CN103251528B - A kind of whitening and speckle dispelling Chinese medicine composition - Google Patents
A kind of whitening and speckle dispelling Chinese medicine composition Download PDFInfo
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- CN103251528B CN103251528B CN201310140349.0A CN201310140349A CN103251528B CN 103251528 B CN103251528 B CN 103251528B CN 201310140349 A CN201310140349 A CN 201310140349A CN 103251528 B CN103251528 B CN 103251528B
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- 239000000203 mixture Substances 0.000 title claims abstract description 28
- 239000003814 drug Substances 0.000 title claims abstract description 26
- 230000002087 whitening effect Effects 0.000 title claims abstract description 17
- 241000628997 Flos Species 0.000 claims abstract description 33
- 240000008669 Hedera helix Species 0.000 claims abstract description 11
- 244000207740 Lemna minor Species 0.000 claims abstract description 11
- 235000006439 Lemna minor Nutrition 0.000 claims abstract description 11
- 235000001855 Portulaca oleracea Nutrition 0.000 claims abstract description 11
- 241000209501 Spirodela Species 0.000 claims abstract description 11
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 claims abstract description 11
- 210000000582 semen Anatomy 0.000 claims abstract description 11
- GYDJEQRTZSCIOI-LJGSYFOKSA-N tranexamic acid Chemical compound NC[C@H]1CC[C@H](C(O)=O)CC1 GYDJEQRTZSCIOI-LJGSYFOKSA-N 0.000 claims abstract description 11
- 229960000401 tranexamic acid Drugs 0.000 claims abstract description 11
- 239000000706 filtrate Substances 0.000 claims description 9
- 239000000839 emulsion Substances 0.000 claims description 7
- 230000001476 alcoholic effect Effects 0.000 claims description 6
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 claims description 5
- 239000002253 acid Substances 0.000 claims description 5
- 239000011777 magnesium Substances 0.000 claims description 5
- 229910052749 magnesium Inorganic materials 0.000 claims description 5
- 238000002360 preparation method Methods 0.000 claims description 5
- 239000002671 adjuvant Substances 0.000 claims description 4
- 238000009472 formulation Methods 0.000 claims description 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 3
- 238000009834 vaporization Methods 0.000 claims description 3
- 230000008016 vaporization Effects 0.000 claims description 3
- 239000006071 cream Substances 0.000 claims description 2
- 230000001815 facial effect Effects 0.000 claims description 2
- 229940079593 drug Drugs 0.000 claims 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 abstract description 12
- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 abstract description 10
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 abstract description 6
- 229930003268 Vitamin C Natural products 0.000 abstract description 6
- 150000002148 esters Chemical class 0.000 abstract description 6
- 239000002994 raw material Substances 0.000 abstract description 6
- 235000019154 vitamin C Nutrition 0.000 abstract description 6
- 239000011718 vitamin C Substances 0.000 abstract description 6
- 230000017531 blood circulation Effects 0.000 abstract description 3
- 235000016709 nutrition Nutrition 0.000 abstract description 3
- 230000035764 nutrition Effects 0.000 abstract description 3
- 150000003254 radicals Chemical class 0.000 abstract description 3
- 108010082495 Dietary Plant Proteins Proteins 0.000 abstract description 2
- 239000011573 trace mineral Substances 0.000 abstract description 2
- 235000013619 trace mineral Nutrition 0.000 abstract description 2
- 208000003351 Melanosis Diseases 0.000 description 3
- 239000002537 cosmetic Substances 0.000 description 3
- 206010020751 Hypersensitivity Diseases 0.000 description 2
- 208000026935 allergic disease Diseases 0.000 description 2
- 230000007815 allergy Effects 0.000 description 2
- 239000008346 aqueous phase Substances 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 230000003203 everyday effect Effects 0.000 description 2
- 206010025482 malaise Diseases 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 description 1
- 206010008570 Chloasma Diseases 0.000 description 1
- 208000012641 Pigmentation disease Diseases 0.000 description 1
- 238000013019 agitation Methods 0.000 description 1
- 230000002421 anti-septic effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000019522 cellular metabolic process Effects 0.000 description 1
- 230000008451 emotion Effects 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000004006 olive oil Substances 0.000 description 1
- 235000008390 olive oil Nutrition 0.000 description 1
- 230000019612 pigmentation Effects 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 230000036559 skin health Effects 0.000 description 1
- 230000005808 skin problem Effects 0.000 description 1
- 235000010413 sodium alginate Nutrition 0.000 description 1
- 229940005550 sodium alginate Drugs 0.000 description 1
- 239000000661 sodium alginate Substances 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
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- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a kind of Chinese medicine composition of whitening and speckle dispelling, it contains the raw material of Chinese medicine of following mass parts: Radix Angelicae Sinensis 25 ~ 35 parts, Rhizoma Chuanxiong 20 ~ 30 parts, Semen Lablab Album 10 ~ 20 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 10 ~ 20 parts, the Rhizoma Atractylodis Macrocephalae 10 ~ 20 parts, the Radix Paeoniae Alba 10 ~ 20 parts, 15 ~ 25 parts, Flos Carthami, duckweed spirodela 8 ~ 12 parts, Retinervus Luffae Fructus 10 ~ 20 parts, 40 ~ 60 parts, Flos persicae, Flos Pruni 40 ~ 60 parts, vitamin C phosphoric ester U.S. 2 ~ 5 parts, tranexamic acid 2 parts.Whitening and speckle dispelling Chinese medicine composition of the present invention is formulated according to Chinese and western medical theory, be rich in the trace element of vegetable protein and various needed by human body, can skin nutrition, promote face blood circulation, eliminate the growth of free radical, check melanin, life-time service can make skin stay pale, and elasticity is moistened.
Description
Technical field
The invention belongs to cosmetic technical field, be specifically related to a kind of whitening and speckle dispelling Chinese medicine composition.
Background technology
Melanin is a kind of protein being present in everyone skin base layer; ultraviolet irradiation can make melanin change; generate a kind of material protecting skin; moving layer by layer again via cellular metabolism; arrive skin epidermal area, thus define the skin problems such as seen mottle, the colour of skin be irregular, dark yellow.
Female face pigmentation, tarnish, dark yellow etc. be the young and middle-aged women skin of face problem that especially this age working woman is the most common, affect emotion and the life of young and middle-aged women.Along with the development of science and technology, growth in the living standard and the raising to skin health consciousness, the attention rate of people to cosmetics is also more and more higher.Natural, green, safe and effective Chinese medicine cosmetic also more and more receives the concern of numerous people and likes.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine composition of whitening and speckle dispelling.
Technical scheme of the present invention is:
A Chinese medicine composition for whitening and speckle dispelling, the raw material of Chinese medicine containing following mass parts: Radix Angelicae Sinensis 25 ~ 35 parts, Rhizoma Chuanxiong 20 ~ 30 parts, Semen Lablab Album 10 ~ 20 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 10 ~ 20 parts, the Rhizoma Atractylodis Macrocephalae 10 ~ 20 parts, the Radix Paeoniae Alba 10 ~ 20 parts, 15 ~ 25 parts, Flos Carthami, duckweed spirodela 8 ~ 12 parts, Retinervus Luffae Fructus 10 ~ 20 parts, 40 ~ 60 parts, Flos persicae, Flos Pruni 40 ~ 60 parts, vitamin C phosphoric ester U.S. 2 ~ 5 parts, tranexamic acid 1 ~ 3 part.
Preferably, described Chinese medicine composition contains the raw material of Chinese medicine of following mass parts: Radix Angelicae Sinensis 30 parts, Rhizoma Chuanxiong 25 parts, Semen Lablab Album 15 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 15 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, the Radix Paeoniae Alba 15 parts, 20 parts, Flos Carthami, duckweed spirodela 10 parts, Retinervus Luffae Fructus 15 parts, 50 parts, Flos persicae, Flos Pruni 50 parts, vitamin C phosphoric ester U.S. 3 parts, tranexamic acid 1 part.
Also containing pharmaceutically acceptable adjuvant or carrier in described compositions.
A Chinese medicine composition for whitening and speckle dispelling, comprises the steps:
(1) take Radix Angelicae Sinensis, Rhizoma Chuanxiong, Semen Lablab Album, the Pseudobulbus Bletillae (Rhizoma Bletillae), the Rhizoma Atractylodis Macrocephalae, the Radix Paeoniae Alba by formula proportion, after Mechanical Crushing, add the alcoholic solution of 50 ~ 80% of 2 ~ 4 times of volumes, 50 ~ 80 DEG C are extracted 1 ~ 3 time, each 1 ~ 3 hour, filter, merging filtrate;
(2) take Flos Carthami, duckweed spirodela, Retinervus Luffae Fructus, Flos persicae, Flos Pruni by formula proportion, after Mechanical Crushing, add the alcoholic solution of 50 ~ 80% of 2 ~ 4 times of volumes, 35 ~ 45 DEG C are extracted 1 ~ 3 time, each 1 ~ 3 hour, filter, merging filtrate;
(3) filtrate of combining step (1) and step (2), reduction vaporization, to without alcohol taste, adds Magnesium L-Asacorbic Acid 2-O-Phosphate and the tranexamic acid of formula ratio, mix homogeneously, continues to add other adjuvants or carrier, make exterior-applied formulation.
Described exterior-applied formulation comprises emulsion, cream frost, facial film etc.
The invention has the beneficial effects as follows: whitening and speckle dispelling Chinese medicine composition of the present invention is formulated according to Chinese and western medical theory, be rich in the trace element of vegetable protein and various needed by human body, can skin nutrition, promote face blood circulation, eliminate the growth of free radical, check melanin, life-time service can make skin stay pale, and elasticity is moistened.
Detailed description of the invention
The present invention is explained further below in conjunction with embodiment.Should be understood that these embodiments are only not used in for illustration of the present invention to limit the scope of the invention.
Embodiment 1
A Chinese medicine composition for whitening and speckle dispelling, the raw material of Chinese medicine containing following mass parts: Radix Angelicae Sinensis 25 parts, Rhizoma Chuanxiong 20 parts, Semen Lablab Album 10 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 10 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, the Radix Paeoniae Alba 10 parts, 15 parts, Flos Carthami, duckweed spirodela 8 parts, Retinervus Luffae Fructus 10 parts, 40 parts, Flos persicae, Flos Pruni 40 parts, vitamin C phosphoric ester U.S. 2 parts, tranexamic acid 1 part.
Preparation method is as follows:
(1) take Radix Angelicae Sinensis, Rhizoma Chuanxiong, Semen Lablab Album, the Pseudobulbus Bletillae (Rhizoma Bletillae), the Rhizoma Atractylodis Macrocephalae, the Radix Paeoniae Alba by formula proportion, after Mechanical Crushing, add the alcoholic solution of 65% of 3 times of volumes, 60 DEG C are extracted 3 times, each 2 hours, filter, merging filtrate;
(2) take Flos Carthami, duckweed spirodela, Retinervus Luffae Fructus, Flos persicae, Flos Pruni by formula proportion, after Mechanical Crushing, add the alcoholic solution of 65% of 2 times of volumes, 40 DEG C are extracted 2 times, each 1 hour, filter, merging filtrate;
(3) filtrate of combining step (1) and step (2), reduction vaporization is extremely without alcohol taste, and add Magnesium L-Asacorbic Acid 2-O-Phosphate and the tranexamic acid of formula ratio, mix homogeneously, filtration sterilization, obtains aqueous phase;
(4) at 60 DEG C, in aqueous phase, slowly add the sodium alginate of 25 mass parts and the olive oil of 15 mass parts, Keep agitation makes it be mixed into emulsion form thing, adds appropriate essence and antiseptic, and namely adjust ph to 5.5 ~ 6.5 obtain whitening and speckle dispelling emulsion.
Embodiment 2
A Chinese medicine composition for whitening and speckle dispelling, the raw material of Chinese medicine containing following mass parts: Radix Angelicae Sinensis 30 parts, Rhizoma Chuanxiong 25 parts, Semen Lablab Album 15 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 15 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, the Radix Paeoniae Alba 15 parts, 20 parts, Flos Carthami, duckweed spirodela 10 parts, Retinervus Luffae Fructus 15 parts, 50 parts, Flos persicae, Flos Pruni 50 parts, vitamin C phosphoric ester U.S. 3 parts, tranexamic acid 1 part.
Preparation method is with embodiment 1.
Embodiment 3
A Chinese medicine composition for whitening and speckle dispelling, the raw material of Chinese medicine containing following mass parts: Radix Angelicae Sinensis 35 parts, Rhizoma Chuanxiong 30 parts, Semen Lablab Album 20 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 20 parts, the Rhizoma Atractylodis Macrocephalae 20 parts, the Radix Paeoniae Alba 20 parts, 25 parts, Flos Carthami, duckweed spirodela 12 parts, Retinervus Luffae Fructus 20 parts, 60 parts, Flos persicae, Flos Pruni 60 parts, vitamin C phosphoric ester U.S. 5 parts, tranexamic acid 3 parts.
Preparation method is with embodiment 1.
Result of use:
The female volunteers that case 1:25 name face chloasma is more serious, at 35 ~ 45 years old age, preliminary skin test, without after allergy, uses the whitening and speckle dispelling emulsion of the embodiment of the present invention 1 to embrocate face every day, and sooner or later respectively once, after adhering to 30 days, mottle color is thin out; Continue use after 60 days, face's mottle color of 25 volunteers is obviously thin out, and wherein the mottle fade of 18 examples is greater than 75%, and have rosy cheeks, turgor.7 routine mottles disappear about 50%.Whole volunteer is all without malaise symptoms.
Case 2:12 name face head has the female volunteers of freckle, 25 ~ 30 years old age, and preliminary skin test, without after allergy, uses the whitening and speckle dispelling emulsion of the embodiment of the present invention 2 to embrocate face every day, and sooner or later respectively once, after adhering to 30 days, mottle color is thin out; Continue use after 3 months, wherein face's mottle color of 9 volunteers is obviously thin out, and have rosy cheeks, smooth.But wherein the freckle of 3 volunteer faces disappears not obvious, intractable mottle may be belonged to.Whole volunteer is all without malaise symptoms.
Above case shows, whitening and speckle dispelling emulsion of the present invention can skin nutrition, promote face blood circulation, eliminate the growth of free radical, check melanin, life-time service can make skin stay pale, and elasticity is moistened.
Claims (5)
1. the Chinese medicine composition of a whitening and speckle dispelling, it is characterized in that, the crude drug of described compositions is made up of the component of following mass parts: Radix Angelicae Sinensis 25 ~ 35 parts, Rhizoma Chuanxiong 20 ~ 30 parts, Semen Lablab Album 10 ~ 20 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 10 ~ 20 parts, the Rhizoma Atractylodis Macrocephalae 10 ~ 20 parts, the Radix Paeoniae Alba 10 ~ 20 parts, 15 ~ 25 parts, Flos Carthami, duckweed spirodela 8 ~ 12 parts, Retinervus Luffae Fructus 10 ~ 20 parts, 40 ~ 60 parts, Flos persicae, Flos Pruni 40 ~ 60 parts, Magnesium L-Asacorbic Acid 2-O-Phosphate 2 ~ 5 parts, tranexamic acid 1 ~ 3 part.
2. Chinese medicine composition according to claim 1, it is characterized in that, the crude drug of described compositions is made up of the component of following mass parts: Radix Angelicae Sinensis 30 parts, Rhizoma Chuanxiong 25 parts, Semen Lablab Album 15 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 15 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, the Radix Paeoniae Alba 15 parts, 20 parts, Flos Carthami, duckweed spirodela 10 parts, Retinervus Luffae Fructus 15 parts, 50 parts, Flos persicae, Flos Pruni 50 parts, Magnesium L-Asacorbic Acid 2-O-Phosphate 3 parts, tranexamic acid 1 part.
3. Chinese medicine composition according to claim 1 and 2, is characterized in that, also containing pharmaceutically acceptable adjuvant or carrier in described compositions.
4. the preparation method of Chinese medicine composition described in claim 1 or 2, comprises the steps:
(1) take Radix Angelicae Sinensis, Rhizoma Chuanxiong, Semen Lablab Album, the Pseudobulbus Bletillae (Rhizoma Bletillae), the Rhizoma Atractylodis Macrocephalae, the Radix Paeoniae Alba by formula proportion, after Mechanical Crushing, add the alcoholic solution of 50 ~ 80% of 2 ~ 4 times of volumes, 50 ~ 80 DEG C are extracted 1 ~ 3 time, each 1 ~ 3 hour, filter, merging filtrate;
(2) take Flos Carthami, duckweed spirodela, Retinervus Luffae Fructus, Flos persicae, Flos Pruni by formula proportion, after Mechanical Crushing, add the alcoholic solution of 50 ~ 80% of 2 ~ 4 times of volumes, 35 ~ 45 DEG C are extracted 1 ~ 3 time, each 1 ~ 3 hour, filter, merging filtrate;
(3) filtrate of combining step (1) and step (2), reduction vaporization, to without alcohol taste, adds Magnesium L-Asacorbic Acid 2-O-Phosphate and the tranexamic acid of formula ratio, mix homogeneously, continues to add other adjuvants or carrier, make exterior-applied formulation.
5. preparation method according to claim 4, is characterized in that, described exterior-applied formulation comprises emulsion, cream frost, facial film.
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| CN201310140349.0A CN103251528B (en) | 2013-04-22 | 2013-04-22 | A kind of whitening and speckle dispelling Chinese medicine composition |
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| CN201310140349.0A CN103251528B (en) | 2013-04-22 | 2013-04-22 | A kind of whitening and speckle dispelling Chinese medicine composition |
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| CN103251528A CN103251528A (en) | 2013-08-21 |
| CN103251528B true CN103251528B (en) | 2015-09-02 |
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Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103540457A (en) * | 2013-10-18 | 2014-01-29 | 桂林雪芙莲日化有限公司 | Whitening and freckle-removing toilet soap |
| CN104586664B (en) * | 2013-10-31 | 2017-12-12 | 广州市纳爱生物科技有限公司 | A kind of whitening spot-removing emulsion |
| CN104434650B (en) * | 2014-11-18 | 2017-10-03 | 皖南医学院 | A kind of relax skin whitening, moisturizing of pressure of allaying excitement is energized emulsion and preparation method thereof |
| CN105232981A (en) * | 2015-10-28 | 2016-01-13 | 陆莎 | Chinese herbal medicine composition for treating under-eye dark circle, moisturizing skin and maintaining beauty |
| CN105998699A (en) * | 2016-06-30 | 2016-10-12 | 潜山县有余瓜蒌开发有限责任公司 | Whitening and freckle removing snake gourd fruit traditional Chinese medicinal composition and preparation process for same |
| CN106880563B (en) * | 2017-02-21 | 2018-07-20 | 广东药科大学 | A kind of Chinese medicine skin whitening, moisturizing gel frost and preparation method thereof |
| CN108310233A (en) * | 2018-04-04 | 2018-07-24 | 武汉名实生物医药科技有限责任公司 | A kind of pharmaceutical composition and preparation method thereof with spot-removing function |
| CN110393693A (en) * | 2019-08-27 | 2019-11-01 | 万红军 | The net skin beauty face-whitening-nourishing facial mask of nti-freckle and preparation method that one Plant Extracts extract |
| CN111450027A (en) * | 2020-05-25 | 2020-07-28 | 赵继鑫 | Whitening and freckle-removing composition, skin care product and application thereof |
| CN112656916A (en) * | 2020-12-29 | 2021-04-16 | 管晓坤 | Traditional Chinese medicine gel with whitening and freckle removing effects and preparation method thereof |
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| CN1208606A (en) * | 1997-08-18 | 1999-02-24 | 陈利华 | Face-care prepn. contg. natural ingredients |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1208606A (en) * | 1997-08-18 | 1999-02-24 | 陈利华 | Face-care prepn. contg. natural ingredients |
Non-Patent Citations (3)
| Title |
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| 化妆品美白剂;张彩华;《萍乡高等专科学校学报》;20041231(第4期);第16-18页 * |
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