CN103076441B - Biosensing measurement system with two-way verification of test piece information - Google Patents

Abstract

A biological sensing measurement system with test piece information capable of being checked bidirectionally comprises a test piece structure and a measurement device; the test strip structure comprises a biological sensing unit for generating at least one reaction signal, a test strip with a surface, and characters with identifiability arranged on the surface. The measuring device comprises an image capturing unit for capturing an image, a test piece information obtaining unit for obtaining an obtained character according to the image, a user interface unit for outputting corresponding to the image and carrying out a checking operation, a judging unit for receiving a checking operation signal to judge, and a signal measuring unit; when the test piece information confirms that the test piece is correct, the signal measuring unit obtains a measuring result according to the obtained character and the reaction signal.

Description

Biosensing measurement system with two-way verification of test piece information

technical field

The invention relates to a biosensor measuring system (biosensor measuring system) and a detection test piece structure used in the biosensor measuring system.

Background technique

Diabetes is a common disease. Due to the trend of population growth, aging, obesity, unhealthy diet and sedentary lifestyle, the incidence of diabetes worldwide is rapidly increasing. If diabetic patients are not properly treated or treated incorrectly, they are most likely to cause many complications, such as retinal Complications such as stripping, heart failure, unstable blood pressure, hyperlipidemia, stroke and hemiplegia, etc. Therefore, blood sugar control can be effectively prevented and treated in time to reduce the occurrence of regret. Furthermore, diabetes is a chronic disease that requires long-term care and treatment. In order to track the blood sugar index of diabetic patients at any time, and to accurately grasp the control of the patient's condition, some related companies have developed a home-based bio-sensing measurement system to do a tracking and recording work.

At present, the biosensing measurement system is through the cooperation of the detection test piece and the measurement device. Generally, the test piece information of the detection test piece is coded to form coded information, which is used to provide the identification of the measurement device; the existing biosensing measurement system , taking China Taiwan Patent Publication No. 201015064 and U.S. Patent No. 7695608 as an example, the detection test piece used has an optically readable pattern (Optically Readable Pattern) such as a one-dimensional or two-dimensional barcode, or at least one infrared ray Reflection/absorption marks (infrared absorption/reflection mark) are used as encoded information. The pattern and mark are related to the test piece information of the detection test piece, for example, the type of the test piece, the lot number (lot number), etc., and the test piece information is used for reading by the biosensing measurement system and performing corresponding measurements accordingly However, the existing coded information can only be identified by specific personnel (such as nursing staff and manufacturers). For home users, they can only trust the measuring device unilaterally, and cannot detect the coded information on the test piece at all. In this way, when the above-mentioned biosensing measurement system reads wrongly or misjudges, the patient is very likely to misestimate the need for blood glucose based on the wrong measurement data displayed by the blood glucose meter without knowing it. Supplementary insulin doses, or miscalculation of the amount of glucose that needs to be supplemented, all these situations cause great risks for patients.

On the other hand, in terms of the structural manufacturing level of the coded information of the test strips, the structure design of the existing test strips is usually to punch a plurality of holes on the back of the test strips, and then, the operator then uses the information of this batch of test strips , fill the holes at different positions with induction blocks, and the corresponding position of the measurement device must be equipped with an induction mechanism, so as to cooperate with the induction block on the test piece to achieve the purpose of identification of the measurement device; only this type of existing structure It has been found in actual use experience that because the processing quantity of the test piece is often quite large, in the aforementioned prior art, it is obviously a rather time-consuming and inefficient working method; moreover, because the holes of the test piece must have specific size, which will easily lead to serious problems such as a high defect rate of the test piece and difficulty in controlling the quality of the finished product, and it will easily cause troubles in the inspection of the product and make relevant personnel extremely troubled; There is a setting type for testing the coding information of the test piece, so the coding information and the setting area are actually quite limited. This may be a pity for the measurement capability of the measuring device, so the functional requirements of its measurement capability cannot be fully utilized. problems and shortcomings.

Contents of the invention

The purpose of the present invention is to provide a biosensing and measuring system with two-way verification of test strip information, which is suitable for measuring a sample.

The biosensing and measuring system of the present invention, which can bidirectionally check the test piece information, is suitable for measuring a sample; it includes: a detection test piece structure, and a measuring device;

The test piece structure includes:

A detection test strip, including a biosensing unit and a surface, the biosensing unit is used for sensing according to the sample and generating at least one reaction signal related to the sample; and

At least one identifiable character is arranged on the surface of the test strip and is related to the test piece information of the test strip; and

The measurement device includes an image capture unit, a test piece information acquisition unit, a user interface unit, a judgment unit, and a signal measurement unit, the image capture unit is used to capture an image corresponding to the character, The test piece information obtaining unit is used to obtain an obtained character according to the image, the user interface unit is used to output corresponding to the image and is used for the user to perform a related checking operation, and the judging unit is used to receive the corresponding During the checking operation, a check operation signal is checked and judgment is made based on it. When the judgment result of the judgment unit indicates that the test piece information is confirmed to be correct, the signal measurement unit is used to obtain a measurement result according to the acquired character and the response signal. .

In the biosensing measurement system of the present invention, the test strip information can be checked bidirectionally. The characters arranged on the surface of the detection test strip structure belong to at least one of a number form and a letter form; and the characters are in the form of the test strip code. related types.

The detection test piece structure of the biosensing measurement system whose test piece information can be double-checked in the present invention also includes at least one calibration character arranged on the surface of the detection test piece, the calibration character is related to the character, and the measuring device It also includes a correction code calculation unit, used to calculate a correction code according to the obtained characters, and the user interface unit is also used to output corresponding to the correction code for the user to perform the related checking operation.

The character set on the surface of the detection test strip structure of the biosensing measurement system of the present invention, which can bidirectionally check the test strip information, belongs to a combination of characters displayed on a multi-segment display.

Another object of the present invention is to provide a test strip structure.

The test piece structure of the present invention comprises:

A test strip, including a biosensing unit and a surface, the biosensing unit is used for sensing according to a sample and generating at least one reaction signal related to the sample; and

At least one identifiable character is arranged on the surface of the test strip and is related to the test piece information of the test strip.

The characters arranged on the surface of the detection test piece structure of the present invention belong to at least one of a number form and a letter form; and the characters are related to the test piece code.

The detection test strip structure of the present invention further includes at least one calibration character arranged on the surface of the detection test strip, and the calibration character is related to the character.

The character set on the surface of the test strip structure of the present invention belongs to a character combination displayed by a multi-segment display.

The beneficial effect of the present invention is that: by capturing the image corresponding to the character, outputting the image corresponding to the image, and allowing the user to perform the checking operation related to the test piece information, the test piece information can be made in The two-way confirmation between the user and the measuring device greatly reduces the probability of reading errors or misjudgments of the measuring device, and improves the accuracy of the measurement results. In this way, the identifiable character of the character can be used to provide the user with the purpose of two-way checking, and to achieve the benefit of simplifying the structure of the test strip.

Description of drawings

Fig. 1 is a schematic diagram illustrating a biosensing and measuring system in which test strip information can be checked bidirectionally according to a first preferred embodiment of the present invention;

Fig. 2 is a block diagram illustrating a test strip and a measuring device of the first preferred embodiment;

Fig. 3 is a flow chart illustrating a first operation process of a biological measurement method in which test strip information can be bidirectionally verified by the first preferred embodiment;

Fig. 4 is a flow chart illustrating a second operation process of the biological measurement method in which the test strip information can be bidirectionally verified by the first preferred embodiment;

Fig. 5 is a block diagram illustrating a second preferred embodiment of a biosensing measurement system in which test strip information of the present invention can be bidirectionally checked;

FIG. 6 is a flow chart illustrating a biological measurement method with two-way verification of test strip information implemented in the second preferred embodiment.

Detailed ways

In order to make the above objects, features and advantages of the present invention more comprehensible, specific implementations of the present invention will be described in detail below in conjunction with the accompanying drawings. First of all, it should be noted that the present invention is not limited to the following specific embodiments. Those skilled in the art should understand the present invention from the spirit embodied in the following embodiments, and each technical term can be optimized based on the spirit of the present invention. broad understanding. The same or similar components in the figures are denoted by the same reference numerals.

Please refer to Fig. 1 and Fig. 2, a first preferred embodiment of the biosensing measurement system 1 of the present invention, which can bidirectionally check the test strip information, includes a detection test strip structure 2 and a measuring device 3, the biosensing measurement The system 1 is suitable for measuring a sample (not shown), for example, for measuring glucose concentration, cholesterol concentration, etc. in blood.

The testing strip structure 2 includes a testing strip 20 and at least one identifiable character 221 . The test strip 20 includes a bio-sensing unit 21 and a surface 22 . The bio-sensing unit 21 is used for sensing according to the sample and generating at least one reaction signal related to the sample; the bio-sensing unit 21 is well known to those skilled in the art of the present invention, and is not The focus of the present invention, so its details are not repeated here. The character 221 is set on the surface 22, and is related to the coded information of the test piece 20 (for example, the type, batch number, etc.) of the test piece 20; it is worth mentioning that the so-called "has The meaning of "identification" means that the character 221 can be recognized by ordinary users (for example, patients in the home environment), and the character 221 belongs to at least one of a numerical digit form and a letter form , and the character 221 is related to the code of the test piece; it can be easily recognized by the user in the form of numbers or letters; in this first preferred embodiment, the character 221 belongs to a multi-segment display (for example, seven segments Display) can display a combination of characters, the combination of characters includes the characters in the form of numbers and the characters in the form of letters; the characters 221 are printed on the surface 22, but the characters 221 can also be in other ways ( For example, engraving) is disposed on the surface 22, and is not limited to the form disclosed in this preferred embodiment.

The measurement device 3 includes an image capture unit 31 , a test piece information acquisition unit 32 , a user interface unit 33 , a judgment unit 34 , and a signal measurement unit 35 . The image capturing unit 31 is used for capturing an image corresponding to the character 221 . The test piece information acquisition unit 32 is used to obtain an acquired character according to the image. The test piece information acquisition unit 32 includes an image pre-processing module 321 and a character recognition module 322 . The user interface unit 33 is used for output corresponding to the image and for the user to perform a related checking operation. In this first preferred embodiment, the user interface unit 33 includes an output module 331 (such as , a display, a speaker, or a combination thereof), and an input module 332 (for example, a button); however, the user interface unit 33 can also be a touch screen for the user to input information and output information to the user , not limited to the form disclosed in the first preferred embodiment. The judgment unit 34 is used for receiving a verification operation signal corresponding to the verification operation for judgment. When the judgment result of the judging unit 34 indicates that the test piece information is confirmed to be correct, the signal measuring unit 35 is used to obtain a measurement result according to the obtained character and the response signal; The slice information can be obtained correspondingly from the obtained characters; the processing performed by the signal measurement unit 35 is well known to those skilled in the art of the present invention, and is not the focus of the present invention, so details thereof will not be repeated here.

Corresponding to the above-mentioned first preferred embodiment, the steps performed by the measuring device 3 after the detection test strip structure 2 is inserted into the measuring device 3 will be further described below in conjunction with the biological measurement method of the present invention that can bidirectionally check the test piece information The biometric method in which the test piece information can be bidirectionally checked can be realized by the following two operation processes (first and second operation processes).

The first operation process

Please refer to FIG. 2 and FIG. 3 , the first operation flow of the biological measurement method with bidirectional verification of test strip information includes the following steps.

In step 401 , the image capture unit 31 captures an image corresponding to the character 221 disposed on the surface 22 .

For example, as shown in FIG. 2 , the surface 22 is provided with three characters 221 , namely "1", "2" and "3".

In step 402, the image pre-processing module 321 of the test piece information acquisition unit 32 pre-processes the image. The pre-processing performed by the image pre-processing module 321 includes image thresholding and image interference noise. Eliminate (image noise reduction).

In step 403 , the output module 331 of the user interface unit 33 displays the pre-processed image in step 402 for the user to perform a related checking operation through the input module 332 .

In step 404, the judging unit 34 receives a checking operation signal corresponding to the checking operation to judge; " matches with "the image displayed by the output module 331 that has undergone the pre-processing of step 402" (match), go to step 405 to continue processing; otherwise, go to step 407 to continue processing.

In step 405 , the character recognition module 322 of the test strip information obtaining unit 32 performs character recognition according to the pre-processed image in step 402 to obtain at least one obtained character.

Continuing the above example, as shown in FIG. 2 , the character recognition module 322 obtains three acquired characters respectively corresponding to the characters 221 , namely “1”, “2” and “3”.

In step 406, the signal measurement unit 35 obtains a measurement result according to the obtained character and at least one reaction signal related to the sample generated by the bio-sensing unit 21, and the output module 331 also outputs the measurement results.

In step 407, the output module 331 outputs a warning message to inform the user that "the test strip information may be wrong, please try again".

In the above-mentioned first operation process, by providing "the image that has been pre-processed" to the user, and allowing them to perform the related verification operation, the information of the test piece can be double-checked, not only by the measuring device 3. Perform measurement immediately after obtaining the unconfirmed test piece information, which can reduce the probability of reading error or misjudgment between the measuring device 3 and the detection test piece 20 .

Second operation process

Please refer to FIG. 2 and FIG. 4 , the second operation process of the biological measurement method with bidirectional verification of test strip information includes the following steps.

In step 501 , the image capturing unit 31 captures an image corresponding to the character 221 disposed on the surface 22 .

In step 502 , the image pre-processing module 321 of the test strip information obtaining unit 32 performs pre-processing on the image.

In step 503 , the character recognition module 322 of the test strip information obtaining unit 32 performs character recognition according to the pre-processed image in step 502 to obtain at least one obtained character.

In step 504 , the output module 331 of the user interface unit 33 outputs corresponding to the acquired character obtained from the image, and provides the user with a related checking operation through the input module 332 .

In this first preferred embodiment, the output module 331 is a multi-segment display for displaying the obtained character; however, the output module 331 can also be a speaker for playing the corresponding sound of the obtained character Sound; not limited to the form disclosed in the first preferred embodiment.

It is worth mentioning that assuming that the multi-segment display can represent m different characters, and assuming that the number of the characters 221 set on the surface 22 is k, then in the first preferred embodiment, through the surface The character 221 set by 22 can be combined with a number of code groups as high as m ^k groups. Compared with the prior art that uses "graphic elements formed by a specific structure" as a coding method, the code that can be combined in the present invention The number of groups is greatly increased, and the amount of information it can carry is also greatly increased.

In step 505, the judging unit 34 receives a checking operation signal corresponding to the checking operation to judge; When the identifiable character 221" matches "the obtained character"), proceed to step 506 for processing; otherwise, proceed to step 507 for processing.

In step 506, the signal measurement unit 35 obtains a measurement result according to the acquired character and at least one reaction signal related to the sample generated by the bio-sensing unit 21, and the output module 331 also outputs the measurement results.

In step 507, the output module 331 outputs a warning message to inform the user that "the test strip information may be wrong, please try again".

In the above-mentioned second operation process, by providing the "obtained character" to the user for the relevant checking operation, the test piece information can be bidirectionally checked.

Please refer to Fig. 5, a second preferred embodiment of the biosensing measurement system whose test strip information can be double-checked according to the present invention is similar to the first preferred embodiment, which includes a detection test strip structure 6 and a measuring device 7. In the following description, the details of elements similar to the first preferred embodiment will not be repeated.

The detection test piece structure 6 includes a detection test piece 60, the recognizable characters 221, and at least one calibration character 62; the detection test piece 60 includes the bio-sensing unit 21 and a surface 61; the characters 221 and The calibration character 62 is disposed on the surface 61 ; the calibration character 62 is related to the character 221 , for example, the calibration character 62 can be a checksum of the character 221 .

The measurement device 7 includes the image capture unit 31 , the test piece information acquisition unit 32 , the user interface unit 33 , the determination unit 34 , the signal measurement unit 35 , and a calibration code calculation unit 71 .

Corresponding to the above-mentioned second preferred embodiment, the steps performed by the measurement device 7 after the detection test strip 6 is inserted into the measurement device 7 will be further described below in conjunction with the biological measurement method of the present invention with two-way verification of test strip information.

Please refer to FIG. 5 and FIG. 6 , the biometric method for double-checking test strip information includes the following steps.

In step 801 , the image capture unit 31 captures an image corresponding to the character 221 disposed on the surface 61 .

In step 802 , the image pre-processing module 321 of the test strip information obtaining unit 32 performs pre-processing on the image.

In step 803 , the character recognition module 322 of the test strip information obtaining unit 32 performs character recognition according to the pre-processed image in step 802 to obtain at least one obtained character.

In step 804, the correction code calculating unit 71 calculates a correction code according to the obtained character.

For example, the character recognition module 322 obtains three obtained characters, which are "1", "2", and "3" respectively; the correction code calculation unit 71 calculates a correction code according to the obtained characters as "6" ".

In step 805 , the output module 331 of the user interface unit 33 outputs corresponding to the acquired character and the correction code, and provides the user with a related checking operation through the input module 332 . Continuing the above example, the output module 331 performs output corresponding to "1", "2", "3", and "6" (image display, or sound broadcast), and provides the user with the input module 332 for correlation The check operation.

In step 806, the judging unit 34 receives a checking operation signal corresponding to the checking operation to judge; " matches "the obtained character", and "the correction character 62 set on the surface 61" matches "the correction code"), proceed to step 807; otherwise, proceed to step 808.

In step 807, the signal measurement unit 35 is used to obtain a measurement result according to the acquired character and at least one response signal related to the sample generated by the bio-sensing unit 21, and the output module 331 also Output the measurement result.

In step 808, the output module 331 outputs a warning message to inform the user that "the test strip information may be wrong, please try again".

In the biological measurement method that can be bidirectionally verified corresponding to the above-mentioned test strip information, the "characters obtained" and "the correction code calculated by the correction code calculation unit 71" are provided to the user, and they are provided for the relevant The checking operation enables the test piece information and the calibration code to be double-checked, which can further reduce the probability of reading errors or misjudgments between the measuring device 7 and the testing test piece 6 .

Efficacy Description:

The fact that the effect of the present invention improves is as follows:

1. The main feature of the present invention is that the surface 22, 61 of the detection test piece 20, 60 is provided with a "recognizable" character 221, and the measuring device 3, 7 includes the image capture unit 31 for capturing Corresponding to the image of the character, and through the output module 331 corresponding to the innovative and unique type of output state, so that the present invention can be set on the surface 22, 61 through the character 221 and the existing technology mentioned in the background technology section. The characters output by the output module 331 are compared, so that the test piece information can be double-checked, so that ordinary users can easily perform comparison and identification, and the measurement work tends to be comprehensive and perfect. In this way, It can also ensure the correct measurement rate for ordinary home users, and greatly reduce the risk of measurement errors and the waste of test pieces caused by measurement failures.

2. From the perspective of product structure, the "recognizable" character 221 of the present invention is an innovative and unique structural composition design that is directly arranged on the surface 22, 61 of the test piece 20, 60, making the present invention contrast As far as the existing technology mentioned in the background technology section is concerned, it can completely improve the existing technical problems of using perforation, effectively improve the processing efficiency and reduce the process cost, and then achieve the practical progress and better industrial utilization of simplifying the structural benefits of the detection test piece. benefit.

The new effect that the present invention can produce is as follows:

The character 221 set on the surface 22, 61 of the detection test piece 20, 60 belongs to the structural design of the character combination displayed on the multi-segment display, which can greatly increase the number of coding groups, and the present invention can still provide the largest amount of information on the test piece. , to obtain the best measurement performance, and then enhance the product value and competitiveness for the industry to obtain better industrial economic benefits.

What has been described above is only a preferred embodiment of the present invention, and should not limit the scope of the present invention with this, that is, all simple equivalent changes and modifications made according to the claims of the present invention and the contents of the description of the invention still belong to this invention. within the scope of invention patents.

Claims (4)

1. the biological sensing measuring system that test piece information can two-wayly be checked, is applicable to measure a corpse or other object for laboratory examination and chemical testing; It is characterized in that it comprises: a test strip structure, and a measurement mechanism;

This test strip structure comprises:

One test strip, comprise a biological sensing cell and a surface, this biological sensing unit is in order to carry out sensing according to this corpse or other object for laboratory examination and chemical testing and to produce at least one reaction signal relevant to this corpse or other object for laboratory examination and chemical testing; And

At least one character with identifiability, is arranged at the surface of this test strip, and relevant to the test piece information of this test strip; And

This measurement mechanism comprises an image acquisition unit, one test piece information acquisition unit, one user's boundary element, one judging unit, and a signal measurement unit, this image acquisition unit corresponds to an image of this character in order to acquisition, this test piece information acquisition unit is in order to obtain a character obtained according to this image, this user's boundary element in order to carry out correspond to this image output and check operation with carry out being correlated with for user one, this judging unit corresponds to this and checks one of operation in order to receive and check operation signal judging according to this, when the judged result of this judging unit indicates this test piece validation of information errorless, this signal measurement unit obtains a measurement result in order to the character that obtains according to this and this reaction signal.

2. the biological sensing measuring system that can two-wayly check of test piece information as claimed in claim 1, is characterized in that: the character being arranged at this surface belong to a digital form and an alphabetical form at least one of them; This character is encoded to test piece in relevant kenel again.

3. the biological sensing measuring system that can two-wayly check of test piece information as claimed in claim 1 or 2, it is characterized in that: this test strip structure also comprises at least one correction character on this surface being arranged at this test strip, this correction character is relevant to this character, and this measurement mechanism also comprises a correcting code computing unit, character in order to obtain according to this calculates a correcting code, this user's boundary element also in order to carry out correspond to this correcting code output and check operation with this carrying out being correlated with for user.

4. the biological sensing measuring system that can two-wayly check of test piece information as claimed in claim 1 or 2, is characterized in that: this character being arranged at this surface belongs to the character combination shown by a multiple stage display.