CN103330964B - With the artificial heart system of blood pressure regulating mechanism - Google Patents
With the artificial heart system of blood pressure regulating mechanism Download PDFInfo
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- 210000004369 blood Anatomy 0.000 claims abstract description 86
- 239000008280 blood Substances 0.000 claims abstract description 86
- 230000000740 bleeding effect Effects 0.000 claims abstract description 36
- 210000004204 blood vessel Anatomy 0.000 claims abstract description 29
- 239000012528 membrane Substances 0.000 claims abstract description 12
- 210000003437 trachea Anatomy 0.000 claims abstract description 9
- 230000036772 blood pressure Effects 0.000 claims abstract description 7
- 230000007246 mechanism Effects 0.000 claims abstract description 5
- 230000001105 regulatory effect Effects 0.000 claims abstract description 5
- 238000007789 sealing Methods 0.000 claims abstract description 4
- 238000011144 upstream manufacturing Methods 0.000 claims description 3
- 230000007423 decrease Effects 0.000 abstract description 4
- 230000000747 cardiac effect Effects 0.000 abstract description 3
- 230000017531 blood circulation Effects 0.000 description 5
- 206010019280 Heart failures Diseases 0.000 description 4
- 238000005516 engineering process Methods 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 238000002054 transplantation Methods 0.000 description 2
- 206010020772 Hypertension Diseases 0.000 description 1
- 208000019269 advanced heart failure Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 210000002837 heart atrium Anatomy 0.000 description 1
- 238000011017 operating method Methods 0.000 description 1
- 238000005086 pumping Methods 0.000 description 1
- 238000011282 treatment Methods 0.000 description 1
- 230000002861 ventricular Effects 0.000 description 1
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Abstract
一种生物医学工程领域的带有血压调节机构的人工心脏系统，包括进血管、单向阀、气管、人工心脏、出血管、进血支管、出血支管、心脏薄膜、容积腔、移动体和弹性部件，心脏薄膜把人工心脏气体腔和血液腔，进血支管的出口与血液腔的右侧相连通，出血支管的进口与血液腔的左侧相连通，移动体安装在容积腔内并与容积腔的内壁面密封接触，移动体的右壁面通过弹性部件与容积腔的右壁面相连接。当进血管压力较高时，移动体向右移动，进入血液腔的血液减少；当进血管压力较低时，移动体向左移动，进入血液腔的血液增多。本发明设计合理，结构简单，适用于对血压较为敏感的病人的人工心脏系统。
An artificial heart system with a blood pressure regulating mechanism in the field of biomedical engineering, including blood inlet, one-way valve, trachea, artificial heart, outlet blood vessel, blood inlet branch, outflow branch, cardiac membrane, volume chamber, mobile body and elasticity Components, the heart membrane connects the gas cavity and the blood cavity of the artificial heart, the outlet of the blood inlet branch is connected with the right side of the blood cavity, the inlet of the bleeding branch is connected with the left side of the blood cavity, and the moving body is installed in the volume cavity and connected with the volume The inner wall of the cavity is in sealing contact, and the right wall of the moving body is connected with the right wall of the volume cavity through the elastic component. When the pressure of the blood vessel is high, the moving body moves to the right, and the blood entering the blood cavity decreases; when the pressure of the blood vessel is low, the moving body moves to the left, and the blood entering the blood cavity increases. The invention has reasonable design and simple structure, and is suitable for the artificial heart system of patients who are sensitive to blood pressure.
Description
技术领域technical field
本发明涉及的是一种生物医学工程领域的人工心脏系统，特别是一种带有血压调节机构的人工心脏系统。The invention relates to an artificial heart system in the field of biomedical engineering, in particular to an artificial heart system with a blood pressure regulating mechanism.
背景技术Background technique
人工心脏，即用生物机械手段部分或完全替代心脏的泵血机能，维持全身的血液循环。按功能划分包括心室辅助血泵和全人工心脏。人工心脏移植为一种治疗心衰的手段，是心脏移植术有效的替代方案。全人工心脏是一种用于代替心脏下部两个腔室的设备。这两个被替代的腔室被称为“心室”。如果一个病患由于心力衰竭到了晚期而导致两个心室都无法再发挥功能，就可能会利用到这种设备。心力衰竭是指心脏由于受到损害或削弱而导致无力输送足够的血液以满足身体的需要。“晚期”是指这种心脏衰竭到了一定十分严重的程度，以至于除了心脏移植之外的所有其他治疗都无法起效了。在两种情况下，患者可能需要全人工心脏：患者可能需要全人工心脏来维持生命指导能够获得移植的心脏；不具备心脏移植的资格，但已经到了两个心室逐渐丧失功能的心力衰竭晚期；全人工心脏和患者的心房相接。人工心脏技术是一种非常先进的生物医学技术，随着现代社会心脏病人的逐渐增加，人工心脏技术将会有着非常广阔的应用前景。The artificial heart is to partially or completely replace the pumping function of the heart with biomechanical means to maintain blood circulation throughout the body. Divided by function, it includes ventricular assist blood pump and total artificial heart. Artificial heart transplantation is a means of treating heart failure and an effective alternative to heart transplantation. A total artificial heart is a device used to replace the lower two chambers of the heart. These two replaced chambers are called "ventricles". This device may be used if a patient has advanced heart failure where both ventricles are no longer functioning. Heart failure is the inability of the heart to pump enough blood to meet the body's needs because it is damaged or weakened. "Advanced" means that the heart failure is so severe that all other treatments other than a heart transplant are ineffective. There are two situations in which a patient may need a total artificial heart: the patient may need a total artificial heart to sustain life until a transplantable heart is available; the patient is not eligible for a heart transplant but has reached an advanced stage of heart failure where both ventricles are gradually losing function; The total artificial heart is attached to the patient's atrium. Artificial heart technology is a very advanced biomedical technology. With the gradual increase of heart patients in modern society, artificial heart technology will have a very broad application prospect.
经过对现有技术文献的检索发现，中国专利号99126700.1，专利名称：气电一体式血泵、气电一体式人工心脏，该专利技术提供了血泵简单化、人工心脏小型化方案，但是它不能有效的调节人工心脏出血管的出血压力，容易造成病人的血压波动较大。After searching the existing technical literature, it was found that Chinese Patent No. 99126700.1, patent name: gas-electric integrated blood pump, gas-electric integrated artificial heart, this patent technology provides a solution for simplifying the blood pump and miniaturizing the artificial heart, but it Failure to effectively adjust the bleeding pressure of the artificial heart out of the blood vessel will easily cause the patient's blood pressure to fluctuate greatly.
发明内容Contents of the invention
本发明针对上述现有技术的不足，提供了一种带有血压调节机构的人工心脏系统，可以有效防调节人工心脏出血管的出血压力。The present invention aims at the deficiencies of the above-mentioned prior art, and provides an artificial heart system with a blood pressure regulating mechanism, which can effectively prevent and regulate the bleeding pressure of the blood vessels of the artificial heart.
本发明是通过以下技术方案来实现的，本发明包括进血管、单向阀、气管、人工心脏、出血管、第一转接头、第一进血支管、第二进血支管、第二转接头、第一出血支管、第二出血支管、心脏薄膜、连接管、第三进血支管、容积腔、移动体、弹性部件，单向阀安装在进血管中，心脏薄膜安装在人工心脏中并把人工心脏分割为气体腔和血液腔两部分，气体腔位于人工心脏的上部，气管的一端与气体腔相连通，第一转接头的进口与进血管的出口相连接，第一转接头的出口分别与第一进血支管的进口、第二进血支管的进口相连接，第三进血支管的出口、第二进血支管的出口均与血液腔的右侧相连通，第二转接头的出口与出血管的进口相连接，第二转接头的进口分别与第一出血支管的出口、第二出血支管的出口相连接，第一出血支管的进口、第二出血支管的进口均与血液腔的左侧相连通，第三进血支管的出口位于第二进血支管出口的上方，第一出血支管的进口位于第二出血支管进口的上方，连接管的进口与进血管相连通并位于单向阀的上游，连接管的出口与容积腔的左侧壁相连通，第一进血支管的出口与容积腔的下侧壁相连通，第三进血支管的进口与容积腔的上侧壁相连通，移动体安装在容积腔内并与容积腔的内壁面密封接触，移动体的右壁面通过弹性部件与容积腔的右壁面相连接。The present invention is achieved through the following technical solutions, the present invention includes blood vessel, one-way valve, trachea, artificial heart, blood vessel, first adapter, first blood inlet branch, second blood inlet branch, second adapter , the first bleeding branch, the second bleeding branch, the heart membrane, the connecting tube, the third blood inlet branch, the volume cavity, the moving body, the elastic component, the one-way valve is installed in the blood inlet, the heart membrane is installed in the artificial heart and put The artificial heart is divided into gas cavity and blood cavity. The gas cavity is located on the upper part of the artificial heart. One end of the trachea is connected to the gas cavity. The inlet of the first adapter is connected to the outlet of the blood vessel. The outlets of the first adapter are respectively It is connected with the inlet of the first blood inlet branch and the inlet of the second blood inlet branch, the outlet of the third blood inlet branch and the outlet of the second blood inlet branch are all connected to the right side of the blood cavity, and the outlet of the second adapter It is connected with the inlet of the blood vessel, and the inlet of the second adapter is respectively connected with the outlet of the first bleeding branch and the outlet of the second bleeding branch, and the inlet of the first bleeding branch and the inlet of the second bleeding branch are connected with the blood cavity The left side is connected, the outlet of the third blood-inlet branch is above the outlet of the second blood-inlet branch, the inlet of the first outflow branch is above the inlet of the second outflow branch, and the inlet of the connecting pipe is connected with the blood-inlet and located in a one-way Upstream of the valve, the outlet of the connecting pipe is connected with the left side wall of the volume chamber, the outlet of the first blood inlet branch is connected with the lower side wall of the volume chamber, and the inlet of the third blood inlet branch is connected with the upper side wall of the volume chamber Generally, the moving body is installed in the volume cavity and is in sealing contact with the inner wall of the volume cavity, and the right wall of the moving body is connected with the right wall of the volume cavity through elastic components.
进一步地，在本发明中第一进血支管、第二进血支管、第三进血支管、第一出血支管、第二出血支管的内径均相同，容积腔的横截面为长方形，弹性部件为弹簧。Further, in the present invention, the inner diameters of the first blood-inlet branch, the second blood-inlet branch, the third blood-inlet branch, the first outflow branch, and the second outflow branch are all the same, the cross-section of the volume cavity is rectangular, and the elastic member is spring.
在本发明的工作过程中，气管和气源相连接，当气体腔内的压力较小时，心脏薄膜向上弹起，血液腔的容积变大、压力变小，进血管中的单向阀打开，血液经过第一进血支管、第二进血支管和第三进血支管流入血液腔；当气体腔内的压力较大时，心脏薄膜向下弹起，血液腔的容积变小、压力变大，进血管中的单向阀关闭，血液经过第一出血支管和第二出血支管流出血液腔。当进血管内压力较大时，移动体左侧的容积腔内压力也较大，移动体向右移动并压缩弹性部件，流经第三进血支管的血量减少，从而使出血管的出血压力变小；当进血管内压力较小时，移动体左侧的容积腔内压力也较小，在弹性部件的作用下移动体向左移动，流经第三进血支管的血量增大，从而使出血管的出血压力恢复正常。In the working process of the present invention, the trachea is connected with the gas source, and when the pressure in the gas chamber is small, the heart membrane bounces upward, the volume of the blood chamber becomes larger and the pressure becomes smaller, and the one-way valve in the blood vessel opens, The blood flows into the blood chamber through the first blood inlet branch, the second blood inlet branch and the third blood inlet branch; when the pressure in the gas chamber is high, the heart membrane bounces downward, and the volume of the blood chamber decreases and the pressure increases , the one-way valve in the blood vessel is closed, and the blood flows out of the blood cavity through the first bleeding branch and the second bleeding branch. When the pressure in the blood vessel is high, the pressure in the volume cavity on the left side of the moving body is also high, and the moving body moves to the right and compresses the elastic part, and the blood volume flowing through the third blood-inlet branch decreases, thereby causing the bleeding of the out-of-vessel The pressure becomes smaller; when the pressure in the blood vessel is small, the pressure in the volume cavity on the left side of the mobile body is also small, and the mobile body moves to the left under the action of the elastic component, and the blood volume flowing through the third blood vessel branch increases. Thereby, the bleeding pressure of the blood vessels returns to normal.
与现有技术相比，本发明具有如下有益效果：本发明通过改变进入血液腔的血液流量，可以实现出血管出血压力的自我调节，从而使出血压力在进血压力较高的情况下也能维持稳定；本发明设计合理，结构简单，具有较广的应用前景。Compared with the prior art, the present invention has the following beneficial effects: the present invention can realize the self-regulation of the bleeding pressure of the blood vessel by changing the blood flow entering the blood cavity, so that the bleeding pressure can also be adjusted under the condition of high blood pressure. Maintain stability; the invention has reasonable design, simple structure and broad application prospects.
附图说明Description of drawings
图1为本发明的结构示意图；Fig. 1 is a structural representation of the present invention;
图2为图1的局部放大图；Figure 2 is a partially enlarged view of Figure 1;
图3为图1中A－A剖面的结构示意图；Fig. 3 is a structural schematic diagram of section A-A in Fig. 1;
其中：1、进血管，2、单向阀，3、气管，4、人工心脏，5、出血管，6、第一转接头，7、第一进血支管，8、第二进血支管，9、第二转接头，10、第一出血支管，11、第二出血支管，12、心脏薄膜，13、气体腔，14、血液腔，15、连接管，16、第三进血支管，17、容积腔，18、移动体，19、弹性部件。Among them: 1. Inlet blood vessel, 2. One-way valve, 3. Trachea, 4. Artificial heart, 5. Outlet blood vessel, 6. First adapter, 7. First blood inlet branch, 8. Second blood inlet branch, 9. Second adapter, 10. First bleeding branch, 11. Second bleeding branch, 12. Cardiac membrane, 13. Gas chamber, 14. Blood chamber, 15. Connecting tube, 16. Third blood inlet branch, 17 , volume cavity, 18, mobile body, 19, elastic component.
具体实施方式Detailed ways
下面结合附图对本发明的实施例作详细说明，本实施例以本发明技术方案为前提，给出了详细的实施方式和具体的操作过程，但本发明的保护范围不限于下述的实施例。The embodiments of the present invention will be described in detail below in conjunction with the accompanying drawings. This embodiment is based on the technical solution of the present invention, and provides detailed implementation methods and specific operating procedures, but the scope of protection of the present invention is not limited to the following embodiments. .
实施例Example
如图1所示，本发明包括进血管1、单向阀2、气管3、人工心脏4、出血管5、第一转接头6、第一进血支管7、第二进血支管8、第二转接头9、第一出血支管10、第二出血支管11、心脏薄膜12、连接管15、第三进血支管16、容积腔17、移动体18和弹性部件19，单向阀2安装在进血管1中，心脏薄膜12安装在人工心脏4中并把人工心脏4分割为气体腔13和血液腔14两部分，气体腔13位于人工心脏4的上部，气管3的一端与气体腔13相连通，第一转接头6的进口与进血管1的出口相连接，第一转接头6的出口分别与第一进血支管7的进口、第二进血支管8的进口相连接，第三进血支管16的出口、第二进血支管8的出口均与血液腔14的右侧相连通，第二转接头9的出口与出血管5的进口相连接，第二转接头9的进口分别与第一出血支管10的出口、第二出血支管11的出口相连接，第一出血支管10的进口、第二出血支管11的进口均与血液腔14的左侧相连通，第三进血支管16的出口位于第二进血支管8出口的上方，第一出血支管10的进口位于第二出血支管11进口的上方，连接管15的进口与进血管1相连通并位于单向阀2的上游，连接管15的出口与容积腔17的左侧壁相连通，第一进血支管7的出口与容积腔17的下侧壁相连通，第三进血支管16的进口与容积腔17的上侧壁相连通，移动体18安装在容积腔17内并与容积腔17的内壁面密封接触，移动体18的右壁面通过弹性部件19与容积腔17的右壁面相连接，第一进血支管7、第二进血支管8、第三进血支管16、第一出血支管10、第二出血支管11的内径均相同，容积腔17的横截面为长方形，弹性部件19为弹簧。As shown in Figure 1, the present invention includes an inlet blood vessel 1, a one-way valve 2, a trachea 3, an artificial heart 4, an outlet vessel 5, a first adapter 6, a first blood inlet branch 7, a second blood inlet branch 8, a first Two adapters 9, the first bleeding branch pipe 10, the second bleeding branch pipe 11, the cardiac membrane 12, the connecting pipe 15, the third blood inlet branch pipe 16, the volume cavity 17, the moving body 18 and the elastic member 19, and the one-way valve 2 is installed on Into the blood vessel 1, the heart membrane 12 is installed in the artificial heart 4 and divides the artificial heart 4 into two parts, the gas cavity 13 and the blood cavity 14, the gas cavity 13 is located on the upper part of the artificial heart 4, and one end of the trachea 3 is connected with the gas cavity 13 Through, the inlet of the first adapter 6 is connected with the outlet of the blood inlet 1, the outlet of the first adapter 6 is respectively connected with the inlet of the first blood inlet branch 7 and the inlet of the second blood inlet branch 8, and the third inlet The outlet of the blood branch pipe 16 and the outlet of the second blood inlet branch pipe 8 are all connected with the right side of the blood chamber 14, the outlet of the second adapter 9 is connected with the inlet of the outlet blood vessel 5, and the inlet of the second adapter 9 is respectively connected with the The outlet of the first bleeding branch 10 and the outlet of the second bleeding branch 11 are connected, the inlet of the first bleeding branch 10 and the inlet of the second bleeding branch 11 are all connected to the left side of the blood cavity 14, and the third blood inlet branch 16 The outlet of the first bleeding branch is located above the outlet of the second blood inlet branch 8, the inlet of the first bleeding branch 10 is located above the entrance of the second bleeding branch 11, and the inlet of the connecting pipe 15 communicates with the inlet blood vessel 1 and is located upstream of the one-way valve 2. The outlet of the connecting pipe 15 communicates with the left side wall of the volume chamber 17, the outlet of the first blood inlet branch pipe 7 communicates with the lower side wall of the volume chamber 17, and the inlet of the third blood inlet branch pipe 16 communicates with the upper side of the volume chamber 17. The wall is connected, the moving body 18 is installed in the volume cavity 17 and is in sealing contact with the inner wall of the volume cavity 17, the right wall of the moving body 18 is connected with the right wall of the volume cavity 17 through the elastic member 19, the first blood inlet branch 7 The inner diameters of the second blood inlet branch 8, the third blood inlet branch 16, the first outflow branch 10, and the second outflow branch 11 are all the same, the cross section of the volume chamber 17 is rectangular, and the elastic member 19 is a spring.
在本发明的工作过程中，当气体腔13内的压力较小时，心脏薄膜12向上弹起，血液腔14的容积变大、压力变小，进血管1中的单向阀2打开，血液经过第一进血支管7、第二进血支管8和第三进血支管16流入血液腔14；当气体腔13内的压力较大时，心脏薄膜12向下弹起，血液腔14的容积变小、压力变大，进血管1中的单向阀2关闭，血液经过第一出血支管7和第二出血支管8流出血液腔14。当进血管1内压力较大时，移动体18左侧的容积腔17内压力也较大，移动体18向右移动并压缩弹性部件19，流经第三进血支管16的血量减少，从而使出血管5的出血压力变小；当进血管1内压力较小时，移动体18左侧的容积腔17内压力也较小，在弹性部件19的作用下移动体18向左移动，流经第三进血支管16的血量增大，从而使出血管5的出血压力恢复正常。In the working process of the present invention, when the pressure in the gas chamber 13 is small, the heart membrane 12 bounces upward, the volume of the blood chamber 14 becomes larger and the pressure becomes smaller, the one-way valve 2 in the blood vessel 1 is opened, and the blood passes through The first blood inlet branch pipe 7, the second blood inlet branch pipe 8 and the third blood inlet branch pipe 16 flow into the blood chamber 14; when the pressure in the gas chamber 13 is high, the heart membrane 12 bounces downward, and the volume of the blood chamber 14 becomes larger. When the pressure increases, the one-way valve 2 in the blood vessel 1 is closed, and the blood flows out of the blood cavity 14 through the first bleeding branch 7 and the second bleeding branch 8 . When the pressure in the blood vessel 1 is high, the pressure in the volume cavity 17 on the left side of the moving body 18 is also high, the moving body 18 moves to the right and compresses the elastic member 19, and the blood volume flowing through the third blood-inlet branch 16 decreases. Thereby the bleeding pressure of the blood vessel 5 is reduced; when the pressure in the blood vessel 1 is small, the pressure in the volume chamber 17 on the left side of the moving body 18 is also small, and the moving body 18 moves to the left under the action of the elastic member 19, and the flow The blood volume through the third blood inlet branch 16 increases, so that the bleeding pressure of the outlet blood vessel 5 returns to normal.
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|---|---|---|---|---|
| GB1532719A (en) * | 1976-01-09 | 1978-11-22 | Thermo Electron Corp | Blood circulatory assist device and control therefor |
| CN85101745A (en) * | 1985-04-01 | 1987-01-31 | 艾斯特勒科技公司 | The artificial heart |
| FR2606283A1 (en) * | 1986-11-07 | 1988-05-13 | Guilmet Daniel | Artificial heart |
| US5089018A (en) * | 1987-01-27 | 1992-02-18 | Didier Lapeyre | Total heat prosthesis |
| CN1256157A (en) * | 1999-11-22 | 2000-06-14 | 李树文 | Pneumatic blood pump, combined pneumatic heart-lung machine and artificial pneumatic heart |
| CN2838630Y (en) * | 2005-11-04 | 2006-11-22 | 广东省心血管病研究所 | Pneumatic left cardic auxiliary pump |
| CN201558364U (en) * | 2009-12-10 | 2010-08-25 | 王仁忠 | Intra-abdominal left ventricle assisting pump |
-
2013
- 2013-05-31 CN CN201310215507.4A patent/CN103330964B/en not_active Expired - Fee Related
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1532719A (en) * | 1976-01-09 | 1978-11-22 | Thermo Electron Corp | Blood circulatory assist device and control therefor |
| CN85101745A (en) * | 1985-04-01 | 1987-01-31 | 艾斯特勒科技公司 | The artificial heart |
| FR2606283A1 (en) * | 1986-11-07 | 1988-05-13 | Guilmet Daniel | Artificial heart |
| US5089018A (en) * | 1987-01-27 | 1992-02-18 | Didier Lapeyre | Total heat prosthesis |
| CN1256157A (en) * | 1999-11-22 | 2000-06-14 | 李树文 | Pneumatic blood pump, combined pneumatic heart-lung machine and artificial pneumatic heart |
| CN2838630Y (en) * | 2005-11-04 | 2006-11-22 | 广东省心血管病研究所 | Pneumatic left cardic auxiliary pump |
| CN201558364U (en) * | 2009-12-10 | 2010-08-25 | 王仁忠 | Intra-abdominal left ventricle assisting pump |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103330964A (en) | 2013-10-02 |
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