CN102908174B - Medical instrument for interventional therapy - Google Patents
Medical instrument for interventional therapy Download PDFInfo
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- CN102908174B CN102908174B CN201210389823.9A CN201210389823A CN102908174B CN 102908174 B CN102908174 B CN 102908174B CN 201210389823 A CN201210389823 A CN 201210389823A CN 102908174 B CN102908174 B CN 102908174B
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- Surgical Instruments (AREA)
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Abstract
The invention relates to a medical instrument for interventional therapy. The medical instrument comprises at least one fabric body and a fixing and connecting device, wherein each fabric body is composed of a plurality of knitting yarns, and a part of the knitting yarns is provided with knitting yarn fixing ends; and the fixing and connecting device comprises an inner sleeve and an outer sleeve, the inner sleeve is fixed in the outer sleeve, the knitting yarn fixing ends are fixed between the inner sleeve and the outer sleeve, the inner sleeve is completely hollow and two ends of the inner sleeve are open. The medical instrument solves the problems that an existing fixing and connecting device for the fabric body planted into the medical instrument protrudes outwards or protrudes much and the like, so that the outer surface near the fixing and connecting device is flatter, and safe, convenient and controllable threaded connection manner is reserved.
Description
Technical field
The present invention relates to a kind of medical apparatus and instruments, particularly relate to a kind of method got involved by microcatheter technology utilization and be sent to the medical apparatus and instruments that human body selectes position.
Background technology
Utilizing the method got involved to carry out disease treatment by microcatheter technology is utilize increasing Therapeutic Method at present, and Catheter Interventional Therapy method places various material, apparatus and medicine heart, artery and vein vascular to human body.
The defect of stopper (as atrial septal defect (ASD) stopper, ventricular septal defect (VSD) stopper, patent ductus arteriosus (PDA) stopper, patent foramen ovale (PFO) stopper etc.) to heart is placed as by intubation intervention method, shutoff defect, to treat congenital heart disease.This is the insertion type medical apparatus and instruments that a kind of Application comparison is many, is generally by being threaded between apparatus and pusher, is transported to the position in predetermined human body by pusher, then separates Leave out thread to disconnect the connection of apparatus and pusher.For this apparatus, it is threaded and can realizes the reliable and secure connection of apparatus and pusher, controllable release can be realized simultaneously, if namely the size Selection of apparatus is improper, or apparatus launch bad time, can again apparatus income delivery conduit in, the suitable apparatus renewed, reappose, last reliable release.
For another example, place stopper in left auricle by intubation intervention method, prevent to cause left auricle due to atrial fibrillation and form thrombosis, this thrombosis goes upward to the apoplexy that brain causes; Or prevent this XUESHUANTONG to cross human body blood circulation arrival other positions of health, the systemic thromboembolism caused.Put stopper in left auricle, shutoff left auricle, block the blood flow entering left auricle, can eliminate and cause the thrombosed risk of left auricle due to atrial fibrillation, prevention of stroke.Such apparatus is all be connected with pusher by screw thread usually at present.
When being placed by intubation intervention method in the heart of these apparatuses to human body, artery and vein vascular, left auricle, due to heart, the artery and vein vascular of human body, especially the anatomical structure of left auricle is complicated, require that apparatus accurately arrives predetermined position, well to adapt to the anatomical structure of predetermined position, mechanical requirements and hemodynamics requirement simultaneously, a well design must be had to the structure of apparatus.Under the prerequisite only human body being produced to Micro trauma, first puncturing near the skin place of blood vessel, seal wire is from puncture orifice intravasation, conduit is under the guiding of seal wire, its one end arrives predetermined position, and the other end is stayed external, then utilizes conduit and pusher that apparatus is sent to predetermined position.When carrying out this type of operation, require the conduit of very little flexibility, conduit and seal wire will be designed to there is good development under X-ray simultaneously.Once conduit reaches predetermined position, remove seal wire, utilize passage that pusher is set up by conduit the end of apparatus guiding catheter, when apparatus all exposes from the end of conduit, apparatus will disconnect with pusher, to realize the release of apparatus.
At present, no matter be the stopper be placed on heart defect, still the stopper in left auricle is placed on, it is connected major part employing and is threaded with pusher, this is threaded is will install a threaded primary nut in the one or both ends of stopper, and this primary nut is normally given prominence to outside stopper net dish (or body).And, because existing stopper is all woven by a lot of root fine wire to form usually, knitted body needs the parts concentrating fixing many one metal wires, therefore must first the end-contraction of these one metal wires be fixed in a small sleeve, then screwed primary nut is fixed on outside small sleeve again, as depicted in figs. 1 and 2, knitted body comprises at least one and fixes and connecting device.
Similarly, vascular plug, intravascular stent and thrombus filter also can be woven by many one metal wires and form, and also may need to concentrate and fix these braided wires, and its knitted body also comprises so fixing and connecting device.Now, these medical apparatus and instruments run into same problem, its fix and connecting device oversize, easily protrude from cardiovascular organization surface and be unfavorable for that endothelium is climbed and cover and produce higher thrombus source, or rub comparatively greatly with cardiovascular organization and cause inflammation and damage.
The limitation that screw connection on implantation instrument of the prior art exists:
The structure of the screw connection of the implant (as stopper) of 1, conventional in prior art insertion type medical apparatus and instruments, as shown in Figure 1.First the end of a lot of one metal wires of knitting disc 5 is drawn in the inside being fixed on sleeve 3 again, and then the extension 6 of nut 1 is enclosed within the outer wall of sleeve 3, then the extension 6 of nut 1 is welded with sleeve 3.As shown in Figure 2, the end of pusher 31 must have the external screw thread 32 of sufficient length to be engaged with nut 1, and it is safe and reliable that guarantee is threaded.But, as shown in Figure 3, according to theory of mechanics and existing process technology, the end of the external screw thread 32 of pusher 31 has one section of incomplete afterbody 33 of (generally needing 0.5 ~ 1mm) thread at least, the incomplete afterbody 33 of thread can not fully and nut 1 be engaged, weaken due bonding strength.End due to pusher 31 is subject to the stop of the boundling weld part 2 of knitting disc 5, afterbody 33 can not reach the outside of nut 1, but afterbody 33 occupies a segment length of nut 1 and reduces the fastness be threaded, therefore require that nut 1 suitably increases length, such nut 1 has larger part and gives prominence to outside stopper knitting disc 5, and general nut 1 needs outstanding 2 ~ 5 millimeters.After being implanted to the predetermined position in heart, this giving prominence to can not change, and there is larger thrombosis rate at the position outstanding at this.Especially for use in the stopper on left auricle, because in the left auricle of atrial fibrillation patient that is placed to of occluder for left auricle, according to dissection and the physiological structure of human body, the blood flow near patient's left auricle of atrial fibrillation is comparatively slow, very easily forms thrombosis.Climb at the endothelium at this outstanding position covers comparatively slowly simultaneously, because metal parts is chronically exposed in tissue or blood, can cause the increased risk of the harmful metal ion be discharged in blood.Another unfavorable factor affecting the safety of apparatus is, this outstanding position larger degree can affect the type of flow of the original blood of human body, can touch the tissue having influence on surrounding simultaneously and cause damage.
2, after implanting such medical apparatus and instruments, patient may need the intervene operation implementing other again, now, the apparatus (as seal wire etc.) used can through implantation instrument side, outstanding owing to having, meeting hook or yoke are arrived, normally carrying out of impact operation.
3, when making such medical apparatus and instruments, need through twice fixing operation, first the tinsel of sleeve 3 and knitting disc 5 is fixed, then sleeve 4 and nut 1 are fixed, Making programme is more, and parts are also more, the time of making can be increased like this, making cumulative errors can be increased simultaneously, be unfavorable for ensuring the quality of products, improve and realize difficulty.
4, fixing for sleeve 3 and braided wires stiff end, usually use argon arc welding, but the energy size that argon arc welding is applied on parts is uncontrollable; braided wires stiff end often can be caused to be blown; processing quality is unstable, and the radiation of argon arc welding is simultaneously comparatively large, larger to the harm of the personnel of operation.
5, the structure of the nut 1 of prior art employing is more complicated, and difficulty of processing is larger.
Summary of the invention
The technical problem to be solved in the present invention be to provide a kind of for interventional therapy with medical apparatus and instruments that is fixing and connecting device, to solve the fixing of the knitted body of implanted medical device of the prior art and connecting device outwardly or the problem such as its outstanding degree is larger, thus it is fixed and outer surface near connecting device more smooth, retain the safe and simple controlled of thread connecting mode simultaneously.
Solving the technical scheme that technical problem of the present invention adopts is: provide a kind of medical apparatus and instruments for interventional therapy, comprise at least one knitted body, at least one knitted body described is made up of many braided wires, at least one braided wires among described many braided wires has braided wires stiff end, also comprise a fixing and connecting device, described fixing and connecting device comprises an inner sleeve and a trocar sheath, described inner sleeve is fixed on the inside of described trocar sheath, described braided wires stiff end is fixed between the outer circumference surface of described inner sleeve and the inner peripheral surface of described trocar sheath, described inner sleeve is complete hollow, the two ends of described inner sleeve are all open, the material at least partially of described braided wires stiff end melts and is filled in the gap between inner sleeve and trocar sheath, at least one circle of laser beam continuous welding, at described braided wires stiff end and overallly between described inner sleeve and trocar sheath forms annular weld part.
As the further improvement of medical apparatus and instruments of the present invention, the length of described inner sleeve substantially equal with the length of trocar sheath (both differences only 10%).
As the further improvement of medical apparatus and instruments of the present invention, the difference of the internal diameter of described trocar sheath and the external diameter of described inner sleeve, equals the twice (both differences only 10%) of the cross section maximum gauge of described braided wires substantially.
As the further improvement of medical apparatus and instruments of the present invention, described inner sleeve has female thread.
As the further improvement of medical apparatus and instruments of the present invention, the length of described inner sleeve is 1 ~ 2 millimeter, and described female thread runs through whole inner sleeve.
As the further improvement of medical apparatus and instruments of the present invention, described braided wires stiff end is evenly distributed on the outer circumference surface of described inner sleeve.
As the further improvement of medical apparatus and instruments of the present invention, in the outer face of described inner sleeve and described trocar sheath, described braided wires stiff end and overallly between described inner sleeve and trocar sheath forms annular weld part.
As the further improvement of medical apparatus and instruments of the present invention, the step that between described trocar sheath and described inner sleeve one of described weld part is annular is formed, and the height of described step is 0.2 ~ 0.8 millimeter, and described weld part is formed by laser weld.
As the further improvement of medical apparatus and instruments of the present invention, described fixing and connecting device is positioned at the inside of at least one knitted body described.
As the further improvement of medical apparatus and instruments of the present invention, described fixing and connecting device is connected with an outer face of one of them knitted body, and described outer face is smooth.
Compared with prior art, the present invention possesses following advantage: 1, knitted body remains outer surface and is similar to burnishing surface or little outstanding after implant into body, the climbing of endothelium of accelerating equipment surfaces is covered, at utmost reduce thrombosis rate, reduce harmful metal ion to the release in blood, farthest reduce the impact that medical apparatus and instruments flows on blood of human body, avoid the medical apparatus and instruments implanted to hinder the operation of subsequent instrument simultaneously.2, product structure and Making programme simplify, and reduce fabrication error, are conducive to improving conforming product rate.
Accompanying drawing explanation
Below in conjunction with drawings and Examples, the invention will be further described, in accompanying drawing:
Fig. 1 is the schematic diagram of interatrial septum of the prior art stopper.
Fig. 2 is the schematic diagram that the interatrial septum stopper in Fig. 1 is connected with pusher.
Fig. 3 is the enlarged diagram of the end of pusher.
Fig. 4 is the side partial schematic diagram of the first embodiment of medical apparatus and instruments of the present invention, and it comprises at least one knitted body and at least one is fixed and connecting device.
Fig. 5 is the schematic diagram that fixing and connecting device in Fig. 4 and pusher are connected.
Fig. 6 is the side schematic view of the second embodiment of medical apparatus and instruments of the present invention, and this medical apparatus and instruments is the interatrial septum stopper with an introversive fixing and connecting device.
Fig. 7 is the enlarged drawing of the fixing and connecting device in Fig. 6.
Fig. 8 is the side schematic view of the 3rd embodiment of medical apparatus and instruments of the present invention, and this medical apparatus and instruments is the occluder for left auricle with an introversive fixing and connecting device.
Fig. 9 is the enlarged drawing of the fixing and connecting device in Fig. 8.
Figure 10 is the axonometric chart of the occluder for left auricle in Fig. 8.
Figure 11 is the another embodiment of the fixing of medical apparatus and instruments of the present invention and connecting device.
Detailed description of the invention
In order to make object of the present invention, technical scheme and advantage clearly understand, below in conjunction with drawings and Examples, the present invention is further elaborated.Should be appreciated that specific embodiment described herein only in order to explain the present invention, be not intended to limit the present invention.
The invention provides a kind of medical apparatus and instruments for interventional therapy, it comprises at least one knitted body, at least one knitted body described is made up of many braided wires, braided wires at least partially among described many braided wires has braided wires stiff end, this medical apparatus and instruments also comprises a fixing and connecting device, described fixing and connecting device comprises an inner sleeve and a trocar sheath, described inner sleeve is fixed on the inside of described trocar sheath, described braided wires stiff end is fixed between the outer circumference surface of described inner sleeve and the inner peripheral surface of described trocar sheath, described inner sleeve is complete hollow, the two ends of described inner sleeve are all open.
The aspects such as medical apparatus and instruments concrete structure of the present invention and making are illustrated below by way of multiple embodiment.
Embodiment 1:
As shown in Figure 4, the medical apparatus and instruments of the present embodiment comprise at least one knitted body 5 and be connected with knitted body 5 at least one fix and connecting device, knitted body 5 is made up of many braided wires, usually weaves with tinsel, such as nitinol alloy wire, has excellent elasticity to make knitted body 5.The end of many braided wires, the braided wires stiff end 7 namely in Fig. 4, can collect and be fixed on this and to fix and on connecting device.In the prior art, the medical apparatus and instruments with this type of architectural feature comprises vascular plug, patent ductus arteriosus (PDA) stopper, atrial septal defect (ASD) stopper, patent foramen ovale (PFO) stopper, left auricle (LAA) stopper, thrombus filter and intravascular stent etc.The remainder of this medical apparatus and instruments is only connected with knitted body 5 and does not fix with this and connecting device is connected, and Gu Tuzhong does not show the remainder of medical apparatus and instruments.Such as, the general near cylindrical of knitted body 5 of vascular plug, the knitted body 5 of PDA stopper can be bell, and the knitted body 5 of ASD stopper is dual disc, PFO stopper can be made up of a knitting disc and some spoke support bars, and LAA stopper can be made up of a knitting disc and an anchor portion.This class medical apparatus and instruments all sets up connection status as shown in Figure 5 by the fixing and connecting device on knitted body 5 and pusher 31, is separated after being positioned tissue with pusher 31 again.
This is fixed and connecting device comprises short nut 11 (also can be described as: inner sleeve) and short sleeve 12 (also can be described as: trocar sheath), the internal diameter of short sleeve 12 is slightly larger than the external diameter of short nut 11, both differences also should slightly larger than the twice of the maximum gauge of braided wires (braided wires generally has same diameter), short nut 11 is nested in the inside of short sleeve 12, and this braided wires stiff end 7 is fixed in the gap between short nut 11 and short sleeve 12.This short nut 11 has female thread, and its two ends open completely and do not stopped, the pusher 31 being provided with external screw thread 32 at end can pass whole short nut 11, and the afterbody 32 of pusher reaches the outside of short nut 11, as shown in Figure 5.
In the prior art, as shown in Figure 2, the screw thread of nut 1 does not run through whole length (existence due to nut extension 6), and the inner of its screw thread by sleeve 3 and boundling weld part 2 clogging, the outer end of nut 1 is only had to be open, pusher 31 cannot pass whole nut 1, and the thread line of the afterbody 33 of pusher 31 is imperfect, as shown in Figure 3, therefore afterbody 33 closely can not be engaged with the female thread of nut 1, therefore, the interlude (thread at this place has complete profile) of the external screw thread 32 of main dependence pusher 31 is engaged nut 1, the threaded inner end of nut 1 has one section " dead length " can not be used for firmly connecting this pusher 31, this just requires that the effective length increasing nut 1 is to compensate " the dead length " of its screw thread, and nut extension 6 also can increase the total length of nut 1 further, nut 1 and the total length of nut extension 6 are less than 2 millimeters just cannot ensure firm connection, the total length of its reality is about 3 ~ 5 millimeters.
In the present embodiment, as shown in Figure 5, female thread due to short nut 11 can run through its whole length (not having nut extension 6), and pusher can pass whole short nut 11, the screw initial thread end of pusher can be exposed at outside short nut 11, only be engaged short nut 11 by the interlude of the screw thread of pusher, avoid above-mentioned " dead length ", make the length of whole short nut 11 effectively can fix pusher.Therefore, the length of the short nut 11 of the present embodiment may be as little to 1 ~ 2 millimeter, and the length of short sleeve 12 is preferably substantially equal with the length of short nut 11, and the length of short sleeve 12 also can be as short as 1 ~ 2 millimeter.
After the knitted body 5 precasting this medical apparatus and instruments, the fixing of the present embodiment and connecting device can be made by the following method.
The first step is assembling, overlays on the lateral wall of short nut 11, then penetrate among short sleeve 12 by these braided wires stiff ends 7 together with short nut 11 by dispersed for the many braided wires stiff ends 7 needing to be fixed together; Or, first many braided wires stiff ends 7 are passed short sleeve 12, shorter nut 11 are embedded in the centre of short sleeve 12 and these braided wires stiff ends 7, and allow braided wires stiff end 7 be dispersed in the periphery of short nut 11.Further, make the outer face of short nut 11 substantially parallel with the outer face of short sleeve 12, braided wires stiff end 7 slightly protrudes from the outer face of short nut 11 and short sleeve 12.
Next step is welding, with laser beam the material at least partially of braided wires stiff end 7 melted and be filled in the gap between short nut 11 and short sleeve 12, at least one circle of laser beam continuous welding, near the outer face of short nut 11 and short sleeve 12, form an annular more smooth integral solder portion 13, braided wires stiff end 7, short nut 11 and short sleeve 12 are welded together by the integral solder portion 13 between them.
Finally utilize known technology, knitted body 5 is put into corresponding mould, formed the shape of needs by heat treated mode.In the prior art, be generally a lot of root braided wires stiff end 7 is gathered penetrate among sleeve 3, with argon arc welding, then sleeve 3 inserted among nut 1, weld again.By improvement of the present invention, save once assembling and once weld, not only simplifying production procedure and raise the efficiency, also helping and reduce fabrication error raising conforming product rate.And prior art nut 1 used is longer, processing all more complicated of its screw thread and nut extension 6, comparatively speaking, the structure of the short nut 11 that medical apparatus and instruments of the present invention adopts is comparatively simple.
Fixing and the connecting device of the medical apparatus and instruments (stopper) that the present embodiment is produced, length outstanding outside stopper knitting disc will significantly reduce, its total length only has 1/3rd of the screw connection length of prior art usually, and amount of metal used also reduces to less than 1/3rd.After such stopper is implanted to human vas or heart, endotheliocyte is also easily climbed and is layed onto on described fixing and connecting device, the incidence rate of thrombosis can be reduced significantly, effectively reduce the impact of this connecting device on human bloodstream simultaneously, effectively reduce harmful metal ion to the release in blood.
Embodiment 2:
As shown in Figure 6 and Figure 7, the fixing and connecting device of dual disc stopper is also fixed together by short nut 11, short sleeve 12 and integral solder portion 13 between the two and forms.The main distinction of itself and embodiment 1 is: fixing and connecting device is in the inside of knitted body 5, and integral solder portion 13 comprises the small stair 41 of an annular, and the preferred heights of small stair 41 is 0.2 ~ 0.8mm.What describe in the manufacture method of the present embodiment and embodiment 1 is similar, just when knitted body 5 is still two ends loose mesh grid tubulose state, fixing and connecting device described in just first making, the outer face of short nut 11 protrudes from slightly the outer face of short sleeve 12 and forms small stair 41, braided wires stiff end 7 part be exposed to outside short sleeve 12 then relies on (just also on small stair 41) on the sidewall of short nut 11, after completing integral solder portion 13, then knitted body 5 is turned over, fixing and the connecting device of just one-step forming is made to be enclosed within knitted body 5, finally utilize known technology, the braided wires of the other end of knitted body 5 is also fixed, knitted body 5 is put into corresponding mould, the double plate shape of needs is formed by heat treated mode, as shown in Figure 6.Under small stair 41 makes braided wires stiff end 7 be exposed to the irradiation of laser beam more fully, laser beam can melt the expose portion of braided wires stiff end 7 more quickly and evenly, and the integral solder portion 13 processed like this is more regular also more firm.In order to form small stair 41, the length of short sleeve 12 is slightly less than the length of short nut 11, but does not need the length reducing short nut 11, also can not affect the intensity be threaded.Certainly, also the knitted body 5 only need fixing braided wires in its one end can be made, now can strut the mesh of one end of the fixed point free of knitted body 5, obtain enough working places, so that directly assemble and weld described fixing and connecting device in the inside of knitted body 5, need the inside first braided wires stiff end 7 being folded to knitted body 5 when assembling, after completing the making of introversive fixing and connecting device, heat treatment is shaped into dual disc stopper again.
Adopt the method be similar in embodiment 2, the occluder for left auricle of the embodiment 3 as shown in Fig. 8, Fig. 9 and Figure 10 can be made.Be easier to form thrombosis near left auricle, and thrombosis herein has very large direct harm, therefore, the thrombus source reducing occluder for left auricle has larger necessity.
Fixing and the connecting device described in this embodiment 3, also be enclosed in the inside of the knitted body 5 of occluder for left auricle completely, this is fixed and connecting device is connected with an outer face of knitted body, preferably, the outer face of knitted body 5 is smooth, has met the requirement of Clinical practice well.In the prior art, many braided wires stiff ends 7 concentrate the center being fixed on knitted body 5, even if such connecting device to be turned to the inside of knitted body 5, are also difficult to the crowded braided wires of the center of knitted body 5 lateral surface to flatten.On the contrary, the braided wires stiff end 7 of the present embodiment 3 can not concentrate on a central point, but the periphery of homodisperse short thread 11, this reduces the mutual obstruction between braided wires, therefore easier all braided wires by bending near short thread 11 flatten, and achieve the planarization of the outer face of knitted body 5.After the left atrial appendage occlusion apparatus implant into body of the present embodiment 3, introversive fixing and connecting device avoids evagination, achieve smooth outer face well, accelerate endotheliocyte to cover climbing of equipment surfaces, at utmost reduce thrombosis rate, reduce harmful metal ion to the release in blood, farthest reduce apparatus to the impact of left atrium blood flow, avoid the apparatus after implanting to hinder follow-up instrumentation more simultaneously.
In above multiple embodiment, short nut 11 can replace to threadless inner sleeve 24 as shown in figure 11, and knitted body 5 realizes threadless fixing and connecting device.Insert inner sleeve 24 with the connecting rod 21 of an auxiliary rod 22 and a distally bulb 23, form departing connection.The diameter of bulb 23 is less than the internal diameter of inner sleeve 24, and the diameter of auxiliary rod 22 and the diameter sum of bulb 23 are greater than the internal diameter of inner sleeve 24.Before connecting rod 21 connects with knitted body 5, first the bulb 23 of connecting rod 21 far-end is passed inner sleeve 24, then insert auxiliary rod 22, then connecting rod 21 and knitted body 5 are joined together.Now, connecting rod 21 and auxiliary rod 22 are inserted among inner sleeve 24 simultaneously, then connecting rod 21 can not proximally be freed.If extract auxiliary rod 22 out inner sleeve 24, then connecting rod 21 can freely be freed.
The advantage of medical apparatus and instruments of the present invention is: 1, the lateral surface of the knitted body of implantation instrument is given prominence to without outstanding or reduction, preferably, realize knitted body after implant into body, to remain outer surface be similar to burnishing surface or little outstanding, the climbing of endothelium of accelerating medical apparatus surface is covered, at utmost reduce thrombosis rate, reduce harmful metal ion to the release in blood, farthest reduce the impact that medical apparatus and instruments flows on blood of human body, avoid the medical apparatus and instruments implanted to hinder the operation of subsequent instrument simultaneously.2, product structure and Making programme simplify, and reduce fabrication error, are conducive to improving conforming product rate.
The foregoing is only preferred embodiment of the present invention, not in order to limit the present invention, all any amendments done within the spirit and principles in the present invention, equivalent replacement and improvement etc., all should be included within protection scope of the present invention.
Claims (10)
1. the medical apparatus and instruments for interventional therapy, comprise at least one knitted body, at least one knitted body described is made up of many braided wires, at least one braided wires among described many braided wires has braided wires stiff end, it is characterized in that, also comprise a fixing and connecting device, described fixing and connecting device comprises an inner sleeve and a trocar sheath, described inner sleeve is fixed on the inside of described trocar sheath, described braided wires stiff end is fixed between the outer circumference surface of described inner sleeve and the inner peripheral surface of described trocar sheath, described inner sleeve is complete hollow, the two ends of described inner sleeve are all open, the material at least partially of described braided wires stiff end melts and is filled in the gap between inner sleeve and trocar sheath, at least one circle of laser beam continuous welding, at described braided wires stiff end and overallly between described inner sleeve and trocar sheath forms annular weld part.
2., as claimed in claim 1 for the medical apparatus and instruments of interventional therapy, it is characterized in that: the length of described inner sleeve is substantially equal with the length of trocar sheath.
3., as claimed in claim 1 for the medical apparatus and instruments of interventional therapy, it is characterized in that: the difference of the internal diameter of described trocar sheath and the external diameter of described inner sleeve, substantially equal the twice of the cross section maximum gauge of described braided wires.
4., as claimed in claim 1 for the medical apparatus and instruments of interventional therapy, it is characterized in that: described inner sleeve has female thread.
5., as claimed in claim 4 for the medical apparatus and instruments of interventional therapy, it is characterized in that: the length of described inner sleeve is 1 ~ 2 millimeter, and described female thread runs through whole inner sleeve.
6., as claimed in claim 1 for the medical apparatus and instruments of interventional therapy, it is characterized in that: described braided wires stiff end is evenly distributed on the outer circumference surface of described inner sleeve.
7. as claimed in claim 1 for the medical apparatus and instruments of interventional therapy, it is characterized in that: in the outer face of described inner sleeve and described trocar sheath, described braided wires stiff end and overallly between described inner sleeve and trocar sheath forms annular weld part.
8. as claimed in claim 7 for the medical apparatus and instruments of interventional therapy, it is characterized in that: the step that between described trocar sheath and described inner sleeve one of described weld part is annular is formed, the height of described step is 0.2 ~ 0.8 millimeter, and described weld part is formed by laser weld.
9. as claimed in claim 1 for the medical apparatus and instruments of interventional therapy, it is characterized in that: described fixing and connecting device is positioned at the inside of at least one knitted body described.
10. as claimed in claim 1 for the medical apparatus and instruments of interventional therapy, it is characterized in that: described fixing and connecting device is connected with an outer face of one of them knitted body, and described outer face is smooth.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210389823.9A CN102908174B (en) | 2012-10-15 | 2012-10-15 | Medical instrument for interventional therapy |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210389823.9A CN102908174B (en) | 2012-10-15 | 2012-10-15 | Medical instrument for interventional therapy |
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| Publication Number | Publication Date |
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| CN102908174A CN102908174A (en) | 2013-02-06 |
| CN102908174B true CN102908174B (en) | 2015-03-25 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201210389823.9A Ceased CN102908174B (en) | 2012-10-15 | 2012-10-15 | Medical instrument for interventional therapy |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10813647B2 (en) | 2016-06-15 | 2020-10-27 | Lifetech Scientific (Shenzhen) Co., Ltd | Left atrial appendage occluder |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9744033B2 (en) | 2011-04-01 | 2017-08-29 | W.L. Gore & Associates, Inc. | Elastomeric leaflet for prosthetic heart valves |
| US9554806B2 (en) | 2011-09-16 | 2017-01-31 | W. L. Gore & Associates, Inc. | Occlusive devices |
| US11911258B2 (en) | 2013-06-26 | 2024-02-27 | W. L. Gore & Associates, Inc. | Space filling devices |
| CN105796148B (en) * | 2014-12-31 | 2018-06-05 | 先健科技(深圳)有限公司 | Occluder for left auricle |
| CA2986047C (en) | 2015-05-14 | 2020-11-10 | W. L. Gore & Associates, Inc. | Devices and methods for occlusion of an atrial appendage |
| CN106175867A (en) * | 2016-08-30 | 2016-12-07 | 上海心玮医疗科技有限公司 | A kind of occluder for left auricle and preparation method thereof |
| US11812968B2 (en) | 2017-05-10 | 2023-11-14 | Lifetech Scientific (Shenzhen) Co. Ltd. | Left atrial appendage occluder |
| CN108969030B (en) * | 2017-06-02 | 2022-01-07 | 上海佐心医疗科技有限公司 | Medical device |
| CN107440761A (en) * | 2017-07-20 | 2017-12-08 | 上海心玮医疗科技有限公司 | A kind of plugging device with embedded steel bushing |
| US11173023B2 (en) | 2017-10-16 | 2021-11-16 | W. L. Gore & Associates, Inc. | Medical devices and anchors therefor |
| CN109745149B (en) * | 2017-11-07 | 2024-09-20 | 深圳市健心医疗科技有限公司 | Heart valve anchoring device and heart valve |
| CN110680415B (en) * | 2019-09-20 | 2024-05-17 | 珠海丽笙医疗科技有限公司 | Cladding type plugging device |
| CN112244927B (en) * | 2019-11-04 | 2025-07-15 | 深圳市科奕顿生物医疗科技有限公司 | Intraluminal implantable medical devices |
| CN116763384A (en) * | 2023-05-23 | 2023-09-19 | 上海玮启医疗器械有限公司 | An anticoagulant-coated left atrial appendage occlusion device and its preparation method |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN201200495Y (en) * | 2008-04-21 | 2009-03-04 | 先健科技(深圳)有限公司 | Plugging device |
| CN101450018A (en) * | 2007-11-28 | 2009-06-10 | 王涛 | Recoverable valve bracket |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10338702B9 (en) * | 2003-08-22 | 2007-04-26 | Occlutech Gmbh | Occlusioninstrument |
| DE102004012351A1 (en) * | 2004-03-11 | 2005-09-29 | pfm Produkte für die Medizin AG | Device for recanalizing a cavity, organ or vessel |
-
2012
- 2012-10-15 CN CN201210389823.9A patent/CN102908174B/en not_active Ceased
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101450018A (en) * | 2007-11-28 | 2009-06-10 | 王涛 | Recoverable valve bracket |
| CN201200495Y (en) * | 2008-04-21 | 2009-03-04 | 先健科技(深圳)有限公司 | Plugging device |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10813647B2 (en) | 2016-06-15 | 2020-10-27 | Lifetech Scientific (Shenzhen) Co., Ltd | Left atrial appendage occluder |
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| CN102908174A (en) | 2013-02-06 |
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