CN102579836B - Traditional Chinese medical dendrobium huoshanense composition and preparation method thereof - Google Patents
Traditional Chinese medical dendrobium huoshanense composition and preparation method thereof Download PDFInfo
- Publication number
- CN102579836B CN102579836B CN2012100537328A CN201210053732A CN102579836B CN 102579836 B CN102579836 B CN 102579836B CN 2012100537328 A CN2012100537328 A CN 2012100537328A CN 201210053732 A CN201210053732 A CN 201210053732A CN 102579836 B CN102579836 B CN 102579836B
- Authority
- CN
- China
- Prior art keywords
- extract
- herba dendrobii
- traditional chinese
- preparation
- dendrobium huoshanense
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 241001678082 Dendrobium huoshanense Species 0.000 title claims abstract 6
- 239000000203 mixture Substances 0.000 title claims abstract 5
- 238000002360 preparation method Methods 0.000 title claims abstract 3
- 239000003814 drug Substances 0.000 claims abstract 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract 3
- 239000000284 extract Substances 0.000 claims 9
- 229940079593 drug Drugs 0.000 claims 4
- 238000001914 filtration Methods 0.000 claims 3
- 239000007788 liquid Substances 0.000 claims 3
- 238000010298 pulverizing process Methods 0.000 claims 3
- 238000010992 reflux Methods 0.000 claims 3
- 238000001291 vacuum drying Methods 0.000 claims 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 2
- 239000009636 Huang Qi Substances 0.000 claims 2
- 238000007796 conventional method Methods 0.000 claims 1
- 238000009472 formulation Methods 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
- 238000003756 stirring Methods 0.000 claims 1
- 238000005406 washing Methods 0.000 claims 1
- 241000045403 Astragalus propinquus Species 0.000 abstract 1
- 240000005373 Panax quinquefolius Species 0.000 abstract 1
- 235000003140 Panax quinquefolius Nutrition 0.000 abstract 1
- 235000006533 astragalus Nutrition 0.000 abstract 1
- 238000001035 drying Methods 0.000 abstract 1
- 238000002481 ethanol extraction Methods 0.000 abstract 1
- 235000008216 herbs Nutrition 0.000 abstract 1
- 238000003809 water extraction Methods 0.000 abstract 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a traditional Chinese medical dendrobium huoshanense composition and a preparation method thereof, wherein the traditional Chinese medical dendrobium huoshanense composition is prepared via water or ethanol extraction, concentration and drying of 25-35 percent of dendrobium huoshanense, 20-30 percent of astragalus mongholicus, 20-35 percent of folium cortex eucommiae and 20-30 percent of American ginseng by mass percentage. Based on the traditional Chinese medicine theory, the dendrobium huoshanense and other valuable Chinese herbs are scientifically and reasonably mixed, and the combination and formula are optimized to achieve the purpose of improving healthcare effects.
Description
One, technical field
The present invention relates to a kind of Chinese medicine health care product, specifically a kind of Traditional Chinese medical dendrobium huoshanense composition and preparation method thereof.
Two, background technology
Herba Dendrobii is the orchid family Dendrobium Sw, and China has 74 kinds and 2 mutation of the orchid family Dendrobium Sw now, and wherein 26 kinds have medicinal.Medicinal dendrobium has reinforcing stomach reg fluid, clearing away heat and nourishing YIN, and the multiple efficacies such as sore throat relieving makes eye bright, enhancing immunity and alleviating physical fatigue are wherein famous and precious with Herba Dendrobii, and medical value and health care are worth the highest.But due to extremely harshness and excessive the excavating of Herba Dendrobii habitat, its wild resource has been on the verge of disappearance.The applicant has realized artificial breeding and cultivation by the modern plants tissue culture technology, for the exploitation of Herba Dendrobii provide raw material.
The tradition Herba Dendrobii utilize mode single, be taken after being infused in hot water or decoction with boiled water mainly with single medical material greatly.But in Herba Dendrobii main composition---dendrobium polysaccharide viscosity is large, and dissolution rate is slow, and dissolution rate is low, therefore the utilization rate of its active ingredient is extremely low.Ignore simultaneously the theory of monarch in the Traditional Chinese Medicine, not with the other drug reasonable compatibility, therefore be difficult to reach health-care effect preferably.
The Herba Dendrobii class compound Chinese medicinal preparation of present domestic research and development and health food are raw material mainly with Herba Dendrobii greatly, and the compound Chinese medicinal preparation take Herba Dendrobii as raw material is less.Number of patent application is that two patents of invention of 201110198864.5 and 201110198866.4 disclose respectively " a kind of formula of compound dendrobium huoshanense extract and production technology " and " a kind of formula of compound dendrobium huoshanense granules and production method ".But have all that the product compatibility is relatively single, dosage form is carried and take inconvenience and the defective such as functional component content is lower.The formula of the Herba Dendrobii hard capsule that patent of the present invention relates to and be applied in domestic there are no bibliographical information.
Along with the continuous quickening of rhythm of life and the increasing of operating pressure, the physical fatigue symptom has in various degree performance with it nearly all adult." white collar " of most domestic just experiencing in various degree psychological fatigue, physical fatigue according to investigations, and further developing of this state will cause the organs function imbalance, the consume of vital essence blood.Therefore, the resisting fatigue problem has caused more and more people's attention, and the eating effect of fatigue resistant health food in the market is unsatisfactory, and formula is mainly take yang-tonifying drug as main, and portioned product also has certain toxic and side effects.Therefore how to make by scientific experiments the health food that has these effects and have no side effect, have the very meaning of Chinese medicine.
Three, summary of the invention
The present invention aims to provide a kind of Traditional Chinese medical dendrobium huoshanense composition and preparation method thereof, and the technical solution problem of is to find suitable compatibility composition to improve the utilization rate of Herba Dendrobii active ingredient.
In order to give full play to Herba Dendrobii to the mankind's health-care effect, open up its application prospect in health food and medicine, the present invention is take theory of Chinese medical science as the basis, with Herba Dendrobii and Radix Panacis Quinquefolii, Folium Eucommiae and Radix Astragali compatibility, maximally utilise the functional component of Herba Dendrobii, also helped storage, transportation.
Technical solution problem of the present invention adopts following technical scheme:
Traditional Chinese medical dendrobium huoshanense composition of the present invention, be with the prepared slices of Chinese crude drugs of following mass percent through water or ethanol extraction and the Chinese medicine composition through concentrating, obtaining after drying:
Herba Dendrobii 25-35%, Radix Astragali 20-30%, Folium Eucommiae 20-35%, Radix Panacis Quinquefolii 20-30%.
The preparation method of Traditional Chinese medical dendrobium huoshanense composition of the present invention is to operate according to the following steps:
Take Herba Dendrobii, the Radix Astragali, Folium Eucommiae and the Radix Panacis Quinquefolii prepared slices of Chinese crude drugs by proportional quantity, washing is also dry;
The Herba Dendrobii prepared slices of Chinese crude drugs were pulverized the 10-20 mesh sieve, added the water of 10-20 times of weight, reflux, extract, three times, each 3-8 hour, merge three times extracting solution, extracting liquid filtering and vacuum concentration be to the thick paste shape, then obtain the Herba Dendrobii extract through vacuum drying, after pulverizing;
The Radix Panacis Quinquefolii prepared slices of Chinese crude drugs were pulverized the 10-20 mesh sieve, the ethanol that adds the concentration expressed in percentage by volume 65-85% of 10-20 times of weight, reflux, extract, three times, each 2-4 hour, merge three times extracting solution, extracting liquid filtering and vacuum concentration be to the thick paste shape, then obtain Radix Panacis Quinquefolii extract through vacuum drying, after pulverizing;
The Radix Astragali and the Folium Eucommiae prepared slices of Chinese crude drugs are mixed, add the water of 8-15 times of weight, reflux, extract, three times, each 2-4 hour, merges three times extracting solution, extracting liquid filtering and vacuum concentration be to the thick paste shape, then obtain mixed extract after vacuum drying, pulverizing;
Herba Dendrobii extract, Radix Panacis Quinquefolii extract and mixed extract are mixed and stir, be prepared into according to a conventional method oral solid formulation after adding appropriate amount of auxiliary materials, as granule, tablet, pill, drop pill, hard capsule, solid dispersion, powder, fine granule, pellet, microcapsule, microspheres agent or other pharmaceutically acceptable oral solid formulations.
In compatibility of the present invention:
The main active dendrobium polysaccharide of Herba Dendrobii has reinforcing YIN-essence benefit essence, thick the intestines and stomach, never sufficient in mending, flat gastric qi, longue meat, Fructus Alpiniae Oxyphyllae be except shying, make light of one's life by commiting suicide the multiple medicinal efficacy such as prolong life;
Radix Panacis Quinquefolii can improve thinking and body mobility, not only can strengthen neural excitation, also can strengthen its process of inhibition, make and suppress to be tending towards concentrated, thereby differentiation makes excited fully and suppresses two kinds of nervous process and is able to balance, improve people's intelligence and the work effect of muscle power, produce too much free radical when Radix Panacis Quinquefolii can be removed human body strenuous exercise simultaneously, accelerate the elimination effect to fatigue; The ginsenoside of containing in Radix Panacis Quinquefolii simultaneously promotes to organize the utilization to sugar, thereby promotes body to the absorption of dendrobium polysaccharide;
The contained chemical composition of Folium Eucommiae is mainly lignanoids, iridoids, Phenylpropanoid Glycosides class, flavonoid, aminoacid and trace element and polysaccharide etc., has invigorating the liver and kidney, the pharmacological action of bone and muscle strengthening; Studies show that simultaneously Folium Eucommiae have strengthen Tolerance of Swimming, reduce mouse movement after the blood lactate level remarkable effect is arranged, to as the blood urea nitrogen content of estimating the muscle injury index, reduction trend being arranged.Thereby have antifatigue effect, and do not contain analeptic and the hormone of International Olympic Committee's regulation forbidding.Thereby illustrate that Folium Eucommiae is that a kind of energy is used for the both economic of alleviating physical fatigue efficiency health-care food, the significant new raw material of effect again.
The Radix Astragali has the multiple efficacies such as invigorating QI to consolidate the body surface resistance, diuresis detoxification, evacuation of pus, expelling pus and promoting granulation, enhancing immunity and alleviating physical fatigue.
In the side, Herba Dendrobii is cool in nature, enriching yin and nourishing kidney, and reinforcing stomach reg fluid is mended gas among the taste day after tomorrow simultaneously, with the source of the angry blood of enhancingization, is monarch drug, the little suffering of Folium Eucommiae, temperature is good at the tonifying YANG of temperature compensation Liver and kidney, bone and muscle strengthening; Radix Astragali sweet in the mouth, tepor enter lung, spleen, dare, kidney channel, are longer than benefiting QI for strengthening the superficies, arresting sweating takes off, holds in the palm skin ulcer granulation promoting, inducing diuresis to remove edema admittedly, and two flavors are the in love product of flesh and blood, can high nourishing YIN sun with angry hemospermia marrow, be ministerial drug.Share with the most delicious, again with the boosting qi and nourishing yin of Radix Panacis Quinquefolii, the stack of clearing away heat and promoting production of body fluid effect science, have synergism preferably, can improve significantly the bioavailability of compatibe drug and effective ingredient, comprehensively strengthen its health care, all medicines are played altogether, the merit that invigorating both QI and YIN, QI and blood are taken into account, thus reach effect of relieving physical fatigue.
Compared with prior art, the invention has the advantages that:
1, the present invention is take theory of Chinese medical science as the basis, science with Herba Dendrobii and other rare Chinese medicine reasonable compatibility, optimum organization prescription, thus reach the purpose of enhancing health-care effect.
2, product of the present invention is easy to carry, absorb rapidly, and be a kind of modern preparation type that has than high technology content;
3, the present invention has realized the rational exploitation and utilization to this Valuable Herbal Medicine in imminent danger of Herba Dendrobii.
Four, the specific embodiment
The invention will be further described below in conjunction with embodiment, can be implemented so that those skilled in the art can better understand the present invention also, but illustrated embodiment is not as limiting to the invention.
Embodiment 1:
1, component: the raw material of Chinese medicine composition constitutes by mass percentage: Herba Dendrobii 30%, the Radix Astragali 25%, Folium Eucommiae 25%, Radix Panacis Quinquefolii 20%.
2, preparation method:
A, take Herba Dendrobii, the Radix Astragali, Folium Eucommiae and Radix Panacis Quinquefolii by proportional quantity, washing is also dry;
B, Herba Dendrobii is pulverized the 10-20 mesh sieve, added the water of 20 times of weight, reflux, extract, three times, each 6 hours, merge three times extracting solution, extracting solution filter with filter press and vacuum concentration to the thick paste shape, then obtain the Herba Dendrobii extract through vacuum drying, after pulverizing;
C, Radix Panacis Quinquefolii is pulverized the 10-20 mesh sieve, added the ethanol of the concentration expressed in percentage by volume 80% of 10 times of weight, reflux, extract, three times, each 3 hours, merge three times extracting solution, extracting liquid filtering and vacuum concentration be to the thick paste shape, then obtain Radix Panacis Quinquefolii extract through vacuum drying, after pulverizing;
D, the Radix Astragali and Folium Eucommiae are mixed, add the water of 8 times of weight, reflux, extract, three times, each 2 hours, merges three times extracting solution, extracting liquid filtering and vacuum concentration be to the thick paste shape, then obtain mixed extract after vacuum drying, pulverizing;
E, Herba Dendrobii extract, Radix Panacis Quinquefolii extract and mixed extract are mixed and stir and obtain the Traditional Chinese medical dendrobium huoshanense composition powder.
Embodiment 2: hard capsule
1, formula: the Traditional Chinese medical dendrobium huoshanense composition powder 65% of (by mass percentage) embodiment 1 preparation, microcrystalline Cellulose 35%.
2, preparation: with Traditional Chinese medical dendrobium huoshanense composition powder and the microcrystalline Cellulose mix homogeneously of embodiment 1 preparation, add the alcohol granulation of concentration expressed in percentage by volume 85% and cross 40 mesh sieves, incapsulating after 60 ℃ of dryings and get final product, the 0.25g/ grain.
3, instructions of taking: every day 2 times, each 4.
Embodiment 3:
1, component: the raw material of Chinese medicine composition constitutes by mass percentage: Herba Dendrobii 28%, the Radix Astragali 27%, Folium Eucommiae 22%, Radix Panacis Quinquefolii 23%.
2, preparation method:
A, take Herba Dendrobii, the Radix Astragali, Folium Eucommiae and Radix Panacis Quinquefolii by proportional quantity, washing is also dry;
B, Herba Dendrobii is pulverized the 10-20 mesh sieve, added the water of 15 times of weight, reflux, extract, three times, each 6 hours, merge three times extracting solution, extracting solution filter with filter press and vacuum concentration to the thick paste shape, then obtain the Herba Dendrobii extract through vacuum drying, after pulverizing;
C, Radix Panacis Quinquefolii is pulverized the 10-20 mesh sieve, added the ethanol of the concentration expressed in percentage by volume 85% of 13 times of weight, reflux, extract, three times, each 4 hours, merge 4 times extracting solution, extracting liquid filtering and vacuum concentration be to the thick paste shape, then obtain Radix Panacis Quinquefolii extract through vacuum drying, after pulverizing;
D, the Radix Astragali and Folium Eucommiae are mixed, add the water of 10 times of weight, reflux, extract, three times, each 2 hours, merges three times extracting solution, extracting liquid filtering and vacuum concentration be to the thick paste shape, then obtain mixed extract after vacuum drying, pulverizing;
E, Herba Dendrobii extract, Radix Panacis Quinquefolii extract and mixed extract are mixed and stir and obtain the Traditional Chinese medical dendrobium huoshanense composition powder.
Embodiment 4: hard capsule
1, formula: the Traditional Chinese medical dendrobium huoshanense composition powder 72% of (by mass percentage) embodiment 1 preparation, microcrystalline Cellulose 28%.
2, preparation: with Traditional Chinese medical dendrobium huoshanense composition powder and the microcrystalline Cellulose mix homogeneously of embodiment 1 preparation, add the alcohol granulation of concentration expressed in percentage by volume 90% and cross 40 mesh sieves, incapsulating after 60 ℃ of dryings and get final product, the 0.25g/ grain.
3, instructions of taking: every day 2 times, each 4.
Embodiment 5: granule
1, formula: the Traditional Chinese medical dendrobium huoshanense composition powder 62% of (by mass percentage) embodiment 1 preparation, dextrin 17%, maltodextrin 21%.
2, preparation: with Traditional Chinese medical dendrobium huoshanense composition powder and dextrin, the maltodextrin mix homogeneously of embodiment 1 preparation, add alcohol granulation and mistake 40 mesh sieves of concentration expressed in percentage by volume 90%, making content after 60 ℃ of dryings is tan granule, the 3g/ bag.
3, instructions of taking: one time 1 bag, 2 times on the one.
Embodiment 6: tablet
1, formula: the Traditional Chinese medical dendrobium huoshanense composition powder 66% of (by mass percentage) embodiment 1 preparation, lactose 13%, starch 18%, magnesium stearate 3%.
2, preparation: with Traditional Chinese medical dendrobium huoshanense composition powder and lactose, starch, the magnesium stearate mix homogeneously of embodiment 1 preparation, add alcohol granulation and mistake 20 mesh sieves of concentration expressed in percentage by volume 85%, 60 ℃ of dryings are pressed into tablet by tablet machine, the 0.6g/ sheet.
3, instructions of taking: one time 2,2 times on the one.
Embodiment 7: superfine powder
1, formula: the Traditional Chinese medical dendrobium huoshanense composition powder 90% of (by mass percentage) embodiment 1 preparation, maltodextrin 9.7%, sucralose 0.3%.
2, preparation: after the Traditional Chinese medical dendrobium huoshanense composition powder of embodiment 1 preparation and maltodextrin, sucralose mix homogeneously, be crushed to 2-6 ten thousand purpose superfine powder, in the vial of packing into, the 4g/ bottle.
3, instructions of taking: 2 grams, 2 times on the one.
[pharmacodynamic experiment]
The Traditional Chinese medical dendrobium huoshanense composition of the present invention's preparation entrusts sanitary analysis inspection center of Nanjing Medical University to carry out the animal experiment study of effect of relieving physical fatigue take hard capsule as test sample book.Recommend consumption according to the adult, establish the basic, normal, high dosage group of tested material, be respectively 0.17g/kg.bw, 0.34g/kg.bw, 1g/kg.bw (be equivalent to respectively human body recommended dose 5,10,30 times), establish simultaneously a negative control group.Adopt administration by gavage, every day, negative control group gave the distilled water of equivalent to mouse stomach various dose tested material, and every day, gavage was 1 time, connected 30d.31d carries out the mensuration of every resisting fatigue index.
1, swimming with a load attached to the body experiment: last to mice tested material 30min after, the sheet lead of Mus root of the tail section load 5% body weight is placed in the swimming trunk went swimming, the depth of water is 30cm approximately, 25 ℃ ± 0.5 ℃ of water temperature recorded mice and begins to Post-dead duration from swimming, as the mice burden swimming time.
2, serum urea is measured: last to mice tested material 30min after, temperature be 30 ℃ in not swimming with a load attached to the body 90min, pull out the centrifugal 15min of 2000r/min after the standing 3h of eyeball blood sampling after rest 60min, get serum with full Automatic Biochemical Analyzer mensuration serum urea.
3, hepatic glycogen is measured: last to mice tested material 30min after, put to death animal.Get liver and blot with filter paper after the normal saline rinsing, take liver 100mg, remaining operation is carried out hepatic glycogen by the test kit description and is measured.
4, blood Plasma lactate: last gives after tested material 30min from angular vein clump blood sampling 20uL, then do not bear a heavy burden and stop after temperature is the water went swimming 10min of 30 ℃, respectively at 0min and the same blood sampling of 20min 20uL after motion, measure blood lactic acid, calculate blood lactic acid area under curve.
The initial data of every experiment sees Table 1 and table 2.With SPSS software, each experiment initial data is carried out homogeneity test of variance, satisfy data information that " variance is neat " require and carry out statistical disposition with the comparative approach in twos of mean between one factor analysis of variance method and a plurality of experimental group and matched group.
Serum urea and hepatic glycogen measurement result after table 1 test sample is tested, moved mice burden swimming (x ± s)
Annotate: compare with negative control group,
*P＜0.05,
*＜0.01
Table 2 is respectively organized blood lactic acid (mg/L) area under curve after mouse movement (x ± s)
Annotate: compare with negative control group,
*P＜0.05,
*＜0.01
Data results shows, gavage is 30 days continuously, basic, normal, high dosage group all can extend the mice burden swimming time, the generation of serum urea when reducing mice swimming, the generation of blood lactic acid when reducing swimming, increase the hepatic glycogen deposit, wherein 1g/kg.bw dosage group and the matched group four indices that compares mice has difference extremely significantly.Judge thus, in this test dose scope, visible the present invention has the alleviating physical fatigue function.
Claims (1)
1. the preparation method of a Traditional Chinese medical dendrobium huoshanense composition is characterized in that operating according to the following steps:
Take the prepared slices of Chinese crude drugs of following mass percent by proportional quantity, washing is also dry: Herba Dendrobii 25-35%, Radix Astragali 20-30%, Folium Eucommiae 20-35%, Radix Panacis Quinquefolii 20-30%;
The Herba Dendrobii prepared slices of Chinese crude drugs were pulverized the 10-20 mesh sieve, added the water of 10-20 times of weight, reflux, extract, three times, each 3-8 hour, merge three times extracting solution, extracting liquid filtering and vacuum concentration be to the thick paste shape, then obtain the Herba Dendrobii extract through vacuum drying, after pulverizing;
The Radix Panacis Quinquefolii prepared slices of Chinese crude drugs were pulverized the 10-20 mesh sieve, the ethanol that adds the concentration expressed in percentage by volume 65-85% of 10-20 times of weight, reflux, extract, three times, each 2-4 hour, merge three times extracting solution, extracting liquid filtering and vacuum concentration be to the thick paste shape, then obtain Radix Panacis Quinquefolii extract through vacuum drying, after pulverizing;
The Radix Astragali and the Folium Eucommiae prepared slices of Chinese crude drugs are mixed, add the water of 8-15 times of weight, reflux, extract, three times, each 2-4 hour, merges three times extracting solution, extracting liquid filtering and vacuum concentration be to the thick paste shape, then obtain mixed extract after vacuum drying, pulverizing;
Herba Dendrobii extract, Radix Panacis Quinquefolii extract and mixed extract are mixed and stir, be prepared into according to a conventional method oral solid formulation after adding appropriate amount of auxiliary materials.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012100537328A CN102579836B (en) | 2012-03-02 | 2012-03-02 | Traditional Chinese medical dendrobium huoshanense composition and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012100537328A CN102579836B (en) | 2012-03-02 | 2012-03-02 | Traditional Chinese medical dendrobium huoshanense composition and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102579836A CN102579836A (en) | 2012-07-18 |
| CN102579836B true CN102579836B (en) | 2013-06-12 |
Family
ID=46469437
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2012100537328A Active CN102579836B (en) | 2012-03-02 | 2012-03-02 | Traditional Chinese medical dendrobium huoshanense composition and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102579836B (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105029394A (en) * | 2014-04-15 | 2015-11-11 | 四川万安石斛产业开发有限公司 | Anti-fatigue health-caring product or medicine composition |
| CN104509620A (en) * | 2014-12-11 | 2015-04-15 | 罗生芳 | Herbal tea containing eucommia folium and preparation method thereof |
| CN104705641B (en) * | 2014-12-11 | 2017-01-11 | 江苏古月楼餐饮有限公司 | Soup dumpling stuffing and manufacturing method for soup dumpling |
| CN104489674B (en) * | 2014-12-16 | 2017-06-16 | 北京康比特体育科技股份有限公司 | A kind of composition and its preparation for alleviating exercise induced fatigue |
| CN110193034A (en) * | 2019-05-06 | 2019-09-03 | 普正药业集团股份有限公司 | A kind of eucommia leaf extract and its application in alleviation physical fatigue product |
| CN113545483A (en) * | 2021-07-21 | 2021-10-26 | 陕西科技大学 | Aged solidified powder for benefiting spleen and stomach and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1354014A (en) * | 2001-11-29 | 2002-06-19 | 廖干甫 | Gongbu ointment |
| CN101611893A (en) * | 2008-06-25 | 2009-12-30 | 刘泳宏 | A kind of natural viscera-nourishing anticancer health-care egg and preparation method |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0130608D0 (en) * | 2001-12-21 | 2002-02-06 | Psimedica Ltd | Medical fibres and fabrics |
-
2012
- 2012-03-02 CN CN2012100537328A patent/CN102579836B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1354014A (en) * | 2001-11-29 | 2002-06-19 | 廖干甫 | Gongbu ointment |
| CN101611893A (en) * | 2008-06-25 | 2009-12-30 | 刘泳宏 | A kind of natural viscera-nourishing anticancer health-care egg and preparation method |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102579836A (en) | 2012-07-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103285231B (en) | Medicine composition for diabetes adjunctive therapy and preparation method thereof | |
| CN103877263B (en) | A kind of antifatigue health preparation of the compound Chinese medicine such as red ginseng, maca, green-tea extract (theanine) | |
| CN102579836B (en) | Traditional Chinese medical dendrobium huoshanense composition and preparation method thereof | |
| CN101513437A (en) | Antifatigue Chinese pharmaceutical composition and preparation method thereof | |
| CN101632769B (en) | Chinese medicinal composition for regulating blood sugar and preparation method thereof | |
| CN106237075A (en) | A kind of have resisting fatigue and promote the food of attention effect, health product or pharmaceutical composition and its production and use | |
| CN102362970A (en) | Traditional Chinese medicinal composition with gastrointestinal tract improvement function and preparation technology thereof | |
| CN103479691A (en) | Lipid-decreasing liver protection traditional Chinese medicine composition | |
| CN101011562A (en) | Novel formulation of shenqiwendan decoction and production method thereof | |
| CN105194421A (en) | Self-heal health-care oral solution capable of reducing blood fat and preparation method thereof | |
| CN102302609A (en) | Compound traditional Chinese drug preparation for improving subhealth | |
| CN104922299A (en) | Traditional Chinese medicine healthcare oral liquid used for preventing and treating diabetic retinopathy | |
| CN102218116B (en) | Traditional Chinese medicine for treating diabetes and preparation method thereof | |
| CN101279034B (en) | Combined Chinese medicament for curing diabetic with combined internal and external therapies and preparation thereof | |
| CN101167846A (en) | Capsule with blood sugar reducing function and preparation method thereof | |
| CN102961584A (en) | Traditional Chinese medicine composition capable of relieving fatigue, as well as preparation method and application thereof | |
| CN111358907A (en) | Medicinal and edible traditional Chinese medicine formula granule for treating insomnia and preparation method thereof | |
| CN110876772A (en) | Preparation method and application of traditional Chinese medicine preparation with liver protection function | |
| CN102784230B (en) | Pharmaceutical composition preparation for treating nutritional anemia | |
| CN103725587A (en) | Sealwort and hawthorn vinegar and production method thereof | |
| CN104337920A (en) | Traditional Chinese medicine composition for improving sleep quality | |
| CN103977390A (en) | Method for preparing ginger-onion medicinal liquor composition and application thereof | |
| CN103405574B (en) | Medicinal composition for treating hypertension | |
| CN114145374A (en) | Astragalus membranaceus and corn stigma composite tea and preparation method and application thereof | |
| CN103393938B (en) | Traditional Chinese medicine composition for reducing blood sugar |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C56 | Change in the name or address of the patentee |
Owner name: JIUXIANZUN HERBA DENDROBII CO., LTD. Free format text: FORMER NAME: ANHUI SHENGNONG BIOTECHNOLOGY TECHNOLOGY CO., LTD. |
|
| CP03 | Change of name, title or address |
Address after: Two road 237000 Lu'an Province Economic Development Zone No. 88 North Anhui Patentee after: JIUXIANZUN HUOSHAN DENDROBIUM CO., LTD. Address before: 237000 Anhui Province, Lu'an City West Road Economic Development Zone Yangtze Seiko Industrial Park Patentee before: Anhui Shengnong Biotechnology Technology Co., Ltd. |