CN103028205B - Utilize the therapy equipment of ultrasonic fat reduction transducer - Google Patents
Utilize the therapy equipment of ultrasonic fat reduction transducer Download PDFInfo
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- CN103028205B CN103028205B CN201110302700.2A CN201110302700A CN103028205B CN 103028205 B CN103028205 B CN 103028205B CN 201110302700 A CN201110302700 A CN 201110302700A CN 103028205 B CN103028205 B CN 103028205B
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Abstract
The invention provides a kind of Therapeutic Method and the device that utilize ultrasonic fat reduction transducer, belong to field of medical ultrasound treatment.Wherein, this utilizes the Therapeutic Method of ultrasonic fat reduction transducer, comprising: the treatment situation obtaining therapy area; According to the size at the convergence angle of described treatment situation determination ultrasonic fat reduction transducer; Adjust the running parameter of described ultrasonic fat reduction transducer, to obtain determined convergence angle.Technical scheme of the present invention can improve the efficiency for the treatment of under the prerequisite ensureing safety.
Description
Technical field
The present invention relates to field of medical ultrasound treatment, refer to a kind of Therapeutic Method and the device that utilize ultrasonic fat reduction transducer especially.
Background technology
As everyone knows, ultrasound wave and tissue interact and can produce some biological tissues effect.According to hyperacoustic local sound intensity height and sound wave radiation pattern, these biological tissue's effects can be divided into heat effect and non-thermomechanical effect.The absorption of heat effect phalangeal cell to ultrasonic energy is organized to cause it to be warming up to heat downright bad.Organize non-thermomechanical effect to refer to increase due to acoustic cavitation, acoustic streaming and the local cellular activity that causes of small amplitude motion so cellular morphology produced change, break, the phenomenon such as apoptosis.The physical factor affecting ultrasound biological organizational effect comprises sound field focusing form, frequency of sound wave, acoustic pressure amplitude, the continuous or factor such as pulse sound radiation pattern (pulse recurrence frequency and dutycycle), standing-wave condition, medium static pressure, temperature, viscid state and boundary condition.
In recent years, hyperacoustic biological tissue effect is subject to extensive investigation and application day by day at treatment ultrasound field.The application that high intensity ultrasound treatment melts at neoplastic fevers, external knock wave is pulverized in urinary stone, drug conveying, block nerves conduction etc. has new progress.
In fat-reducing and cosmetic applications field, ultrasound wave also manifests the advantage of its uniqueness, such as, adopt external low frequency ultrasound ripple to assist Wicresoft's liposuction procedures can strengthen local fat and destroy efficiency.The method and apparatus that the external transmitting high-intensity focusing ultrasonic wave of independent employing destroys regional adipose tissue experiences clinical verification, and manifests its curative effect, and its safety also obtains preliminary identification.This type for the treatment of is often first selected needs area for treatment, then External ultrasound transducers transmit ultrasonic waves is adopted to focus in subcutaneous layer of fat, based on hyperacoustic tissue heat effect or mechanical effect principle at current focal spot region destruction of adipose tissue, and pointwise move transducer change focal position cover needed for area for treatment.Under suitable area for treatment and dosage conditions, the fatty tissue of ultrasonic disruption is decomposed via the autologous metabolism cycle of human body.
Adopt the type of focusing significantly can promote hyperacoustic local focal sound intensity, and limit focal spot (-6dB focus sound intensity region) high sound intensity region in suitable scope, thus facility is accurately located in specific region and is produced desired ultrasonic wave tissue effect.In focus supersonic fat reducing treatment, avoid ultrasonic irradiation focal spot near sound field skin and/or focal spot far sound field, and focal spot radial periphery normal structure causes thermal burn and other damages to become an important clinical safety sex chromosome mosaicism being badly in need of solving.
Summary of the invention
The technical problem to be solved in the present invention is to provide a kind of Therapeutic Method and the device that utilize ultrasonic fat reduction transducer, can improve the efficiency of ultrasonic therapeutic under the prerequisite ensureing safety.
For solving the problems of the technologies described above, embodiments of the invention provide technical scheme as follows:
On the one hand, a kind of Therapeutic Method utilizing ultrasonic fat reduction transducer is provided, comprises:
Obtain the treatment situation of therapy area;
According to the size at the convergence angle of described treatment situation determination ultrasonic fat reduction transducer;
Adjust the running parameter of described ultrasonic fat reduction transducer, to obtain determined convergence angle.
Preferably, the treatment situation of described therapy area comprises the depth that the fat deposit thickness of therapy area and therapy target are positioned at fat deposit, and the treatment situation of described acquisition therapy area comprises:
A ultrasound wave burst pulse is launched to described therapy area;
Interval between the first ultrasonic echo that the interface layer obtaining coupling liquid and epidermis reflects and the second ultrasonic echo that interface layer that is fatty and muscle reflects;
Described interval to be multiplied by after the bulk sound velocity of fatty tissue divided by 2, to obtain the fat deposit thickness of described therapy area.
Preferably, the size at the described convergence angle according to described treatment situation determination ultrasonic fat reduction transducer comprises:
When the fat deposit thickness of described therapy area is greater than the first thickness or described therapy area is positioned at the intermediate depth position of fat deposit, determine that the convergence angle of ultrasonic fat reduction transducer is not more than 30 °;
When the fat deposit thickness of described therapy area is less than the second thickness or described therapy area is positioned at the shallow position, top layer of fat deposit, determine that the convergence angle of ultrasonic fat reduction transducer is not less than 30 °.
Preferably, the running parameter of the described ultrasonic fat reduction transducer of described adjustment, comprises to obtain determined convergence angle:
Adjust the focal length of described ultrasonic fat reduction transducer and the ratio in aperture, to obtain determined convergence angle.
Preferably, the running parameter of the described ultrasonic fat reduction transducer of described adjustment, also comprises to obtain determined convergence angle:
Adjust effective emission area of described ultrasonic fat reduction transducer, to obtain determined convergence angle.
The embodiment of the present invention additionally provides a kind of therapy equipment utilizing ultrasonic fat reduction transducer, comprising:
For obtaining the measurement module of the treatment situation of therapy area;
For the computing module of the size at the convergence angle according to described treatment situation determination ultrasonic fat reduction transducer;
For adjusting the parameter of described ultrasonic fat reduction transducer, to obtain the control module at determined convergence angle.
Preferably, described measurement module comprises:
For launching the transmitting submodule of a ultrasound wave burst pulse to described therapy area;
The measurement submodule of the interval between the second ultrasonic echo that the first ultrasonic echo reflected for the interface layer obtaining coupling liquid and epidermis and interface layer that is fatty and muscle reflect;
For described interval is multiplied by fatty tissue bulk sound velocity after divided by 2, obtain the acquisition submodule of the fat deposit thickness of described therapy area.
Preferably, described computing module comprises:
For when the fat deposit thickness of described therapy area is greater than the first thickness or described therapy area is positioned at the intermediate depth position of fat deposit, determine that the convergence angle of ultrasonic fat reduction transducer is not more than first calculating sub module of 30 °;
For when the fat deposit thickness of described therapy area is less than the second thickness or described therapy area is positioned at the shallow position, top layer of fat deposit, determine that the convergence angle of ultrasonic fat reduction transducer is not less than second calculating sub module of 30 °.
Preferably, described control module comprises:
For the ratio of the focal length and aperture that adjust described ultrasonic fat reduction transducer, control submodule with obtain determined convergence angle first.
Preferably, described control module also comprises:
For adjusting effective emission area of described ultrasonic fat reduction transducer, control submodule with obtain determined convergence angle second.
Embodiments of the invention have following beneficial effect:
In such scheme, first obtain the treatment situation of therapy area, according to the size at the convergence angle of the treatment situation determination ultrasonic fat reduction transducer of therapy area, adjust the running parameter of ultrasonic fat reduction transducer afterwards, to obtain determined convergence angle.The present invention can control the speed of the size in focusing spot region, the height of the focus sound intensity and focal spot sound intensity variable gradient by the size controlling to converge angle, thus while improving therapeutic efficiency, reduces ultrasonic irradiation to the thermal burn of near sound field skin, far sound field tissue and other radial periphery tissues and other risks damaged.
Accompanying drawing explanation
Fig. 1 is the schematic flow sheet utilizing the Therapeutic Method of ultrasonic fat reduction transducer of the embodiment of the present invention;
Fig. 2 is the structured flowchart utilizing the therapy equipment of ultrasonic fat reduction transducer of the embodiment of the present invention.
Detailed description of the invention
For embodiments of the invention will be solved technical problem, technical scheme and advantage clearly, be described in detail below in conjunction with the accompanying drawings and the specific embodiments.
Embodiments of the invention in prior art in focus supersonic fat reducing treatment, ultrasonic irradiation is near sound field skin and/or far sound field, and radial periphery normal structure can cause the problem of thermal burn and other damages, a kind of Therapeutic Method and the device that utilize ultrasonic fat reduction transducer are provided, the efficiency of ultrasonic therapeutic can be improved under the prerequisite ensureing safety.
Fig. 1 is the schematic flow sheet utilizing the Therapeutic Method of ultrasonic fat reduction transducer of the embodiment of the present invention, and as shown in Figure 1, the Therapeutic Method utilizing ultrasonic fat reduction transducer of the present embodiment, comprising:
Step 101: the treatment situation obtaining therapy area;
Step 102: according to the size at the convergence angle for the treatment of situation determination ultrasonic fat reduction transducer;
Step 103: the running parameter of adjustment ultrasonic fat reduction transducer, to obtain determined convergence angle.
The Therapeutic Method utilizing ultrasonic fat reduction transducer of the embodiment of the present invention, first the treatment situation of therapy area is obtained, according to the size at the convergence angle of the treatment situation determination ultrasonic fat reduction transducer of therapy area, adjust the running parameter of ultrasonic fat reduction transducer afterwards, to obtain determined convergence angle.The present invention can control the speed of the size in focusing spot region, the height of the focus sound intensity and focal spot sound intensity variable gradient by the size controlling to converge angle, thus while improving therapeutic efficiency, reduces ultrasonic irradiation to the thermal burn of near sound field skin, far sound field tissue and other radial periphery tissues and other risks damaged.
Below the Therapeutic Method of ultrasonic fat reduction transducer that utilizes of the present invention is described in detail.In focus supersonic fat reducing treatment, in order to reduce thermal burn that ultrasonic irradiation causes near sound field skin, far sound field tissue and other radial periphery tissues and other damages, need the size, the height of the focus sound intensity and the speed of focal spot sound intensity variable gradient that control focusing spot region.
In prior art, spherical surface focusing transducer is conventional high intensity focused ultrasound fat reduction transducer, is also one of several ultrasonic fat reduction transducer structures of focusing efficiency the best.Below just for spherical surface focusing transducer, illustrate and how to utilize ultrasonic fat reduction transducer to carry out ultrasonic fat reducing treatment.The focal spot of spherical surface focusing transducer is axially relevant with its convergence angle with lateral dimension, and the convergence angle of spherical surface focusing transducer is larger, and Voice segment is more concentrated, focal spot region is then less, focusing gain is larger, and the outside sound intensity variable gradient of focus is larger, is applicable to the meticulous treatment of single irradiation small size; Otherwise the convergence angle of spherical surface focusing transducer is less, then Voice segment is overstepping the bounds of propriety loose, and focal spot region is larger, and focusing gain is less, and the outside sound intensity variable gradient of focus is less, applicable single irradiation large volume fast treating.Therefore, can by controlling the convergence angle of spherical surface focusing transducer to realize controlling size, the height of the focus sound intensity and the speed of focal spot sound intensity variable gradient in focusing spot region.The Therapeutic Method of ultrasonic fat reduction transducer that utilizes of the present invention comprises the following steps:
Step S1: the treatment situation obtaining therapy area;
Before carrying out ultrasonic fat reducing treatment, first obtain the treatment situation of therapy area, to determine required convergence angle according to treatment situation.Ultrasonic fat reduction transducer acoustic wave propagation path order comprises epidermis and skin corium (epidermis), subcutaneous layer of fat (fat), muscle and connective tissue (muscle).The treatment situation obtained comprises the depth that the fat deposit thickness at therapy area place and therapy area are positioned at fat deposit, particularly, the fat deposit thickness obtaining therapy area place can step realize by the following method: launch a ultrasound wave burst pulse to therapy area; Interval between the first ultrasonic echo that the interface layer obtaining coupling liquid and epidermis reflects and the second ultrasonic echo that interface layer that is fatty and muscle reflects; Interval is multiplied by divided by 2 after the bulk sound velocity of fatty tissue, the fat deposit thickness of the target area that obtains medical treatment.But the fat deposit thickness realizing obtaining therapy area place is not limited to said method, skinfold kind of calliper, CT (computedtomography can also be passed through, CT) mode such as/MRI (MagneticResonanceImaging, nuclear magnetic resonance) radiographic measurement realizes;
Step S2: determine the size converging angle according to the treatment situation of therapy area;
After the fat deposit thickness of the target region that obtains medical treatment and therapy area are positioned at the depth of fat deposit, just can determine a suitable convergence angle angle.Adopt and converge greatly the rapid change that angle (30-180 degree) can make the focusing sound intensity of ultrasonic fat reduction transducer acquisition sufficient intensity, meticulous focal spot region and focal spot region sound intensity gradient.Under short pulse radiation parameter, also help and obtain the enough cavitation threshold sound intensity by less electrical power, and sound intensity variable gradient larger in focal spot region, the mechanical cavitation effect of suitable accurate excite tissue; Under continuous irradiation condition, more promptly, and accurately can control the hot necrotic zone size in focal spot region and reduce the downright bad risk of focal spot peripheral organization heat.In sum, large position and the size converging angle and contribute to accurately controlling to organize destroyed area, and the treatment of superficial tissue is particularly suitable for due to its characteristic sharply focused on.
The determination of converging angle size and ultrasonic fat reduction transducer operating frequency, focal position are relevant with fat deposit thickness.Illustrate: for concludeing a contract or treaty the fat deposit thickness of 20 millimeters, wish that limiting spherical surface focusing transducers focus sound field-6dB focal spot is less than 20 millimeters along the axial major diameter of sound and suitably leaves the safe distance (such as-6dB major diameter is 10 millimeters, and ultrasonic fat reduction transducer focus is positioned at fat deposit centre position) of far and near field.Under selected operating frequency, the ratio square that-6dB major diameter of this ultrasonic fat reduction transducer is about ultrasonic fat reduction transducer focal length and aperture is multiplied by 7 times of operation wavelengths.Therefore, after determine required focusing acoustic field-6dB major diameter numerical value according to fat deposit thickness, also just determine the ratio in focal length needed for this ultrasonic fat reduction transducer and aperture.And namely the half value of the ratio of Sphere focusing supersonic fat reduction transducer aperture and focal length equals the sine function at half convergence angle, can determine according to ultrasonic fat reduction transducer operating frequency, focal position and fat deposit thickness the size converging angle thus.
Above-mentioned example only provides a kind of guideline determining to converge angle size, in actual use, by industry those of ordinary skill, can adjust the size converging angle according to this principle depending on practical situation flexibly.Its convergence angle of the focus supersonic fat reduction transducer of normally used meticulous strong-focusing characteristic is all greater than 30 degree.Therefore, focal position that is thinner at fat deposit or single ultrasonic irradiation be positioned at the shallow table of fat deposit (such as the distance on distance fat deposit surface is less than 1/3rd of fat deposit thickness for the shallow table of fat deposit) or close to muscle and connective tissue interface time, larger convergence angle can be adopted, such as be not less than the convergence angle of 30 degree, to ensure Therapeutic safety.At fat deposit thicker and the focal position of single ultrasonic irradiation is positioned at fat deposit intermediate depth position time, less convergence angle can be adopted, such as be not more than the convergence angle of 30 degree, to realize single large volume fast treating under the prerequisite ensureing focus far field and near field safety;
Step S3: the parameter of adjustment spherical surface focusing transducer, to obtain determined convergence angle.
For spherical surface focusing transducer, the scope of the focal length of spherical surface focusing transducer and the ratio in aperture is between 0.5 (now spherical surface focusing transducer is hemisphere transducer) extremely infinitely great (now spherical surface focusing transducer is plane non-geometric focused transducer), the ratio of focal length and aperture half value (ultrasonic fat reduction transducer radius) is the sine function at half convergence angle, the ratio in focal length and aperture is larger, focus on convergence angle less, otherwise, the ratio in focal length and aperture is less, then focus on convergence angle larger.Therefore, the focal length of adjustment spherical surface focusing transducer and the ratio in aperture can be passed through, control to focus on the size converging angle.In concrete enforcement, several mode can be had to obtain suitable convergence angle, such as, fix the focal length of spherical surface focusing transducer, the pore size of adjustment spherical surface focusing transducer; Or change the focal length length of spherical surface focusing transducer, the pore size of fixing spherical surface focusing transducer; Or adjust the focal length length of spherical surface focusing transducer and pore size obtains different focal lengths and aperture ratio simultaneously, change and converge angle size.In sum, suitable spherical surface focusing transducer focal length (0.5-12 centimetre), aperture (0.5-20 centimetre) can be selected, to obtain the convergence angle determined.
Further, when focal length length and pore size are fixed, trickle adjustment can also be carried out by the effective emission area changing spherical surface focusing transducer to convergence angle.Because the effective emission area changing spherical surface focusing transducer can change the equivalent transmitting aperture of spherical surface focusing transducer, be thus equal to the ratio changing focal length and aperture.Particularly, can on the spherical surface focusing transducer surface of emission borehole to reduce effective emission area, thus to convergence angle carry out trickle adjustment.The bore region dug out can be used for placing other monitoring sensors or treatment emitter, or arranges the coupling cooling water channel etc. of transducer.In addition, coordinate the mode (such as polycyclic electrode) of multi-electrode local excitation piezoelectric, the subregion transmitting of whole spherical surface focusing transducer can be controlled and other regions are not launched, and then convergence angle can be finely tuned in real time.
Not limiting to for spherical surface focusing transducer above by changing the method converging angle adjustment focal spot size and focusing gain, other non-spherical crown focused transducer structures can also be applied to.Such as cylindrical focusing transducer, the different focus characteristics converging angle can be constructed by the size changing its focusing surface; For the transducer of acoustic lens structure, the size converging angle can be changed by the curvature changing its lens; For multi-transducer array, the relative delay (phase contrast) of relative position or excitation signal between adjustment transducer can be passed through, to construct the focus characteristics that different equivalent converges angle.
Fig. 2 is the structured flowchart utilizing the therapy equipment of ultrasonic fat reduction transducer of the embodiment of the present invention, and as shown in Figure 2, the present embodiment comprises:
For obtaining the measurement module 20 of the treatment situation of therapy area;
For the computing module 22 of the size at the convergence angle according to treatment situation determination ultrasonic fat reduction transducer;
For adjusting the parameter of ultrasonic fat reduction transducer, to obtain the control module 24 at determined convergence angle.
Preferably, measurement module 20 comprises:
For launching the transmitting submodule of a ultrasound wave burst pulse to therapy area;
The measurement submodule of the interval between the second ultrasonic echo that the first ultrasonic echo reflected for the interface layer obtaining coupling liquid and epidermis and interface layer that is fatty and muscle reflect;
For interval is multiplied by fatty tissue bulk sound velocity after divided by 2, the acquisition submodule of the fat deposit thickness of the target area that obtains medical treatment.
Preferably, computing module 22 comprises:
For when the fat deposit thickness of therapy area is greater than the first thickness or therapy area is positioned at the intermediate depth position of fat deposit, determine that the convergence angle of ultrasonic fat reduction transducer is not more than first calculating sub module of 30 °;
For when the fat deposit thickness of therapy area is less than the second thickness or therapy area is positioned at the shallow position, top layer of fat deposit, determine that the convergence angle of ultrasonic fat reduction transducer is not less than second calculating sub module of 30 °.
Preferably, control module 24 comprises:
For the ratio of the focal length and aperture that adjust ultrasonic fat reduction transducer, control submodule with obtain determined convergence angle first.
Preferably, control module 24 also comprises:
For adjusting effective emission area of ultrasonic fat reduction transducer, control submodule with obtain determined convergence angle second.
The therapy equipment utilizing ultrasonic fat reduction transducer of the embodiment of the present invention, first the treatment situation of therapy area is obtained, according to the size at the convergence angle of the treatment situation determination ultrasonic fat reduction transducer of therapy area, adjust the running parameter of ultrasonic fat reduction transducer afterwards, to obtain determined convergence angle.The present invention can control the speed of the size in focusing spot region, the height of the focus sound intensity and focal spot sound intensity variable gradient by the size controlling to converge angle, thus while improving therapeutic efficiency, reduces ultrasonic irradiation to the thermal burn of near sound field skin, far sound field tissue and other radial periphery tissues and other risks damaged.
In each embodiment of the method for the present invention; the sequence number of described each step can not be used for the sequencing limiting each step; for those of ordinary skill in the art, under the prerequisite not paying creative work, the priority of each step is changed also within protection scope of the present invention.
The above is the preferred embodiment of the present invention; it should be pointed out that for those skilled in the art, under the prerequisite not departing from principle of the present invention; can also make some improvements and modifications, these improvements and modifications also should be considered as protection scope of the present invention.
Claims (4)
1. utilize a therapy equipment for ultrasonic fat reduction transducer, it is characterized in that, comprising:
For obtaining the measurement module of the treatment situation of therapy area, wherein, treatment situation comprises the depth that the fat deposit thickness of therapy area and therapy area are positioned at fat deposit;
For the computing module of the size at the convergence angle according to described treatment situation determination ultrasonic fat reduction transducer;
For adjusting the parameter of described ultrasonic fat reduction transducer, to obtain the control module at determined convergence angle;
Wherein, described computing module comprises:
For when the fat deposit thickness of described therapy area is greater than the first thickness or described therapy area is positioned at the intermediate depth position of fat deposit, determine that the convergence angle of ultrasonic fat reduction transducer is not more than first calculating sub module of 30 °;
For when the fat deposit thickness of described therapy area is less than the second thickness or described therapy area is positioned at the shallow position, top layer of fat deposit, determine that the convergence angle of ultrasonic fat reduction transducer is not less than second calculating sub module of 30 °.
2. the therapy equipment utilizing ultrasonic fat reduction transducer according to claim 1, is characterized in that, described measurement module comprises:
For launching the transmitting submodule of a ultrasound wave burst pulse to described therapy area;
The measurement submodule of the interval between the second ultrasonic echo that the first ultrasonic echo reflected for the interface layer obtaining coupling liquid and epidermis and interface layer that is fatty and muscle reflect;
For described interval is multiplied by fatty tissue bulk sound velocity after divided by 2, obtain the acquisition submodule of the fat deposit thickness of described therapy area.
3. the therapy equipment utilizing ultrasonic fat reduction transducer according to claim 1, is characterized in that, described control module comprises:
For the ratio of the focal length and aperture that adjust described ultrasonic fat reduction transducer, control submodule with obtain determined convergence angle first.
4. the therapy equipment utilizing ultrasonic fat reduction transducer according to claim 1, is characterized in that, described control module also comprises:
For adjusting effective emission area of described ultrasonic fat reduction transducer, control submodule with obtain determined convergence angle second.
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| US20100036246A1 (en) * | 2008-08-07 | 2010-02-11 | Leonid Kushculey | Automatic fat thickness measurements |
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