CN103301326B - Medicament for treating rheumatism, rheumatoid and pain or rheumatism in lower extremities and waist - Google Patents
Medicament for treating rheumatism, rheumatoid and pain or rheumatism in lower extremities and waist Download PDFInfo
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Abstract
The invention relates to a medicament for treating rheumatism, rheumatoid and pain or rheumatism in lower extremities and waist. The medicament comprises the following substances: ginseng, cornua cervi pantotrichum, ginkgo leaf, lucid ganoderma, placenta hominis, notopterygium root, radix angelicae pubescentis, loranthus parasiticus, eucommia ulmoides, teasel root, rhizoma cibotii, large-leaved gentian, achyranthes bidentata, pawpaw, Chinese parsnip root, root of common peony, Chinese angelica, ligusticum wallichii, pseudo-ginseng, long-noded pit viper, gastrodia elata, nux vomica, saffron crocus, keel, oyster, leech, obscured homalomena rhizome, schizophragma integrifolium, garden balsam stem, ant, fructus psoraleae, radix ophiopogonis, dried rehamnnia root, white atractylodes rhizome, poria cocos, white paeony root, radix bupleuri, liquorice, hawthorn and gizzard pepsin. The medicament for treating rheumatism, rheumatoid and pain or rheumatism in lower extremities and waist has the characteristics of being low in cost, easy to prepare, small in toxic and side effect and remarkable in curative effect.
Description
Technical field
The present invention relates to tcm field, specifically, relate to a kind of medicament for the treatment of rheumatism, rheumatoid and waist lower limb arthralgia pain.
Background technology
The rheumatism cause of disease is yin-Yang disorder of QI and blood, affection of exogenous wind-cold, and pathogen is invaded meridians, the abnormality of healthy energy antagonism pathogen.Pathological changes makes joint swelling deformation, the synovial membrane muscle different pathological changes of extent of injury simultaneously, as treatment not in time, can form chronic destruction of joint, even invades internal organs and brings out other serious diseases, as rheumatic heart disease.
Orthopaedics disease has 5 percent to be due to overworked or sprain and cause, with invigorating blood circulation, the method treatment of blood stasis dispelling, pain relieving.But it will be argued that 95 percent is disorder of pectoral QI (doctor trained in Western medicine is called genetic factor and degenerates), the Liver and kidney deficiency of vital energy, stagnation of QI blood stagnation, pathogenic wind-dampness intrusion meridians waist kidney.Symptom has lumbago and skelalgia, numb flaccidity syndrome and arthralgia syndrome, difficulty in walking etc.Doctor trained in Western medicine X-ray, is called intervertebral disk hernia, hyperosteogeny, osteoporosis, arthritis etc. after CT examination, need to use differential diagnosis in tcm to treat.Because of prolonged illness must be empty, should nurse one's health pectoral qi, temperature compensation Liver and kidney, blood circulation promoting and blood stasis dispelling, wind-damp dispelling, the meridian dredging, pain relieving pain, reinforcement and elimination in combination.
Summary of the invention
The object of this invention is to provide a kind of medicament for the treatment of rheumatism, rheumatoid and waist lower limb arthralgia pain.
In order to realize object of the present invention, the invention provides one and treat rheumatism, the medicament of rheumatoid and waist lower limb arthralgia pain, the material that it comprises following weight proportioning: Radix Ginseng 10-15 part, Cornu Cervi Pantotrichum 2-4 part, Folium Ginkgo 10-15 part, Ganoderma 10-20 part, Placenta Hominis 30-50 part, Rhizoma Et Radix Notopterygii 10-20 part, Radix Angelicae Pubescentis 10-20 part, Herba Taxilli 10-30 part, Cortex Eucommiae 5-20 part, Radix Dipsaci 5-20 part, Rhizoma Cibotii 5-20 part, Radix Gentianae Macrophyllae 10-20 part, Radix Achyranthis Bidentatae 5-20 part, Fructus Chaenomelis 5-20 part, Radix Saposhnikoviae 5-20 part, Radix Paeoniae Rubra 10-20 part, Radix Angelicae Sinensis 5-20 part, Rhizoma Chuanxiong 5-20 part, Radix Notoginseng 1-5 part, Agkistrodon 200-300 part, Rhizoma Gastrodiae 5-20 part, Semen Strychni 1-5 part, Stigma Croci 1-5 part, Os Draconis 20-30 part, Concha Ostreae 20-30 part, Hirudo 30-40 part, Rhizoma Homalomenae 5-20 part, Cortex schizophragmatis integrifolii radicis 5-20 part, Herba speranskiae tuberculatae 5-20 part, Formica fusca 10-20 part, Fructus Psoraleae 1-15 part, Radix Ophiopogonis 10-15 part, Radix Rehmanniae 5-20 part, Rhizoma Atractylodis Macrocephalae 5-20 part, Poria 10-20 part, Radix Paeoniae Alba 5-20 part, Radix Bupleuri 5-20 part, Radix Glycyrrhizae 10-20 part, Fructus Crataegi 5-20 part and Endothelium Corneum Gigeriae Galli 5-20 part.
Preferably, treatment rheumatism of the present invention, the kit of rheumatoid and waist lower limb arthralgia pain contains the material of following weight proportioning: 10 parts of Radix Ginsengs, 3 parts, Cornu Cervi Pantotrichum, 15 parts of Folium Ginkgos, 15 parts of Ganodermas, 40 parts of Placenta Hominiss, 15 parts of Rhizoma Et Radix Notopterygiis, 15 parts of Radix Angelicae Pubescentiss, 20 parts of Herba Taxillis, 10 parts of the Cortexs Eucommiae, 10 parts of Radix Dipsacis, 10 parts of Rhizoma Cibotii, 15 parts of Radix Gentianae Macrophyllae, 10 parts of Radix Achyranthis Bidentataes, 10 parts of Fructus Chaenomeliss, 10 parts of Radix Saposhnikoviaes, 15 parts of Radix Paeoniae Rubra, 10 parts of Radix Angelicae Sinensis, 10 parts of Rhizoma Chuanxiongs, 3 parts of Radix Notoginseng, 250 parts of Agkistrodons, 10 parts, Rhizoma Gastrodiae, 3 parts of Semen Strychni, 3 parts of Stigma Crocis, 25 parts of Os Draconis, 25 parts of Concha Ostreaes, 35 parts of Hirudos, 10 parts of Rhizoma Homalomenaes, 10 parts of Cortex schizophragmatis integrifolii radicis, 10 parts of Herba speranskiae tuberculataes, 15 parts of Formica fuscas, 10 parts of Fructus Psoraleaes, 10 parts of Radix Ophiopogonis, 10 parts of Radix Rehmanniae, 10 parts of the Rhizoma Atractylodis Macrocephalaes, 15 parts, Poria, 10 parts of the Radix Paeoniae Albas, 10 parts of Radix Bupleuri, 15 parts, Radix Glycyrrhizae, 10 parts of 10 parts of Fructus Crataegis and Endothelium Corneum Gigeriae Galli.
More preferably, the medicament for the treatment of rheumatism of the present invention, rheumatoid and waist lower limb arthralgia pain also comprises the material of following weight proportioning: 5 parts of 5 parts of Fructus Broussonetiaes, 6 parts of 3 parts of, Herba Thlaspiss of RADIX PEUCEDANI, 5 parts of Rhizoma Smilacis Chinensiss, 7 parts of Herba Cichoriis, Rhizoma Dioscoreae Septemlobae 46 parts of Fen, Herba Siegesbeckiaes, 3 parts of Herba Gendarussaes, 5 parts of Cortex Syingae Amurensiss, 3 parts of Herba pterocephali, 3 parts of Nodus Nelumbinis Rhizomatis, 7 parts of Medulla Stachyuri (Medulla Helwingiae)s, 4 parts of Flos Bombacis Malabaricis, 5 parts of Concha Arcaes, 3 parts of Caulis Mahoniaes, 6 parts of Folium Sauropis, 7 parts of Semen Lablab Albums, 3 parts of Retinervus Luffae Fructuss, 5 parts of Herba Polygoni cymosis, 3 parts of Semen Celosiae and Fructus Litseae.
More preferably, described medicament can be tablet, dispersible tablet, oral liquid or capsule.
The medicament for the treatment of rheumatism of the present invention, rheumatoid and waist lower limb arthralgia pain has the advantages that cost is low, preparation is easy, toxic and side effects is little, curative effect is showing.
Detailed description of the invention
Embodiment 1:
Take 100 grams of Radix Ginsengs, 30 grams, Cornu Cervi Pantotrichum, 150 grams of Folium Ginkgos, 150 grams of Ganodermas, 400 grams of Placenta Hominiss, 150 grams of Rhizoma Et Radix Notopterygiis, 150 grams of Radix Angelicae Pubescentiss, 200 grams of Herba Taxillis, 100 grams of the Cortexs Eucommiae, 100 grams of Radix Dipsacis, 100 grams of Rhizoma Cibotii, 150 grams of Radix Gentianae Macrophyllae, 100 grams of Radix Achyranthis Bidentataes, 100 grams of Fructus Chaenomeliss, 100 grams of Radix Saposhnikoviaes, 150 grams of Radix Paeoniae Rubra, 100 grams of Radix Angelicae Sinensis, 100 grams of Rhizoma Chuanxiongs, 30 grams of Radix Notoginseng, 2500 grams of Agkistrodons, 100 grams, Rhizoma Gastrodiae, 30 grams of Semen Strychni, 30 grams of Stigma Crocis, 250 grams of Os Draconis, 250 grams of Concha Ostreaes, 350 grams of Hirudos, 100 grams of Rhizoma Homalomenaes, 100 grams of Cortex schizophragmatis integrifolii radicis, 100 grams of Herba speranskiae tuberculataes, 150 grams of Formica fuscas, 100 grams of Fructus Psoraleaes, 100 grams of Radix Ophiopogonis, 100 grams of Radix Rehmanniae, 100 grams of the Rhizoma Atractylodis Macrocephalaes, 150 grams, Poria, 100 grams of the Radix Paeoniae Albas, 100 grams of Radix Bupleuri, 150 grams, Radix Glycyrrhizae, 100 grams of 100 grams of Fructus Crataegis and Endothelium Corneum Gigeriae Galli, add 10000 ml waters, at 80 DEG C, heat 6 hours.Filter, it is 1.06 (60 DEG C) that filtrate is concentrated into density, is cooled to room temperature, dry.Pulverize, add 200 grams, 240 grams of microcrystalline Cellulose, 150 grams of lactose and mannitol, mix homogeneously, crosses 80 mesh sieves.Then, make soft material in spray water, cross 20 mesh sieves to granulate, dry, granulate, packs in 100 seed lac softgel shells and obtains capsule of the present invention.
Embodiment 2:
Take 100 grams of Radix Ginsengs, 30 grams, Cornu Cervi Pantotrichum, 150 grams of Folium Ginkgos, 150 grams of Ganodermas, 400 grams of Placenta Hominiss, 150 grams of Rhizoma Et Radix Notopterygiis, 150 grams of Radix Angelicae Pubescentiss, 200 grams of Herba Taxillis, 100 grams of the Cortexs Eucommiae, 100 grams of Radix Dipsacis, 100 grams of Rhizoma Cibotii, 150 grams of Radix Gentianae Macrophyllae, 100 grams of Radix Achyranthis Bidentataes, 100 grams of Fructus Chaenomeliss, 100 grams of Radix Saposhnikoviaes, 150 grams of Radix Paeoniae Rubra, 100 grams of Radix Angelicae Sinensis, 100 grams of Rhizoma Chuanxiongs, 30 grams of Radix Notoginseng, 2500 grams of Agkistrodons, 100 grams, Rhizoma Gastrodiae, 30 grams of Semen Strychni, 30 grams of Stigma Crocis, 250 grams of Os Draconis, 250 grams of Concha Ostreaes, 350 grams of Hirudos, 100 grams of Rhizoma Homalomenaes, 100 grams of Cortex schizophragmatis integrifolii radicis, 100 grams of Herba speranskiae tuberculataes, 150 grams of Formica fuscas, 100 grams of Fructus Psoraleaes, 100 grams of Radix Ophiopogonis, 100 grams of Radix Rehmanniae, 100 grams of the Rhizoma Atractylodis Macrocephalaes, 150 grams, Poria, 100 grams of the Radix Paeoniae Albas, 100 grams of Radix Bupleuri, 150 grams, Radix Glycyrrhizae, 100 grams of Fructus Crataegis, 100 grams of Endothelium Corneum Gigeriae Galli, 50 grams of Fructus Broussonetiaes, 30 grams of RADIX PEUCEDANI, 60 grams of Herba Thlaspiss, 50 grams of Rhizoma Smilacis Chinensiss, 70 grams of Herba Cichoriis, 40 grams of Rhizoma Dioscoreae Septemlobaes, 60 grams of Herba Siegesbeckiaes, 30 grams of Herba Gendarussaes, 50 grams of Cortex Syingae Amurensiss, 30 grams of Herba pterocephali, 30 grams of Nodus Nelumbinis Rhizomatis, 70 grams of Medulla Stachyuri (Medulla Helwingiae)s, 40 grams of Flos Bombacis Malabaricis, 50 grams of Concha Arcaes, 30 grams of Caulis Mahoniaes, 60 grams of Folium Sauropis, 70 grams of Semen Lablab Albums, 30 grams of Retinervus Luffae Fructuss, 50 grams of Herba Polygoni cymosis, 50 grams of 30 grams of Semen Celosiae and Fructus Litseae, add 15000 ml waters, heats 6 hours at 80 DEG C.Filter, it is 1.06 (60 DEG C) that filtrate is concentrated into density, is cooled to room temperature, dry.Pulverize, add 250 grams, 290 grams of microcrystalline Cellulose, 170 grams of lactose and mannitol, mix homogeneously, crosses 80 mesh sieves.Then, make soft material in spray water, cross 20 mesh sieves to granulate, dry, granulate, packs in 100 seed lac softgel shells and obtains capsule of the present invention.
Experimental example
The equal out-patient treatment of 87 routine patient, wherein male's 23 examples, women's 64 examples; 20-40 year 18 examples; 41-50 year 24 examples; 51-60 year 38 examples, 60 years old above 7 example.46 years old mean age; The course of disease average April to 10 year; Sick kind: anemofrigid-damp arthralgia 22 examples, rheumatoid arthritis 12 examples, ankylosing spondylitis 6 examples, neck, shoulder, waist and leg arthralgia pain 47 examples; Differentiation of symptoms and signs for classification of syndrome: cold dampness accumulation pattern 33 examples, Qi deficiency blood stasis type 45 examples, phlegm-damp resistance network type 9 examples.Patient is divided into two groups, first group of 44 routine patient, second group of 43 routine patient, two groups are compared there was no significant difference (P > 0.05) in sides such as sex, age, the course of disease, state of an illness scorings, have comparability.
First group of capsule prepared by the oral embodiment 1 of patient, every day three times, each 2, treating 7 days is 1 course for the treatment of.
Second group of capsule prepared by the oral embodiment 2 of patient, every day three times, each 2, treating 7 days is 1 course for the treatment of.
Criterion of therapeutical effect
The criterion of therapeutical effect that the guideline of clinical investigations of the arthromyodynia of issuing with reference to Ministry of Public Health and Chinese combination of Chinese and Western medicine rheumatism Professional Committee formulate is also drafted in conjunction with clinical.Cure: disappear or substantially disappear through treating clinical symptomatology and sign, it is only normal that functional activity recovers, and main physical and chemical index normally or significantly declines; Effective: cardinal symptom is eliminated substantially, main function of joint is substantially recovered or is obviously progressive, can't take care of oneself and becomes and can take care of oneself, and main physical and chemical index makes moderate progress; Invalid: treatment is compared with before treatment, and clinical symptoms and sign etc. is all not improved.
Therapeutic outcome
In first group of patient, cure 24 examples, effective 20 examples; In second group of patient, cure 37 examples, effective 6 examples.
Claims (2)
1. a treatment rheumatism, the medicament of rheumatoid and waist lower limb arthralgia pain, it is characterized in that it is made up of the material of following weight proportioning: Radix Ginseng 10-15 part, Cornu Cervi Pantotrichum 2-4 part, Folium Ginkgo 10-15 part, Ganoderma 10-20 part, Placenta Hominis 30-50 part, Rhizoma Et Radix Notopterygii 10-20 part, Radix Angelicae Pubescentis 10-20 part, Herba Taxilli 10-30 part, Cortex Eucommiae 5-20 part, Radix Dipsaci 5-20 part, Rhizoma Cibotii 5-20 part, Radix Gentianae Macrophyllae 10-20 part, Radix Achyranthis Bidentatae 5-20 part, Fructus Chaenomelis 5-20 part, Radix Saposhnikoviae 5-20 part, Radix Paeoniae Rubra 10-20 part, Radix Angelicae Sinensis 5-20 part, Rhizoma Chuanxiong 5-20 part, Radix Notoginseng 1-5 part, Agkistrodon 200-300 part, Rhizoma Gastrodiae 5-20 part, Semen Strychni 1-5 part, Stigma Croci 1-5 part, Os Draconis 20-30 part, Concha Ostreae 20-30 part, Hirudo 30-40 part, Rhizoma Homalomenae 5-20 part, Cortex schizophragmatis integrifolii radicis 5-20 part, Herba speranskiae tuberculatae 5-20 part, Formica fusca 10-20 part, Fructus Psoraleae 1-15 part, Radix Ophiopogonis 10-15 part, Radix Rehmanniae 5-20 part, Rhizoma Atractylodis Macrocephalae 5-20 part, Poria 10-20 part, Radix Paeoniae Alba 5-20 part, Radix Bupleuri 5-20 part, Radix Glycyrrhizae 10-20 part, Fructus Crataegi 5-20 part and Endothelium Corneum Gigeriae Galli 5-20 part.
2. treatment rheumatism according to claim 1, the medicament of rheumatoid and waist lower limb arthralgia pain, it is characterized in that it is made up of the material of following weight proportioning: 10 parts of Radix Ginsengs, 3 parts, Cornu Cervi Pantotrichum, 15 parts of Folium Ginkgos, 15 parts of Ganodermas, 40 parts of Placenta Hominiss, 15 parts of Rhizoma Et Radix Notopterygiis, 15 parts of Radix Angelicae Pubescentiss, 20 parts of Herba Taxillis, 10 parts of the Cortexs Eucommiae, 10 parts of Radix Dipsacis, 10 parts of Rhizoma Cibotii, 15 parts of Radix Gentianae Macrophyllae, 10 parts of Radix Achyranthis Bidentataes, 10 parts of Fructus Chaenomeliss, 10 parts of Radix Saposhnikoviaes, 15 parts of Radix Paeoniae Rubra, 10 parts of Radix Angelicae Sinensis, 10 parts of Rhizoma Chuanxiongs, 3 parts of Radix Notoginseng, 250 parts of Agkistrodons, 10 parts, Rhizoma Gastrodiae, 3 parts of Semen Strychni, 3 parts of Stigma Crocis, 25 parts of Os Draconis, 25 parts of Concha Ostreaes, 35 parts of Hirudos, 10 parts of Rhizoma Homalomenaes, 10 parts of Cortex schizophragmatis integrifolii radicis, 10 parts of Herba speranskiae tuberculataes, 15 parts of Formica fuscas, 10 parts of Fructus Psoraleaes, 10 parts of Radix Ophiopogonis, 10 parts of Radix Rehmanniae, 10 parts of the Rhizoma Atractylodis Macrocephalaes, 15 parts, Poria, 10 parts of the Radix Paeoniae Albas, 10 parts of Radix Bupleuri, 15 parts, Radix Glycyrrhizae, 10 parts of 10 parts of Fructus Crataegis and Endothelium Corneum Gigeriae Galli.
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| CN103585536B (en) * | 2013-12-04 | 2015-05-13 | 刘奕平 | Preparation method of medicine for treating puerperal arthralgia |
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| CN103877335A (en) * | 2014-04-19 | 2014-06-25 | 王琴华 | Medicine for curing rheumatoid arthritis and preparation method of medicine |
| CN104056041A (en) * | 2014-07-03 | 2014-09-24 | 朱长怀 | Chinese herb preparation for treating sprains |
| CN105726646A (en) * | 2016-03-08 | 2016-07-06 | 青岛市中心医院 | Medicine composition for treating rheumatoid arthritis through immune adjustment and preparation method of medicine composition |
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| CN1144688A (en) * | 1996-07-13 | 1997-03-12 | 臧运升 | Medicine for treatment of lumbus and leg paralyses pain |
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| CN1144688A (en) * | 1996-07-13 | 1997-03-12 | 臧运升 | Medicine for treatment of lumbus and leg paralyses pain |
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| 中药治疗风湿伤痛的研究进展;李敏;《浙江中西医结合杂志》;20051231;第15卷(第4期);第262－264页 * |
| 李敏.中药治疗风湿伤痛的研究进展.《浙江中西医结合杂志》.2005,第15卷(第4期), |
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| CN103585536B (en) * | 2013-12-04 | 2015-05-13 | 刘奕平 | Preparation method of medicine for treating puerperal arthralgia |
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