treatment hyperosteogeny
| Group | Treatment number | Recovery from illness | Effective | Effectively | Invalid | Total effective rate |
| Treatment group | 100 | 65 | 20 | 13 | 2 | 98％ |
6, conclusion
Treatment group of the present invention is taken respectively three courses for the treatment of (9 days each courses for the treatment of) of capsule of the present invention treatment hyperosteogeny (according to embodiment 1 method preparation), and total effective rate is 98%.
7, discuss
Moschus in pharmaceutical composition crude drug of the present invention: pungent, temperature, GUIXIN, spleen channel.The refreshment of having one's ideas straightened out, promoting blood circulation to restore menstrual flow, pain relieving.Gekko Swinhonis: salty, cold.Slightly poisonous.Dispel the wind, active, eliminating stagnation.Osteomyelitis, tuberculous lymphadenitis, tumor.Arresting convulsion, removing toxic substances.Control paralysis due to windstroke, severe and migratory arthralgia pain, wind-phlegm infantile convulsion, scrofula, malignant boil.Herba Lycopodii: meridian distribution of property and flavor toil temperature, enters Liver Channel.Expelling wind and cold. dehumidifying detumescence, relaxing muscles and tendons and activating QI and blood in the collateral.For anemofrigid-damp arthralgia, muscle arteries and veins contracture pain carbuncle.External is controlled osteopatia sprain and is swollen and ache.Caulis Spatholobi: bitter, sweet, temperature.Return liver, kidney channel.Function cures mainly: enrich blood, invigorate blood circulation, dredging collateral.For menoxenia, blood deficiency and yellow complexion, paralysis and numbness, rheumatic arthralgia.< < A Supplement to the Compendium of Materia Medica > >: invigorate blood circulation, warm waist knee joint, paralysis.This is the dry mature fruit of Hamamelidaceae Plants Chinese sweet gum for Fructus Liquidambaris.Hardship, flat.Return liver, kidney channel.Function: dispelling, collateral-activating, diuretic stimulates the menstrual flow.Cure mainly: arthralgia, numbness contracture.Eupolyphaga Seu Steleophaga is the female worm dry body of Corydiidae insecticide eupolyphoge sinensis (Eupolyphaga sinensis Walker) or Ji eupolyphoge sinensis (Steleophaga plancyi, i.e. Boleny).Salty, cold; Slightly poisonous.Return Liver Channel.Removing blood stasis with potent drugs blood, reuniting the fractured tendons and bones.For injured bone, blood stasis amenorrhea, lump in the abdomen mass in the abdomen.The Radix Paeoniae Alba: picric acid is cool.Enter liver, spleen channel.Nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing is received antiperspirant.Olibanum: arduous, temperature.Enter the heart, liver, spleen channel.Function cures mainly: regulating qi and activating blood, analgesic therapy, chases after poison.Control coagulation of QI-blood, trusted subordinate's pain, carbuncle pyogenic infections from tumour or sore, traumatic injury.< < pearl sac > >: fixed all warps are pain.Radix Rehmanniae Preparata: sweet in the mouth; Warm in nature.Liver Channel; Kidney channel.Enrich blood moist; Benefit essence is filled out marrow.Radix Achyranthis Bidentatae: nature and flavor are bitter; Acid; Property is put down.Medicine dispels the wind; Blood circulation and stasis-eliminating medicine.< < herbal classic > >: main cold-damp flaccidity syndrome and arthralgia syndrome, spasm of the limbs, gonalgia can not be bent, by vim and vigour.The Radix Astragali: nature and flavor: sweet, tepor.Gui Jing: return lung, spleen, kidney channel.There is the effect that benefiting QI for strengthening the superficies, arresting sweating are admittedly de-, hold in the palm skin ulcer granulation promoting, inducing diuresis to remove edema.Herba Epimedii: acrid, sweet, warm.Return liver, kidney channel.Kidney-replenishing, bone and muscle strengthening, wind-damp dispelling.For impotence and seminal emission, muscles and bones flaccidity is soft, rheumatic arthralgia, numbness contracture.Radix Angelicae Sinensis: sweet in the mouth; Pungent; Bitter; Warm in nature.Return liver; The heart; Spleen channel.Hematonic; Emmenagogue; Analgesic.Cortex erythrinae is the dried bark of leguminous plant erythrina indica.Toil, flat.Enter liver, spleen channel.Wind-damp dispelling, the meridian dredging, parasite killing.Dispelling the wind and dampness pathogens arthralgia pain, dysentery, toothache, scabies.< < gathers medicinal herbs in the south of the Five Ridges and records > >: granulation promoting, and pain relieving, loose blood, steamed cold noodles skin, applies traumatic injury.Radix Cynanchi Paniculati: nature and flavor: pungent, temperature.Gui Jing: return Liver Channel, stomach warp.Function: the removing dampness of dispeling the wind, antalgesic-antipruritic.Cure mainly: for rheumatic arthralgia, stomachache distension, toothache, lumbago, injury from falling down.Zaocys: sweet, flat.Return Liver Channel.Dispel the wind, dredging collateral, relieving convulsion.For rheumatoid arthritis stubborn, numbness contracture, apoplexy facial hemiparalysis, hemiplegia, tic spasm.Caulis Sinomenii: the property of medicine: flat.Flavour of a drug: bitter, pungent.Gui Jing: return liver, spleen channel.Function: wind-damp dispelling, the meridian dredging.Cure mainly: for rheumatic arthralgia, arthroncus, paralysis pruritus.Radix Aconiti Preparata: pungent, bitter, heat; Poisonous.GUIXIN, liver,kidney,spleen warp.Expelling wind and removing dampness, antalgic.For anemofrigid-damp arthralgia, mastalgia, chest pain with distension sensation, arthralgia, trusted subordinate's cold type of pain, colic of cold type is had a pain, narcotic analgesic.Radix Aconiti Kusnezoffii Preparata: nature and flavor: pungent, bitter, heat; Poisonous.Gui Jing: GUIXIN, liver,kidney,spleen warp.Effect: expelling wind and removing dampness, antalgic.Cure mainly: for anemofrigid-damp arthralgia, arthralgia.Radix aconiti kongboensis: warm in nature, bitter in the mouth fiber crops, very toxic.Anti-inflammatory analgetic, expelling wind and removing dampness.Cortex Periplocae is the dry root bark of Asclepiadaceae plant P. sepium Bunge Periploca sepium Bge..Cortex Periplocae: pungent, bitter, temperature; Poisonous.Wind-damp dispelling, bone and muscle strengthening.For anemofrigid-damp arthralgia, soreness of the waist and knees, shortness of breath and palpitation, edema of lower limbs.Caulis Trachelospermi: hardship, is slightly cold.GUIXIN, liver, kidney channel.There is expelling wind and removing dampness, removing obstruction in the collateral to relieve pain, clearing away heat and cooling blood, the effect of removing toxic substances and promoting subsidence of swelling.Herba Visci: bitter in the mouth, sweet, property is flat.Return liver, kidney channel.Relaxing muscles and tendons and activating QI and blood in the collateral, promoting blood circulation to remove blood stasis.For bones and muscles pain, limbs contracture, aching pain in waist and back.The all medicine merging of the present invention have the effects such as blood circulation promoting and blood stasis dispelling, relaxing muscles and tendons and activating QI and blood in the collateral, anti-inflammatory analgetic, to treatment hyperosteogeny of cervical vertebra, and lumbar vertebra hyperosteogeny, knee joint hyperosteogeny texts is remarkable, and has no side effect.
Experimental example two, model case
Case 1: Wu, female, 55 years old.Symptom: at the beginning of patient 2011, start to feel that left leg swells, the tired pain in left hip joint place, whole left lower extremity is numb, does not check, and with " prednisone ", do not carry out closed treating, symptom alleviates.There is again above symptom in February, 2013.CT examination: lumbar vertebra L2-5 is hypertrophy in various degree, L3/4, L4/5 intervertebral disk hernia, compressing dural sac.May 13 examined, and pain numbness outside shank causes the hip arthralgia, movable and overcast and rainy increasing the weight of when heavy.Deep,thready and forceless pulse, red tongue, aversion to cold and cold limbs.Diagnosis: lumbar vertebra hyperosteogeny; Treatment: blood circulation promoting and blood stasis dispelling, relaxing muscles and tendons and activating QI and blood in the collateral, anti-inflammatory analgetic; By taking capsule of the present invention (according to embodiment 1 method preparation), treat two courses for the treatment of every day three times, each 2.Arthralgia is clearly better, and knee joint function obviously improves, and patient can normally walk, and continual cure recovers normal a course for the treatment of on inspection substantially.
Case 2: grandson, female, 48 years old.Symptom: the strong pain of cervical region before 20 days, numbness of the fingers, heavy when light when dizzy, light Shi Ruyi ordinary person, very dizzy when heavy.Diagnosis: hyperosteogeny of cervical vertebra; Treatment: heat clearing away relaxing muscles and tendons, promoting blood circulation to remove obstruction in the collateral; The application of the invention emplastrum (according to embodiment 2 method preparations) is treated a course for the treatment of, and patient is dizzy obviously to be alleviated.Continue again to use a course for the treatment of, the strong pain of patient's cervical region disappears, and range of motion obviously improves.Continue to strengthen a course for the treatment of, patient recovers normal substantially on inspection.
Case 3: Lee, female, 48 years old, people from Shandong, first visit on May 14 in 2007.Main suit: the right gonalgia 5 years, increases the weight of 3 years.Medical history: started to occur the right gonalgia before 5 years, local fearness is cool, and the cloudy day increases the weight of whenever, and take the photograph sheet and show in March, 2006: knee joint hyperosteogeny, though sought medical advice everywhere in recent years, to force on, western medicines in treatment does not all alleviate, on May 14th, 2007, examine deep-thready pulse, light red tongue.Diagnosis: 1. 2. rheumatic arthritis of right knee joint hyperosteogeny.Treatment: after detailed inspection, give patient for patient's practical situation and take tablet of the present invention (according to embodiment 3 method preparations), every day three times, each 2.Take after two courses for the treatment of, pain disappears completely.Continue to strengthen again treatment one month, recover on inspection normal completely
Following embodiment all can realize the effect of above-mentioned experimental example.
The specific embodiment
Embodiment 1 capsule
According to common process, add conventional adjuvant to make capsule said medicine.Every day three times, each 2.
Embodiment 2 emplastrumes
According to common process, add conventional adjuvant to make emplastrum said medicine.Paste every day 1.
Embodiment 3 tablets
According to common process, add conventional adjuvant to make tablet said medicine.Every day three times, each 2.
Embodiment 4 ointments
According to common process, add conventional adjuvant to make ointment said medicine.
Embodiment 5 granules
Said medicine is added to the agent of conventional adjuvant granulation according to common process.
Embodiment 6 sprays
According to common process, add conventional adjuvant to make spray said medicine.
Claims (7)
1. a Chinese medicine composition for the treatment of hyperosteogeny, is characterized in that, the crude drug of said composition consists of:
2. Chinese medicine composition as claimed in claim 1, is characterized in that, the crude drug of said composition consists of:
3. Chinese medicine composition as claimed in claim 1, is characterized in that, the crude drug of said composition consists of:
4. Chinese medicine composition as claimed in claim 1, is characterized in that, the crude drug of said composition consists of:
5. the Chinese medicine composition as described in one of claim 1-4, is characterized in that said composition adds conventional adjuvant to make the tablet of clinical acceptance, capsule, granule, pill, oral liquid, emplastrum, spray, ointment, liniment or tincture according to common process.
6. the application of the Chinese medicine composition as described in one of claim 1-4 in the medicine of preparation treatment hyperosteogeny.
7. the application of Chinese medicine composition as claimed in claim 6 in the medicine of preparation treatment hyperosteogeny, is characterized in that described hyperosteogeny refers to hyperosteogeny of cervical vertebra, lumbar vertebra hyperosteogeny or knee joint hyperosteogeny.
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| CN104623476A (en) * | 2015-01-15 | 2015-05-20 | 李兆瑞 | Traditional Chinese medicine composition for treating osteoproliferation |
| CN106266271A (en) * | 2016-09-08 | 2017-01-04 | 佛山市顺德区宝铜金属科技有限公司 | A kind of Chinese medicine composition treating cervical spondylosis |
| CN106266029A (en) * | 2015-06-04 | 2017-01-04 | 贵州中草医医院 | A kind of Chinese medicine composition treating prolapse of lumbar intervertebral disc, hyperosteogeny |
| CN106729587A (en) * | 2017-03-02 | 2017-05-31 | 冷桂英 | Treatment osteoproliferation, lumbar vertebra protrusion, the externally applied drug of spinal canal stenosis and application method |
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