CN102988444B - Preparation method of blood circulation promoting and meridian obstruction removing pill for preventing and treating osteoporosis - Google Patents
Preparation method of blood circulation promoting and meridian obstruction removing pill for preventing and treating osteoporosis Download PDFInfo
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- 239000006187 pill Substances 0.000 title abstract description 8
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Abstract
The invention provides a preparation method of a blood circulation promoting and meridian obstruction removing pill for preventing and treating osteoporosis. The pill is prepared by uniformly mixing, crushing and pelleting the following components in parts by weight: 4 to 6 parts of hemlock parsley, 8 to 12 parts of safflower, 2 to 4 parts of notopterygium root, 8 to 12 parts of Chinese angelica, and 10 to 30 parts of chondroitin sulfate. The product has good effect of preventing and treating osteoporosis.
Description
Technical field
The invention belongs to field of medicaments, be specifically related to a kind of preparation method of preventing and treating osteoporotic promoting blood circulation to remove obstruction in the collateral ball.
Background technology
Osteoporosis (osteoporosis) is a kind of systemic osteopathia, it is characterized in that bone amount declines and the fine structure of bone destroys, the fragility showing as bone increases, and the danger of thus fracturing greatly increases, even also easily fracture in slight wound or atraumatic situation.Osteoporosis is a kind of multifactor caused chronic disease.Before fracture occurs, usually without Special Clinical Manifestation.This sick women, more than male, is common in postmenopausal women and old people.Along with the increase of China's aging population, developing osteoporosis rate is in ascendant trend, is all a health problem merited attention in China and even the whole world.
Motherland's medical science think primary disease generation, development and " kidney qi " closely related, " Plain Questions is inverse adjusts opinion " is said: " kidney not life; then marrow can not be expired ", " Plain Questions six saves Tibetan and resembles opinion " is said: " kidney person, main stings, the dominator of storing essence; smart part is also; its Hua Fa, and it fills at bone " ", therefore good effect is all obtained to its employing invigorating the kidney and strengthening the bones, invigorating the spleen and benefiting QI, promoting blood circulation to remove obstruction in the collateral.
The traditional Chinese medical science adopts differentiation of symptoms and signs for classification of syndrome, for different types, adopts the prescription of suiting the medicine to the illness.As adopted the prescription of nourishing the liver and kidney, bone and muscle strengthening for deficiency of the liver and kidney, as square medicine: chien pu hu chien wan: Colla Plastri Testudinis 2 parts, Colla cornus cervi 2 parts, Tigris shin (now using Os Canitis generation) 2 parts, Radix Polygoni Multiflori 2 parts, Radix Cyathulae 2 parts, the Cortex Eucommiae 2 parts, Herba Cynomorii 2 parts, Radix Angelicae Sinensis 2 parts, Radix Rehmanniae Preparata 2 parts, Radix Clematidis 2 parts, Cortex Phellodendri 1 part, Radix Ginseng 1 part, Rhizoma Et Radix Notopterygii 1 part, the Radix Paeoniae Alba 1 part, the Rhizoma Atractylodis Macrocephalae 1 part, great river Radix Aconiti Lateralis Preparata 1.5 parts, Mel is appropriate.Grind as smalls, refined honey ball is as large in Semen phaseoli radiati).Often take 10 grams, light salt brine send down on an empty stomach, every day 2 ~ 3 times.
The prescription of Yishen Jianpi is adopted, as square medicine: SHENLING BAISHU SAN closes Yougui Yin, the kidney-Yang-Reinkforcing Decotion: Semen Nelumbinis (peeling) 500 grams, Semen Coicis 50 grams for yang deficiency of spleen and stomache, contracting Fructus Amomi 50 grams, Radix Platycodonis (stir-fry makes buff) 50 grams, (Sucus Zingberis soaks Semen Lablab Album, peeling, micro-stir-fry) 75 grams, Poria 100 grams, Radix Ginseng 100 grams, 100 grams, Radix Glycyrrhizae (stir-fry), the Rhizoma Atractylodis Macrocephalae 100 grams, Rhizoma Dioscoreae 100 grams.Grind as smalls, each serving 6 grams, Fructus Jujubae is decocted soup and is taken.
The prescription of blood-activating and qi-promoting, removing obstruction in the collateral to relieve pain is adopted for qi stagnation and blood stasis type, as square medicine: Traditional Chinese medicine decoction for treating-ache and expelling atagnate: Radix Gentianae Macrophyllae 3 grams, Rhizoma Chuanxiong 6 grams, 9 grams, Semen Persicae, 9 grams, Flos Carthami, 6 grams, Radix Glycyrrhizae, Rhizoma Et Radix Notopterygii 3 grams, Myrrha 6 grams, Radix Angelicae Sinensis 9 grams, Oletum Trogopterori (stir-fry) 6 grams, Rhizoma Cyperi 3 grams, Radix Achyranthis Bidentatae 9 grams, Pheretima 6 grams.Be decocted in water for oral dose, avoid cold and uncooked food greasy, be not taken by pregnant women.
Chondroitin sulfate (Chondroitin sulfate) is present in animal cartilage in a large number, is the acid mucopolysaccharide extracting preparation from animal tissue.Chondroitin sulfate is the one of glycosaminoglycans, by D-glucuronic acid and N-acetylamino galactosamine with β-1, the polysaccharide of the repetition disaccharide unit composition that 4-glycosidic bond is formed by connecting, and Sulfation is there is on the C-4 position of N-acetylamino galactosamine or C-6 position hydroxyl, be mainly used in arthritis, eye drop etc., research shows, chondroitin sulfate can promote osteoblast proliferation and new bone formation." sulfated compound chrondroitin is to the therapeutical effect of rats with osteoporosis for scientific and technical literature
" (Liu Xiuju, Zhang Jixian, Mu Zhongxiang etc., " food and pharmaceutical " 05 phase in 2008) study the effect that sulfated compound chrondroitin treats the rats with osteoporosis of Induced by Retinoic Acid, result shows, compare with model group, high, the middle dosage group of sulfated compound chrondroitin significantly can increase rat body weight, improves bone mineral content and bone density, reduces serum alkaline phosphatase (ALP) level, and significantly can improve the biomechanical parameter of femur, there is therapeutical effect to rats with osteoporosis.
There is no at present and the drug regimen of Chinese medicine and chondroitin sulfate is studied.
Summary of the invention
The invention provides a kind of preparation method of preventing and treating osteoporotic promoting blood circulation to remove obstruction in the collateral ball, adopt Chinese medicine and the chondroitin sulfate combined treatment osteoporosis of blood-activating and qi-promoting, removing obstruction in the collateral to relieve pain for qi stagnation and blood stasis type.
The concrete technical scheme of the present invention is as follows:
Prevent and treat a preparation method for osteoporotic promoting blood circulation to remove obstruction in the collateral ball, comprise the steps:
1) Rhizoma Chuanxiong 6 parts of weight portion is got, 12 parts, Flos Carthami, Rhizoma Et Radix Notopterygii 4 parts, Radix Angelicae Sinensis 12 parts of dryings;
2) mix homogeneously with chondroitin sulfate 10-30 part, pulverized 80-100 mesh sieve, mix homogeneously;
3) in right amount, general ball, converts by medicated powder total amount for molding, tune mulse, the heavy 0.1g/ grain of grain, and the total grain number of total amount ÷ 0.1g/ grain=finished product, with the mothers and sons of total quantity, by complete for general for medicated powder system;
4) dry: electrical heating or steam drying;
5) granulate subpackage, pack by every pouch 50 about 6g, every 10 bags is 1 box, seals and get final product.
The preparation method of above-mentioned Bushen Zhuanggu pills, preferably getting weight portion is Rhizoma Chuanxiong 4-6 part, Flos Carthami 8-12 part, Rhizoma Et Radix Notopterygii 2-4 part, and Radix Angelicae Sinensis 8-12 part mixs homogeneously with chondroitin sulfate 10-30 part, through pulverizing, pill and get final product.
Detailed description of the invention
Below in conjunction with instantiation, technical scheme of the present invention is described further, contributes to understanding the present invention, but do not limit content of the present invention.
Embodiment 1
Take Rhizoma Chuanxiong 4g, Flos Carthami 8g, Rhizoma Et Radix Notopterygii 2g, Radix Angelicae Sinensis 8g is dry, adds chondroitin sulfate 10g, pulverizes 80-100 mesh sieve, mix homogeneously.In right amount, general ball, by the conversion of medicated powder total amount, the heavy 0.1g/ grain of grain, the total grain number of total amount ÷ 0.1g/ grain=finished product, with the mothers and sons of total quantity, by complete for general for medicated powder system for molding, tune mulse.By obtained pill through steam drying, granulate subpackage, pack by every pouch 50 about 6g, every 10 bags is 1 box, seals and get final product.
Embodiment 2
Take Rhizoma Chuanxiong 5g, Flos Carthami 10g, Rhizoma Et Radix Notopterygii 3g, Radix Angelicae Sinensis 10g, add chondroitin sulfate 20g, pulverize 80-100 mesh sieve, mix homogeneously.In right amount, general ball, by the conversion of medicated powder total amount, the heavy 0.1g/ grain of grain, the total grain number of total amount ÷ 0.1g/ grain=finished product, with the mothers and sons of total quantity, by complete for general for medicated powder system for molding, tune mulse.By obtained pill through steam drying, granulate subpackage, pack by every pouch 50 about 6g, every 10 bags is 1 box, seals and get final product.
Embodiment 3
Take Rhizoma Chuanxiong 6g, Flos Carthami 12g, Rhizoma Et Radix Notopterygii 4g, Radix Angelicae Sinensis 12g, add chondroitin sulfate 30g, pulverize 80-100 mesh sieve, mix homogeneously.In right amount, general ball, by the conversion of medicated powder total amount, the heavy 0.1g/ grain of grain, the total grain number of total amount ÷ 0.1g/ grain=finished product, with the mothers and sons of total quantity, by complete for general for medicated powder system for molding, tune mulse.By obtained pill through steam drying, granulate subpackage, pack by every pouch 50 about 6g, every 10 bags is 1 box, seals and get final product.
Claims (2)
1. prevent and treat a preparation method for osteoporotic promoting blood circulation to remove obstruction in the collateral ball, it is characterized in that comprising the steps:
1) Rhizoma Chuanxiong 6 parts of weight portion is got, 12 parts, Flos Carthami, Rhizoma Et Radix Notopterygii 4 parts, Radix Angelicae Sinensis 12 parts of dryings;
2) mix homogeneously with chondroitin sulfate 10-30 part, pulverized 80-100 mesh sieve, mix homogeneously;
3) in right amount, general ball, converts by medicated powder total amount for molding, tune mulse, the heavy 0.1g/ grain of grain, and the total grain number of total amount ÷ 0.1g/ grain=finished product, with the mothers and sons of total quantity, by complete for general for medicated powder system;
4) dry: electrical heating or steam drying;
5) granulate subpackage, by every pouch 50 particle packing, every 10 bags is 1 box, seals and get final product.
2. prevent and treat a preparation method for osteoporotic promoting blood circulation to remove obstruction in the collateral ball, it is characterized in that comprising the steps:
1) getting weight portion is Rhizoma Chuanxiong 4-6 part, Flos Carthami 8-12 part, Rhizoma Et Radix Notopterygii 2-4 part, and Radix Angelicae Sinensis 8-12 part is dry;
2) mix homogeneously with chondroitin sulfate 10-30 part, pulverized 80-100 mesh sieve, mix homogeneously;
3) in right amount, general ball, converts by medicated powder total amount for molding, tune mulse, the heavy 0.1g/ grain of grain, and the total grain number of total amount ÷ 0.1g/ grain=finished product, with the mothers and sons of total quantity, by complete for general for medicated powder system;
4) dry: electrical heating or steam drying;
5) granulate subpackage, by every pouch 50 particle packing, every 10 bags is 1 box, seals and get final product.
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| CN201210391164.2A CN102988444B (en) | 2012-10-16 | 2012-10-16 | Preparation method of blood circulation promoting and meridian obstruction removing pill for preventing and treating osteoporosis |
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| CN201210391164.2A CN102988444B (en) | 2012-10-16 | 2012-10-16 | Preparation method of blood circulation promoting and meridian obstruction removing pill for preventing and treating osteoporosis |
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| CN102988444A CN102988444A (en) | 2013-03-27 |
| CN102988444B true CN102988444B (en) | 2015-02-25 |
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Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104383524B (en) * | 2014-11-27 | 2016-09-21 | 桂林瑞丰环保微生物应用研究所 | A kind of health product strengthening sclerotin |
| CN104840597A (en) * | 2015-05-27 | 2015-08-19 | 蔡永柱 | Chondroitin sulfate pills and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1355036A (en) * | 2000-11-29 | 2002-06-26 | 卿多舜 | Ointment for treating ostalgia and its preparing process |
| CN1742876A (en) * | 2005-09-29 | 2006-03-08 | 沈阳中药制药有限公司 | Chinese medicine for treating tractures and preparation for making plaster thereof |
| CN102258750A (en) * | 2011-07-14 | 2011-11-30 | 张峻玮 | Preparation method of volcanic mud black ointment |
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2012
- 2012-10-16 CN CN201210391164.2A patent/CN102988444B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1355036A (en) * | 2000-11-29 | 2002-06-26 | 卿多舜 | Ointment for treating ostalgia and its preparing process |
| CN1742876A (en) * | 2005-09-29 | 2006-03-08 | 沈阳中药制药有限公司 | Chinese medicine for treating tractures and preparation for making plaster thereof |
| CN102258750A (en) * | 2011-07-14 | 2011-11-30 | 张峻玮 | Preparation method of volcanic mud black ointment |
Non-Patent Citations (2)
| Title |
|---|
| 膝关节骨性关节炎治疗进展;杜杰等;《临床军医杂志》;20080430;第36卷(第2期);301-304页 * |
| 膝骨性关节炎的中西医治疗方法概述;欧阳建江等;《现代中西医结合杂志》;20030630;第12卷(第12期);1324-1326页 * |
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