CN103444722B - A kind of bactericidal composition containing phenoxyquinoline and triazoles - Google Patents

Abstract

The invention discloses a bactericidal composition containing phenoxyquinoline and triazoles. The bactericidal composition contains active ingredient A and active ingredient B. The active ingredient A is selected from phenoxyquinoline, and the active ingredient B is triazoles. Fungicides, the triazole fungicides are selected from any one of the following compounds: tetrafluconazole, flufenazole, hexaconazole, difenoconazole, fluconazole, epoconazole, and the active ingredient A The weight ratio to active ingredient B is 1:60~80:1. The composition of the invention has relatively high activity on various diseases on various crops, has obvious synergistic effect, and expands the bactericidal spectrum. And it has the characteristics of small dosage, resistance to rain erosion, and obvious synergistic effect. 1-->

Description

A kind of bactericidal composition containing phenoxyquinoline and triazoles

technical field

The invention belongs to the technical field of pesticides, and relates to the application of a fungicidal composition containing phenoxyquinoline and triazoles on crop diseases.

technical background

Phenoxyquin (Quinoxyfen) chemical name: 5,7-dichloro-4-quinolyl-4-fluorophenyl ether, molecular formula: C ₁₅ H ₈ Cl ₂ FNO. Phenoxyquinoline is a systemic fungicide with vapor-phase activity, which facilitates redistribution throughout the plant. Phenoxyquinoline is a growth signal disruptor. Studies have shown that it is neither a sterol biosynthesis inhibitor nor a dihydroorotate dehydrogenase inhibitor. This product is a protective fungicide with good mobility, can inhibit the growth of appressoria, and has no eradicating effect.

Triazole fungicides have broad-spectrum sterilization—high activity against many kinds of pathogenic fungi such as Ascomycetes, Basidiomycetes, and Deuteromycetes, but are inactive against oomycetes; high efficiency—high efficacy and reduced dosage; long-lasting effect Long period - 15-20 days for leaf surface, about 80 days for seed treatment, and 100 days for soil treatment, all of which are longer than ordinary fungicides, and prolong with the increase of dosage; good systemic transport, fast absorption speed, and easy application After 2 hours, the amount of triadimefon absorbed can inhibit the growth of powdery mildew; it has strong preventive and protective effects, good therapeutic effects, fumigation and eradication effects. The mechanism of action is to affect the biosynthesis of sterols and destroy the cell membrane function of bacteria.

In the actual process of agricultural production, the most likely problem in disease control is the emergence of disease resistance. Combination of ingredients from different varieties is a common method for controlling resistant diseases. Different ingredients are compounded, and according to the actual application effect, it is judged whether a certain compound is synergistic, additive or antagonistic. In most cases, the compounding effects of pesticides are additive effects, and there are very few compoundings that really have synergistic effects, especially those with very obvious synergistic effects and high synergistic ratios. After research by the inventors, it was found that compounding phenoxyquinoline with tetrafluconazole, fluconazole, hexaconazole, difenoconazole, trifluconazole, and epoconazole has a good effect within a certain range. Synergistic effect, and there are no related reports about the compounding of phenoxyquinoline with tetrafluconazole, fluconazole, hexaconazole, difenoconazole, trifluconazole, and epoconazole .

Contents of the invention

The object of the present invention is to propose a bactericidal composition containing phenoxyquinoline and triazoles with synergistic effect, low use cost and good control effect.

The present invention is realized through the following technical solutions:

A bactericidal composition containing phenoxyquinoline and triazoles, characterized in that it contains active ingredient A and active ingredient B, the weight ratio of active ingredient A to active ingredient B is 1: 60 ~ 80: 1, the active ingredient Ingredient A is selected from phenoxyquinoline, active ingredient B is a triazole fungicide, and the triazole fungicide is selected from any one of the following compounds: tetrafluconazole, fluconazole, hexaconazole, phenyl ether One of meconazole, fluconazole, econazole; the preferred weight ratio of active ingredient A to active ingredient B is 1:40~60:1; more preferably the weight of phenoxyquinoline and tetraflumeconazole The ratio is 1︰10~30︰1; the weight ratio of phenoxyquinoline to fluconazole or triconazole is 1︰10~20︰1; the weight ratio of phenoxyquinoline to hexaconazole is 1︰10~ 30:1; the weight ratio of phenoxyquinoline to difenoconazole or econazole is 1:30~20:1.

The fungicidal composition containing phenoxyquinoline and triazoles is used to prevent and control crop diseases, and the crops include food crops, bean crops, fiber crops, sugar crops, melon crops, fruit crops, Dried fruit crops, hobby crops, root crops, oil crops, flower crops, medicinal crops, raw material crops, green manure pasture crops.

The diseases include powdery mildew, rust, smut, glume blight, moire, sheath blight, leaf spot, spotted leaf spot, scab, gray mold, leaf blight, early blight, black Pox, spotted blight, black spot, anthracnose, scab.

The content of the active ingredient in the composition of the present invention depends on the application amount when used alone, also depends on the mixing ratio of one compound and another compound and the degree of synergistic effect, and is also related to the target disease. Usually the weight percentage of the active ingredient in the composition is 1%-90% of the total weight, preferably 5%-80%. Depending on the type of preparation, the content range of the active ingredient is different. Usually, liquid preparations contain 1% to 60% by weight of active substances, preferably 5% to 50%; solid preparations contain 5% to 80% by weight of active substances, preferably 10% to 80% %.

The fungicidal composition of the present invention contains at least one surfactant to facilitate the dispersion of active ingredients in water during application. The surfactant content is 2% to 30% of the total weight of the preparation, and the balance is solid or liquid diluent.

The surfactant selected for the bactericidal composition of the present invention is well known to those skilled in the art: it can be selected from one or more of dispersants, wetting agents, thickeners or defoamers. According to different dosage forms, the preparation may also contain stabilizers, antifreezing agents and the like known to those skilled in the art.

The antiseptic composition of the present invention can be diluted or directly used by users before use. Its preparation can be prepared by processing methods known to those skilled in the art, that is, after the active ingredient is mixed with a liquid solvent or a solid carrier, and then added to a surfactant such as a dispersant, a stabilizer, a wetting agent, a binder, an antifoaming agent, etc. one or more of.

The fungicidal composition of the present invention can be processed into any pesticide-acceptable dosage form as required. Among them, the preferred formulations are wettable powder, water dispersible granule, suspension, suspoemulsion, microemulsion, water emulsion, microcapsule suspension, and microcapsule suspension-suspension.

When the composition is made into wettable powder, it contains the following components and contents: active ingredient A 1%~80%, active ingredient B 1%~60%, dispersant 1%~12%, wetting agent 1%~8%, filler margin.

When the composition is made into water-dispersible granules, it includes the following components and contents: active ingredient A 1%~80%, active ingredient B 1%~60%, dispersant 1%~12%, wetting agent 1%~8%, Disintegrant 1%~10%, binder 0~8%, filler balance.

When the composition is made into a suspension, it includes the following components and contents: active ingredient A 1%~50%, active ingredient B 1%~50%, dispersant 1%~10%, wetting agent 1%~10%, defoaming agent 0.01%~2% of agent, 0~2% of thickener, 0~8% of antifreeze, and 100% of deionized water.

When the composition is made into a suspoemulsion, it includes the following components and contents: active ingredient A 1%~50%, active ingredient B 1%~50%, emulsifier 1%~10%, dispersant 1%~10%, solvent 1 %~20%, defoamer 0.01%~2%, thickener 0~2%, antifreeze 0~8%, deionized water to 100%.

When the composition is made into a microemulsion, it includes the following components and contents: active ingredient A1%~50%, active ingredient B1%~50%, emulsifier 3%~25%, solvent 1%~10%, antifreeze agent 0~ 8%, defoamer 0.01%~2%, deionized water to 100%.

When the composition is made into water emulsion, it includes the following components and contents: active ingredient A 1%~50%, active ingredient B 1%~50%, solvent 1%~20%, emulsifier 1%~12%, antifreeze 0~8%, defoamer 0.01%~2%, thickener 0~2%, deionized water to 100%.

Main technical index of wettable powder of the present invention:

Water-dispersible granule main technical index of the present invention:

Suspending agent main technical index of the present invention:

Suspoemulsion main technical index of the present invention:

Microemulsion main technical index of the present invention:

Water-emulsion main technical index of the present invention:

The advantages of the present invention are: (1) The composition of the present invention has a good synergistic and long-lasting effect within a certain range, and the control effect is higher than that of a single dose; (2) The dosage of pesticides is reduced, and the residues of pesticides on crops are reduced (3) The bactericidal spectrum has been expanded to treat a variety of diseases such as powdery mildew, rust, smut, glume blight, moire, sheath blight, leaf spot, leaf spot, scab Botrytis, gray mold, leaf blight, early blight, black pox, spotted blight, black spot, anthracnose, and scab all have high activity.

detailed description

The present invention will be further described below in conjunction with the examples. The percentages in the examples are all percentages by weight, but the present invention is not limited thereto.

Application Example 1

Example 1~20 wettable powder

Mix phenoxyquinoline, active ingredient B, dispersant, wetting agent, and filler, mix uniformly in a mixing tank, pulverize through a jet mill, and then mix uniformly to produce the wettable powder product of the present invention. See Table 1 and 2 for details.

Table 1 Components and content of examples 1 to 10

Table 2 Examples 11~20 each component and content

Example 21~38 water dispersible granules

Phenoxyquinoline, active ingredient B, dispersant, wetting agent, disintegrating agent, and filler are crushed together by airflow to obtain the required particle size, and then other additives such as binder (optional) are added to obtain the preparation grain materials. The water-dispersible granule product of the present invention is obtained by quantitatively sending the material into a fluidized bed granulation dryer for granulation and drying. See Table 3 for details.

Table 3 Examples 21~38 each component and content

Example 39~56 Suspending agent

Dispersant, wetting agent, thickener (can be added or not), defoamer, antifreeze (can be added or not) are mixed evenly through high-speed shearing, then phenoxyquinoline and active ingredient B are added, and deionized Make up the balance with water, and ball mill in a ball mill for 2 to 3 hours, so that the particle size is all below 5 μm, and the suspending agent product of the present invention is obtained. See Table 4 for details.

Table 4 Examples 39~56 each component and content

Example 57 ~ 72 suspoemulsion

Mix dispersant, defoamer, thickener (optional), antifreeze (optional), deionized water through high-speed shearing, add phenoxyquinoline, and mill in a ball mill for 2~ For 3 hours, make the particle size of all the particles below 5 μm to prepare the phenoxyquinoline suspension, and then add tetrafluconazole or fluconazole or hexaconazole or difenoconazole, solvent, emulsifier and various assistants The agent is directly emulsified into the suspending agent with a high-speed stirrer to prepare the suspoemulsion product of the present invention.

Mix dispersant, defoamer, thickener (optional), antifreeze (optional), deionized water through high-speed shearing, add epoconazole or triconazole, and put it in a ball mill Ball mill for 2 to 3 hours, so that the particle size is all below 5 μm, to prepare epoconazole or triconazole suspension concentrate, and then directly emulsify phenoxyquinoline, solvent, emulsifier and various additives with a high-speed mixer to In the suspending agent, the suspoemulsion product of the present invention is obtained. See Tables 5, 6, and 7 for details.

Each component and content of table 5 example 57～62

Each component and content of table 6 example 63～67

Each component and content of table 7 example 68～72

Example 73~87 water emulsion

Add phenoxyquinoline, active ingredient B, solvent, and emulsifier together to dissolve into a uniform oil phase; add deionized water, antifreeze (optional), thickener (optional), The defoamers are mixed together to form a homogeneous aqueous phase. Under high-speed stirring, the water phase is added to the oil phase to prepare the water emulsion product of the present invention. See Table 8 for details.

Each component and content of table 8 example 73～87

New preparations can be obtained by exchanging tetrafluconazole, fluconazole, hexaconazole, difenoconazole, trifluconazole, and epoconazole in Tables 1 to 8.

Example 88 ~ 90 microemulsion

Dissolve phenoxyquinoline and active ingredient B in a homogenizer with solvent, add emulsifier, antifreeze (optional), and defoamer into the homogenizer with the above solution, and use After making up the balance with deionized water, vigorously mix and homogenize to obtain the microemulsion product of the present invention with a clear and transparent appearance. See Table 9 for details.

Table 9 Example 88~90 each component and content

Example 91 ~ 93 microcapsule suspension

Mix phenoxyquinoline, active ingredient B, polymer capsule wall material, and solvent to dissolve into a uniform oil phase. Under shearing conditions, add the oil phase to the In the aqueous phase solution of the agent, make up the balance with deionized water, and the two materials react at the oil-water interface to form a polymer capsule wall to make a well-dispersed microcapsule suspension product of the composition of the present invention. See Table 10 for details.

Table 10 Example 91～93 each component and content

Example 94~96 Microcapsule Suspension-Suspension Concentrate

Mix tetrafluconazole or fluconazole or hexaconazole or difenoconazole, polymer capsule wall material, and solvent to dissolve into a uniform oil phase, and add the oil phase to the mixture containing emulsifier, A well-dispersed microcapsule suspension is prepared in the aqueous phase solution of the pH regulator. Dispersant, wetting agent, defoamer, thickener (can be added or not) are mixed evenly by high-speed shearing, and phenoxyquinoline is added, and ball milled in a ball mill for 2 to 3 hours, so that the particle size of all particles is below 5 μm , to prepare a suspending agent, and then adding the suspending agent to the aqueous phase solution of the microcapsule suspending agent, and supplementing the balance with deionized water, so as to make a well-dispersed microcapsule suspension-suspension agent product of the composition of the present invention.

Mix phenoxyquinoline, polymer capsule wall material, and solvent to dissolve into a uniform oil phase, and add the oil phase to the aqueous phase solution containing emulsifier and pH regulator under shearing conditions to make a well-dispersed microcapsule suspension. Dispersant, wetting agent, defoamer, thickener (may or may not be added) are mixed evenly by high-speed shearing, add triconazole or epoxiconazole, and ball mill in a ball mill for 2 to 3 hours to make the particle size completely Below 5 μm, prepare a suspending agent, then add the suspending agent to the aqueous phase solution of the microcapsule suspending agent, make up the balance with deionized water, and make a well-dispersed microcapsule suspension-suspension agent product of the composition of the present invention. See Table 11 for details.

Table 11 Example 94～96 each component and content

The embodiment of the present invention adopts the method combining indoor virulence determination and field test. Firstly, through the indoor toxicity test, the synergistic ratio (SR) of the two agents after compounding in a certain proportion is clarified. SR<0.5 is an antagonistic effect, 0.5≤SR≤1.5 is an additive effect, and SR>1.5 is a synergistic effect. On this basis, field experiments were carried out.

Test method: After pre-testing to determine the effective inhibitory concentration range of each drug, 5 doses of drugs were set according to the content of active ingredients, and water was used as a control. Refer to the "Pesticide Indoor Bioassay Test Guidelines for Fungicides", and use the mycelium growth rate method to determine the toxicity of the pesticides to crop pathogens. After 72 hours, the colony diameter was measured by the cross method, and the net growth and mycelial growth inhibition rate of each treatment were calculated.

Net growth (mm) = measured colony diameter -5

The mycelial growth inhibition rate was converted into a probability value (y), the concentration of the drug solution (μg/mL) was converted into a logarithmic value (x), and the toxicity regression equation (y=a+bx) was obtained by the least square method, and the This calculates the _EC50 value for each agent. At the same time, according to the Wadley method, the synergistic ratio (SR) of the combination of different proportions of the two agents was calculated. SR<0.5 was considered antagonism, 0.5≤SR≤1.5 was additive, and SR>1.5 was synergistic. Calculated as follows:

Wherein: a, b are respectively the ratio of active ingredient A and active ingredient B in the combination;

A is phenoxyquinoline; B is selected from one of tetrafluconazole, fluconazole, hexaconazole, difenoconazole, trifluconazole and econazole.

Application example two:

Tested disease: grape powdery mildew; test agents were provided by Shaanxi Welch Crop Protection Co., Ltd.; test design: through preliminary tests to determine the effectiveness of phenoxyquinoline and Tetrafluconazole original drug and the mixture of the two different ratios Inhibitory concentration range.

Toxicity test results

Table 12 Analysis table of toxicity test results of phenoxyquinoline and tetrafluconazole compound against grape powdery mildew

It can be seen from Table 12 that when the compounding ratio of phenoxyquinoline and tetrafluranazole for the prevention and treatment of grape powdery mildew is 1:60~80:1, the synergistic ratio SR is greater than 1.5, indicating that the ratio of the two is greater than 1:60~80. The synergistic effect was shown in the mixture within the range of ︰1, and the synergistic effect was more prominent when the ratio of phenoxyquinoline and tetrafluconazole was in the range of 1︰10~30︰1, and the synergistic ratios were all greater than 2.30. After testing, it was found that the optimal ratio of phenoxyquinoline to tetraflumezole was 30:1, 25:1, 20:1, 15:1, 10:1, 9:1, 8:1, 7:1, 6:1, 5:1, 4:1, 3:1, 2:1, 1:1, 1:2, 1:3, 1:4, 1:5, 1:10, especially when phenoxyquin The synergistic ratio is the largest and the synergistic effect is the most obvious when the weight ratio of morphine and tetraflumezole is 3:1.

Application Example Three:

The disease to be tested: pear tree scab; the test agents were provided by Shaanxi Welch Crop Protection Co., Ltd.; the design of the test: through the preliminary test, the effects of phenoxyquinoline and flucloconazole as the original drug and the mixture of the two in different ratios were determined. Effective inhibitory concentration range.

Toxicity test results

Table 13 Analysis of the toxicity test results of pear tree scab compounded with phenoxyquinoline and flufenazole

It can be seen from Table 13 that when the compounding ratio of phenoxyquinoline and flufenazole for the prevention and treatment of pear scab is 1:60~80:1, the synergistic ratio SR is greater than 1.5, indicating that the ratio of the two is greater than 1:60~ The compounding within the range of 80︰1 showed synergistic effect, and when the ratio of phenoxyquinoline and flubuconazole was 1︰10~20︰1, the synergistic effect was more prominent, and the synergistic ratio was greater than 2.30. After testing, it is found that the optimal ratio of phenoxyquinoline to flufenazole is 20:1, 15:1, 10:1, 9:1, 8:1, 7:1, 6:1, 5:1, 4 :1, 3:1, 2:1, 1:1, 1:2, 1:3, 1:4, 1:5, 1:6, 1:7, 1:8, 1:9, 1:10 , especially when the weight ratio of phenoxyquinoline and flufenazole is 2:1, the synergistic ratio is the largest, and the synergistic effect is the most obvious.

Application example four:

Tested disease: rice sheath blight; test agents are provided by Shaanxi Welch Crop Protection Co., Ltd.; test design: through preliminary tests to determine the effectiveness of phenoxyquinoline and hexaconazole original drug and the mixture of the two different ratios Inhibitory concentration range.

Toxicity test results

Table 14 Analysis of the toxicity test results of the combination of phenoxyquinoline and hexaconazole against rice sheath blight

It can be seen from Table 14 that when the combination ratio of phenoxyquinoline and hexaconazole for the control of rice sheath blight is 1:60~80:1, the synergistic ratio SR is greater than 1.5, indicating that the ratio of the two is greater than 1:60~80. The synergistic effects were all shown in the range of ︰1. When the ratio of phenoxyquinoline and hexaconazole was 1︰10~30︰1, the synergistic effect was more prominent, and the synergistic ratios were all greater than 2.15. It is found through experiments that the optimal ratio of phenoxyquinoline to hexaconazole is 30:1, 25:1, 20:1, 15:1, 14:1, 13:1, 12:1, 11:1, 10 :1, 9:1, 8:1, 7:1, 6:1, 5:1, 1:1, 1:2, 1:3, 1:4, 1:5, 1:10, especially when When the weight ratio of phenoxyquinoline and hexaconazole was 6:1, the synergistic ratio was the largest, and the synergistic effect was the most obvious.

Application embodiment five:

The disease to be tested: watermelon anthracnose; the test agents were provided by Shaanxi Welch Crop Protection Co., Ltd.; the design of the test: through a preliminary test, the effects of phenoxyquinoline and difenoconazole as the original drug and the mixture of the two in different ratios were determined. Effective inhibitory concentration range.

Toxicity test results

Table 15 Analysis of the toxicity test results of the combination of phenoxyquinoline and difenoconazole against watermelon anthracnose

It can be seen from Table 15 that when the combination ratio of phenoxyquinoline and difenoconazole for the prevention and treatment of watermelon anthracnose is 1:60~80:1, the synergistic ratio SR is greater than 1.5, indicating that the ratio of the two is greater than 1:60~ 80︰1 range of mixing all showed synergistic effect, when the ratio of phenoxyquinoline and difenoconazole was 1︰30~20︰1, the synergistic effect was more prominent, and the synergistic ratios were greater than 2.20. After testing, it is found that the optimal ratio of phenoxyquinoline to difenoconazole is 20:1, 15:1, 10:1, 9:1, 8:1, 7:1, 6:1, 5:1 , 4:1, 3:1, 2:1, 1:1, 2:3, 1:2, 1:3, 1:4, 1:5, 1:6, 1:7, 1:8, 1 :9, 1:10, 1:15, 1:20, 1:25, 1:30, especially when the weight ratio of phenoxyquinoline and difenoconazole is 2:3, the synergistic ratio is the largest, and the synergistic The most obvious effect.

Application example six:

The disease tested: wheat powdery mildew; the test agents were provided by Shaanxi Welch Crop Protection Co., Ltd.; the test design: the effective inhibition of phenoxyquinoline and triadol and the mixture of the two in different proportions were determined through preliminary tests concentration range.

Toxicity test results

Table 16 Analysis table of the toxicity test results of the combination of phenoxyquinoline and flutriazole against wheat powdery mildew

It can be seen from Table 16 that when the compounding ratio of phenoxyquinoline and flutriazole to control wheat powdery mildew is 1:60~80:1, the synergistic ratio SR is greater than 1.5, indicating that the two are at 1:60~80: The synergistic effects were all shown in the range of 1. When the ratio of phenoxyquinoline and triconazole was 1:10~20:1, the synergistic effect was more prominent, and the synergistic ratios were all greater than 2.30. It is found through experiments that the optimal ratio of phenoxyquinoline to triazol is 20:1, 15:1, 10:1, 9:1, 8:1, 7:1, 6:1, 5:1, 4 :1, 3:1, 2:1, 1:1, 2:3, 1:2, 1:3, 1:4, 1:5, 1:6, 1:7, 1:8, 1:9 , 1:10, especially when the weight ratio of phenoxyquinoline and triazol is 2:1, the synergistic ratio is the largest, and the synergistic effect is the most obvious.

Application embodiment seven:

The disease to be tested: banana leaf spot; the test agents were provided by Shaanxi Welch Crop Protection Co., Ltd.; the test design: through the preliminary test to determine the effectiveness of the original drug of phenoxyquinoline and epoxiconazole and the mixture of the two in different proportions. Inhibitory concentration range.

Toxicity test results

Table 17 Analysis of the toxicity test results of phenoxyquinoline and epoxiconazole compound against banana leaf spot

It can be seen from Table 17 that when the combination ratio of phenoxyquinoline and epoxiconazole for the control of banana leaf spot is 1:60~80:1, the synergistic ratio SR is greater than 1.5, indicating that the ratio of the two is 1:60~80 The synergistic effects were all shown in the range of ︰1. When the ratio of phenoxyquinoline and epoxiconazole was 1︰30~20︰1, the synergistic effect was more prominent, and the synergistic ratios were all greater than 2.30. After testing, it is found that the optimal ratio of phenoxyquinoline to epoxiconazole is 20:1, 15:1, 10:1, 9:1, 8:1, 7:1, 6:1, 5:1, 4 :1, 3:1, 2:1, 1:1, 2:3, 1:2, 1:3, 1:4, 1:5, 1:6, 1:7, 1:8, 1:9 , 1:10, 1:15, 1:20, 1:25, 1:30, especially when the weight ratio of phenoxyquinoline and epoxiconazole is 2:3, the synergistic ratio is the largest and the synergistic effect is most obvious.

It has been found through tests that the compounding of phenoxyquinoline and active ingredient B is effective against powdery mildew, rust, smut, glume blight, moire, sheath blight, leaf spot, spotted leaf spot, scab, ash Mildew, leaf blight, early blight, black pox, spotted blight, black spot, anthracnose, and scab have obvious synergistic effects, and the synergistic ratios are all above 1.50.

Drug efficacy test part

All test agents were developed and provided by Shaanxi Welch Crop Protection Co., Ltd. Control drug: 20% phenoxyquinoline emulsifiable concentrate (self-prepared), 4% tetrafluconazole aqueous emulsion (commercially available), 30% flufenazole wettable powder (commercially available), 5% hexaconazole suspension (commercially available) purchased), 10% difenoconazole aqueous emulsion (commercially available), 12.5% triadol suspension (self-prepared), 12.5% epoconazole suspension (commercially available).

Application Example 8 Phenoxyquinoline and Active Ingredient B and Their Compound Control Efficacy Test on Grape Powdery Mildew

The experiment was arranged in the suburbs of Weinan City, Shaanxi Province, and the condition of grape powdery mildew was investigated before the drug application. The drug was applied for the first time in the early stage of the disease, and the drug was applied every 7 days, and the drug was applied twice in total. 10 days, 30 days, and 45 days after the last application, the disease index was investigated and the control effect was calculated. The experimental results are as follows:

Table 18 Efficacy test of phenoxyquinoline and active ingredient B and its compound in controlling grape powdery mildew

It can be seen from Table 18 that the combination of phenoxyquinoline and active ingredient B can effectively control grape powdery mildew, and the control effect is better than that of a single agent, and the control effect period is long. There is no adverse effect on the target crops within the scope of the test drug.

Application Example 9 Phenoxyquinoline and Active Ingredient B and Their Compound Control Efficacy Test of Apple Spotted Leaf Blight

This experiment was arranged in Xianyang City, Shaanxi Province. The disease of apple spotted leaf defoliation was investigated before the drug application. The drug was applied for the first time in the early stage of the disease, and the drug was applied every 7 days, and the drug was applied twice. 10 days, 30 days, and 45 days after the last application, the disease index was investigated and the control effect was calculated. The experimental results are as follows:

Table 19 Efficacy test of phenoxyquinoline and active ingredient B and its compound in the control of apple spotted leaf disease

It can be seen from Table 19 that the combination of phenoxyquinoline and active ingredient B can effectively prevent and control apple leaf spot disease, and the control effect is better than that of a single agent, and the control effect period is long. There is no adverse effect on the target crops within the scope of the test drug.

Application Example 10 Phenoxyquinoline and Active Ingredient B and Their Compound Drug Efficacy Test for Prevention and Treatment of Pear Tree Scab

This experiment was arranged in Xianyang City, Shaanxi Province, and the condition of pear scab was investigated before the drug application. The drug was applied for the first time in the early stage of the disease, and the drug was applied every 7 days, and the drug was applied twice. 10 days, 30 days, and 45 days after the last application, the disease index was investigated and the control effect was calculated. The experimental results are as follows:

Table 20 Efficacy test of phenoxyquinoline and active ingredient B and its compound in the control of pear scab

It can be seen from Table 20 that the combination of phenoxyquinoline and active ingredient B can effectively control pear scab, and the control effect is better than that of a single agent, and the control effect period is long. There is no adverse effect on the target crops within the scope of the test drug.

Application Example 11 Phenoxyquinoline and Active Ingredient B and their Compound Efficacy Test for Controlling Banana Leaf Spot

The experiment was conducted in Nanning, Guangxi, and the condition of banana leaf spot was investigated before the drug application. The drug was applied for the first time at the early stage of the disease, and the drug was applied every 7 days, and the drug was applied twice in total. 10 days, 30 days, and 45 days after the last application, the disease index was investigated and the control effect was calculated. The experimental results are as follows:

Table 21 Efficacy test of phenoxyquinoline and active ingredient B and its compound in the control of banana leaf spot

It can be seen from Table 21 that the combination of phenoxyquinoline and active ingredient B can effectively control banana leaf spot, and the control effect is better than that of a single agent, and the control effect period is long. There is no adverse effect on the target crops within the scope of the test drug.

Application Example 12 Phenoxyquinoline and active ingredient B and its compound efficacy test for controlling rice sheath blight

This experiment was arranged in Hanzhong City, Shaanxi Province, and the disease of rice sheath blight was investigated before the drug application. The drug was applied for the first time in the early stage of the disease, and the drug was applied every 7 days, and the drug was applied twice in total. 10 days, 30 days, and 45 days after the last application, the disease index was investigated and the control effect was calculated. The experimental results are as follows:

Table 22 Efficacy test of phenoxyquinoline and active ingredient B and its compound in controlling rice sheath blight

It can be seen from Table 22 that the combination of phenoxyquinoline and active ingredient B can effectively control rice sheath blight, and the control effect is better than that of a single agent, and the control effect period is long. There is no adverse effect on the target crops within the scope of the test drug.

Application example thirteen Phenoxyquinoline and active ingredient B and its compound efficacy test for controlling cucumber powdery mildew

This experiment was arranged in Jingyang County, Shaanxi Province. The condition of cucumber powdery mildew was investigated before the drug application. The drug was applied for the first time at the early stage of the disease, and the drug was applied every 7 days, and the drug was applied twice in total. 10 days, 30 days, and 45 days after the last application, the disease index was investigated and the control effect was calculated. The experimental results are as follows:

Table 23 Efficacy test of phenoxyquinoline and active ingredient B and its compound in controlling cucumber powdery mildew

It can be seen from Table 23 that the combination of phenoxyquinoline and active ingredient B can effectively control cucumber powdery mildew, and the control effect is better than that of a single agent, and the control effect period is long. There is no adverse effect on the target crops within the scope of the test drug.

Application Example 14: Phenoxyquinoline and Active Ingredient B and Their Compound Efficacy Test for Controlling Watermelon Anthracnose

This experiment was arranged in Dali County, Weinan City, Shaanxi Province. The condition of watermelon anthracnose was investigated before the drug treatment. The drug was applied for the first time at the early stage of the disease, and the drug was applied every 7 days, and the drug was applied twice in total. 10 days, 30 days, and 45 days after the last application, the disease index was investigated and the control effect was calculated. The experimental results are as follows:

Table 24 Efficacy test of phenoxyquinoline and active ingredient B and its compound in controlling watermelon anthracnose

It can be seen from Table 24 that the combination of phenoxyquinoline and active ingredient B can effectively control watermelon anthracnose, and the control effect is better than that of a single agent, and the control effect period is long. There is no adverse effect on the target crops within the scope of the test drug.

Application Example 15 Phenoxyquinoline and Active Ingredient B and Their Compound Control Efficacy Test on Wheat Rust

This experiment was arranged in Weinan City, Shaanxi Province. The condition of wheat rust was investigated before the treatment. The pesticide was applied for the first time in the early stage of the disease, and the pesticide was applied every 7 days, and the pesticide was applied twice in total. 10 days, 30 days, and 45 days after the last application, the disease index was investigated and the control effect was calculated. The experimental results are as follows:

Table 25 Efficacy test of phenoxyquinoline and active ingredient B and its compound in the control of wheat rust

It can be seen from Table 25 that the combination of phenoxyquinoline and active ingredient B can effectively control wheat rust, and the control effect is better than that of a single agent, and the control effect period is long. There is no adverse effect on the target crops within the scope of the test drug.

Application Example 16 Phenoxyquinoline and Active Ingredient B and Their Compound Control Efficacy Test on Flower Powdery Mildew

This experiment was arranged in Weinan City, Shaanxi Province. The disease of flower powdery mildew was investigated before the drug application. The drug was applied for the first time in the early stage of the disease, and the drug was applied every 7 days, and the drug was applied twice. 10 days, 30 days, and 45 days after the last application, the disease index was investigated and the control effect was calculated. The experimental results are as follows:

Table 26 Efficacy test of phenoxyquinoline and active ingredient B and its compound in controlling flower powdery mildew

It can be seen from Table 26 that the combination of phenoxyquinoline and active ingredient B can effectively control powdery mildew of flowers, and the control effect is better than that of a single agent, and the control effect period is long. There is no adverse effect on the target crops within the scope of the test drug.

Afterwards, through tests in different places across the country, it was concluded that the compounding of phenoxyquinoline with tetrafluconazole, flufenazole, hexaconazole, difenoconazole, trifluconazole, and epoconazole has the effect on various crops. Powdery mildew, rust, smut, glume blight, moire, sheath blight, leaf spot, leaf spot, scab, gray mold, leaf blight, early blight, black pox, Spot blight, black spot, anthracnose, scab and other common diseases have a control effect of more than 95%, which is better than a single agent control effect, and the synergistic effect is obvious.

Claims (6)

1. A bactericidal composition containing phenoxyquinoline and triazoles, characterized in that effective active ingredients are active ingredient A and active ingredient B, and the weight ratio of active ingredient A to active ingredient B is 1: 60 ~ 80: 1 , the active ingredient A is phenoxyquinoline, and the active ingredient B is flufenazole. 2. The bactericidal composition containing phenoxyquinoline and triazoles according to claim 1, wherein the weight ratio of active ingredient A to active ingredient B is 1:40~60:1. 3. The fungicidal composition containing phenoxyquinoline and triazoles according to claim 2, characterized in that: the weight ratio of phenoxyquinoline to flufenazole is 1:10~20:1. 4. The fungicidal composition containing phenoxyquinoline and triazoles according to any one of claims 1 to 3, characterized in that: the composition is made into wettable powder, water dispersible granule, suspending agent, suspension Emulsion, microemulsion, aqueous emulsion, microcapsule suspension, microcapsule suspension-suspension concentrate. 5. the application of the fungicidal composition containing phenoxyquinoline and triazoles according to claim 4 for the prevention and treatment of crop diseases. 6. The application according to claim 5, characterized in that: the diseases are powdery mildew, rust, smut, glume blight, moire, sheath blight, leaf spot, leaf spot, black Star disease, gray mold, leaf blight, early blight, black pox, spotted blight, black spot, anthracnose, scab.