CN103320960A - Method for manufacturing artificial blood vessel - Google Patents
Method for manufacturing artificial blood vessel Download PDFInfo
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- CN103320960A CN103320960A CN2013102659860A CN201310265986A CN103320960A CN 103320960 A CN103320960 A CN 103320960A CN 2013102659860 A CN2013102659860 A CN 2013102659860A CN 201310265986 A CN201310265986 A CN 201310265986A CN 103320960 A CN103320960 A CN 103320960A
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Abstract
The invention discloses a method for manufacturing an artificial blood vessel. The artificial blood vessel is a cylindrical main blood vessel. The method is characterized in that the artificial blood vessel is knitted on a warp knitting machine with double needle beds, the warp knitting machine with the double needle beds is provided with at least four ground guide bars and at least twelve pattern guide bars, two pattern guide bar operating lines are arranged between each two adjacent ground guide bars, and each operating line comprises two pattern guide bars; warp yarns are strung and sleeved together by means of looping knitting actions among looping elements, the ground guide bars and the pattern guide bars, so that two netted platy fabrics comprising loops are formed on the two needle beds of the warp knitting machine; owing to looping knitting actions among the looping elements and the pattern guide bars and swinging actions of the guide bars, and the warp yarns are alternately looped on the two needle beds of the warp knitting machine, so that the two netted platy fabrics are connected with each other to form a fabric of the cylindrical main blood vessel. The method has the advantages that the artificial blood vessel which is knitted by the method has functions of promoting cell tissue ingrowth and preventing blood from permeating from the wall of the vessel during surgery, and the method can be used for knitting various blood vessel structures.
Description
Technical field
The present invention relates to a kind of artificial blood vessel that uses in human body or animal body, particularly relate to the production method of artificial blood vessel.
Background technology
In the 50's of 20th century, since observing cell after the phenomenon that the silk thread of immersion blood is grown, begun the manufacturing history of Weave type artificial blood vessel.Since then, select suitable fibrous material and desirable fabric construction to become the emphasis of artificial blood vessel research.Today, it is clinical that oneself is widely used in Weave type artificial blood vessel, replaces the blood vessel that has damaged in the human body, obtains the good medical treatment effect clinically.Desirable artificial blood vessel tube wall should have the hole of suitable dimension, both has been beneficial to growing into of cell tissue, can not cause a large amount of oozings of blood in the surgical procedure again because of the existence of hole.Existing Weave type artificial blood vessel generally adopts the manufacture method of tubular knitting, vascular wall is single layer structure, for fear of the tube wall oozing of blood, the method for circular knitting machine is the tightness degree that increases the tube wall textile structural, and human cell tissue grew into after this method was unfavorable for performing the operation.Though woven blood vessel's fabric has the advantage that tissue tight, intensity height, voidage are low, need not to coagulate in advance, its poor compliance, the limit of easily loosing, healing effect is undesirable.The shortcoming of weft knitting artificial blood vessel fabric is easy crimping, the easy running of vertical and horizontal, and elasticity is restorative poor, can take place behind the implant into body slowly radially and vertically creep.Therefore, though it is clinical that Weave type artificial blood vessel has been widely used in, but promote cell tissue to grow into and the function of tube wall oozing of blood when avoiding performing the operation owing to will take into account simultaneously, seeking desirable production method still is the problem of replacement type blood vessel research and development in recent years with the Weave type artificial blood vessel that obtains suitable tube wall hole.
Summary of the invention
The technical problem to be solved in the present invention provides a kind of can taking into account simultaneously and promotes cell tissue to grow into and the production method of the artificial blood vessel of tube wall oozing of blood when avoiding performing the operation.
For solving the problems of the technologies described above, the present invention can adopt a kind of like this production method of artificial blood vessel, described artificial blood vessel is cylindric main blood vessel, weave at double rib warp loom, described double rib warp loom configuration at least four is ground sley bar and at least ten two flower sley bars, adjacent two ground two barriness sley bar active lines of arranging between the sley bars, every active line comprises two colored sley bars; On two needle-bars of warp knitting machine respectively by loop-forming element and ground sley bar, the lopping braiding of flower between the sley bar, the warp thread string is nested together forms two net slice shape fabrics that are made of coil; Weaving by the lopping between loop-forming element and the flower sley bar respectively on two needle-bars of warp knitting machine and simultaneously by the sley bar swing, making warp thread replace lopping at two needle-bars described two net slice shape fabrics are connected and composed cylindric main blood vessel tricot.
For solving the problems of the technologies described above, the present invention also can adopt a kind of like this production method of artificial blood vessel, described artificial blood vessel is the branch type artificial blood vessel that has cylindric branch vessel on the cylindric main blood vessel, weave at double rib warp loom, described double rib warp loom configuration at least four is ground sley bar and at least ten two flower sley bars, adjacent two ground two barriness sley bar active lines of arranging between the sley bars, every active line comprises two colored sley bars;
When the cylindric main blood vessel of braiding, on two needle-bars of warp knitting machine respectively by the lopping braiding between loop-forming element and ground sley bar, the flower sley bar, with warp thread string two the net slice shape fabrics that constituted by coil of formation that are nested together; Weaving by the lopping between loop-forming element and the flower sley bar respectively on two needle-bars of warp knitting machine and simultaneously by the sley bar swing, making warp thread replace lopping at two needle-bars described two net slice shape fabrics are connected and composed cylindric main blood vessel tricot;
When the cylindric main blood vessel of braiding and upper bifurcation part branch vessel thereof, on two needle-bars of warp knitting machine respectively by loop-forming element and ground sley bar, the lopping braiding of flower between the sley bar, with the warp thread string be nested together form two that constituted by coil, with above-mentioned main blood vessel in the continuous net slice shape master blood vessel fabric of net slice shape fabric; On two needle-bars of warp knitting machine respectively by in loop-forming element and every the active line wherein one the lopping braiding between the flower sley bar and by the sley bar swing, alternately lopping will described two net slice shape master blood vessel fabrics connection at two needle-bars to make warp thread; On two needle-bars of warp knitting machine respectively by loop-forming element and ground between the sley bar the lopping braiding and by the sley bar swing, make warp thread two needle-bars alternately lopping constitute respectively and described two net slice shape branch vessel fabrics that net slice shape master blood vessel fabric links to each other; On two needle-bars of warp knitting machine, swing the lopping braiding between the flower sley bar and by sley bar by other one in loop-forming element and every the active line respectively, make warp thread replace lopping at two needle-bars described net slice shape branch vessel fabric is connected, constitute the branch type artificial blood vessel that has cylindric branch vessel on the cylindric main blood vessel.
As a preferred embodiment of the present invention, the flower sley bar, totally ten six sley bar ground sley bar and 12 in double rib warp loom configuration four, the two barriness sley bar active lines of arranging between adjacent two ground sley bars, and every active line comprises two colored sley bars.
After adopting aforementioned production method, the present invention has following beneficial effect:
Artificial blood vessel by the aforementioned production method braiding is compared with the woven blood vessel, has the advantage that compliance is good, be difficult for diffusing limit; Compare with weft-knitted artificial blood vessel, have the physical dimension good stability, be difficult for producing crimping and decoherencing, be easy to the characteristics of surgical procedure and stitching.
Artificial blood vessel fabric by the aforementioned production method braiding has double-layered structure, the fabric outer warp knit structure is through the suede tissue, the inner textile layer warp knit structure is warp plain stitch, constitute the structural pipe wall of an integral body, tube wall oozing of blood when this double-deck artificial blood vessel can prevent from performing the operation, be conducive to perform the operation the growing into smoothly of back cell tissue has to take into account simultaneously and promotes cell tissue to grow into and the function of tube wall oozing of blood when avoiding performing the operation.
Artificial blood vessel by the aforementioned production method braiding has enough mechanical performances, satisfies the requirement of mechanical performance in curl processing and the operation technique.
Adopt aforementioned production method, can weave diversified blood vessel structure, braiding has blood vessel structure and the less blood vessel of braided diameter of a plurality of bifurcateds.
Description of drawings
Below in conjunction with accompanying drawing the specific embodiment of the present invention is described in further detail.
Fig. 1 is a kind of schematic diagram of inventor's hematopoiesis pipe production method.
Fig. 2 is a kind of structural representation of artificial blood vessel fabric among the present invention.
Fig. 3 is the schematic diagram that passes of fused braid blood vessel's fabric.
The specific embodiment
Production method referring to a kind of artificial blood vessel shown in Figure 1, described artificial blood vessel is cylindric main blood vessel, weave at double rib warp loom, described double rib warp loom configuration at least four is ground sley bar and at least ten two flower sley bars, adjacent two ground two barriness sley bar active lines of arranging between the sley bars, every active line comprises two colored sley bars; On two needle-bars of warp knitting machine respectively by loop-forming element and ground sley bar, the lopping braiding of flower between the sley bar, the warp thread string is nested together forms two net slice shape fabrics that are made of coil; Weaving by the lopping between loop-forming element and the flower sley bar respectively on two needle-bars of warp knitting machine and simultaneously by the sley bar swing, making warp thread replace lopping at two needle-bars described two net slice shape fabrics are connected and composed cylindric main blood vessel tricot.
As shown in Figure 1, double rib warp loom preferred disposition four is ground sley bar and 12 flower sley bars, totally ten six sley bar, each sley bar is installed on the sley bar seat 17 and according to following rule and arranges, 1st, 6,11,16 sley bars are the ground sley bar, 2nd, 3,4,5,7,8,9,10,12,13,14,15 combs are colored sley bar, and sley bar is in 17 one-tenth symmetry arrangement of sley bar seat; When the cylindric main blood vessel of braiding, sinker 18 before on two needle-bars of warp knitting machine by loop-forming element being respectively, preceding knitting needle 19 and preceding knocking over pin 20 and back sinker 21, back knitting needle 22 and back knocking over pin 23 and ground sley bar 1,6,11,16, flower sley bar 2,5,8,9,13, lopping braiding between 15, the warp thread string is nested together forms two net slice shape fabrics 24 that constituted by coil, at this moment, flower sley bar 2,5,8,9,13,15 serve as ground comb effect, be used for filling the part of ground comb vacancy, ground sley bar 1,6 and the flower sley bar 2,5,8 in preceding needle-bar lopping, ground sley bar 11,16 and the flower sley bar 9,13,15 in back needle-bar lopping, flower sley bar 8 is filled the vacancy part of ground sley bar 6, flower sley bar 9 is filled the vacancy part of ground sley bar 11, flower sley bar 2,5 fill the vacancy part of ground sley bar 1, flower sley bar 13,15 fill the vacancy part of ground sley bar 16.Lopping before on two needle-bars of warp knitting machine by loop-forming element being respectively between sinker 18, preceding knitting needle 19 and preceding knocking over pin 20 and back sinker 21, back knitting needle 22 and back knocking over pin 23 and the flower sley bar 3,4,7,10,12,14 weaves and swings by sley bar simultaneously, make warp thread replace lopping at two needle-bars described two net slice shape fabrics 24 are connected and composed cylindric main blood vessel tricot, at this moment, spend sley bar 3,4,7,10,12,14 all lopping on the needle-bar of front and back.
Referring to the production method of Fig. 1 to a kind of artificial blood vessel shown in Figure 3, described artificial blood vessel is the branch type artificial blood vessel that has cylindric branch vessel B on the cylindric main blood vessel A, weave at double rib warp loom, described double rib warp loom configuration at least four is ground sley bar and at least ten two flower sley bars, adjacent two ground two barriness sley bar active lines of arranging between the sley bars, every active line comprises two colored sley bars; When the cylindric main blood vessel of braiding, on two needle-bars of warp knitting machine respectively by the lopping braiding between loop-forming element and ground sley bar, the flower sley bar, with warp thread string two the net slice shape fabrics that constituted by coil of formation that are nested together; Weaving by the lopping between loop-forming element and the flower sley bar respectively on two needle-bars of warp knitting machine and simultaneously by the sley bar swing, making warp thread replace lopping at two needle-bars described two net slice shape fabrics are connected and composed cylindric main blood vessel tricot; When the cylindric main blood vessel of braiding and upper bifurcation part branch vessel thereof, on two needle-bars of warp knitting machine respectively by loop-forming element and ground sley bar, the lopping braiding of flower between the sley bar, with the warp thread string be nested together form two that constituted by coil, with above-mentioned main blood vessel in the continuous net slice shape master blood vessel fabric of net slice shape fabric; On two needle-bars of warp knitting machine respectively by in loop-forming element and every the active line wherein one the lopping braiding between the flower sley bar and by the sley bar swing, alternately lopping will described two net slice shape master blood vessel fabrics connection at two needle-bars to make warp thread; On two needle-bars of warp knitting machine respectively by loop-forming element and ground between the sley bar the lopping braiding and by the sley bar swing, make warp thread two needle-bars alternately lopping constitute respectively and described two net slice shape branch vessel fabrics that net slice shape master blood vessel fabric links to each other; On two needle-bars of warp knitting machine, swing the lopping braiding between the flower sley bar and by sley bar by other one in loop-forming element and every the active line respectively, make warp thread replace lopping at two needle-bars described net slice shape branch vessel fabric is connected, constitute the branch type artificial blood vessel that has cylindric branch vessel on the cylindric main blood vessel.
Shown in Fig. 1,3, double rib warp loom preferred disposition four is ground sley bar and 12 flower sley bars, totally ten six sley bar, each sley bar is installed on the sley bar seat 17 and according to following rule and arranges, 1st, 6,11,16 sley bars are the ground sley bar, 2nd, 3,4,5,7,8,9,10,12,13,14,15 combs are colored sley bar, and sley bar is in 17 one-tenth symmetry arrangement of sley bar seat; As shown in Figure 2, cylindric main blood vessel A comprises the cylindric main blood vessel A of no branch vessel B
1Part and the cylindric main blood vessel A that has branch vessel B
2Part.Cylindric main blood vessel A at the no branch vessel B of braiding
1During part, sinker 18 before on two needle-bars of warp knitting machine by loop-forming element being respectively, preceding knitting needle 19 and preceding knocking over pin 20 and back sinker 21, back knitting needle 22 and back knocking over pin 23 and ground sley bar 1,6,11,16, flower sley bar 2,5,8,9,13, lopping braiding between 15, the warp thread string is nested together forms two net slice shape fabrics 24 that constituted by coil, at this moment, flower sley bar 2,5,8,9,13,15 serve as ground comb effect, be used for filling the part of ground comb vacancy, ground sley bar 1,6 and the flower sley bar 2,5,8 in preceding needle-bar lopping, ground sley bar 11,16 and the flower sley bar 9,13,15 in back needle-bar lopping, flower sley bar 8 is filled the vacancy part of ground sley bar 6, flower sley bar 9 is filled the vacancy part of ground sley bar 11, flower sley bar 2,5 fill the vacancy part of ground sley bar 1, flower sley bar 13,15 fill the vacancy part of ground sley bar 16.Lopping before on two needle-bars of warp knitting machine by loop-forming element being respectively between sinker 18, preceding knitting needle 19 and preceding knocking over pin 20 and back sinker 21, back knitting needle 22 and back knocking over pin 23 and the flower sley bar 3,4,7,10,12,14 weaves and swings by sley bar simultaneously, make warp thread replace lopping at two needle-bars described two net slice shape fabrics 24 are connected and composed cylindric main blood vessel tricot, at this moment, spend sley bar 3,4,7,10,12,14 all lopping on the needle-bar of front and back.
At the cylindric main blood vessel A of braiding
2And during upper bifurcation part branch vessel B, on two needle-bars of warp knitting machine respectively by loop-forming element namely before lopping braiding between sinker 18, preceding knitting needle 19 and preceding knocking over pin 20 and back sinker 21, back knitting needle 22 and back knocking over pin 23 and ground sley bar 1,6,11,16, the flower sley bar 2,5,8,9,13,15, with warp thread string constituted by coil, and the above-mentioned main blood vessel A of two of formation that is nested together
1In the continuous net slice shape master blood vessel fabric of net slice shape fabric 24; On two needle-bars of warp knitting machine respectively by loop-forming element namely before in sinker 18, preceding knitting needle 19 and preceding knocking over pin 20 and back sinker 21, back knitting needle 22 and back knocking over pin 23 and every the active line wherein one the lopping braiding between the flower sley bar 3,4,7,10,12,14 and by the sley bar swing, make warp thread replace lopping with described two net slice shape master blood vessel fabrics connection at two needle-bars; On two needle-bars of warp knitting machine respectively by loop-forming element namely before between sinker 18, preceding knitting needle 19 and preceding knocking over pin 20 and back sinker 21, back knitting needle 22 and back knocking over pin 23 and the ground sley bar 1,6,11,16 the lopping braiding and by the sley bar swing, make warp thread two needle-bars replace the lopping formation respectively with described two net slice shape branch vessel fabrics that net slice shape master blood vessel fabric links to each other; Sinker 18 before on two needle-bars of warp knitting machine by loop-forming element being respectively, preceding knitting needle 19 and preceding knocking over pin 20 and back sinker 21, in back knitting needle 22 and back knocking over pin 23 and every the active line other one is flower sley bar 2,5,8,9,13, lopping between 15 weaves and swings by sley bar, making warp thread replace lopping at two needle-bars links together described net slice shape branch vessel fabric, constitute the branch type artificial blood vessel that has cylindric branch vessel B on the cylindric main blood vessel A, at this moment, ground sley bar 1,6 in preceding needle-bar lopping, ground sley bar 11,16 in back needle-bar lopping, and flower sley bar 2,5,8,9,13,15 respectively in the equal lopping of front and back needle-bar.
Claims (3)
1. the production method of an artificial blood vessel, described artificial blood vessel is cylindric main blood vessel, it is characterized in that: weave at double rib warp loom, described double rib warp loom configuration at least four is ground sley bar and at least ten two flower sley bars, adjacent two ground two barriness sley bar active lines of arranging between the sley bars, every active line comprises two colored sley bars; On two needle-bars of warp knitting machine respectively by loop-forming element and ground sley bar, the lopping braiding of flower between the sley bar, the warp thread string is nested together forms two net slice shape fabrics that are made of coil; Weaving by the lopping between loop-forming element and the flower sley bar respectively on two needle-bars of warp knitting machine and simultaneously by the sley bar swing, making warp thread replace lopping at two needle-bars described two net slice shape fabrics are connected and composed cylindric main blood vessel tricot.
2. the production method of an artificial blood vessel, described artificial blood vessel is the branch type artificial blood vessel that has cylindric branch vessel on the cylindric main blood vessel, it is characterized in that: weave at double rib warp loom, described double rib warp loom configuration at least four is ground sley bar and at least ten two flower sley bars, adjacent two ground two barriness sley bar active lines of arranging between the sley bars, every active line comprises two colored sley bars;
When the cylindric main blood vessel of braiding, on two needle-bars of warp knitting machine respectively by the lopping braiding between loop-forming element and ground sley bar, the flower sley bar, with warp thread string two the net slice shape fabrics that constituted by coil of formation that are nested together; Weaving by the lopping between loop-forming element and the flower sley bar respectively on two needle-bars of warp knitting machine and simultaneously by the sley bar swing, making warp thread replace lopping at two needle-bars described two net slice shape fabrics are connected and composed cylindric main blood vessel tricot;
When the cylindric main blood vessel of braiding and upper bifurcation part branch vessel thereof, on two needle-bars of warp knitting machine respectively by loop-forming element and ground sley bar, the lopping braiding of flower between the sley bar, with the warp thread string be nested together form two that constituted by coil, with above-mentioned main blood vessel in the continuous net slice shape master blood vessel fabric of net slice shape fabric; On two needle-bars of warp knitting machine respectively by in loop-forming element and every the active line wherein one the lopping braiding between the flower sley bar and by the sley bar swing, alternately lopping will described two net slice shape master blood vessel fabrics connection at two needle-bars to make warp thread; On two needle-bars of warp knitting machine respectively by loop-forming element and ground between the sley bar the lopping braiding and by the sley bar swing, make warp thread two needle-bars alternately lopping constitute respectively and described two net slice shape branch vessel fabrics that net slice shape master blood vessel fabric links to each other; On two needle-bars of warp knitting machine, swing the lopping braiding between the flower sley bar and by sley bar by other one in loop-forming element and every the active line respectively, make warp thread replace lopping at two needle-bars described net slice shape branch vessel fabric is connected, constitute the branch type artificial blood vessel that has cylindric branch vessel on the cylindric main blood vessel.
3. the production method of artificial blood vessel according to claim 2, it is characterized in that: double rib warp loom configuration four is ground sley bar and 12 flower sley bars, totally ten six sley bar, the two barriness sley bar active lines of arranging between adjacent two ground sley bars, and every active line comprises two colored sley bars.
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| CN201310265986.0A CN103320960B (en) | 2013-06-28 | 2013-06-28 | The production method of artificial blood vessel |
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| CN103696119A (en) * | 2013-12-27 | 2014-04-02 | 常州市润源经编机械有限公司 | Artificial blood vessel knitting jacquard comb system of warp knitting machine |
| CN105369467A (en) * | 2015-10-09 | 2016-03-02 | 东华大学 | Shaping debugging method of eight pattern structures of cylindrical warp knitting machine |
| CN109477262A (en) * | 2016-06-10 | 2019-03-15 | 杜克大学 | Warp knitted fabrics for textile and medical applications and methods of making the same |
| RU2832604C1 (en) * | 2024-01-29 | 2024-12-26 | Общество с ограниченной ответственностью "Биоматериалы и клеточные технологии" | Universal mould for creating three-dimensional models of blood vessels |
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| US12018414B2 (en) | 2016-06-10 | 2024-06-25 | Duke University | Warp knit fabric for textile and medical applications and methods of manufacturing the same |
| RU2832604C1 (en) * | 2024-01-29 | 2024-12-26 | Общество с ограниченной ответственностью "Биоматериалы и клеточные технологии" | Universal mould for creating three-dimensional models of blood vessels |
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| CN103320960B (en) | 2016-01-20 |
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