CN102830221B - Mixing device of automatic biochemical analyzer - Google Patents
Mixing device of automatic biochemical analyzer Download PDFInfo
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- CN102830221B CN102830221B CN201210317873.6A CN201210317873A CN102830221B CN 102830221 B CN102830221 B CN 102830221B CN 201210317873 A CN201210317873 A CN 201210317873A CN 102830221 B CN102830221 B CN 102830221B
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- stepper motor
- cuvette
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- rotation
- driving
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- 230000000694 effects Effects 0.000 claims description 4
- 238000005461 lubrication Methods 0.000 claims description 2
- 239000003153 chemical reaction reagent Substances 0.000 abstract description 11
- 238000003756 stirring Methods 0.000 abstract description 10
- 238000001514 detection method Methods 0.000 abstract 2
- 238000000149 argon plasma sintering Methods 0.000 abstract 1
- 238000012864 cross contamination Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 description 3
- 239000000203 mixture Substances 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000001050 lubricating effect Effects 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
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Abstract
The invention relates to a mixing device of an automatic biochemical analyzer, which relates to the technical field of the automatic biochemical analyzer. The mixing device solves the technical disadvantage that in the prior art, a stirring rod is used for directly inserting in a cuvette for rotating with high speed to mix a sample and a reagent to obtain the detection results which have errors easily, the mixing device is characterized in that a cuvette holding groove used for holding the cuvette is provided below a reaction plate, corresponding to the position of a cuvette cup hole, a connecting rod is connected at the bottom of the cuvette holding groove, a driving mechanism is connected to the bottom of the connecting rod, and the driving mechanism is mainly composed of a rotation stepping motor used for driving the rotation of the connecting rod and a lifting-up mechanism used for driving the elevation of the connecting rod. According to the invention, the lifting and rotation of the cuvette holding groove can be used for holding the cuvette filled with the sample and the reagent from a fixed hole on the reaction plate, then the rotary stirring is carried out, relative to a current stirring mode, the sample and the reagent can be mixed without contact with a solution, thereby the cross contamination of the solution can be avoided, bubbles can not generate, the light scattering caused by bubble can be avoided, and the detection result has high accuracy.
Description
Technical field
The present invention relates to automatic clinical chemistry analyzer technical field, be specifically related to automatic clinical chemistry analyzer inside for the sample in contrast colors cup and the well-mixed device aspect of reagent.
Background technology
Automatic clinical chemistry analyzer is one of important analysis instrument often used in clinical examination, and it is by measuring various biochemical indicator to the analysis of blood or other body fluid, to give diagnosis and to determine that patient's state of an illness provides scientific basis.
In automatic clinical chemistry analyzer, mixing arrangement is required.The effect of mixing arrangement makes the sample in cuvette and reagent fully mix.
The mixing arrangement adopted in current automatic clinical chemistry analyzer all adopts stirring apparatus, and stirring rod directly inserts High Rotation Speed after cuvette, makes sample and reagent fully mix.This mode can make in cuvette and produce bubble, and the liquid that stirring rod adheres to can cause cross pollution, and these 2 shortcomings all can make testing result produce error.Common improving one's methods is added non-sticking lining to stirring rod or is added an independent Butterworth Hatch to stirring rod, and these methods both added cost, can not eliminate error completely again.
Summary of the invention
In sum, the object of the invention is to solve existing employing stirring rod directly insert cuvette after the mode of the High Rotation Speed mode of carrying out mixing sample and reagent there is the technical deficiency that error easily appears in testing result, and the mixing arrangement of a kind of automatic clinical chemistry analyzer proposed.
For solving technical matters proposed by the invention, the technical scheme adopted is: a kind of mixing arrangement of automatic clinical chemistry analyzer, it is characterized in that: comprise being located at below reaction tray and be provided with the hypanthium groove for lifting cuvette with colorimetric cup aperture position correspondence position, the bottom of hypanthium groove is provided with connecting link, is connected with driving mechanism bottom connecting link; Described driving mechanism is primarily of driving the rotation stepper motor of connecting link rotation and driving the lifting body of connecting link lifting to form.
Described connecting link is directly fixedly connected with rotation stepper motor; Lifting body is located at bottom rotation stepper motor.
Described lifting body includes the guiding mechanism that is flexibly connected rotation stepper motor and for the cylinder of jacking rotation stepper motor or linear electric motors.
Described lifting body includes the guiding mechanism and jacking stepper motor that are flexibly connected rotation stepper motor; Described jacking stepper motor is connected with rotation stepper motor by screw rod.
Described driving mechanism is located at constant temperature enclosure outside, connecting link be provided with constant temperature enclosure bottom the seal of through hole lubrication and seal offered.
The degree of depth of described hypanthium groove is 1/2 to 1/5 of cuvette height, bore be with cuvette coincide square.
Described lifting body is located between connecting link and rotation stepper motor; Described lifting body comprises a screw rod be connected with connecting link and a nut be socketed on screw rod; Described screw rod bottom is docked with the driving shaft activity of rotation stepper motor by not rounded connection-peg, and nut is relative with rotation stepper motor to be fixedly connected with.
Beneficial effect of the present invention is: the present invention adopts the upper act of hypanthium groove and rotation to be held up from the fixed orifice reaction tray by the cuvette that sample and reagent are housed, then Stirring is carried out, relative to existing alr mode, when biased sample and reagent, do not need to contact solution, avoid the cross pollution of solution; Can not produce bubble, avoid the scattering of bubble to light, testing result accuracy rate is high simultaneously.
Accompanying drawing explanation
Structural representation when Fig. 1 is before embodiments of the invention 1 hypanthium groove has lifted cuvette;
Fig. 2 is the structural representation of embodiments of the invention 1 hypanthium groove when having lifted cuvette;
Structural representation when Fig. 3 is before embodiments of the invention 2 hypanthium groove has lifted cuvette;
Fig. 4 is the structural representation of embodiments of the invention 2 hypanthium groove when having lifted cuvette.
Embodiment
Below in conjunction with accompanying drawing and the preferred two kinds of embodiments of the present invention, structure of the present invention is further described.
Embodiment 1
Shown in seeing figures.1.and.2, constant temperature enclosure 1 inside of automatic clinical chemistry analyzer is provided with reaction tray 2, reaction tray 2 is also known as traffic cycle, reaction tray 2 is circumferentially distributed with several colorimetric cup aperture, a cuvette 3 can be placed in each colorimetric cup aperture, colorimetric cup aperture in reaction tray 2 is circular, and the cup body of cuvette 3 and colorimetric cup aperture hole wall clearance fit, cuvette 3 is suspended in reaction tray 2 by the outer that opening part turns up.
The present invention includes hypanthium groove 4, connecting link 5 and driving mechanism 6.Hypanthium groove 4 be located at below reaction tray 2 with colorimetric cup aperture position correspondence position, the degree of depth of hypanthium groove 4 is 1/2 to 1/5 of cuvette 3 height, bore be with cuvette coincide square, be socketed with cuvette 3 in order to unspecified angle realizes hypanthium groove 4, the bore of hypanthium groove 4 can be funnel-form, hypanthium groove 4 for upwards having lifted cuvette 3, after cuvette 3 is suitably lifted, depart from the restriction of the colorimetric cup aperture in reaction tray 2, can free rotation.Connecting link 5 top is fixedly connected with the bottom centre of hypanthium groove 4; driving mechanism 6 is connected again bottom connecting link 5; it is outside that driving mechanism 6 is preferably located at constant temperature enclosure 1; connecting link 5 connects driving mechanism 6 after the diapire of constant temperature enclosure 1 is drawn; be full of not volatile lubricating fluid between the diapire fairlead of connecting link 5 and constant temperature enclosure 1, neither affect the impermeability that connecting link 5 rotates and moves up and down and protect constant temperature enclosure.Driving mechanism 6 is primarily of driving the rotation stepper motor 61 of connecting link 5 rotation and driving the lifting body 62 of connecting link 5 lifting to form.
Described connecting link 5 is directly fixedly connected with rotation stepper motor 61, and when rotation stepper motor 61 works, connecting link 5 forward rotation or oppositely rotation, that is to say and drive the rotation of hypanthium groove 4; Lifting body 62 is located at bottom rotation stepper motor 61, and lifting body 62 includes the guiding mechanism 621 that is flexibly connected rotation stepper motor 61 and for the cylinder of jacking rotation stepper motor 61 or linear electric motors 622; In specific implementation process, lifting body 62 can certainly adopt guiding mechanism and jacking stepper motor to form, and jacking stepper motor is connected with rotation stepper motor 61 by screw rod.
The course of work of the present invention is: under the driving of reaction tray 2, the cuvette 3 adding sample and reagent is gone to position directly over hypanthium groove 4, then lifting body 62 performs jacking operation, rotation stepper motor 61, connecting link 5 and hypanthium groove 4 rise, hypanthium groove 4 by cuvette 3 outer from the colorimetric cup aperture of reaction tray 2 depart from fixing after, rotation stepper motor 61 fast rotational, cuvette 3 rotation is fast driven by connecting link 5 and hypanthium groove 4, solution in cuvette 3 is flowed fast, thus sample and reagent are fully mixed; After mixing, rotation stepper motor 61 stops the rotation lentamente, makes the angle before cuvette 3 recovery rotation; Then, lifting body 62 resets, and hypanthium groove 4 declines, and cuvette 3 returns to be fixed with the colorimetric cup aperture of reaction tray 2, and rotated by reaction tray 2 and take cuvette 3 away, operation completes.
Embodiment 2
With reference to shown in Fig. 3 and Fig. 4, when cuvette 3 xsect is circular, consider the Cost Problems of lifting body 62 ', described lifting body 62 ' is located between connecting link 6 and rotation stepper motor 61; Described lifting body 62 ' comprises a screw rod 621 ' be connected with connecting link 5 and a nut 622 ' be socketed on screw rod 621 '; Described screw rod 621 ' bottom is docked with the driving shaft activity of rotation stepper motor 61 by not rounded connection-peg 623 ', and nut 622 ' is relative with rotation stepper motor 61 to be fixedly connected with.
In the present embodiment, the principle of work of lifting body 62 ' is: as rotation stepper motor 61 rotate forward time, screw rod 621 ' is with under the cooperation of nut 622 ', connecting link 5 rises, after the threaded portion of screw rod 621 ' produces completely from nut 622 ', threaded portion loses with nut and coordinates, when rotation stepper motor 61 continues to rotate forward, connecting link 5 stops rising, and hypanthium groove 4 has lifted cuvette 3 rotation; When rotation stepper motor 61 reverses, the threaded portion of screw rod 621 ' reenters in nut 622 ', and connecting link 5 advances downwards, and cuvette 3 declines and resets, and screw rod 621 ' threaded portion without the need to coming off from nut.
Claims (5)
1. a mixing arrangement for automatic clinical chemistry analyzer, is characterized in that: comprise being located at below reaction tray and be provided with the hypanthium groove for lifting cuvette with colorimetric cup aperture position correspondence position, and the bottom of hypanthium groove is provided with connecting link, is connected with driving mechanism bottom connecting link; Described driving mechanism is primarily of driving the rotation stepper motor of connecting link rotation and driving the lifting body of connecting link lifting to form; Described lifting body is located between connecting link and rotation stepper motor; Described lifting body comprises a screw rod be connected with connecting link and a nut be socketed on screw rod; Described screw rod bottom is docked with the driving shaft activity of rotation stepper motor by not rounded connection-peg, and nut is relative with rotation stepper motor to be fixedly connected with.
2. a mixing arrangement for automatic clinical chemistry analyzer, is characterized in that: comprise being located at below reaction tray and be provided with the hypanthium groove for lifting cuvette with colorimetric cup aperture position correspondence position, and the bottom of hypanthium groove is provided with connecting link, is connected with driving mechanism bottom connecting link; Described driving mechanism is primarily of driving the rotation stepper motor of connecting link rotation and driving the lifting body of connecting link lifting to form; Described connecting link is directly fixedly connected with rotation stepper motor; Lifting body is located at bottom rotation stepper motor; Described driving mechanism is located at constant temperature enclosure outside, connecting link be provided with constant temperature enclosure bottom the seal of through hole lubrication and seal offered.
3. the mixing arrangement of a kind of automatic clinical chemistry analyzer according to claim 2, is characterized in that: described lifting body includes the guiding mechanism that is flexibly connected rotation stepper motor and for the cylinder of jacking rotation stepper motor or linear electric motors.
4. the mixing arrangement of a kind of automatic clinical chemistry analyzer according to claim 2, is characterized in that: described lifting body includes the guiding mechanism and jacking stepper motor that are flexibly connected rotation stepper motor; Described jacking stepper motor is connected with rotation stepper motor by screw rod.
5. the mixing arrangement of a kind of automatic clinical chemistry analyzer according to claim 2, is characterized in that: the degree of depth of described hypanthium groove is 1/2 to 1/5 of cuvette height, bore be with cuvette coincide square.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210317873.6A CN102830221B (en) | 2012-08-31 | 2012-08-31 | Mixing device of automatic biochemical analyzer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210317873.6A CN102830221B (en) | 2012-08-31 | 2012-08-31 | Mixing device of automatic biochemical analyzer |
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| Publication Number | Publication Date |
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| CN102830221A CN102830221A (en) | 2012-12-19 |
| CN102830221B true CN102830221B (en) | 2015-05-27 |
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| CN201210317873.6A Active CN102830221B (en) | 2012-08-31 | 2012-08-31 | Mixing device of automatic biochemical analyzer |
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Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104076157B (en) * | 2014-07-15 | 2015-12-02 | 中国科学院苏州生物医学工程技术研究所 | A kind of rocking equipment |
| CN104555280B (en) * | 2014-12-31 | 2017-01-18 | 江苏安德信超导加速器科技有限公司 | Automatic sample changing device in radiation environment |
| CN105373763B (en) * | 2015-12-21 | 2018-04-24 | 艾康生物技术(杭州)有限公司 | Identity information reading device |
| CN105628945B (en) * | 2015-12-21 | 2018-02-02 | 利多(香港)有限公司 | Container rotation device and container rotation method |
| US10473650B2 (en) | 2017-03-01 | 2019-11-12 | Leadway (Hk) Limited | Reagent mixing and conveying device and reagent mixing method |
| US10112781B2 (en) | 2017-03-01 | 2018-10-30 | Leadway (Hk) Limited | Container autorotation device and container autorotation method |
| CN110376393B (en) * | 2019-08-21 | 2023-05-30 | 东软威特曼生物科技（沈阳）有限公司 | Reaction disc with solid direct-heating structure and full-automatic biochemical analyzer thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2825331B2 (en) * | 1990-09-21 | 1998-11-18 | 株式会社日立製作所 | Automatic analyzer |
| CN1384361A (en) * | 2001-04-27 | 2002-12-11 | 刘岩 | Separate multi-channel biochemical analyzer |
| JP4185859B2 (en) * | 2003-12-19 | 2008-11-26 | 株式会社日立ハイテクノロジーズ | Automatic analyzer |
| JP4110101B2 (en) * | 2004-01-28 | 2008-07-02 | 株式会社日立ハイテクノロジーズ | Automatic analyzer |
| CN102419375B (en) * | 2011-08-24 | 2013-08-28 | 四川迈克生物科技股份有限公司 | Full-automatic chemoluminescence immunoassay analyzer |
| CN202837297U (en) * | 2012-08-31 | 2013-03-27 | 深圳市尚荣医疗股份有限公司 | Mixing device of fully automatic biochemical analyzer |
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