CN103301202B - Chinese herbal medicine formula for assisting hypoglycemic - Google Patents
Chinese herbal medicine formula for assisting hypoglycemic Download PDFInfo
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- CN103301202B CN103301202B CN201310267580.6A CN201310267580A CN103301202B CN 103301202 B CN103301202 B CN 103301202B CN 201310267580 A CN201310267580 A CN 201310267580A CN 103301202 B CN103301202 B CN 103301202B
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Abstract
The invention discloses a Chinese herbal medicine formula for assisting hypoglycemic. The Chinese herbal medicine formula includes 3-8 parts of gynura medica, 9-17 parts of folium mori, and 3-8 parts of root of kudzu vine. The preferable components of the formula are 5 parts of gynura medica, 14 parts of folium mori, and 5 parts of root of kudzu vine. The Chinese herbal medicine formula has the function of assisting hypoglycemic.
Description
Technical field
The present invention relates to Chinese herbal medicine, particularly the Chinese herbal medicine of assistant hypoglycemic.
Background technology
Along with improving constantly of people's living standard, the unreasonable generation causing various disease of diet, as onset diabetes rate rises to some extent, in teenager, middle age, old age overweight people there is no lack of such people, diabetes are that a complication is many, can involve the endocrine metabolism disease of multisystem, multi viscera.In order to effectively improve clinical symptoms, make glycemic control in ideal scope, to alleviate, to delay and even to prevent the generation of complication.So the control of blood glucose is particularly important.
Summary of the invention
According to an aspect of the present invention, provide a kind of Chinese herb compound for assistant hypoglycemic, comprise Gynura Medica parts by weight 3 ~ 8 parts, Folium Mori parts by weight 9 ~ 17 parts, Radix Puerariae parts by weight 3 ~ 8 parts.
Gynura Medica Latin literary fame (GynuramedicaY.K.YangetJ.K.Wusp.nov.), medical material Ji Yuan is the herb of feverfew Gynura Medica, minimum, the oral safety of Gynura Medica toxicity, the similar biguanides of its blood sugar lowering mechanism.
Folium Mori are dried leaves of moraceae plants Mulberry, have another name called a Mulberry, Jing Sang, Fructus Mori tree, yellow wood etc.The effects such as dispelling wind and heat pathogens, clearing away lung-heat and moistening for dryness, suppressing the hyperactive liver improving eyesight, cooling blood for hemostasis.Be potent alpha-glucosidase inhibitor containing 1-DNJ, absorb and be better than acarbose; Suppress the conversion of human body sugar, the rising reducing fasting glucose and post-prandial glycemia is better than sulfonylurea drugs, and the probability that hypoglycemia and other side effect occur is significantly less than other hypoglycemic drug, and safety is good.
Radix Puerariae is legume pueraria lobata, and its sweet in the mouth is cool.Radix Puerariae Containing Carbohydrate, vegetable protein, multivitamin and mineral, in addition containing Flavonoid substances: Dai, daidzin, also have Dai-4,7-diglucoside, puerarin, puerarin-7-xyloside, Radix Puerariae alcohol, Radix Puerariae rattan and daidzin etc.
There is after having selected these Chinese herbal medicine to combine the effect of good blood sugar lowering.
The preferred formulation components of a kind of Chinese herb compound for assistant hypoglycemic is Gynura Medica parts by weight 5 parts, Folium Mori parts by weight 14 parts, Radix Puerariae parts by weight 5 parts.
The present invention's Gynura Medica used gets Gynura Medica water decoction extract, and Folium Mori get Folium Mori ethanol extraction, and Radix Puerariae gets Radix Puerariae ethanol extraction.Concentrate formulation uses less amount to achieve the goal.
Gynura Medica gets Gynura Medica water decoction extract extracting method: Gynura Medica smashs the water adding 5 times of weight to pieces, fried three times, merges three decocting liquid filtering residue final vacuums and is concentrated into constant weight.
Described Folium Mori get ethanol extraction extracting method: Folium Mori pulverized 40 mesh sieves, and reflux under adding 65% ethanol of 8 times of quality 2h, and filtering residue final vacuum is concentrated into constant weight.
Described Radix Puerariae gets ethanol extraction extracting method: Radix Puerariae smashs the 95% alcohol reflux 2h adding 8 times of quality to pieces, and filtering residue final vacuum is concentrated into constant weight.
Use concentrated extract can reduce patient's use amount instant edible and be convenient to the absorption of effective ingredient.
The present invention can be made into dissolved granule, oral liquid or capsule.
Detailed description of the invention
The present invention is below described in further detail.
Prepared by embodiment 1 herb type preparation
1, get dry Gynura Medica herb 300g, dry Folium Mori 900g, Radix puerariae root 300g pulverizing (< 100 order) mixes to obtain preparation A.
2, get dry Gynura Medica herb 500g, dry Folium Mori 1400g, Radix puerariae root 500g pulverizing (< 100 order) mixes to obtain preparation B.
3, get dry Gynura Medica herb 800g, dry Folium Mori 1700g, Radix puerariae root 800g pulverizing (< 100 order) mixes to obtain formulation C.
Prepared by embodiment 2 concentrated type preparation
Step 1
Gynura Medica gets Gynura Medica water decoction extract extracting method: get dry Gynura Medica and smash the water adding 5 times of weight to pieces, fried three times of little fire, merges three decocting liquid filtering residue final vacuums and is concentrated into constant weight.
Get Folium Mori and get ethanol extraction extracting method: get Folium Mori and pulverized 40 mesh sieves, reflux under adding 65% ethanol of 8 times of quality 2h, and filtering residue final vacuum is concentrated into constant weight.
Radix Puerariae gets ethanol extraction extracting method: Radix Puerariae smashs the 95% alcohol reflux 2h adding 8 times of quality to pieces, and filtering residue final vacuum is concentrated into constant weight.
Step 2
Get that step 1 obtains Gynura Medica extract 30g, Folium Mori extract 90g, Radix Puerariae extract 30g mixes to obtain preparation D.
Get that step 1 obtains Gynura Medica extract 50g, Folium Mori extract 140g, Radix Puerariae extract 50g mixes to obtain preparation E.
Get that step 1 obtains Gynura Medica extract 80g, Folium Mori extract 170g, Radix Puerariae extract 80g mixes to obtain preparation F.
Effect experimental
Health-care effect of the present invention is tested mainly through the trial test of people, is verified according to the real reaction effect of the similar comparative control of embodiment prescription long-term drink.Taste experiment through 120 people, the age, at 25 ~ 70 years old, 50.8 years old mean age, two months courses for the treatment of, eats, twice on the one after meal.Effective standard is: use product of the present invention fasting glucose≤7.0mmol/l course for the treatment of, or blood glucose comparatively test before decline 15%; Effective standard is: after using a course for the treatment of of product of the present invention, fasting glucose≤8.3mmol/l, or blood glucose comparatively test before decline 5%; Invalid standard is: after using a course for the treatment of of product of the present invention blood glucose comparatively test before without obviously reducing.
Efficacy result sees the following form:
Illustrate: taken embodiment 1 and the obtained preparation of embodiment 2 in experiment, all can reach hypoglycemic effect, by contrast, embodiment 2 best results.
The present invention is made sugar-free oral liquid, dissolved granule and capsule by the acceptable method of pharmacy.
Above-described is only some embodiments of the present invention.For the person of ordinary skill of the art, without departing from the concept of the premise of the invention, can also make some distortion and improvement, these all belong to the protection domain of invention.
Claims (2)
1. for a Chinese herb compound for assistant hypoglycemic, it is characterized in that, be made up of Gynura Medica water decoction extract, Folium Mori ethanol extraction and Radix Puerariae ethanol extraction;
Each component is processed as follows:
The mixing of Gynura Medica water decoction extract, Folium Mori ethanol extraction and Radix Puerariae ethanol extraction is obtained preparation; Described Gynura Medica water decoction extract, Folium Mori ethanol extraction and Radix Puerariae ethanol extraction, the extraction raw material weight number that these three kinds of extracts use is than being Gynura Medica 3 ~ 8 parts; 9 ~ 17 parts, Folium Mori; Radix Puerariae 3 ~ 8 parts;
The preparation method of described Gynura Medica water decoction extract is: Gynura Medica smashs the water adding 5 times of weight to pieces, fried three times, merges three decocting liquid filtering residue final vacuums and is concentrated into constant weight;
The preparation method of described Folium Mori ethanol extraction is: Folium Mori pulverized 40 mesh sieves, and reflux under adding 65% ethanol of 8 times of quality 2h, and filtering residue final vacuum is concentrated into constant weight;
The preparation method of described Radix Puerariae ethanol extraction is: Radix Puerariae smashs the 95% alcohol reflux 2h adding 8 times of quality to pieces, and filtering residue final vacuum is concentrated into constant weight.
2. a kind of Chinese herb compound for assistant hypoglycemic according to claim 1, is characterized in that, the extraction raw material weight number that described three kinds of extracts use is than being Gynura Medica parts by weight 5 parts; Folium Mori parts by weight 14 parts; Radix Puerariae parts by weight 5 parts.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201310267580.6A CN103301202B (en) | 2013-06-28 | 2013-06-28 | Chinese herbal medicine formula for assisting hypoglycemic |
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| CN201310267580.6A CN103301202B (en) | 2013-06-28 | 2013-06-28 | Chinese herbal medicine formula for assisting hypoglycemic |
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| CN103301202A CN103301202A (en) | 2013-09-18 |
| CN103301202B true CN103301202B (en) | 2015-06-03 |
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| CN201310267580.6A Active CN103301202B (en) | 2013-06-28 | 2013-06-28 | Chinese herbal medicine formula for assisting hypoglycemic |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN112603941A (en) * | 2021-01-13 | 2021-04-06 | 湘潭市中心医院 | Preparation method of traditional Chinese medicine extract for regulating glycolipid metabolism |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1602921A (en) * | 2004-08-04 | 2005-04-06 | 刘龙庚 | Medicine for treating diabetes and its preparing process |
| CN103156108A (en) * | 2013-04-02 | 2013-06-19 | 曾晓飞 | Fortified food for preventing and treating diabetes mellitus and hypertension diseases |
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2013
- 2013-06-28 CN CN201310267580.6A patent/CN103301202B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1602921A (en) * | 2004-08-04 | 2005-04-06 | 刘龙庚 | Medicine for treating diabetes and its preparing process |
| CN103156108A (en) * | 2013-04-02 | 2013-06-19 | 曾晓飞 | Fortified food for preventing and treating diabetes mellitus and hypertension diseases |
Non-Patent Citations (3)
| Title |
|---|
| 增敏降糖汤治疗2型糖尿病胰岛素抵抗36例;靳光荣;《陕西中医》;20101231;第31卷(第06期);第683-684页 * |
| 灵菊七的急性毒性与降糖作用研究;刘莹等;《解放军药学学报》;20051231;第21卷(第05期);第340-342页 * |
| 降血糖中药的有效成分与作用机制研究进展;张曼等;《广东药学院学报》;20111231;第27卷(第03期);第320-323页 * |
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