CN102670737B - Traditional Chinese medicine oral liquid for relieving iron deficiency anemia and preparation method thereof - Google Patents
Traditional Chinese medicine oral liquid for relieving iron deficiency anemia and preparation method thereof Download PDFInfo
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- 239000003814 drug Substances 0.000 title claims abstract description 26
- 239000007788 liquid Substances 0.000 title claims abstract description 20
- 208000015710 Iron-Deficiency Anemia Diseases 0.000 title claims abstract description 16
- 238000002360 preparation method Methods 0.000 title claims description 6
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 claims abstract description 12
- 235000003140 Panax quinquefolius Nutrition 0.000 claims abstract description 12
- 235000008434 ginseng Nutrition 0.000 claims abstract description 12
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 50
- 239000000706 filtrate Substances 0.000 claims description 20
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 15
- 241000208340 Araliaceae Species 0.000 claims description 11
- 241000222336 Ganoderma Species 0.000 claims description 11
- 239000012567 medical material Substances 0.000 claims description 10
- 238000004064 recycling Methods 0.000 claims description 10
- 239000007787 solid Substances 0.000 claims description 10
- 238000003756 stirring Methods 0.000 claims description 10
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims description 5
- 229930006000 Sucrose Natural products 0.000 claims description 5
- 230000002421 anti-septic effect Effects 0.000 claims description 5
- 235000012907 honey Nutrition 0.000 claims description 5
- 239000000047 product Substances 0.000 claims description 5
- 230000001954 sterilising effect Effects 0.000 claims description 5
- 238000004659 sterilization and disinfection Methods 0.000 claims description 5
- 239000011550 stock solution Substances 0.000 claims description 5
- 239000005720 sucrose Substances 0.000 claims description 5
- 208000007502 anemia Diseases 0.000 abstract description 8
- 208000024891 symptom Diseases 0.000 abstract description 6
- 208000002173 dizziness Diseases 0.000 abstract description 5
- 208000009205 Tinnitus Diseases 0.000 abstract description 2
- 231100000886 tinnitus Toxicity 0.000 abstract description 2
- 206010015137 Eructation Diseases 0.000 abstract 1
- 240000008397 Ganoderma lucidum Species 0.000 abstract 1
- 235000001637 Ganoderma lucidum Nutrition 0.000 abstract 1
- 206010028813 Nausea Diseases 0.000 abstract 1
- 244000131316 Panax pseudoginseng Species 0.000 abstract 1
- 240000001341 Reynoutria japonica Species 0.000 abstract 1
- 235000018167 Reynoutria japonica Nutrition 0.000 abstract 1
- 241000304195 Salvia miltiorrhiza Species 0.000 abstract 1
- 235000011135 Salvia miltiorrhiza Nutrition 0.000 abstract 1
- 241000913745 Spatholobus Species 0.000 abstract 1
- 208000022531 anorexia Diseases 0.000 abstract 1
- 206010061428 decreased appetite Diseases 0.000 abstract 1
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- 230000000694 effects Effects 0.000 description 9
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- 239000008280 blood Substances 0.000 description 6
- 210000004369 blood Anatomy 0.000 description 6
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Abstract
The invention discloses a traditional Chinese medicine oral liquid for relieving iron deficiency anemia, which is prepared with the following materials in part by weight: 200 to 400 parts of suberect spatholobus stem, 100 to 200 parts of ginseng, 200 to 400 parts of fleeceflower root, 100 to 200 parts of rhizoma atractylodis, 100 to 200 parts of salvia miltiorrhiza and 100 to 200 parts of ganoderma lucidum. The oral liquid can relieve concomitant dizziness and tinnitus, sallow and pale complexion, weakness, anorexia, nausea and eructation caused by iron deficiency anemia and improve the anemic symptom, has remarkable efficacy, and is worth popularizing and applying clinically.
Description
Technical field
The invention belongs to the field of Chinese medicines, particularly a kind of Chinese medicine oral liquid and preparation method of alleviating iron deficiency anemia.
Background technology
Current Chinese iron deficiency anemia incidence rate is higher, and wherein women, child are group of people at high risk.Children anemia rate is in 25% left and right, and women anemia rate is in 20% left and right, and anemia of pregnant woman's anemia rate is up to 35%, and man's anemia rate is in 10% left and right.Also some old people is because Deficiency of Intake easily causes iron deficiency anemia, and Chinese medicine is used for the treatment of the medicine of iron deficiency anemia, owing to having little, the eutherapeutic feature of side effect, therefore favored by people.
Summary of the invention
The object of the present invention is to provide that a kind of side effect is little, good effect, for alleviating Chinese medicine oral liquid and the preparation method of iron deficiency anemia.
For achieving the above object, the present invention is achieved by the following technical solutions:
The Chinese medicine oral liquid of alleviating iron deficiency anemia is to be made by the crude drug of following parts by weight:
Caulis Spatholobi 200-400 part, Radix Ginseng 100-200 part, Radix Polygoni Multiflori 200-400 part, Rhizoma Atractylodis 100-200 part, Radix Salviae Miltiorrhizae 100-200 part, Ganoderma 100-200 part.
The Chinese medicine oral liquid of described alleviation iron deficiency anemia is to be made by the crude drug of following parts by weight:
300 parts of Caulis Spatholobis, 150 parts of Radix Ginsengs, 300 parts of Radix Polygoni Multiflori, 150 parts of Rhizoma Atractylodis, 150 parts of Radix Salviae Miltiorrhizaes, 150 parts of Ganodermas.
Chinese medicine oral liquid and the preparation method of described alleviation iron deficiency anemia, comprise the following steps:
A, get 300 parts of Caulis Spatholobis, 300 parts of Radix Polygoni Multiflori, 150 parts of Rhizoma Atractylodis, water decocts secondary, and each water consumption is 10 times of amounts of medical material weight, decocts secondary, each 1-2 hour, filters, and filtrate is condensed at 60 ℃ and surveys the clear paste that relative density is 1.10-1.25, adding ethanol is 60% to making containing amount of alcohol, stirs evenly, standing, filter, get filtrate recycling ethanol, be condensed into the extractum containing solid weight 65-67%, obtain extractum A;
B, get 150 parts of 150 parts of Radix Ginsengs, 150 parts of Radix Salviae Miltiorrhizaes, Ganoderma and be ground into 15 orders, each water consumption is 5 times of amounts of medical material weight, decocts secondary, each 1-2 hour, filter, filtrate is condensed at 60 ℃ and surveys the clear paste that relative density is 1.10-1.25, and adding ethanol is 60% to making containing amount of alcohol, stir evenly, standing, filter, get filtrate recycling ethanol, be condensed into the extractum containing solid weight 65-67%, obtain extractum B;
C, described extractum A and described extractum B are according to volume ratio 1:1, and merging mixes, and adds sucrose 20%, refined honey 12%, antiseptic 1-3%, stock solution embedding, and irradiation sterilization, packed products, makes oral liquid, obtains.
Usage and dosage: oral, 15ml/ time, every day 3 times, a month course for the treatment of, after taking medicine, how at 15 days, to take effect, cure 2-6 the course for the treatment of.This Chinese medicine oral liquid feature is that to make patient fully recover effective, and toxic and side effects is little, plays the not stagnant heresy for the treatment of both the principal and secondary aspects of a disease, righting, does not eliminating evilly hinder positive effect, and without recurrence, cost is low, and clinic is applied.
In the selected raw material of Chinese medicine of the present invention, Caulis Spatholobi: bitter, micro-sweet, warm, return Liver Channel, blood circulation promoting and enriching, relaxing muscles and tendons and activating QI and blood in the collateral; Radix Ginseng: sweet, micro-hardship, flat, return spleen, lung, heart channel, strongly invigorating primordial QI, multiple arteries and veins are admittedly de-, invigorating the spleen to benefit the lung, promote the production of body fluid, calm the nerves; Radix Polygoni Multiflori: bitter, sweet, puckery, tepor, return liver, kidney channel, enrich and benefit essence and blood; Rhizoma Atractylodis: acrid, bitter, warm, return spleen, stomach warp, drying damp and strengthening spleen; Radix Salviae Miltiorrhizae: bitter, be slightly cold, GUIXIN, pericardium, Liver Channel, blood circulation promoting and blood stasis dispelling, removing heat from blood eliminating carbuncle, nourishing blood to tranquillize the mind; Ganoderma: sweet, flat, GUIXIN, lung, liver, kidney channel, invigorating QI and tranquilization; All medicines are supported mutually, the function that there is invigorating the spleen and replenishing QI, enriches blood and invigorate blood circulation, oral liquid of the present invention can alleviate due to iron deficiency anemia follow that dizziness and tinnitus, shallow complexion are pale, fatigue and weakness, loss of appetite, the belch of feeling sick, improve Anemia, evident in efficacy, clinic is applied.Points for attention: anemia of pregnant woman's forbidding.
The specific embodiment
Embodiment 1:
Crude drug: 300 parts of Caulis Spatholobis, 150 parts of Radix Ginsengs, 300 parts of Radix Polygoni Multiflori, 150 parts of Rhizoma Atractylodis, 150 parts of Radix Salviae Miltiorrhizaes, 150 parts of Ganodermas.
Method for making: A, get 300 parts of Caulis Spatholobis, 300 parts of Radix Polygoni Multiflori, 150 parts of Rhizoma Atractylodis, water decocts secondary, and each water consumption is 10 times of amounts of medical material weight, decocts secondary, each 1-2 hour, filters, and filtrate is condensed at 60 ℃ and surveys the clear paste that relative density is 1.10-1.25, adding ethanol is 60% to making containing amount of alcohol, stirs evenly, standing, filter, get filtrate recycling ethanol, be condensed into the extractum containing solid weight 65-67%, obtain extractum A;
B, get 150 parts of 150 parts of Radix Ginsengs, 150 parts of Radix Salviae Miltiorrhizaes, Ganoderma and be ground into 15 orders, each water consumption is 5 times of amounts of medical material weight, decocts secondary, each 1-2 hour, filter, filtrate is condensed at 60 ℃ and surveys the clear paste that relative density is 1.10-1.25, and adding ethanol is 60% to making containing amount of alcohol, stir evenly, standing, filter, get filtrate recycling ethanol, be condensed into the extractum containing solid weight 65-67%, obtain extractum B;
C, described extractum A and described extractum B are according to volume ratio 1:1, and merging mixes, and adds sucrose 20%, refined honey 12%, antiseptic 1-3%, stock solution embedding, and irradiation sterilization, packed products, makes oral liquid, obtains.Usage and dosage: oral, 15ml/ time, every day 3 times.
Embodiment 2:
Crude drug: 400 parts of Caulis Spatholobis, 200 parts of Radix Ginsengs, 400 parts of Radix Polygoni Multiflori, 200 parts of Rhizoma Atractylodis, 200 parts of Radix Salviae Miltiorrhizaes, 200 parts of Ganodermas.
Method for making: A, get 400 parts of Caulis Spatholobis, 400 parts of Radix Polygoni Multiflori, 200 parts of Rhizoma Atractylodis, water decocts secondary, and each water consumption is 10 times of amounts of medical material weight, decocts secondary, each 1-2 hour, filters, and filtrate is condensed at 60 ℃ and surveys the clear paste that relative density is 1.10-1.25, adding ethanol is 60% to making containing amount of alcohol, stirs evenly, standing, filter, get filtrate recycling ethanol, be condensed into the extractum containing solid weight 65-67%, obtain extractum A;
B, get 200 parts of 200 parts of Radix Ginsengs, 200 parts of Radix Salviae Miltiorrhizaes, Ganoderma and be ground into 15 orders, each water consumption is 5 times of amounts of medical material weight, decocts secondary, each 1-2 hour, filter, filtrate is condensed at 60 ℃ and surveys the clear paste that relative density is 1.10-1.25, and adding ethanol is 60% to making containing amount of alcohol, stir evenly, standing, filter, get filtrate recycling ethanol, be condensed into the extractum containing solid weight 65-67%, obtain extractum B;
C, described extractum A and described extractum B are according to volume ratio 1:1, and merging mixes, and adds sucrose 20%, refined honey 12%, antiseptic 1-3%, stock solution embedding, and irradiation sterilization, packed products, makes oral liquid, obtains.Usage and dosage: oral, 15ml/ time, every day 3 times.
Embodiment 3:
Crude drug: 200 parts of Caulis Spatholobis, 100 parts of Radix Ginsengs, 200 parts of Radix Polygoni Multiflori, 100 parts of Rhizoma Atractylodis, 100 parts of Radix Salviae Miltiorrhizaes, 100 parts of Ganodermas.
Method for making: A, get 200 parts of Caulis Spatholobis, 200 parts of Radix Polygoni Multiflori, 100 parts of Rhizoma Atractylodis, water decocts secondary, and each water consumption is 10 times of amounts of medical material weight, decocts secondary, each 1-2 hour, filters, and filtrate is condensed at 60 ℃ and surveys the clear paste that relative density is 1.10-1.25, adding ethanol is 60% to making containing amount of alcohol, stirs evenly, standing, filter, get filtrate recycling ethanol, be condensed into the extractum containing solid weight 65-67%, obtain extractum A;
B, get 100 parts of 100 parts of Radix Ginsengs, 100 parts of Radix Salviae Miltiorrhizaes, Ganoderma and be ground into 15 orders, each water consumption is 5 times of amounts of medical material weight, decocts secondary, each 1-2 hour, filter, filtrate is condensed at 60 ℃ and surveys the clear paste that relative density is 1.10-1.25, and adding ethanol is 60% to making containing amount of alcohol, stir evenly, standing, filter, get filtrate recycling ethanol, be condensed into the extractum containing solid weight 65-67%, obtain extractum B;
C, described extractum A and described extractum B are according to volume ratio 1:1, and merging mixes, and adds sucrose 20%, refined honey 12%, antiseptic 1-3%, stock solution embedding, and irradiation sterilization, packed products, makes oral liquid, obtains.Usage and dosage: oral, 15ml/ time, every day 3 times.
Embodiment 4:
Clinical trial
The present invention is through carrying out clinical treatment observation to 60 routine Patients with iron deficiency anemia, male's 20 examples wherein, and women's 40 examples, the age 18 is by 60 years old, and symptom is pale complexion, dizziness, dark and dim eyesight, weak, tachypnea, cardiopalmus etc.
(1) Therapeutic Method: oral embodiment 1 Chinese medicine oral liquid, 15ml/ time, every day 3 times, a month course for the treatment of.
(2) efficacy assessment standard:
Cure: clinical symptoms sign disappears, it is normal that functional activity recovers.
Effective: the basic or large portion of clinical symptoms sign disappears.
Effective: clinical symptoms is clearly better or takes a turn for the better.
Invalid: clinical symptoms sign is without improvement.
(3) therapeutic effect: how to take effect at 15 days after taking medicine, cure 3-6 the course for the treatment of, and clinical 60 examples, cure 40 examples, account for 66%; Effective 12 examples, account for 20%; Effective 5 examples, account for 8.3%; Invalid 3 examples, account for 5%; Total effective rate 95%.
Embodiment 5:
Model case: often certain, 32 years old, female, patient's pale complexion, dizzy insomnia; depending on blurred vision flower, spiritlessness and weakness, over nearly 1 year, cardiopalmus after activity often, suffers from iron deficiency anemia, oral embodiment 1 Chinese medicine oral liquid; every day 3 times, 15ml/ time, to take medicine and take effect for latter 20 days, cure 3 courses for the treatment of.
Embodiment 6:
Model case: Zhu, 58 years old, female, suffered from pale complexion, spiritlessness and weakness, dizziness, depending on blurred vision flower, dreaminess and sleep night disintoxicated, loss of appetite, oral embodiment 1 Chinese medicine oral liquid, every day 3 times, 15ml/ time, takes medicine and takes effect for latter 20 days, 4 healings courses for the treatment of.
Claims (1)
1. a preparation method of alleviating the Chinese medicine oral liquid of iron deficiency anemia, is characterized in that: comprise the following steps:
A, get 300 parts of Caulis Spatholobis, 300 parts of Radix Polygoni Multiflori, 150 parts of Rhizoma Atractylodis, water decocts secondary, and each water consumption is 10 times of amounts of medical material weight, decocts secondary, each 1-2 hour, filters, and filtrate is condensed at 60 ℃ and surveys the clear paste that relative density is 1.10-1.25, adding ethanol is 60% to making containing amount of alcohol, stirs evenly, standing, filter, get filtrate recycling ethanol, be condensed into the extractum containing solid weight 65-67%, obtain extractum A;
B, get 150 parts of 150 parts of Radix Ginsengs, 150 parts of Radix Salviae Miltiorrhizaes, Ganoderma and be ground into 15 orders, each water consumption is 5 times of amounts of medical material weight, decocts secondary, each 1-2 hour, filter, filtrate is condensed at 60 ℃ and surveys the clear paste that relative density is 1.10-1.25, and adding ethanol is 60% to making containing amount of alcohol, stir evenly, standing, filter, get filtrate recycling ethanol, be condensed into the extractum containing solid weight 65-67%, obtain extractum B;
C, described extractum A and described extractum B are according to volume ratio 1:1, and merging mixes, and adds sucrose 20%, refined honey 12%, antiseptic 1-3%, stock solution embedding, and irradiation sterilization, packed products, makes oral liquid, obtains.
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| CN101147791A (en) * | 2007-09-05 | 2008-03-26 | 麦过渡 | Traditional Chinese medicine preparation for enriching blood and its preparation method |
| CN101322778A (en) * | 2008-07-22 | 2008-12-17 | 北京康比特体育科技股份有限公司 | Double-layer sustained release tablets for compensating iron and preparation thereof |
| CN102379986A (en) * | 2011-10-11 | 2012-03-21 | 邓华伦 | Chinese herbal medicament for treating Yin-Yang vital energy-blood deficiency and collapse |
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| KR101153436B1 (en) * | 2010-03-24 | 2012-06-05 | 경희대학교 산학협력단 | Composition of herb medicine containing kmkkt extract for preventing or treating cytopenia |
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| CN101147791A (en) * | 2007-09-05 | 2008-03-26 | 麦过渡 | Traditional Chinese medicine preparation for enriching blood and its preparation method |
| CN101322778A (en) * | 2008-07-22 | 2008-12-17 | 北京康比特体育科技股份有限公司 | Double-layer sustained release tablets for compensating iron and preparation thereof |
| CN102379986A (en) * | 2011-10-11 | 2012-03-21 | 邓华伦 | Chinese herbal medicament for treating Yin-Yang vital energy-blood deficiency and collapse |
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