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CN102716276B - Medicine for oral use for treating diabetes - Google Patents

Medicine for oral use for treating diabetes Download PDF

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Publication number
CN102716276B
CN102716276B CN201110166608.8A CN201110166608A CN102716276B CN 102716276 B CN102716276 B CN 102716276B CN 201110166608 A CN201110166608 A CN 201110166608A CN 102716276 B CN102716276 B CN 102716276B
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China
Prior art keywords
medicine
weight parts
diabetes
parts
treating diabetes
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Expired - Fee Related
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CN201110166608.8A
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Chinese (zh)
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CN102716276A (en
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王长锋
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  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The invention, relating to the field of traditional Chinese medicine, discloses a medicine for oral use for treating diabetes, solving the problems of slow effect of treatment, harm to mind and body caused by long-term use of medicines, etc. existing in the prior art. The medicine comprises the following ingredients: 15-20 weight parts of Radix Rehmanniae, 15-20 weight parts of Fructus Lycii, 10-15 weight parts of Astragalus complanatus, 15-20 weight parts of Fructus corni, and 5-10 weight parts of Irisensata Thunb. The medicine of the invention based on adopting traditional therapies for reducing blood sugar has effects of supplementing Qi and nourishing Yin, clearing heat and engendering fluid, and reducing blood sugar on treating diabetes, thus blood sugar and urine sugar are effectively controlled.

Description

The oral medicine for the treatment of diabetes
Technical field:
The present invention relates to the field of Chinese medicines, be specially a kind of oral medicine for the treatment of diabetes.
Background technology:
Diabetes are a kind of common frequently-occurring diseases, are the third-largest common death factors that is only second to heart disease and cancer.In decades, countries in the world are carried out long-term and unremitting research and development one after another.
Doctor trained in Western medicine is mainly that application insulin and oral sulfonylureas drugs for diabetes are treated clinically, and can obtain and temporarily fall hypoglycemic curative effect.
At present, the prescription for the treatment of diabetes is a lot, but due to diabetes pathology, etiological study are not also had to substantial breakthrough so far, the conceptual phase that treatment diabetes still increase the stage and prevent comprehensive complication in controlling blood glucose, glucose in urine.In addition, needs of patients long-term prescription, responds well to treatment slow, and can bring side effect to internal organs such as kidney, liver, the heart, spleen, stomaches.
Facts have proved, motherland's medicine and pharmacology are accumulating rich experience aspect treatment diabetes, and the traditional Chinese medical science is more emphasized overall treatment, and treating both the principal and secondary aspects of a disease puts prevention first, and Chinese medicine is few and famous with untoward reaction.Therefore, this sick Chinese medicine preparation of development treatment is highly significant with necessity.
Summary of the invention:
The object of the present invention is to provide a kind of oral medicine for the treatment of diabetes, responding well to treatment of existing in solution prior art is slow, Long-term taking medicine injures the problems such as very large to body and mind.
To achieve these goals, the present invention adopts following technical scheme to be:
Treat an oral medicine for diabetes, meter by weight, medicament consists of: Radix Rehmanniae 15-20 part, Fructus Lycii 15-20 part, 10~15 parts of Semen Astragali Complanatis, 15~20 parts of Fructus Corni, 5~10 parts, horse Flos Nelumbinis.
The oral medicine of described treatment diabetes, meter by weight, preferred agents consists of: 18 parts, the Radix Rehmanniae, 18 parts of Fructus Lycii, 12 parts of Semen Astragali Complanatis, 18 parts of Fructus Corni, 8 parts, horse Flos Nelumbinis.
The present invention treats the oral medicine of diabetes, and every secondary oral medicine is got 60-80 gram.When medicament uses, medicament is all put in pot, poured into clear water to all medicaments are flooded, intense fire boiled after 1-5 minute, decocted 15-20 minute with slow fire, poured out medicinal liquid; One auxiliary medicine agent decocts 2 times so repeatedly again, pours out medicinal liquid splendid attire respectively, and three times medicinal liquid divides under Morning Afternoon Evening clothes.
Pharmacology analysis of the present invention is as follows:
(1) Radix Rehmanniae, the rhizome of scrophulariaceae rehmannia glutinosa plant, sweet in the mouth and hardship, GUIXIN, liver, kidney channel, YIN nourishing and the production of body fluid promoting effect is thirsty for Tianjin wound, and interior-heat is quenched one's thirst.
(2) Fructus Lycii, modern pharmacology studies confirm that Fructus Lycii scalable body's immunity, can effectively suppress tumor growth and cell mutation, has slow down aging, the effect of anti-fatty liver, adjusting blood fat and the aspect such as blood glucose, promotion hemopoietic function, and is applied to clinical.Wolfberry fruit extract can significantly and lastingly reduce rat blood sugar, increase carbohydrate tolerance, and toxicity is less.
(3) Semen Astragali Complanati, can protect liver glycogen accumulation, blood fat reducing, falls enzyme; Energy decreased heart rate, reduces blood pressure, and increases cerebral blood flow; Can improve hemorheology index, suppress platelet aggregation; Energy enhancing human body immunity power, improves body specificity and non-specific immunity.
(4) Fructus Corni, there is diabetes effect, cornusol extract has obvious hypoglycemic activity to alloxan and the sick rat of epinephrine glycosuria, and the diabetes rat that streptozotocin (STZ) is formed also has similar effect.But normal rat blood sugar is had no significant effect, and prompting Fructus Corni has certain therapeutical effect to insulin-dependent diabetes patient.Experiment shows: Fructus Corni powder, ether extract and the ursolic acid further separating all can reduce blood glucose, glucose in urine, amount of drinking water and voided volume significantly, illustrate that ursolic acid is Fructus Corni diabetes active component.
(5) horse Flos Nelumbinis, salty in the mouth, acid, micro-hardship, cool in nature, can heat-clearing and toxic substances removing, hemostasis diuresis.
Beneficial effect of the present invention:
1, the present invention is adopting on the basis of traditional blood sugar lowering therapy, aspect treatment diabetes, has supplementing QI and nourishing YIN, and hypoglycemic effect, falls in replenishing body fluid and clearing away heat pathogen, and blood glucose, glucose in urine are effectively controlled.
2, adopt in the present invention one week, the scope that can reach normal fasting glucose is 3.15~6.19mmol/L, post-prandial glycemia 2 hours blood glucose < 7.8mmol/L.
Detailed description of the invention:
Embodiment 1
In the present embodiment, the consisting of of medicament: 15 grams, the Radix Rehmanniae, 20 grams of Fructus Lycii, 10 grams of Semen Astragali Complanatis, 20 grams of Fructus Corni, 5 grams, horse Flos Nelumbinis.Medicament use procedure is as follows:
Above medicament is all put in pot, poured into clear water to not having medicament dark to one-inch, intense fire boiled after 2 minutes, decocted 15-20 minute with slow fire, poured out medicinal liquid; One auxiliary medicine agent decocts 2 times so repeatedly again, pours out medicinal liquid splendid attire respectively, and three times medicinal liquid divides under Morning Afternoon Evening clothes.
Clinic Case:
Zhang, man, 46 years old, police, long-term irregular life and work, was diagnosed as diabetes before 5 years, successively took various pharmaceutical treatments, after have start injection insulin, cause the conversion of heavy psychological burden and physiology.At the beginning of 2010 9 months, start to take the present embodiment after 1, three day, record blood glucose target and drop to 6.0 mM/ls from 12.5 mM/ls, normal, so far not repeatedly.
Embodiment 2
In the present embodiment, the consisting of of medicament: 20 grams, the Radix Rehmanniae, 15 grams of Fructus Lycii, 15 grams of Semen Astragali Complanatis, 15 grams of Fructus Corni, 10 grams, horse Flos Nelumbinis.Medicament use procedure is as follows:
Above medicament is all put in pot, poured into clear water to not having medicament dark to one-inch, intense fire boiled after 2 minutes, decocted 15-20 minute with slow fire, poured out medicinal liquid; One auxiliary medicine agent decocts 2 times so repeatedly again, pours out medicinal liquid splendid attire respectively, and three times medicinal liquid divides under Morning Afternoon Evening clothes.
Clinic Case:
Guo so-and-so, man, 65 years old, workman, due to life stress, worry get angry, the tested diabetes of finding, psychology and physiology all there are great changes, all day is dispirited, depressed, household extremely worries; In August, 2008, according to patient's practical situation, allow it take the present embodiment 2.After three days, patient feels there has been from head to foot vigor, and energy rises, and walks energetically, and actual measurement blood glucose target drops to 5.8 mM/ls from 15.6 mM/ls, and physical recovery is good, so far not repeatedly.
Embodiment 3
In the present embodiment, the consisting of of medicament: 18 grams, the Radix Rehmanniae, 18 grams of Fructus Lycii, 12 grams of Semen Astragali Complanatis, 18 grams of Fructus Corni, 6 grams, horse Flos Nelumbinis.Medicament use procedure is as follows:
Above medicament is all put in pot, poured into clear water to not having medicament dark to one-inch, intense fire boiled after 2 minutes, decocted 15-20 minute with slow fire, poured out medicinal liquid; One auxiliary medicine agent decocts 2 times so repeatedly again, pours out medicinal liquid splendid attire respectively, and three times medicinal liquid divides under Morning Afternoon Evening clothes.
Clinic Case:
Zhao so-and-so, female, 52 years old, teacher, diabetes are found in unit routine physical examination in 2005, rear beginning Long-term taking medicine and use insulin, but the state of an illness runs down, and starts to occur blurred vision for 2009; Summer in 2010, is used the present embodiment after 3, three days, the listless disappearance of asthenia, and energy starts plentifully, and vision starts to recover, and actual measurement blood glucose target drops to the normal value of 5.7 mM/ls from 12.8 mM/ls, and patient is very pleased, so far less than not repeatedly.

Claims (2)

1. an oral medicine for the treatment of diabetes, is characterized in that, meter by weight, and medicament consists of: Radix Rehmanniae 15-20 part, Fructus Lycii 15-20 part, 10 ~ 15 parts of Semen Astragali Complanatis, 15 ~ 20 parts of Fructus Corni, 5 ~ 10 parts, horse Flos Nelumbinis.
2. according to the oral medicine for the treatment of diabetes claimed in claim 1, it is characterized in that, meter by weight, preferred agents consists of: 18 parts, the Radix Rehmanniae, 18 parts of Fructus Lycii, 12 parts of Semen Astragali Complanatis, 18 parts of Fructus Corni, 8 parts, horse Flos Nelumbinis.
CN201110166608.8A 2011-06-20 2011-06-20 Medicine for oral use for treating diabetes Expired - Fee Related CN102716276B (en)

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Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103142780B (en) * 2013-04-01 2016-03-02 中国人民解放军军事医学科学院毒物药物研究所 Extract, the Preparation Method And The Use of a kind of horse lotus seed or horse lotus seed skin
CN104689008A (en) * 2015-03-13 2015-06-10 郁莉 Medicine for treating diabetes, preparation method and detection method thereof
CN105943823A (en) * 2016-05-24 2016-09-21 成都市斯贝佳科技有限公司 Traditional Chinese medicine composition for treating diabetes
CN108465039A (en) * 2018-06-28 2018-08-31 黄建平 A kind of drug and preparation method thereof for treating diabetes

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1483422A (en) * 2002-09-19 2004-03-24 张利鹏 Medicine for treating diabetes
CN101708295A (en) * 2009-12-04 2010-05-19 卢速江 Chinese medicinal preparation for treating diabetes and preparation methods thereof
CN102274447A (en) * 2011-08-27 2011-12-14 赵国辉 Medicinal composition for treating diabetes

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1483422A (en) * 2002-09-19 2004-03-24 张利鹏 Medicine for treating diabetes
CN101708295A (en) * 2009-12-04 2010-05-19 卢速江 Chinese medicinal preparation for treating diabetes and preparation methods thereof
CN102274447A (en) * 2011-08-27 2011-12-14 赵国辉 Medicinal composition for treating diabetes

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
《马兰叶中黄酮的不同提取方法比较》;姜显光 等;《现代农业科技》;20101231(第16期);第21页左栏第1段 *
周安方.《中医药治疗糖尿周安方病文献综述(二)》.《湖北中医杂志》.1980,第47页左栏第1行—右栏第13行. *
姜显光 等.《马兰叶中黄酮的不同提取方法比较》.《现代农业科技》.2010,(第16期),第21页左栏第1段.

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