CN102204552A - Antibacterial composition containing enestroburin and antibiotic compound - Google Patents
Antibacterial composition containing enestroburin and antibiotic compound Download PDFInfo
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- CN102204552A CN102204552A CN2011100885181A CN201110088518A CN102204552A CN 102204552 A CN102204552 A CN 102204552A CN 2011100885181 A CN2011100885181 A CN 2011100885181A CN 201110088518 A CN201110088518 A CN 201110088518A CN 102204552 A CN102204552 A CN 102204552A
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Abstract
The invention discloses an antibacterial composition containing enestroburin and antibiotic compound, which comprises an active component A and an active component B, wherein the active component A may be enestroburin; the active component B may be any of the following antibacterial agents: validamycin, Zhongshengmycin, kasugamycin and polyoxin; and the weight part ratio of the active component A to the active component B ranges from 64:1 to 1:64. The composition disclosed by the invention can prevent and treat various diseases in crops, has an obvious synergetic effect, expands an antibacterial spectrum and has high activity for rice blast, banded sclerotial blight, Septoria nodorum, damping off, powdery mildew, leaf spot, downy mildew, blight, Botrytis, leaf mold and the like; and when the antibacterial composition is used, the dose of farm chemical is reduced, the residual farm chemical on crops is reduced, and environment pollution is relieved.
Description
Technical field
The invention belongs to technical field of pesticide, relate to a kind of bactericidal composition that contains Enestroburin and antibiotics compound.
Background technology
Enestroburin (enostroburin), molecular formula: C
22H
27ClNO
4, chemical name: α-[[[[4-(4-chlorphenyl)-Ding-3-alkene-2-base-] imido grpup] methyl] phenyl-'beta '-methoxy acrylic acid methyl esters.
Enestroburin class wide-spectrum bactericide is a class novel agrochemical of successfully developing as the bactericide lead compound from natural products Strobilurins, belongs to methoxy acrylic bactericide.The action principle of this type of medicament is to suppress the mitochondrial breathing of fungi, the Q0 position by cytochrome b c1 complex in conjunction with suppressing mitochondrial current potential transmission, the germ energy is synthetic to play bactericidal action thereby destroy.Characteristics such as having efficient, wide spectrum, protection, treat, root out, infiltration, systemic activity, resistance of rainwater washing against, lasting period are long.To 1,4-demethylation enzyme inhibitor, benzamides, the bacterial strain of dicarboxyl amine and benzimidazole generation resistance is effective, does not have cross resistance with at present existing bactericide.Nearly all Mycophytes (Ascomycetes, Basidiomycetes, Oomycete and Fungi Imperfecti) disease such as powdery mildew, rust, Ying's rot, net blotch, downy mildew, rice blast etc. all there is good activity.Except that downy mildew, eqpidemic disease are had the special efficacy, rust, powdery mildew, anthracnose, rice blast, damping off, scab all there is good activity.To crop safety, because of its at soil, capable of being fast degraded in the water, so environmentally safe.
In the real process of agricultural production, the agent of Enestroburin list is used for a long time, and easily the problem that produces is the drug-fast generation of germ.And that the different cultivars composition carries out is composite, is to prevent and treat the very common method of resistance germ.Heterogeneity is carried out composite, according to practical application effect, judge certain composite be synergy, add and or antagonism.In most cases, the composite effect of agricultural chemicals all is an additive effect, and the seldom composite of synergistic effect really arranged, especially synergistic effect very obviously, synergy ratio very high composite just still less.Through inventor's research, discovery can produce good synergistic effect with Enestroburin and jinggangmeisu, middle living rhzomorph, kasugarnycin, polyoxin after composite, and still unexposed at home and abroad about the composite relevant report of Enestroburin and jinggangmeisu, middle living rhzomorph, kasugarnycin, polyoxin.
Summary of the invention
A kind of bactericidal composition that contains Enestroburin and antibiotics compound, comprise effective active component, auxiliary agent and filler, it is characterized in that: A, B ratio of weight and number are 64: 1～1: 64, active components A is selected from Enestroburin, and active component B is selected from a kind of in antibiotics compound jinggangmeisu, middle living rhzomorph, kasugarnycin, the polyoxin.
Described a kind of bactericidal composition that contains Enestroburin and antibiotics compound is characterized in that: the ratio of weight and number of A, two kinds of active components of B is 16: 1～1: 16.
The described bactericidal composition that contains Enestroburin is characterized in that: the ratio of weight and number of Enestroburin and jinggangmeisu is 8: 1～1: 8.
The described bactericidal composition that contains Enestroburin is characterized in that: the ratio of weight and number of Enestroburin and middle living rhzomorph is 8: 1～1: 8.
The described bactericidal composition that contains Enestroburin is characterized in that: the ratio of weight and number of Enestroburin and kasugarnycin is 8: 1～1: 8.
The described bactericidal composition that contains Enestroburin is characterized in that: the ratio of weight and number of Enestroburin and polyoxin is 8: 1～1: 8.
Usually active weight percentage is 1～90% of a gross weight in the composition, and preferable is 5%～60%.According to different preparation types, the active component content scope is different.Usually, liquid preparation contains 1～60% active substance by weight, preferably is 5～50%; Solid pharmaceutical preparation contains 1～90% active substance by weight, preferably is 5～80%.
At least contain a kind of surfactant in the bactericidal composition of the present invention, the dispersion of active component in water when being beneficial to use.Surface-active contents is 5～30% of a total formulation weight amount, and surplus is solid or liquid diluent.
The selected surfactant of bactericidal composition of the present invention is known in those skilled in the art: can be selected from dispersant, wetting agent, binding agent or the defoamer one or more.According to different dosage form, can also contain disintegrant known in those skilled in the art, antifreeze etc. in the preparation.
Described wetting agent is selected from: one or more in lauryl sodium sulfate, neopelex, Nekal BX, wetting and penetrating agent F, spaonin powder, silkworm excrement, the soapberry powder.
Described dispersant is selected from alkylnaphthalene sulfonate, two (alkyl) naphthalenesulfonate formaldehyde condensation compound, naphthalene sulfonic acid-formaldehyde condensation product, aryl phenol polyoxyethylene succinate sulfonate, octylphenol polyethylene oxyethylene group ether sulfate, polycarboxylate, lignosulfonates, the phonetic formaldehyde condensation products sulphate of alkylphenol-polyethenoxy, alkyl benzene sulfonate calcium salt, the naphthalene sulfonic acid-formaldehyde condensation product sodium salt, alkylphenol-polyethenoxy is phonetic, aliphatic amine polyoxyethylene is phonetic, polyoxyethylene carboxylate, during the ester polyoxyethylene is phonetic one or more.
Described disintegrant is selected from: one or more in bentonite, urea, ammonium sulfate, the aluminium chloride.
Described binding agent is selected from: one or more in gum Arabic, xanthans, sodium phosphate trimer, phenolic resins, sodium alginate, white dextrin, methylcellulose, PAA, polyvinylpyrrolidone, crospolyvinylpyrrolidone, polyethylene glycol, the polyvinyl alcohol.
Described antifreeze is selected from: one or more in ethylene glycol, propane diols, glycerine, the polyethylene glycol.
Described defoamer is selected from: silicone, C
8～10Aliphatic alcohols, C
10～20In saturated fat acids (as capric acid) and acid amides, silicone oil, the silicone compound one or more.
Described stabilizing agent is selected from one or more in sodium sorbate, butyl glycidyl ether, phenyl glycidyl ether, cresyl glycidyl ether, the polyethylene glycol diglycidyl ether;
Described filler is selected from: one or more in kaolin, diatomite, bentonite, attapulgite, white carbon, starch, the precipitated calcium carbonate.
Composition of the present invention can be by the user before use through dilution or directly use.Its preparation can be by the preparation of common processing method, is about to active substance and after liquid flux or solid carrier mix, and adds in surfactant such as dispersant, stabilizing agent, wetting agent, adhesive, the defoamer etc. one or more again.
Bactericidal composition of the present invention can be processed into acceptable forms on any agricultural chemicals on demand, and wherein preferred dosage form has: wetting powder, water dispersible granules, suspending agent etc.
Comprise following constituent content when composition is made wetting powder: Enestroburin 1～64%, active component B 1～64%, dispersant 5～10%, wetting agent 2～10%, filler add to 100%.
Active component Enestroburin, active component B, dispersant, wetting agent, filler are mixed, in mixed cylinder, mix, after airslide disintegrating mill is pulverized, mix again, promptly can be made into wetting powder product of the present invention.
Wetting powder the key technical indexes of the present invention:
Comprise following constituent content when composition is made water dispersible granules: active component Enestroburin 1～64%, active component B 1～64%, dispersant 3～12%, wetting agent 1～8%, disintegrant 1～10%, binding agent 1～8%, filler add to 100%.
Active component Enestroburin, active component B, dispersant, wetting agent, disintegrant, filler etc. are obtained the particle diameter that needs through comminution by gas stream together, add other auxiliary agents such as binding agent again, obtain the materials of granulating.It is interior through after granulation and the drying to expect that product are quantitatively sent the fluidized bed granulation dryer to, makes water dispersible granules product of the present invention.
Water dispersible granules the key technical indexes of the present invention:
Comprise following constituent content when composition is made suspending agent: active component Enestroburin 1～50%, active component B 1～32%, dispersant 2～10%, wetting agent 2～10%, defoamer 0.1～1%, binding agent 0.1～2%, antifreeze 0.1～8%, deionized water add to 100%.
Dispersant, wetting agent, defoamer, thickener, antifreeze in the above-mentioned formulation material are mixed through high speed shear, add active component Enestroburin, active component B, ball milling is 2～3 hours in ball mill, make diameter of particle all below 5 μ m, make suspending agent product of the present invention.
Suspending agent the key technical indexes of the present invention:
The invention has the advantages that: after (1) Enestroburin and antibiotics compound are composite, have obviously lasting synergistic effect; (2) enlarged fungicidal spectrum, diseases such as rice blast, banded sclerotial blight, glume blight, damping off, powdery mildew, leaf spot, downy mildew, fusarium wilt, gray mold, leaf mold have all been had greater activity; (3) the present invention not with an organic solvent is not difficult for producing poisoning, is convenient to transportation and storage; (4) reduce the dosage of agricultural chemicals, reduced the residual quantity of agricultural chemicals on crop, alleviated environmental pollution.
Embodiment
The embodiment of the invention is the method that adopts Toxicity Determination and field trial to combine.The embodiment of the invention is the method that adopts Toxicity Determination and field trial to combine.Pass through Toxicity Determination earlier, the synergy ratio (SR) after clear and definite two kinds of medicaments are composite by a certain percentage, SR＜0.5 is an antagonism, and 0.5≤SR≤1.5 are summation action, and SR＞1.5 are synergistic effect, on this basis, carry out field trial again.
Enestroburin and active component B (B be selected from jinggangmeisu, middle living rhzomorph, kasugarnycin, the polyoxin a kind of) are composite to target germ Toxicity Determination
After the effective inhibition concentration scope of each medicament was determined in prerun, each medicament was established 5 dosage respectively by active constituent content and is handled, and established the clear water contrast.Carry out with reference to " agricultural chemicals indoor bioassay test rule bactericide ", adopt the mycelial growth rate method to measure the virulence of medicament the target germ.Measure colony diameter with the right-angled intersection method behind the 72h, calculate and respectively handle clean amount of growth, mycelial growth inhibition rate.
Clean amount of growth (mm)=measurement colony diameter-5
Mycelial growth inhibition rate is converted into probit value (y), and liquor strength (μ g/mL) converts logarithm value (x) to, tries to achieve virulence regression equation (y=a+bx) with method of least squares, and calculates the EC of every kind of medicament thus
50Value.Calculate the different proportioning synergy ratios (SR) of two medicaments according to the Wadley method simultaneously, SR＜0.5 is an antagonism, and 0.5≤SR≤1.5 are summation action, and SR＞1.5 are synergistic effect.Computing formula is as follows:
Wherein: a, b are respectively active component Enestroburin and active component B (jinggangmeisu, middle living rhzomorph, kasugarnycin, polyoxin) shared ratio in combination;
A is an Enestroburin;
B is a kind of in jinggangmeisu, middle living rhzomorph, kasugarnycin, the polyoxin.
Implementation of an application example one
Enestroburin and composite jinggangmycin are to the sick Toxicity Determination of rice sheath blight disease
Test medicine provides by Shanxi Thompson Biological Technology Co., Ltd..
Experimental scheme: effective inhibition concentration scope of determining Enestroburin, the former medicine of jinggangmeisu and the two different proportioning mixture through preliminary experiment.
Toxicity test result
Table 1 Enestroburin, jinggangmeisu and composite toxicity test analysis of results table thereof to rice sheath blight disease
As shown in Table 1, Enestroburin, jinggangmeisu are to the EC of rice sheath blight disease
50Be respectively 1.22mg/L and 1.87mg/L.Enestroburin and jinggangmeisu proportioning were at 64: 1 to 1: 64 o'clock, synergy ratio SR is all greater than 1.5, illustrating that Enestroburin and jinggangmeisu were mixed in the scope at 64: 1 to 1: 64 all shows synergistic effect, and especially when the two proportioning during at 8: 1 to 1: 8, synergistic effect is the most obvious.
Implementation of an application example two
Enestroburin and middle living rhzomorph are composite to the sigatoka Toxicity Determination
Test medicine provides by Shanxi Thompson Biological Technology Co., Ltd..
Experimental scheme: effective inhibition concentration scope of determining Enestroburin, the former medicine of middle living rhzomorph and the two different proportioning mixture through preliminary experiment.
Toxicity test result
Table 2 Enestroburin, middle living rhzomorph and composite toxicity test analysis of results table thereof to alternaria leaf spot of apple
As shown in Table 2, Enestroburin, middle living rhzomorph are to the EC of alternaria leaf spot of apple
50Be respectively 1.12mg/L and 0.74mg/L.Enestroburin and middle living rhzomorph proportioning were at 64: 1 to 1: 64 o'clock, synergy ratio SR is all greater than 1.5, illustrating that Enestroburin and middle living rhzomorph were mixed in the scope at 64: 1 to 1: 64 all shows synergistic effect, especially when the two proportioning during at 8: 1 to 1: 8, synergistic effect is more obviously outstanding.
Implementation of an application example three:
Enestroburin and kasugarnycin are composite to the wheat powdery mildew Toxicity Determination.
Test medicine provides by Shanxi Thompson Biological Technology Co., Ltd..
Experimental scheme: effective inhibition concentration scope of determining Enestroburin, the former medicine of kasugarnycin and the two different proportioning mixture through preliminary experiment.
Toxicity test result
Table 3 Enestroburin, kasugarnycin and composite toxicity test analysis of results table thereof to wheat powdery mildew
As shown in Table 3, Enestroburin, kasugarnycin are to the EC of wheat powdery mildew
50Be respectively 1.51mg/L and 0.63mg/L.Enestroburin compares at 64: 1 to 1: 64 o'clock with kasugarnycin, synergy ratio SR is all greater than 1.5, illustrating that Enestroburin and kasugarnycin were mixed in the scope at 64: 1 to 1: 64 all shows synergistic effect, and especially when the two proportioning during at 8: 1 to 1: 8, synergistic effect is more outstanding.
Implementation of an application example four
Enestroburin and polyoxin are composite to the cladosporium leaf and fruit mould of tomato Toxicity Determination
Test medicine provides by Shanxi Thompson Biological Technology Co., Ltd..
Experimental scheme: effective inhibition concentration scope of determining Enestroburin, the former medicine of polyoxin and the two different proportioning mixture through preliminary experiment.
Toxicity test result
Table 2 Enestroburin, polyoxin and composite toxicity test analysis of results table thereof to tomato downy mildew
As shown in Table 2, Enestroburin, polyoxin are to the EC of cladosporium leaf and fruit mould of tomato
50Be respectively 1.15mg/L and 1.54mg/L.Enestroburin and polyoxin proportioning were at 64: 1 to 1: 64 o'clock, synergy ratio SR is all greater than 1.5, illustrating that Enestroburin and polyoxin were mixed in the scope at 64: 1 to 1: 64 all shows synergistic effect, especially when the two proportioning during at 8: 1 to 1: 8, synergistic effect is more obviously outstanding.
Application Example four the implementation of Formulation Example
To further instruction of the present invention, the portion rate among the embodiment all is weight percentage below in conjunction with embodiment, but the present invention is not limited thereto.
Embodiment 120% Enestroburin jinggangmeisu wetting powder
Enestroburin 10%, jinggangmeisu 10%, polycarboxylate 3%, soapberry powder 4%, white carbon 8%, diatomite add to 100%, and mixture carries out comminution by gas stream, make 20% Enestroburin jinggangmeisu wetting powder.
Embodiment 235% Enestroburin jinggangmeisu wetting powder
Enestroburin 20%, jinggangmeisu 15%, lignosulfonates 3%, wetting and penetrating agent F 3%, white carbon 14%, attapulgite add to 100%, and mixture carries out comminution by gas stream, make 35% Enestroburin jinggangmeisu wetting powder.
Embodiment 365% Enestroburin jinggangmeisu wetting powder
Enestroburin 60%, jinggangmeisu 5%, aryl phenol polyoxyethylene succinate sulfonate 4%, spaonin powder 3%, white carbon add to 100%, and mixture carries out comminution by gas stream, make 65% Enestroburin jinggangmeisu wetting powder.
Embodiment 418% Enestroburin jinggangmeisu water dispersible granules
Enestroburin 2%, jinggangmeisu 16%, lauryl sodium sulfate 5%, polyoxyethylene carboxylate 3%, aluminium chloride 1%, bentonite 10%, white carbon 3%, kaolin add to 100%, the mixed 18% Enestroburin jinggangmeisu water dispersible granules that gets.
Embodiment 528% Enestroburin jinggangmeisu water dispersible granules
Enestroburin 4%, jinggangmeisu 24%, soapberry powder 3%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 4%, bentonite 10%, white carbon 5%, diatomite add to 100%, the mixed 28% Enestroburin jinggangmeisu water dispersible granules that gets.
Embodiment 645% Enestroburin jinggangmeisu water dispersible granules
Enestroburin 40%, jinggangmeisu 5%, spaonin powder 5%, alkyl benzene sulfonate calcium salt 4%, urea 1%, white carbon 22%, kaolin add to 100%, the mixed 45% Enestroburin jinggangmeisu water dispersible granules that gets.
Embodiment 715% Enestroburin jinggangmeisu suspending agent
Enestroburin 5%, jinggangmeisu 10%, polycarboxylate 5%, neopelex 5%, C
8～10Aliphatic alcohols 0.5%, methylcellulose 1%, propane diols 1.6%, deionized water add to 100%, the mixed 15% Enestroburin jinggangmeisu suspending agent that gets.
Embodiment 820% Enestroburin jinggangmeisu suspending agent
Enestroburin 4%, jinggangmeisu 16%, naphthalene sulfonic acid-formaldehyde condensation product 4%, silkworm excrement 3%, silicone compound 0.2%, polyvinylpyrrolidone 0.8%, polyethylene glycol 1.5%, deionized water add to 100%, the mixed 20% Enestroburin jinggangmeisu suspending agent that gets.
Embodiment 948% Enestroburin jinggangmeisu suspending agent
Enestroburin 40%, jinggangmeisu 8%, the phonetic formaldehyde condensation products sulphate 3% of alkylphenol-polyethenoxy, neopelex 4%, C
10～20Saturated fat acids 0.5%, sodium phosphate trimer 1%, glycerine 1.5%, deionized water add to 100%, the mixed 48% Enestroburin jinggangmeisu suspending agent that gets.
Give birth to the rhzomorph wetting powder in embodiment 1024% Enestroburin
Enestroburin 8%, middle living rhzomorph 16%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 3%, silkworm excrement 3%, white carbon 5%, diatomite add to 100%, and mixture carries out comminution by gas stream, make and give birth to the rhzomorph wetting powder in 24% Enestroburin.
Give birth to the rhzomorph wetting powder in embodiment 1145% Enestroburin
Enestroburin 30%, middle living rhzomorph 15%, polycarboxylate 3%, Nekal BX 4%, white carbon 20%, bentonite add to 100%, and mixture carries out comminution by gas stream, make and give birth to the rhzomorph wetting powder in 45% Enestroburin.
Give birth to the rhzomorph wetting powder in embodiment 1260% Enestroburin
Enestroburin 40%, middle living rhzomorph 20%, lignosulfonates 3%, soapberry powder 4%, white carbon add to 100%, and mixture carries out comminution by gas stream, make and give birth to the rhzomorph wetting powder in 60% Enestroburin.
Give birth to the rhzomorph water dispersible granules in embodiment 1330% Enestroburin
Enestroburin 10%, middle living rhzomorph 20%, the phonetic formaldehyde condensation products sulphate 3% of alkylphenol-polyethenoxy, spaonin powder 2%, urea 1%, white carbon 8%, attapulgite add to 100%, and mixed getting given birth to the rhzomorph water dispersible granules in 30% Enestroburin.
Give birth to the rhzomorph water dispersible granules in embodiment 1450% Enestroburin
Enestroburin 40%, middle living rhzomorph 10%, lignosulfonates 4%, soapberry powder 4%, ammonium sulfate 0.8%, white carbon 22%, bentonite add to 100%, and mixed getting given birth to the rhzomorph water dispersible granules in 50% Enestroburin.
Give birth to the rhzomorph water dispersible granules in embodiment 1540% Enestroburin
Enestroburin 15%, middle living rhzomorph 25%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 3%, wetting and penetrating agent F 4%, urea 5%, white carbon 12%, kaolin add to 100%, and mixed getting given birth to the rhzomorph water dispersible granules in 40% Enestroburin.
Give birth to the rhzomorph suspending agent in embodiment 1612% Enestroburin
Enestroburin 4%, middle living rhzomorph 8%, polyoxyethylene carboxylate 4%, soapberry powder 3%, silicone oil 0.3%, xanthans 1%, glycerine 1.3%, deionized water add to 100%, and mixed getting given birth to the rhzomorph suspending agent in 12% Enestroburin.
Give birth to the rhzomorph suspending agent in embodiment 1725% Enestroburin
Enestroburin 20%, middle living rhzomorph 5%, alkyl benzene sulfonate calcium salt 3%, lauryl sodium sulfate 4%, silicone compound 0.5%, sodium phosphate trimer 1.5%, ethylene glycol 1.5%, deionized water add to 100%, and mixed getting given birth to the rhzomorph suspending agent in 25% Enestroburin.
Give birth to the rhzomorph suspending agent in embodiment 1840% Enestroburin
Enestroburin 10%, middle living rhzomorph 30%, polycarboxylate 3%, wetting and penetrating agent F 5%, silicone oil 0.2%, polyvinylpyrrolidone 1%, polyethylene glycol 1.6%, deionized water add to 100%, and mixed getting given birth to the rhzomorph suspending agent in 40% Enestroburin.
Embodiment 1918% Enestroburin kasugarnycin wetting powder
Enestroburin 6%, kasugarnycin 12%, the phonetic formaldehyde condensation products sulphate 3% of alkylphenol-polyethenoxy, silkworm excrement 3%, white carbon 4%, bentonite add to 100%, and mixture carries out comminution by gas stream, make 18% Enestroburin kasugarnycin wetting powder.
Embodiment 2050% Enestroburin kasugarnycin wetting powder
Enestroburin 40%, kasugarnycin 10%, lignosulfonates 3%, spaonin powder 5%, white carbon 18%, diatomite add to 100%, and mixture carries out comminution by gas stream, make 50% Enestroburin kasugarnycin wetting powder.
Embodiment 2165% Enestroburin kasugarnycin wetting powder
Enestroburin 64%, kasugarnycin 1%, polyoxyethylene carboxylate 3%, wetting and penetrating agent F 4%, white carbon add to 100%, and mixture carries out comminution by gas stream, make 65% Enestroburin kasugarnycin wetting powder.
Embodiment 229% Enestroburin kasugamycin water-dispersion granule
Enestroburin 8%, kasugarnycin 1%, aryl phenol polyoxyethylene succinate sulfonate 3%, Nekal BX 4%, sodium sulphate 1%, white carbon 8%, bentonite add to 100%, the mixed 9% Enestroburin kasugamycin water-dispersion granule that gets.
Embodiment 2325% Enestroburin kasugamycin water-dispersion granule
Enestroburin 20%, kasugarnycin 5%, aliphatic amine polyoxyethylene are phonetic 3%, wetting and penetrating agent F 3%, aluminium chloride 0.8%, white carbon 10%, attapulgite add to 100%, mixed 25% Enestroburin kasugamycin water-dispersion granule.
Embodiment 2445% Enestroburin kasugamycin water-dispersion granule
Enestroburin 40%, kasugarnycin 5%, naphthalene sulfonic acid-formaldehyde condensation product 4%, soapberry powder 5%, urea 1.2%, white carbon 24%, bentonite add to 100%, the mixed 45% Enestroburin kasugamycin water-dispersion granule that gets.
Embodiment 2527% Enestroburin kasugarnycin suspending agent
Enestroburin 18%, kasugarnycin 9%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 4%, neopelex 3%, C
8～10Aliphatic alcohols 0.7%, gum Arabic 0.8%, glycerine 1.4%, deionized water add to 100%, the mixed 27% Enestroburin kasugarnycin suspending agent that gets.
Embodiment 2633% Enestroburin kasugarnycin suspending agent
Enestroburin 32%, kasugarnycin 1%, alkyl benzene sulfonate calcium salt 3%, wetting and penetrating agent F 4%, silicone oil 0.2%, polyvinylpyrrolidone 1%, polyethylene glycol 1.7%, deionized water add to 100%, the mixed 33% Enestroburin kasugarnycin suspending agent that gets.
Embodiment 2740% Enestroburin kasugarnycin suspending agent
Enestroburin 32%, kasugarnycin 8%, polyoxyethylene carboxylate 5%, soapberry powder 2%, silicone compound 0.5%, sodium phosphate trimer 0.6%, propane diols 1.2%, deionized water add to 100%, the mixed 40% Enestroburin kasugarnycin suspending agent that gets.
Embodiment 2820% Enestroburin polyoxin wetting powder
Enestroburin 12%, polyoxin 8%, polycarboxylate 3%, soapberry powder 4%, white carbon 8%, diatomite add to 100%, and mixture carries out comminution by gas stream, make 20% Enestroburin polyoxin wetting powder.
Embodiment 2935% Enestroburin polyoxin wetting powder
Enestroburin 25%, polyoxin 10%, lignosulfonates 3%, wetting and penetrating agent F 3%, white carbon 18%, attapulgite add to 100%, and mixture carries out comminution by gas stream, make 35% Enestroburin polyoxin wetting powder.
Embodiment 3065% Enestroburin polyoxin wetting powder
Enestroburin 60%, polyoxin 5%, aryl phenol polyoxyethylene succinate sulfonate 4%, spaonin powder 3%, white carbon add to 100%, and mixture carries out comminution by gas stream, make 65% Enestroburin polyoxin wetting powder.
Embodiment 3118% Enestroburin polyoxin water dispersible granules
Enestroburin 3%, polyoxin 15%, lauryl sodium sulfate 5%, polyoxyethylene carboxylate 3%, aluminium chloride 1%, white carbon 2%, bentonite 10%, kaolin add to 100%, the mixed 18% Enestroburin polyoxin water dispersible granules that gets.
Embodiment 3228% Enestroburin polyoxin water dispersible granules
Enestroburin 18%, polyoxin 10%, soapberry powder 3%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 4%, bentonite 10%, white carbon 8%, white carbon 13%, diatomite add to 100%, the mixed 28% Enestroburin polyoxin water dispersible granules that gets.
Embodiment 3345% Enestroburin polyoxin water dispersible granules
Enestroburin 42%, polyoxin 3%, spaonin powder 5%, alkyl benzene sulfonate calcium salt 4%, urea 1%, white carbon 28%, kaolin add to 100%, the mixed 45% Enestroburin polyoxin water dispersible granules that gets.
Embodiment 3415% Enestroburin polyoxin suspending agent
Enestroburin 5%, polyoxin 10%, polycarboxylate 5%, neopelex 5%, C
8～10Aliphatic alcohols 0.5%, methylcellulose 1%, propane diols 1.6%, deionized water add to 100%, the mixed 15% Enestroburin polyoxin suspending agent that gets.
Embodiment 3520% Enestroburin polyoxin suspending agent
Enestroburin 5%, polyoxin 15%, naphthalene sulfonic acid-formaldehyde condensation product 4%, silkworm excrement 3%, silicone compound 0.2%, polyvinylpyrrolidone 0.8%, polyethylene glycol 1.5%, deionized water add to 100%, the mixed 20% Enestroburin polyoxin suspending agent that gets.
Embodiment 3648% Enestroburin polyoxin suspending agent
Enestroburin 42%, polyoxin 6%, the phonetic formaldehyde condensation products sulphate 3% of alkylphenol-polyethenoxy, neopelex 4%, C
10～20Saturated fat acids 0.5%, sodium phosphate trimer 1%, glycerine 1.5%, deionized water add to 100%, the mixed 48% Enestroburin polyoxin suspending agent that gets.
The ratio of A, two kinds of active components of B can be adjusted in 64: 1～1: 64 synergy scope in the foregoing description, thereby forms new embodiment.
Application Example five Enestroburins and jinggangmeisu and the composite rice sheath blight disease test of pesticide effectiveness of preventing and treating thereof
This experimental establishment is in suburb, Guangxi province Liuzhou City, and test medicine is researched and developed, provided by Shanxi Thompson Biological Technology Co., Ltd., contrast medicament 25% Enestroburin missible oil (commercial), 10% jinggangmeisu aqua (commercial).
The preceding investigation of medicine rice sheath blight disease disease index, in the their early stage dispenser, dispenser for the second time after 10 days, dispenser is 2 times altogether, investigates disease indexs in 3 days, 21 days after the dispenser for the second time and calculates preventive effect.Experimental result is as follows:
Table 4 Enestroburin, jinggangmeisu and the composite rice sheath blight disease test of pesticide effectiveness of preventing and treating thereof
As can be seen from Table 4, can effectively prevent and treat rice sheath blight disease behind Enestroburin and the composite jinggangmycin, control efficiency all is better than the preventive effect of single agent.In the test scope of medication target crop is had no adverse effects, and the rice blast disease is had good preventive effect, preventive effect reaches more than 90%.
Application Example six Enestroburins and middle living rhzomorph and the composite ring rot of apple test of pesticide effectiveness of preventing and treating thereof
This experimental establishment is in the Liquan County, Shaanxi Province, and test medicine is researched and developed, provided by Shanxi Thompson Biological Technology Co., Ltd., gives birth to rhzomorph wetting powder (commercial) in the contrast medicament 25% Enestroburin missible oil (commercial), 3%.
The investigation ring rot of apple state of an illness before the medicine, in the dispenser for the first time of state of an illness initial stage, dispenser in per 7 days once is total to dispenser 3 times.Investigated disease index respectively and calculated preventive effect in 3 days, 21 days after the dispenser for the third time.Experimental result is as follows:
Table 5 Enestroburin, middle living rhzomorph and the composite ring rot of apple test of pesticide effectiveness of preventing and treating thereof
As can be seen from Table 5, can effectively prevent and treat ring rot of apple after Enestroburin and middle living rhzomorph are composite, control efficiency all is better than the preventive effect of single agent.In the test scope of medication target crop is had no adverse effects, and alternaria leaf spot of apple is had good preventive effect, preventive effect reaches more than 91%.
Application Example seven Enestroburins and kasugarnycin and the composite control rice blast test of pesticide effectiveness thereof
This experimental establishment is in Jidong County, Heilongjiang Province, and test medicine is researched and developed, provided by Shanxi Thompson Biological Technology Co., Ltd., contrast medicament 25% Enestroburin missible oil (commercial), 2% kasugarnycin aqua (commercial).
The preceding investigation of medicine rice blast disease index, in the their early stage dispenser, dispenser for the second time after 7 days, dispenser is 2 times altogether, investigates disease indexs in 3 days, 21 days after the dispenser for the second time and calculates preventive effect.Experimental result is as follows:
Table 6 Enestroburin, kasugarnycin and the composite control rice blast test of pesticide effectiveness thereof
As can be seen from Table 6, can effectively prevent and treat rice blast after Enestroburin and kasugarnycin are composite, control efficiency all is better than the preventive effect of single agent.In the test scope of medication, the target crop is had no adverse effects.
Application Example eight Enestroburins and polyoxin and the composite control tomato late blight test of pesticide effectiveness thereof
This experimental establishment is in suburb, Tianshui, Gansu Province, and test medicine is researched and developed, provided by Shanxi Thompson Biological Technology Co., Ltd., contrast medicament 25% Enestroburin missible oil (commercial), 10% polyoxin wetting powder (commercial).
The investigation tomato late blight state of an illness before the medicine, in the dispenser for the first time of state of an illness initial stage, dispenser in per 7 days once is total to dispenser 2 times.Investigated disease index respectively and calculated preventive effect in 3 days, 21 days after the dispenser for the second time.Experimental result is as follows:
Table 7 Enestroburin, polyoxin and the composite control tomato late blight test of pesticide effectiveness thereof
As can be seen from Table 7, can effectively prevent and treat tomato late blight after Enestroburin and polyoxin are composite, control efficiency all is better than the preventive effect of single agent.In the test scope of medication, the target crop is had no adverse effects.
Claims (9)
1. bactericidal composition that contains Enestroburin and antibiotics compound, comprise effective active component, auxiliary agent and filler, it is characterized in that: two kinds of active component ratios of weight and number of A, B are 64: 1～1: 64, described A is selected from Enestroburin, and B is selected from a kind of in antibiotics compound jinggangmeisu, middle living rhzomorph, kasugarnycin, the polyoxin.
2. bactericidal composition according to claim 1 is characterized in that: the ratio of weight and number of A, two kinds of active components of B is 16: 1～1: 16.
3. bactericidal composition according to claim 2 is characterized in that: the ratio of weight and number of Enestroburin and jinggangmeisu is 8: 1～1: 8.
4. bactericidal composition according to claim 2 is characterized in that: the ratio of weight and number of Enestroburin and middle living rhzomorph is 8: 1～1: 8.
5. bactericidal composition according to claim 2 is characterized in that: the ratio of weight and number of Enestroburin and kasugarnycin is 8: 1～1: 8.
6. bactericidal composition according to claim 2 is characterized in that: the ratio of weight and number of Enestroburin and polyoxin is 8: 1～1: 8.
7. bactericidal composition according to claim 1 is characterized in that: wherein the effective active component content accounts for 1～80% of gross weight.
8. bactericidal composition according to claim 7 is characterized in that: wherein the effective active component content accounts for 5～60% of gross weight.
9. bactericidal composition according to claim 1 is used to prevent and treat rice blast, banded sclerotial blight, glume blight, damping off, powdery mildew, leaf spot, downy mildew, fusarium wilt, gray mold, leaf mold.
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| Application Number | Priority Date | Filing Date | Title |
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| CN2011100885181A CN102204552A (en) | 2011-04-09 | 2011-04-09 | Antibacterial composition containing enestroburin and antibiotic compound |
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| Application Number | Priority Date | Filing Date | Title |
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| CN2011100885181A CN102204552A (en) | 2011-04-09 | 2011-04-09 | Antibacterial composition containing enestroburin and antibiotic compound |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102972402A (en) * | 2012-12-18 | 2013-03-20 | 陕西绿盾生物制品有限责任公司 | Kasugamycin-containing pesticide composition |
| CN103039449A (en) * | 2011-10-11 | 2013-04-17 | 陕西上格之路生物科学有限公司 | Bactericidal composition |
| CN106172453A (en) * | 2015-04-29 | 2016-12-07 | 深圳诺普信农化股份有限公司 | A kind of bactericidal composition and application thereof |
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| EP0936213B1 (en) * | 1998-02-10 | 2003-03-26 | Dow AgroSciences LLC | Unsaturated oxime ethers and their use as fungicides and insecticides |
| CN1957699A (en) * | 2006-11-24 | 2007-05-09 | 华南理工大学 | Micellar emulsion prepared by mixing Kresoxim and jinggangmycin and preparation method |
| CN102067851A (en) * | 2011-01-20 | 2011-05-25 | 陕西美邦农药有限公司 | Antibacterial composition containing polyoxin and methoxyacrylate compound |
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| CN1191670A (en) * | 1998-02-10 | 1998-09-02 | 化工部沈阳化工研究院 | Pesticide and fungicide of unsaturated oximido ethers |
| EP0936213B1 (en) * | 1998-02-10 | 2003-03-26 | Dow AgroSciences LLC | Unsaturated oxime ethers and their use as fungicides and insecticides |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103039449A (en) * | 2011-10-11 | 2013-04-17 | 陕西上格之路生物科学有限公司 | Bactericidal composition |
| CN103039449B (en) * | 2011-10-11 | 2014-05-14 | 陕西上格之路生物科学有限公司 | Bactericidal composition |
| CN102972402A (en) * | 2012-12-18 | 2013-03-20 | 陕西绿盾生物制品有限责任公司 | Kasugamycin-containing pesticide composition |
| CN102972402B (en) * | 2012-12-18 | 2015-01-07 | 陕西绿盾生物制品有限责任公司 | Kasugamycin-containing pesticide composition |
| CN106172453A (en) * | 2015-04-29 | 2016-12-07 | 深圳诺普信农化股份有限公司 | A kind of bactericidal composition and application thereof |
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Address after: 715500 middle section of North Ring Road, Pucheng County, Shaanxi Applicant after: Shanxi Thompson Biological Technology Co., Ltd. Address before: 710075, C, 15 floor, Jinqiao International Plaza, science and technology road, hi tech Zone, Shaanxi, Xi'an Applicant before: Shanxi Thompson Biological Technology Co., Ltd. |
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Application publication date: 20111005 |