CN102755477A - Externally-used plaster for treating onychomycosis - Google Patents
Externally-used plaster for treating onychomycosis Download PDFInfo
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- CN102755477A CN102755477A CN2011101157247A CN201110115724A CN102755477A CN 102755477 A CN102755477 A CN 102755477A CN 2011101157247 A CN2011101157247 A CN 2011101157247A CN 201110115724 A CN201110115724 A CN 201110115724A CN 102755477 A CN102755477 A CN 102755477A
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- parts
- acetic acid
- glacial acetic
- semen
- fengxian
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- 208000010195 Onychomycosis Diseases 0.000 title claims abstract description 24
- 201000005882 tinea unguium Diseases 0.000 title claims abstract description 24
- 239000011505 plaster Substances 0.000 title abstract 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims abstract description 48
- 210000000582 semen Anatomy 0.000 claims abstract description 34
- 229960000583 acetic acid Drugs 0.000 claims abstract description 24
- 239000012362 glacial acetic acid Substances 0.000 claims abstract description 24
- 229910052957 realgar Inorganic materials 0.000 claims abstract description 12
- 229940099259 vaseline Drugs 0.000 claims abstract description 12
- 239000002674 ointment Substances 0.000 claims description 15
- 241000255791 Bombyx Species 0.000 claims description 11
- 241000533849 Gleditsia Species 0.000 claims description 11
- QQILFGKZUJYXGS-UHFFFAOYSA-N Indigo dye Chemical compound C1=CC=C2C(=O)C(C3=C(C4=CC=CC=C4N3)O)=NC2=C1 QQILFGKZUJYXGS-UHFFFAOYSA-N 0.000 claims description 11
- 239000000203 mixture Substances 0.000 claims description 6
- 239000012467 final product Substances 0.000 claims description 5
- 238000000227 grinding Methods 0.000 claims description 5
- 238000007654 immersion Methods 0.000 claims description 5
- 239000000463 material Substances 0.000 claims description 5
- 238000012856 packing Methods 0.000 claims description 5
- 238000003756 stirring Methods 0.000 claims description 5
- 239000003814 drug Substances 0.000 claims description 4
- 239000006260 foam Substances 0.000 claims description 2
- 238000004519 manufacturing process Methods 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 21
- 239000002994 raw material Substances 0.000 abstract description 4
- 241000255789 Bombyx mori Species 0.000 abstract 1
- 244000018716 Impatiens biflora Species 0.000 abstract 1
- 235000015912 Impatiens biflora Nutrition 0.000 abstract 1
- 235000000177 Indigofera tinctoria Nutrition 0.000 abstract 1
- 241000218681 Pseudolarix Species 0.000 abstract 1
- 240000000528 Ricinus communis Species 0.000 abstract 1
- 235000004443 Ricinus communis Nutrition 0.000 abstract 1
- 241000270295 Serpentes Species 0.000 abstract 1
- 240000001949 Taraxacum officinale Species 0.000 abstract 1
- 235000005187 Taraxacum officinale ssp. officinale Nutrition 0.000 abstract 1
- 229940037003 alum Drugs 0.000 abstract 1
- 229940097275 indigo Drugs 0.000 abstract 1
- COHYTHOBJLSHDF-UHFFFAOYSA-N indigo powder Natural products N1C2=CC=CC=C2C(=O)C1=C1C(=O)C2=CC=CC=C2N1 COHYTHOBJLSHDF-UHFFFAOYSA-N 0.000 abstract 1
- 239000001397 quillaja saponaria molina bark Substances 0.000 abstract 1
- 229930182490 saponin Natural products 0.000 abstract 1
- 150000007949 saponins Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 231100000614 poison Toxicity 0.000 description 4
- 239000002574 poison Substances 0.000 description 3
- 238000002560 therapeutic procedure Methods 0.000 description 3
- 238000005303 weighing Methods 0.000 description 3
- 206010007247 Carbuncle Diseases 0.000 description 2
- 206010012504 Dermatophytosis Diseases 0.000 description 2
- 206010017533 Fungal infection Diseases 0.000 description 2
- 241001460074 Microsporum distortum Species 0.000 description 2
- 208000031888 Mycoses Diseases 0.000 description 2
- 208000002474 Tinea Diseases 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 230000035876 healing Effects 0.000 description 2
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 230000000590 parasiticidal effect Effects 0.000 description 2
- 238000007790 scraping Methods 0.000 description 2
- 230000008961 swelling Effects 0.000 description 2
- 235000001674 Agaricus brunnescens Nutrition 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 208000003322 Coinfection Diseases 0.000 description 1
- 208000035473 Communicable disease Diseases 0.000 description 1
- 206010010904 Convulsion Diseases 0.000 description 1
- IIUZTXTZRGLYTI-UHFFFAOYSA-N Dihydrogriseofulvin Natural products COC1CC(=O)CC(C)C11C(=O)C(C(OC)=CC(OC)=C2Cl)=C2O1 IIUZTXTZRGLYTI-UHFFFAOYSA-N 0.000 description 1
- UXWOXTQWVMFRSE-UHFFFAOYSA-N Griseoviridin Natural products O=C1OC(C)CC=C(C(NCC=CC=CC(O)CC(O)C2)=O)SCC1NC(=O)C1=COC2=N1 UXWOXTQWVMFRSE-UHFFFAOYSA-N 0.000 description 1
- 208000032843 Hemorrhage Diseases 0.000 description 1
- 241000475481 Nebula Species 0.000 description 1
- DDUHZTYCFQRHIY-UHFFFAOYSA-N Negwer: 6874 Natural products COC1=CC(=O)CC(C)C11C(=O)C(C(OC)=CC(OC)=C2Cl)=C2O1 DDUHZTYCFQRHIY-UHFFFAOYSA-N 0.000 description 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 230000000146 antalgic effect Effects 0.000 description 1
- 230000000843 anti-fungal effect Effects 0.000 description 1
- 229940121375 antifungal agent Drugs 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 229940126678 chinese medicines Drugs 0.000 description 1
- 230000036461 convulsion Effects 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 244000053095 fungal pathogen Species 0.000 description 1
- DDUHZTYCFQRHIY-RBHXEPJQSA-N griseofulvin Chemical compound COC1=CC(=O)C[C@@H](C)[C@@]11C(=O)C(C(OC)=CC(OC)=C2Cl)=C2O1 DDUHZTYCFQRHIY-RBHXEPJQSA-N 0.000 description 1
- 229960002867 griseofulvin Drugs 0.000 description 1
- 238000007802 hot water maceration Methods 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000000749 insecticidal effect Effects 0.000 description 1
- 239000002917 insecticide Substances 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 230000002147 killing effect Effects 0.000 description 1
- 230000001050 lubricating effect Effects 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000035943 smell Effects 0.000 description 1
- 238000010025 steaming Methods 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention discloses an externally-used plaster for treating onychomycosis. The externally-used plaster for treating the onychomycosis is characterized by comprising the following raw materials in part by weight: 10-12 parts of natural indigo, 10-12 parts of dried alum, 15-18 parts of realgar, 10-12 parts of dandelion, 10-12 parts of cortex lycii radicis, 18-20 parts of pseudolarix, 15-18 parts of snake slough, 10-12 parts of stiff silkworm, 10-12 parts of rhizoma arisaematis, 18-20 parts of saponin, 10-12 parts of unprocessed radix aconiti, 15-18 parts of castor bean, 15-18 parts of wind fairy, 18-20 parts of radix sophorae flavescentis, 30-50 parts of vaseline, 15-18 parts of semen momordicae, 15-18 parts of impatiens balsamina and 400-700 parts of glacial acetic acid. The externally-used plaster for treating the onychomycosis is good in therapeutic effect, short in course of treatment, small in side effect and convenient to use.
Description
Technical field
The present invention relates to a kind of external Chinese medicine that is used to treat tinea unguium, belong to the field of Chinese medicines.
Background technology
Tinea unguium is that a kind of people of occurring in refers to the infectious disease on (toe) first, medically is called tinea unguium, and it is caused that by fungal infection the traditional Chinese medical science is referred to as " tinea unguium ", " tinea unguium ", " tinea unguium " etc.The pathogenic fungi that can cause tinea unguium has many kinds; Up-to-date nosetiology survey result shows: Chinese tinea unguium mainly is to be caused by dermatophytosis, yeast and three kinds of fungal infection of mycete; And have a certain proportion of mixed infection, tinea unguium is a kind of of the most obstinate refractory in various dermatophytosis.The traditional therapy of tinea unguium be before medication with the crisp sick first of pocket knife scraping, or, be coated with 5% iodine tincture or 10-30% glacial acetic acid solution then with sick first skiving.This method will adhere to just taking effect in 1 year at least, and a lot of patients are often because the color of iodine, the abnormal smells from the patient of glacial acetic acid and the course of treatment oversize and TD.Treat serious tinea unguium, also will take the griseofulvin some months orally, this Therapeutic Method tends to recur tinea unguium again.
Summary of the invention
The objective of the invention is to want to provide a kind of external-applied ointment of new treatment tinea unguium, this ointment good effect, healing speed is fast.
For realizing that the technical scheme that above-mentioned purpose of the present invention adopts is: a kind of externally applied ointment of treating tinea unguium is characterized in that being processed by following materials of weight proportions: Indigo Naturalis 10-12, dried Alumen 10-12, Realgar 15-18, Herba Taraxaci 10-12, Cortex Lycii 10-12, Cortex Pseudolaricis 18-20, Periostracum Serpentis 15-18, Bombyx Batryticatus 10-12, Rhizoma Arisaematis 10-12, Fructus Gleditsia 18-20, Radix Aconiti Kusnezoffii 10-12, Semen Ricini 15-18, the sub-15-18 of FENGXIAN, Radix Sophorae Flavescentis 18-20, vaseline 30-50, Semen Momordicae 15-18, Semen Impatientis 15-18, glacial acetic acid 400-700.
Manufacture method: Cortex Lycii, Rhizoma Arisaematis, Fructus Gleditsia, Cortex Pseudolaricis, Semen Ricini, FENGXIAN, Semen Momordicae are pressed into broken foam, put into glacial acetic acid, airtight immersion 15 days is filtered, and gets glacial acetic acid filtrating; With Indigo Naturalis, dried Alumen, Realgar, Herba Taraxaci, Periostracum Serpentis, Bombyx Batryticatus, Radix Aconiti Kusnezoffii, FENGXIAN, Radix Sophorae Flavescentis, Semen Impatientis grinding Cheng Mo, cross 200 mesh sieves, behind the mix homogeneously, stirring with vaseline and glacial acetic acid filtrating is the ointment shape, and packing gets final product.
Therapeutic Method: before applying ointment, first (toe) first that ash is referred to is used the hot water maceration, the sick first of reuse blade scraping in layer gently; Hemorrhage with not; Painless is degree, then ointment is coated on the disease first equably, and application area will exceed the disease first; Every day early, respectively carry out once evening, 7 days is a course of treatment.
The present invention is to the further developing of secret prescription handed down in the family from generation to generation, the scientific formulation that is adopted, and drug effect is high, and selected each medicine can synergism, reaches and kills the purpose that ash refers to bacterium fully.The effect that has heat-clearing and toxic substances removing like the Indigo Naturalis that is adopted; Dried Alumen has heat clearing away, the effect of dampness; Realgar has the parasiticidal effect of detoxifcation; Herba Taraxaci has the effect of eliminating carbuncle eliminating stagnation; Cortex Lycii has removing heat from blood and removes the effect of steaming; Cortex Pseudolaricis has the effect of Anti-Puritic and insecticidal; Periostracum Serpentis has detoxifcation, the effect of nebula removing; Bombyx Batryticatus has the effect of expelling wind to relieve convulsion; Rhizoma Arisaematis has the effect of mass dissipating and swelling eliminating; Fructus Gleditsia has the detumescence poison holding, evacuation of pus, parasiticidal effect; Radix Aconiti Kusnezoffii has expelling wind and removing dampness, the effect of antalgic; Semen Ricini has the effect of detumescence and drawing out poison; FENGXIAN has the effect of controlling carbuncle sore tumefacting virus; Radix Sophorae Flavescentis has heat clearing and damp drying; The effect of wind dispelling insecticide; Vaseline has the effect of preserving moisture, lubricating; Semen Momordicae has dispersing swelling and dissipating binds, the effect of the poison of dispelling; Semen Impatientis has the removing blood stasis softening the hard mass, silt repercussive effect relieves internal heat, looses; Glacial acetic acid has antifungal, anticorrosion, sterilization and corrosive effect.The invention has the beneficial effects as follows that good effect, short treating period, side effect are little, easy to use.This product has good killing action to the mushroom that causes tinea unguium, and is safe and reliable, convenient and healthy.Show that through the use to 47 patients total effective rate reaches 96% over 5 years, the lighter uses to fully recover 3-4 the course of treatment; Weight person 6-8 can fully recover a course of treatment; Follow-up investigation through to user shows, 43 no longer recurrences among the healing person of institute, and the recurrence patient has two.
The specific embodiment
Example below in conjunction with practical implementation is done further detailed description to the present invention.
Embodiment 1: take by weighing down routine raw material by weight: a kind of externally applied ointment of treating tinea unguium is characterized in that being processed by following materials of weight proportions: Indigo Naturalis 10g, dried Alumen 10g, Realgar 15g, Herba Taraxaci 10g, Cortex Lycii 10g, Cortex Pseudolaricis 18g, Periostracum Serpentis 15g, Bombyx Batryticatus 10g, Rhizoma Arisaematis 10g, Fructus Gleditsia 18g, Radix Aconiti Kusnezoffii 10g, Semen Ricini 15g, the sub-15g of FENGXIAN, Radix Sophorae Flavescentis 18g, vaseline 30g, Semen Momordicae 15g, Semen Impatientis 15g, glacial acetic acid 400g.Cortex Lycii, Rhizoma Arisaematis, Fructus Gleditsia, Cortex Pseudolaricis, Semen Ricini, FENGXIAN, Semen Momordicae are put into glacial acetic acid, and airtight immersion 15 days is filtered, and gets glacial acetic acid filtrating; With Indigo Naturalis, dried Alumen, Realgar, Herba Taraxaci, Periostracum Serpentis, Bombyx Batryticatus, Radix Aconiti Kusnezoffii, FENGXIAN, Radix Sophorae Flavescentis, Semen Impatientis grinding Cheng Mo, cross 200 mesh sieves, behind the mix homogeneously, stirring with vaseline and glacial acetic acid filtrating is the ointment shape, and packing gets final product.
Embodiment 2: take by weighing down routine raw material by weight: a kind of externally applied ointment of treating tinea unguium is characterized in that being processed by following materials of weight proportions: Indigo Naturalis 12g, dried Alumen 12g, Realgar 18g, Herba Taraxaci 12g, Cortex Lycii 12g, Cortex Pseudolaricis 20g, Periostracum Serpentis 18g, Bombyx Batryticatus 12g, Rhizoma Arisaematis 12g, Fructus Gleditsia 20g, Radix Aconiti Kusnezoffii 12g, Semen Ricini 18g, the sub-18g of FENGXIAN, Radix Sophorae Flavescentis 20g, vaseline 50g, Semen Momordicae 18g, Semen Impatientis 18g, glacial acetic acid 700g.Cortex Lycii, Rhizoma Arisaematis, Fructus Gleditsia, Cortex Pseudolaricis, Semen Ricini, FENGXIAN, Semen Momordicae are put into glacial acetic acid, and airtight immersion 15 days is filtered, and gets glacial acetic acid filtrating; With Indigo Naturalis, dried Alumen, Realgar, Herba Taraxaci, Periostracum Serpentis, Bombyx Batryticatus, Radix Aconiti Kusnezoffii, FENGXIAN, Radix Sophorae Flavescentis, Semen Impatientis grinding Cheng Mo, cross 200 mesh sieves, behind the mix homogeneously, stirring with vaseline and glacial acetic acid filtrating is the ointment shape, and packing gets final product.
Embodiment 3: take by weighing down routine raw material by weight: a kind of externally applied ointment of treating tinea unguium is characterized in that being processed by following materials of weight proportions: Indigo Naturalis 11g, dried Alumen 11g, Realgar 16g, Herba Taraxaci 11g, Cortex Lycii 11g, Cortex Pseudolaricis 19g, Periostracum Serpentis 16g, Bombyx Batryticatus 11g, Rhizoma Arisaematis 11g, Fructus Gleditsia 19g, Radix Aconiti Kusnezoffii 11g, Semen Ricini 16g, the sub-16g of FENGXIAN, Radix Sophorae Flavescentis 19g, vaseline 40g, Semen Momordicae 16g, Semen Impatientis 16g, glacial acetic acid 500g.Cortex Lycii, Rhizoma Arisaematis, Fructus Gleditsia, Cortex Pseudolaricis, Semen Ricini, FENGXIAN, Semen Momordicae are put into glacial acetic acid, and airtight immersion 15 days is filtered, and gets glacial acetic acid filtrating; With Indigo Naturalis, dried Alumen, Realgar, Herba Taraxaci, Periostracum Serpentis, Bombyx Batryticatus, Radix Aconiti Kusnezoffii, FENGXIAN, Radix Sophorae Flavescentis, Semen Impatientis grinding Cheng Mo, cross 200 mesh sieves, behind the mix homogeneously, stirring with vaseline and glacial acetic acid filtrating is the ointment shape, and packing gets final product.
Claims (2)
1. externally applied ointment of treating tinea unguium is characterized in that being processed by following materials of weight proportions: Indigo Naturalis 10-12, dried Alumen 10-12, Realgar 15-18, Herba Taraxaci 10-12, Cortex Lycii 10-12, Cortex Pseudolaricis 18-20, Periostracum Serpentis 15-18, Bombyx Batryticatus 10-12, Rhizoma Arisaematis 10-12, Fructus Gleditsia 18-20, Radix Aconiti Kusnezoffii 10-12, Semen Ricini 15-18, the sub-15-18 of FENGXIAN, Radix Sophorae Flavescentis 18-20, vaseline 30-50, Semen Momordicae 15-18, Semen Impatientis 15-18, glacial acetic acid 400-700.
2. a method of making said medicine is characterized in that Cortex Lycii, Rhizoma Arisaematis, Fructus Gleditsia, Cortex Pseudolaricis, Semen Ricini, FENGXIAN, Semen Momordicae are pressed into broken foam, puts into glacial acetic acid, and airtight immersion 15 days is filtered, and gets glacial acetic acid filtrating; With Indigo Naturalis, dried Alumen, Realgar, Herba Taraxaci, Periostracum Serpentis, Bombyx Batryticatus, Radix Aconiti Kusnezoffii, FENGXIAN, Radix Sophorae Flavescentis, Semen Impatientis grinding Cheng Mo, cross 200 mesh sieves, behind the mix homogeneously, stirring with vaseline and glacial acetic acid filtrating is the ointment shape, and packing gets final product.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN2011101157247A CN102755477A (en) | 2011-04-24 | 2011-04-24 | Externally-used plaster for treating onychomycosis |
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CN2011101157247A CN102755477A (en) | 2011-04-24 | 2011-04-24 | Externally-used plaster for treating onychomycosis |
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CN2011101157247A Pending CN102755477A (en) | 2011-04-24 | 2011-04-24 | Externally-used plaster for treating onychomycosis |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105878515A (en) * | 2016-05-27 | 2016-08-24 | 廖鲜芳 | Matching agent for treating onychomycosis |
CN106389761A (en) * | 2016-05-27 | 2017-02-15 | 袁显兰 | Traditional Chinese medicinal composition for treating onychomycosis and preparation method of traditional Chinese medicinal composition |
-
2011
- 2011-04-24 CN CN2011101157247A patent/CN102755477A/en active Pending
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105878515A (en) * | 2016-05-27 | 2016-08-24 | 廖鲜芳 | Matching agent for treating onychomycosis |
CN106389761A (en) * | 2016-05-27 | 2017-02-15 | 袁显兰 | Traditional Chinese medicinal composition for treating onychomycosis and preparation method of traditional Chinese medicinal composition |
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Application publication date: 20121031 |