CN103005261B - Diet supplement capable of restraining diabetic patient's blood sugar level from increasing after meal - Google Patents
Diet supplement capable of restraining diabetic patient's blood sugar level from increasing after meal Download PDFInfo
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Abstract
Description
技术领域 technical field
本发明涉及保健食品技术领域，涉及针对糖尿病患者的膳食补充剂，具体地涉及一种可抑制糖尿病患者餐后血糖升高的膳食补充剂。The invention relates to the technical field of health food, and relates to a dietary supplement for diabetic patients, in particular to a dietary supplement capable of inhibiting postprandial blood sugar rise in diabetic patients.
背景技术 Background technique
2007-08年，在中华医学会糖尿病学分会组织下，在全国14个省市进行了糖尿病的流行病学调查。通过加权分析，在考虑性别、年龄、城乡分布和地区差别的因素后，估计我国20岁以上的成年人中糖尿病患病率为9.7%，我国的成人糖尿病患总数达9240万，其中农村4310万，城市4930万左右。并且这些数字还在逐年增加，我国可能已经成为世界上糖尿病患病人数最多的国家。我国糖尿病流行病学的一个显著特点是空腹血糖正常、餐后血糖高者在糖尿病人群中所占比例高，在新诊断的糖尿病患中单纯餐后血糖升高者占近50%，并且注射胰岛素也难以控制。From 2007 to 2008, under the organization of Diabetes Society of Chinese Medical Association, an epidemiological survey of diabetes was carried out in 14 provinces and cities across the country. Through weighted analysis, after considering factors such as gender, age, urban-rural distribution and regional differences, it is estimated that the prevalence of diabetes among adults over 20 years old in my country is 9.7%, and the total number of adult diabetic patients in my country reaches 92.4 million, of which 43.1 million are in rural areas , the city is about 49.3 million. And these numbers are still increasing year by year, and my country may have become the country with the largest number of diabetic patients in the world. A notable feature of the epidemiology of diabetes in my country is that people with normal fasting blood sugar and high postprandial blood sugar account for a high proportion of the diabetic population. Among newly diagnosed diabetic patients, those with elevated postprandial blood sugar account for nearly 50%, and insulin injections Also difficult to control.
目前控制餐后血糖水平升高的手段主要有药物治疗和饮食控制两大类。药物治疗常用的有格列奈类药物和α-糖苷酶抑制剂，前者通过刺激胰岛素的早期分泌而降低餐后血糖，常见的副作用有低血糖和体重增加；后者通过抑制碳水化合物在小肠上部的吸收而降低餐后血糖，常见的副作用为胃肠道反应。药物治疗由于高昂的价格以及众所周知的毒副作用，不能作为控制餐后血糖的长久之计。食疗主要是通过进食膳食纤维含量丰富的低脂肪低能量食物，来延长食物在胃中的排空时间，增加饱腹感，既限制脂肪和碳水化合物的摄入，又影响葡萄糖的消化与吸收，从而改善餐后血糖水平。例如目前市面上常见的高纤饼干、高纤糕点、复合谷物营养餐、糖尿病专用面条等，均用具有高纤维素含量的食品来替代糖尿病患者的正餐来实现对于餐后血糖水平的控制。但是上述食品多选用不溶性膳食纤维，饱腹感强而维生素和矿物质的含量低，食用后影响其它饮食，限制了饮食的多样性及多种营养成分的摄入，同时口味单一、口感较差，长期食用不仅难以下咽，亦会营养失衡。开发一种服用量小而延缓糖尿病患者餐后血糖升高效果显著的膳食补充剂将具有极大的市场前景。At present, the means of controlling postprandial blood glucose level mainly include drug therapy and diet control. Medications commonly used include glinides and α-glucosidase inhibitors. The former reduces postprandial blood sugar by stimulating the early secretion of insulin, and common side effects include hypoglycemia and weight gain; the latter inhibits the flow of carbohydrates in the upper small intestine. The absorption reduces postprandial blood sugar, and the common side effect is gastrointestinal reactions. Drug therapy cannot be used as a long-term solution to control postprandial blood sugar due to its high price and well-known toxic side effects. Diet therapy is mainly to prolong the emptying time of food in the stomach and increase the feeling of fullness by eating low-fat and low-energy foods rich in dietary fiber, which not only limits the intake of fat and carbohydrates, but also affects the digestion and absorption of glucose. This improves postprandial blood sugar levels. For example, high-fiber biscuits, high-fiber cakes, compound grain nutritional meals, and special noodles for diabetes, which are common in the market at present, all use foods with high fiber content to replace the main meals of diabetic patients to achieve postprandial blood sugar control. However, the above-mentioned foods mostly use insoluble dietary fiber, which has a strong sense of satiety and low vitamin and mineral content. After eating, it affects other diets, limits the diversity of the diet and the intake of multiple nutrients, and has a single taste and poor mouthfeel. , Long-term consumption is not only difficult to swallow, but also causes nutritional imbalance. It will have a great market prospect to develop a dietary supplement that has a small dosage and has a significant effect in delaying the postprandial blood sugar rise of diabetic patients.
CN 101496580A提供了一种供糖尿病患者食用含短肽的特殊膳食用食品的配方，该食品以食源性短肽为主要原料，添加山药、桑叶、葛根、黄精、玉米须、茯苓、乌梅、玉竹等药食两用中草药提取物，再辅以低聚糖、维生素和矿物质，组成复合配方。该配方的食品可以辅助降血糖和控制糖尿病患者血糖水平，为机体提供优质氮源，补充人体必需的多种维生素和矿物质，改善糖尿病患者的营养状况，预防糖尿病并发症的发生，提高机体免疫力。缺点是配方复杂，成本较高，且影响正常饮食。CN 101496580A provides a formula for diabetic patients to eat special dietary food containing short peptides. The food uses food-derived short peptides as the main raw material, and adds yam, mulberry leaves, kudzu root, sealwort, corn silk, poria cocos, black plum, Polygonatum and other medicinal and edible Chinese herbal extracts are supplemented with oligosaccharides, vitamins and minerals to form a compound formula. The food with this formula can help lower blood sugar and control the blood sugar level of diabetic patients, provide high-quality nitrogen source for the body, supplement various vitamins and minerals necessary for the human body, improve the nutritional status of diabetic patients, prevent the occurrence of diabetic complications, and improve the body's immunity force. The disadvantage is that the formula is complicated, the cost is high, and it affects the normal diet.
发明内容 Contents of the invention
本发明目的在于针对现有技术的不足，提供一种可抑制糖尿病患者餐后血糖升高的膳食补充剂，其服用量小，效果明显，在不影响正常饮食的前提下可显著抑制糖尿病患者餐后血糖升高。The purpose of the present invention is to address the deficiencies in the prior art, and provide a dietary supplement that can inhibit the postprandial blood sugar rise of diabetic patients. Blood sugar rises afterwards.
为达到上述目的，本发明采用如下技术方案：To achieve the above object, the present invention adopts the following technical solutions:
一种可抑制糖尿病患者餐后血糖升高的膳食补充剂，包括如下重量百分比的组分：不消化性碳水化合物8wt%-97wt%、食品胶1wt%-10wt%、低血糖生成指数的糖类1wt%-90wt%、调味剂1wt%-80wt%。A dietary supplement capable of inhibiting postprandial blood sugar rise in diabetic patients, comprising the following components by weight percentage: 8wt%-97wt% of indigestible carbohydrates, 1wt%-10wt% of food gum, sugars with low glycemic index 1wt%-90wt%, flavoring agent 1wt%-80wt%.
本发明所述的不消化性碳水化合物优选为聚葡萄糖、抗性淀粉、抗性糊精、菊粉中的一种或至少两种的组合；特别优选为聚葡萄糖。所述的聚葡萄糖即水溶性膳食纤维，其可调节脂类代谢，限制消化道内脂肪的吸收、促进类脂化合物的排泄、增加饱腹感；吸附胆汁酸、胆固醇变异原等有机分子，抑制总胆固醇（TC）浓度升高，降低胆酸及盐类的合成与吸收，降低人体血浆和肝脏胆固醇水平；阻碍食物与消化液充分接触，抑制增血糖素分泌，促使葡萄糖吸收减慢，从而降低餐后血糖水平，同时又能防止低血糖的发生。所述的抗性淀粉在体内消化缓慢、吸收和进入血液均较为缓慢，具有类似水溶性膳食纤维的性质。所述的抗性糊精本质上为一种低热量的聚葡萄糖。所述的菊粉为天然果聚糖的混合物，具有调节血脂、降低血糖、促进矿物质吸收以及防治便秘之功效。The indigestible carbohydrate of the present invention is preferably one or a combination of at least two of polydextrose, resistant starch, resistant dextrin and inulin; particularly preferably polydextrose. The polydextrose is a water-soluble dietary fiber, which can regulate lipid metabolism, limit the absorption of fat in the digestive tract, promote the excretion of lipid compounds, and increase satiety; absorb organic molecules such as bile acids and cholesterol variants, and inhibit total Elevated cholesterol (TC) concentration reduces the synthesis and absorption of bile acids and salts, lowers plasma and liver cholesterol levels; prevents full contact between food and digestive juices, inhibits glucagon secretion, and slows down glucose absorption, thereby reducing meal intake. After the blood sugar level, but also to prevent the occurrence of hypoglycemia. The resistant starch is digested slowly in the body, absorbed slowly and enters the blood, and has properties similar to water-soluble dietary fiber. The resistant dextrin is essentially a low-calorie polydextrose. The inulin is a mixture of natural fructans, which has the effects of regulating blood fat, lowering blood sugar, promoting mineral absorption and preventing constipation.
所述不消化性碳水化合物在本发明所述的膳食补充剂中的重量百分比为8wt%-97wt%，例如可以是8wt%-43.7wt%、25wt%-64.5wt%、54.1wt%-97wt%、8wt%、10wt%、12.3wt%、15wt%、20wt%、26.8wt%、30wt%、31.7wt%、35wt%、40wt%、45wt%、50wt%、55wt%、58.2wt%、60wt%、62.3wt%、65wt%、70wt%、71.9wt%、75wt%、80wt%、85wt%、90wt%、93wt%、95wt%、96.5wt%、97wt%；优选为30wt%-80wt%；更优选为50wt%-70wt%。The weight percentage of the indigestible carbohydrate in the dietary supplement of the present invention is 8wt%-97wt%, such as 8wt%-43.7wt%, 25wt%-64.5wt%, 54.1wt%-97wt% , 8wt%, 10wt%, 12.3wt%, 15wt%, 20wt%, 26.8wt%, 30wt%, 31.7wt%, 35wt%, 40wt%, 45wt%, 50wt%, 55wt%, 58.2wt%, 60wt%, 62.3wt%, 65wt%, 70wt%, 71.9wt%, 75wt%, 80wt%, 85wt%, 90wt%, 93wt%, 95wt%, 96.5wt%, 97wt%; preferably 30wt%-80wt%; more preferably 50wt%-70wt%.
本发明所述的食品胶包括果胶、树胶、豆胶、藻胶以及其他种类可食用的生物胶。所述果胶例如苹果果胶、柚皮果胶、蓝莓果胶、菠萝果胶等，所述树胶阿拉伯树胶、黄蓍胶、桃胶等，所述豆胶例如瓜尔豆胶、槐豆胶、葫芦巴胶、决明胶等，所述藻胶例如琼胶、褐藻胶等，所述其他种类可食用的生物胶例如黄原胶、魔芋胶、黄蜀葵胶等。所述的食品胶优选果胶、瓜尔豆胶、黄原胶、魔芋胶、葫芦巴胶、槐豆胶、黄蜀葵胶、决明胶中的一种或至少两种的组合；特别优选果胶。所述的食品胶在胃肠道遇水后能够与葡萄糖形成粘胶，从而减慢糖的吸收，使餐后血糖和胰岛素的水平降低，并具有降低胆固醇的作用。The food gum described in the present invention includes pectin, gum, bean gum, alginate gum and other types of edible bio-glue. The pectin such as apple pectin, pomelo pectin, blueberry pectin, pineapple pectin, etc., the gum arabic, tragacanth gum, peach gum, etc., the bean gum such as guar gum, locust bean gum , fenugreek gum, cassia gum, etc., the alginate such as agar gum, alginate, etc., the other types of edible biological gums such as xanthan gum, konjac gum, marshmallow gum, etc. The food gum is preferably one or a combination of at least two of pectin, guar gum, xanthan gum, konjac gum, fenugreek gum, locust bean gum, marshmallow gum, and cassia gum; pectin is particularly preferred. The food glue can form viscose with glucose after meeting water in the gastrointestinal tract, thereby slowing down the absorption of sugar, lowering the levels of blood sugar and insulin after meals, and having the effect of lowering cholesterol.
所述食品胶在本发明所述的膳食补充剂中的重量百分比为1wt%-10wt%，例如可以是1wt%-3.7wt%、5wt%-8.5wt%、4.1wt%-10wt%、1wt%、1.5wt%、2wt%、2.2wt%、2.5wt%、2.9wt%、3wt%、3.17wt%、3.5wt%、4wt%、4.21wt%、4.5wt%、4.68wt%、5wt%、5.3wt%、5.9wt%、6wt%、6.5wt%、6.6wt%、7wt%、7.5wt%、8wt%、8.41wt%、9wt%、9.3wt%、9.8wt%、10wt%；优选为2wt%-8wt%；更优选为4wt%-6wt%。The weight percentage of the food gum in the dietary supplement of the present invention is 1wt%-10wt%, such as 1wt%-3.7wt%, 5wt%-8.5wt%, 4.1wt%-10wt%, 1wt% , 1.5wt%, 2wt%, 2.2wt%, 2.5wt%, 2.9wt%, 3wt%, 3.17wt%, 3.5wt%, 4wt%, 4.21wt%, 4.5wt%, 4.68wt%, 5wt%, 5.3 wt%, 5.9wt%, 6wt%, 6.5wt%, 6.6wt%, 7wt%, 7.5wt%, 8wt%, 8.41wt%, 9wt%, 9.3wt%, 9.8wt%, 10wt%; preferably 2wt% -8wt%; more preferably 4wt%-6wt%.
本发明所述的低血糖生成指数的糖类是指血糖生成指数（GI）在55以下的糖类，包括单糖和/或糖醇。所述单糖例如葡萄糖、果糖、半乳糖、核糖、脱氧核糖等。所述糖醇例如异麦芽酮糖醇、木糖醇、赤藓糖醇、甘露糖醇、山梨糖醇、麦芽糖醇、乳糖醇等。所述的低血糖生成指数的糖类优选异麦芽酮糖醇、果糖、木糖醇、赤藓糖醇、甘露糖醇、山梨糖醇；特别优选异麦芽酮糖醇。所述的低血糖生成指数的糖类对人体血糖值的上升无影响或无显著影响，且能为糖尿病患者提供一定热量。The sugars with a low glycemic index in the present invention refer to sugars with a glycemic index (GI) below 55, including monosaccharides and/or sugar alcohols. The monosaccharides are, for example, glucose, fructose, galactose, ribose, deoxyribose and the like. The sugar alcohols are, for example, isomalt, xylitol, erythritol, mannitol, sorbitol, maltitol, lactitol and the like. The sugars with low glycemic index are preferably isomalt, fructose, xylitol, erythritol, mannitol, sorbitol; particularly preferably isomalt. The sugars with a low glycemic index have no or no significant effect on the rise of blood sugar in the human body, and can provide certain calories for diabetic patients.
所述低血糖生成指数的糖类在本发明所述的膳食补充剂中的重量百分比为1wt%-90wt%，例如可以是1wt%-33.1wt%、25wt%-74.5wt%、44.1wt%-90wt%、1wt%、3wt%、5wt%、7.5wt%、9wt%、10wt%、12.3wt%、15wt%、20wt%、26.8wt%、30wt%、31.7wt%、35wt%、40wt%、45wt%、50wt%、55wt%、58.2wt%、60wt%、62.3wt%、65wt%、70wt%、71.9wt%、75wt%、80wt%、85wt%、90wt%；优选为10wt%-60wt%；更优选为15wt%-40wt%。The weight percentage of the carbohydrates with low glycemic index in the dietary supplement of the present invention is 1wt%-90wt%, such as 1wt%-33.1wt%, 25wt%-74.5wt%, 44.1wt%- 90wt%, 1wt%, 3wt%, 5wt%, 7.5wt%, 9wt%, 10wt%, 12.3wt%, 15wt%, 20wt%, 26.8wt%, 30wt%, 31.7wt%, 35wt%, 40wt%, 45wt% %, 50wt%, 55wt%, 58.2wt%, 60wt%, 62.3wt%, 65wt%, 70wt%, 71.9wt%, 75wt%, 80wt%, 85wt%, 90wt%; preferably 10wt%-60wt%; more Preferably it is 15wt%-40wt%.
本发明所述的调味剂可以为任何一种能够改善感官性与口感的食品调味剂，例如天然植物成分、合成香精、咸味剂、甜味剂、鲜味剂、酸味剂、辛香剂等等，其中优选具有营养价值的天然植物成分以及可增进食欲又有助于钙、磷等营养物质消化吸收的酸味剂。所述天然植物成分例如绿茶粉、红枣粉、苹果粉、柠檬粉、橘子粉、香蕉粉、山药粉等；特别优选绿茶粉。所述酸味剂例如柠檬酸、碳酸氢钠、碳酸氢钾等；特别优选柠檬酸。The flavoring agent described in the present invention can be any food flavoring agent that can improve sensory properties and mouthfeel, such as natural plant ingredients, synthetic essences, salty flavoring agents, sweeteners, umami flavoring agents, sour flavoring agents, spices, etc. etc. Among them, natural plant ingredients with nutritional value and sour agents that can increase appetite and help the digestion and absorption of nutrients such as calcium and phosphorus are preferred. The natural plant ingredients are such as green tea powder, red date powder, apple powder, lemon powder, orange powder, banana powder, yam powder, etc.; green tea powder is particularly preferred. The sour agent such as citric acid, sodium bicarbonate, potassium bicarbonate, etc.; particularly preferably citric acid.
所述调味剂在本发明所述的膳食补充剂中的重量百分比为1wt%-80wt%，例如可以是1wt%-53.1wt%、15wt%-64.5wt%、34.1wt%-80wt%、1wt%、3wt%、5wt%、7.5wt%、9wt%、10wt%、12.3wt%、15wt%、20wt%、26.8wt%、30wt%、31.7wt%、35wt%、40wt%、45wt%、50wt%、55wt%、58.2wt%、60wt%、62.3wt%、65wt%、70wt%、71.9wt%、75wt%、78.6wt%、80wt%；优选为5wt%-50wt%；更优选为10wt%-30wt%。The weight percentage of the flavoring agent in the dietary supplement of the present invention is 1wt%-80wt%, such as 1wt%-53.1wt%, 15wt%-64.5wt%, 34.1wt%-80wt%, 1wt% , 3wt%, 5wt%, 7.5wt%, 9wt%, 10wt%, 12.3wt%, 15wt%, 20wt%, 26.8wt%, 30wt%, 31.7wt%, 35wt%, 40wt%, 45wt%, 50wt%, 55wt%, 58.2wt%, 60wt%, 62.3wt%, 65wt%, 70wt%, 71.9wt%, 75wt%, 78.6wt%, 80wt%; preferably 5wt%-50wt%; more preferably 10wt%-30wt% .
优选地，本发明的所述的膳食补充剂如下：Preferably, the dietary supplement of the present invention is as follows:
一种可抑制糖尿病患者餐后血糖升高的膳食补充剂，包括如下重量百分比的组分：不消化性碳水化合物30wt%-80wt%、食品胶2wt%-8wt%、低血糖生成指数的糖类10wt%-60wt%、调味剂5wt%-50wt%。A dietary supplement capable of inhibiting postprandial blood sugar rise in diabetic patients, comprising the following components by weight percentage: 30wt%-80wt% indigestible carbohydrates, 2wt%-8wt% food gum, sugars with low glycemic index 10wt%-60wt%, flavoring agent 5wt%-50wt%.
进一步优选地，本发明的所述的膳食补充剂如下：Further preferably, the dietary supplement of the present invention is as follows:
一种可抑制糖尿病患者餐后血糖升高的膳食补充剂，包括如下重量百分比的组分：聚葡萄糖50wt%-70wt%、果胶4wt%-6wt%、异麦芽酮糖醇15wt%-40wt%、绿茶粉10wt%-30wt%。A dietary supplement capable of inhibiting postprandial blood sugar rise in diabetic patients, comprising the following components by weight percentage: polydextrose 50wt%-70wt%, pectin 4wt%-6wt%, isomalt 15wt%-40wt% , Green tea powder 10wt%-30wt%.
本发明所述的“包括”，意指其除所述组分外，还可以含有其他组分，这些其他组分赋予所述可抑制糖尿病患者餐后血糖升高的膳食补充剂以不同的特性。除此之外，本发明所述的“包括”，还可以替换为封闭式的“为”或“由……制成”。不管本发明所述可抑制糖尿病患者餐后血糖升高的膳食补充剂包括何种成分，所述膳食补充剂的重量百分比之和为100%。The "comprising" mentioned in the present invention means that in addition to the above-mentioned components, it may also contain other components, and these other components endow the dietary supplement capable of inhibiting postprandial blood sugar rise in diabetic patients with different characteristics . In addition, the "comprising" in the present invention can also be replaced with the closed "for" or "made of". No matter which ingredients are included in the dietary supplement capable of inhibiting postprandial blood sugar rise in diabetic patients according to the present invention, the sum of weight percentages of the dietary supplement is 100%.
本发明所述的可抑制糖尿病患者餐后血糖升高的膳食补充剂，将所用原料组分过筛或不过筛后混合均匀即可，之后可按照常规的制粒等方法制成固体饮料，也可不经制粒等直接服用。本发明所述的可抑制糖尿病患者餐后血糖升高的膳食补充剂日摄入量在10-50g即可。The dietary supplement that can inhibit postprandial blood sugar rise in diabetic patients according to the present invention can be obtained by sieving or not sieving the raw material components and mixing them evenly, and then making solid beverages according to conventional methods such as granulation. It can be taken as it is without granulation or the like. The daily intake of the dietary supplement capable of inhibiting postprandial blood sugar rise in diabetic patients according to the present invention is 10-50 g.
本发明所述的可抑制糖尿病患者餐后血糖升高的膳食补充剂以水溶性膳食纤维和低血糖生成指数的糖类为主要原料，安全无副作用，代谢不依赖胰岛素，且不过量增加饱腹感，因此不影响正常饮食，可在饭前服用，也可与正餐混合一起服用，使糖尿病患者能够告别少食多餐，在充分确保餐后血糖水平不升高的基础上，亦保证了可从食物中的获取做够的能量和微量元素，同时又可改善肠道菌群，防止便秘，预防癌症。The dietary supplement capable of inhibiting the postprandial blood sugar rise of diabetic patients according to the present invention uses water-soluble dietary fiber and carbohydrates with low glycemic index as main raw materials, is safe and has no side effects, does not rely on insulin for metabolism, and does not increase satiety excessively Therefore, it does not affect the normal diet. It can be taken before meals or mixed with main meals, so that diabetic patients can say goodbye to eating less and more meals. On the basis of fully ensuring that the blood sugar level does not rise after meals, it also ensures that it can be taken from Obtaining enough energy and trace elements from food can also improve intestinal flora, prevent constipation, and prevent cancer.
附图说明 Description of drawings
图1是试验例1中28名受试者的血糖平均值的变化图。FIG. 1 is a graph showing changes in the mean blood glucose values of 28 subjects in Test Example 1.
下面结合附图并通过具体实施方式来进一步说明本发明的技术方案，但下述的实例仅仅是本发明的简易例子，并不代表或限制本发明的权利保护范围，本发明的保护范围以权利要求书为准。The technical scheme of the present invention will be further described below in conjunction with the accompanying drawings and through specific implementation methods, but the following examples are only simple examples of the present invention, and do not represent or limit the scope of protection of the present invention. The scope of protection of the present invention is based on rights Requirements shall prevail.
具体实施方式 Detailed ways
为更好地说明本发明，便于理解本发明的技术方案，本发明的典型但非限制性的实施例如下：For better illustrating the present invention, facilitate understanding technical scheme of the present invention, typical but non-limiting embodiment of the present invention is as follows:
实施例1：Example 1:
一种可抑制糖尿病患者餐后血糖升高的膳食补充剂，包括如下重量百分比的组分：聚葡萄糖70wt%、果胶5wt%、异麦芽酮糖醇15wt%、绿茶粉10wt%。A dietary supplement capable of inhibiting postprandial blood sugar rise in diabetic patients, comprising the following components by weight percentage: 70wt% polydextrose, 5wt% pectin, 15wt% isomalt, and 10wt% green tea powder.
实施例2：Example 2:
一种可抑制糖尿病患者餐后血糖升高的膳食补充剂，包括如下重量百分比的组分：聚葡萄糖50wt%、黄蓍胶2wt%、魔芋胶2wt%、异麦芽酮糖醇40wt%、红枣粉6wt%。A dietary supplement capable of inhibiting postprandial blood sugar rise in diabetic patients, comprising the following components by weight percentage: polydextrose 50wt%, tragacanth gum 2wt%, konjac gum 2wt%, isomalt 40wt%, red date powder 6wt%.
实施例3：Example 3:
一种可抑制糖尿病患者餐后血糖升高的膳食补充剂，包括如下重量百分比的组分：聚葡萄糖20wt%、抗性淀粉20wt%、抗性糊精20wt%、菊粉20wt%、瓜尔豆胶5wt%、木糖醇10wt%、柠檬粉5wt%。A dietary supplement capable of inhibiting postprandial blood sugar rise in diabetic patients, comprising the following components by weight percentage: polydextrose 20wt%, resistant starch 20wt%, resistant dextrin 20wt%, inulin 20wt%, guar beans Glue 5wt%, xylitol 10wt%, lemon powder 5wt%.
实施例4：Example 4:
一种可抑制糖尿病患者餐后血糖升高的膳食补充剂，包括如下重量百分比的组分：聚葡萄糖30wt%、褐藻胶2wt%、葡萄糖10wt%、果糖10wt%、甘露糖醇10wt%、山梨糖醇8wt%、红枣粉20wt%、山药粉10wt%。A dietary supplement capable of inhibiting postprandial blood sugar rise in diabetic patients, comprising the following components by weight percentage: polydextrose 30wt%, alginate 2wt%, glucose 10wt%, fructose 10wt%, mannitol 10wt%, sorbose Alcohol 8wt%, red date powder 20wt%, yam powder 10wt%.
实施例5：Example 5:
一种可抑制糖尿病患者餐后血糖升高的膳食补充剂，包括如下重量百分比的组分：抗性淀粉8wt%、魔芋胶1wt%、半乳糖20wt%、核糖20wt%、赤藓糖醇20wt%、麦芽糖醇30wt%、柠檬酸1wt%。A dietary supplement capable of inhibiting postprandial blood sugar rise in diabetic patients, comprising the following components by weight percentage: resistant starch 8wt%, konjac gum 1wt%, galactose 20wt%, ribose 20wt%, erythritol 20wt% , maltitol 30wt%, citric acid 1wt%.
实施例6：Embodiment 6:
一种可抑制糖尿病患者餐后血糖升高的膳食补充剂，包括如下重量百分比的组分：聚葡萄糖97wt%、黄原胶1wt%、脱氧核糖1wt%、橘子粉1wt%。A dietary supplement capable of inhibiting postprandial blood sugar rise in diabetic patients, comprising the following components by weight percentage: polydextrose 97wt%, xanthan gum 1wt%, deoxyribose 1wt%, orange powder 1wt%.
实施例7：Embodiment 7:
一种可抑制糖尿病患者餐后血糖升高的膳食补充剂，包括如下重量百分比的组分：抗性糊精13wt%、黄蓍胶2wt%、阿拉伯树胶2wt%、葫芦巴胶2wt%、异麦芽酮糖醇1wt%、苹果粉80wt%。A dietary supplement capable of inhibiting postprandial blood sugar rise in diabetic patients, comprising the following components by weight percentage: resistant dextrin 13wt%, tragacanth gum 2wt%, acacia gum 2wt%, fenugreek gum 2wt%, isomalt Ketitol 1wt%, apple powder 80wt%.
实施例8：Embodiment 8:
一种可抑制糖尿病患者餐后血糖升高的膳食补充剂，包括如下重量百分比的组分：聚葡萄糖10wt%、菊粉5wt%、柚皮果胶5wt%、蓝莓果胶5wt%、异麦芽酮糖醇30wt%、半乳糖30wt%、碳酸氢钠15wt%。A dietary supplement capable of inhibiting postprandial blood sugar rise in diabetic patients, comprising the following components by weight percentage: polydextrose 10wt%, inulin 5wt%, pomelo peel pectin 5wt%, blueberry pectin 5wt%, isomaltone Sugar alcohol 30wt%, galactose 30wt%, sodium bicarbonate 15wt%.
实施例9：Embodiment 9:
一种可抑制糖尿病患者餐后血糖升高的膳食补充剂，包括如下重量百分比的组分：聚葡萄糖10wt%、抗性淀粉10wt%、抗性糊精10wt%、苹果果胶2wt%、柚皮果胶2wt%、蓝莓果胶2wt%、菠萝果胶2wt%、异麦芽酮糖醇20wt%、甘露糖醇20wt%、山梨糖醇20wt%、香蕉粉2wt%。A dietary supplement capable of inhibiting postprandial blood sugar rise in diabetic patients, comprising the following components by weight percentage: polydextrose 10wt%, resistant starch 10wt%, resistant dextrin 10wt%, apple pectin 2wt%, pomelo peel Pectin 2wt%, blueberry pectin 2wt%, pineapple pectin 2wt%, isomalt 20wt%, mannitol 20wt%, sorbitol 20wt%, banana powder 2wt%.
实施例10：Example 10:
一种可抑制糖尿病患者餐后血糖升高的膳食补充剂，包括如下重量百分比的组分：聚葡萄糖27wt%、苹果果胶8wt%、乳糖醇15wt%、绿茶粉50wt%。A dietary supplement capable of inhibiting postprandial blood sugar rise in diabetic patients, comprising the following components by weight percentage: polydextrose 27wt%, apple pectin 8wt%, lactitol 15wt%, green tea powder 50wt%.
试验例1：Test example 1:
试验人群：随机抽查28名糖尿病患者，年龄46-80岁，病程2-24年。Test population: 28 diabetic patients were randomly selected, aged 46-80 years, with a disease course of 2-24 years.
试验方法：试验第一天，测量受试者晚餐前血糖值和餐后2h血糖值。此后一星期，受试者进餐种类及食用量均与第一天相同并且保持运动量一致，均在晚餐前30min服用实施例10的膳食补充剂10g，测量受试者晚餐前血糖值和餐后2h血糖值。在试验过程中，受试者均未服用任何其他能降低血糖的药物，亦不存在其他导致血糖降低的因素。记录各血糖值并记载如表1所示：Test method: On the first day of the test, measure the subjects' blood glucose levels before dinner and 2 hours after meals. One week thereafter, the subjects ate the same type and amount of food as the first day and kept the same amount of exercise. They all took 10 g of the dietary supplement of Example 10 30 minutes before dinner, and measured the blood sugar level of the subjects before dinner and 2 hours after meal. Blood sugar level. During the test, none of the subjects took any other drugs that can lower blood sugar, and there were no other factors that caused blood sugar to drop. Record each blood glucose level and record it as shown in Table 1:
表1Table 1
试验结果：如图1所示，在服用本发明的可抑制糖尿病患者餐后血糖升高的膳食补充剂一星期后，28名受试者的餐前血糖值基本无变化，而平均餐后血糖值从开始的12.3±2.6mmol/L降低到了11.0±3.3mmol/L，呈现出明显的下降趋势。Test results: as shown in Figure 1, after taking the dietary supplement of the present invention that can inhibit postprandial blood sugar rise in diabetic patients for one week, the pre-prandial blood glucose values of 28 subjects did not change substantially, while the average postprandial blood glucose The value decreased from the initial 12.3±2.6mmol/L to 11.0±3.3mmol/L, showing an obvious downward trend.
根据本试验，糖尿病患者仅在每日晚餐前服用少剂量（10g）本发明的可抑制糖尿病患者餐后血糖升高的膳食补充剂一星期，餐后血糖值即出现了明显的下降，而正常饮食不受影响，做够获取足够的能量和微量元素，安全无副作用。According to this test, diabetic patients only take a small dose (10g) of the dietary supplement of the present invention that can inhibit the rise of postprandial blood sugar in diabetic patients for a week before dinner every day, and the postprandial blood glucose level has significantly decreased, while normal The diet is not affected, enough energy and trace elements can be obtained by doing enough, it is safe and has no side effects.
应该注意到并理解，在不脱离后附的权利要求所要求的本发明的精神和范围的情况下，能够对上述详细描述的本发明做出各种修改和改进。因此，要求保护的技术方案的范围不受所给出的任何特定示范教导的限制。It should be noted and understood that various modifications and improvements can be made to the invention described in detail above without departing from the spirit and scope of the invention as claimed in the appended claims. Accordingly, the scope of the claimed technical solution is not limited by any particular exemplary teaching given.
申请人声明，本发明通过上述实施例来说明本发明的原料配比及制备步骤，但本发明并不局限于上述配比及制备步骤，即不意味着本发明必须依赖上述制备步骤才能实施。所属技术领域的技术人员应该明了，对本发明的任何改进，对本发明所选用原料的等效替换及辅助成分的添加、具体方式的选择等，均落在本发明的保护范围和公开范围之内。The applicant declares that the present invention illustrates the ratio of raw materials and preparation steps of the present invention through the above-mentioned examples, but the present invention is not limited to the above-mentioned ratio and preparation steps, that is, it does not mean that the present invention must rely on the above-mentioned preparation steps to be implemented. Those skilled in the art should understand that any improvement of the present invention, the equivalent replacement of the selected raw materials in the present invention, the addition of auxiliary components, the selection of specific methods, etc., all fall within the scope of protection and disclosure of the present invention.
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| CN105266005A (en) * | 2015-10-23 | 2016-01-27 | 同福碗粥股份有限公司 | A kind of multigrain porridge with low glycemic index and preparation method thereof |
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| CN107080265A (en) * | 2017-06-20 | 2017-08-22 | 慧谷生命科技湖北有限公司 | Suitable for the strange sub- seed dietary fiber meal replacement powder of diabetes |
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