CN102327380B - Chinese medicinal composition for treating knee osteoarthritis - Google Patents
Chinese medicinal composition for treating knee osteoarthritis Download PDFInfo
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Abstract
The invention relates to a Chinese medicinal composition for treating knee osteoarthritis. The Chinese medicinal composition consists of the following Chinese medicinal raw materials by weight: 10 to 30 grams of prepared rehmannia root, 10 to 30 grams of malaytea scurfpea fruit, 10 to 30 grams of epimedium herb, 10 to 40 grams of Chinese taxillus twig, 10 to 30 grams of Himalayan teasel root, 10 to 30 grams of east asian tree fern rhizome, 10 to 40 grams of white paeony root, 10 to 30 grams of kudzuvine root, 10 to 30 grams of papaya, 5 to 20 grams of chaff flower root, 10 to 30 grams of clematis root, 10 to 30 grams of yanhusuo, 10 to 30 grams of eucommia bark, 5 to 20 grams of safflower, 10 to 40 grams of Chinese angelica and 5 to 15 grams of honey-fried liquoric root. The Chinese medicinal composition has the effects of tonifying liver and kidney, strengthening muscles and bones, clearing heat and expelling damp, tonifying qi and blood and eliminating cold and dredging collaterals, and has a reliable curative effect on knee osteoarthritis. The composition is easy and convenient to prepare, wide in medicinal source and mild in medicinal properties of ingredients, and does not have any side effect.
Description
Technical field
The present invention relates to a kind of not medicinal preparation of definite structure of traditional herbal medicines, especially a kind of Chinese medicine composition for the treatment of knee joint osseous arthritis.
Background technology
Knee joint osseous arthritis is a kind of chronic joint disease, and its main change is degeneration and the insecondary hyperosteogeny of articular cartilage face, is mainly in middle-aged and elderly people.Main manifestations is arthralgia and movable dumb, and x-ray performance joint space narrows down, and subchondral bone matter is fine and close, and bone trabecula fracture, has sclerosis and cystis degeneration, and there is lip sample hypertrophy at edge, joint, later stage epiphysis distortion, and articular surface is uneven.Intraarticular cartilage peels off, and the cracked joint that enters of sclerotin forms articular mobile corpus.This pathological changes also can have influence on synovium of joint, and at pathological changes acute attack stage, synovial membrane hyperemia, edema, synovial membrane thicken, and synovial fluid secretion increases.Due to articular cartilage wearing and tearing regression, can there is series of symptoms and sign clinically, comprise arthralgia, swelling, deformity, dysfunction.The each outbreak of this disease often has certain inducement, as tired, activity increases, has a cold etc.But with pathological changes, increase the weight of, the hypotelorism that at every turn shows effect, the persistent period of at every turn showing effect extends, and finally can have a strong impact on function of joint, and quality of life significantly declines.
At present, there is no the medicine that reverses or end this disease progression.Treatment be all ease the pain, relief of symptoms, Saving cortilage function be in case maimed person is object.Its Therapeutic Method comprises naturopathy, Drug therapy and surgical operation.Wherein, physiotherapy: adopt thermotherapy, hydrotherapy, infrared ray, ultrashort wave, electricity irritation etc. all can strengthen local blood circulation, alleviate muscular tone, the symptom such as ease the pain.Drug therapy: current the most frequently used medicine has nonsteroidal anti inflammatory analgesic, for example U.S. good fortune of indole, ibuprofen, diclofenac, meloxicam; Simple analgesic has acetaminophen, tramadol; Muscle relaxant is as eperisone; Hormones is as betamethasone; Repair of cartilage medicine is as chondroitin sulfate, glucosamine; In medicine for external use, there are diclofenac Emulsion, etofenamate; Local injection medicine has hyaluronate sodium etc.Operative treatment: because its wound is large, dangerous high, often do not accepted by patient.
The traditional Chinese medical science is thought: liver governing tendons, kidney governing bones.Liver and kidney is full, and muscle strength is strong, the sliding profit in joint.After the middle age, Liver and kidney is virtual loss gradually, insufficiency of vital energy and blood, and muscles and bones is lost it and is supported, and muscle cartilage withers, or invades in round wind-cold damp pathogen of holding concurrently, and easily sends out primary disease.If knee wound, strain, QI-blood circulation is not smooth, and passages through which vital energy circulates is obstructed, and causes muscles and bones lose to support and fall ill, and is multiplely born in person between twenty and fifty.
According to theory of Chinese medical science, for the knee joint osseous arthritis pathogeny of the traditional Chinese medical science, take invigorating the liver and kidney, bone and muscle strengthening, wind-damp dispelling, QI invigorating, invigorate blood circulation as the rule for the treatment of, carry out dialectical composition of prescription, to reach the object that delays or end the development of this disease.
Summary of the invention
For overcome prior art Chinese medicine and western medicine and naturopathy knee joint osseous arthritis can only play ease the pain, the deficiency of relief of symptoms, in order to overcome deficiency of the prior art, the invention provides a kind ofly prepare conveniently, medicine source is wide, evident in efficacy, the Chinese medicine composition of the treatment knee joint osseous arthritis that has no side effect.
The technical solution adopted for the present invention to solve the technical problems is: a kind of Chinese medicine composition for the treatment of knee joint osseous arthritis, is characterized in that: its raw material of Chinese medicine by following weight forms: Radix Rehmanniae Preparata 10～30g, Fructus Psoraleae 10～30g, Herba Epimedii 10～30g, Herba Taxilli 10～40g, Radix Dipsaci 10～30g, Rhizoma Cibotii 10～30g, the Radix Paeoniae Alba 10～40g, Radix Puerariae 10～30g, Fructus Chaenomelis 10～30g, Radix Achyranthis Bidentatae 5～20g, Radix Clematidis 10～30g, Rhizoma Corydalis 10～30g, the Cortex Eucommiae 10～30g, Flos Carthami 5～20g, Radix Angelicae Sinensis 10～40g, Radix Glycyrrhizae Preparata 5～15g.
Precedence technique scheme of the present invention is: a kind of Chinese medicine composition for the treatment of knee joint osseous arthritis, is characterized in that: its raw material of Chinese medicine by following weight forms: Radix Rehmanniae Preparata 20g, Fructus Psoraleae 20g, Herba Epimedii 20g, Herba Taxilli 30g, Radix Dipsaci 20g, Rhizoma Cibotii 20g, Radix Paeoniae Alba 30g, Radix Puerariae 20g, Fructus Chaenomelis 20g, Radix Achyranthis Bidentatae 10g, Radix Clematidis 20g, Rhizoma Corydalis 20g, Cortex Eucommiae 20g, Flos Carthami 12g, Radix Angelicae Sinensis 30g, Radix Glycyrrhizae Preparata 6g.
Chinese medicine composition of the present invention is under Traditional Chinese medical theory and clinical experience instruct, and take invigorating the liver and kidney, bone and muscle strengthening, clearing heat and expelling damp, benefiting vital QI and blood, cold expelling dredging collateral is the rule for the treatment of, and selected medicament composing prescription delays or ends PD.In Chinese medicine composition of the present invention: Radix Rehmanniae Preparata enrich blood yin nourishing, life essence-filling, marrow-benefitting; Fructus Psoraleae reinforcing the kidney and supporting YANG, warming the spleen improving inspiration by invigorating kidney-QI; Herba Epimedii, Herba Taxilli, Radix Dipsaci, Rhizoma Cibotii, the Cortex Eucommiae, Radix Achyranthis Bidentatae have the effect of invigorating the liver and kidney, bone and muscle strengthening, wind-damp dispelling; Radix Paeoniae Alba nourishing blood to suppress the hyperactive liver, slow middle pain relieving; Radix Puerariae heat clearing away toxin expelling, pathogenic fire reducing promote the production of body fluid; Radix Clematidis expelling wind and removing dampness, removing obstruction in the collateral to relieve pain; Rhizoma Corydalis, Flos Carthami, Chinese angelica blood supplementing are invigorated blood circulation, regulating menstruation dissipating blood stasis, promoting the circulation of QI to relieve pain; Fructus Chaenomelis suppressing the hyperactive liver relaxing muscles and tendons, stomach function regulating removing dampness; Radix Glycyrrhizae Preparata spleen reinforcing stomach function regulating, Yiqi and vein recovery.The selected medicament composing prescription of the present invention, its drug component is through dialectical compatibility, complements each other using, and has synergism, and its drug effect is better than the effect of single medicine.The component of the present composition all adopts natural botanical herbs raw material, and its preparation is easy, medicine source is wide, cost is low.
The present invention follows the prescriptions principle of the traditional Chinese medical science, and various component drug adopt the use that is decocted in water for oral dose.Through clinical practice checking, it is evident in efficacy reliable, and the property of medicine is gentle, does not occur toxic and side effects, and effective percentage reaches 95%.
The specific embodiment
Below in conjunction with embodiment, the present invention will be further described.
Embodiment 1
Treat a Chinese medicine composition for knee joint osseous arthritis, its raw material of Chinese medicine by following weight forms: Radix Rehmanniae Preparata 20g, Fructus Psoraleae 20g, Herba Epimedii 20g, Herba Taxilli 30g, Radix Dipsaci 20g, Rhizoma Cibotii 20g, Radix Paeoniae Alba 30g, Radix Puerariae 20g, Fructus Chaenomelis 20g, Radix Achyranthis Bidentatae 10g, Radix Clematidis 20g, Rhizoma Corydalis 20g, Cortex Eucommiae 20g, Flos Carthami 12g, Radix Angelicae Sinensis 30g, Radix Glycyrrhizae Preparata 6g.
Embodiment 2
Treat a Chinese medicine composition for knee joint osseous arthritis, its raw material of Chinese medicine by following weight forms: Radix Rehmanniae Preparata 10g, Fructus Psoraleae 15g, Herba Epimedii 30g, Herba Taxilli 10g, Radix Dipsaci 15g, Rhizoma Cibotii 15g, Radix Paeoniae Alba 20g, Radix Puerariae 30g, Fructus Chaenomelis 30g, Radix Achyranthis Bidentatae 5g, Radix Clematidis 25g, Rhizoma Corydalis 10g, Cortex Eucommiae 15g, Flos Carthami 10g, Radix Angelicae Sinensis 20g, Radix Glycyrrhizae Preparata 10g.
Embodiment 3
Treat a Chinese medicine composition for knee joint osseous arthritis, its raw material of Chinese medicine by following weight forms: Radix Rehmanniae Preparata 30g, Fructus Psoraleae 10g, Herba Epimedii 15g, Herba Taxilli 20g, Radix Dipsaci 30g, Rhizoma Cibotii 10g, Radix Paeoniae Alba 25g, Radix Puerariae 15g, Fructus Chaenomelis 25g, Radix Achyranthis Bidentatae 15g, Radix Clematidis 10g, Rhizoma Corydalis 25g, Cortex Eucommiae 30g, Flos Carthami 5g, Radix Angelicae Sinensis 15g, Radix Glycyrrhizae Preparata 5g.
Embodiment 4
Treat a Chinese medicine composition for knee joint osseous arthritis, its raw material of Chinese medicine by following weight forms: Radix Rehmanniae Preparata 25g, Fructus Psoraleae 25g, Herba Epimedii 10g, Herba Taxilli 15g, Radix Dipsaci 25g, Rhizoma Cibotii 30g, Radix Paeoniae Alba 15g, Radix Puerariae 25g, Fructus Chaenomelis 10g, Radix Achyranthis Bidentatae 20g, Radix Clematidis 15g, Rhizoma Corydalis 30g, Cortex Eucommiae 10g, Flos Carthami 20g, Radix Angelicae Sinensis 10g, Radix Glycyrrhizae Preparata 15g.
Embodiment 5
Treat a Chinese medicine composition for knee joint osseous arthritis, its raw material of Chinese medicine by following weight forms: Radix Rehmanniae Preparata 15g, Fructus Psoraleae 5g, Herba Epimedii 25g, Herba Taxilli 35g, Radix Dipsaci 10g, Rhizoma Cibotii 25g, Radix Paeoniae Alba 10g, Radix Puerariae 10g, Fructus Chaenomelis 15g, Radix Achyranthis Bidentatae 10g, Radix Clematidis 30g, Rhizoma Corydalis 15g, Cortex Eucommiae 25g, Flos Carthami 15g, Radix Angelicae Sinensis 25g, Radix Glycyrrhizae Preparata 8g.
Chinese medicine composition in embodiment of the present invention decocting method is routinely produced medicament, and concrete grammar is as follows: the raw material of Chinese medicine of prescription is put into container, add cold water and cover powder, soak 15～20 minutes, then add water and do not have approximately 5 centimetres of powder, decoct.At a simmer, adopt intense fire to decoct, after boiling, use slow fire boiling 20～30 minutes; Second decocts, and after water boils, decocts 15～20 minutes.Decoct extracting juice twice, merge.
Treat a Chinese medicine composition for knee joint osseous arthritis, clinical efficacy is summed up:
One, general data: this Chinese medicine composition is applied to clinical observation case 60 examples, male 36 examples wherein, female's 24 examples, 30～70 years old its age.The course of disease 5 months～18 years.X-ray is taken the photograph sheet all has knee joint osseous arthritis disease in various degree to resemble, and tibia ankle all comes to a point, tibia border sclerosis, and bony spur forms, and joint space narrows down, and some cases presents osteoporotic performance.
Two, usage and dosage: during clinical practice, the component in compositions is taken the circumstances into consideration increase and decrease according to patient's body weight and age.This Chinese medicine composition potion on the one, the about 300ml of twice extracting juice of decocting, minute morning, evening take for twice.
Three, criterion of therapeutical effect: alleviate degree and range of motion is improved as criterion of therapeutical effect with symptom.
(1), clinical cure: pain disappears, and it is normal that joint motion can recover;
(2), effective: pain obviously alleviates, and movable function improves;
(3), effective: pain alleviates to some extent, and activity makes moderate progress;
(4), invalid: arthralgia and range of activity are without improvement.
Four, therapeutic effect: in this clinical observation case, take medicine after 1-6 month, recovery from illness 12 examples, follow up a case by regular visits to and have no recurrence; Effective 30 examples, effective 15 examples, invalid 3 examples.During treatment, there is not toxic and side effects.
Five, model case:
Case 1
Lee, man, 65 years old.Two knee joints are weak, pain, squat down limited 8 years, increase the weight of March.Take medicament 1 month prepared by Chinese medicine composition of the present invention, double knee joint pain obviously alleviates, and the function of squatting down is obviously improved; The check in 2 months that continues to take medicine, two knee joints are weak, pain disappears, squat down and recover normal; Continue to strengthen and take medicine 1 month, follow up a case by regular visits to and have no recurrence half a year.
Case 2
Cai, women, 60 years old, right knee joint swelled and ache 4 months, increased the weight of 1 week; Left knee joint swells and ache 3 years, increases the weight of January.Before 3 years, without obvious inducement, there is left kneed pain symptom, above, symptom is attached most importance to while going downstairs.There is in the recent period left kneed swelling, pain symptom aggravation.Take medicament 1 month prepared by Chinese medicine composition of the present invention, double knee joint pain alleviates greatly, and left knee joint swelling alleviates, and right knee joint is swollen to disappear; The check in 2 months that continues to take medicine, the swollen pain of double knee joint disappears, and movable walking is normal.
Case 3
Zhang, female, 51 years old.When medical: double knee joint pain 4 years, limitation of activity, can not squat down, goes to toilet, above go downstairs and be difficult.Through looking into: its bilateral knee joint portion mild swelling, local tenderness (+), X-ray film shows: double knee joint gap turn narrow, edge, joint hyperosteogeny, tibia spinous process of tibia comes to a point.Take medicament 4 months prepared by Chinese medicine composition of the present invention, bilateral knee arthroncus is disappeared, and presses without pain, and movable walking is normal.
Claims (1)
1. a Chinese medicine composition for the treatment of knee joint osseous arthritis, is characterized in that: its raw material of Chinese medicine by following weight forms: Radix Rehmanniae Preparata 20g, Fructus Psoraleae 20g, Herba Epimedii 20g, Herba Taxilli 30g, Radix Dipsaci 20g, Rhizoma Cibotii 20g, Radix Paeoniae Alba 30g, Radix Puerariae 20g, Fructus Chaenomelis 20g, Radix Achyranthis Bidentatae 10g, Radix Clematidis 20g, Rhizoma Corydalis 20g, Cortex Eucommiae 20g, Flos Carthami 12g, Radix Angelicae Sinensis 30g, Radix Glycyrrhizae Preparata 6g.
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| CN102908510B (en) * | 2012-11-14 | 2014-01-15 | 牛福文 | Decoction for treating knee osteoarthritis |
| CN103230484B (en) * | 2013-04-17 | 2014-10-29 | 贾古友 | Drug for treating knee osteoarthritis of patients under age of 40 |
| CN103251852B (en) * | 2013-05-28 | 2016-01-13 | 陈金宗 | A kind of medicine coordinating super micro knife to treat osteoarthritis |
| CN103316227A (en) * | 2013-07-01 | 2013-09-25 | 郑福来 | Medicine composition for treating rheumatic diseases in muscles and bones and preparation method thereof |
| CN104547245A (en) * | 2015-01-16 | 2015-04-29 | 周庆攸 | Healthy medicinal liquor and preparation method thereof |
| CN104983920A (en) * | 2015-07-30 | 2015-10-21 | 济南邦文医药科技有限公司 | Traditional Chinese medicine for treating medium and advanced renal deficiency and blood stasis type knee osteoarthritis |
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| CN105663901A (en) * | 2016-03-10 | 2016-06-15 | 郎继孝 | Traditional Chinese medicine preparation for treating degenerative osteoarthropathy |
| CN105944048B (en) * | 2016-04-28 | 2019-11-05 | 辽宁中医药大学附属医院 | A kind of traditional Chinese powder medicine for application treatment osteoarthritis |
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