CN103272091A - Traditional Chinese medicinal oral preparation for treating chicken coccidiosis and preparation method thereof - Google Patents
Traditional Chinese medicinal oral preparation for treating chicken coccidiosis and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicinal oral preparation for treating chicken coccidiosis. The traditional Chinese medicinal oral preparation consists of the following traditional Chinese medicinal raw materials in parts by weight: 1-3 parts of radix dichroae, 1-3 parts of areca catechu, 1-3 parts of Chinese pulsatilla root, 1-2 parts of Szechwan chinaberry fruit, 1-3 parts of bupleurum chinense, 1-3 parts of cortex phellodendri chinensis, 1-3 parts of radix astragali and 1-2 parts of root of pilose asiabell. The traditional Chinese medicinal oral preparation is safe and reliable and overcomes the limitation of chemical medicines. The traditional Chinese medicinal oral preparation can be taken with water, is orally taken to be quickly absorbed, and has the characteristics of obvious and exact curative effect, no medicine residue and no toxic and side effects.
Description
Technical field
The present invention relates to the veterinary drug technical field, particularly relate to a kind of oral preparation of Chinese traditional medicinal for the treatment of chicken coccidiosis and preparation method thereof.
Background technology
Chicken coccidiosis is common in the modern intensive poultry, multiple, the great Enterozoa protozoacide of hazardness, and sickness rate is 50%~70%, mortality rate has caused greatly economic loss more than 80% to aquaculture.The chickling of recovering often is difficult for getting well in the several months, and becoming chicken is the carrier mostly, and growth and egg laying performance are all had a significant impact.But other poultry such as duck, turkey, Columba livia, Carnis Coturnicis japonicae etc. are infection morbidity all.Seriously threatening the development of China's poultry husbandry.The control chicken coccidiosis is researched and developed a kind of newtype drug and is made it reach both evident in efficacy, economical and practical at present, is difficult for producing drug resistance again, food safety and sanitation, and the purpose harmless to health is extremely urgent.
The medicine of producing anticoccidial at present has kind more than 20, roughly is divided into two classes, and the first kind is ion carrier antibiotic, as sulfa drugs, Maduramicin, Salinomycin etc.; Second class is chemical synthetic drug, as Robenidine, diclazuril etc.; Coccidiosis is easy to generate drug resistance to said medicine, and produces drug residue.
Summary of the invention
The objective of the invention is at the technological deficiency that exists in the prior art, and a kind of oral preparation of Chinese traditional medicinal of chicken coccidiosis and preparation method thereof of can effectively treating is provided, this oral formulations curative effect is outstanding, and no drug residue, problem has no side effect, has no drug resistance.
For realizing that the technical scheme that purpose of the present invention adopts is: a kind of oral preparation of Chinese traditional medicinal for the treatment of chicken coccidiosis, it is characterized in that: formed by following traditional Chinese medicine raw, count by weight: 1~3 part of Radix Dichroae, 1~3 part of Semen Arecae, 1~3 part of the Radix Pulsatillae, 1~2 part of Fructus Toosendan, 1~3 part of Radix Bupleuri, 1~3 part of Cortex Phellodendri, 1~3 part of the Radix Astragali, 1~2 part of Radix Codonopsis.
Preferably, the composition of above-mentioned raw material of Chinese medicine is according to the parts by weight meter: 3 parts of mattress Radix Dichroaes, 3 parts of Semen Arecaes, 2 parts of the Radix Pulsatillaes, 2 parts of Fructus Toosendans, 1 part of Radix Bupleuri, 1 part of Cortex Phellodendri, 1 part of the Radix Astragali, 1 part of Radix Codonopsis.
The preparation method of the oral preparation of Chinese traditional medicinal of above-mentioned treatment chicken coccidiosis is characterized in that carrying out as follows:
(1) takes by weighing 1~3 part of Radix Dichroae, 1~3 part of Semen Arecae, 1~3 part of the Radix Pulsatillae, 1~2 part of Fructus Toosendan, 1~3 part of Radix Bupleuri, 1~3 part of Cortex Phellodendri, 1~3 part of the Radix Astragali, 1~2 part of Radix Codonopsis;
(2) raw material of Chinese medicine that step (1) taken by weighing adds the water of 10 times of amounts, decocts 2 times, and each 2 hours, collecting decoction, with the filtration of 80 silks, filtrate was left standstill 24 hours, and getting supernatant, to be concentrated into relative density under 65 ℃ of conditions be 1.2~1.3 thick paste;
(3) concentrate in step (2) and add the sucrose that weight is the raw material of Chinese medicine gross weight 70% that takes by weighing of step (1) in the thick paste make, mixing is crossed the 20-60 mesh sieve, makes granule, drying, and packing, namely.
Preferably, the raw material of Chinese medicine that takes by weighing in the above-mentioned steps (1) is according to the parts by weight meter: 3 parts of mattress Radix Dichroaes, 3 parts of Semen Arecaes, 2 parts of the Radix Pulsatillaes, 2 parts of Fructus Toosendans, 1 part of Radix Bupleuri, 1 part of Cortex Phellodendri, 1 part of the Radix Astragali, 1 part of Radix Codonopsis.
Above-mentioned relative density refers to the proportion of this supernatant.
Compared with prior art, the invention has the beneficial effects as follows: a kind of oral preparation of Chinese traditional medicinal that can effectively treat chicken coccidiosis is provided, safe and reliable, overcome the limitation of chemicals, this product can be drunk water and be taken, the for oral administration absorption rapidly has evident in efficacy, certain, no drug residue, characteristics without any side effects.
The specific embodiment
Below in conjunction with specific embodiment the present invention is described in further detail.Should be appreciated that specific embodiment described herein only in order to explaining the present invention, and be not used in restriction the present invention.
Embodiment 1:
A kind of oral preparation of Chinese traditional medicinal for the treatment of chicken coccidiosis is made up of following medicine, and every part by 50g: 3 parts of Radix Dichroaes, 3 parts of Semen Arecaes, 2 parts of the Radix Pulsatillaes, 2 parts of Fructus Toosendans, 1 part of Radix Bupleuri, 1 part of Cortex Phellodendri, 1 part of the Radix Astragali, 1 part of Radix Codonopsis.
A kind of preparation method for the treatment of the oral preparation of Chinese traditional medicinal of chicken coccidiosis, carry out as follows:
(1) takes by weighing 3 parts of Radix Dichroaes, 3 parts of Semen Arecaes, 2 parts of the Radix Pulsatillaes, 2 parts of Fructus Toosendans, 1 part of Radix Bupleuri, 1 part of Cortex Phellodendri, 1 part of the Radix Astragali, 1 part of Radix Codonopsis;
(2) raw material of Chinese medicine that step (1) taken by weighing adds the water of 10 times of amounts, decocts 2 times, and each 2 hours, collecting decoction, with the filtration of 80 silks, filtrate was left standstill 24 hours, and getting supernatant, to be concentrated into relative density under 65 ℃ of conditions be 1.2~1.3 thick paste;
(3) concentrate in step (2) and add the sucrose that weight is the raw material of Chinese medicine gross weight 70% that takes by weighing of step (1) in the thick paste make, mixing is crossed 40 mesh sieves, makes granule, drying, and packing, namely.
Embodiment 2:
A kind of oral preparation of Chinese traditional medicinal for the treatment of chicken coccidiosis is made up of following medicine, and every part by 50g: 1 part of Radix Dichroae, 3 parts of Semen Arecaes, 2 parts of the Radix Pulsatillaes, 1 part of Fructus Toosendan, 2 parts of Radix Bupleuri, 3 parts of Cortex Phellodendris, 1 part of the Radix Astragali, 2 parts of Radix Codonopsis.
A kind of preparation method for the treatment of the oral preparation of Chinese traditional medicinal of chicken coccidiosis, carry out as follows:
(1) takes by weighing 1 part of Radix Dichroae, 3 parts of Semen Arecaes, 2 parts of the Radix Pulsatillaes, 1 part of Fructus Toosendan, 2 parts of Radix Bupleuri, 3 parts of Cortex Phellodendris, 1 part of the Radix Astragali, 2 parts of Radix Codonopsis;
(2) raw material of Chinese medicine that step (1) taken by weighing adds the water of 10 times of amounts, decocts 2 times, and each 2 hours, collecting decoction, with the filtration of 80 silks, filtrate was left standstill 24 hours, and getting supernatant, to be concentrated into relative density under 65 ℃ of conditions be 1.2~1.3 thick paste;
(3) concentrate in step (2) and add the sucrose that weight is the raw material of Chinese medicine gross weight 70% that takes by weighing of step (1) in the thick paste make, mixing is crossed 20 mesh sieves, makes granule, drying, and packing, namely.
Embodiment 3:
A kind of oral preparation of Chinese traditional medicinal for the treatment of chicken coccidiosis is made up of following medicine, and every part by 50g: 2 parts of Radix Dichroaes, 1 part of Semen Arecae, 3 parts of the Radix Pulsatillaes, 1 part of Fructus Toosendan, 3 parts of Radix Bupleuri, 1 part of Cortex Phellodendri, 2 parts of the Radixs Astragali, 2 parts of Radix Codonopsis.
A kind of preparation method for the treatment of the oral preparation of Chinese traditional medicinal of chicken coccidiosis, carry out as follows:
(1) takes by weighing 2 parts of Radix Dichroaes, 1 part of Semen Arecae, 3 parts of the Radix Pulsatillaes, 1 part of Fructus Toosendan, 3 parts of Radix Bupleuri, 1 part of Cortex Phellodendri, 2 parts of the Radixs Astragali, 2 parts of Radix Codonopsis;
(2) raw material of Chinese medicine that step (1) taken by weighing adds the water of 10 times of amounts, decocts 2 times, and each 2 hours, collecting decoction, with the filtration of 80 silks, filtrate was left standstill 24 hours, and getting supernatant, to be concentrated into relative density under 65 ℃ of conditions be 1.2~1.3 thick paste;
(3) concentrate in step (2) and add the sucrose that weight is the raw material of Chinese medicine gross weight 70% that takes by weighing of step (1) in the thick paste make, mixing is crossed 60 mesh sieves, makes granule, drying, and packing, namely.
Embodiment 4:
A kind of oral preparation of Chinese traditional medicinal for the treatment of chicken coccidiosis is made up of following medicine, presses 50g meter: 3 parts of Radix Dichroaes, 2 parts of Semen Arecaes, 1 part of the Radix Pulsatillae, 2 parts of Fructus Toosendans, 2 parts of Radix Bupleuri, 2 parts of Cortex Phellodendris, 3 parts of the Radixs Astragali, 1 part of Radix Codonopsis for every part.
A kind of preparation method for the treatment of the oral preparation of Chinese traditional medicinal of chicken coccidiosis, carry out as follows:
(1) takes by weighing 3 parts of Radix Dichroaes, 2 parts of Semen Arecaes, 1 part of the Radix Pulsatillae, 2 parts of Fructus Toosendans, 2 parts of Radix Bupleuri, 2 parts of Cortex Phellodendris, 3 parts of the Radixs Astragali, 1 part of Radix Codonopsis;
(2) raw material of Chinese medicine that step (1) taken by weighing adds the water of 10 times of amounts, decocts 2 times, and each 2 hours, collecting decoction, with the filtration of 80 silks, filtrate was left standstill 24 hours, and getting supernatant, to be concentrated into relative density under 65 ℃ of conditions be 1.2~1.3 thick paste;
(3) concentrate in step (2) and add the sucrose that weight is the raw material of Chinese medicine gross weight 70% that takes by weighing of step (1) in the thick paste make, mixing is crossed 40 mesh sieves, makes granule, drying, and packing, namely.
The described Chinese crude drug of one of embodiment 1-4 is the commercially available prod, and each amounts of components is increased or reduces according to same ratio, and the parts by weight relation of each component of gained all belongs to protection scope of the present invention.
The described Chinese crude drug of embodiment 1-4 all meets " Chinese veterinary drug allusion quotation " version two ministerial standards in 2010.
Composition principle of the present invention is: Radix Dichroae parasite killing, expectorant removing food stagnancy; The Semen Arecae anthelmintic, removing food stagnancy, the capable water of sending down the abnormal ascending QI; Radix Pulsatillae heat-clearing and toxic substances removing, eliminating pathogenic heat from blood to cure dysentery; Herba Agrimoniae: relieve internal heat, cooling blood for hemostasis, the detumescent of healing the wounds; Fructus Toosendan: soothing liver-QI, promoting the circulation of QI to relieve pain, anthelmintic; The Radix Astragali: tonifying Qi and lifting yang, inducing diuresis to remove edema, holder skin ulcer life, strong immunity of organisms once; The Radix Bupleuri invigorating the spleen and replenishing QI, the spleen invigorating lung benefiting; The Cortex Phellodendri heat clearing and damp drying, eliminating fire and detoxication, reducing the asthenic fever; The Radix Codonopsis invigorating the spleen and replenishing QI, the spleen invigorating lung benefiting; All medicines share, and play anthelmintic, eliminating pathogenic heat from blood to cure dysentery soothing liver-QI altogether, promoting the circulation of QI to relieve pain, detoxifcation, enhancing human body immunity power.
Clinical trial:
On May 10th, 2012, the chicken morbidity of 5000 20 ages in days that Shandong Heze City poultry specialist raises, clinical symptoms: sick chicken spirit is depressed, and feather is fluffy, head is crispaturaed, loss of appetite is full of liquid in the crop, cockscomb and visual mucosa anemia, pale, become thin gradually, sick chicken is often arranged red calabash Radix Raphani sample feces, is with blood in the feces, and contains the intestinal mucosa that comes off in a large number.And 15 death are arranged.Be diagnosed as chicken coccidiosis.The oral preparation of Chinese traditional medicinal of the embodiment of the invention 1 preparation is added water the 200kg mixing by 100g, in the drinking-water, allows chicken freely drink, be used in conjunction 3~5 days after, the state of an illness is controlled, occurs dead again.After one week, sick chicken transfers to normally, and showing as feed intake increases, and red calabash Radix Raphani sample feces occurring, is not with blood in the feces.Feather gloss, spirit is good.
The above only is preferred implementation of the present invention; should be pointed out that for those skilled in the art, under the prerequisite that does not break away from the principle of the invention; can also make some improvements and modifications, these improvements and modifications also should be considered as protection scope of the present invention.
Claims (4)
1. oral preparation of Chinese traditional medicinal for the treatment of chicken coccidiosis, it is characterized in that: formed by following traditional Chinese medicine raw, by weight meter: 1~3 part of Radix Dichroae, 1~3 part of Semen Arecae, 1~3 part of the Radix Pulsatillae, 1~2 part of Fructus Toosendan, 1~3 part of Radix Bupleuri, 1~3 part of Cortex Phellodendri, 1~3 part of the Radix Astragali, 1~2 part of Radix Codonopsis.
2. a kind of oral preparation of Chinese traditional medicinal for the treatment of chicken coccidiosis according to claim 1, it is characterized in that: the composition of described raw material of Chinese medicine is according to the parts by weight meter: 3 parts of mattress Radix Dichroaes, 3 parts of Semen Arecaes, 2 parts of the Radix Pulsatillaes, 2 parts of Fructus Toosendans, 1 part of Radix Bupleuri, 1 part of Cortex Phellodendri, 1 part of the Radix Astragali, 1 part of Radix Codonopsis.
3. the described a kind of preparation method for the treatment of the oral preparation of Chinese traditional medicinal of chicken coccidiosis of claim 1 is characterized in that carrying out as follows:
(1) takes by weighing 1~3 part of Radix Dichroae, 1~3 part of Semen Arecae, 1~3 part of the Radix Pulsatillae, 1~2 part of Fructus Toosendan, 1~3 part of Radix Bupleuri, 1~3 part of Cortex Phellodendri, 1~3 part of the Radix Astragali, 1~2 part of Radix Codonopsis;
(2) raw material of Chinese medicine that step (1) taken by weighing adds the water of 10 times of amounts, decocts 2 times, and each 2 hours, collecting decoction, with the filtration of 80 silks, filtrate was left standstill 24 hours, and getting supernatant, to be concentrated into relative density under 65 ℃ of conditions be 1.2~1.3 thick paste;
(3) concentrate in step (2) and add the sucrose that weight is the raw material of Chinese medicine gross weight 70% that takes by weighing of step (1) in the thick paste make, mixing is crossed the 20-60 mesh sieve, makes granule, drying, and packing, namely.
4. a kind of preparation method for the treatment of the oral preparation of Chinese traditional medicinal of chicken coccidiosis according to claim 3, it is characterized in that the raw material of Chinese medicine that takes by weighing in the described step (1) is according to the parts by weight meter: 3 parts of mattress Radix Dichroaes, 3 parts of Semen Arecaes, 2 parts of the Radix Pulsatillaes, 2 parts of Fructus Toosendans, 1 part of Radix Bupleuri, 1 part of Cortex Phellodendri, 1 part of the Radix Astragali, 1 part of Radix Codonopsis.
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CN103721147A (en) * | 2013-10-23 | 2014-04-16 | 青岛华仁技术孵化器有限公司 | Traditional Chinese medicine composition for treating chicken coccidiosis |
CN104666638A (en) * | 2013-11-28 | 2015-06-03 | 天津嘉瑞生物科技有限公司 | Traditional Chinese medicine composition for treating commercial broiler caecum coccidiosis and preparation method thereof |
CN107308235A (en) * | 2017-06-27 | 2017-11-03 | 齐全农牧集团股份有限公司 | A kind of Chinese medicine composition and preparation method for preventing and treating chicken coccidiasis |
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CN103721147A (en) * | 2013-10-23 | 2014-04-16 | 青岛华仁技术孵化器有限公司 | Traditional Chinese medicine composition for treating chicken coccidiosis |
CN103721147B (en) * | 2013-10-23 | 2016-08-17 | 杨高林 | For treating the Chinese medicine composition of chicken coccidiasis |
CN104666638A (en) * | 2013-11-28 | 2015-06-03 | 天津嘉瑞生物科技有限公司 | Traditional Chinese medicine composition for treating commercial broiler caecum coccidiosis and preparation method thereof |
CN108653541A (en) * | 2017-03-31 | 2018-10-16 | 天津市佳禾蛋鸡养殖有限公司 | Treat the chicken medication of globidiosis strengthen immunity |
CN107308235A (en) * | 2017-06-27 | 2017-11-03 | 齐全农牧集团股份有限公司 | A kind of Chinese medicine composition and preparation method for preventing and treating chicken coccidiasis |
CN112891474A (en) * | 2021-02-20 | 2021-06-04 | 中国人民解放军火箭军特色医学中心 | Prevention and treatment medicament for body surface parasites of plateau woodchucks |
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