CN103356962B - Traditional Chinese medicine composition for treating climacteric syndrome - Google Patents
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Abstract
The invention relates to a traditional Chinese medicine composition for treating climacteric syndrome. The traditional Chinese medicine composition comprises the following traditional Chinese medicine raw materials: by weight, 5-20 parts of tree peony bark, 5-25 parts of cape jasmine, 5-25 parts of radix bupleuri, 10-30 parts of Chinese angelica, 10-40 parts of bighead atractylodes rhizome, 10-40 parts of white peony root, 10-30 parts of poria, 5-20 parts of balloonflower root, 5-20 parts of banksia rose, 5-25 parts of green tangerine peel, 5-25 parts of dried orange peel, 5-20 parts of pinellia ternate, 5-20 parts of radish seed, 5-20 parts of villous amomum fruit, 5-25 parts of holboellia latifolia, 5-20 parts of bitter orange, 5-20 parts of morinda officinalis, 10-40 parts of epimeddium, 5-25 parts of radix curcumae, 5-20 parts of cyperus rotundus, 5-20 parts of mint, 5-20 parts of vegetable sponge of luffa, 5-20 parts of puncturervine caltrop fruit, 10-30 parts of ligusticum wallichii, 10-30 parts of rhizoma corydalis and 5-15 parts of licorice. The traditional Chinese medicine composition has the efficacy of smoothing liver and regulating vital energy, strengthening spleen and tonifying kidney, nourishing blood and promoting blood circulation, and clearing heart and dispelling melancholy, and has a significant curative effect and a reliable effect on treatment of the climacteric syndrome.
Description
Technical field
The present invention relates to a kind of pharmaceutical product not determining structure of traditional herbal medicines, especially a kind of Chinese medicine composition for the treatment of climacteric syndrome.
Background technology
Climacteric syndrome, the traditional Chinese medical science is referred to as " menopausal syndrome ", refers to a series of body before and after postmenopausal women caused by estrogen decrease and psychic symptoms.Its clinical manifestation is: hectic fever, cardiopalmus, spirit and nervous symptoms are abnormal, sore waist and aching in the waist and the back.In recent years because society, life, operating pressure increase, climacteric women symptom is obvious, bears heavy stress, has a strong impact on family life harmony.Most of women can reach new balance and no conscious sympton by neuroendocrine self regulation, also has some women symptom obvious, needs Drug therapy to carry out relief of symptoms.At present, doctor trained in Western medicine many employings complementing estrogen is treated, and as nilestriol, livial etc., but administration time is longer, unsatisfactory curative effect, and there is certain side effect.
The traditional Chinese medical science is thought, climacteric syndrome is many because of deficiency of kidney-QI, and menses declines few, so that imbalance between YIN and YANG causes.Therefore control suitable the kidney invigorating and essence nourishing, benefiting QI for activating blood circulation.
According to theory of Chinese medical science, for the pathogeny of climacteric syndrome, carry out dialectical composition of prescription, to reach the object for the treatment of both the principal and secondary aspects of a disease.
Summary of the invention
There is curative effect and pay no attention to overcome estrin treatment climacteric syndrome in prior art and think of the large deficiency of side effect, the invention provides a kind of prepare easy, cost is low, evident in efficacy, the Chinese medicine composition for the treatment of climacteric syndrome that has no side effect.
The technical solution adopted for the present invention to solve the technical problems is: a kind of Chinese medicine composition for the treatment of climacteric syndrome, it is characterized in that: its raw material of Chinese medicine and weight are: Cortex Moutan 5-20 part, Fructus Gardeniae 5-25 part, Radix Bupleuri 5-25 part, Radix Angelicae Sinensis 10-30 part, Rhizoma Atractylodis Macrocephalae 10-40 part, Radix Paeoniae Alba 10-40 part, Poria 10-30 part, Radix Platycodonis 5-20 part, Radix Aucklandiae 5-20 part, Pericarpium Citri Reticulatae Viride 5-25 part, Pericarpium Citri Reticulatae 5-25 part, Rhizoma Pinelliae 5-20 part, Semen Raphani 5-20 part, Fructus Amomi 5-20 part, Fructus Akebiae 5-25 part, Fructus Aurantii Immaturus 5-20 part, Radix Morindae Officinalis 5-20 part, Herba Epimedii 10-40 part, Radix Curcumae 5-25 part, Rhizoma Cyperi 5-20 part, Herba Menthae 5-20 part, Retinervus Luffae Fructus 5-20 part, Fructus Tribuli 5-20 part, Rhizoma Chuanxiong 10-30 part, Rhizoma Corydalis 10-30 part, Radix Glycyrrhizae 5-15 part.
The preferred technical solution of the present invention is: a kind of Chinese medicine composition for the treatment of climacteric syndrome, it is characterized in that: its raw material of Chinese medicine and weight are: Cortex Moutan 12 parts, Fructus Gardeniae 15 parts, Radix Bupleuri 15 parts, Radix Angelicae Sinensis 20 parts, the Rhizoma Atractylodis Macrocephalae 30 parts, the Radix Paeoniae Alba 30 parts, Poria 20 parts, Radix Platycodonis 10 parts, the Radix Aucklandiae 10 parts, 15 parts, Pericarpium Citri Reticulatae Viride, Pericarpium Citri Reticulatae 15 parts, the Rhizoma Pinelliae 10 parts, Semen Raphani 10 parts, Fructus Amomi 10 parts, Fructus Akebiae 15 parts, Fructus Aurantii Immaturus 10 parts, Radix Morindae Officinalis 10 parts, Herba Epimedii 30 parts, Radix Curcumae 15 parts, Rhizoma Cyperi 10 parts, Herba Menthae 10 parts, Retinervus Luffae Fructus 10 parts, Fructus Tribuli 10 parts, Rhizoma Chuanxiong 20 parts, Rhizoma Corydalis 20 parts, 6 parts, Radix Glycyrrhizae.
Chinese medicine composition of the present invention is under Traditional Chinese medical theory and clinical experience instruct, selected medicament composing prescription.In Chinese medicine composition of the present invention: Cortex Moutan has effect of clearing away heat and cooling blood, promoting blood circulation to remove blood stasis; Fructus Gardeniae has effect of pathogenic fire purging relieving restlessness, clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body; Radix Bupleuri have evacuate bring down a fever, effect of yang invigorating soothing liver-QI; Radix Angelicae Sinensis have enrich blood invigorate blood circulation, menstruction regulating and pain relieving, effect of loosening bowel to relieve constipation; The Rhizoma Atractylodis Macrocephalae has the antiabortive effect of invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis; The Radix Paeoniae Alba has effect of clear and coherent blood vessels, nourishing blood to suppress the hyperactive liver, slow middle arresting sweating; Poria has benefiting vital QI for tranquillizing, invigorating the spleen and regulating the stomach, dispels effect that is damp and hot, row water stopping leak; Radix Platycodonis has lung qi dispersing and eliminates the phlegm, fosters the spirit of nobility and enrich blood, sharp the five internal organs, mend effect of five kinds of over strain; The Radix Aucklandiae has effect of intestinal stasis relieving in promoting the circulation of QI to relieve pain, tune; Pericarpium Citri Reticulatae Viride has the stagnant effect of soothing the liver dispelling the stagnated QI, removing food stagnancyization; Pericarpium Citri Reticulatae has effect of diuretic, drying dampness to eliminate phlegm in regulating qi-flowing for strengthening spleen, tune; The Rhizoma Pinelliae has drying dampness to eliminate phlegm, effect of stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass; Semen Raphani has effect of the de-swelling that helps digestion, lowering the adverse-rising QI to resolve phlegm; Fructus Amomi has removing dampness appetizing, warming spleen and stopping diarrha, antiabortive effect of regulating the flow of vital energy; Fructus Akebiae has effect of liver-smoothing, qi-regulating, promoting blood circulation and stopping pain, relieving restlessness diuresis; Fructus Aurantii Immaturus has effect of loose painful abdominal mass of reducing phlegm, dispelling the stagnated QI removing food stagnancy; Radix Morindae Officinalis has effect of reinforcing the kidney and supporting YANG, bone and muscle strengthening, expelling wind and removing dampness; Herba Epimedii has effect of kidney-replenishing, bone and muscle strengthening, wind-damp dispelling; Radix Curcumae has effect of regulating qi to disperse stagnation, heart fire-clearing upset-relieving; Rhizoma Cyperi has effect of resolving depression of regulating the flow of vital energy, menstruction regulating and pain relieving; Herba Menthae has effect of dispelling wind and heat pathogens, clear profit removing toxic substances, dispersing the stagnated live-QI to relieve the stagnation of QI; Retinervus Luffae Fructus has dredge the meridian passage, heat-clearing and toxic substances removing, inducing diuresis to remove edema, effect of hemostasis; Fructus Tribuli has suppressing the hyperactive liver resolving depression, promoting blood circulation by removing wind, improving eyesight, antipruritic effect; Rhizoma Chuanxiong has effect of blood circulation promoting and blood stasis dispelling, activating QI to alleviate the depression, wind-expelling pain-stopping; Rhizoma Corydalis has effect of promoting blood circulation to remove blood stasis, promoting the circulation of QI pain relieving; Radix Glycyrrhizae has effect of invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, coordinating the actions of various ingredients in a prescription.The selected medicament composing prescription of the present invention, its drug component is through dialectical compatibility, and help using mutually assistant, effect of long memorial liver and qi, strengthening spleen, tonifying kidney, nourshing blood and promoting blood circulation, heart fire-clearing upset-relieving, reaches treating both the principal and secondary aspects of a disease to the treatment of climacteric syndrome altogether.
The component of the present composition all adopts natural raw material of Chinese medicine, and its preparation is easy, medicine source is wide, cost is low.The present invention follows the prescriptions principle of the traditional Chinese medical science, and various component drug adopts the use that is decocted in water for oral dose.Through clinical practice checking, it is reliably evident in efficacy, mild in medicine property and, do not occur toxic and side effects, total effective rate reaches 92.5%, cure rate 68.8%.
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described.
Embodiment 1
Treat a Chinese medicine composition for climacteric syndrome, its raw material of Chinese medicine and weight proportion are: under after Cortex Moutan 12g, Fructus Gardeniae 15g, Radix Bupleuri 15g, Radix Angelicae Sinensis 20g, Rhizoma Atractylodis Macrocephalae 30g, Radix Paeoniae Alba 30g, Poria 20g, Radix Platycodonis 10g, Radix Aucklandiae 10g, Pericarpium Citri Reticulatae Viride 15g, Pericarpium Citri Reticulatae 15g, Rhizoma Pinelliae 10g, Semen Raphani 10g, Fructus Amomi 10g, Fructus Akebiae 15g, Fructus Aurantii Immaturus 10g, Radix Morindae Officinalis 10g, Herba Epimedii 30g, Radix Curcumae 15g, Rhizoma Cyperi 10g, Herba Menthae 10g(), Retinervus Luffae Fructus 10g, Fructus Tribuli 10g, Rhizoma Chuanxiong 20g, Rhizoma Corydalis 20g, Radix Glycyrrhizae 6g.
Embodiment 2
Treat a Chinese medicine composition for climacteric syndrome, its raw material of Chinese medicine and weight proportion are: under after Cortex Moutan 5g, Fructus Gardeniae 25g, Radix Bupleuri 20g, Radix Angelicae Sinensis 10g, Rhizoma Atractylodis Macrocephalae 35g, Radix Paeoniae Alba 10g, Poria 30g, Radix Platycodonis 5g, Radix Aucklandiae 20g, Pericarpium Citri Reticulatae Viride 10g, Pericarpium Citri Reticulatae 5g, Rhizoma Pinelliae 20g, Semen Raphani 15g, Fructus Amomi 20g, Fructus Akebiae 25g, Fructus Aurantii Immaturus 5g, Radix Morindae Officinalis 20g, Herba Epimedii 40g, Radix Curcumae 5g, Rhizoma Cyperi 20g, Herba Menthae 15g(), Retinervus Luffae Fructus 5g, Fructus Tribuli 20g, Rhizoma Chuanxiong 10g, Rhizoma Corydalis 30g, Radix Glycyrrhizae 15g.
Embodiment 3
Treat a Chinese medicine composition for climacteric syndrome, its raw material of Chinese medicine and weight proportion are: under after Cortex Moutan 15g, Fructus Gardeniae 5g, Radix Bupleuri 25g, Radix Angelicae Sinensis 15g, Rhizoma Atractylodis Macrocephalae 40g, Radix Paeoniae Alba 25g, Poria 25g, Radix Platycodonis 15g, Radix Aucklandiae 12g, Pericarpium Citri Reticulatae Viride 20g, Pericarpium Citri Reticulatae 10g, Rhizoma Pinelliae 5g, Semen Raphani 20g, Fructus Amomi 15g, Fructus Akebiae 10g, Fructus Aurantii Immaturus 12g, Radix Morindae Officinalis 5g, Herba Epimedii 25g, Radix Curcumae 20g, Rhizoma Cyperi 15g, Herba Menthae 20g(), Retinervus Luffae Fructus 12g, Fructus Tribuli 5g, Rhizoma Chuanxiong 30g, Rhizoma Corydalis 10g, Radix Glycyrrhizae 5g.
Embodiment 4
Treat a Chinese medicine composition for climacteric syndrome, its raw material of Chinese medicine and weight proportion are: under after Cortex Moutan 20g, Fructus Gardeniae 10g, Radix Bupleuri 5g, Radix Angelicae Sinensis 30g, Rhizoma Atractylodis Macrocephalae 25g, Radix Paeoniae Alba 30g, Poria 10g, Radix Platycodonis 20g, Radix Aucklandiae 15g, Pericarpium Citri Reticulatae Viride 5g, Pericarpium Citri Reticulatae 25g, Rhizoma Pinelliae 12g, Semen Raphani 5g, Fructus Amomi 12g, Fructus Akebiae 5g, Fructus Aurantii Immaturus 20g, Radix Morindae Officinalis 15g, Herba Epimedii 30g, Radix Curcumae 10g, Rhizoma Cyperi 5g, Herba Menthae 12g(), Retinervus Luffae Fructus 20g, Fructus Tribuli 15g, Rhizoma Chuanxiong 25g, Rhizoma Corydalis 15g, Radix Glycyrrhizae 10g.
Embodiment 5
Treat a Chinese medicine composition for climacteric syndrome, its raw material of Chinese medicine and weight proportion are: under after Cortex Moutan 10g, Fructus Gardeniae 20g, Radix Bupleuri 10g, Radix Angelicae Sinensis 25g, Rhizoma Atractylodis Macrocephalae 10g, Radix Paeoniae Alba 40g, Poria 15g, Radix Platycodonis 12g, Radix Aucklandiae 5g, Pericarpium Citri Reticulatae Viride 25g, Pericarpium Citri Reticulatae 20g, Rhizoma Pinelliae 15g, Semen Raphani 12g, Fructus Amomi 5g, Fructus Akebiae 20g, Fructus Aurantii Immaturus 15g, Radix Morindae Officinalis 12g, Herba Epimedii 10g, Radix Curcumae 25g, Rhizoma Cyperi 12g, Herba Menthae 5g(), Retinervus Luffae Fructus 15g, Fructus Tribuli 12g, Rhizoma Chuanxiong 15g, Rhizoma Corydalis 25g, Radix Glycyrrhizae 12g.
Chinese medicine composition in embodiment of the present invention decocting method routinely produces medicament.Concrete grammar is as follows: the raw material of Chinese medicine of prescription is put into container, adds cold water and covers powder, soaks 15 ~ 20 minutes, then adds water and do not have powder about 8 centimetres, carries out first time to decoct, and adopts intense fire to decoct, with slow fire boiling 20 ~ 30 minutes after boiling at a simmer; Second time decocts, and adds water and does not have powder about 6 centimetres, decocts 15 ~ 20 minutes after water boils.Decoct extracting juice twice, merge.
The present invention, with a kind of Chinese medicine composition for the treatment of climacteric syndrome given by embodiment 1, does clinical efficacy and is summarized as follows:
One, general data: this Chinese medicine composition is applied to clinical observation 80 cases, 45 ~ 65 years old age.
Two, diagnosis basis: the diagnostic criteria with reference to climacteric syndrome in People's Republic of China's traditional Chinese medicine industry standard " Chinese medical disease Standardization of diagnosis and curative effect ":
1, mostly occur more than 45 years old, irregular menses or amenorrhea, hectic fever, perspiration, cardiopalmus, emotional, insomnia or the symptom such as depressed;
2, genitals and secondary sex characteristics have atrophy in various degree;
3, urine, blood estrogen reduce, and follicle stimulating hormone and lutropin obviously raise.
Three, usage and dosage: during clinical practice, potion on the one, decocting twice extracting juice is about 300ml, and point morning, evening take for twice.It within five days, is a course for the treatment of.
Four, criterion of therapeutical effect: the efficacy assessment standard with reference to climacteric syndrome in People's Republic of China's traditional Chinese medicine industry standard " Chinese medical disease Standardization of diagnosis and curative effect ":
1, cure: warm, sweating, the transference cure such as agitation, feel comfortable;
2, take a turn for the better: warm, sweating, the symptom such as agitation alleviate;
3, invalid: after taking medicine, the state of an illness is unchanged.
Five, therapeutic effect: in this clinical observation case, takes medicine 3-6 the course for the treatment of, and recovery from illness 55 example, follows up a case by regular visits to and have no recurrence; Take a turn for the better 19 examples, invalid 6 examples.There is not toxic and side effects in treatments period.
Six, model case:
Case 1:
In certain, female, 46 years old.Patient's readme: occurred menstruation before half a year successively irregularly, and irritated with emotion, and dizziness and tinnitus, hectic fever hyperhidrosis, soreness of waist frequent micturition, dream is many easily wakes up.Examine and see: pale complexion, light red tongue, tongue are white, deep-thready pulse.Be diagnosed as: climacteric syndrome.Take 2 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, symptom obviously alleviates, and the soreness of waist is weak, and vexed insomnia obviously improves, and perspires and reduces; Continue to take 2 courses for the treatment of, recovery from illness.Follow up a case by regular visits to and have no recurrence half a year.
Case 2:
Grandson, female, 45 years old.Patient's readme: cycle disorder in the period, 1, dizziness, cardiopalmus, forgetful, insomnia, tinnitus, warm perspiration, irritable.Once the Drug therapys such as nilestriol were taken, but poor effect.Examine and see: light red tongue, the micro-Huang of thin lingual fur, stringy and thready pulse.Take 2 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, symptom is clearly better; Continue to take 3 courses for the treatment of, warm, sweating, the transference cure such as agitation, recovery from illness.
Claims (1)
1. treat a Chinese medicine composition for climacteric syndrome, it is characterized in that: its raw material of Chinese medicine and weight proportion are: Cortex Moutan 12g, Fructus Gardeniae 15g, Radix Bupleuri 15g, Radix Angelicae Sinensis 20g, Rhizoma Atractylodis Macrocephalae 30g, Radix Paeoniae Alba 30g, Poria 20g, Radix Platycodonis 10g, Radix Aucklandiae 10g, Pericarpium Citri Reticulatae Viride 15g, Pericarpium Citri Reticulatae 15g, Rhizoma Pinelliae 10g, Semen Raphani 10g, Fructus Amomi 10g, Fructus Akebiae 15g, Fructus Aurantii Immaturus 10g, Radix Morindae Officinalis 10g, Herba Epimedii 30g, Radix Curcumae 15g, Rhizoma Cyperi 10g, Herba Menthae 10g, Retinervus Luffae Fructus 10g, Fructus Tribuli 10g, Rhizoma Chuanxiong 20g, Rhizoma Corydalis 20g, Radix Glycyrrhizae 6g.
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