CN103099426B - Oral care implement - Google Patents
Oral care implement Download PDFInfo
- Publication number
- CN103099426B CN103099426B CN201310049393.0A CN201310049393A CN103099426B CN 103099426 B CN103099426 B CN 103099426B CN 201310049393 A CN201310049393 A CN 201310049393A CN 103099426 B CN103099426 B CN 103099426B
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- China
- Prior art keywords
- soft tissue
- head
- cleaning device
- dental treatment
- fritter
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- 238000004140 cleaning Methods 0.000 claims abstract description 63
- 239000013536 elastomeric material Substances 0.000 claims abstract description 10
- 238000011282 treatment Methods 0.000 claims description 34
- 210000004872 soft tissue Anatomy 0.000 claims description 29
- 230000002093 peripheral effect Effects 0.000 claims description 8
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- KRHYYFGTRYWZRS-UHFFFAOYSA-M Fluoride anion Chemical compound [F-] KRHYYFGTRYWZRS-UHFFFAOYSA-M 0.000 description 6
- 208000032139 Halitosis Diseases 0.000 description 6
- 230000001680 brushing effect Effects 0.000 description 6
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- 238000011160 research Methods 0.000 description 4
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 3
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 description 3
- 230000001580 bacterial effect Effects 0.000 description 3
- 239000011248 coating agent Substances 0.000 description 3
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- 230000002906 microbiologic effect Effects 0.000 description 3
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- 229920000742 Cotton Polymers 0.000 description 2
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- 238000004458 analytical method Methods 0.000 description 2
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- 239000006228 supernatant Substances 0.000 description 2
- 125000003831 tetrazolyl group Chemical group 0.000 description 2
- RWSOTUBLDIXVET-UHFFFAOYSA-N Dihydrogen sulfide Chemical compound S RWSOTUBLDIXVET-UHFFFAOYSA-N 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- LSDPWZHWYPCBBB-UHFFFAOYSA-N Methanethiol Chemical compound SC LSDPWZHWYPCBBB-UHFFFAOYSA-N 0.000 description 1
- 229920000297 Rayon Polymers 0.000 description 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical class [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 description 1
- 239000005864 Sulphur Substances 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 239000011324 bead Substances 0.000 description 1
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- 239000000203 mixture Substances 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 239000002324 mouth wash Substances 0.000 description 1
- 229940051866 mouthwash Drugs 0.000 description 1
- VMGAPWLDMVPYIA-HIDZBRGKSA-N n'-amino-n-iminomethanimidamide Chemical compound N\N=C\N=N VMGAPWLDMVPYIA-HIDZBRGKSA-N 0.000 description 1
- NJPPVKZQTLUDBO-UHFFFAOYSA-N novaluron Chemical compound C1=C(Cl)C(OC(F)(F)C(OC(F)(F)F)F)=CC=C1NC(=O)NC(=O)C1=C(F)C=CC=C1F NJPPVKZQTLUDBO-UHFFFAOYSA-N 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 229920005996 polystyrene-poly(ethylene-butylene)-polystyrene Polymers 0.000 description 1
- 238000012805 post-processing Methods 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- BOLDJAUMGUJJKM-LSDHHAIUSA-N renifolin D Natural products CC(=C)[C@@H]1Cc2c(O)c(O)ccc2[C@H]1CC(=O)c3ccc(O)cc3O BOLDJAUMGUJJKM-LSDHHAIUSA-N 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
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- -1 sulphur compound Chemical class 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 241001148471 unidentified anaerobic bacterium Species 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A46—BRUSHWARE
- A46B—BRUSHES
- A46B9/00—Arrangements of the bristles in the brush body
- A46B9/06—Arrangement of mixed bristles or tufts of bristles, e.g. wire, fibre, rubber
-
- A—HUMAN NECESSITIES
- A46—BRUSHWARE
- A46B—BRUSHES
- A46B15/00—Other brushes; Brushes with additional arrangements
- A46B15/0002—Arrangements for enhancing monitoring or controlling the brushing process
-
- A—HUMAN NECESSITIES
- A46—BRUSHWARE
- A46B—BRUSHES
- A46B15/00—Other brushes; Brushes with additional arrangements
- A46B15/0002—Arrangements for enhancing monitoring or controlling the brushing process
- A46B15/0016—Arrangements for enhancing monitoring or controlling the brushing process with enhancing means
- A46B15/0032—Arrangements for enhancing monitoring or controlling the brushing process with enhancing means with protrusion for polishing teeth
-
- A—HUMAN NECESSITIES
- A46—BRUSHWARE
- A46B—BRUSHES
- A46B15/00—Other brushes; Brushes with additional arrangements
- A46B15/0055—Brushes combined with other articles normally separate from the brushing process, e.g. combs, razors, mirrors
-
- A—HUMAN NECESSITIES
- A46—BRUSHWARE
- A46B—BRUSHES
- A46B15/00—Other brushes; Brushes with additional arrangements
- A46B15/0055—Brushes combined with other articles normally separate from the brushing process, e.g. combs, razors, mirrors
- A46B15/0081—Brushes with a scraper, e.g. tongue scraper
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/24—Surgical instruments, devices or methods for use in the oral cavity, larynx, bronchial passages or nose; Tongue scrapers
- A61B17/244—Surgical instruments, devices or methods for use in the oral cavity, larynx, bronchial passages or nose; Tongue scrapers for cleaning of the tongue
-
- A—HUMAN NECESSITIES
- A46—BRUSHWARE
- A46B—BRUSHES
- A46B2200/00—Brushes characterized by their functions, uses or applications
- A46B2200/10—For human or animal care
- A46B2200/1066—Toothbrush for cleaning the teeth or dentures
Landscapes
- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Otolaryngology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Dentistry (AREA)
- Biomedical Technology (AREA)
- Pulmonology (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Brushes (AREA)
- Cosmetics (AREA)
Abstract
An oral care implement with a handle includes a head with a tissue cleanser. The tissue cleanser may be a pad composed of an elastomeric material. The pad is disposed on the head on a surface opposite the tooth cleaning elements. The tissue cleanser may include a plurality of nubs extending for cleaning between the papillae of the tongue. The tissue cleanser may include a plurality of conically shaped nubs. A tissue cleanser can be used to reduce oral epithelial cells.
Description
The application is the divisional application that the application number submitted on June 18th, 2004 is 200480017113.7 (application number of its divisional application is 201110066653.6), denomination of invention is the application for a patent for invention (international application no: PCT/US 2004/019541) of " dental treatment ".
Technical field
The present invention relates to a kind of dental treatment had for the cleaning device of soft tissue surfaces in clean mouth.
Background technology
According to ADA, the main cause of Healthy People halitosis is the microbe deposition on tongue, and wherein bacterial coating harbors is produce the biology of halitosis and micro-bits provide environment.Papillary nature due to tongue surface creates the very large unique ecological contributing to oral bacteria and assemble of surface area, and tongue is the paradise of microbial growth.Anaerobic bacteria flora on tongue and bacterium play very important effect for the formation of chronic bad (being commonly referred to halitosis).In general, bacteria produce volatile sulfur compounds (VSC).If have accumulated enough sulphur compounds, halitosis or oral malodor will be caused.
Although employed the tongue scraper that blade (bladed) is housed in the past, these tongue scrapers are not enough to the effect of tongue soft tissue surfaces.Wide flat scraping blades arrives that to assemble between bacterium and the tongue mastoid process of micro-bits limited in one's ability.In addition, although the ability of clean tongue can obtain advantage, some users do not use this blade, in default of the comfort of tongue surface.
Thus, need a kind of have effectively remove the dental treatment that tongue bacteria and other micro-bits ensure the Tongue cleanser that user is comfortable simultaneously.
Summary of the invention
The present invention relates to a kind of have to provide improve clean and effectively remove the dental treatment of the bacterium of oral tissue surfaces deposition and the tissue cleanser of micro-bits.
In one aspect of the invention, this tissue cleanser comprises multiple fritter (nub) for soft tissue surfaces in clean mouth and between the tongue mastoid process being used in particular for clean tongue.Of the present invention another preferred in, tissue cleanser comprises multiple conical fritter.
In another aspect of this invention, tissue cleanser is made up of elastomeric material.In a preferred embodiment, tissue cleanser is formed as being arranged on the elastomeric pad of dental treatment brush, so as to improve cleaning effect, be easy to manufacture and make user feel comfortable.
In another aspect of this invention, dental treatment comprises pedestal, to facilitate and easily tissue cleanser to be molded on brush.In a preferred structure, brush has one or more protrusion for grappling brush in the molding process of tissue cleanser.Brush can also comprise tray, to limit the appearance profile of molded tissue cleanser further.
In another aspect of this invention, dental treatment comprises the tissue cleanser had for device oral volatile sulfur compounds being reduced 35% from the benchmark measured with latter two hours.
In another aspect of this invention, dental treatment is provided with tooth cleaning components and tissue cleanser, so that the oral surfaces of thorough cleaning teeth, gum, tongue and cheek and lip.In preferred structure, tooth cleaning components and tissue cleanser are supported on the opposite side of support brush.
In another aspect of this invention, at least one element of tooth cleaning components and tissue cleanser form as one formula component by the dental treatment comprising tooth cleaning components and tissue cleanser.
Accompanying drawing explanation
By considering that appended accompanying drawing can more fully understand the present invention and advantage thereof with reference to subsequent descriptions, wherein identical Reference numeral represents identical feature, wherein:
Fig. 1 is the decomposition assembling view of the dental treatment of one or more aspects according to illustrative examples;
Fig. 2 is the enlarged perspective of the brush of the dental treatment of Fig. 1;
Fig. 3 is the plane of the dental treatment of Fig. 1 of display tongue cleaning feature;
Fig. 4 is the partial cross section figure of the dental treatment brush of Fig. 1 of 4-4 line along Fig. 3;
Fig. 5 is the plane of the dental treatment of Fig. 1 of at least one cleaning of teeth structure of display;
Fig. 6 is the perspective view of the dental treatment of display tooth cleaning components example; And
Fig. 7 is the sectional view of the alternative construction of dental treatment brush.
Detailed description of the invention
In subsequent descriptions, for toothbrush, the present invention will be discussed, but the present invention can adopt other dental treatment form only comprising tissue cleanser.In addition, need be appreciated that and can use other embodiment and can structural and functional modifications be carried out in the situation not departing from the scope of the invention.
Fig. 1-Fig. 7 shows a kind of dental treatment (such as toothbrush) 100, and it has brush holder 103 and may be used for the brush 105 of soft tissue in cleaning teeth and mouth (such as, tongue, cheek interior surface, lip or gum).Arrange brush holder 103 catch easily for making user and handle toothbrush, and can be formed by many difformities and structure.Although brush usually will wider than the neck of brush holder, brush can be that the simple of brush holder extends continuously or shrink in some configurations.In preferred structure, brush 105 has first surface 106(Fig. 5 and Fig. 6 of supports tooth cleaning element 107) and second 108(Fig. 2 and Fig. 3 of supporting tissue cleaning device 300).First and second faces 106,108 are preferably placed at the opposite side of brush 105.But, tissue cleanser 300 can be arranged on other places, the near-end 104 of such as brush holder 103.Extend further on the peripheral sidewall surface 101 that tissue cleanser 300 or part cleaning device can also be positioned at brush 105 or than the illustrated near-end 104 to brush holder 103.
The elastomeric material of tissue cleanser 300 can be any biocompatible elastomeric material being applicable to oral hygiene apparatuses.In order to provide optimum reelability quality and cleaning effect, the hardness property of elastomeric material is preferably between Durometer A hardness 8 to A25.As an example, a kind of preferred elastomeric material is the styrene-ethylene/butylene-styrene block copolymer (SEBS) that GLS Corp. produces.But, other material within the SEBS material of other manufacturer or above-mentioned hardness range or in addition can be used.
Tissue cleanser 300 preferred disposition has multiple tissues counterpart 303(Fig. 1-Fig. 4), in preferred structure, tissue engaging element 303 is formed with fritter form." fritter " that use in the application generally expression comprises the cylindrical projections (do not limit the cross sectional shape of projection) upright from bottom surface.In general sense, in preferred structure, the height of fritter is greater than the width (measuring on most length direction) bottom fritter.But, fritter can comprise width and highly roughly equal or be highly slightly less than the projection of bottom width.In addition, in some cases (such as, fritter terminad be tapered or comprise to less raised narrow bottom time), bottom width can much larger than height.
This tissue engaging element 303 is designed to the main source of halitosis in obvious reduction crowd and improves health.Fritter 303 can remove microbiologic population and other micro-bits of soft tissue surfaces in tongue and other mouthful.Tongue especially easily forms bacterial coating harbors, and the biology that bacterial coating harbors is generation halitosis and micro-bits provide environment to be known.This microbiologic population can be found in depression between the tongue mastoid process in most of region of tongue upper surface and along soft tissue surfaces in other mouth.When coordinating with tongue surface or promote against tongue surface, such as elastomeric tissue cleanser 300 fritter 303 arrives in the depression of tongue adjacent papillae downwards with soft tissue gentle engagement simultaneously.The elastic construction of tissue cleanser 300 can also make bottom surface 301 along the natural contour motion of oral tissue surfaces (such as, the tongue of user, cheek, lip and gum).In addition, soft fritter 303 can bend, in a desired manner to cross and to clean fritter along soft tissue surfaces in the mouth of movement.
As in Fig. 2 and Fig. 4 see, in a preferred disposition of tissue cleanser 300, fritter 303 is preferably conical.As used in this application, " conical " or " circular cone " represent comprise pure circular cone, conical butt element and other be tapered and shape similar with circular cone thus to narrow end, no matter these shapes whether evenly, tapering whether continuously, whether there is circular cross-section.See Fig. 4, the bottom 305 of each conical tissue counterpart 303 is greater than respective end 307.In this taper shape configuration, the wider cross-sectional area of bottom 305, to provide effective shear strength to stand the lateral movement of tissue cleanser 300 along tongue surface or other soft tissue surfaces.The end 307 of less width or diameter enables fritter inswept in tongue or other depression in the surface, to clean microbe deposition and other micro-bits from soft tissue surfaces in conjunction with the length of conical fritter 303.In preferred structure, in use, along with the applying of lateral pressure, fritter 303 can bend from respective vertical axis and bend.This flexing enhances the clean of comfort and soft tissue surfaces.In preferred structure, the thickness bottom fritter or width are 0.64 millimeter and preferably from about 0.51 millimeter to about 2.00 millimeters.The end 307 of fritter is 0.127 millimeter and preferably between about 0.10 millimeter to about 0.75 millimeter, most desirably to thrust in the depression of user's tongue tongue mastoid process.Measure the length of the fritter 303 of end 307 from bottom surface 301 or be highly preferably 0.91 millimeter and preferably about 0.5 millimeter to about 2.5 millimeters, preferably between 0.75 millimeter to 1.5 millimeters.But, the fritter of other size and dimension beyond given range can be used.
Optionally, tissue cleaning elements 303 can be other shape.As an example, tissue cleanser can have such as co-pending U.S. Patent application No.10/601, and the grid described by 106, this application is incorporated herein by reference.
In preferred structure, fritter 303 is arranged on the bottom surface 301 of tissue cleanser 300 in a high density pattern.The interval of each fritter 303 and adjacent isles 303 is preferably between about 0.5 millimeter to about 3 millimeters; Preferred interval between 0.7 millimeter to 2.5 millimeters, and preferably between 1 millimeter to 2 millimeters.But, other interval can be used.The surface density of the fritter 303 on bottom surface 301 is preferably per square inch between about 100 to about 600 fritters.In the more preferably structure of tissue cleanser, surface density per square inch between 200 to 500 fritters, preferably per square inch between 300 to 450 fritters.In a preferred embodiment, tissue cleanser 300 comprises about 400 fritters in surface area per square inch.The surface density integrate features height of fritter 303 enables tissue cleanser strengthen cleaning of soft tissue surfaces and improve comfort level.But, other surface density can be used.
As seen in figure 3, fritter 303 is preferably arranged in the stringer on the direction being basically parallel to longitudinal axis a-a.In addition, fritter 303 is arranged on and is parallel to bottom surface 301 and is basically perpendicular to walking crosswise in RI, R2 on the axis of longitudinal axis a-a.In a preferred structure, bottom surface 301 provides adjacent fritter 303 with the configuration of staggering.Such as, the adjacent Rl of walking crosswise of fritter and R2 has and is not located immediately at fritter 303 below each other.When the first fritter is positioned at the lateral extent of the second fritter extending longitudinally, then the first fritter is claimed to be located immediately at after the second fritter.This configuration is by promoting that removing microbiologic population can improve the clean of soft tissue surfaces with other micro-bits (especially removing in the depression of the adjacent papillae of tongue).But.Can at random or with countless these fritters of different style configuration.
Although other manufacturing process can be used, form Tongue cleanser 300 preferably by the mode be molded on brush 105.See Fig. 1 and Fig. 4, in the tray that tissue cleanser 300 is preferably molded in the face 108 of brush 105 or container cavity 111.Container cavity 111 has bottom surface 113 and from the outward extending peripheral sidewall 115 of bottom surface 113.In an assembled configuration, the fritter 303 of tissue cleanser 300 exposes, together to use with the bottom surface of tissue cleanser 300, and this bottom surface or opposing recesses concordant with head surface 114.But, other oriented approach can be used.Equally, the bottom surface 301 of tissue cleanser can embed in brush 105 or covered by other layer, and wherein, fritter 303 is given prominence to by suitable opening.
As can be seen in figures 1 and 4, face 108 preferably also comprises one or more peg members 117a-c be arranged in tray 111.Peg members 117 defines the anchor point being close to opposing mold, moves under injection pressure to prevent brush.Thus, tissue cleanser 300 preferably includes one or more complimentary aperture 311a-c that peg members 117a-c top is exposed.Although the center line (such as, longitudinal axis a-a) that dowel pin is shown as along brush is aimed at, dowel pin can have many different location.In addition, brush 105 preferably includes dowel pin and tray, but also can use another when neither one.
Optionally, tray 111 and peg members 117a-c can be provided, to locate and to fix tissue cleanser molded in advance, although these structures are not use this tissue cleanser molded in advance necessary.
Peg members 117a-c can adopt various shape and length.Continue with reference to Fig. 1 and Fig. 4, brush 105 comprises the peg members 117a-c extending outwardly into peripheral sidewall 115 height from the bottom surface 113 of tray 111.Peg members 117a-c is configured as cylindrical, but peg members 117a-c can be other shape or length.Although preferably use moulding process to be attached on brush by tissue cleanser, viscose glue or other known approaches can be used to be formed and conjunctive tissue cleaning device.
As Figure 1-Figure 4, tissue cleanser 300 is preferably formed to the pad comprising flexible resilient material, so that comfortable cleaning and effectively remove bacterium and the micro-bits even along lip deposition in soft tissue surfaces in tongue and other mouthful.Tissue cleanser 300 also provides effective massage, stimulation remove tongue, cheek, gum and the bacterium on lip surface, micro-bits and epithelial cell.
In preferred structure (Fig. 1-Fig. 6), when user of toothbrushing, tissue cleanser 300 can rub in the side of tongue to the inner surface of cheek or lip, and thus provides desired massage, stimulation and clean to the various soft tissue surfaces in mouth.Such as, in the process of brush facial tooth surfaces, the oral surfaces being arranged on the tissue cleanser 300 pairs of cheek on the outer surface 108 of brush 105 carries out nature friction.Thus, the cleaning effect of enhancing is obtained when not needing additional cleaning step.In addition, some user can feel the excitant pain on cheek surfaces, and this pain causes the active responding of user, or even the enjoyment of the comfort of the tissue cleanser of soft tissue surfaces in bead.Tissue cleanser 300 can also rub extraly on cheek, tongue etc., and this can be used as the another kind of cleaning mode desired by except the contact produced when brushing teeth.
With reference to Fig. 5 and Fig. 6, the tooth cleaning components 107 of brush 105 can comprise the multiple tooth cleaning components for wiping, clean and massage user's tooth and gum.The tooth cleaning components of any appropriate format can be used.Use term " tooth cleaning components " with upperseat concept, it represents the filament bristles or resilient fingers or wall-like thing with any desirable shape.In the example shown in Fig. 5, tooth cleaning components 107 comprises longitudinal tooth cleaning components 207a-c, arcuate tooth cleaning elements 209a-d and 211a-b that the distal tooth cleaning elements 203a-b, the peripheral tooth cleaning element 205a-l, longitudinally a-a that are arranged on brush 105 far-end 121 is arranged, and Proximal cleaning elements 213a, b.Preferably provide tooth cleaning components 205,207,211 and 213 with the form of brushing cluster, but preferably form tooth cleaning components 209 with the form of elastic wall.But, the tooth cleaning components of other form and type can be used.
Fig. 7 shows the sectional view of the alternative configurations of toothbrush head 400.The structure of brush 400 is similar to brush 105, except tooth cleaning components 209a-d and tissue cleanser 300 monoblock type are formed.In order to realize alternative construction, brush 400 has the port or opening 401 that size suitably customizes, to make elastomeric material flow through brush in injection moulding process.In such an embodiment, tooth cleaning components 209a-d and tissue cleanser 300 are formed by same resilient material.Thus, brush 400 can comprise at least one and tissue cleanser 300 and to form as one the elasticity tooth cleaning components of formula element.
Various change can be carried out without departing from the present invention to above method, composition and structure, all the elements of the application all should only be interpreted as exemplary at (comprising above-mentioned interactional all mechanism and/or pattern), and limit the scope of claims never in any form.
Subsequent instance is set forth with the representative of operation improving of the present invention.These examples are not construed as limiting the scope of the invention.
Example 1
Known oral malodor assessment methods is used to measure the performance of toothbrush.Carry out studying to assess the performance of the toothbrush preferred structure of toothbrush 100 (such as, as discussed above) being provided with the elastomeric tissue cleanser with conical fritter.Tested crowd take part in this research.Be cleaning or normalization period before the test of about 7 days, wherein testee brushes teeth twice by fluoride dental cream (see table 1) every day.After a washout period, require testee oral cavity test before do not carry out any oral hygiene (brush teeth, rinse and bracing wire clean), feed and drinking-water.Baseline volatile sulphur compound (VSC) sample is extracted from each testee.In the research controlled for overnight odor, testee uses the toothbrush 100 being provided with tissue cleanser 300 mentioned above to utilize fluoride dental cream (see table 1) to brush teeth one minute.Next, testee utilizes the tissue engaging element of toothbrush to clean tongue surface ten second.Testee sleeps night return and carry out post processing.The time point cleaning ten hours in distance the previous day extracts VSC sample.In exemplary embodiment, compared with being only to brush teeth, toothbrush is used to make oral cavity VSC reduce 60% from the benchmark measured with rear ten hours.VSC reading can be obtained by gas chromatographic analysis.
Example 2
In another research of toothbrush 100 mentioned above, be cleaning or normalization period before the test of about 7 days, wherein testee brushes teeth twice by fluoride dental cream (see table 1) every day.Require testee do not carry out before test any oral hygiene (brush teeth, rinse and bracing wire clean), feed and drinking-water.After a washout period, the baseline tongue bacteria sample by utilizing the dorsal part of disinfecting cotton swab wiping tongue to provide testee.Testee uses to have and utilizes fluoride dental cream (see table 1) to brush teeth one minute by the toothbrush of tissue cleanser mentioned above.Next, testee utilizes the preferred structure of the tissue engaging element 300 of toothbrush 100 to clean tongue surface ten second.Clean tongue surface, after two hours, utilizes cotton swab to extract tongue bacteria sample from tongue dorsal part.In exemplary embodiment, the use of tissue bond element more can control to produce the tongue bacteria of stink than only brushing teeth simply.The use of tissue cleanser 300 prove to use on tongue the logarithm of tongue bacteria after two hours be reduced beyond every milliliter in 0.8 times of Log colony forming units.
Example 3
In another research of toothbrush mentioned above, from the epithelial survival ability of oral collection before and after the toothbrush using MTT test to check to use and there is above-mentioned tissue cleanser.MTT test is based on the tetrazolium had in the living cells of metabolic activity
the enzyme reduction of salt MTT [3-(4,5-dimethyl-2-thiazole)-2,5-diphenyl bromination tetrazoliums +++].In test tube, carry out real time reaction, and use porous culture plate reader to measure product (being dissolved in the purple formazan in dimethyl formamide) with colorimetric method.Advantageously, MTT experimental accuracy is high, easy to use and be applicable to extensive chemical sensitivity tests.
After the wash phase of 7 days, testee reports to test base when not taking food, drinking water or carrying out oral hygiene in advance.Testee in vitro provides salivary rinse sample by what utilize 9 ml sterile waters to gargle to be equipped with in 10 seconds being spued by mouthwash 10x SPBS (PBS) solution.By freezing for sample about 30 minutes before carrying out MTT test.Testee uses fluoride dental cream (see table 1) to brush teeth then to utilize for one minute the Tongue cleanser 300 of preferred structure to clean tongue 10 second under guidance.About 30 minutes after brushing and tongue cleaning, testee provided rinse samples with previously described method.
Rinse samples before and rinse samples afterwards to be carried out with about 3000RPM centrifugal 15 minutes.Remove supernatant (such as, clear liquid) and particle is suspended in the PBS of 2.5 milliliters.Make sample whirling motion 5 second, to add 2.5 milliliters of MTT solution subsequently.Then culture sample 2 hours in the soft shaking bath being set as 37 DEG C.After the cultivation stage of 2 hours, sample to be carried out with about 3000 RPM centrifugal 15 minutes.Supernatant liquor sucking-off is added 3 milliliters of detergents (0.04 N acid isopropyl alcohol), so that dissolve purple crystals.MTT transform increase or be reduced by spectral measurement method quantize.From each sample, take out 200 microlitres join in 96 well plates, and measure the optical density of 570 nanometers and compare with negative cushioning control.In exemplary embodiment, brushing teeth, then using-system cleaning device 10 second can by mouth epithelial cells from the determined value reduction 72% of MTT test protocols in one minute.
Example 4
In another study, tested crowd passes through Halimeter
tM(i.e. sulfide meter) provides benchmark VSC sample.Halimeter
tMuse when being exposed to VSC(such as, sulfide and mercaptan gases) time produce signal electrochemistry voltammetric sensor and with the precision measure sulfureted hydrogen gas concentration of parts per billion (ppb).Testee utilizes the toothbrush one minute of the preferred structure with tissue cleanser mentioned above under guidance.Subsequently, tester uses above-mentioned toothbrush to knock six times at tongue surface.Follow-up VSC sample is extracted from testee after two hours at brushing stage.In exemplary embodiment, use the toothbrush with tissue cleanser that the VSC measured in implication is reduced more than 35% from the benchmark measured with latter two hours.
Example 5
In another study, after a washout period, tested crowd utilizes sterilized water to gargle to be provided for utilizing MTT to test the baseline sample of carrying out viable epithelial cell analysis.Testee utilizes the toothbrush one minute of the preferred structure with tissue cleanser mentioned above under guidance.Subsequently, tester uses above-mentioned toothbrush to knock six times at tongue surface.Testee be provided for analyze gargling after sample.The method discussed for example 3 is utilized to test and analyze this sample.In this example, use toothbrush that oral epithelial cells is reduced about 92% from the benchmark determined by MTT analysis agreement.
In example mentioned above, testee uses and is brushed teeth by the fluoride dental cream of table 1 equation expression.
Table 1
Claims (15)
1. a dental treatment, comprising:
Head and shank;
Multiple tooth cleaning components, its first surface from described head extends;
Container cavity, it is formed in relative with described first surface second of described head;
Soft tissue cleaning device, it is formed by the elastomeric material be injected in described container cavity, and described soft tissue cleaning device comprises multiple projection; With
One or more peg members, its bottom surface from described container cavity extends, and described soft tissue cleaning device comprises one or more complimentary aperture, and each complimentary aperture is held a corresponding peg members and the top of a described corresponding peg members is exposed.
2. dental treatment according to claim 1, is characterized in that, described container cavity comprises from the outward extending peripheral sidewall of described bottom surface.
3. dental treatment according to claim 2, is characterized in that, described one or more peg members extends to the height of described peripheral sidewall from the bottom surface of described container cavity.
4. dental treatment according to claim 1, is characterized in that, described one or more peg members is aimed at along the longitudinal axis of described head.
5. dental treatment according to claim 1, is characterized in that, described multiple projection comprises multiple fritter.
6. dental treatment according to claim 1, is characterized in that, described multiple projection extends beyond second of described head.
7. dental treatment according to claim 1, is characterized in that, described soft tissue cleaning device is pad.
8. dental treatment according to claim 1, is characterized in that, described tooth cleaning components comprises bristle.
9. a dental treatment, comprising:
Shank;
Head, it has longitudinal axis;
Multiple tooth cleaning components, its first surface from described head extends;
Container cavity, it is formed in relative with described first surface second of described head, and described container cavity comprises from the outward extending peripheral sidewall of bottom surface;
Soft tissue cleaning device, it is by being injected into be formed by the elastomeric material that described soft tissue cleaning device is attached on described head in described container cavity, and described soft tissue cleaning device comprises multiple fritter, and described fritter extends beyond second of described head; With
At least one peg members, it is aimed at along described longitudinal axis and extends from the bottom surface of described container cavity, and described soft tissue cleaning device comprises at least one complimentary aperture, and each complimentary aperture makes the top of a corresponding peg members expose.
10. dental treatment according to claim 9, is characterized in that, at least one peg members described extends to the height of described peripheral sidewall from the bottom surface of described container cavity.
11. dental treatments according to claim 9, is characterized in that, each in described multiple fritter is configured as taper shape.
12. dental treatments according to claim 9, is characterized in that, described tooth cleaning components comprises bristle.
13. dental treatments according to claim 9, is characterized in that, each in described multiple fritter comprises bottom and end, and described bottom has the cross-sectional area wider than described end.
14. dental treatments according to claim 13, is characterized in that, the bottom of described multiple fritter is spaced apart from each other.
15. 1 kinds of dental treatments, comprising:
Head and shank, described head has longitudinal axis;
Multiple tooth cleaning components, its first surface from described head extends;
Soft tissue cleaning device relative with described first surface on described head, described soft tissue cleaning device is by being injected into be formed by the elastomeric material that described soft tissue cleaning device is attached on described head on described head, and described soft tissue cleaning device comprises multiple projection;
At least one peg members, it is aimed at along described longitudinal axis and extends from described head, and described soft tissue cleaning device comprises at least one complimentary aperture, and each complimentary aperture makes the top of a corresponding peg members expose.
Applications Claiming Priority (10)
Application Number | Priority Date | Filing Date | Title |
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US10/601,106 | 2003-06-20 | ||
US10/601106 | 2003-06-20 | ||
US10/601,106 US20040255416A1 (en) | 2003-06-20 | 2003-06-20 | Toothbrush with tongue cleaning member |
US29/189,729 | 2003-09-10 | ||
US29/189,729 USD517812S1 (en) | 2003-09-10 | 2003-09-10 | Toothbrush |
US29/189729 | 2003-09-10 | ||
PCT/US2003/029497 WO2004026162A2 (en) | 2002-09-20 | 2003-09-17 | Toothbrush with gripping area |
USPCT/US03/29497 | 2003-09-17 | ||
USPCT/US03/30633 | 2003-09-26 | ||
PCT/US2003/030633 WO2004028235A2 (en) | 2002-09-27 | 2003-09-26 | Toothbrush |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CN2004800171137A Division CN1809301B (en) | 2003-06-20 | 2004-06-18 | Oral care implement |
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CN103099426A CN103099426A (en) | 2013-05-15 |
CN103099426B true CN103099426B (en) | 2015-04-01 |
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CN201210307256.8A Expired - Fee Related CN102783811B (en) | 2003-06-20 | 2004-06-18 | A kind of toothbrush |
CN2011100666536A Expired - Fee Related CN102132995B (en) | 2003-06-20 | 2004-06-18 | Oral care implement |
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CN201210307256.8A Expired - Fee Related CN102783811B (en) | 2003-06-20 | 2004-06-18 | A kind of toothbrush |
CN2011100666536A Expired - Fee Related CN102132995B (en) | 2003-06-20 | 2004-06-18 | Oral care implement |
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CN (3) | CN103099426B (en) |
AU (3) | AU2004249249B2 (en) |
BR (1) | BRPI0411539B1 (en) |
CA (5) | CA2842174C (en) |
IN (2) | IN2015DN00952A (en) |
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TW (3) | TWI260976B (en) |
WO (2) | WO2004112538A1 (en) |
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