CN102669003A - Resistance training and hindlimb muscular strength testing device for rats - Google Patents

Abstract

The invention belongs to the technical field of animal experiments, in particular to a rat physiological experiment device. A rat resistance exercise and hindlimb muscle strength testing device is characterized in that: it comprises: resistance exercise device, light stimulator (7), electric stimulator (16), controller (15), measuring and recording device ( 17). The present invention enables the rats to establish light and electricity reflections through the combination of light stimulation and electrical stimulation, so that the rats can lift a certain weight, and achieve the purpose of exercise or testing by changing the load weight, and can also evaluate the strength of the hind limbs of the rats. And the operation of the experiment process is simple and convenient.

Description

Rat Resistance Exercise and Hind Limb Muscle Strength Testing Device

technical field

The invention belongs to the technical field of animal experiments, in particular to a rat physiological experiment device.

Background technique

The research on the use of rats for running exercise is very mature, but the research on the use of rats for resistance exercise is greatly limited due to the lack of corresponding resistance exercise models. In aerospace medicine, resistance exercise is an important protective measure against muscle atrophy and bone loss caused by weightlessness. It can only be applied in space after sufficient resistance exercise on the ground. Therefore, it is urgent to establish a rat resistance exercise model for to conduct research. The rat hindlimb resistance training models reported in the literature at home and abroad mainly include: 1. Using food to induce rats to exercise, this method is difficult to increase the exercise load of rats; 2. Using electric arc to stimulate rats to exercise, this method mainly exercises flexor muscles ; 3. Using electricity or contact to stimulate rats to exercise, the method is cumbersome to operate. At present, the evaluation of rat muscle strength only has a test method for the grip strength of rat forelimbs, and there is no test method for hindlimb strength.

Contents of the invention

The purpose of the present invention is to provide a simple and convenient device which can carry out resistance exercise and hindlimb strength test of rats.

The technical scheme of the present invention is: a rat resistance exercise and hindlimb muscle strength testing device, which includes: resistance exercise device, light stimulator, electric stimulator, controller, measurement and recording device;

The resistance exercise device includes: a base with a conductive layer on the upper surface; a cylindrical experimental cabin that is vertically placed in the middle of the base and adopts transparent and insulating materials for accommodating rats; The gap at the tail of the rat; the inner cylinder coaxially arranged in the experimental cabin, which can be pushed up by the upper limbs of the rat and falls back freely, and its top is provided with a hole for the head of the rat to protrude; The axial position of the inner cylinder is adapted to the adjustment device of the rat's body length; the load with adjustable weight is applied to the inner cylinder; the feeler rod that moves up and down along with the inner cylinder; the travel switch triggered by the feeler rod , when the touch rod rises to a predetermined height, the travel switch sends a signal for the rat to complete the weightlifting action; it is arranged at the bottom of the experimental cabin to feel the pressure sensor of the rat's hind limb pedaling and stretching force;

The light stimulator is controlled by the controller and sends a light stimulation signal to the rat;

The electrical stimulator is controlled by the controller, and sends an electrical stimulation signal to the rat through two electrodes respectively connected to the conductive layer on the upper surface of the base and the tail of the rat;

The controller stores the experimental program, and controls the light stimulator and the electrical stimulator to work in time sequence;

The measuring and recording device receives and records the signal sent by the travel switch that the rat completes the weightlifting action, and the signal of the rat's rear leg kicking and stretching force output by the pressure sensor.

The present invention combines light stimulation and electric stimulation to make rats establish reflections on light and electricity, so that rats can lift a certain weight, and achieve the purpose of exercise or testing by changing the load weight, and can also evaluate the strength of rat hind limbs. And the operation of the experiment process is simple and convenient.

Description of drawings

Fig. 1 is a sectional view of the present invention;

Fig. 2 is a schematic diagram of a three-dimensional structure of the present invention;

Fig. 3 is a block diagram of signal transmission relationship in the present invention.

Detailed ways

Embodiment 1: referring to each accompanying drawing, a kind of rat resistance exercise and hindlimb muscle strength testing device is characterized in that: it comprises: resistance exercise device, light stimulator 7, electrical stimulator 16, controller 15, measure Recording device 17;

The resistance exercise device comprises: a base 1 whose upper surface is a conductive layer; standing in the middle of the base 1, adopting transparent and insulating materials, a cylindrical experimental cabin 2 for accommodating rats; There is a notch 9 leading out the tail of the rat; an inner tube 4 coaxial with the experimental cabin 2 is arranged, the inner tube 4 can be pushed up by the upper limbs of the rat and falls back freely, and the top is provided with a rat head. A hole 11 protruding from the top; adjusting the axial position of the inner cylinder 4 to adapt to the adjustment device 8 of the rat's body length; applying a load 6 with adjustable weight on the inner cylinder 4; moving up and down with the inner cylinder 4 The contact rod 5; the travel switch 3 triggered by the contact rod 5, when the contact rod 5 rises to a predetermined height, the travel switch 3 sends a signal that the rat completes the weightlifting action; it is arranged in the experimental cabin 2 At the bottom, a pressure sensor 10 for feeling the rat's hind limb kicking and stretching force;

The optical stimulator 7 is controlled by the controller 15, and sends a light stimulation signal to the rat;

The electrical stimulator 16 is controlled by the controller 15, and sends an electrical stimulation signal to the rat through two electrodes respectively connected to the conductive layer on the upper surface of the base 1 and the tail of the rat;

The controller 15 stores the experimental program, controls the optical stimulator 7 and the electrical stimulator 16 to work in time sequence;

The measurement and recording device 17 receives and records the signal from the travel switch 3 that the rat completes the weightlifting action, and the signal from the pressure sensor 10 on the rat's hind limb stretching force.

Embodiment 2: the rat resistance exercise and hindlimb muscle strength testing device as described in embodiment 1, is characterized in that: described controller 15 simultaneously controls multiple sets of described light stimulator 7, described electric stimulator 16, to perform multiple experiments simultaneously.

Claims (2)

1. A rat resistance exercise and hindlimb muscle strength testing device is characterized in that: it comprises: resistance exercise device, light stimulator (7), electric stimulator (16), controller (15), measurement record device (17); The resistance exercise device comprises: a base (1) whose upper surface is a conductive layer; a cylindrical experimental cabin ( 2), its lower part is provided with the breach (9) that draws out the rat tail; The inner tube (4) that is arranged in the described experimental cabin (2) and is coaxial with it, described inner tube (4) can be used by rat upper limb Push up and fall back freely, and its top is provided with the hole (11) that rat head stretches out; Regulate described inner cylinder (4) axial position to adapt to the regulating device (8) of rat body length; The load (6) with adjustable weight on the inner cylinder (4); the feeler rod (5) that moves up and down along with the inner cylinder (4); the travel switch (3) triggered by the feeler rod (5), when When the touch rod (5) rises to a predetermined height, the travel switch (3) sends a signal that the rat completes the weightlifting action; it is arranged at the bottom of the experimental cabin (2) to feel the pressure sensor of the rat's hind limb stretching force (10); The light stimulator (7) is controlled by the controller (15), and sends a light stimulation signal to the rat; The electrical stimulator (16) is controlled by the controller (15), and sends an electrical stimulation signal to the rat through two electrodes respectively connected to the conductive layer on the upper surface of the base (1) and the tail of the rat; The controller (15) stores the experimental program, controls the optical stimulator (7) and the electrical stimulator (16) to work in time sequence; The measurement and recording device (17) receives and records the signal from the travel switch (3) that the rat completes the weightlifting action, and the signal from the pressure sensor (10) on the force of the rat's hind limb stretching. 2. rat resistance exercise according to claim 1 and hindlimb muscle strength testing device are characterized in that: said controller (15) simultaneously controls multiple sets of said light stimulator (7), said electric stimulator (16), to perform multiple experiments simultaneously.

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