CN103518729B - Insecticidal acaricidal composition and application thereof - Google Patents
Insecticidal acaricidal composition and application thereof Download PDFInfo
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- CN103518729B CN103518729B CN201210227729.3A CN201210227729A CN103518729B CN 103518729 B CN103518729 B CN 103518729B CN 201210227729 A CN201210227729 A CN 201210227729A CN 103518729 B CN103518729 B CN 103518729B
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- 239000002552 dosage form Substances 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- 239000003337 fertilizer Substances 0.000 description 1
- 230000004907 flux Effects 0.000 description 1
- WSFSSNUMVMOOMR-UHFFFAOYSA-N formaldehyde Substances O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- RBNPOMFGQQGHHO-UHFFFAOYSA-N glyceric acid Chemical compound OCC(O)C(O)=O RBNPOMFGQQGHHO-UHFFFAOYSA-N 0.000 description 1
- 201000003872 goiter Diseases 0.000 description 1
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 description 1
- 230000009916 joint effect Effects 0.000 description 1
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 description 1
- 239000012263 liquid product Substances 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 159000000003 magnesium salts Chemical class 0.000 description 1
- 239000012046 mixed solvent Substances 0.000 description 1
- XGXNTJHZPBRBHJ-UHFFFAOYSA-N n-phenylpyrimidin-2-amine Chemical group N=1C=CC=NC=1NC1=CC=CC=C1 XGXNTJHZPBRBHJ-UHFFFAOYSA-N 0.000 description 1
- 210000004681 ovum Anatomy 0.000 description 1
- 125000006353 oxyethylene group Chemical group 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 229910052625 palygorskite Inorganic materials 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 239000005011 phenolic resin Substances 0.000 description 1
- 229920001568 phenolic resin Polymers 0.000 description 1
- WRAQQYDMVSCOTE-UHFFFAOYSA-N phenyl prop-2-enoate Chemical class C=CC(=O)OC1=CC=CC=C1 WRAQQYDMVSCOTE-UHFFFAOYSA-N 0.000 description 1
- 229920005646 polycarboxylate Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229920002503 polyoxyethylene-polyoxypropylene Polymers 0.000 description 1
- 230000003449 preventive effect Effects 0.000 description 1
- 238000003672 processing method Methods 0.000 description 1
- QQONPFPTGQHPMA-UHFFFAOYSA-N propylene Natural products CC=C QQONPFPTGQHPMA-UHFFFAOYSA-N 0.000 description 1
- 125000004805 propylene group Chemical group [H]C([H])([H])C([H])([*:1])C([H])([H])[*:2] 0.000 description 1
- 150000004040 pyrrolidinones Chemical class 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 235000021003 saturated fats Nutrition 0.000 description 1
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 description 1
- 235000010413 sodium alginate Nutrition 0.000 description 1
- 239000000661 sodium alginate Substances 0.000 description 1
- 229940005550 sodium alginate Drugs 0.000 description 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
- 235000017557 sodium bicarbonate Nutrition 0.000 description 1
- 239000001488 sodium phosphate Substances 0.000 description 1
- 229910000162 sodium phosphate Inorganic materials 0.000 description 1
- 159000000000 sodium salts Chemical class 0.000 description 1
- PYODKQIVQIVELM-UHFFFAOYSA-M sodium;2,3-bis(2-methylpropyl)naphthalene-1-sulfonate Chemical compound [Na+].C1=CC=C2C(S([O-])(=O)=O)=C(CC(C)C)C(CC(C)C)=CC2=C1 PYODKQIVQIVELM-UHFFFAOYSA-M 0.000 description 1
- 239000001587 sorbitan monostearate Substances 0.000 description 1
- 235000011076 sorbitan monostearate Nutrition 0.000 description 1
- 229940035048 sorbitan monostearate Drugs 0.000 description 1
- 230000007480 spreading Effects 0.000 description 1
- 238000003892 spreading Methods 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 238000007619 statistical method Methods 0.000 description 1
- 229910021653 sulphate ion Inorganic materials 0.000 description 1
- HTSABYAWKQAHBT-UHFFFAOYSA-N trans 3-methylcyclohexanol Natural products CC1CCCC(O)C1 HTSABYAWKQAHBT-UHFFFAOYSA-N 0.000 description 1
- ZIBGPFATKBEMQZ-UHFFFAOYSA-N triethylene glycol Chemical compound OCCOCCOCCO ZIBGPFATKBEMQZ-UHFFFAOYSA-N 0.000 description 1
- 239000013638 trimer Substances 0.000 description 1
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 230000001018 virulence Effects 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention belongs to the field of pesticides, and discloses an insecticidal acaricidal composition containing an active component A and an active component B, wherein the active component A is selected from the following compounds disclosed in the specification; the active component B is selected from tetronic acid (tetronic acid/tetramic acid derivative) insecticides and acaricides; the tetronic acid insecticides and acaricides comprise spirodiclofen, spiromesifen, spirotetramat or the like; and the weight ratio of the active component A to the active component B is 1:99-99:1. The composition has obvious synergistic action, widens the insecticidal spectrum, and reduces the pesticide consumption; and the pests can not easily generate drug resistance, and thus, the composition can be used for preventing and treating multiple pests and acarids on multiple crops.
Description
Technical field
The invention belongs to pesticide field, relate to a kind of synergistic complex composition that contains two kinds of active components, be specifically related to a kind of desinsection, miticide composition and application thereof.
Background technology
In the real process of agricultural production, using chemical agent is the most effectively one of means of control plant pest.Yet the problem the most easily producing by Agro-chemicals control insect pest is insect, evil mite drug-fast generation, use single pest control with insecticide, miticide continuously simultaneously for a long time high dose, easily cause the series of problems such as residual, environmental pollution of medicament.Reasonably pest control with insecticide, miticide is composite or be mixed and have the desinsection of expansion, kill mite spectrum, improve control efficiency, extend the optimum period for applying fertilizer, reduce dosage, reduce poisoning, reduce residual, delay the positive features such as insect, the evil drug-fast generation of mite and development, it is one of the effective method the most addressing the above problem that Insecticidal and acaricidal agent is mixed.
Chinese invention patent CN101906075A discloses the purposes of a kind of E-type phenyl acrylates compounds containing substituted anilino pyrimidine group and Control pests thereof, evil mite, wherein compound 9 can be used for preventing and treating various pests, evil mite, especially mite class is had to outstanding control efficiency, be subject to the extensive attention of industry.This structural formula of compound is as follows:
Known tetronic acid class (tetronic acid/tramm acid derivative class) desinsection, miticide has 3 kinds at present: spiral shell mite ester (spirodiclofen), Spiromesifen (spiromesifen) and spiral shell worm ethyl ester (spirotetramat), all there is good desinsection and acaricidal activity, all effective to all vegetative stages of phytophagous mites, all effective to the ovum of aleyrodid class and mite class and adult, beneficial insect is had no adverse effects, its mechanism of action is for stoping the effect (this kind of enzyme helps synthetic important fatty acid in the process of growth of mite) of acetyl-CoA carboxylase, mechanism of action is unique, using dosage is 50-200g ai/hm
2.
Different cultivars composition carries out composite, may produce some unexpected technique effect, is also control resistant insect, the very common method of evil mite.Yet, have no so far the report of above-claimed cpd 9 and tetronic acid class Insecticidal and acaricidal agent complex composition.
Summary of the invention
The object of the invention is to develop binary desinsection, the miticide composition of the disclosed compound 9 of a kind of CN101906075A of containing and tetronic acid class Insecticidal and acaricidal agent, to improve preventive effect, reduce dosage, solve desinsection simultaneously, kill that the resistance that the long-term use of mite single dose may bring occurs, degradation problem under drug effect.
By research, find, compound 9 has very outstanding effect with the composite control to insect, evil mite under suitable ratio of tetronic acid class (tetronic acid/tramm acid derivative class) Insecticidal and acaricidal agent, thereby has completed the present invention.
Technical scheme of the present invention is as follows:
Desinsection, a miticide composition, contain A, two kinds of active components of B,
Component A is selected from compound 9, and structural formula is as follows:
B component is selected from tetronic acid class Insecticidal and acaricidal agent, and described tetronic acid class Insecticidal and acaricidal agent is selected from spiral shell mite ester, Spiromesifen or spiral shell worm ethyl ester;
Ratio of weight and number between A, two kinds of active components of B is 1:99 to 99:1.
The comparatively preferred technical scheme of the present invention is:
In described desinsection, miticide composition, component A is selected from compound 9; B component is selected from spiral shell mite ester, Spiromesifen or spiral shell worm ethyl ester; Ratio of weight and number between A, B two active components is 1:50 to 50:1.
The further preferred technical scheme of the present invention is:
In described desinsection, miticide composition, component A is selected from compound 9; B component is selected from spiral shell worm ethyl ester; Ratio of weight and number between A, two kinds of active components of B is 1:10 to 10:1; Or
Component A is selected from compound 9; B component is selected from spiral shell mite ester; Between A, two kinds of active components of B, ratio of weight and number is 1:1 to 10:1.
Desinsection of the present invention, miticide composition have obvious synergistic effect.Indoor biological activity determination result demonstration, compound 9 is composite in suitable proportion with spiral shell mite ester, Spiromesifen or spiral shell worm ethyl ester, can greatly improve the activity to Tetranychus cinnabarinus; Equally the harmful mite of Acaricides generation resistance is had to higher activity.
In desinsection of the present invention, miticide composition, the total content of active component by weight (lower same), between 0.5%～95%, is preferably between 1%～85%.According to different preparation types, active component total content scope is different.Conventionally, in liquid preparation, the total content of active component, between l～70%, is preferably 5～50%; In solid pharmaceutical preparation, the total content of active component, between 5～85%, is preferably 10～80%;
In desinsection of the present invention, miticide composition, at least contain a kind of surfactant, the dispersion of active component in water while being beneficial to use.The total content of surfactant is between 5～30%, and surplus is solid or liquid-carrier.Desinsection of the present invention, the selected surfactant of miticide composition are known in those skilled in the art, as: one or more in dispersant, wetting agent, binding agent, defoamer, stabilizing agent or emulsifier.According to different dosage form, in preparation, can also contain antifreeze known in those skilled in the art, thickener, disintegrant etc.
Desinsection of the present invention, miticide composition can be by user before use through dilution or directly uses.Its preparation can be prepared by common processing method known in those skilled in the art, after being about to active substance and mixing with liquid flux or solid packing, then add surfactant as one or more in dispersant, wetting agent, binding agent, defoamer, stabilizing agent etc.
Desinsection of the present invention, miticide composition, can be processed into acceptable any formulation on agricultural chemicals on demand, and wherein more preferably formulation is: missible oil, suspending agent, water dispersible granules, aqueous emulsion, microemulsion, soluble liquid, wetting powder or oil-suspending agent.
Desinsection of the present invention, miticide composition, comprise following constituent content while making missible oil: active component A l～50%, active component B l～50%, emulsifier 2～20%, synergist 0～20%, cosolvent 0～20%, solvent complement to 100%.By active component A and B add in solvent, dissolve completely after, add cosolvent if desired, then after adding emulsifier, synergist etc. to stir, become the oily liquids of transparent and homogeneous, make the missible oil product of the present composition.
Desinsection of the present invention, miticide composition, comprise following constituent content while making suspending agent: active component A l～50%, active component B l～50%, dispersant 2～10%, wetting agent 2～10%, defoamer 0.1～1%, thickener 0.1～2%, binding agent 0.1～2%, antifreeze 0.1～8%, water add to 100%.Dispersant, wetting agent, defoamer, thickener, binding agent, antifreeze, water in above-mentioned formula are mixed through high speed shear, add active component A and B, in ball mill, ball milling is 2～3 hours, makes diameter of particle all below 5um, makes the suspending agent product of the present composition.
Desinsection of the present invention, miticide composition, comprise following constituent content while making water dispersible granules: active component A l～60%, active component B l～60%, dispersant 3～12%, wetting agent l～8%, disintegrant l～10%, binding agent l～8%, solid carrier complement to 100%.Active component A is obtained to the particle diameter needing through air-flow crushing together with B, dispersant, wetting agent, disintegrant, binding agent, solid carrier etc., then add other auxiliary agents such as binding agent, obtain the materials of granulating.By item quantitatively send in fluidized bed granulation dryer through granulation and dry after, make water dispersible granules product of the present invention.
Desinsection of the present invention, miticide composition, comprise following constituent content while making aqueous emulsion: active component A l～40%, active component B l～40%, solvent 0～30%, emulsifier l～15%, antifreeze 0～10%, thickener 0.1～2%, defoamer 0.0l～2%, water complement to 100%.Active component A and B, solvent, emulsifier are added together, make to be dissolved into even oil phase; Water, antifreeze, thickener, defoamer are mixed, become homogeneous water.Under high-speed stirred, water is added to oil phase, make aqueous emulsion product of the present invention.
Desinsection of the present invention, miticide composition, comprise following constituent content while making microemulsion: active component A l～40%, active component B l～40%, solvent 0～30%, emulsifier 3～20%, cosolvent 0～20%, antifreeze 0～10%, water complements to 100%.Active component A and B are dissolved in the homogenizer that solvent and cosolvent are housed, after emulsifier, antifreeze, water being joined in the homogenizer that above-mentioned solution is housed, give strong mixing and homogenize, finally obtain the as clear as crystal microemulsion product of the present invention of outward appearance.
Desinsection of the present invention, miticide composition, comprise following constituent content while making soluble liquid: active component A 1～50%, active component B 1～50%, emulsifier 1～20%, synergist 1-10%, organic solvent complement to 100%.Active component A and B, organic solvent, emulsifier, synergist etc. are mixed, become transparent and homogeneous liquid, make the soluble liquid product of the present composition.
Desinsection of the present invention, miticide composition, comprise following constituent content while making wetting powder: active component A 1～60%, active component B 1～60%, dispersant 2～10%, wetting agent 2～10%, solid carrier complement to 100%.Active components A and B, dispersant, wetting agent, solid carrier are mixed, in blender, mix, after airslide disintegrating mill is pulverized, mix again, can be made into wetting powder product of the present invention.
Desinsection of the present invention, miticide composition, comprise following constituent content while making oil-suspending agent: active component A 1～50%, active component B 1～50%, emulsifier 1～20%, cosolvent 1～20%, dispersant 0～0.3%, wetting agent 0.2～1%, solvent complement to 100%.Active component A and B, emulsifier, dispersant, solvent, cosolvent, wetting agent are added to sand milling in sand mill, until particle diameter is qualified, make the oil-suspending agent product of the present composition.
Described dispersant is selected from, but be not limited to: alkylnaphthalene sulfonate, two (alkyl) naphthalenesulfonate formaldehyde condensation compound, naphthalene sulfonic acid-formaldehyde condensation product, aryl phenol polyoxyethylene succinate sulfonate, octylphenol polyethylene oxyethylene group ether sulfate, polycarboxylate, lignosulfonates, alkylphenol polyoxyethylene formaldehyde condensation products sulphate, alkyl benzene sulfonate calcium salt, naphthalene sulfonic acid-formaldehyde condensation product sodium salt, alkylphenol polyoxyethylene, aliphatic acid polyethenoxy ether, polyoxyethylene carboxylate, one or more in fatty acid glyceride APEO.
Described wetting agent is selected from but is not limited to: lauryl sodium sulfate, neopelex, Nekal BX, washing powder, agriculture breast 2000# series, wetting and penetrating agent F, wetting agent T, spaonin powder, tea are withered, one or more in silkworm excrement, sldium lauryl sulfate, alkylnaphthalene sulfonate, alkylphenol ethoxylate, polyoxyethylene triphenylethylene phosphenylic acid salt, soapberry powder.
Described binding agent is selected from but is not limited to: one or more in gum Arabic, xanthans, sodium phosphate trimer, phenolic resins, sodium alginate, cyclodextrin, methylcellulose, PAA, polyvinylpyrrolidone, crospolyvinylpyrrolidone, polyethylene glycol, polyvinyl alcohol.
Described defoamer is selected from but is not limited to: silicone, C
8～10aliphatic alcohols, C
10～20one or more in saturated fat acids (as capric acid) and acid amides, silicone oil, silicone compound, polyoxyethylene glycerol ether.
Described emulsifier is selected from, but be not limited to: agriculture breast 500#(alkyl benzene calcium sulfonate), 0P series phosphate (polyoxyethylene nonylphenol ether phosphate), styrene polyoxyethylene ether ammonium sulfate salt, alkyl biphenyl ether disulfonic acid magnesium salts, triethanolamine salt, agriculture breast 400#(benzyl dimethyl phenol polyoxy ethyl ether), agriculture breast 600#(phenyl phenol polyoxy ethyl ether phosphate), Nongru-700 #(alkylphenol-formaldehyde resin polyoxy ethyl ether), agriculture breast 36#(phenethyl fluosite polyoxy ethyl ether), agriculture breast 1600#(phenethyl phenol polyoxy ethyl polypropylene-base ether), ethylene oxide-propylene oxide block copolymer, By series (castor oil polyoxyethylene ether), agriculture breast 33#(alkylaryl polyoxyethylene polyoxypropylene ether), agriculture breast 34#(alkylaryl polyoxyethylene poly-oxygen propylene aether), sapn series (sorbitan monostearate), tween series (sorbitan fatty acid ester APEO), AE0 series (fatty alcohol-polyoxyethylene ether), calcium dodecyl benzene sulfonate and aliphatic acid polyethenoxy ether, alkylphenol polyoxyethylene sulfosuccinate, styrylphenol polyoxyethylene ether, polyoxyethylene nonylphenol ether, aliphatic acid polyethenoxy base ester, one or more in polyoxyethylene aliphatic alcohol ether.
Described antifreeze is selected from: one or more in ethylene glycol, propane diols, glycerine, polyethylene glycol, diethylene glycol (DEG), triethylene glycol.
Described thickener is selected from: one or more in xanthans, CMC, hydroxyethylcellulose, methylcellulose, Magnesiumaluminumsilicate, polyvinyl alcohol.
Described disintegrant is selected from: one or more in bentonite, urea, ammonium sulfate, glucose, aluminium chloride, citric acid, succinic acid, sodium bicarbonate.
Described solvent is selected from: one or more in toluene, dimethylbenzene, methyl alcohol, ethanol, acetone, ether, cyclohexanone, n-butanol, isopropyl alcohol, vegetable oil, dimethyl formamide, dimethyl sulfoxide (DMSO), acetonitrile, polyethylene glycol, pyrrolidones, N-chain alkyl pyrrolidones, biodiesel, diesel oil, turpentine oil, solvent naphtha, water or more than one mixed solvents forming with arbitrary proportion;
Described solid carrier is selected from: one or more in kaolin, diatomite, bentonite, attapulgite, white carbon, starch, precipitated calcium carbonate.
Described synergist is selected from: any one in organic silicon pesticide synergist, organic silicon pesticide bleeding agent spreading agent, agricultural organic silicon pesticide synergist, azone.
Desinsection of the present invention, miticide composition, can be used for preventing and treating insect, evil mite or urban health insect on fruit tree, vegetables, ornamental plants, tea, cotton, cereal crop; Especially, desinsection of the present invention, miticide composition, especially can be used in the application of evil mite on control control crops, particularly on control crops oranges and tangerines, cotton, apple, flowers or vegetables etc., do harm in the application of mite, especially aspect the evil mites such as control two spotted spider mite, blister mite, tarsonemid, yellow tea mite, goitre mite, Tetranychus cinnabarinus or Tetranychus urticae; Therefore, technical scheme of the present invention also comprises the purposes for the preparation of farm killing mite agent medicine by miticide composition of the present invention.
Desinsection of the present invention, miticide composition, can effective dose impose on the insect/evil mite and/or its habitat that needs to control.
Desinsection of the present invention, miticide composition have the following advantages: the A 1, being mixed, two kinds of active components of B have the different mechanism of action, can delay the generation of pest resistance to insecticide.2, reduce agricultural chemicals usage amount, reduced the residual quantity of agricultural chemicals on crop, strengthened the friendly to environment.3,, after A, two kinds of active components of B are mixed, improved quick-acting and the lasting effect of single dose; Expanded insecticidal spectrum, multiple sucking pest, evil mite have been had to special efficacy.
Embodiment
Following examples are used for describing in detail the present invention, so that further understand the present invention.Active component A is selected from the disclosed compound 9 of Chinese invention patent CN101906075A, self-control; Active component B and other raw materials are commercial goods.In formulation Example, after active component folding hundred, be metered into, each component is measured by weight percentage.
Formulation Example
Embodiment 1:20% compound 9 spiral shell mite emulsifiable concentrates
Compound 9 10%, spiral shell mite ester 10%, calcium dodecyl benzene sulfonate 2%, agriculture breast 600#3%, dimethylbenzene supply 100%.The method of above raw material being prepared routinely to missible oil mixes, and can make 20% compound 9 spiral shell mite emulsifiable concentrates.
Embodiment 2:10% compound 9 spiral shell mite emulsifiable concentrates
Compound 9 9%, spiral shell mite ester 1%, calcium dodecyl benzene sulfonate 2%, agriculture breast 500#3%, agriculture breast 33#2%, dimethylbenzene supply 100%.The method of above raw material being prepared routinely to missible oil mixes, and can make 10% compound 9 spiral shell mite emulsifiable concentrates.
Embodiment 3:10% compound 9 spiral shell mite ester suspending agents
Compound 9 5%, spiral shell mite ester 5%, aryl phenol polyoxyethylene succinate sulfonate 5%, soapberry powder 5%, silicone compound 0.1%, polyvinylpyrrolidone 1%, propane diols 1.8%, water complement to 100%.The method of above raw material being prepared routinely to suspending agent mixes, and can make 10% compound 9 spiral shell mite ester suspending agents.
Embodiment 4:15% compound 9 spiral shell mite ester suspension emulsions
Compound 9 10%, spiral shell mite ester 5%, sodium lignin sulfonate 8%, JFC 3%, agriculture breast 600#3%, xanthans 5%, water complement to 100%.The method of above raw material being prepared routinely to suspending agent mixes, and can make 15% compound 9 spiral shell mite ester suspending agents.
Embodiment 5:20% compound 9 spiral shell worm ethyl ester suspension emulsions
Compound 9 10%, spiral shell worm ethyl ester 10%, aryl phenol polyoxyethylene succinate sulfonate 6%, tea are withered 4%, polyvinylpyrrolidone 1.8%, agriculture breast 1600#4.2%, glycerine 1.8%, C
8～10aliphatic alcohols 0.8%, water complement to 100%.The method of above raw material being prepared routinely to suspending agent mixes, and can make 20% compound 9 spiral shell worm ethyl ester suspending agents.
Embodiment 6:60% compound 9 spirodiclofen water dispersible granules
Compound 9 30%, spiral shell mite ester 30%, sodium lignin sulfonate 6%, lauryl sodium sulfate 4%, ammonium sulfate 5%, precipitated calcium carbonate complement to 100%.Above raw material is prepared routinely to the method for water dispersible granules and fully mixed, be crushed to certain fineness, can make 60% compound 9 spirodiclofen water dispersible granules.
Embodiment 7:40% compound 9 spirodiclofen water dispersible granules
Compound 9 30%, spiral shell mite ester 10%, naphthalene sulfonic acid-formaldehyde condensation product 10%, lauryl sodium sulfate 5%, ammonium sulfate 15%, potter's clay complement to 100%.Above raw material is prepared routinely to the method for water dispersible granules and fully mixed, be crushed to certain fineness, can make 40% compound 9 spirodiclofen water dispersible granules.
Embodiment 8:20% compound 9 spirodiclofen water emulsions
Compound 9 10%, spiral shell mite ester 10%, 3-methyl cyclohexanol ketenes 4%, 0P series 7%, propyl alcohol 3%, ethylene glycol 2.8%, CMC 1.3%, C
8～10aliphatic alcohols 0.2%, water complements to 100%.Above raw material is prepared routinely to the method for aqueous emulsion, can be made 20% compound 9 spirodiclofen water emulsions.
Embodiment 9:20% compound 9 spirodiclofen microemulsions
Compound 9 10%, spiral shell mite ester 10%, tween series 4%, agriculture breast 500#3%, phenethyl phenol polyethenoxy ether phosphate 5%, xanthans 2%, ethylene glycol 5%, silicone oil 0.4%, water complements to 100%.Above raw material is prepared routinely to the method for microemulsion, can be made 20% compound 9 spirodiclofen microemulsions.
Embodiment 10:10% compound 9 spiral shell mite ester soluble liquids
Compound 9 5%, spiral shell mite ester 5%, phenethyl phenol polyethenoxy ether 15%, AEO series 5%, cellosolve 20%, dimethyl formamide complement to 100%.Prepare routinely the method for soluble liquid, compound 9 and spiral shell mite ester are dissolved in solvent, add surfactant and other components, in enamel reaction still or stainless steel stirred tank, stir, can make 10% compound 9 spiral shell mite ester soluble liquids.
Embodiment 11:25% compound 9 spiral shell worm ethyl ester soluble liquids
Compound 9 20%, spiral shell worm ethyl ester 5%, phenethyl phenol polyethenoxy ether 5%, AEO series 10%, cyclohexanone 5%, dimethyl formamide complement to 100%.Prepare routinely the method for soluble liquid, compound 9 and spiral shell worm ethyl ester are dissolved in solvent, add surfactant and other components, in enamel reaction still or stainless steel stirred tank, stir, can make 25% compound 9 spiral shell worm ethyl ester soluble liquids.
Embodiment 12:20% compound 9 spiral shell mite ester wetting powders
Compound 9 10%, spiral shell mite ester 10%, lignosulfonates 5%, soapberry powder 6%, bentonite complement to 100%.Above raw material is prepared routinely to the method for wetting powder and fully mixed, be crushed to certain fineness, can make 20% compound 9 spiral shell mite ester wetting powders.
Embodiment 13:10% compound 9 spiral shell mite ester oil suspending agents
Compound 9 5%, spiral shell mite ester 5%, sodium lignin sulfonate 5%, bentonite 3%, xanthans 2%, organic silicone 3%, castor oil complement to 100%.Above raw material is prepared routinely to the method for oil-suspending agent, each component is put into and after sand milling still grinds, sent into mixer for well-distribution and mix, can make 10% compound 9 spiral shell mite ester oil suspending agents.
Embodiment 14:15% compound 9 spiral shell mite ester oil suspending agents
Compound 9 10%, spiral shell mite ester 5%, sodium lignin sulfonate 6%, bentonite 3%, xanthans 2%, organic silicone 4%, castor oil complement to 100%.Above raw material is prepared routinely to the method for oil-suspending agent, each component is put into and after sand milling still grinds, sent into mixer for well-distribution and mix, can make 15% compound 9 spiral shell mite ester oil suspending agents.
Embodiment 15:20% compound 9 spiral shell worm ethyl ester oil-suspending agents
Compound 9 10%, spiral shell worm ethyl ester 10%, sodium lignin sulfonate 6%, bentonite 3%, xanthans 2%, organic silicone 4%, castor oil complement to 100%.Above raw material is prepared routinely to the method for oil-suspending agent, each component is put into and after sand milling still grinds, sent into mixer for well-distribution and mix, can make 20% compound 9 spiral shell worm ethyl ester oil-suspending agents.
Indoor biological activity determination embodiment
Embodiment 16: compound 9 is mixed Tetranychus cinnabarinus synergism determination is tested with spiral shell mite ester, spiral shell worm ethyl ester
For trying target: Tetranychus cinnabarinus [Tetranychus cinnabarinus(boisduval)] one-tenth mite, the sensitive strain of indoor feeding.
Liquid preparation: according to different tests needs, accurately take respectively test sample with electronic analytical balance, former medicine is with acetone solution, then becomes the serial liquid of tool finite concentration gradient according to experimental scheme dose dilution with the water that contains 0.1% Tween 80.
Test method: adopt potted plant seedling spray-on process to measure the activity size that Tetranychus cinnabarinus is become to mite.First Tetranychus cinnabarinus of the same size is become mite to receive on the Tolerance of Kidney Bean Seedlings blade in first pair of open and flat phase of true leaf, after becoming mite stable, count radix; Then press the order even spraying of experimental scheme from low dosage to high dose, every strain 1.5mL, every processing repeats for 3 times, separately establishes blank.
Examination material after processing is placed in observation ward, and the temperature of observation ward, humidity, illumination are adjustable as required.72 hours " Invest, Then Investigate " mite numbers dead, alive.The actual measurement lethality of calculating each processing with abbott formula, result of the test is in Table 1.
Mixed effect assessment adopts Bliss method, and Bliss thinks according to the independent joint action concept of its proposition, and theoretical lethality P during Mixture Use of Insecticides can calculate with following formula:
P=Pm+Pn（1-Pm）
Pm is the actual measurement lethality (%) of the first active component target when concentration is m; Pn is the actual measurement lethality (%) of the second active component working concentration target while being n.
If the actual of two kinds of active components target after mixing with finite concentration is greater than theoretical lethality P, to judge that the mixing use under setting concentration of two kinds of active components has synergistic effect, otherwise be antagonism, result of the test is in Table 1.
Table 1 compound 9 is mixed to Tetranychus cinnabarinus synergism determination result with spiral shell mite ester, spiral shell worm ethyl ester
Embodiment 17: compound 9 is mixed to the indoor joint toxicity measuring test of Tetranychus cinnabarinus with spiral shell mite ester
For trying target: Tetranychus cinnabarinus [Tetranychus cinnabarinus(boisduval)] one-tenth mite, the sensitive strain of indoor feeding.
Liquid preparation: according to different tests needs, accurately take respectively test sample with electronic analytical balance, former medicine is with acetone solution, then becomes the serial liquid of tool finite concentration gradient according to experimental scheme dose dilution with 0.1% Tween 80 water.
Test method: adopt potted plant seedling spray-on process to measure the activity size that Tetranychus cinnabarinus is become to mite.First Tetranychus cinnabarinus of the same size is become mite to receive on the Tolerance of Kidney Bean Seedlings blade in first pair of open and flat phase of true leaf, after becoming mite stable, count radix; Then press the order even spraying of experimental scheme from low dosage to high dose, every strain 1.5mL, every processing repeats for 3 times, separately establishes blank.
Examination material after processing is placed in observation ward, and the temperature of observation ward, humidity, illumination are adjustable as required.72 hours " Invest, Then Investigate " mite numbers dead, alive.By abbott formula calculation correction lethality, with DPS data processing software, carry out statistical analysis, obtain each for examination single dose and mixed virulence regression equation formula, the LC of variant proportioning
50value and 95% confidence limit, then use Sun Yunpei (Suny-p) method to calculate the co-toxicity coefficient of each proportioning, evaluate mixed effect, result of the test is in Table 2.
The co-toxicity coefficient of mixture (CTC value) calculates by following formula:
In formula: ATI-mixture actual measurement toxicity index; The LC of S-standard medicament
50; The LC of M-mixture
50.
TTI=TIA×PA+TIB×PB
In formula: the theoretical toxicity index of TTI-mixture; TIA-A medicament toxicity index; The percentage composition of PA-A medicament in mixture; TIB-B medicament toxicity index; The percentage composition of PB-B medicament in mixture.
In formula: CTC-co-toxicity coefficient; ATI-mixture actual measurement toxicity index; The theoretical toxicity index of TTI-mixture.
The co-toxicity coefficient of built agent (CTC): CTC >=120 show as synergistic effect; CTC≤80 show as antagonism; 80<CTC<120 shows as summation action.
Table 2 compound 9 is mixed to the indoor joint toxicity measuring of Tetranychus cinnabarinus with spiral shell mite ester
Above indoor biometrics result of the test shows, compound 9 is mixed and has obvious synergistic effect with tetronic acid class Insecticidal and acaricidal agent, 1:1 to 10:1 for examination ratio under, compound 9 is mixed obvious to Tetranychus cinnabarinus synergistic effect with spiral shell mite ester.
The explanation of above embodiment is just for helping to understand method of the present invention and core concept thereof.It should be pointed out that for those skilled in the art, under the premise without departing from the principles of the invention, can also carry out some improvement and modification to the present invention, these improvement and modification also fall in the protection domain of the claims in the present invention.In sum, the present composition has advantages of that quick-acting is good, the lasting period is long, and environmental pollution is few, is difficult for producing poisoning, can be widely used in agriculture field.
Claims (7)
1. desinsection, a miticide composition, contain A, two kinds of active components of B,
Component A is selected from compound 9, and structural formula is as follows:
B component is selected from tetronic acid class Insecticidal and acaricidal agent, and described tetronic acid class Insecticidal and acaricidal agent is selected from spiral shell mite ester or spiral shell worm ethyl ester; The ratio of weight and number of A, B two active components is 1:50 to 50:1.
2. composition according to claim 1, is characterized in that: component A is selected from compound 9; B component is selected from spiral shell worm ethyl ester; The ratio of weight and number of A, B two active components is 1:10 to 10:1.
3. composition according to claim 2, is characterized in that: component A is selected from compound 9; B component is selected from spiral shell mite ester; The ratio of weight and number of A, B two active components is 1:1 to 10:1.
4. according to the composition described in any one of claim l～3, it is characterized in that: in composition, the accumulating weight content of active component is 0.5%-95%.
5. according to the composition described in any one of claim l～3, it is characterized in that: can make on demand missible oil, suspending agent, water dispersible granules, aqueous emulsion, microemulsion, soluble liquid, wetting powder or oil-suspending agent.
6. according to the composition described in claim l, it is characterized in that: for preventing and treating insect, evil mite or the urban health insect on fruit tree, vegetables, ornamental plants, tea, cotton, cereal crop.
7. composition according to claim 6, is characterized in that: for the preparation of the purposes of farm killing mite agent medicine.
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| CN104686521A (en) * | 2012-12-29 | 2015-06-10 | 陕西汤普森生物科技有限公司 | Anti-mite composition containing pyriminostrobin |
| CN103493831B (en) * | 2013-09-16 | 2015-12-02 | 陕西农心作物科技有限公司 | A kind of Pesticidal combination containing phonetic mite amine and tetronic acid insecticides |
| CN103719093A (en) * | 2013-12-18 | 2014-04-16 | 朱志宽 | Insecticide compound comprising pyriminostrobin and spirodiclofen |
| CN107711234A (en) * | 2017-08-02 | 2018-02-23 | 雷燕梅 | A kind of prevention and controls of citrus evil mite |
| CN107874334A (en) * | 2017-10-20 | 2018-04-06 | 芜湖皮皮鲁网络技术有限公司 | Main broadcaster protects neck and preparation method thereof with degerming |
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| CN102204549A (en) * | 2011-05-24 | 2011-10-05 | 青岛海利尔药业有限公司 | Insecticidal composition containing spirotetramat and fenpyroximate |
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Effective date of registration: 20160214 Address after: 110021 Liaodong Road, Tiexi District, Liaoning, No. 8-1, No. Patentee after: SHENYANG SINOCHEM PESTICIDE CHEMICAL RESEARCH AND DEVELOPMENT CO., LTD. Address before: 100031 Beijing, Xicheng District, the door of the revitalization of the main street, No. 28 Patentee before: Sinochem Corporation Patentee before: Shenyang Research Institute of Chemical Industry |