CN103211990B - Chinese medicinal composition for treating oral ulcer - Google Patents

Abstract

The invention relates to a Chinese medicinal composition for treating oral ulcer. The Chinese medicinal composition is made of the following Chinese medicinal materials by weight: 10-25 parts of Pueraria, 5-15 parts of Coptis, 10-25 parts of Scutellaria, 5-20 parts of honey-fried licorice roots, 10-25 parts of almonds, 10-40 parts of coix seeds, 10-25 parts of talc, 10-25 parts of Pinellia ternate, 10-40 parts of lophatherum gracile, 10-25 parts of Tetrapanax Papyriferus, 10-40 parts of raw bighead atractylodes rhizome, 10-40 parts of honeysuckle, 5-20 parts of cassia twigs, 10-25 parts of cortex lycii radicis, 10-30 parts of bletilla striata, 10-30 parts of rhizoma phragmitis, 5-20 parts of Radix Ophiopogonis, 5-20 parts of dendrobe, 5-25 parts of Belamcanda sinensis, 5-20 parts of dragon bones, and 5-20 parts of indigo naturalis. With the efficacy of clearing away heat and purging pathogenic fire, cooling blood and eliminating toxins, clearing away heart-fire and nourishing spleen, relieving spleen and promoting tissue regeneration, the Chinese medicinal composition has obvious oral ulcer treatment effects and reliable functions. The Chinese medicinal composition disclosed in the invention has the characteristics of wide ingredient medicine sources, simple preparation, mild medicine properties, and no toxic or side effect.

Description

A kind of Chinese medicine composition for the treatment of oral ulcer

Technical field

The present invention relates to a kind of pharmaceutical product not determining structure of traditional herbal medicines, especially a kind of Chinese medicine composition for the treatment of the Chinese medicine composition of oral ulcer.

Background technology

Oral ulcer, be also called " aphtha ", it is a kind of disease that in the disease of cari oris mucosa, sickness rate is the highest, common cold, dyspepsia, psychentonia, the gloomy situation such as discomfort all can accidentally occur, be apt to occur in lip, cheek, lingual margin etc., all can occur at any position of mucosa, but attached gingiva, hard palate are then rare completely in keratinization.Age is regardless of, and age of onset was estimated between 10 ~ 20 years old, and women is more.All can occur throughout the year, ulcer has self limiting, can spontaneous recovery in about 10 days.The title recurrent aphtha if aphtha often occurs or rises one after another.Its disease damage is ulcerative lesions, and ulcer has the features such as periodicity, recurrent and self limiting.As treated not in time, Relapse rate shows effect, and it is lasting to delay, and also can transfer to " behcet's syndrome ", even involve internal organs, cause great misery to the work of patient and life.At present, clinical treatment according to different inducements, will treat the curative effect that could obtain pointedly.As: remove the pressure of psychentonia, calmness, sleeping, smoking cessation, wine etc.; For ulcer local, local can be adopted to embrocate pain relieving, antiinflammatory, the medicine of Promotive union.As: cod-liver oil paste, prednisone paste, ulcer ointment etc., or adopt hormone and antibiotic therapy with the misery of respite patient, but the infringement that the toxic and side effects such as the dysbacteriosis easily formed cause health.

The traditional Chinese medical science is thought: feelings will is unsuccessful and undermine heart spleen; Hyperactivity of fire caused by deficiency of YIN, pyretic toxicity is burnt bright, and inner clip is damp and hot, on steam the above-mentioned all diseases that to arrive in mouth.Diseases caused by exogenous pathogenic factor six climate exopathogens dryness-fire, interior impairment of ZANG FU-organs intenseness of heat is pathogenic main cause, and the dirty of main disease is the heart and spleen.

According to theory of Chinese medical science, for the pathogeny of oral ulcer, carrying out dialectical composition of prescription, take clearing away heat-fire as Therapeutic Principle, to reach the object for the treatment of both the principal and the secondary aspects of a disease at the same time.

Summary of the invention

Can only relief of symptoms and the deficiency that can not effect a permanent cure in order to overcome prior art, the invention provides a kind of prepare easy, cost is low, evident in efficacy, the Chinese medicine composition for the treatment of oral ulcer that has no side effect.

The technical solution adopted for the present invention to solve the technical problems is: a kind of Chinese medicine composition for the treatment of oral ulcer, it is characterized in that: it is made up of the raw material of Chinese medicine of following weight portion: Radix Puerariae 10-25 part, Rhizoma Coptidis 5-15 part, Radix Scutellariae 10-25 part, Radix Glycyrrhizae Preparata 5-20 part, Semen Armeniacae Amarum 10-25 part, Semen Coicis 10-40 part, Talcum 10-25 part, Rhizoma Pinelliae 10-25 part, Herba Lophatheri 10-40 part, Medulla Tetrapanacis 10-25 part, Rhizoma Atractylodis Macrocephalae 10-40 part, Flos Lonicerae 10-40 part, Ramulus Cinnamomi 5-20 part, Cortex Lycii 10-25 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 10-30 part, Rhizoma Phragmitis 10-30 part, Radix Ophiopogonis 5-20 part, Herba Dendrobii 5-20 part, Rhizoma Belamcandae 5-25 part, Os Draconis 5-20 part, Indigo Naturalis 5-20 part.

The preferred technical solution of the present invention is: a kind of Chinese medicine composition for the treatment of oral ulcer, is characterized in that: it is made up of the raw material of Chinese medicine of following weight portion: Radix Puerariae 18 parts, Rhizoma Coptidis 8 parts, Radix Scutellariae 18 parts, Radix Glycyrrhizae Preparata 10 parts, 15 parts, Semen Armeniacae Amarum, Semen Coicis 30 parts, 15 parts, Talcum, the Rhizoma Pinelliae 18 parts, Herba Lophatheri 30 parts, Medulla Tetrapanacis 15 parts, Rhizoma Atractylodis Macrocephalae 30 parts, Flos Lonicerae 30 parts, Ramulus Cinnamomi 12 parts, Cortex Lycii 15 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 20 parts, Rhizoma Phragmitis 20 parts, Radix Ophiopogonis 12 parts, Herba Dendrobii 12 parts, Rhizoma Belamcandae 15 parts, Os Draconis 10 parts, Indigo Naturalis 10 parts.

Chinese medicine composition of the present invention is under Traditional Chinese medical theory and clinical experience instruct, selected medicament composing prescription.In Chinese medicine composition of the present invention: Radix Puerariae has relieving muscles diaphoresis, invigorating YANG QI to promote eruption, antipyretic effect of promoting the production of body fluid; Rhizoma Coptidis has effect of heat clearing and damp drying, eliminating fire and detoxication; Radix Scutellariae has effect of heat clearing and damp drying, eliminating fire and detoxication, arresting bleeding and miscarriage prevention; Radix Glycyrrhizae Preparata has effect of spleen reinforcing stomach invigorating, Yiqi and vein recovery; Effect that Semen Armeniacae Amarum has expelling phlegm for arresting cough, intestine moistening of relievining asthma, the therapeutic method to keep the adverse QI flowing downwards open numbness; Semen Coicis has effect of spleen invigorating eliminating dampness by diuresis, eliminating impediment antidiarrheal, clearing away heat and discharging pus; Talcum has effect of inducing diuresis for treating stranguria syndrome, clearing away summer-heat, damp eliminating sore; The Rhizoma Pinelliae has effect of drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass; Herba Lophatheri has effect of clearing heat and relieving fidgetness, diuresis; Medulla Tetrapanacis has effect of clearing away heat and promoting diuresis, ventilation stimulating milk secretion; Rhizoma Atractylodis Macrocephalae has the antiabortive effect of invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis; Flos Lonicerae has effect of heat-clearing and toxic substances removing, wind-heat dissipating; Ramulus Cinnamomi has effect of diaphoresis expelling pathogenic factors from muscles, warming the meridian and promoting blood circulation, supporing yang activating QI, dispersing cold for relieving pain; Cortex Lycii has removing heat from blood effect except steaming, lung heat clearing pathogenic fire reducing; The Pseudobulbus Bletillae (Rhizoma Bletillae) has effect of astringing to arrest bleeding, detumescence and promoting granulation; Rhizoma Phragmitis has effect of clearing away heat and promoting production of body fluid, relieving restlessness, preventing or arresting vomiting, diuresis; There is Radix Ophiopogonis YIN nourishing and the production of body fluid promoting, effect that lung moistening clears away heart-fire; Herba Dendrobii has effect of reinforcing stomach reg fluid, nourishing YIN and clearing away heat; Rhizoma Belamcandae has effect of heat-clearing and toxic substances removing, sharp larynx expectorant; Os Draconis have effect of tranquillizing the mind by relieving convulsion, arresting sweating controlling nocturnal emission with astringent drugs, hemostasis astringing intestine to stop diarrhea, promoting tissue regeneration and ulcer healing; Indigo Naturalis has effect of heat-clearing and toxic substances removing, removing heat from blood arresting convulsion.The selected medicament composing prescription of the present invention, its drug component, through dialectical compatibility, helps using mutually assistant, plays effect of clearing away heat-fire, removing pathogenic heat from blood and toxic substance from the body, the spleen reinforcing that clears away heart-fire, pain relieving granulation promoting altogether, reach treating both the principal and secondary aspects of a disease to the treatment of oral ulcer.

The component of the present composition all adopts natural raw material of Chinese medicine, and its preparation is easy, medicine source is wide, cost is low.The present invention follows the prescriptions principle of the traditional Chinese medical science, and various component drug adopts the use that is decocted in water for oral dose.Through clinical practice checking, it is reliably evident in efficacy, mild in medicine property and, do not occur toxic and side effects, effective percentage reaches 96.7%, cure rate 75%.

Detailed description of the invention

Below in conjunction with embodiment, the invention will be further described.

Embodiment 1

Treat a Chinese medicine composition for oral ulcer, it is made up of the raw material of Chinese medicine of following weight proportion: Radix Puerariae 18g, Rhizoma Coptidis 8g, Radix Scutellariae 18g, Radix Glycyrrhizae Preparata 10g, Semen Armeniacae Amarum 15g, Semen Coicis 30g, Talcum 15g, Rhizoma Pinelliae 18g, Herba Lophatheri 30g, Medulla Tetrapanacis 15g, Rhizoma Atractylodis Macrocephalae 30g, Flos Lonicerae 30g, Ramulus Cinnamomi 12g, Cortex Lycii 15g, Pseudobulbus Bletillae (Rhizoma Bletillae) 20g, Rhizoma Phragmitis 20g, Radix Ophiopogonis 12g, Herba Dendrobii 12g, Rhizoma Belamcandae 15g, Os Draconis 10g, Indigo Naturalis 10g.

Embodiment 2

Treat a Chinese medicine composition for oral ulcer, it is made up of the raw material of Chinese medicine of following weight proportion: Radix Puerariae 20g, Rhizoma Coptidis 10g, Radix Scutellariae 15g, Radix Glycyrrhizae Preparata 5g, Semen Armeniacae Amarum 25g, Semen Coicis 40g, Talcum 12g, Rhizoma Pinelliae 20g, Herba Lophatheri 20g, Medulla Tetrapanacis 10g, Rhizoma Atractylodis Macrocephalae 10g, Flos Lonicerae 40g, Ramulus Cinnamomi 15g, Cortex Lycii 20g, Pseudobulbus Bletillae (Rhizoma Bletillae) 10g, Rhizoma Phragmitis 25g, Radix Ophiopogonis 15g, Herba Dendrobii 10g, Rhizoma Belamcandae 12g, Os Draconis 15g, Indigo Naturalis 5g.

Embodiment 3

Treat a Chinese medicine composition for oral ulcer, it is made up of the raw material of Chinese medicine of following weight proportion: Radix Puerariae 15g, Rhizoma Coptidis 5g, Radix Scutellariae 25g, Radix Glycyrrhizae Preparata 8g, Semen Armeniacae Amarum 10g, Semen Coicis 10g, Talcum 20g, Rhizoma Pinelliae 25g, Herba Lophatheri 25g, Medulla Tetrapanacis 12g, Rhizoma Atractylodis Macrocephalae 40g, Flos Lonicerae 10g, Ramulus Cinnamomi 18g, Cortex Lycii 10g, Pseudobulbus Bletillae (Rhizoma Bletillae) 25g, Rhizoma Phragmitis 15g, Radix Ophiopogonis 5g, Herba Dendrobii 15g, Rhizoma Belamcandae 20g, Os Draconis 5g, Indigo Naturalis 20g.

Embodiment 4

Treat a Chinese medicine composition for oral ulcer, it is made up of the raw material of Chinese medicine of following weight proportion: Radix Puerariae 10g, Rhizoma Coptidis 12g, Radix Scutellariae 12g, Radix Glycyrrhizae Preparata 20g, Semen Armeniacae Amarum 12g, Semen Coicis 25g, Talcum 12g, Rhizoma Pinelliae 15g, Herba Lophatheri 10g, Medulla Tetrapanacis 25g, Rhizoma Atractylodis Macrocephalae 20g, Flos Lonicerae 25g, Ramulus Cinnamomi 5g, Cortex Lycii 25g, Pseudobulbus Bletillae (Rhizoma Bletillae) 15g, Rhizoma Phragmitis 30g, Radix Ophiopogonis 10g, Herba Dendrobii 20g, Rhizoma Belamcandae 5g, Os Draconis 20g, Indigo Naturalis 12g.

Embodiment 5

Treat a Chinese medicine composition for oral ulcer, it is made up of the raw material of Chinese medicine of following weight proportion: Radix Puerariae 12g, Rhizoma Coptidis 15g, Radix Scutellariae 10g, Radix Glycyrrhizae Preparata 12g, Semen Armeniacae Amarum 20g, Semen Coicis 20g, Talcum 25g, Rhizoma Pinelliae 10g, Herba Lophatheri 40g, Medulla Tetrapanacis 20g, Rhizoma Atractylodis Macrocephalae 25g, Flos Lonicerae 15g, Ramulus Cinnamomi 20g, Cortex Lycii 12g, Pseudobulbus Bletillae (Rhizoma Bletillae) 30g, Rhizoma Phragmitis 10g, Radix Ophiopogonis 20g, Herba Dendrobii 5g, Rhizoma Belamcandae 25g, Os Draconis 12g, Indigo Naturalis 15g.

Chinese medicine composition in embodiment of the present invention decocting method routinely produces medicament.Concrete grammar is as follows: the raw material of Chinese medicine of prescription is put into container, adds cold water and covers powder, soaks 15 ~ 20 minutes, then adds water and do not have powder about 6 centimetres, decocts, and adopts intense fire to decoct at a simmer, with slow fire boiling 20 ~ 30 minutes after boiling; Second decocts, and adds water and does not have powder about 4 centimetres, decoct, and decocts 15 ~ 20 minutes after water boils.Decoct extracting juice twice, merge.

Treat a Chinese medicine composition for oral ulcer, clinical efficacy is summed up:

One, general data: this Chinese medicine composition is applied to clinical observation case 60 example, 15 ~ 50 years old age.

Two, diagnosis basis:

1, occur ulcer that is single or several diameter 3 ~ 5mm with oral mucosa, scorching hot pain is cardinal symptom;

2, onset is very fast, healing in general about 7 days, if down here, then the course of disease extends.More normal easily recurrence after;

3, examination of mouth: stomatocace is comparatively shown shallow, circular or oval, quantity 1 ~ 2 at least, more than 10 at most, surface has faint yellow secretions to adhere to, and ulcer surrounding mucosa is mostly congested;

4, should differentiate mutually with inflammation around hu huo syndrome (behcet's syndrome), Periadenitis mucosa and herpetic stomatitis.

Three, usage and dosage: during clinical practice, the amounts of components in compositions takes the circumstances into consideration increase and decrease according to the body weight of patient and age.Potion on the one, decocting twice extracting juice is about 300ml, and point morning, evening take for twice.

Four, criterion of therapeutical effect:

(1) cure: oral ulcer heals, local is without sense of discomfort;

(2) take a turn for the better: although have recurrence during aphtha, quantity reduces, and degree alleviates;

(3) do not heal: aphtha symptom and ulcer are without significant change.

Five, therapeutic effect: in this clinical observation case, take medicine 1-15 days, recovery from illness 45 example, follows up a case by regular visits to and has no recurrence; Take a turn for the better 13 examples, invalid 2 examples.There is not toxic and side effects in treatments period.

Six, model case:

Case 1:

Zhang, female, 36 years old.Oral cavity repeatedly ulcer situation has occurred 1 year, through repeatedly western medicine, invalid.Take medicament 5 days prepared by Chinese medicine composition of the present invention, ulcer area and number reduce; Continue and take 3 days, oral ulcer heals, and cures.

Case 2:

Lin, man, 30 years old.Patient's readme: oral ulcer, mouth are sticky, happiness drink, oral ulcer, low grade fever, malaise.Take medicament 7 days prepared by Chinese medicine composition of the present invention, ulcer level alleviates, and other symptoms obviously alleviate; Continue and take 7 days, oral ulcer heals, and follows up a case by regular visits to and has no recurrence half a year.

Claims (1)

1. treat a Chinese medicine composition for oral ulcer, it is characterized in that: it is made up of the raw material of Chinese medicine of following weight proportion: Radix Puerariae 20g, Rhizoma Coptidis 10g, Radix Scutellariae 15g, Radix Glycyrrhizae Preparata 5g, Semen Armeniacae Amarum 25g, Semen Coicis 40g, Talcum 12g, Rhizoma Pinelliae 20g, Herba Lophatheri 20g, Medulla Tetrapanacis 10g, Rhizoma Atractylodis Macrocephalae 10g, Flos Lonicerae 40g, Ramulus Cinnamomi 15g, Cortex Lycii 20g, Pseudobulbus Bletillae (Rhizoma Bletillae) 10g, Rhizoma Phragmitis 25g, Radix Ophiopogonis 15g, Herba Dendrobii 10g, Rhizoma Belamcandae 12g, Os Draconis 15g, Indigo Naturalis 5g.