CN103463568A - Traditional Chinese medicine for treating coronary heart disease - Google Patents
Traditional Chinese medicine for treating coronary heart disease Download PDFInfo
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Abstract
本发明公开了一种治疗冠心病的中药，其是由下述重量份配比的原料制成：黄芪10份、党参8份、当归3份、桃仁3份、红花2份、麦冬3份、炙甘草6份、丹参7份、川芎3份、郁金4份、元胡3份、赤芍3份、生地3份、柴胡3份、枳壳2份、桔梗2份、川牛膝2份、生山楂3份、制何首乌5份、瓜蒌仁4份。本发明中药可有效地扩张动脉，增加缺血器官血流量，降低血液粘度，降血脂和抗动脉粥样硬化，改善心肌缺血、缺氧状态，并对损害的心脏有保护和治疗作用，从而缓解和治愈冠心病心绞痛病人的胸闷、胀痛、憋气、心慌等临床症状。The invention discloses a traditional Chinese medicine for treating coronary heart disease, which is prepared from the following raw materials in proportion by weight: 10 parts of astragalus, 8 parts of codonopsis, 3 parts of angelica, 3 parts of peach kernel, 2 parts of safflower, and 3 parts of Radix Ophiopogon japonicus 6 parts of Zhigancao, 7 parts of Salvia miltiorrhiza, 3 parts of Chuanxiong, 4 parts of Curcuma, 3 parts of Yuanhu, 3 parts of Chishao, 3 parts of Rehmannia, 3 parts of Bupleurum, 2 parts of Citrus aurantii, 2 parts of Campanulaceae, Sichuan beef 2 parts of knee, 3 parts of raw hawthorn, 5 parts of prepared Polygonum multiflorum, and 4 parts of Gualou Ren. The traditional Chinese medicine of the present invention can effectively expand arteries, increase blood flow of ischemic organs, reduce blood viscosity, lower blood fat and resist atherosclerosis, improve myocardial ischemia and hypoxia, and have protective and therapeutic effects on damaged hearts, thereby Relieve and cure clinical symptoms such as chest tightness, distending pain, suffocation, and palpitation in patients with coronary heart disease and angina pectoris.
Description
Technical field
The present invention relates to a kind of Chinese medicine for the treatment of coronary heart disease, belong to the field of Chinese medicines.
Background technology
Coronary heart disease is called for short coronary heart disease.Because lipid metabolism is undesired, the lipid calmness in blood, on the endarterium of otherwise smooth, occurs that at endarterium the lipid material of some similar medicated porridge samples is piled up the white speckle formed, and is called atherosclerotic lesion.These specklees gradually increase and cause lumen of artery narrow, and blood flow is obstructed, and cause heart ischemia, produce angina pectoris.Coronary heart disease is common clinically cardiovascular disease, along with the variation of modern way of life and dietary structure, and the aging of population, the prevalence of coronary heart disease constantly rises, and has become one of principal disease of harm humans health.The Etiological of coronary heart disease is coronary atherosclerosis, but atherosclerotic reason still imperfectly understands, and may be the result of many factors comprehensive function.Traditional Chinese Medicine is thought: coronary heart disease belongs to traditional Chinese medical science obstruction of qi in the chest and cardialgia category, due to the healthy energy virtual loss, caused, the blood stasis turbid with expectorant such as diet, feelings will, cold-evil, the stagnation of QI, cold coagulation numbness resistance heart arteries and veins, take that Danzhong or left chest are ictally felt oppressed, pain is as mainly facing a kind of deficiency in origin and excess in superficiality disease of performance.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine for the treatment of coronary heart disease.
The technology used in the present invention solution is:
A kind of Chinese medicine for the treatment of coronary heart disease, it is to be made by the raw material of following weight parts proportioning: 10 parts of the Radixs Astragali, 8 parts of Radix Codonopsis, 3 parts of Radix Angelicae Sinensis, 3 parts, Semen Persicae, 2 parts, Flos Carthami, 3 parts of Radix Ophiopogonis, 6 parts of Radix Glycyrrhizae Preparatas, 7 parts of Radix Salviae Miltiorrhizaes, 3 parts of Rhizoma Chuanxiongs, 4 parts of Radix Curcumaes, 3 parts of Rhizoma Corydalis, 3 parts of Radix Paeoniae Rubra, 3 parts, the Radix Rehmanniae, 3 parts of Radix Bupleuri, 2 parts of Fructus Aurantiis, 2 parts of Radix Platycodoniss, 2 parts of Radix Cyathulaes, 3 parts of Fructus Crataegi, 5 parts of Radix Polygoni Multiflori Preparatas, 4 parts of Semen Trichosanthiss.
Above-mentioned form of Chinese drug is said peroral dosage form on any pharmaceutics.
Preferably, described medicament is a kind of pill, by above-mentioned weight portion proportioning, takes 20 flavor crude drug, is ground into respectively fine powder, sieves, and mixes, and with water pill, is drying to obtain.
Pharmacology of the present invention and beneficial effect are:
Coronary heart disease belongs to the traditional Chinese medical science " thoracic obstruction ", " angina pectoris " category, cardinal symptom be with Danzhong or left chest ictally feel oppressed, pain, the lighter only feels uncomfortable in chest as stops up, breathes and owe freely, severe one has chest pain radiating to the back, backache radiating to the heart.Be due to the healthy energy virtual loss, due to caused, the blood stasis turbid with expectorant such as diet, feelings will, cold-evil, the stagnation of QI, cold coagulation numbness resistance heart arteries and veins, use treatment by Chinese herbs primary disease of the present invention for this reason, QI invigorating with Zhi Qiben, invigorate blood circulation to control its mark, reinforcing body resistance, eliminating pathogens.The Radix Astragali, Radix Codonopsis QI invigorating in side, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong, Radix Paeoniae Rubra, Semen Persicae, Flos Carthami, Fructus Crataegi blood circulation promoting and blood stasis dispelling, the Radix Cyathulae promoting blood circulation, blood stasis dispelling blood, and it is descending to draw blood stasis.The Semen Trichosanthis expectorant powder junction, join Radix Bupleuri, Radix Curcumae dispersing the stagnated live-QI to relieve the stagnation of QI, joins Radix Platycodonis, the circulation of qi promoting of Fructus Aurantii the chest stuffiness relieving, make the capable blood of gas, Rhizoma Corydalis promoting the circulation of QI to relieve pain, the product impairment of YIN of Radix Ophiopogonis, the anti-vital energy regualting and blood circulation-promoting of Radix Polygoni Multiflori Preparata, Radix Rehmanniae heat clearing and blood cooling, joining Radix Angelicae Sinensis again can blood enriching and dryness moistening, blood stasis dispelling blood and do not hinder fresh blood.The Radix Glycyrrhizae Preparata emergency, logical hundred arteries and veins are with coordinating the actions of various ingredients in a prescription.All medicines are harmonious; expansion artery effectively; increase the ischemia organic blood flow volume; reduce blood viscosity; blood fat reducing and atherosclerosis; improve myocardial ischemia, anaerobic condition, and the heart of infringement is had to protection and therapeutical effect, thereby alleviate and cure uncomfortable in chest, the distending pain of coronary disease with angina pectoris, the clinical symptoms such as feel suffocated, have palpitation.The result of study demonstration, Chinese medicine of the present invention can improve the curative effect of angina pectoris, is the more satisfactory medicine for the treatment of coronary heart disease.
Clinical observation:
1. data and method
1.1 physical data: choose in October, 2010-2012 coronary heart disease inpatient 120 examples in year October as the object of observation.By medical treatment group and the matched group of successively being divided at random, each 60 examples for the treatment of group and matched group.Treatment group man 31 examples, female's 29 examples; Age 38-72 year, average 60.5 ± 10.5 years old.Matched group man 32 examples, female's 28 examples; Age 40-75 year, average 61.2 ± 10.3 years old.
1.2 case diagnosis standard:
1.2.1 the clinical criteria in Western medicine diagnose standard reference International Society of Cardiology and association and World Health Organization's clinical name standardization associating special topic group report.
The standard of " new Chinese medicine guideline of clinical investigations " that 1.2.2 tcm diagnosis standard reference Ministry of Public Health is promulgated " the new Chinese medicine treatment thoracic obstruction (angina pectoris) guideline of clinical investigations ".
1.3 Therapeutic Method:
1.3.1 matched group gives sorbitrate 10mg, oral, day 3 times; Aspirin Enteric-coated Tablets 75mg, oral, day 1 inferior conventional therapy.
1.3.2, on the matched group basis, adding, treatment group uses treatment by Chinese herbs of the present invention.Oral meal, a 6g, one day twice, serve on one month.
1.3.3 observed content: all cases treatment front and back are capable resting electrocardiogram inspection, angina pectoris symptom, traditional Chinese medical science disease all.
1.4 curative effect determinate standard: observe the variation for the treatment of front and back curative effect to treat angina pectoris, Electrocardiographic curative effect, traditional Chinese medical science disease curative effect.Angina pectoris and ECG curative effect standard reference " curative effect to treat angina pectoris evaluation criteria " evaluation curative effect.Produce effects: chest pain disappears, and ECG ST section, T ripple recover normal; Effectively: all there are improvement in various degree in the frequency of chest pain, degree, time limit, before ECG ST section forces down, take a turn for the better, and two-way or inverted T ripple shoals; Invalid: chest pain symptom, ECG ST section, T ripple are substantially without changing.Traditional Chinese medical science disease efficacy assessment standard according to integration method be divided into produce effects, effective, invalid, increase the weight of.Total mark before total mark after therapeutic index=treatment/treatment * 100%.Produce effects: therapeutic index<0.33; Effectively: 0.33<therapeutic index<0.67; Invalid: 0.67<therapeutic index<1; Increase the weight of: therapeutic index 1.
1.5 statistical method the data computer SPSS10.0 statistical analysis software is processed, the classification ordinal data adopts the Ridit analyzing and processing, and the measurement data result is used
mean, adopt the t check, the test of difference of data be take P<0.05 as meaningful.
2. result
2.1 angina pectoris symptom curative effect treatment group is better than matched group, in Table 1.
Table 1 liang group angina pectoris symptom curative effect relatively
Annotate *: P<0.05
2.2 the ECG curative effect treatment group is better than matched group, in Table 2.
Table 2 liang group patient ECG curative effect relatively
Annotate *: P<0.05
2.3 tcm syndrome curative effect treatment group is better than matched group, in Table 3.
Table 3 liang group patient tcm syndrome curative effect relatively
Annotate *: P<0.01.
Result shows, treatment group all higher than matched group (P<0.05), illustrates that the treatment group curative effect is better than matched group aspect curative effect to treat angina pectoris, ECG curative effect, traditional Chinese medical science disease curative effect.
The specific embodiment
A kind of Chinese medicine for the treatment of coronary heart disease, choose the raw material of Chinese medicine of following weight proportioning:
Radix Astragali 10g, Radix Codonopsis 8g, Radix Angelicae Sinensis 3g, Semen Persicae 3g, Flos Carthami 2g, Radix Ophiopogonis 3g, Radix Glycyrrhizae Preparata 6g, Radix Salviae Miltiorrhizae 7g, Rhizoma Chuanxiong 3g, Radix Curcumae 4g, Rhizoma Corydalis 3g, Radix Paeoniae Rubra 3g, Radix Rehmanniae 3g, Radix Bupleuri 3g, Fructus Aurantii 2g, Radix Platycodonis 2g, Radix Cyathulae 2g, Fructus Crataegi 3g, Radix Polygoni Multiflori Preparata 5g, Semen Trichosanthis 4g.
The preparation method of above-mentioned Chinese medicine is as follows:
Above-mentioned 20 flavor crude drug by taking, be ground into respectively fine powder, then sieves, and mixes, and with water pill, is drying to obtain.
Above-mentioned Chinese medicine also can be brewed into decoction according to a conventional method.
Claims (3)
1. a Chinese medicine for the treatment of coronary heart disease, is characterized in that it is to be made by the raw material of following weight parts proportioning: 10 parts of the Radixs Astragali, 8 parts of Radix Codonopsis, 3 parts of Radix Angelicae Sinensis, 3 parts, Semen Persicae, 2 parts, Flos Carthami, 3 parts of Radix Ophiopogonis, 6 parts of Radix Glycyrrhizae Preparatas, 7 parts of Radix Salviae Miltiorrhizaes, 3 parts of Rhizoma Chuanxiongs, 4 parts of Radix Curcumaes, 3 parts of Rhizoma Corydalis, 3 parts of Radix Paeoniae Rubra, 3 parts, the Radix Rehmanniae, 3 parts of Radix Bupleuri, 2 parts of Fructus Aurantiis, 2 parts of Radix Platycodoniss, 2 parts of Radix Cyathulaes, 3 parts of Fructus Crataegi, 5 parts of Radix Polygoni Multiflori Preparatas, 4 parts of Semen Trichosanthiss.
2. a kind of Chinese medicine for the treatment of coronary heart disease according to claim 1, it is characterized in that: described medicament is said peroral dosage form on any pharmaceutics.
3. a kind of Chinese medicine for the treatment of coronary heart disease according to claim 2, it is characterized in that: described medicament is a kind of pill, by above-mentioned weight portion proportioning, takes 20 flavor crude drug, is ground into respectively fine powder, sieves, and mixes, and with water pill, is drying to obtain.
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Cited By (11)
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| CN103784888A (en) * | 2014-02-23 | 2014-05-14 | 曹小松 | Traditional Chinese medicine for treating coronary atherosclerotic heart disease caused by qi deficiency and blood stasis |
| CN104127652A (en) * | 2014-07-24 | 2014-11-05 | 孙苗苗 | Medicine for treating coronary heart disease |
| CN104288680A (en) * | 2014-09-29 | 2015-01-21 | 萧开伟 | Liver-protecting and heart-nourishing tablet and preparation method thereof |
| CN105477556A (en) * | 2015-12-30 | 2016-04-13 | 杨桂珍 | Medicine for treating myocardial infarction type coronary heart disease |
| CN105796789A (en) * | 2014-12-14 | 2016-07-27 | 张雪松 | Traditional Chinese medicine preparation for treating coronary heart disease |
| CN105816722A (en) * | 2016-05-10 | 2016-08-03 | 贾敏 | Traditional Chinese medicine preparation for treating coronary artery atherosclerotic heart disease |
| CN105998610A (en) * | 2016-05-30 | 2016-10-12 | 姚新亮 | Traditional Chinese medicinal composition for treating coronary heart disease and preparation method thereof |
| CN108096433A (en) * | 2017-12-31 | 2018-06-01 | 何江 | Treat Chinese medicinal capsule of Senile Coronary Heart Disease syndrome of blood stasis due to qi deficiency and preparation method thereof |
| CN108404037A (en) * | 2017-02-09 | 2018-08-17 | 林峰 | A kind of turbid Chinese medicine compositions of promoting blood circulation of the Wen Yanghua treating artery plaque |
| CN108992619A (en) * | 2017-06-07 | 2018-12-14 | 徐定清 | A kind of medicine pill of Guanxintong stasis of blood pellet |
| CN110292618A (en) * | 2018-03-21 | 2019-10-01 | 刘世民 | It is a kind of to treat cardiopathic Chinese medicine composition |
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Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103784888A (en) * | 2014-02-23 | 2014-05-14 | 曹小松 | Traditional Chinese medicine for treating coronary atherosclerotic heart disease caused by qi deficiency and blood stasis |
| CN104127652A (en) * | 2014-07-24 | 2014-11-05 | 孙苗苗 | Medicine for treating coronary heart disease |
| CN104288680A (en) * | 2014-09-29 | 2015-01-21 | 萧开伟 | Liver-protecting and heart-nourishing tablet and preparation method thereof |
| CN105796789A (en) * | 2014-12-14 | 2016-07-27 | 张雪松 | Traditional Chinese medicine preparation for treating coronary heart disease |
| CN105477556A (en) * | 2015-12-30 | 2016-04-13 | 杨桂珍 | Medicine for treating myocardial infarction type coronary heart disease |
| CN105816722A (en) * | 2016-05-10 | 2016-08-03 | 贾敏 | Traditional Chinese medicine preparation for treating coronary artery atherosclerotic heart disease |
| CN105998610A (en) * | 2016-05-30 | 2016-10-12 | 姚新亮 | Traditional Chinese medicinal composition for treating coronary heart disease and preparation method thereof |
| CN108404037A (en) * | 2017-02-09 | 2018-08-17 | 林峰 | A kind of turbid Chinese medicine compositions of promoting blood circulation of the Wen Yanghua treating artery plaque |
| CN108404037B (en) * | 2017-02-09 | 2020-12-29 | 林畅 | Traditional Chinese medicine composition for warming yang, eliminating turbidity and dredging collaterals for treating arterial plaque |
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