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CN103519882B - Multi-electrode renal artery ablation catheter - Google Patents

Multi-electrode renal artery ablation catheter Download PDF

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Publication number
CN103519882B
CN103519882B CN201210233475.6A CN201210233475A CN103519882B CN 103519882 B CN103519882 B CN 103519882B CN 201210233475 A CN201210233475 A CN 201210233475A CN 103519882 B CN103519882 B CN 103519882B
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China
Prior art keywords
ablation
electrode
skeleton
ablation catheter
catheter
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Expired - Fee Related
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CN201210233475.6A
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CN103519882A (en
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李莉
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Abstract

A kind of Multi-electrode renal artery ablation catheter, the arteria renalis sympathetic nerve for hypertension PCI melts, and includes the ablation catheter and function handle of adjustable bent catheter sheath, adjustable diameter, wherein adjustable bent catheter sheath head end is flexible, is easy to ablation catheter to enter the arteria renalis;The ablation catheter skeleton diameter of adjustable diameter is adjustable, and has multiple electrodes, and each electrode has temperature sensor.The Multi-electrode renal artery ablation catheter that the present invention is provided, multiple points can disposably be melted, and ablation points are discontinuous, temperature-controllable, while arteria renalis sympathetic nerve treatment hypertension is removed, it is to avoid the risk of excessive ablation and arteria renalis hemadostewnosis, while because once melting, the use of operating time and X-ray can be greatly reduced, the accuracy of ablation is improved.

Description

Multi-electrode renal artery ablation catheter
Technical field
The present invention relates to medical instruments field, and in particular to a kind of arteria renalis sympathetic nerve for hypertension PCI Ablation catheter.
Background technology
Intractable hypertension, refers to the drug therapy in maximum tolerated dose(3 kinds of depressor including diuretics, which are combined, to be controlled Treat)Still it is unable to reach target blood pressure value.These patients are the High risk groups of major cardiovascular events.
In April, 2009, Krum etc. reports percutaneous catheter sympathetic renal nerve radiofrequency ablation intractable hypertension New technology.This method cuts off sympathetic renal nerve by RF ablation, and does not influence other bellies, pelvis or lower limb nerve Dominate, reached the purpose that severe complication is avoided while decompression.In November, 2010, one is related to 24 medical centers Perspective, the randomized controlled trial carried out, " Symplicity HTN-2 researchs " is published in lancet. “Symplicity HTN-2 researchs " result shows that enter to pass through conduit TSD to refractory hypertension patient, can obtain notable and lasting decompression and treat Effect.106 refractory hypertension patients are included in this experiment altogether, and test group patient adheres to carrying out multiple medicine connection after RSD is carried out Antihypertensive therapy is closed, control group patient only carries out multiple medicine therapeutic alliance.Test group patient blood pressure at 6th month averagely declines 32/12mmHg, control group patients' blood is without change.And research does not find the related complication of operation or adverse events, suffers from Person's Renal Function After is in order.
As a new technology, the apparatus matched also compares shortage, and currently used for clinical product, there is also many Problem, more product clinically is the Symplicity ablation systems of Medtronic companies, because of only one of which electrode Ablation, causes to operate more complicated, the problems such as RF ablation time is long.
CN102274074A discloses a kind of Multi-electrode open-type radio frequency ablation catheter, and one end of conduit is Open architecture, Easily occur to cause what ablation failed the problem of can not be brought into close contact with blood vessel when the arteria renalis goes sympathetic nerve to melt May.CN201469401U discloses a kind of helical form arteria renalis sympathetic nerve frequency ablation electrode catheter, and electrode is spiral knot Structure, design is simple, it is difficult to operate, the risk for equally having the problem of can not being brought into close contact blood vessel and causing ablation to fail.
The content of the invention
It is an object of the invention to provide a kind of arteria renalis sympathetic nerve ablation catheter simple to operate, dependable performance.According to The anatomical structure of the arteria renalis, the present invention can provide the electrode seal laminating arteria renalis blood vessel of ablation catheter, and diameter is adjustable, Duo Ge electricity The conduit that pole is melted simultaneously, can be greatly decreased the consumption of X-ray, while reducing operation difficulty.
To achieve the above object, the invention provides a kind of Multi-electrode renal artery ablation catheter, including adjustable bent catheter sheath, can The ablation catheter and function handle of diameter adjusting, described adjustable bent catheter sheath one end are fixed on the bending control piece of function handle, The free bend of the other end is controlled by bending control piece;The ablation catheter of the adjustable diameter includes at least two straight-adjustables At least one electrode is fixed on the skeleton in footpath, every skeleton straight section, each electrode passes through wire and the ablation apparatus of function handle Interface is connected, and ablation catheter one end is fixed in described skeleton one end, and the other end is fixed on bone that can be movable relative to ablation catheter On frame connector, skeleton control pipe one end of the ablation catheter is connected through skeleton connector with head end part, and the other end is fixed On the skeleton control piece of function handle, the skeleton control piece can control the diameter adjustment of the skeleton;The adjustable diameter One end of ablation catheter be fixed on the ablation catheter extension and contraction control part of function handle, can by ablation catheter extension and contraction control part Realize that the skeleton of the ablation catheter passes in and out the adjustable bent catheter sheath.
The skeleton structure of the adjustable diameter is that centre is straight section, and two ends are contracted to the Rugby structure of a bit.
The skeleton of the adjustable diameter is 2~8, more preferably 3~4.
The skeleton straight section length of the adjustable diameter is 10~30mm, according to the length of the arteria renalis, more preferably 15~ 20mm。
1~3 electrode is fixed with the straight section of the skeleton of the adjustable diameter, there can be 1 electrode on each skeleton, And 1~2 electrode is not distributed on another plane alternate or adjacent skeleton, and another does not put down Face alternate, each electrode connects a wire, the ablation apparatus interface connection of the other end and function handle, by radio frequency Ablation energy is transferred to electrode.
The skeleton of the adjustable diameter discharges a diameter of 3~10mm of rear straight section, root from the adjustable bent catheter sheath According to the normal dia of the arteria renalis, more preferably 3~8mm.
The adjustable bending pipe sheath is double lumen structure, and tube chamber leads to ablation catheter, and a tube chamber leads to traction fiber, it is described can Traction fiber one end in bend pipe sheath is adjusted to be fixed on the end of adjustable bending pipe sheath, the traction fiber that the other end is fixed on function handle is fixed On part, the free bend of adjustable bending pipe sheath can be realized by controlling the movement of traction fiber fixture, preferred angle of bend 0~ 90 degree, so that ablation catheter easily can enter in the arteria renalis.
Ablation apparatus interface is provided with the function handle, each electrode is connected by wire and the ablation apparatus interface Connect, the ablation apparatus interface can realize the connection with RF ablation instrument by connecting line, by transmission of radio-frequency energy to each Electrode.Melted it is further preferred that different electrodes can be chosen according to the architectural feature of the arteria renalis.
Each electrode is connected with temperature sensor, is connected by wire with the ablation apparatus interface, and by even Wiring can realize the connection with RF ablation instrument, and the temperature signal of each electrode is included on RF ablation instrument.
The radio frequency ablation catheter that the present invention is provided, can disposably melt multiple points, and ablation points are discontinuous, temperature-controllable, While arteria renalis sympathetic nerve treatment hypertension is removed, it is to avoid the risk of excessive ablation and arteria renalis hemadostewnosis, together Shi Yin once melts, and can greatly reduce the use of operating time and X-ray, improves the accuracy of ablation.
Brief description of the drawings
Fig. 1 is the structural representation of Multi-electrode renal artery ablation catheter.
Fig. 2 is the structural representation that Multi-electrode renal artery ablation catheter skeleton takes in adjustable bending pipe sheath.
Fig. 3 is the Multi-electrode renal artery ablation catheter schematic diagram that skeleton does not discharge in vivo.
Fig. 4 be Multi-electrode renal artery ablation catheter in vivo skeleton release after schematic diagram.
The explanation of reference
1st, adjustable bent catheter sheath;2nd, adjustable diameter ablation catheter;3rd, the skeleton of adjustable diameter;4th, electrode;5th, skeleton is connected Part;6th, skeleton control pipe;7th, head end part;8th, function handle;9th, control piece is bent;10th, ablation catheter extension and contraction control part;11st, bone Frame control piece;12nd, traction fiber fixture;13rd, ablation apparatus interface;14th, sustainer;15th, the arteria renalis;16th, kidney;RS:The arteria renalis Sympathetic nerve(Renal Sympathetic).
Embodiment
With reference to the accompanying drawings and examples, the specific embodiment of the invention is described further, following examples are only used In more clear explanation technical scheme, and it can not be limited the scope of the invention with this.
Fig. 1 show guide-tube structure schematic diagram of the present invention for the ablation of arteria renalis sympathetic nerve.The ablation catheter bag The ablation catheter 2 and function handle 8 of adjustable bent catheter sheath 1, adjustable diameter are included, described one end of adjustable bent catheter sheath 1 is fixed on work( 9 on the bending control piece of energy handle 8, the free bend of the other end is controlled by bending control piece 9;The ablation of the adjustable diameter The including of conduit 2 fix at least one electrode 4, each electrode 4 on the skeleton 3 of at least two adjustable diameters, the every straight section of skeleton 3 It is connected by wire with the ablation apparatus interface 13 of function handle 8, the one end of ablation catheter 2 is fixed in described one end of skeleton 3, another End is fixed on skeleton connector 5 that can be movable relative to ablation catheter, and one end of skeleton control pipe 6 of the ablation catheter is passed through Skeleton connector 5 is connected with head end part 7, and the other end is fixed on the skeleton control piece 11 of function handle 8, the skeleton control piece 11 can control the diameter adjustment of the skeleton 3;One end of the ablation catheter 2 of the adjustable diameter is fixed on disappearing for function handle 8 Melt on conduit extension and contraction control part 10, the skeleton 3 that can realize the ablation catheter by ablation catheter extension and contraction control part 10 passes in and out institute State adjustable bent catheter sheath 1.
The structure of skeleton 3 of adjustable diameter is that centre is straight section, and two ends are contracted to outside the Rugby structure of a bit, skeleton 3 Layer is that have sizing Nitinol in flexible macromolecule tubing, each skeleton, and its a diameter of 0.2~0.5mm can make skeleton 3 discharge the shape that design is kept after adjustable bent catheter sheath 1.
The skeleton 3 of adjustable diameter is 2~8, and more preferably 3~4, its straight section length is 10~30mm, dynamic according to kidney 1~3 electrode 4 is fixed with the length of arteries and veins 15, more preferably 15~20mm, straight section, there can be 1 electricity on each skeleton 3 Pole 4, and 1~2 electrode 4 is not distributed on another plane alternate or adjacent skeleton 3, and no longer One plane alternate, each electrode 4 connects a wire, the ablation apparatus interface 13 of the other end and function handle 8 Connection, electrode 3 is transferred to by radiofrequency ablation energy.Each electrode 3 is connected with temperature sensor, is disappeared by wire with described Melt equipment interface 13 to connect, and the connection with RF ablation instrument can be realized by connecting line, by the temperature signal of each electrode It is shown on RF ablation instrument.
The skeleton 3 of adjustable diameter is discharged by ablation catheter extension and contraction control part 10 from adjustable bent catheter sheath 1, and through bone Frame control piece 11 carries out the diameter control of skeleton 3, can be adjusted between 3~10mm, more excellent according to the normal dia of the arteria renalis Elect as and be adjusted between 3~8mm.
Adjustable bending pipe sheath 1 is double lumen structure, and a tube chamber leads to ablation catheter 2, and a tube chamber leads to traction fiber, traction fiber one End is fixed on the end of adjustable bending pipe sheath 1, and the other end is fixed on the traction fiber fixture 12 of function handle 8, can pass through control The free bend of adjustable bending pipe sheath 1 is realized in the movement of traction fiber fixture 12, angle of bend preferably at 0~90 degree so that Ablation catheter 2 easily can enter in the arteria renalis.
Ablation apparatus interface 13 is provided with function handle 8, each electrode 4 is connected by wire with ablation apparatus interface 13 Connect, ablation apparatus interface 13 can realize the connection with RF ablation instrument by connecting line, by transmission of radio-frequency energy to each electricity Pole 4.In actual use, different electrodes 4 can be chosen according to the architectural feature of the arteria renalis 15 and be melted.
Fig. 2 show the structural representation that Multi-electrode renal artery ablation catheter skeleton of the present invention takes in adjustable bending pipe sheath, passes through The ablation catheter extension and contraction control part 10 of function handle 8 is promoted backward, the skeleton of ablation catheter 2 can be pulled in adjustable bent catheter sheath 1, Adjusting skeleton control piece 11 simultaneously makes head end part 7 pull in adjustable bent catheter sheath 1, makes its laminating close.
Fig. 3 show the Multi-electrode renal artery ablation catheter of the present invention schematic diagram that skeleton does not discharge in vivo, and the arteria renalis is more The income adjustable bending pipe of pole ablation catheter skeleton 3 sheath 1, by femoral artery puncture, under X-ray guiding, into sustainer 14, will disappear Melt conduit to place to the entrance of the arteria renalis 14, the bending control piece 9 of control function handle 8, make the bending conjunction of adjustable bent catheter sheath 1 Suitable angle, is directed at the entrance of the arteria renalis 15, by adjustable bent catheter sheath 1 by promoting the ablation catheter of function handle 8 to stretch forward Control piece 10, makes the skeleton 3 of ablation catheter 2 release adjustable bent catheter sheath 1, into the arteria renalis 15.
Fig. 4 show Multi-electrode renal artery ablation catheter of the present invention in vivo skeleton release after schematic diagram.When ablation catheter 2 Skeleton 3 enter after the arteria renalis 15, skeleton control piece 11 is promoted backward, head end part 7 is touched skeleton connector 5, pastes skeleton 3 The vascular wall of the tight arteria renalis 15, assesses whether position is suitable by X-ray, such as position is improper, can be flexible by ablation catheter Control piece 10 and skeleton control piece 11 are adjusted, and after position is preferable, ablation apparatus interface 13 is connected into radiofrequency melting instrument, ginseng is set Number, is melted.In ablation procedure, the ablation temperature of each electrode is shown on radiofrequency melting instrument in real time, temperature such as occurs It is too high, the ablation of this electrode can be stopped, it is to avoid excessively ablation.
Described above is only the preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art For member, in the case where not departing from the early stage of the technology of the present invention principle, some improvements and modifications can also be made, these improvements and modifications Also it should be regarded as protection scope of the present invention.

Claims (10)

1. a kind of Multi-electrode renal artery ablation catheter, includes the ablation catheter and function handle of adjustable bent catheter sheath, adjustable diameter, its It is characterised by:
Described adjustable bent catheter sheath one end is fixed on the bending control piece of function handle, and the other end is controlled by bending control piece Free bend;
The ablation catheter of the adjustable diameter is included fixed at least one on the skeleton of at least two adjustable diameters, every skeleton straight section Individual electrode, each electrode is connected by wire with the ablation apparatus interface of function handle, and described skeleton one end is fixed on ablation and led Pipe one end, the other end is fixed on skeleton connector that can be movable relative to ablation catheter, the skeleton control of the ablation catheter Pipe one end is connected through skeleton connector with head end part, and the other end is fixed on the skeleton control piece of function handle, the skeleton Control piece can control the diameter adjustment of the skeleton;
One end of the ablation catheter of the adjustable diameter is fixed on the ablation catheter extension and contraction control part of function handle, passes through ablation The skeleton that the ablation catheter can be achieved in conduit extension and contraction control part passes in and out the adjustable bent catheter sheath;
The Multi-electrode renal artery ablation catheter adapts to the anatomical structure of the arteria renalis, and diameter is adjustable, can make the electrode of ablation catheter Arteria renalis blood vessel is brought into close contact, can be while arteria renalis sympathetic nerve treatment hypertension be removed, it is to avoid excessively melt and kidney The narrow risk of arteries, and can realize that multiple electrodes melt simultaneously, ablation time can be shortened, ablation accuracy is improved.
2. the Multi-electrode renal artery ablation catheter as described in claim 1, it is characterised in that the skeleton structure of the adjustable diameter It is that centre is straight section, two ends are contracted to the Rugby structure of a bit.
3. the Multi-electrode renal artery ablation catheter as described in claim 2, it is characterised in that the skeleton of the adjustable diameter is 2 ~8.
4. the Multi-electrode renal artery ablation catheter as described in claim 3, it is characterised in that the skeleton straight section of the adjustable diameter Length is 10~30mm.
5. the Multi-electrode renal artery ablation catheter as described in claim 4, it is characterised in that the skeleton of the adjustable diameter it is straight 1~3 electrode is fixed with section.
6. the Multi-electrode renal artery ablation catheter as described in claim 1, it is characterised in that the skeleton of the adjustable diameter is from institute State a diameter of 3~10mm that adjustable bent catheter sheath discharges rear straight section.
7. the Multi-electrode renal artery ablation catheter as described in claim 1, it is characterised in that the adjustable bent catheter sheath is two-tube Cavity configuration a, tube chamber leads to ablation catheter, and a tube chamber leads to traction fiber.
8. the Multi-electrode renal artery ablation catheter as described in claim 7, it is characterised in that leading in the adjustable bent catheter sheath Draw the end that one end is fixed on adjustable bent catheter sheath, the other end is fixed on the traction fiber fixture of function handle.
9. the Multi-electrode renal artery ablation catheter as described in claim 1, it is characterised in that be provided with and disappear on the function handle Melt equipment interface, each electrode is connected by wire with the ablation apparatus interface, and the ablation apparatus interface passes through connecting line The connection with RF ablation instrument can be achieved, by transmission of radio-frequency energy to each electrode.
10. the Multi-electrode renal artery ablation catheter as described in claim 1, it is characterised in that the electrode is connected with TEMP Device, is connected by wire with the ablation apparatus interface, and the ablation apparatus interface can be realized and RF ablation by connecting line The connection of instrument, the temperature signal of each electrode is included on RF ablation instrument.
CN201210233475.6A 2012-07-07 2012-07-07 Multi-electrode renal artery ablation catheter Expired - Fee Related CN103519882B (en)

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CN103519882B true CN103519882B (en) 2017-09-12

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CN107440786A (en) * 2016-06-01 2017-12-08 四川锦江电子科技有限公司 A kind of ablation catheter and ablating device of reconfigurable section
CN106901831A (en) * 2017-03-23 2017-06-30 深圳市惠泰医疗器械有限公司 The arteria renalis stimulates ablating electrode conduit
CN108784825A (en) * 2017-05-05 2018-11-13 上海安通医疗科技有限公司 A kind of electrode adherence method of detection radio frequency ablation catheter
CN111887979B (en) * 2020-08-24 2025-04-29 绍兴梅奥心磁医疗科技有限公司 A radiofrequency ablation catheter and sheath linkage control device
CN114681038A (en) * 2020-12-31 2022-07-01 杭州德诺电生理医疗科技有限公司 Ablation device and ablation system
CN114271928B (en) * 2021-12-26 2023-07-28 上海安通医疗科技有限公司 Combined ablation catheter applicable to radial artery
CN114424971A (en) * 2022-01-26 2022-05-03 上海鑫律通生命科技有限公司 Spline basket ablation catheter capable of being bent in two directions
CN114557767A (en) * 2022-02-10 2022-05-31 上海安通医疗科技有限公司 Ablation catheter

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