CN102631234A - Deep cerebral dura mater perforating device - Google Patents
Deep cerebral dura mater perforating device Download PDFInfo
- Publication number
- CN102631234A CN102631234A CN2012101028113A CN201210102811A CN102631234A CN 102631234 A CN102631234 A CN 102631234A CN 2012101028113 A CN2012101028113 A CN 2012101028113A CN 201210102811 A CN201210102811 A CN 201210102811A CN 102631234 A CN102631234 A CN 102631234A
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- Prior art keywords
- probe
- conduit
- pecker
- dura mater
- spacing head
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
- 230000002490 cerebral effect Effects 0.000 title claims description 29
- 210000001951 dura mater Anatomy 0.000 title claims description 25
- 239000000523 sample Substances 0.000 claims abstract description 28
- 238000004080 punching Methods 0.000 claims description 7
- 210000002418 meninge Anatomy 0.000 abstract description 10
- 230000006378 damage Effects 0.000 abstract description 7
- 210000004556 brain Anatomy 0.000 abstract description 6
- 210000005013 brain tissue Anatomy 0.000 abstract description 4
- 238000003780 insertion Methods 0.000 abstract description 4
- 230000037431 insertion Effects 0.000 abstract description 4
- 210000001519 tissue Anatomy 0.000 description 4
- 229910000831 Steel Inorganic materials 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 238000001690 micro-dialysis Methods 0.000 description 3
- 238000005070 sampling Methods 0.000 description 3
- 210000003625 skull Anatomy 0.000 description 3
- 239000010959 steel Substances 0.000 description 3
- 241000282553 Macaca Species 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- 210000003552 inferior colliculi Anatomy 0.000 description 2
- 210000003863 superior colliculi Anatomy 0.000 description 2
- 208000037816 tissue injury Diseases 0.000 description 2
- 229910001069 Ti alloy Inorganic materials 0.000 description 1
- 238000005452 bending Methods 0.000 description 1
- 210000000133 brain stem Anatomy 0.000 description 1
- 239000004568 cement Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000005457 optimization Methods 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
Images
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- Absorbent Articles And Supports Therefor (AREA)
- Surgical Instruments (AREA)
Abstract
本发明属生命科学用的装置。包括有一导管，一探针、一穿孔针、两根或两根以上的扩孔针。探针、穿孔针和扩孔针均带限位头。导管起引导作用，用于引导穿孔针和扩孔针插入脑内预定位置。探针尖端为钝圆形，既可用于导管插入脑内时堵塞导管，以减少对导管通过路径上的脑组织的损伤，又可用于探测脑膜的存在和位置。穿孔针尖端所带的锐利刃口最长，用于刺穿脑膜；第一根扩孔针尖端带比穿孔针刃口短一些的锐利刃口，第二根扩孔针尖端带更短一些的锐利刃口，依此类推，各扩孔针用于扩大穿孔针刺穿的脑膜孔洞。限位头能控制插入深度。本装置不仅可以快速穿透深部脑膜，而且对脑膜下脑组织的损伤极小，此外操作简单，体积小，重量轻。
The invention belongs to a device used in life sciences. It includes a catheter, a probe, a puncture needle, and two or more reaming needles. Probes, piercers and reamers all have stoppers. The catheter acts as a guide for guiding the perforation needle and the reaming needle into the predetermined position in the brain. The tip of the probe is blunt and round, which can be used to block the catheter when the catheter is inserted into the brain, so as to reduce the damage to the brain tissue along the passage of the catheter, and can also be used to detect the existence and position of the meninges. The tip of the reamer has the longest sharp edge and is used to pierce the meninges; the first reamer tip has a shorter sharp edge and the second reamer tip has a shorter The sharp edge, and so on, each reamer is used to widen the meningeal hole that the piercer pierced. The limit head can control the insertion depth. The device can not only quickly penetrate the deep meninges, but also cause minimal damage to the brain tissue under the meninges. In addition, the device is simple to operate, small in size and light in weight.
Description
Affiliated technical field
The invention belongs to the life sciences technical field, be specifically related to a kind of device that is used for the animal or human is carried out deep cerebral dura mater perforation.
Background technology
The animal and human is at the very strong cerebral dura mater of the surface coverage flexible at positions such as brain stem.Deep cerebral dura mater perforation is the problem that zoology at first need solve when the function in research brain district, deep (like superior colliculus, inferior colliculus and XIAONAO).In biological study; Adopt these brain districts of unit discharge technical notes movable or when sampling with the microdialysis method; Because recording electrode is more elongated very low with the most advanced and sophisticated dialyzer intensity of microdialysis sampling probe; Bending can take place when running into cerebral dura mater and stop or damage, therefore before inserting recording electrode and microdialysis sampling probe, at first need cerebral dura mater be pierced through pore-creating.Be to adopt conventional puncture needle to pierce through cerebral dura mater at present, be difficult to reasons such as grasp owing to insertion depth, can cause bigger damage to cerebral tissue under the cerebral dura mater inevitably, cause the cell of damage location can't write down research.
Summary of the invention
The objective of the invention is to overcome the shortcoming of prior art; A kind of deep cerebral dura mater punching machine is provided; Realization can be pierced through cerebral dura mater, can perhaps can farthest not reduce the damage that perforation procedure causes cerebral tissue under the cerebral dura mater because of perforation procedure causes damage to cerebral tissue under the cerebral dura mater again.
The structure of apparatus of the present invention is:
Include a conduit, and can insert in the conduit and pasting the following assembly that the pipe inner wall periphery slides: probe, pecker, the reaming pin more than two or two;
The probe tip end is that spherical crown shape or ellipsoid are crown, and the needle end of pecker and each reaming pin is the triangular or four rib shapes of band cutting edge;
The sharpness of pecker needle end and cutting edge length are maximum, and the sharpness and the cutting edge length of each reaming pin needle end reduce successively;
One end of probe, pecker and each reaming pin is all with the spacing head that can not get in the conduit;
The part that probe, pecker and each reaming pin probe do not contain spacing head is all long than conduit.
The material of apparatus of the present invention can be to make high-strength stainless steel that medical apparatus and instruments uses, titanium alloy etc.; Spacing head can be for cylindric, and prism-shaped is rectangular-shaped etc.
The architectural feature of apparatus of the present invention optimization is:
Pecker is the triangular shape of band cutting edge with each reaming pin needle end.
The part that probe does not contain spacing head is longer 1～1.5 millimeter than conduit.
The part that pecker does not contain spacing head is longer 1.1～1.5 millimeters than conduit, long 2～5 millimeters of cutting edge.
The part that each reaming pin does not contain spacing head is longer 1.1～1.5 millimeters than conduit.
The structure that apparatus of the present invention are further optimized is: the reaming pin is two, and spacing head is cylindric.
The operation principle of apparatus of the present invention: conduit plays guiding function, is used for PP pilot punch pin and reaming pin and inserts precalculated position in the brain.Probe tip is a blunt round, both can be used for stopping up conduit when conduit inserts in the brain, to reduce conduit is passed through the brain tissue injury on the path, can be used for surveying the existence and the position of meninges again.Pecker most advanced and sophisticated with sharp keen cutting edge the longest, be used to pierce through meninges; First reaming needle tip band be than the shorter sharp keen cutting edge of pecker cutting edge, second sharp keen cutting edge that reaming needle tip band is shorter, and the rest may be inferred, and each reaming pin is used to enlarge the meninges hole that pecker pierces through.Probe, pecker and each reaming with spacing head can control insertion depth.
The use of apparatus of the present invention: at first, drill through skull, the conduit that is inserted with probe is advanced into catheter proximal end through the skull hole arrives the cerebral dura mater upper surface in the boring of skull anchor point.When the probe in the conduit touched cerebral dura mater, probe can be by cerebral dura mater jack-up, and this moment is with medical dens supporter cement A/C.After treating the conduit fixation; Probe is extracted, then in conduit, inserted that the longest root pecker of cutting edge, when treating the pecker tip near cerebral dura mater; With spring hammer hammering pecker with the afterbody of spacing head, the pecker tip just penetrates cerebral dura mater rapidly and the deformation of cerebral tissue depression does not take place.Then this pecker is extracted; Order by needle end sharpness and the reduction of cutting edge length; Successively each reaming pin is inserted and extracts conduit, reaming pin of every insertion just with this reaming pin of spring hammer hammering with spacing afterbody, to enlarge the cerebral dura mater hole one by one.
The advantage of apparatus of the present invention: not only can quick penetration deep meninges, and also minimum to brain tissue injury under the meninges, simple to operate in addition, volume is little, and is in light weight.
Description of drawings
Fig. 1 looks cross-sectional view for the master of conduit among the embodiment.
Fig. 2 is the main TV structure sketch map of embodiment middle probe.
Fig. 3 is the main TV structure sketch map of embodiment middle punch pin.
Fig. 4 is the main TV structure sketch map of the first reaming pin among the embodiment.
Fig. 5 is the main TV structure sketch map of the second reaming pin among the embodiment.
The specific embodiment
Embodiment 1: see Fig. 1～5.This product is used for the hard meninges in macaque superior colliculus surface of the degree of depth＞25mm is punctured, and result of use is fine.
The reaming pin is two.Conduit 1 is processed by rustless steel.Probe 2, pecker 3, the first reaming pin 4 and the second reaming pin 5 are also processed by rustless steel, and their needle end is the triangular shape of band cutting edge, and their other end all is with the spacing head of cylindrical shape.
The length of conduit 1 is 31 millimeters, and internal diameter is 0.59 millimeter.The length that probe 2 does not contain spacing head part is 32.5 millimeters, and 6 is its spacing head.The length that pecker 3 does not contain spacing head part is 32.5 millimeters, long 3.5 millimeters of cutting edge, and 7 is its spacing head.The length that the first reaming pin 4 does not contain spacing head part is 32.2 millimeters, long 0.5 millimeter of cutting edge, and 8 is its spacing head.The length that the second reaming pin 5 does not contain spacing head part is 32.2 millimeters, long 0.3 millimeter of cutting edge, and 9 is its spacing head.
Embodiment 2: this product is processed by rustless steel, is used for the cerebral dura mater on macaque inferior colliculus surface is bored a hole, and result of use is fine.
The reaming pin is two.The needle end of conduit, probe, puncture needle, the first reaming pin and the second reaming pin is the triangular shape of band cutting edge, and their other end all is with rectangular-shaped spacing head.
The length of conduit is 34 millimeters, and internal diameter is 0.59 millimeter.The length that probe does not contain spacing head part is 35.5 millimeters, and the length that pecker does not contain spacing head part is 35.5 millimeters, the long 3-3.5 millimeter of cutting edge.The length that the first reaming pin does not contain spacing head part is 35.2 millimeters, long 0.5 millimeter of cutting edge.The length that the second reaming pin does not contain spacing head part is 35.2 millimeters, long 0.3 millimeter of cutting edge.
Above embodiment only is for the present invention is described further, and scope of the present invention does not receive the limitation of the embodiment that lifts.
Claims (5)
1. deep cerebral dura mater punching machine is characterized in that: include a conduit, and can insert in the conduit and pasting the following assembly that the pipe inner wall periphery slides: probe, pecker, the reaming pin more than two or two;
The probe tip end is that spherical crown shape or ellipsoid are crown, and the needle end of pecker and each reaming pin is the triangular or four rib shapes of band cutting edge;
The sharpness of pecker needle end and cutting edge length are maximum, and the sharpness and the cutting edge length of each reaming pin needle end reduce successively;
One end of probe, pecker and each reaming pin is all with the spacing head that can not get in the conduit;
The part that probe, pecker and each reaming pin probe do not contain spacing head is all long than conduit.
2. like the said deep of claim 1 cerebral dura mater punching machine, it is characterized in that: pecker is the triangular shape of band cutting edge with each reaming pin needle end.
3. like the said deep of claim 1 cerebral dura mater punching machine, it is characterized in that: the part that probe does not contain spacing head is longer 1～1.5 millimeter than conduit; The part that pecker does not contain spacing head is longer 1.1～1.5 millimeters than conduit, long 2～5 millimeters of cutting edge; The part that each reaming pin does not contain spacing head is longer 1.1～1.5 millimeters than conduit.
4. like the said deep of claim 2 cerebral dura mater punching machine, it is characterized in that the reaming pin is two
5. like the said deep of claim 2 cerebral dura mater punching machine, it is characterized in that spacing head is for cylindric.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210102811.3A CN102631234B (en) | 2012-04-10 | 2012-04-10 | Deep cerebral dura mater perforating device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210102811.3A CN102631234B (en) | 2012-04-10 | 2012-04-10 | Deep cerebral dura mater perforating device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102631234A true CN102631234A (en) | 2012-08-15 |
| CN102631234B CN102631234B (en) | 2014-01-22 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210102811.3A Expired - Fee Related CN102631234B (en) | 2012-04-10 | 2012-04-10 | Deep cerebral dura mater perforating device |
Country Status (1)
| Country | Link |
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| CN (1) | CN102631234B (en) |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103284980A (en) * | 2013-06-18 | 2013-09-11 | 中国科学院昆明动物研究所 | Method for establishing animal model for senile dementia, special liquid medicine and dosing device |
| CN103340859A (en) * | 2013-06-04 | 2013-10-09 | 中国科学院昆明动物研究所 | Method for establishing non-human primate animal model of Parkinson's disease by administration of MPP+ in lateral ventricle |
| CN104783919A (en) * | 2015-04-29 | 2015-07-22 | 桂林医学院 | Brain tissue damage experimental facility |
| CN105286954A (en) * | 2014-06-07 | 2016-02-03 | 王苏 | Closed chest drainage puncture outfit and application thereof |
| CN108926384A (en) * | 2018-07-06 | 2018-12-04 | 北京柏惠维康科技有限公司 | Meninx needle and meninx hole-drilling system |
| CN110064104A (en) * | 2018-01-22 | 2019-07-30 | 南京农业大学 | A kind of surface has the medical use needle and preparation method thereof of micro-nano composite antibacterial texture |
| CN114469280A (en) * | 2022-01-24 | 2022-05-13 | 上海精劢医疗科技有限公司 | Sensing positioning needle |
| CN119411205A (en) * | 2025-01-02 | 2025-02-11 | 临港国家实验室 | Needle preparation method and needle |
| CN119837612A (en) * | 2025-03-19 | 2025-04-18 | 中国科学院脑科学与智能技术卓越创新中心 | Implant assembly and corresponding implant device |
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| CN201930380U (en) * | 2010-12-10 | 2011-08-17 | 谷卫民 | Skull puncture drainage nail |
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2012
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| CN86200383U (en) * | 1986-01-23 | 1986-12-24 | 江砥宸 | Combined hole-drilling and dilatating drill for opening skull |
| US4721506A (en) * | 1986-11-07 | 1988-01-26 | Teves Leonides Y | Flat-inclined tip needle |
| EP0401525A1 (en) * | 1989-06-06 | 1990-12-12 | B. Braun Melsungen AG | Set of instruments with a catheter for continuous spinal anaesthesia |
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Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103340859A (en) * | 2013-06-04 | 2013-10-09 | 中国科学院昆明动物研究所 | Method for establishing non-human primate animal model of Parkinson's disease by administration of MPP+ in lateral ventricle |
| CN103284980A (en) * | 2013-06-18 | 2013-09-11 | 中国科学院昆明动物研究所 | Method for establishing animal model for senile dementia, special liquid medicine and dosing device |
| CN105286954A (en) * | 2014-06-07 | 2016-02-03 | 王苏 | Closed chest drainage puncture outfit and application thereof |
| CN104783919A (en) * | 2015-04-29 | 2015-07-22 | 桂林医学院 | Brain tissue damage experimental facility |
| CN110064104A (en) * | 2018-01-22 | 2019-07-30 | 南京农业大学 | A kind of surface has the medical use needle and preparation method thereof of micro-nano composite antibacterial texture |
| CN108926384A (en) * | 2018-07-06 | 2018-12-04 | 北京柏惠维康科技有限公司 | Meninx needle and meninx hole-drilling system |
| CN114469280A (en) * | 2022-01-24 | 2022-05-13 | 上海精劢医疗科技有限公司 | Sensing positioning needle |
| CN119411205A (en) * | 2025-01-02 | 2025-02-11 | 临港国家实验室 | Needle preparation method and needle |
| CN119411205B (en) * | 2025-01-02 | 2025-06-10 | 临港国家实验室 | Needle preparation method and needle |
| CN119837612A (en) * | 2025-03-19 | 2025-04-18 | 中国科学院脑科学与智能技术卓越创新中心 | Implant assembly and corresponding implant device |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102631234B (en) | 2014-01-22 |
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Owner name: ZHEJIANG UNIVERSITY Effective date: 20150427 |
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Inventor after: Lei Xiaoguang Inventor after: Yang Shangchuan Inventor after: Wu Jing Inventor after: Wang Wenchao Inventor after: Hu Yingzhou Inventor after: Ma Yuanye Inventor after: Hu Xintian Inventor after: Zhang Baorong Inventor before: Yang Shangchuan Inventor before: Wu Jing Inventor before: Hu Yingzhou Inventor before: Ma Yuanye Inventor before: Hu Xintian |
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Free format text: CORRECT: INVENTOR; FROM: YANG SHANGCHUAN WU JING HU YINGZHOU MA YUANYE HU XINTIAN TO: LEI XIAOGUANGYANG SHANGCHUAN WU JING WANG WENCHAO HU YINGZHOU MA YUANYE HU XINTIAN ZHANG BAORONG |
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Effective date of registration: 20150427 Address after: 650000 No. 32 East Road, Kunming, Yunnan Patentee after: Kuiming Animal Institute of Chinese Academy of Sciences Patentee after: Zhejiang University Address before: 650000 No. 32 East Road, Kunming, Yunnan Patentee before: Kuiming Animal Institute of Chinese Academy of Sciences |
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