CN102526371A - Medicine for inflammation diminishing, pain stopping, blood activating and detumescence for veterinary use and preparation method thereof - Google Patents

Abstract

The invention discloses a veterinary drug for anti-inflammatory, analgesic, blood circulation and detumescence and a preparation method thereof. The drug is composed of the following raw materials: 1-4 grams of saffron, 2-7 grams of asarum and 7-15 grams of borneol. The preparation method is as follows: immersing the above crude drug in 1000 milliliters of 85% ethanol for 72 hours, filtering and bottling the leaching solution to prepare the aerosol. The invention is convenient and quick, has remarkable curative effect, and has no toxic and side effects, and its average cure rate reaches 91% and above.

Description

Veterinary medicine for anti-inflammatory, analgesic, blood circulation and detumescence and preparation method thereof

[technical field]

The invention relates to veterinary traditional Chinese medicine, in particular to a medicine for treating surgical inflammation and pain of large animals such as cattle and horses, small animals such as pigs and sheep, and pet dogs and cats.

[Background technique]

Surgical inflammation and pain is a large category of clinical diseases, which can occur in various parts of the animal body, and can also occur in various tissues around the body, especially in skin, subcutaneous connective tissue, tendon and ligament, bone and cartilage and other tissues. Surgical inflammation and pain is a defense response of the body to stimulation, manifested as redness, swelling, heat, pain and dysfunction. Biological factors such as bacteria, viruses, rickettsia, mycoplasma, fungi, spirochetes and parasites are the most common causes of inflammation, swelling and pain. Physical factors such as high temperature, low temperature, radioactive substances and ultraviolet rays, and mechanical damage. Chemical factors such as exogenous chemical substances such as strong acid and strong alkali can cause it. Therefore, this phenomenon is widely seen in clinics, especially in small animals (dogs and cats). Western medicine mainly adopts and suppresses immunity with hormone drugs in the treatment of this symptom. Antibacterial drugs inhibit bacterial toxicity and side effects and can cause drug resistance. Antibacterial drugs are highly targeted, and are only suitable for inflammation, swelling, pain, and dysfunction caused by biological factors such as certain bacterial infections. For non-infectious inflammation, swelling, pain, and dysfunction caused by physical factors, chemical factors, etc. Its merit. Hormone drugs have large side effects and have a deep negative impact on the body. It can cause edema, diabetes, osteoporosis, easily cause gastric mucosal damage, and induce ulcers.

[Content of the invention]

The technical problem to be solved by the present invention is to provide a veterinary drug for anti-inflammatory, analgesic, blood circulation and detumescence.

Another technical problem to be solved by the present invention is to provide a preparation method of an aerosol for veterinary anti-inflammation, analgesia, promoting blood circulation and detumescence.

For veterinary medicines for anti-inflammatory, analgesic, blood circulation and detumescence, the technical solution adopted in the present invention is a veterinary medicine for anti-inflammatory, analgesic, blood circulation and detumescence, which consists of the following raw materials: 1-4 grams of saffron, 2-7 grams of asarum, 7 grams of borneol -15 grams.

For the preparation method of veterinary anti-inflammatory, analgesic, blood circulation and detumescence aerosol, the technical scheme adopted by the present invention is that the preparation method is as follows: soak the above-mentioned crude drug in 1000 ml of 85% ethanol for 72 hours, filter the leachate and bottle it to make aerosol agent.

The solution of the present invention is based on the pathogenesis of inflammation and pain in animal surgery and the treatment principles of traditional Chinese veterinary medicine. With reference to the pharmacological research of modern Chinese medicine, it is composed of drugs for promoting blood circulation and removing blood stasis, dispelling wind and relieving pain, and reducing swelling and antisepsis. It can inhibit bacteria, relieve pain, remove blood stasis, and regenerate, so as to achieve the purpose of solving surgical inflammation and pain.

Drug mechanism of the present invention is as follows:

Saffron is flat in nature and sweet in taste, non-toxic, light in weight and moist in body. Ruxue Xingsan has the effects of promoting blood circulation and dispelling blood stasis, dispelling stagnation and opening knots, cooling blood and detoxifying. Cure mainly postpartum blood stasis abdominal pain, tumbling and swelling. Modern pharmacological studies have found that saffron can inhibit oxygen free radicals, thereby achieving anti-oxidation; saffron also has the functions of stimulating the uterus, promoting blood circulation and stopping bleeding, anti-nephritis, and promoting blood flow in retinal arteries. Modern pharmacological research has discovered

Herba Asari is pungent in the mouth, warms and dispels wind, dispels cold. Functions and indications: running water, resuscitating. Control wind-cold headache, nasal sinusitis, toothache, phlegm retention and cough, rheumatic arthralgia. Modern pharmacological studies have found that Asarum has antipyretic, analgesic and local anesthetic sedative properties; its volatile oil has analgesic effects on rabbits, and its analgesic strength is equivalent to that of antipirin 0.5 mg/kg. Oral administration of water decoction also has an analgesic effect on mice. In addition, it also has anti-inflammatory, immunosuppressive and anti-allergic effects; antibacterial effect: alcohol infusions, volatile oils, etc. have inhibitory effects on various Gram-positive bacteria, various bacilli and various fungi.

Borneolum is pungent in the mouth, bitter, cool in nature. Function: open all orifices, disperse stagnant fire, remove nebula and improve eyesight, reduce swelling and relieve pain. Indications: apoplexy, fever, coma, convulsions, epilepsy, phlegm confusion, air-occlusion deafness, sore throat, aphtha, otitis media, carbuncle, hemorrhoids, red eyes and film, pinworms. "Compendium": treat sore throat, brain pain, snort, toothache; "meeting medical mirror": treat joint pain. "Haiyao Materia Medica": three worms, five hemorrhoids, Li Gao: bone pain. Modern pharmacological research has found: antibacterial and anti-inflammatory effects. In vitro experiments showed that higher concentration of borneol (0.5%) has antibacterial effect. Synthetic borneol and natural borneol have the same antibacterial effect. Analgesic effect: The compound preparation Bingsha tincture containing borneol and Bingxing liquid plus Xinhuang tablet have achieved certain therapeutic effect in the treatment of cancer pain. The analgesic and anti-inflammatory effects of borneol on burn wounds, the experimental results show that the animal model disease threshold of the borneol group is 2.78 times and 6.24 times higher than that of Jingwanhong group (positive control) and normal saline group (negative control group). Borneol also has the effect of promoting the transdermal absorption of other drugs, and can promote the transdermal absorption of triamcinolone.

Veterinary medicine theory of traditional Chinese medicine believes that the main mechanism of swelling and pain is blockage of tendons and vessels, which causes pain like blood stasis blocking collaterals, and blockage of meridians and collaterals causes pain if it is not painful. Exogenous cold, exogenous wind, exogenous heat, exogenous dampness, trauma, fatigue injury all can cause swelling and pain. "Internal Classics": "Pain sufferers with a lot of cold air", Asarum is pungent in taste, warming and expelling wind, and expelling cold is the root cause. On the basis of the theory of etiology in the "Internal Classics", Li Dongheng, a medical inventor in the Jin and Yuan dynasties, first proposed the theory of pathogenesis that "pain is unreasonable", and established that "pain decreases with benefit, and when the meridian is unblocked, the pain will go away." The principle of pain relief. In the Qing Dynasty, Ye Tiantu proposed the pathogenesis theory of "long-term pain entering the collaterals" in "Clinical Guide to Medical Cases". Wang Qingren's "Yilin Gaicuo" and Tang Rongchuan's "Blood Syndrome" further elaborated on the pathogenesis of congestion-induced pain. Saffron and Borneol promote blood circulation and remove blood stasis, dredge collaterals and dissipate stagnation. Saffron, borneol, and asarum three flavors achieve the effect of treating swelling and pain.

The beneficial effects of the present invention are:

As a pure traditional Chinese medicine aerosol, it can restore the function of tissues or organs through anti-inflammatory, detumescence and pain relief for surgical inflammation and pain. It has the characteristics of simple production, convenient use, quick effect and remarkable curative effect. Its average cure rate Up to 91% and above.

[Detailed ways]

The present invention will be further described below in conjunction with 3 embodiments:

Example 1:

1. Formula: 1 gram of saffron; 2 grams of asarum; 7 grams of borneol.

2. Preparation method:

(1) Pulverize the above into fine powder (300 mesh), soak the drug fine powder in 1000 ml of 85% ethanol for 72 hours, and filter.

(2) Bottle the filtrate to make an aerosol.

3. Therapeutic effect: The curative effect statistics of this embodiment are as shown in Table 1.

Table 1

As shown in Table 1, the average cure rate of 909 cases was 91%.

Example 2:

1. Formula: 2 grams of saffron; 5 grams of asarum; 11 grams of borneol.

2, preparation method: with embodiment 1.

3. Therapeutic effect: The curative effect statistics of this embodiment are as shown in Table 2.

Table 2:

As shown in Table 2, the average cure rate of 1913 cases was 96.4%.

Example 3:

1. Formula: 4 grams of saffron; 7 grams of asarum; 15 grams of borneol.

2, preparation method: with embodiment 1.

3. Therapeutic effect: The curative effect statistics of this embodiment are as shown in Table 3.

table 3:

As shown in Table 3, the average cure rate of 403 cases was 94.6%.

Claims (2)

1. A veterinary drug for anti-inflammatory, analgesic, blood circulation and detumescence, characterized in that it consists of the following raw materials: 1-4 grams of Saffron, 2-7 grams of Asarum, and 7-15 grams of Borneol. 2. The aerosol made from anti-inflammatory, analgesic, blood-activating and detumescent drugs according to claim 1, characterized in that the preparation method is as follows: soak the above-mentioned crude drug in 1000 milliliters of 85% ethanol for 72 hours, filter the leachate and bottle it to make aerosol.