CN102784339B - Medicament for treating pulmonary tuberculosis by combined chemotherapy with traditional Chinese medicine Fuying and preparation method - Google Patents
Medicament for treating pulmonary tuberculosis by combined chemotherapy with traditional Chinese medicine Fuying and preparation method Download PDFInfo
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Abstract
The invention relates to a medicament for treating pulmonary tuberculosis by combined chemotherapy with traditional Chinese medicine Fuying and a preparation method; in the medicament, a traditional Chinese medicine of Fuying No. I comprises gecko, donkey-hide gelatin, stemona, adenophora stricta, radix ophiopogonis, prunella vulgaris, radix scrophulariae, fritillaria thun-bergli, cortex lycii radicis, bletilla striata, picrorhiza scrophulariiflora pennell, rehmanniae radix, and anemarrhena, and is mainly used for expelling evil and nourishing yang; a traditional Chinese medicine of Fuying No. II comprises codonopsis pilosula, Chinese yam, poria cocos, schisandra chinensis, radix rehmanniae preparata, angelica, caulis spatholobi, gentrin knotweed, bighead atractylodes rhizome, and radix astragali, and is mainly used for strengthening the body resistance and nourishing body; western medicines participating the combined chemotherapy comprise: streptomycin injections, isoniazid tablets, rifampin, and pyrazinamide capsules; during the combined chemotherapy with the medicines, not only stable therapeutic effect on pulmonary tuberculosis is realized, but also nourishing treatment effect on patients with hepatopathy is realized; during preparation, geckoes are grinded into fine powder, and fried with donkey-hide gelatin; then the other medicines are cleaned, dried, pulverized, and grinded into fine powder; the fine powder is sieved by a No. 6 sieve to obtain a pulvis; the pulvis is packaged into bags to obtain the Fuying No. I. During the preparation of the Fuying No. II, the medicines are also selected, cleaned, pulverized, and grinded into fine powder; the fine powder is sieved by a No. 6 sieve to obtain a pulvis; the pulvis is packaged into bags to obtain the Fuying No. II. During treatment, the traditional Chinese medicine Fuying is combined with western medicines for administration.
Description
[technical field]
The present invention relates to a kind of Chinese medicine and hold up the win phthisical medicine of combination chemotherapy and preparation method.
[background technology]
Tuberculosis, the traditional Chinese medical science claims " consumptive disease illness ", is commonly called as tuberculosis, this disease is to have communicable chronic expendable illness, be mainly cough, spitting of blood, hectic fever, night sweat and health are become thin gradually etc. is its Clinical symptoms.How because having a delicate constitution, insufficiency of vital energy and blood.Consumptive disease is invaded due to lung by worm.Along with the reach of science, there is a large amount of Newer Antibuberculotics, can obtain medical treatment or cure through rationalizing the most patients for the treatment of, but still have considerable patient's focus to join and one or more cavities.In long-term chemotherapy, by there will be new pathology, produce a toxic reaction to a drug.Many hospitals are in phthisical chemotherapy, and what mostly adopt is Western medicine chemotherapy, but Western medicine is in long-term chemotherapy, will develop immunity to drugs, and has hindered further medication, brought huge economic pressures and stress to patient and family.
[summary of the invention]
Object of the present invention will provide a kind of Chinese medicine to hold up the win phthisical medicine of combination chemotherapy and preparation method exactly, this medicine holds up win Western medicine to carry out combined chemotherapy for pulmonary tuberculosis with Chinese medicine, what is called is held up win, it is to get " internal diameter " " osteanabrosis; imperial palace is sagged; gas is full in the heart, the inconvenience of panting, interior pain are drawn shoulder item, body heat, de-Nei Po popliteal " containing view.
Win is: become thin, weak meaning, hold up as winning and help, nourish.
Hold up win implication to be: to nourish and subsidize the physique of becoming thin, make it strong, healthy meaning.The present invention is coupling group by the case of traditional Chinese and western medicine drug combination, and the simple medication case taking Western medicine chemotherapy, as chemotherapy group, is now taken out chemotherapy data from medical record patient.(1) 6 months persons of all course of therapy, the normal person of liver function before treatment.(2) x-ray rabat has reversible pathology, and focus is added and is more than or equal to a side lung 1/3 lung page, or without empty person.(3) two groups of case basic conditions are roughly the same, now from medical record, propose 240 routine lungers, and disease is divided into two groups at random, hold up win chemotherapeutics group to claim coupling group for one group for containing, and another group is alone chemicals group.
Wherein coupling group 120 examples, male 68 examples, female's 52 examples, the range of age 20～60 years old, 40 years old mean age; Just control 55 examples, control again 65 examples; III type 106 examples, II type 14 examples, phlegm bacterium is coated with positive 57 examples.
Chemotherapy group 120 examples, male 72 examples, female's 48 examples; The range of age 20～60 years old, 39 years old mean age; Just control 58 examples, control again 62 examples; III type 102 examples, II type 18 examples, phlegm bacterium is coated with positive 58 examples.
In therapeutic process, coupling group carries out strengthening vital QI to eliminate pathogenic factors with Chinese medicine of the present invention is principle for the treatment of, Chinese medicine of the present invention also claims to hold up to win treats, the present invention will hold up among win medicine to be divided into holding up to win No. I and hold up and win No. II, wherein hold up that to win be mainly for No. I taking eliminating evil as main, newly call to be eliminating evilly exactly: " anti-consumptive disease desinsection, enriching yin training sky ";
Hold up and win No. II taking righting as main, so-called righting is exactly: nourish qi-restoratives.
Hold up the combination ingredient of win to be described further with regard to Chinese medicine below:
1, hold up and win No. I, formed by following taste medicine and weight ratio:
15～25 grams of 15～20 grams of tubers of stemona of 8～17 grams of donkey-hide gelatin of gekko
10～15 grams of the root of straight ladybell 15～25 grams of Spica Prunellaes, 15～25 grams of tubers of dwarf lilyturf
15～20 grams of 10～15 grams of Root-bark of Chinese Wolfberry of 15～20 grams of bulbs of fritillary of radix scrophulariae
10～15 grams of the bletilla striatas
In the machine of its compatibility, be
Gekko levigation, due to salty flat, is lung stomach warp, can, by lung qi, help kidney yang, determines the sound of sth. throbbing or bursting and coughs, benefiting essence-blood.
Donkey-hide gelatin: Gan Ping, return lung, liver, kidney channel, tonify the blood and arrest bleeding, nourishing Yin and moistening lung.
The tuber of stemona: taste is sweet, bitter, put down, return lung, warp, moisten the lung and relieve the cough, desinsection.
The root of straight ladybell: taste is sweet, be slightly cold, attach to the lung and stomach meridians, clearing lung and nourishing yin, reinforcing stomach reg fluid.
The tuber of dwarf lilyturf: sweet, the micro-hardship of taste, tremble with fear, return lung, the heart, stomach warp, moistening lung, yin-nourishing, reinforcing stomach reg fluid, relieving restlessness clears away heart-fire.
Spica Prunellae: taste bitter, acrid, cold, return liver, gallbladder channel, clearing away the liver-fire, loose strongly fragrant whole, step-down.
Radix scrophulariae: sweet-bitter flavor, salty-cold, return lung, stomach kidney, heat-clearing, removing toxic substances, yin-nourishing.
Unibract Fritillary Bulb: bitter, hardship, be slightly cold, return lung the heart channel of Hang-Shaoyin, preventing phlegm from forming and stopping coughing, heat-clearing dissipating bind.
Root-bark of Chinese Wolfberry: taste is sweet, light, tremble with fear, return lung, kidney channel, cool blood to move back steaming, clearing away lung-heat.
The bletilla striata: bitter but sweet flavor, puckery, be slightly cold, return lung, liver, stomach warp, astringing to arrest bleeding, clearing lung-heat myogenic.
Above-mentioned each taste medicine, by monarch drug in a prescription, ministerial drug, adjutant] do further to analyze.
In we, monarch drug in a prescription is that gekko powder is fried donkey-hide gelatin, and wherein gekko plays the effect of " treating YIN within YANG ", and donkey-hide gelatin plays and enriches blood, hemostasis, nourishing Yin and moistening lung, the two closes rear effect of playing altogether tonifying lung benefit essence effectively to kill day tubercule bacillus.In addition ministerial drug sand, ginseng, the tuber of dwarf lilyturf, bletilla, the tuber of stemona can help Yin nourishing and lung moistening, desinsection, tonifying lung astringing to arrest bleeding, pulmonary tuberculosis is had to certain effect; Its adjutant be river owe mother, the dried rhizome of rehmannia, soothing the liver, regulate the flow of vital energy, tubercule bacillus had to certain restraining effect; Its make medicine be Root-bark of Chinese Wolfberry, Rhizoma Picrorhizae, can clearind deficient heat, to pulmonary tuberculosis heating] night sweat has certain curative effect.
From above analysis, hold up and win I principle of reatment taking " eliminating evil enriching yin " as principle for the treatment of, the roman thought of prescription, can reach very fast Healing to pulmonary tuberculosis cavity, effectively kill a day tubercule bacillus, tubercule bacillus is had certain restraining effect, pulmonary tuberculosis heating, night sweat are had to very fast therapeutic action, roman formula is rigorous, gives full play to effect that monarch in prescription, minister, assistant make, and does not have the untoward reaction such as restriction or checking relation in five elements, the mutual-detoxication.
Further analyze to hold up below and win No. II, its composition and dosage thereof are:
15～25 grams of Radix Codonopsis, 15～30 grams of Chinese yams, 15～20 grams, Poria cocos, 10～12 grams, shizandra berry.
10～25 grams, cultivated land, 8～15 grams of Radix Angelicae Sinensis, 10～15 grams of Yunnan Caulis Spatholobis, 10～15 grams of tiger battles.
10～15 grams of the bighead atractylodes rhizomes, 15～25 grams of the Radixs Astragali.
In the machine of its compatibility, be:
Radix Codonopsis: taste is sweet, equal, return the spleen channel, by beneficial gas, promote the production of body fluid and nourish blood.
Chinese yam: taste is sweet, put down, return spleen lung kidney channel, supplementing QI and nourishing YIN, tonifying spleen, lung kidney.
Poria cocos: sweet, light flat, the thoughts of returning home spleen of taste, kidney channel, promoting diuresis to eliminate damp pathogen, invigorating the spleen.
Shizandra berry: taste is diligent, wet, be lung, kidney, the heart channel of Hang-Shaoyin, holds back liver nourshing kidney, the arrest sweating that promotes the production of body fluid, tranquillizing by calming the heart.
Cultivated land: taste is sweet, micro-wets, returns liver, kidney channel, nourishing the blood and yin, benefit lean marrow.
Radix Angelicae Sinensis: taste is sweet, pungent, warm, return liver heart spleen, enriches blood, invigorates blood circulation, pain relieving, moistening lung.
Yunnan Caulis Spatholobi: bitter, micro-sweet, warm, return Liver Channel, blood to enrich blood, stimulate the circulation of the blood and cause the muscles and joints to relax.
Tiger battle: bitter, tremble with fear, return liver, courage, lung channel, invigorate blood circulation, heat-clearing, preventing phlegm from forming and stopping coughing.
The bighead atractylodes rhizome: taste is sweet, sweet, warm, return spleen lung channel, tonifying Qi, beneficial gas, myogenic, Li Shui.
The Radix Astragali: the sweet tepor of taste, return spleen, lung channel, tonifying Qi, beneficial gas, myogenic, Li Shui.
Above-mentioned each taste medicine, by monarch drug in a prescription, ministerial drug, adjutant, make medicine do a step analysis.
Monarch drug in a prescription: the merit taking Radix Codonopsis, the Radix Astragali, Chinese yam as group, powerful tonifying Qi, levelling human body immune function.
Ministerial drug: can nourish blood taking cultivated land, Yunnan Caulis Spatholobi, Radix Angelicae Sinensis, the bighead atractylodes rhizome as group, enrich blood, invigorate blood circulation, vasodilation, improve microcirculation, strengthen hole tuberculosis drug effect fruit.
Adjutant is taking Poria cocos, tiger battle as group, can invigorating the spleen, heat-clearing, reduce phlegm, calm the nerves.Making medicine is shizandra berry, can promote the production of body fluid arrest sweating, cough-relieving.
Holding up No. II, win, principle of reatment from above analysis is principle for the treatment of for " righting nourishing ".Be to consist of roman thought, align in addition in addition body, immunity function, improves immunity of organisms, gives full play to the effect of medicine, effectively kills tubercule bacillus, thereby improves curative effect.Because formula is careful, give full play to monarch, minister, help, make the effect of each medicine, there is not the untoward reaction of the mutual-detoxication, restriction or checking relation in five elements.
Another object of the present invention is its preparation method.
Describe in detail below and hold up win No. I and hold up the preparation method who wins No. II.
Hold up and win No. I:
When preparation, first gekko pulverization and donkey-hide gelatin are decocted to stir-fry, more each taste medicine is cleaned, dries, pulverized, pulverization, sieves into pulvis after No. 6, is packaged into bag.
Hold up and win No. II:
Produce to hold up and win when II, equally each medicine selected, clean, dried, pulverizing, pulverization, cross and sieve into pulvis, packaging, one-tenth bag for No. 6.
For making the present invention obtain curative effect and the function of giving full play to combined chemotherapy better, now the title of Western medicine and consumption are narrated:
Streptomycin sulphate injection liquid, consumption is with 0.73 gram～0.9 gram of intramuscular injection once a day;
Isoniazid tablets: consumption is every day three times, each 0.2～0.5 gram;
Rifampin: consumption is every day three times, each 0.3～0.5 gram;
Pyrazinamide capsule: consumption is every twice-daily, takes 1～3 gram after the meal.
Now describe the pharmacy mechanism of each taste Western medicine in detail:
Key mycin injection liquid:
For the halogen glucoside antibiotic of wide spectrum, tubercule bacillus is had to powerful bacteriostastis, under alkaline environment, kill tubercule bacillus effect strong, be " half bactericide ".
The mechanism of action: disturb the synthetic of tubercule bacillus protein and reach bacterium effect processed.
Rifampin: low agriculture degree is antibacterial, high density sterilization has cross-film ability, and target enzyme is had to stronger avidity, can enter in cell and play germicidal action, because the vigorous tuberculosis flora of metabolism inside and outside its cell all has germicidal action, therefore " full bactericide ".
Isoniazid tablets:
1, the required burning reductase enzyme of anti-bacteria, thereby anti-bacteria metabolism.
2, acid and alkali, alkali environmental influence, have germicidal action to the tubercule bacillus inside and outside cell, particularly eugonic breeding bacterium effect strong " full bactericide ".
Pyrazinoic acid amide:
Only limit in cell, and be " half bactericide " under sour environment.
The present invention is due to blending the east and the west, and combined chemotherapy pulmonary tuberculosis, obtains good therapeutic effect.
In the lunger to numerous, also have some not only to suffer from pulmonary tuberculosis, also suffers from the patient of hepatopathy, if alone chemotherapy group (being Western medicine) chemotherapy can only have good therapeutic effect to pulmonary tuberculosis, but inoperative to hepatopathy, and the present invention has taked Chinese medicine to hold up win to carry out the phthisical while of combination chemotherapy to suffering from the patient of hepatopathy, also patient is played to dual curative effect.
[specific embodiment]
The present invention below combines with best compatibility, as following examples:
Hold up and win No. I, formed by following taste medicine and weight ratio:
18 grams of 20 grams of the root of straight ladybell of 18 grams of tubers of stemona of 10 grams of donkey-hide gelatin of gekko levigation
12 grams of 18 grams of bulbs of fritillary of 12 grams of radix scrophulariaes of 20 grams of Spica Prunellaes tuber of dwarf lilyturf
30 grams, 12 grams of dried rhizome of rehmannia of 12 grams of Rhizoma Picrorhizae of 18 grams of bletilla striatas of Root-bark of Chinese Wolfberry
18 grams of the wind-weeds
Hold up and win No. II
10 grams, 18 grams of shizandra berry of 25 grams of Poria cocos of Radix Codonopsis 20 Keshan medicine
12 grams of 12 grams of tiger battles of 10 grams of Yunnan Caulis Spatholobis of 20 grams of Radix Angelicae Sinensis of cultivated land
20 grams of 12 grams of Radixs Astragali of the bighead atractylodes rhizome
When preparation:
First gekko pulverization and donkey-hide gelatin are decocted to stir-fry, more each taste medicine is cleaned, dries, pulverized, pulverization, sieve into pulvis after No. 6, be packaged into bag, hold up and win No. I, take half an hour after meal, produce to hold up and win when II, equally each medicine selected, cleaned, pulverizing, pulverization, cross and sieve into pulvis, packaging, one-tenth bag for No. 6, hold up win No. II, take half an hour ante cibum, when treatment, combines compatibility, takes with Western medicine.
The Western medicine combination of combined chemotherapy has:
Streptomycin sulphate injection liquid: consumption is for once a day, 0.78 gram of intramuscular injection;
Isoniazid tablets: consumption is every day three times, each serving 0.4 gram;
Rifampin: consumption is every day three times, each serving 0.4 gram;
Pyrazinamide capsule: consumption is every twice-daily, takes 2 grams after the meal.
Mentioned coupling group above and be traditional Chinese and western medicine drug combination, chemotherapy group is also chemotherapy medication.
Two groups are carried out the comparison of comprehensive function changing conditions below, and the treatment of two groups of cases is after 6 months, about being compared as follows of comprehensive function changing conditions, and normal 115 examples of coupling group, abnormal example 5 examples, normal 91 examples of chemotherapy group, anomalies: analysis of 29 cases, concrete data are in table 1:
Table 1 liang group is about the comparison (example) of changes of liver function situation
| Group | Number of cases | Normally | Lead normal | Natural rate of interest (%) |
| Coupling group | 120 | 115 | 5 | 95.8 |
| Chemotherapy group | 120 | 91 | 29 | 75.8 |
| Add up to | 240 | 206 | 34 | 85.8 |
Result demonstration, coupling group natural rate of interest is 95.8%, chemotherapy group is 75.8%.
Learn and process more by statistics for two groups, difference has statistical significance (P > 0.05).Show two groups larger about changes of liver function situation difference, illustrate that the liver protective effect of coupling group is better than chemotherapy group, prompting Chinese medicine hold up win series aspect liver function protecting, have unique effect.
Two groups of two groups of case treatments of comparison about curative ratio are after 6 months, and as follows about curative ratio situation, coupling group is cured 116 examples, and 3 examples that take a turn for the better, without changing 1 example; Chemotherapy group is cured 105 examples, and 13 examples that take a turn for the better, without changing 2 examples.Concrete data are in table 2.
Result demonstration, coupling group curative ratio is 96.7, chemotherapy group is 87.5%.Learn and process more by statistics for two groups, difference has statistical significance (P > 0.05).Show two groups larger about curative ratio difference, illustrate that coupling group treats phthisical whole structure and be better than chemotherapy group, Chinese medicine is held up and is won coupled in series chemotherapy and having enhancement aspect the phthisical overall curative ratio for the treatment of.
The comparison (example) of table 2 liang group result for the treatment of
| Group | Number of cases | Cure | Take a turn for the better | Unchanged | Curative ratio (%) |
| Coupling group | 120 | 116 | 3 | 1 | 96.7 |
| Chemotherapy group | 120 | 105 | 13 | 2 | 87.5 |
| Add up to | 240 | 221 | 16 | 3 | 92.1 |
Note: P:=0.025
The comparison of two groups of untoward reactions, two groups in therapeutic process untoward reaction that a situation arises is as follows, in chemotherapy group, have 5 examples to occur untoward reaction, that symptom has is nauseating, vomit, have a stomach upset etc., does not interrupt drug withdrawal through anti symptom treatment.And coupling group only has 2 examples to occur.
Clinical control by two group of 240 routine tuberculosis cases is observed, the negative conversion rate of the Sputum smear of coupling group is 84.2%, chemotherapy group is 82.8%, two group and learns and process, difference not statistically significant (P > 0.05) more by statistics.Two groups of comparisons about x-ray focus absorbing state, result demonstration, coupling group specific absorption is 98.3%, chemotherapy group is 97.9%.Learn and process, difference not statistically significant (P > 0.05) more by statistics for two groups.Show two groups little about x-ray focus absorbing state difference.Two groups of demonstrations of the comparative results about changes of liver function situation, coupling group natural rate of interest is 95.8%, chemotherapy group is 75.8%.Learn and process more by statistics for two groups, difference has statistical significance (P < 0.05).Show two groups larger about changes of liver function situation difference, illustrate that the liver protective effect of coupling group is better than chemotherapy group, prompting Chinese medicine hold up win series aspect liver function protecting, have unique effect.Two groups of comparisons about curative ratio, result demonstration, coupling group curative ratio is 96.7%, chemotherapy group is 87.5%.Learn and process more by statistics for two groups, difference has statistical significance (P < 0.05).Show two groups larger about curative ratio difference, illustrate that coupling group treats phthisical whole structure and be better than chemotherapy group, prompting Chinese medicine is held up and is won coupled in series chemotherapy and having enhancement aspect the phthisical overall curative ratio for the treatment of.Two groups of comparisons about side reaction, two groups in therapeutic process side reaction that a situation arises is as follows, in chemotherapy group, have 5 examples to occur side reaction, symptom has: feel sick, vomiting, has a stomach upset etc., does not interrupt drug withdrawal through anti symptom treatment.And coupling group only has 2 examples to occur.
Model case
1, patient, man, 46 years old, Jilin Shuangliao people from county, the diagnosis and treatment of 2004 Nian Laiwo institutes.Patient before 2 days without any inducement occur cough, hectic fever, night sweat, weak, receive poorly, treat aggravation and the diagnosis and treatment of Lai Wo institute with intrapulmonary infection at local hospital.Through x-ray rabat and plate coating checking prompting lung infiltrative pulmonary tuberculosis, tcm diagnosis: tuberculosis (YIN-deficiency type of the lung and kidney).Past medical history: hectic clinical cure once before 8 years.Now hold up and win series traditional Chinese cooperation Western medicine chemotherapy 6 months, symptom is obviously improved, and after 2 months, phlegm the moon turns, and finishes x-ray rabat check disease kitchen range obviously absorb through the course for the treatment of, follows up a case by regular visits to recurrence that so far there are no 1 year.
2, Jin Fu, man, 42 years old, people from Lishu County.The diagnosis and treatment of 1999 Nian Laiwo institutes, patient goes out low-heat without obvious inducement in one week, cough, few phlegm, treat with " intrapulmonary infection " at local hospital, aggravation after one week, and the diagnosis and treatment of Lai Wo institute, through X rabat and be coated with biopsy and look into the left lung of prompting and infiltrate pulmonary tuberculosis, tcm diagnosis tuberculosis (deficiency of lung-YIN type), past medical history: hectic clinical cure once before 8 years, now hold up win series traditional Chinese two to control Western medicine chemotherapy after six months, symptom is obviously improved, and after 2 months, phlegm limit turns, and finishes x-ray rabat reexamine focus obviously absorb through the course for the treatment of, follow up a case by regular visits to recurrence that so far there are no 1 year.
3, Li Jinlan, female, 62 years old, people from Changtu County.The diagnosis and treatment of calendar year 2001 Lai Wo institute, patient was interrupted cough without obvious inducement before two months, and a little whitish yellow sputum is weak, occasionally breathes hard, and activity postemphasis, without generating heat, without night sweat.Treat with " upper respiratory infection " at local hospital, aggravation after three days, clap the doubtful pulmonary tuberculosis of rabat by local hospital, therefore be system Lai Wo institute, check mutually pulmonary tuberculosis on the two lungs of prompting, phlegm smear through necessity, tcm diagnosis lung cancer (type of deficiency of both QI and YIN), previously, without pulmonary tuberculosis history, now hold up and win series traditional Chinese cooperation Western medicine chemotherapy six months, symptom is obviously improved (the same) below.
4, Zou Jinxia, female, 51 years old, Shuangliao people from county.The diagnosis and treatment of 2002 Nian Laiwo institutes, patient had a fever without obvious inducement before three months, 37.5 DEG C, yellow phlegm, breathes hard, activity postemphasis, without night sweat, dry mouth and throat, in local chest film inspection pulmonary tuberculosis, previously hectic once before 20 years, thus the diagnosis and treatment of Su Laiwo institute, through pressing mutually inspection, diagnosis, the upper infiltrative pulmonary tuberculosis of two lungs, the district of overdrawing on right lung, smear, tcm diagnosis: lung cancer (type of deficiency of both QI and YIN), remaining the same.
5 Yang Zi rivers, man, 35 years old, Gongzhuling City people, before patient's two weeks, there is fever, cough, white phlegm, sauce sweat, dry mouth and throat without obvious inducement, the medication voluntarily (concrete medication not quite clear) of being in, have no Lai Wo institute, diagnose left pulmonary tuberculosis lung upper through film making, smear, phlegm is many, tcm diagnosis tuberculosis (type of hyperactivity of fire caused by deficiency of YIN), remaining the same.
6, Liang Zhongwu, man, 68 years old, Guo Jia people from shop, before patient's fortnight, without obvious inducement, cough, thin, white sweat night sweat, low bath, insomnia, diet, sleep is all not good enough, through local hospital inspection, doubtful " pulmonary tuberculosis " is for asking system diagnostics and treatment, and Lai Wo institute, through film making CT examination, smear, the two lung upper, middle and lower tuberculosis of diagnosis, phlegm bacterium, tcm diagnosis: tuberculosis (lung yin sun deficiency), remaining the same.
7, Wu Gang, man, 36 years old, people from Siping City, before patient's one star, dry cough, few phlegm, weak, activity postemphasis, pulmonary tuberculosis on doubtful right lung, phlegm bacterium, tcm diagnosis: tuberculosis (deficiency of lung-YIN type) previously: health.
8, high refined half, female, 49 years old, elm people from county, before patient half a year, without obvious inducement, fever 37.3-38 DEG C, night sweat, feverish sensation in the palms and soles, thin, dry mouth and throat.
Diagnosis: the upper tuberculosis of two lungs (being above cavity) tcm diagnosis, YIN-deficiency type of the lung and kidney.
9, Wu Chunfang, female, 38 years old, two mausoleums Ziren, patient is before one week, occur cough, weak, breathe hard, activity postemphasis, sleep not good enough.Diagnosis: the upper pulmonary tuberculosis of left lung, phlegm is coated with, tcm diagnosis: lung cancer (type of deficiency of both QI and YIN).
10, Liu Shulai, female, 72 years old, people from Changtu County, occur before patient's two weeks cough, breathe heavily, yellow phlegm, without fever, even night sweat, breathe hard, activity postemphasis, the past pulmonary tuberculosis medical history 30 years.
Diagnosis: two lung upper, middle and lower tuberculosis is coated with, tcm diagnosis: tuberculosis (type of deficiency of both QI and YIN).
11, Wang faithful and upright person, man, 49 years old, lonely home people from town, there is low fever, night sweat, become thin in patient, feverish sensation in the palms and soles, dry mouth and throat, previously healthy before 10 days.
Diagnosis: tuberculosis on two lungs, phlegm is many, tcm diagnosis: lung cancer (type of hyperactivity of fire caused by deficiency of YIN).
Tuberculosis is the chronic infectious disease of serious harm human health.China's tuberculosis epidemic situation is more serious, is one of the high burden of 22, whole world tuberculosis country, and lunger is only second to India, occupies second.The sternness of tuberculosis epidemic situation directly affects the healthy of the people and national economy situation.Grasping and controlling epidemic situation lungy is the major issue that is related to national economy, is the important evidence of working out targeted prevention and control measure.
Claims (2)
1. a Chinese medicine is held up and is won the phthisical medicine of combination chemotherapy, it is made up of following traditional Chinese medicines, according to each medicine effect, effect, according to monarch, minister, make, assistant relation is divided into holding up and wins No. I and hold up and win No. II, it holds up the Chinese medicine of winning I compatibility to have gekko, donkey-hide gelatin, the tuber of stemona, the root of straight ladybell, the tuber of dwarf lilyturf, Spica Prunellae, radix scrophulariae, the bulb of fritillary, Root-bark of Chinese Wolfberry, the bletilla striata, Picrorhiza scrophulariiflora, the dried rhizome of rehmannia, the wind-weed; Hold up that the Chinese medicine of winning II compatibility has that Radix Codonopsis, Chinese yam, Poria cocos, shizandra berry, cultivated land, Radix Angelicae Sinensis, chicken blood are risen, brave battle, the bighead atractylodes rhizome, the Radix Astragali; Participating in Western medicine and the using method of combined chemotherapy is: Streptomycin sulphate injection liquid: consumption is for once a day, 0.73 gram～0.9 gram of intramuscular injection; Isoniazid tablets: consumption is every day three times, each 0.2～0.5 gram; Rifampin: consumption is every day three times, each 0.3～0.5 gram; Pyrazinamide capsule: consumption is every twice-daily, takes each 1～3 gram after the meal; It is characterized in that:
(1) the described weight ratio of winning each taste medicine in No. I its compatibility of holding up is:
8～17 grams of gekkos, 15～20 grams, donkey-hide gelatin, 15～25 grams of the tubers of stemona, 15～25 grams of the root of straight ladybell, 15～25 grams of the tubers of dwarf lilyturf, 10～15 grams of Spica Prunellaes, 15～20 grams of radix scrophulariaes, 10～15 grams of the bulbs of fritillary, 15～20 grams of Root-bark of Chinese Wolfberry, 10～15 grams of the bletilla striatas, 10～15 grams of Rhizoma Picrorhizae, 20～40 grams, the dried rhizome of rehmannia, 15～20 grams of the wind-weeds;
(2) the described weight ratio of winning each taste medicine in No. II its compatibility of holding up is:
15～25 grams of Radix Codonopsis, 15～30 grams of Chinese yams, 15～20 grams, Poria cocos, 10～12 grams, shizandra berry, 10～25 grams, cultivated land, 8～15 grams of Radix Angelicae Sinensis, 10～15 grams of Yunnan Caulis Spatholobis, 10～15 grams of tiger battles, 10～15 grams of the bighead atractylodes rhizomes, 15～25 grams of the Radixs Astragali.
2. a kind of Chinese medicine according to claim 1 is held up and is won the phthisical medicine of combination chemotherapy, it is characterized in that:
(1) hold up and win the best dosage of No. I and be:
10 grams of gekkos, 18 grams, donkey-hide gelatin, 20 grams of the tubers of stemona, 18 grams of the root of straight ladybell, 20 grams of the tubers of dwarf lilyturf, 12 grams of Spica Prunellaes, 18 grams of radix scrophulariaes, 12 grams of the bulbs of fritillary, 18 grams of Root-bark of Chinese Wolfberry, 12 grams of the bletilla striatas, 12 grams of Rhizoma Picrorhizae, 30 grams, the dried rhizome of rehmannia, 18 grams of the wind-weeds;
(2) hold up and win the best dosage of No. II and be:
20 grams of Radix Codonopsis, 25 grams of Chinese yams, 18 grams, Poria cocos, 10 grams, shizandra berry, 20 grams, cultivated land, 10 grams of Radix Angelicae Sinensis, 12 grams of Yunnan Caulis Spatholobis, 12 grams of tiger battles, 12 grams of the bighead atractylodes rhizomes, 20 grams of the Radixs Astragali.
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| CN103656422B (en) * | 2013-11-20 | 2016-04-20 | 田博 | A kind of Chinese medicine composition for the treatment of asthmatic bronchitis |
| CN103656406B (en) * | 2013-11-21 | 2015-08-19 | 蒋学 | One treats phthisical medicine and preparation method thereof |
| CN105055860A (en) * | 2015-08-24 | 2015-11-18 | 臧兰恕 | Traditional Chinese medicine composition for treating yin deficiency fire excess type phthisis |
| CN111407865A (en) * | 2020-04-13 | 2020-07-14 | 贺启飞 | Pulmonary perforation combined traditional Chinese medicine formula for treating pulmonary tuberculosis |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1354014A (en) * | 2001-11-29 | 2002-06-19 | 廖干甫 | Gongbu ointment |
| CN1772256A (en) * | 2005-09-27 | 2006-05-17 | 韩云超 | Tuberculosis treating Chinese medicine |
| CN101249241A (en) * | 2008-03-10 | 2008-08-27 | 许文成 | Medicament for radically treating phthisis and method of preparing the same |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1354014A (en) * | 2001-11-29 | 2002-06-19 | 廖干甫 | Gongbu ointment |
| CN1772256A (en) * | 2005-09-27 | 2006-05-17 | 韩云超 | Tuberculosis treating Chinese medicine |
| CN101249241A (en) * | 2008-03-10 | 2008-08-27 | 许文成 | Medicament for radically treating phthisis and method of preparing the same |
Non-Patent Citations (2)
| Title |
|---|
| 自拟中药扶羸联合化疗治疗肺结核的疗效观察;辛焰;《首席医学网》;20080214;http://journal.9med.net/qikan/article.php?id=324244 * |
| 辛焰.自拟中药扶羸联合化疗治疗肺结核的疗效观察.《首席医学网》.2008,http://journal.9med.net/qikan/article.php?id=324244. |
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