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CN102688383B - Traditional Chinese medicine composite for treating body surface ulcer or fester - Google Patents

Traditional Chinese medicine composite for treating body surface ulcer or fester Download PDF

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CN102688383B
CN102688383B CN2011104330153A CN201110433015A CN102688383B CN 102688383 B CN102688383 B CN 102688383B CN 2011104330153 A CN2011104330153 A CN 2011104330153A CN 201110433015 A CN201110433015 A CN 201110433015A CN 102688383 B CN102688383 B CN 102688383B
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ulcer
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CN102688383A (en
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李艳
路西明
杜景霞
冯建芳
王建刚
李瑞芳
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Henan University of Science and Technology
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Abstract

The invention belongs to the technical field of traditional Chinese medicine, and particularly discloses a traditional Chinese medicine composite for treating the body surface ulcer or fester. The traditional Chinese medicine composite for treating the body surface ulcer or fester is prepared by the following raw materials in parts by weight: 5-10 parts of muschus, 25-50 parts of borneol, 100-200 parts of daemonorops draco, 100-200 parts of rhizoma bletillae, 100-200 parts of coptis chinensis and 100-200 parts of indigo naturalis. The traditional Chinese medicine composite for treating the body surface ulcer or fester provided by the invention can quickly relieve and effectively cure the varicose ulcer, the ulcer caused by the bedsore, the ecthyma leg, the furuncle and the carbuncle, the body surface ulcer caused by the poor healing of operative incision, the wound, the poor wound healing, the wound hemostasis and the like or the chronic ulcer, can quickly relieve and eliminate the clinical symptoms such as the red, the swell, the hot and the pain, and has the advantages of being quick in becoming effective, exact in curative effect, and free of side effects.

Description

一种用于治疗体表溃疡或溃烂的中药组合物A kind of traditional Chinese medicine composition for treating body surface ulcer or ulceration

技术领域 technical field

本发明涉及中药技术领域,具体涉及一种用于治疗体表溃疡或溃烂的中药组合物。The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating body surface ulcers or ulcers.

背景技术 Background technique

体表溃疡或溃烂主要包括:臁疮腿、小腿静脉曲张性溃疡、手术切口愈合不良、褥疮、感染创面久治不愈等疾病,属疑难杂症。该病虽然危及生命的可能性不大,但久治不愈实属常见。患者几乎都有四处求医、劳神伤财、甚至被人欺骗的经历,其结果多是失望大于希望。同时,体表溃疡或溃烂的局部常有异味分泌物不停的外溢,不但极易招致新的感染,而且严重影响了病人的卫生,甚至遭到他人的厌恶。Ulcers or ulcers on the body surface mainly include: ecchymosis legs, varicose ulcers of the lower legs, poor healing of surgical incisions, decubitus ulcers, infected wounds and other diseases that cannot be cured for a long time, which are difficult and miscellaneous diseases. Although the disease is unlikely to be life-threatening, it is not uncommon for the disease to persist for a long time. Patients almost all have the experience of seeking medical treatment everywhere, wasting their minds and money, and even being deceived by others. The results are mostly disappointment than hope. At the same time, the part of body surface ulcer or fester often has peculiar smell secretion overflowing constantly, which not only easily leads to new infection, but also seriously affects the hygiene of the patient, and is even disgusted by others.

体表溃疡或溃烂疾病的西医治疗方法主要是:保持创面清洁,定期更换消毒纱巾。西医治疗方法的疗效欠佳或几乎无效。中医药治疗的方药较多,具有一定的疗效,但大多存在疗效不佳、疗程太长的缺点,有的疗程甚至要长达半年左右。The Western medicine treatment method of body surface ulcer or festering disease mainly is: keep the wound surface clean, change the sterile gauze regularly. Western medical treatment methods have little or no effect. There are many prescriptions and medicines for Chinese medicine treatment, which have certain curative effects, but most of them have the disadvantages of poor curative effect and too long course of treatment, and some courses of treatment even take as long as about half a year.

发明内容 Contents of the invention

本发明的目的是提供一种治愈率高、疗程短的用于治疗体表溃疡或溃烂的中药组合物。The object of the present invention is to provide a traditional Chinese medicine composition for treating body surface ulcer or ulceration with high cure rate and short course of treatment.

为了实现以上目的,本发明所采用的技术方案是:一种用于治疗体表溃疡或溃烂的中药组合物,由以下重量份数的原料药制成:人工麝香5-10份、冰片25-50份、血竭100-200份、白及100-200份、黄连100-200份、青黛100-200份。In order to achieve the above object, the technical solution adopted in the present invention is: a traditional Chinese medicine composition for treating body surface ulcer or festering, made of the following raw materials in parts by weight: artificial musk 5-10 parts, borneol 25- 50 parts, 100-200 parts of dried blood, 100-200 parts of Baiji, 100-200 parts of Coptis chinensis, and 100-200 parts of Qingdai.

优选的,用于治疗体表溃疡或溃烂的中药组合物由以下重量份数的原料药制成:人工麝香5-10份、冰片25-30份、血竭100-120份、白及100-120份、黄连100-120份、青黛100-120份。Preferably, the traditional Chinese medicine composition for treating body surface ulcers or festers is made of the following raw materials in parts by weight: 5-10 parts of artificial musk, 25-30 parts of borneol, 100-120 parts of dried blood, 100- 120 parts, Coptidis 100-120 parts, Qingdai 100-120 parts.

更优选的,用于治疗体表溃疡或溃烂的中药组合物由以下重量份数的原料药制成:人工麝香5份、冰片25份、血竭100份、白及100份、黄连100份、青黛100份。More preferably, the traditional Chinese medicine composition for treating body surface ulcers or ulcers is made of the following raw materials in parts by weight: 5 parts of artificial musk, 25 parts of borneol, 100 parts of blood, 100 parts of white root, 100 parts of coptis, Qingdai 100 parts.

所述用于治疗体表溃疡或溃烂的中药组合物为散剂,其制备方法为:按重量份数称取原料药人工麝香、冰片、血竭、白及、黄连、青黛,将人工麝香研磨粉碎,将冰片、血竭、白及、黄连和青黛粉碎后过200目筛,之后混匀,分装,制成散剂。The traditional Chinese medicine composition for treating body surface ulcers or festers is a powder, and its preparation method is as follows: weighing the raw materials artificial musk, borneol, blood jellyfish, bletilla, coptis, and indigo naturalis in parts by weight, grinding and pulverizing the artificial musk , pulverize borneol, dried blood, bletilla, coptis and indigo daisy, pass through a 200-mesh sieve, then mix well, pack separately, and make powder.

本发明提供的用于治疗体表溃疡或溃烂的中药组合物各原料药的功能介绍如下。The function of each raw material of the traditional Chinese medicine composition for treating body surface ulcer or ulcer provided by the present invention is introduced as follows.

人工麝香:味辛,性温;归心、肝、脾经。具有开窍醒神、活血通经、散结止痛之功效。其性辛香走窜,内而脏腑筋骨,外而肌肤毛窍,无所不达。主要用于温热病邪陷心包、神志昏迷;小儿惊痫、痉厥抽搐;中风、痰厥、气郁暴厥、猝然倒仆、牙关紧闭,以及心腹急痛、癥瘕积聚、痈疽恶疮、跌打损伤等证。广泛用治痈疽恶疮、结核肿毒、跌打损伤、瘀肿疼痛。Artificial musk: pungent in taste, warm in nature; Guixin, liver, spleen meridians. It has the effects of resuscitating the mind, promoting blood circulation and stimulating the menstrual flow, dispelling stagnation and relieving pain. Its property is pungent and fragrant, and it reaches the viscera, muscles and bones inside, and the skin and hair openings outside, reaching everywhere. Mainly used for febrile disease pathogenic trapping in the pericardium, coma; convulsions, convulsions and convulsions in children; Sores, bruises, etc. It is widely used to treat carbuncle and malignant sore, tuberculosis, bruises, bruises and pain.

冰片:味辛,性寒,有通诸窍、散郁火,消肿去翳之功效。用于疮疡肿痛,溃后不敛,有清热解毒、防腐生肌作用。Borneol: pungent in taste, cold in nature, has the effects of clearing all orifices, dispelling stagnant fire, reducing swelling and removing nebula. It is used for swelling and pain of sores, does not hold back after ulceration, and has the functions of clearing away heat and detoxifying, antiseptic and promoting granulation.

血竭:性甘、咸,平。归肝经。具有活血定痛,化瘀止血,敛疮生肌的功效。疮疡不敛,本品外用,有敛疮生肌之功,可用治疮疡久溃不敛之证。Dried Blood: sweet, salty, flat. Return liver channel. It has the effects of promoting blood circulation and relieving pain, removing blood stasis and stopping bleeding, suppressing sores and promoting granulation. Sores and ulcers are not restrained, this product is used externally, it has the function of restraining sores and promoting granulation, and can be used to treat the syndrome of chronic ulcers and ulcers.

白及:味苦、甘、涩,性寒,归肺、胃。肝经。有收敛止血,消肿生肌之功,用于内外出血诸证及痈肿、烫伤、手足皲裂、肛裂等。Baiji: Bitter, sweet, astringent, cold in nature, returns to lung and stomach. liver meridian. It has the functions of astringing to stop bleeding, detumescence and promoting granulation. It is used for various syndromes of internal and external bleeding, carbuncle, scald, chapped hands and feet, anal fissure, etc.

黄连:苦,寒。归心,脾、胃、胆、大肠经。有清热燥湿,泻火解毒之功效。黄连既能清热燥湿,又能泻火解毒,尤善疗疔毒,外治湿疹、湿疮、耳道流脓。现代药理学研究表明黄连具有抗炎镇痛抗菌的作用。Coptidis: bitter, cold. GUIXIN, spleen, stomach, gallbladder, large intestine channel. It has the effects of clearing away heat and dampness, purging fire and detoxifying. Coptidis can not only clear away heat and dampness, but also purify fire and detoxify. It is especially good at treating furunculosis, externally treating eczema, eczema, and ear canal discharge. Modern pharmacological studies have shown that coptis has anti-inflammatory, analgesic and antibacterial effects.

青黛:性咸,寒。归肝、肺经。具有清热解毒,凉血消斑,清肝泻火,定惊之功效。现代药理学研究表明,青黛对金黄色葡萄球菌、炭疽杆菌、志贺氏痢疾杆菌、霍乱弧菌均有抗菌作用。Indigo Daisy: salty in nature, cold. Return liver, lung meridian. It has the effects of clearing away heat and detoxification, cooling blood and eliminating spots, clearing liver and purging fire, and calming convulsions. Modern pharmacological studies have shown that Qingdai has antibacterial effects on Staphylococcus aureus, Bacillus anthracis, Shigella Shigella, and Vibrio cholerae.

以上各原料药诸药合用,具有祛腐生肌,拔毒消肿的功效。本发明提供的用于治疗体表溃疡或溃烂的中药组合物可迅速缓解并有效治疗静脉曲张性溃烂、褥疮、臁疮腿、疖子和痈引起的溃疡、手术切口愈合不良、创伤、创伤愈合不良、创伤止血及其他原因引起的体表溃疡或久治不愈的溃烂,迅速缓解并消除红、肿、热、痛的临床症状,具有见效快,疗效确切,无毒副作用的优点。使用本发明提供的用于治疗体表溃疡或溃烂的中药组合物,较深的疮面或创面一般在1-4周可治愈,较浅的疮面或创面一般1周时间即可治愈。The combination of above raw materials and various medicines has the effects of dispelling putrefaction and promoting granulation, pulling out toxins and reducing swelling. The traditional Chinese medicine composition for treating body surface ulcers or ulcers provided by the invention can rapidly relieve and effectively treat ulcers caused by varicose ulcers, decubital ulcers, ecchymosis legs, boils and carbuncles, poor healing of surgical incisions, wounds, and poor wound healing It can quickly relieve and eliminate the clinical symptoms of redness, swelling, heat and pain caused by wounds, hemostasis and other reasons. Using the traditional Chinese medicine composition for treating body surface ulcers or ulcers provided by the invention, deep sores or wounds can be cured within 1-4 weeks, and shallow sores or wounds can be cured within 1 week.

具体实施方式 Detailed ways

实施例1Example 1

本实施例提供的用于治疗体表溃疡或溃烂的中药组合物由以下重量份数的原料药制成:人工麝香5份、冰片25份、血竭100份、白及100份、黄连100份、青黛100份。其为散剂,制备方法为:按重量份数称取原料药人工麝香、冰片、血竭、白及、黄连、青黛,将人工麝香研磨粉碎,将冰片、血竭、白及、黄连和青黛粉碎后过200目筛,之后混匀,分装,制成散剂,辐照消毒。The traditional Chinese medicine composition for treating body surface ulcers or ulcers provided in this example is made of the following raw materials in parts by weight: 5 parts of artificial musk, 25 parts of borneol, 100 parts of blood jellyfish, 100 parts of bletilla, and 100 parts of coptis , Qingdai 100 parts. It is a powder, and the preparation method is as follows: taking the raw materials artificial musk, borneol, blood jellyfish, bletilla, coptis and indigo naturalis in parts by weight, grinding and pulverizing the artificial musk, pulverizing the borneol, blood jelly, baiji, coptis and indigo naturalis Pass through a 200-mesh sieve, then mix evenly, pack separately, make powder, and sterilize by irradiation.

实施例2Example 2

本实施例提供的用于治疗体表溃疡或溃烂的中药组合物由以下重量份数的原料药制成:人工麝香10份、冰片50份、血竭120份、白及120份、黄连120份、青黛120份。其为散剂,制备方法同实施例1。The traditional Chinese medicine composition for treating body surface ulcers or festers provided in this example is made of the following raw materials in parts by weight: 10 parts of artificial musk, 50 parts of borneol, 120 parts of blood, 120 parts of bletilla, and 120 parts of coptis , Qingdai 120 parts. It is a powder, and its preparation method is the same as in Example 1.

实施例3Example 3

本实施例提供的用于治疗体表溃疡或溃烂的中药组合物由以下重量份数的原料药制成:人工麝香5份、冰片30份、血竭200份、白及200份、黄连200份、青黛200份。其为散剂,制备方法同实施例1。The traditional Chinese medicine composition for treating body surface ulcers or ulcers provided in this example is made of the following raw materials in parts by weight: 5 parts of artificial musk, 30 parts of borneol, 200 parts of blood, 200 parts of bletilla, and 200 parts of coptis , Qingdai 200 parts. It is a powder, and its preparation method is the same as in Example 1.

试验例实施例1-3提供的用于治疗体表溃疡或溃烂的中药组合物的临床疗效观察The clinical curative effect observation that is used for the treatment of the Chinese medicine composition of body surface ulcer or fester that test example embodiment 1-3 provides

随机抽取患者48例,其中臁疮腿患者12例,小腿静脉曲张溃疡患者15例,手术切口愈合不良患者21例。臁疮腿患者为A组,小腿静脉曲张溃疡患者为B组,手术切口愈合不良患者为C组。A组使用本发明实施例1提供的中药组合物进行治疗,B组使用本发明实施例2提供的中药组合物进行治疗,C组使用本发明实施例3提供的中药组合物进行治疗。A total of 48 patients were randomly selected, including 12 patients with leg ulcers, 15 patients with calf varicose ulcers, and 21 patients with poor healing of surgical incisions. Patients with leg ulcers were group A, patients with calf varicose ulcer were group B, and patients with poor surgical incision healing were group C. Group A was treated with the traditional Chinese medicine composition provided in Example 1 of the present invention, Group B was treated with the traditional Chinese medicine composition provided in Example 2 of the present invention, and Group C was treated with the traditional Chinese medicine composition provided in Example 3 of the present invention.

治疗方法:用药前,先用75%的酒精对创面进行消毒,然后用生理盐水冲洗创面,之后将本发明实施例提供的中药组合物均匀覆盖在创面上,渗出物较多的创面,在渗出的部位补充覆盖。Treatment method: before using the medicine, first disinfect the wound surface with 75% alcohol, then wash the wound surface with normal saline, and then evenly cover the wound surface with the traditional Chinese medicine composition provided by the embodiment of the present invention. Replenishes coverage in areas that ooze.

疗效判断标准:痊愈,即溃疡完全消失,结痂自行脱落。Criteria for judging the curative effect: recovery, that is, the ulcer completely disappears and the scab falls off automatically.

临床治疗情况观察:大多数患者创面在一天左右结痂,溃疡面较浅的患者创面结痂后1周左右可痊愈,溃疡面较深的患者创面需要多次清创上药直至结痂自行脱落而痊愈。具体临床疗效统计数据见表1所示。Observation of clinical treatment: wounds of most patients scabbed within a day or so, patients with shallow ulcers could heal within a week after scabs formed, and wounds of patients with deep ulcers needed multiple debridements and medications until the scabs fell off on their own And healed. The specific clinical efficacy statistics are shown in Table 1.

表1各实施例中药组合物的临床疗效统计数据The clinical curative effect statistical data of each embodiment Chinese medicine composition of table 1

Figure BDA0000122968340000041
Figure BDA0000122968340000041

从表1中可以看出,实施例1-3提供的用于治疗体表溃疡或溃烂的中药组合物的临床治愈率为100%,疗程最长的为3周,2周的治愈率为93.7%,1周的治愈率为54.1%。As can be seen from Table 1, the clinical cure rate of the Chinese medicine composition for the treatment of body surface ulcer or ulceration provided by embodiment 1-3 is 100%, the longest course of treatment is 3 weeks, and the cure rate in 2 weeks is 93.7% %, the 1-week cure rate was 54.1%.

典型病例Typical cases

病例1:安某,男,63岁,河南科技大学后勤集团职工。1996年3月23日,在校医院用激光烧掉左脚趾拇指的鸡眼后创面经久不愈,西医治疗不但无效,并且溃疡面加大加深,暴漏骨头。溃疡持续2个月后到我处治疗,使用本发明实施例1提供的中药组合物进行治疗,17天结痂自行脱落创面痊愈。Case 1: An Mou, male, 63 years old, employee of the Logistics Group of Henan University of Science and Technology. On March 23, 1996, the corn on the left toe and big toe was burnt with laser at the school hospital. The wound did not heal for a long time. Ulcer lasted for 2 months and came to our place for treatment, using the Chinese medicine composition provided by the embodiment of the present invention 1 for treatment, and the scab fell off automatically in 17 days and the wound surface recovered from illness.

病例2:路某,男,28岁,嵩县九店石黄人。1998年5月,患者在农田劳动时被锐气刺伤右脚底,经西医治疗半年无效,溃疡较深,分泌物较多,几乎不能行走。1998年年底到我处治疗,使用本发明实施例3提供的中药组合物进行治疗,20天完全治愈。Case 2: Lu X, male, 28 years old, from Shihuang, Jiudian, Song County. In May 1998, the patient was stabbed by Rui Qi on the sole of his right foot while working in the farmland. After half a year of Western medicine treatment, the ulcer was deep and the secretion was heavy, and he could hardly walk. Come to our treatment at the end of 1998, use the Chinese medicine composition that the embodiment of the present invention 3 provides to treat, 20 days complete cure.

病例3:张某,男,68岁,洛阳起重器厂职工。患者双下肢严重静脉曲张,2000年4月,骑自行车时右下肢撞伤而形成溃疡,先后在洛阳几家大医院诊治3年之久,花费几千元,溃疡始终不愈。后到我处治疗,使用本发明实施例2提供的中药组合物进行治疗,1周即愈。后来此人左下肢又出现创伤不愈,同样使用本发明实施例2提供的中药组合物进行治疗,11天溃疡愈合。Case 3: Zhang, male, 68 years old, employee of Luoyang Crane Factory. The patient had severe varicose veins in both lower limbs. In April 2000, he injured his right lower limb while riding a bicycle and formed an ulcer. He was diagnosed and treated in several large hospitals in Luoyang for 3 years, costing several thousand yuan, but the ulcer never healed. Back to my place for treatment, use the Chinese medicine composition that the embodiment of the present invention 2 provides to treat, promptly heal within 1 week. Later, the person's left lower limb suffered from unhealed wounds, which were also treated with the traditional Chinese medicine composition provided in Example 2 of the present invention, and the ulcers healed within 11 days.

Claims (4)

1.一种用于治疗体表溃疡或溃烂的中药组合物,其特征在于,由以下重量份数的原料药制成:人工麝香5-10份、冰片25-50份、血竭100-200份、白及100-200份、黄连100-200份、青黛100-200份。1. A Chinese medicine composition for treating body surface ulcer or festering, is characterized in that, is made of the crude drug of following parts by weight: 5-10 parts of artificial musk, 25-50 parts of borneol, 100-200 parts of dried blood 100-200 parts of Baiji, 100-200 parts of Coptis chinensis, and 100-200 parts of Qingdai. 2.根据权利要求1所述的用于治疗体表溃疡或溃烂的中药组合物,其特征在于,由以下重量份数的原料药制成:人工麝香5-10份、冰片25-30份、血竭100-120份、白及100-120份、黄连100-120份、青黛100-120份。2. the Chinese medicine composition that is used for the treatment of body surface ulcer or ulceration according to claim 1, is characterized in that, is made of the crude drug of following parts by weight: artificial musk 5-10 parts, borneol 25-30 parts, 100-120 parts of dried blood, 100-120 parts of Baiji, 100-120 parts of Coptis chinensis, and 100-120 parts of Qingdai. 3.根据权利要求2所述的用于治疗体表溃疡或溃烂的中药组合物,其特征在于,由以下重量份数的原料药制成:人工麝香5份、冰片25份、血竭100份、白及100份、黄连100份、青黛100份。3. The traditional Chinese medicine composition for treating body surface ulcer or festering according to claim 2, characterized in that, it is made of the following raw materials in parts by weight: 5 parts of artificial musk, 25 parts of borneol, 100 parts of dried blood , 100 parts of Baiji, 100 parts of Coptis chinensis, and 100 parts of Qingdai. 4.根据权利要求1-3任一所述的用于治疗体表溃疡或溃烂的中药组合物,其特征在于,所述中药组合物为散剂。4. The traditional Chinese medicine composition for treating body surface ulcer or fester according to any one of claims 1-3, characterized in that, the traditional Chinese medicine composition is a powder.
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CN104689075B (en) * 2015-03-13 2017-12-29 郝玉梅 Treat the united medicine of Chinese and Western medicine of pressure sore
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